CN107412137A - A kind of skin care compositions of the light line of radiation proof and preparation method thereof - Google Patents
A kind of skin care compositions of the light line of radiation proof and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
Abstract
The invention discloses a kind of skin care compositions of the light line of radiation proof, in parts by weight, it is made up of 5~12 parts of vitamin A, 5~12 parts of vitamin C, 8~15 parts of vitamin E, 3~8 parts of vitaminF, 4~9 parts of citrin, 1~5 part of vitamin K, 7~16 parts of sour cherry extract, 6~15 parts of pomegranate berry extract, 12~20 parts of papaya extractives, 8~12 parts of cysteine, 0.5~3 part of enzyme modification rutin sophorin, 5~8 parts of pearl powder etc..Also disclose its preparation method.A kind of skin care compositions of the light line of radiation proof provided by the invention, can effectively eliminate free radical, have good radiation-resisting functional.Ultraviolet damage skin can be prevented, prevents skin from being tanned severely by sunlight, the generation of wrinkle caused by reducing UV light.
Description
Technical field
The present invention relates to skin care compositions of the light line of a kind of radiation proof and preparation method thereof, particularly belongs to skin care item technology neck
Domain.
Background technology
Skin care item, that is, protect the skin-protection product of skin.With the continuous progress of social economy and abundant, the shield of material life
Skin product, no longer it is there was only the thing risen of the rich just in the past.Nowadays skin care item have come into ordinary citizen house as the popular vehicles.It gives people
Spirit, image enhancing serve great effect.Radiation is inevitably touched in routine work life, electromagnetic radiation is
The fourth-largest environomental pollution source after water source, air, noise is classified as by the World Health Organization, turns into and endangers the hidden of human health
Shape " killer ".In in the 2005 Chinese residents common skin diseases reasons sequence of health ministry issue, electromagnetic radiation
First place is occupied in city dweller, in the data that the World Health Organization announces, because radiation-induced skin cancer accounts for global skin
A quarter in skin cancer patient numbers.It is more and more wider with the coverage of low frequency radiation, mainly act on resistance electrical equipment institute
Thus caused radiation skin care item are born.With advancing age, skin is also easy to produce wrinkle, and the reason for producing wrinkle is mainly divided to two
Major class：Chronological aging (natural aging) and external cause aging (light aging and smoking, excessive drinking, bad diet etc.).In order to tackle wrinkle
Generation, increasing light line product occurs in daily life.Produced in existing skin-protection product for daily radiation and wrinkle
Raw prevention effect is still undesirable, and research is a kind of being capable of effective skin care item of radiation proof and light line, it appears particularly necessary.
The content of the invention
To solve the deficiencies in the prior art, it is an object of the invention to provide a kind of skin care compositions of the light line of radiation proof and
Its preparation method, there is good light line effect, while can effectively reduce damage of the radiation to skin；Preparation method is simple,
It is easy to operate.
In order to realize above-mentioned target, the present invention adopts the following technical scheme that：
A kind of skin care compositions of the light line of radiation proof, in parts by weight, is made up of following components：Vitamin A 5~
12 parts, 5~12 parts of vitamin C, 8~15 parts of vitamin E, 3~8 parts of vitaminF, 4~9 parts of citrin, vitamin K 1
~5 parts, 7~16 parts of sour cherry extract, 6~15 parts of pomegranate berry extract, 12~20 parts of papaya extractives, cysteine
8~12 parts, 0.5~3 part of enzyme modification rutin sophorin, 5~8 parts of pearl powder, 5~8 parts of safranine flower extract, 3~6 parts of apple polyphenol,
0.5~2 part of grape seed extract, 1~3 part of Pine Bark, 2~6 parts of Astragalus Root P.E, 2~6 parts of ginseng extract, pellet
3~6 parts of conopsea extraction, 2~5 parts of angelica extract, 2~5 parts of Gentrin Knotweed P.E, 15~20 parts of emulsifying agent, NMF 10~15
120~240 parts of part, 3~10 parts of ultra-violet absorber and deionized water.
Further, the skin care compositions of the light line of foregoing radiation proof, in parts by weight, is made up of following components：Dimension
Raw plain 9~12 parts of A, 8~12 parts of vitamin C, 8~11 parts of vitamin E, 5~8 parts of vitaminF, 4~7 parts of citrin,
1~3 part of vitamin K, 7~12 parts of sour cherry extract, 10~15 parts of pomegranate berry extract, papaya extractives 12~18
Part, 8~11 parts of cysteine, 0.5~2 part of enzyme modification rutin sophorin, 5~8 parts of pearl powder, 5~8 parts of safranine flower extract, apple
3~5 parts of polyphenol, 0.5~2 part of grape seed extract, 1~3 part of Pine Bark, 2~4 parts of Astragalus Root P.E, ginseng extraction
2~5 parts of thing, 3~6 parts of Salvia root P.E, 2~5 parts of angelica extract, 2~5 parts of Gentrin Knotweed P.E, 17~20 parts of emulsifying agent, guarantor
180~240 parts of 12~15 parts of humectant, 5~10 parts of ultra-violet absorber and deionized water.
Preferably, the skin care compositions of the light line of foregoing radiation proof, in parts by weight, is made up of following components：Dimension life
Plain 10 parts of A, 9 parts of vitamin C, 10 parts of vitamin E, 7 parts of vitaminF, 5.5 parts of citrin, 2 parts of vitamin K, Europe
10.5 parts of sour cherry extract, 13 parts of pomegranate berry extract, 14 parts of papaya extractives, 9 parts of cysteine, enzyme modification rutin sophorin
1.2 parts, 6 parts of pearl powder, 7 parts of safranine flower extract, 3.5 parts of apple polyphenol, 1 part of grape seed extract, Pine Bark 2
Part, 3 parts of Astragalus Root P.E, 3 parts of ginseng extract, 5 parts of Salvia root P.E, 4 parts of angelica extract, 3.5 parts of Gentrin Knotweed P.E, breast
225 parts of 18 parts of agent, 13 parts of NMF, 9 parts of ultra-violet absorber and deionized water.
In the skin care compositions of the foregoing light line of radiation proof, emulsifying agent is polyoxyethylene laurel ether, six ethylene glycol monostearates
Ester or polyoxypropylene stearate.
In the skin care compositions of the foregoing light line of radiation proof, NMF is sodium lactate solution, DL- pyrrolidone sodium carboxylate solution
Or polyethylene glycol.
In the skin care compositions of the foregoing light line of radiation proof, ultra-violet absorber is salicylic acid -4- isopropyls benzyl ester, 4- first
Base -6- methoxy coumarins or Hypericum Chinense leaching juice.
A kind of preparation method of the skin care compositions of the light line of radiation proof, comprises the following steps：(1) by measure vitamin A, dimension
Raw plain E, vitamin K and pearl powder, 5~15min is stirred under the conditions of 1800~2200r/min, it is standby to obtain mixture A；
(2) carry by measuring vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw
The deionized water of thing, cysteine, enzyme modification rutin sophorin, grape seed extract, Pine Bark and 20%~40% amount is taken,
35 DEG C~45 DEG C are heated to while stirring, stir 30~45min, it is standby to obtain mixture B；
(3) by measuring safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis
Extract, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are heated to 45 DEG C while stirring
0.5~1h, subsequent 15~25min of ultrasonic vibration are stirred after~55 DEG C, mixture A and mixture B is added, is warming up to 60 DEG C~70
DEG C, 1.5~2.5h is stirred, slow cooling high-speed stirred 10min, produces to 50 DEG C.
Preferably, the preparation method of the skin care compositions of the light line of foregoing radiation proof, comprises the following steps：(1) by measure dimension
Raw plain A, vitamin E, vitamin K and pearl powder, 10min is stirred under the conditions of 2000r/min, it is standby to obtain mixture A；
(2) carry by measuring vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw
Take the deionized water of thing, cysteine, enzyme modification rutin sophorin, grape seed extract, Pine Bark and 30% amount, side stirring
While being heated to 40 DEG C, 40min is stirred, it is standby to obtain mixture B；
(3) by measuring safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis
Extract, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are heated to 50 DEG C while stirring
After stir 0.75h, subsequent ultrasonic vibration 20min, add mixture A and mixture B, be warming up to 65 DEG C, stir 2h, slow cooling
To 50 DEG C, high-speed stirred 10min, produce.
The present invention is advantageous in that：A kind of skin care compositions of the light line of radiation proof provided by the invention, can be effective
Elimination free radical, there is good radiation-resisting functional.Ultraviolet damage skin can be prevented, prevents skin from being tanned severely by sunlight,
The generation of wrinkle caused by reducing UV light.The skin care compositions set multivitamin and fruit extract of the present invention, both are common
Same-action, cell division, activating cell can be stimulated, thicken epidermis, improve skin elasticity, stimulation collagen is formed, had
Good light line function.Skin regeneration can also be promoted, play a part of Firm, skin care.The composition of the present invention can be flesh
Skin keeps the skin wet, and water lock performance is good.Also there is good anti-oxidation function, can effectively prevent the oxidative damage of skin.This hair
Bright composition effectively improves anti-inflammatory, the anti-inflammatory work(of skin care compositions also by gathering several kinds of Chinese medicinal materials and its extract
Can, improve anti-aging and light line characteristic.The skin care item of the present invention are safe and non-stimulating, have no toxic side effect.The preparation side of the present invention
Method is simple to operate, and reaction condition is gentle, easily controllable, and products obtained therefrom stability is high, and production cost is low.
Embodiment
The present invention is further introduced below in conjunction with specific embodiment.
Embodiment 1
A kind of skin care compositions of the light line of radiation proof, in parts by weight, is made up of following components：5 parts of vitamin A,
5 parts of vitamin C, 8 parts of vitamin E, 3 parts of vitaminF, 4 parts of citrin, 1 part of vitamin K, sour cherry extract 7
Part, 6 parts of pomegranate berry extract, 12 parts of papaya extractives, 8 parts of cysteine, 0.5 part of enzyme modification rutin sophorin, 5 parts of pearl powder, hide
5 parts of safflower extract, 3 parts of apple polyphenol, 0.5 part of grape seed extract, 1 part of Pine Bark, 2 parts of Astragalus Root P.E, people
2 parts of conopsea extraction, 3 parts of Salvia root P.E, 2 parts of angelica extract, 2 parts of Gentrin Knotweed P.E, 15 parts of emulsifying agent, 10 parts of NMF,
120 parts of 3 parts of ultra-violet absorber and deionized water.Emulsifying agent is polyoxyethylene laurel ether.NMF is polyethylene glycol.Ultraviolet
Absorbent is salicylic acid -4- isopropyl benzyl esters.
Embodiment 2
A kind of skin care compositions of the light line of radiation proof, in parts by weight, is made up of following components：Vitamin A 12
Part, 12 parts of vitamin C, 15 parts of vitamin E, 8 parts of vitaminF, 9 parts of citrin, 5 parts of vitamin K, sour cherry carry
Take 16 parts of thing, 15 parts of pomegranate berry extract, 20 parts of papaya extractives, 12 parts of cysteine, 3 parts of enzyme modification rutin sophorin, pearl powder 8
Part, 8 parts of safranine flower extract, 6 parts of apple polyphenol, 2 parts of grape seed extract, 3 parts of Pine Bark, 6 parts of Astragalus Root P.E,
6 parts of ginseng extract, 6 parts of Salvia root P.E, 5 parts of angelica extract, 5 parts of Gentrin Knotweed P.E, 20 parts of emulsifying agent, NMF 15
240 parts of part, 10 parts of ultra-violet absorber and deionized water.Emulsifying agent is six ethylene glycol monostearates.NMF is DL- pyrroles
Alkanone carboxylic acid sodium solution.Ultra-violet absorber is 4- methyl -6- methoxy coumarins.
Embodiment 3
A kind of skin care compositions of the light line of radiation proof, in parts by weight, is made up of following components：9 parts of vitamin A,
8 parts of vitamin C, 11 parts of vitamin E, 5 parts of vitaminF, 7 parts of citrin, 3 parts of vitamin K, sour cherry extract
12 parts, 10 parts of pomegranate berry extract, 18 parts of papaya extractives, 11 parts of cysteine, 2 parts of enzyme modification rutin sophorin, 7 parts of pearl powder,
6 parts of safranine flower extract, 5 parts of apple polyphenol, 1.5 parts of grape seed extract, 2.5 parts of Pine Bark, Astragalus Root P.E 4
Part, 5 parts of ginseng extract, 4 parts of Salvia root P.E, 3 parts of angelica extract, 3 parts of Gentrin Knotweed P.E, 17 parts of emulsifying agent, NMF
180 parts of 12 parts, 5 parts of ultra-violet absorber and deionized water.Emulsifying agent is polyoxypropylene stearate.NMF is that sodium lactate is molten
Liquid.Ultra-violet absorber is that Hypericum Chinense soaks juice.
Embodiment 4
A kind of skin care compositions of the light line of radiation proof, in parts by weight, is made up of following components：Vitamin A 11
Part, 10 parts of vitamin C, 9 parts of vitamin E, 6 parts of vitaminF, 6.5 parts of citrin, 2.3 parts of vitamin K, the sour cherry in Europe
9 parts of peach extract, 14 parts of pomegranate berry extract, 17 parts of papaya extractives, 10 parts of cysteine, 0.9 part of enzyme modification rutin sophorin, treasure
7.5 parts of pearl powder, 5.5 parts of safranine flower extract, 4 parts of apple polyphenol, 1.8 parts of grape seed extract, 1.5 parts of Pine Bark,
3.7 parts of Astragalus Root P.E, 4 parts of ginseng extract, 4.5 parts of Salvia root P.E, 3.5 parts of angelica extract, 4 parts of Gentrin Knotweed P.E,
200 parts of 19 parts of emulsifying agent, 14 parts of NMF, 8 parts of ultra-violet absorber and deionized water.Emulsifying agent is polyoxyethylene laurel ether.
NMF is sodium lactate solution.Ultra-violet absorber is 4- methyl -6- methoxy coumarins.
Embodiment 5
A kind of skin care compositions of the light line of radiation proof, in parts by weight, is made up of following components：Vitamin A 10
Part, 9 parts of vitamin C, 10 parts of vitamin E, 7 parts of vitaminF, 5.5 parts of citrin, 2 parts of vitamin K, sour cherry
10.5 parts of extract, 13 parts of pomegranate berry extract, 14 parts of papaya extractives, 9 parts of cysteine, 1.2 parts of enzyme modification rutin sophorin, treasure
6 parts of pearl powder, 7 parts of safranine flower extract, 3.5 parts of apple polyphenol, 1 part of grape seed extract, 2 parts of Pine Bark, the Radix Astragali carry
Take 3 parts of thing, 3 parts of ginseng extract, 5 parts of Salvia root P.E, 4 parts of angelica extract, 3.5 parts of Gentrin Knotweed P.E, 18 parts of emulsifying agent,
225 parts of 13 parts of NMF, 9 parts of ultra-violet absorber and deionized water.Emulsifying agent is six ethylene glycol monostearates.NMF is
Polyethylene glycol.Ultra-violet absorber is salicylic acid -4- isopropyl benzyl esters.
The skin care compositions of the light line of radiation proof is prepared by method in embodiment 6~8 in embodiment 1~5.
Embodiment 6
A kind of preparation method of the skin care compositions of the light line of radiation proof, comprises the following steps：(1) by measure vitamin A, dimension
Raw plain E, vitamin K and pearl powder, 15min is stirred under the conditions of 1800r/min, it is standby to obtain mixture A；
(2) carry by measuring vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw
Take the deionized water of thing, cysteine, enzyme modification rutin sophorin, grape seed extract, Pine Bark and 20% amount, side stirring
While being heated to 35 DEG C, 45min is stirred, it is standby to obtain mixture B；
(3) by measuring safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis
Extract, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are heated to 45 DEG C while stirring
After stir 1h, subsequent ultrasonic vibration 15min, add mixture A and mixture B, be warming up to 60 DEG C, stir 2.5h, slow cooling
To 50 DEG C, high-speed stirred 10min, produce.
Embodiment 7
A kind of preparation method of the skin care compositions of the light line of radiation proof, comprises the following steps：(1) by measure vitamin A, dimension
Raw plain E, vitamin K and pearl powder, 5min is stirred under the conditions of 2200r/min, it is standby to obtain mixture A；
(2) carry by measuring vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw
Take the deionized water of thing, cysteine, enzyme modification rutin sophorin, grape seed extract, Pine Bark and 40% amount, side stirring
While being heated to 45 DEG C, 30min is stirred, it is standby to obtain mixture B；
(3) by measuring safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis
Extract, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are heated to 55 DEG C while stirring
After stir 0.5h, subsequent ultrasonic vibration 25min, add mixture A and mixture B, be warming up to 70 DEG C, stir 1.5h, slowly drop
Temperature high-speed stirred 10min, produces to 50 DEG C.
Embodiment 8
A kind of preparation method of the skin care compositions of the light line of radiation proof, comprises the following steps：(1) by measure vitamin A, dimension
Raw plain E, vitamin K and pearl powder, 10min is stirred under the conditions of 2000r/min, it is standby to obtain mixture A；
(2) carry by measuring vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw
Take the deionized water of thing, cysteine, enzyme modification rutin sophorin, grape seed extract, Pine Bark and 30% amount, side stirring
While being heated to 40 DEG C, 40min is stirred, it is standby to obtain mixture B；
(3) by measuring safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis
Extract, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are heated to 50 DEG C while stirring
After stir 0.75h, subsequent ultrasonic vibration 20min, add mixture A and mixture B, be warming up to 65 DEG C, stir 2h, slow cooling
To 50 DEG C, high-speed stirred 10min, produce.
A series of experiments is carried out to skin care compositions in embodiment 1~5, concrete outcome is analyzed as follows.
1st, radicals scavenging is tested
The skin care compositions of Example 1~5,6 repetitions are set, determine reagent according to Hydroxyl radical-scavenging ability respectively
Box, superoxide anion Scavenging activity kit are measured.Experimental result is as shown in table 1 below.
Table 1
As shown in Table 1, product of the invention can effectively eliminate free radical.
2nd, radiation proof is tested
(1) skin care compositions of the embodiment of the present invention 1~5 is taken, adds the test that deionized water is configured to 0.025g/mL
Liquid；Blank control group is used as using deionized water.Successively in UV A areas 400nm, 380nm, 360nm, 340nm, 320nm, UVB
Area 320nm, 300nm, 280nm, UVC areas 280nm, 260nm, 246nm, 240nm, 220nm, 200nm, determine the saturating of each test liquid
Light rate, parallel determination 5 times (n=5), according to formula A%=100%-T%, calculate average absorption ratio.As a result show：The present invention
Embodiment 1~5 skin care compositions average absorption ratio more than 90%, wherein, the absorptivity of embodiment 4 and embodiment 5 exists
More than 96%.Ultraviolet damage skin can be prevented by showing the skin care compositions of the present invention, prevent skin from being tanned severely by sunlight.
(2) healthy mice is chosen, setting area is 2cm × 2cm irradiation area respectively, is respectively coated in embodiment 1~5
Skin care compositions is not coated by any sample as blank group, coating commercially available prod is as a control group as sample sets.Carry out ultraviolet
Line irradiate 20min, then take UV-irradiating portion skin, prepare skin histology homogenate, detection MDA, SOD, GSH-Px, CAT,
Hyp is horizontal.As a result show, sample sets indices are above control group and blank group, show there is good radiation-proof effect.
Especially the sample of embodiment 4 and embodiment 5, indices are above similar sample.
3rd, Consumer's Experience is tested
Control group uses commercially available prod, once in the morning and once at night, is used continuously 4 months.The skincare composition of the sample group present invention
Thing (embodiment), once in the morning and once at night, it is used continuously 4 months.Before use, using being observed after 4 months, comparative evaluation is to wrinkle
The improvement situation of line, microgroove.Evaluation criterion is：4 grades improve (improve 76%~100%), 3 grades improve (improve 51%~
75%), 2 grades improve and (improve 26%~50%), and 1 grade improves and (improves 1%-25%), no improvement；Total improvement effective percentage=1 grade
+ 4 grades of improvement rates of+2 grades of improvement rate+3 grades of improvement rate improvement rate).As a result it is as shown in table 2.
Table 2
As shown in Table 2, improvement situation positive effect of the product of the present invention to wrinkle, microgroove.
Claims (8)
- A kind of 1. skin care compositions of the light line of radiation proof, it is characterised in that：In parts by weight, it is made up of following components：Dimension Raw plain 5~12 parts of A, 5~12 parts of vitamin C, 8~15 parts of vitamin E, 3~8 parts of vitaminF, 4~9 parts of citrin, 1~5 part of vitamin K, 7~16 parts of sour cherry extract, 6~15 parts of pomegranate berry extract, papaya extractives 12~20 Part, 8~12 parts of cysteine, 0.5~3 part of enzyme modification rutin sophorin, 5~8 parts of pearl powder, 5~8 parts of safranine flower extract, apple 3~6 parts of polyphenol, 0.5~2 part of grape seed extract, 1~3 part of Pine Bark, 2~6 parts of Astragalus Root P.E, ginseng extraction 2~6 parts of thing, 3~6 parts of Salvia root P.E, 2~5 parts of angelica extract, 2~5 parts of Gentrin Knotweed P.E, 15~20 parts of emulsifying agent, guarantor 120~240 parts of 10~15 parts of humectant, 3~10 parts of ultra-violet absorber and deionized water.
- 2. the skin care compositions of the light line of radiation proof according to claim 1, it is characterised in that：In parts by weight, by Following components is made：9~12 parts of vitamin A, 8~12 parts of vitamin C, 8~11 parts of vitamin E, 5~8 parts of vitaminF, 4~7 parts of citrin, 1~3 part of vitamin K, 7~12 parts of sour cherry extract, 10~15 parts of pomegranate berry extract, wood 12~18 parts of melon extract, 8~11 parts of cysteine, 0.5~2 part of enzyme modification rutin sophorin, 5~8 parts of pearl powder, safflower extraction 5~8 parts of thing, 3~5 parts of apple polyphenol, 0.5~2 part of grape seed extract, 1~3 part of Pine Bark, Astragalus Root P.E 2~ 4 parts, 2~5 parts of ginseng extract, 3~6 parts of Salvia root P.E, 2~5 parts of angelica extract, 2~5 parts of Gentrin Knotweed P.E, emulsification 180~240 parts of 17~20 parts of agent, 12~15 parts of NMF, 5~10 parts of ultra-violet absorber and deionized water.
- 3. the skin care compositions of the light line of radiation proof according to claim 1, it is characterised in that：In parts by weight, by Following components is made：10 parts of vitamin A, 9 parts of vitamin C, 10 parts of vitamin E, 7 parts of vitaminF, 5.5 parts of citrin, 2 parts of vitamin K, 10.5 parts of sour cherry extract, 13 parts of pomegranate berry extract, 14 parts of papaya extractives, cysteine 9 Part, 1.2 parts of enzyme modification rutin sophorin, 6 parts of pearl powder, 7 parts of safranine flower extract, 3.5 parts of apple polyphenol, 1 part of grape seed extract, 2 parts of Pine Bark, 3 parts of Astragalus Root P.E, 3 parts of ginseng extract, 5 parts of Salvia root P.E, 4 parts of angelica extract, giant knotweed 225 parts of 3.5 parts of extract, 18 parts of emulsifying agent, 13 parts of NMF, 9 parts of ultra-violet absorber and deionized water.
- 4. the skin care compositions of the light line of radiation proof according to claim 1, it is characterised in that：The emulsifying agent is polyoxy second Alkene bay ether, six ethylene glycol monostearates or polyoxypropylene stearate.
- 5. the skin care compositions of the light line of radiation proof according to claim 1, it is characterised in that：The NMF is sodium lactate Solution, DL- pyrrolidone sodium carboxylates solution or polyethylene glycol.
- 6. the skin care compositions of the light line of radiation proof according to claim 1, it is characterised in that：The ultra-violet absorber is Salicylic acid -4- isopropyls benzyl ester, 4- methyl -6- methoxy coumarins or Hypericum Chinense leaching juice.
- 7. the preparation method of the skin care compositions of the light line of radiation proof as described in any one of claim 1~6, it is characterised in that： Comprise the following steps：(1) by measuring VitAVitE, vitamin K and pearl powder, under the conditions of 1800~2200r/min 5~15min is stirred, it is standby to obtain mixture A；(2) by measure vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw extract Thing, cysteine, enzyme modification rutin sophorin, grape seed extract, the deionized water of Pine Bark and 20%~40% amount, side Stirring side is heated to 35 DEG C~45 DEG C, stirs 30~45min, it is standby to obtain mixture B；(3) by measure safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis extract Thing, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are heated to 45 DEG C~55 while stirring 0.5~1h, subsequent 15~25min of ultrasonic vibration are stirred after DEG C, mixture A and mixture B is added, is warming up to 60 DEG C~70 DEG C, 1.5~2.5h is stirred, slow cooling high-speed stirred 10min, produces to 50 DEG C.
- 8. the preparation method of the skin care compositions of the light line of radiation proof according to claim 7, it is characterised in that：Including following Step：(1) by VitAVitE, vitamin K and pearl powder is measured, 10min is stirred under the conditions of 2000r/min, is obtained mixed Compound A is standby；(2) by measure vitamin C, vitaminF, citrin, sour cherry extract, pomegranate berry extract, pawpaw extract Thing, cysteine, enzyme modification rutin sophorin, grape seed extract, the deionized water of Pine Bark and 30% amount, while stirring 40 DEG C are heated to, 40min is stirred, it is standby to obtain mixture B；(3) by measure safflower extract, apple polyphenol, Astragalus Root P.E, ginseng extract, Salvia root P.E, Radix Angelicae Sinensis extract Thing, Gentrin Knotweed P.E, emulsifying agent, NMF, ultra-violet absorber and remaining deionized water, are stirred after being heated to 50 DEG C while stirring 0.75h, subsequent ultrasonic vibration 20min are mixed, adds mixture A and mixture B, is warming up to 65 DEG C, stirs 2h, slow cooling to 50 DEG C, high-speed stirred 10min, produce.
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Cited By (1)
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Application publication date: 20171201 |