CN107405362A - 抗dll3嵌合抗原受体及其使用方法 - Google Patents

抗dll3嵌合抗原受体及其使用方法 Download PDF

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Publication number
CN107405362A
CN107405362A CN201680019227.8A CN201680019227A CN107405362A CN 107405362 A CN107405362 A CN 107405362A CN 201680019227 A CN201680019227 A CN 201680019227A CN 107405362 A CN107405362 A CN 107405362A
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seq
dll3
cells
antibody
car
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P·A·伊斯卡普
S·J·戴拉
D·刘
R·A·司徒
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Abbo Wisch Te Musen Tex LLC
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Abbo Wisch Te Musen Tex LLC
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CN201680019227.8A 2015-02-23 2016-02-23 抗dll3嵌合抗原受体及其使用方法 Pending CN107405362A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562119793P 2015-02-23 2015-02-23
US62/119,793 2015-02-23
US201562241662P 2015-10-14 2015-10-14
US62/241,662 2015-10-14
US201662296560P 2016-02-17 2016-02-17
US62/296,560 2016-02-17
PCT/US2016/019192 WO2016138038A1 (en) 2015-02-23 2016-02-23 Anti-dll3 chimeric antigen receptors and methods of use

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CN107405362A true CN107405362A (zh) 2017-11-28

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CN201680019227.8A Pending CN107405362A (zh) 2015-02-23 2016-02-23 抗dll3嵌合抗原受体及其使用方法

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EP (1) EP3261650A4 (cg-RX-API-DMAC7.html)
JP (1) JP2018506981A (cg-RX-API-DMAC7.html)
KR (1) KR20170120158A (cg-RX-API-DMAC7.html)
CN (1) CN107405362A (cg-RX-API-DMAC7.html)
BR (1) BR112017017927A2 (cg-RX-API-DMAC7.html)
CA (1) CA2977502A1 (cg-RX-API-DMAC7.html)
CL (1) CL2017002150A1 (cg-RX-API-DMAC7.html)
CO (1) CO2017008804A2 (cg-RX-API-DMAC7.html)
CR (1) CR20170436A (cg-RX-API-DMAC7.html)
DO (1) DOP2017000199A (cg-RX-API-DMAC7.html)
EA (1) EA201791884A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP17063327A (cg-RX-API-DMAC7.html)
HK (1) HK1249405A1 (cg-RX-API-DMAC7.html)
IL (1) IL254068A0 (cg-RX-API-DMAC7.html)
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MX (1) MX2017010845A (cg-RX-API-DMAC7.html)
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SG (1) SG11201706804SA (cg-RX-API-DMAC7.html)
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CN112334193A (zh) * 2018-04-10 2021-02-05 美国安进公司 Dll3的嵌合受体及其使用方法
CN113444174A (zh) * 2020-03-25 2021-09-28 兴盟生物医药(苏州)有限公司 金黄色葡萄球菌α-毒素特异性抗体及其应用
CN113543799A (zh) * 2019-03-01 2021-10-22 艾洛基治疗公司 靶向dll3的嵌合抗原受体和结合剂
CN113795262A (zh) * 2019-04-08 2021-12-14 东莞凡恩世生物医药有限公司 人源化抗dll3嵌合抗原受体及其用途
WO2022206994A1 (en) * 2021-04-02 2022-10-06 Nanjing Legend Biotech Co., Ltd. Engineered immune cells and uses thereof
CN117169518A (zh) * 2023-11-03 2023-12-05 赛德特(北京)生物工程有限公司 T淋巴细胞制剂中的cd3抗体残留物的检测方法和试剂盒

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GB201403972D0 (en) 2014-03-06 2014-04-23 Ucl Business Plc Chimeric antigen receptor
SG10202002131PA (en) 2015-05-21 2020-05-28 Harpoon Therapeutics Inc Trispecific binding proteins and methods of use
CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技（香港）有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
KR20250089564A (ko) 2017-02-08 2025-06-18 드래곤플라이 쎄라퓨틱스, 인크. 천연 킬러 세포의 활성화를 위한 다중-특이적 결합 단백질 및 암 치료에서의 그의 치료적 용도
KR20190120782A (ko) 2017-02-20 2019-10-24 드래곤플라이 쎄라퓨틱스, 인크. Her2, nkg2d 및 cd16에 결합하는 단백질
AU2018304711B2 (en) * 2017-07-20 2025-04-10 Cytomx Therapeutics, Inc. Methods of qualitatively and/or quantitatively analyzing properties of activatable antibodies and uses thereof
KR102172092B1 (ko) 2017-09-19 2020-10-30 주식회사 엘지화학 열가소성 수지 조성물, 이의 제조방법 및 성형품
LT3694529T (lt) 2017-10-13 2024-10-10 Harpoon Therapeutics, Inc. Trispecifiniai baltymai ir panaudojimo būdai
IL315737A (en) 2017-10-13 2024-11-01 Harpoon Therapeutics Inc B-cell maturation antigen-binding proteins
US20190117153A1 (en) * 2017-10-20 2019-04-25 Nantbio, Inc. Methods for monitoring bladder cancer immunotherapy
PE20210375A1 (es) 2018-02-08 2021-03-02 Dragonfly Therapeutics Inc Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales
CA3090244A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
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