CN107397865A - A kind of additive for preventing and treating infectious bronchitis of chicken - Google Patents
A kind of additive for preventing and treating infectious bronchitis of chicken Download PDFInfo
- Publication number
- CN107397865A CN107397865A CN201710633476.2A CN201710633476A CN107397865A CN 107397865 A CN107397865 A CN 107397865A CN 201710633476 A CN201710633476 A CN 201710633476A CN 107397865 A CN107397865 A CN 107397865A
- Authority
- CN
- China
- Prior art keywords
- chicken
- infectious bronchitis
- herb
- additive
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to veterinary drug technical field, more particularly to a kind of additive for preventing and treating infectious bronchitis of chicken；Including following raw material：Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan；The additive of the present invention, there is significant prevention effect to infectious bronchitis of chicken, the incidence of disease of infectious bronchitis of chicken is effectively reduced to 10.2%, to the cure rate of infectious bronchitis of chicken more than 94%, effectively kill pathogen and its virus of infection infectious bronchitis of chicken, the prevention effect of infectious bronchitis of chicken is effectively improved, to improving chicken production performance, reduction economic loss, promoting chicken aquaculture sustainable and healthy development to play extremely important meaning.
Description
Technical field
The present invention relates to veterinary drug technical field, more particularly to a kind of additive for preventing and treating infectious bronchitis of chicken.
Background technology
Chicken cultivates the extension as agricultural industry, and highly important position is not only occupied in Chinese tradition aquaculture, and
And leading position is in the production of poultry industry always, the sound development of chicken aquaculture industry is the important channel for solving increasing peasant income
One of, and one of ensure important sources of the carnivorous consumption of resident, development chicken aquaculture industry be promote Chinese farmers increase wealth,
The important channel of Surplus Labor Power Quantity, the stable supply of chicken meat product, which has become, solves increasing peasant income and national economy
Important step, but frequently-occurring and very harmful infectious bronchitis of chicken is serious to hinder chicken aquaculture to develop in a healthy way
Stumbling-block.
Infectious bronchitis of chicken is a kind of acute highly contagious disease as caused by infectious bronchitis virus,
Infected chicken feed consumption increase, is laid eggs and the decline of egg matter, death and culling rate increase because of growth retardation, huge economic losses is caused to poultry husbandry.
It is characterized in that have difficulty in breathing, send rale, cough, mouth breathing, sneezing.This sick infected chicken, without obvious breed difference.This
Sick infected chicken, without obvious breed difference.The chicken of various ages in days is all susceptible, but the chicken symptom in 5 week old is more apparent, and the death rate can
To 15-19%.Morbidity season is more common in Qiu Mozhi late springs next year, but the most serious with winter, is the main disease for endangering poultry husbandry
One of disease, major lesions are in respiratory tract.In nasal cavity, trachea-bronchial epithelial cell, it is seen that have faint yellow translucent serosity, mucus
Property exudate, the course of disease is slightly long to be changed into caseous substance and forms embolus.Air bag may be muddy or contains caseous exudate.Production
The hyperemia of egg hen ovarian follicle, bleeding or deformation；Fallopian tubal is short and thick, plump, contrafluxion, necrosis.Chickens Infected this disease then fallopian tubal
It is permanent during infringement, grow up it is latter as can not lay eggs.Nephrosis modification bronchitis is in addition to respiratory apparatus lesion, it is seen that kidney swells
Greatly, it is pale, uric acid mineralization in renal tubule and expand, kidney is in graniphyric, ureter uric acid mineralization and it is thicker.The heart, liver surface
Also there is the lithate of deposition like one layer of bloom.Sometimes the visible bursa of farbricius has inflammation and bleeding.
Chinese herbal medicine has the advantages that medicine source is extensive, the efficient, resistance to the action of a drug is not notable, toxic side effect is small at present, is passed in preventing and treating chicken
During metachromia bronchitis, in addition to having the property of medicine and trophism concurrently, also there is the production performance and efficiency of feed utilization for improving chicken
The effect of, so being increasingly taken seriously, application is also increasingly extensive, so, in view of a series of features of Chinese herbal medicine, by Chinese herbal medicine
Being used in the preventing and treating of infectious bronchitis of chicken has positive effect, such as application number 201610359690.9《One kind is anti-
Control the Chinese medicine composition of infectious bronchitis of chicken》A kind of Chinese medicine composition for preventing and treating infectious bronchitis of chicken is disclosed, is
By alum, Chinese trumpet creeper, the tuber of pinellia, rhizoma zingiberis, Flos Magnoliae Liliflorae, almond, balloonflower root, silvervine actinidia root, tendril-leaved fritillary bulb, the Radix Astragali, the root of Dahurain angelica, kelp, Sword Jackbean Seed,
The tuber of stemona, radix glycyrrhizae and the dried venom of toads composition, but from existing patent with from the point of view of paper, for the Chinese herbal medicine of infectious bronchitis of chicken
Though the research of preparation obtains certain effect, because the formula of current preparation is unreasonable, and infectious bronchitis of chicken hair
The randomness of disease and it is frequently-occurring the features such as so that current Chinese medicine prevention effect is less desirable, causes to have occurred morbidity
Rate is very high, the very low phenomenon of cure rate, the development of chicken aquaculture is seriously constrained, therefore, for infectious bronchitis
The characteristics of incidence of opportunistic pathogen, the incidence of disease is reduced, improve infectious bronchitis of chicken cure rate, the sound development to chicken aquaculture has
Important realistic meaning and economic implications.
The content of the invention
The present invention is in order to solve the above technical problems, provide a kind of additive for preventing and treating infectious bronchitis of chicken.
Realized particular by following technical scheme：
A kind of additive for preventing and treating infectious bronchitis of chicken, including following raw material by weight：Lygodium japonicum 20~
30th, loguat leaf 12~18, bark of ash 6~9, the fruit of Cherokee rose 8~12, geranium wilfordii 15~25, rattletop 8~12, sweet wormwood 3~8, elscholtiza 10~
20th, Japanese ardisia 15~25, field pennycress 6~9, Common Sage Herb 15~25, glabrous pogestemon herb 8~12, Swamp Mahogany Leaf 10~20, broomwort 6
~9, rhizoma dioscoreae nipponicae 8~12, the flower bud of lily magnolia 5~15, tealeaves 6~9, garlic 3~5, flatstiped corydalis herb 8~12, yellow gelsemium elegan 5~8, compound benefit
Raw bacterium 8~12.
Further, including following raw material by weight：Lygodium japonicum 25, loguat leaf 15, bark of ash 8, the fruit of Cherokee rose 10, old stork
Grass 20, rattletop 10, sweet wormwood 5, elscholtiza 15, Japanese ardisia 20, field pennycress 8, Common Sage Herb 20, glabrous pogestemon herb 10, Swamp Mahogany Leaf 15, open country are sweet
Grass 8, rhizoma dioscoreae nipponicae 10, the flower bud of lily magnolia 10, tealeaves 8, garlic 4, flatstiped corydalis herb 10, yellow gelsemium elegan 7, compound probiotic 10.
Described compound probiotic, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus by 0.5~
0.8：1：0.3~0.8：0.8~1.2 mass ratio is mixed to prepare.
The additive of described preventing and treating infectious bronchitis of chicken, is paste agent, granule, oral liquid and parenteral solution.
Described paste agent, it is by Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, level land
Wood, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, Huang Duan
After intestines grass is weighed by formula ratio, dries pulverizing obtains traditional Chinese medicine powder, and the water for adding 2~3 times of amounts of traditional Chinese medicine powder quality heats infusion into aqueous
The medicinal extract for 8~12% is measured, after cooling, is mixed with compound probiotic, you can.
Described granule, it is by Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, level land
Wood, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, Huang Duan
After intestines grass is weighed by formula ratio, dries pulverizing, traditional Chinese medicine powder is obtained, add 20~30% pregelatinized starch of traditional Chinese medicine powder quality, mix
It is even, infiltrated with ethanol, be granulated by comminutor.
Described oral liquid, it is by Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, level land
Wood, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, Huang Duan
After intestines grass is weighed by formula ratio, add water infusion, filter, add water infusion filter residue, in triplicate, filtrate will merge three times, concentration
To the 1/2 of amalgamation liquid volume, 20~30% syrup of concentrate quality is added, compound probiotic is added, mixes thoroughly.
Described parenteral solution, it is by Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, level land
Wood, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, Huang Duan
After intestines grass is weighed by formula ratio, crush, distilled with steam distillation, collect distillate, then carry out redistillation, collect redistillation
Liquid, adds 0.8~1.2% times of sodium chloride of re-distilled liquid quality, and 0.6~0.8% times of re-distilled liquid quality poly-
Sorb ester 80, stirring and dissolving, it is filtered until clear with G4 sintered glass funnels, embedding, sterilize 30min at 100 DEG C, you can.
In summary, the beneficial effects of the present invention are：The additive of the present invention, have to infectious bronchitis of chicken aobvious
The prevention effect of work, the incidence of disease of infectious bronchitis of chicken is effectively reduced to 10.2%, to infectious bronchitis of chicken
Cure rate effectively kills pathogen and its virus of infection infectious bronchitis of chicken more than 94%, and has broad spectrum activity,
Meanwhile the Immunoresistance of chicken is also improved, the resistance of itself is lifted, reduces the risk caught an illness, effectively improves chicken infection
Property bronchitis prevention effect, to improving chicken production performance, reducing economic loss, promote chicken aquaculture sustainable and healthy development hair
Extremely important meaning is waved.
Embodiment
The embodiment of the present invention is described in further detail below, but the invention is not limited in these realities
Mode is applied, any improvement or replacement on the present embodiment essence spirit, it is claimed to still fall within the claims in the present invention
Scope.
Embodiment 1
A kind of additive for preventing and treating infectious bronchitis of chicken, including following raw material by weight：Lygodium japonicum 20kg,
Loguat leaf 12kg, bark of ash 6kg, fruit of Cherokee rose 8kg, geranium wilfordii 15kg, rattletop 8kg, sweet wormwood 3kg, elscholtiza 10kg, Japanese ardisia 15kg,
Field pennycress 6kg, Common Sage Herb 15kg, glabrous pogestemon herb 8kg, Swamp Mahogany Leaf 10kg, broomwort 6kg, rhizoma dioscoreae nipponicae 8kg, flower bud of lily magnolia 5kg, tea
Leaf 6kg, garlic 3kg, flatstiped corydalis herb 8kg, yellow gelsemium elegan 5kg, compound probiotic 8kg.
Described compound probiotic, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus press 0.5：1：
0.3：0.8 mass ratio is mixed to prepare.
The additive of described preventing and treating infectious bronchitis of chicken, preparation method is by Lygodium japonicum, loguat leaf, bark of ash, gold
Cherry, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, Chuan Shan
After dragon, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, dries pulverizing, traditional Chinese medicine powder is obtained, add Chinese medicine
The water of 2~3 times of amounts of silty amount heats infusion into the medicinal extract that water content is 8~12%, after cooling, is mixed with compound probiotic, i.e.,
Obtain paste agent.
During prevention, the paste agent of preparation and daily grain of chicken are pressed 0.3~0.5%：1 mass ratio mixing, feeding is carried out to chicken,
When chicken falls ill, the paste agent of preparation and daily grain of chicken are pressed 0.8~1.2%：1 mass ratio mixing, feeding is carried out to chicken.
Embodiment 2
A kind of additive for preventing and treating infectious bronchitis of chicken, including following raw material by weight：Lygodium japonicum 30kg,
Loguat leaf 18kg, bark of ash 9kg, fruit of Cherokee rose 12kg, geranium wilfordii 25kg, rattletop 12kg, sweet wormwood 8kg, elscholtiza 20kg, Japanese ardisia
25kg, field pennycress 9kg, Common Sage Herb 25kg, glabrous pogestemon herb 12kg, Swamp Mahogany Leaf 20kg, broomwort 9kg, rhizoma dioscoreae nipponicae 12kg, the flower bud of lily magnolia
15kg, tealeaves kg, garlic 5kg, flatstiped corydalis herb 12kg, yellow gelsemium elegan 8kg, compound probiotic 12kg.
Described compound probiotic, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus press 0.8：1：
0.8：1.2 mass ratio is mixed to prepare.
The additive of described preventing and treating infectious bronchitis of chicken, preparation method is by Lygodium japonicum, loguat leaf, bark of ash, gold
Cherry, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, Chuan Shan
After dragon, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, dries pulverizing, traditional Chinese medicine powder is obtained, add Chinese medicine
20~30% pregelatinized starch of silty amount, mixes thoroughly, is infiltrated with ethanol, is granulated by comminutor, produce granule.
During prevention, the granule of preparation and daily grain of chicken are pressed 0.3~0.5%：1 mass ratio mixing, feeding is carried out to chicken,
When chicken falls ill, the granule of preparation and daily grain of chicken are pressed 0.8~1.2%：1 mass ratio mixing, feeding is carried out to chicken.
Embodiment 3
A kind of additive for preventing and treating infectious bronchitis of chicken, including following raw material by weight：Lygodium japonicum 25kg,
Loguat leaf 15kg, bark of ash 8kg, fruit of Cherokee rose 10kg, geranium wilfordii 20kg, rattletop 10kg, sweet wormwood 5kg, elscholtiza 15kg, Japanese ardisia
20kg, field pennycress 8kg, Common Sage Herb 20kg, glabrous pogestemon herb 10kg, Swamp Mahogany Leaf 15kg, broomwort 8kg, rhizoma dioscoreae nipponicae 10kg, the flower bud of lily magnolia
10kg, tealeaves 8kg, garlic 4kg, flatstiped corydalis herb 10kg, yellow gelsemium elegan 7kg, compound probiotic 10kg.
Described compound probiotic, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus press 0.7：1：
0.5：1 mass ratio is mixed to prepare.
The additive of described preventing and treating infectious bronchitis of chicken, preparation method is by Lygodium japonicum, loguat leaf, bark of ash, gold
Cherry, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, Chuan Shan
After dragon, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, add water infusion, filter, add water infusion filter
Slag, in triplicate, it filtrate will merge three times, and be concentrated into the 1/2 of amalgamation liquid volume, add 20~30% sugar of concentrate quality
Agent is starched, compound probiotic is added, mixes thoroughly, produce oral liquid.
During prevention, the oral liquid of preparation and daily grain of chicken are pressed 2~4%：1 mass ratio mixing, carries out feeding to chicken, works as chicken
During morbidity, the oral liquid of preparation is gavaged by 6~8ml/kg amount to chicken.
Embodiment 4
A kind of additive for preventing and treating infectious bronchitis of chicken, including following raw material by weight：Lygodium japonicum 20kg,
Loguat leaf 18kg, bark of ash 6kg, fruit of Cherokee rose 12kg, geranium wilfordii 15kg, rattletop 12kg, sweet wormwood 3kg, elscholtiza 20kg, Japanese ardisia
15kg, field pennycress 9kg, Common Sage Herb 15kg, glabrous pogestemon herb 12kg, Swamp Mahogany Leaf 10kg, broomwort 9kg, rhizoma dioscoreae nipponicae 8kg, the flower bud of lily magnolia
15kg, tealeaves 6kg, garlic 5kg, flatstiped corydalis herb 8kg, yellow gelsemium elegan 8kg, compound probiotic 8kg.
Described compound probiotic, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus press 0.5：1：
0.8：0.8 mass ratio is mixed to prepare.
The additive of described preventing and treating infectious bronchitis of chicken, preparation method is by Lygodium japonicum, loguat leaf, bark of ash, gold
Cherry, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, Chuan Shan
After dragon, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, crush, distilled with steam distillation, receive
Collect distillate, then carry out redistillation, collect re-distilled liquid, add 0.8~1.2% times of sodium chloride of re-distilled liquid quality, and
0.6~0.8% times of polyoxyethylene sorbitan monoleate of re-distilled liquid quality, stirring and dissolving, is filtered until clear with G4 sintered glass funnels, is filled
Seal, sterilize 30min at 100 DEG C, produces parenteral solution.
During prevention, the parenteral solution of preparation is pressed to 0.08~0.1ml/kg amount, chicken is injected, will when chicken falls ill
The parenteral solution of preparation is injected by 0.15~0.2ml/kg amount to chicken.
Embodiment 5
A kind of additive for preventing and treating infectious bronchitis of chicken, including following raw material by weight：Lygodium japonicum 30kg,
Loguat leaf 12kg, bark of ash 9kg, fruit of Cherokee rose 8kg, geranium wilfordii 25kg, rattletop 8kg, sweet wormwood 8kg, elscholtiza 10kg, Japanese ardisia 25kg,
Field pennycress 6kg, Common Sage Herb 25kg, glabrous pogestemon herb 8kg, Swamp Mahogany Leaf 20kg, broomwort 6kg, rhizoma dioscoreae nipponicae 12kg, flower bud of lily magnolia 5kg, tea
Leaf 9kg, garlic 3kg, flatstiped corydalis herb 12kg, yellow gelsemium elegan 5kg, compound probiotic 12kg.
Described compound probiotic, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus press 0.8：1：
0.3：1.2 mass ratio is mixed to prepare.
The additive of described preventing and treating infectious bronchitis of chicken, preparation method is by Lygodium japonicum, loguat leaf, bark of ash, gold
Cherry, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, glabrous pogestemon herb, Swamp Mahogany Leaf, broomwort, Chuan Shan
After dragon, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, add water infusion, filter, add water infusion filter
Slag, in triplicate, it filtrate will merge three times, and be concentrated into the 1/2 of amalgamation liquid volume, add 20~30% sugar of concentrate quality
Agent is starched, compound probiotic is added, mixes thoroughly, produce oral liquid.
During prevention, the oral liquid of preparation and daily grain of chicken are pressed 2~4%：1 mass ratio mixing, carries out feeding to chicken, works as chicken
During morbidity, the oral liquid of preparation is gavaged by 6~8ml/kg amount to chicken.
1st, randomly select health status, activity can stand by force, some of age identical chicken, be randomly divided into 2 groups, every group of chicken
Quantity is identical, is fed using daily management mode, and 2 groups of chickens are fed by same people, and difference is, first group
By the present embodiment 1~5 prepare any additive mixed with daily ration (specific combined amount with reference in embodiment 1~5 prevention when adding
Dosage), feeding is carried out to chicken, second group is added Application No. 201310514245.1 in daily ration《It is avian infectious for preventing
The immune formulation of bronchitis》Disclosed preparation, addition is with first group, and experimental period is 3 months, respectively to avian infectious branch
The incidence of disease of tracheitis is counted, as a result as shown in table 1：
Table 1
| Project | Incidence of disease % |
| First group | 11.4 |
| Second group | 17 |
2nd, some ages in the first year are randomly selected, make a definite diagnosis the chicken with infectious bronchitis of chicken through blood clotting, are randomly divided into 2 groups,
Fed using daily management mode, and fed by same people, difference is, first group by embodiment 1~5
Prepare any additive and (specific combined amount is with reference to addition when being treated in embodiment 1~5) is mixed with daily ration, chicken is fed
Food, second group is added Application No. 201310465972.3 in daily ration《A kind of Chinese medicine for treating broiler chicken infective bronchitis》
Disclosed medicine, addition are carried out to the treatment of infectious bronchitis of chicken respectively with first group, test period 20d
Statistics, as a result as shown in table 2：
Table 2
| Project | Cure rate % | Efficient % |
| First group | 95.5 | 97.3 |
| Second group | 93.2 | 95.6 |
3rd, the formulation of the embodiment of the present invention 1~5 is respectively paste agent, granule, oral liquid, parenteral solution, oral liquid, at random
Selection health status, activity can found strong, age some heads of identical chicken, be randomly divided into 6 groups, every group of quantity is identical, and use is daily
Way to manage is fed, and is fed by same people, and difference is, first group is respectively made the present embodiment 1~5
Standby any additive mixes (wherein mixed proportion is shown in embodiment 1~5) with daily ration, carries out feeding to chicken, the 6th group in daily ration
Add Application No. 201310514245.1《For preventing the immune formulation of infectious bronchitis of chicken》Disclosed preparation, add
The same 5 groups of dosage, feeding is carried out to chicken；When finding to make a definite diagnosis the chicken with infectious bronchitis of chicken through blood clotting, diseased chicken is isolated,
Any additive prepared by the present embodiment 1~5 is mixed into (wherein mixed proportion is shown in embodiment 1~6) with daily ration, chicken is fed
Food, the 6th group is added application number 201310465972.3 in daily ration《A kind of Chinese medicine for treating broiler chicken infective bronchitis》It is public
The medicine opened, addition is with the first 5 groups, and observing time is one month, and preventing and treating situation is counted respectively, as a result such as table 3
It is shown：
Table 3
Claims (8)
1. a kind of additive for preventing and treating infectious bronchitis of chicken, it is characterised in that including following raw material by weight：Sea
Jinsha 20~30, loguat leaf 12~18, bark of ash 6~9, the fruit of Cherokee rose 8~12, geranium wilfordii 15~25, rattletop 8~12, sweet wormwood 3~8,
Elscholtiza 10~20, Japanese ardisia 15~25, field pennycress 6~9, Common Sage Herb 15~25, glabrous pogestemon herb 8~12, Swamp Mahogany Leaf 10~20,
Broomwort 6~9, rhizoma dioscoreae nipponicae 8~12, the flower bud of lily magnolia 5~15, tealeaves 6~9, garlic 3~5, flatstiped corydalis herb 8~12, yellow gelsemium elegan 5~
8th, compound probiotic 8~12.
2. as claimed in claim 1 preventing and treating infectious bronchitis of chicken additive, it is characterised in that including it is following by weight
The raw material of part meter：Lygodium japonicum 25, loguat leaf 15, bark of ash 8, the fruit of Cherokee rose 10, geranium wilfordii 20, rattletop 10, sweet wormwood 5, elscholtiza 15, level land
It is wood 20, field pennycress 8, Common Sage Herb 20, glabrous pogestemon herb 10, Swamp Mahogany Leaf 15, broomwort 8, rhizoma dioscoreae nipponicae 10, the flower bud of lily magnolia 10, tealeaves 8, big
Garlic 4, flatstiped corydalis herb 10, yellow gelsemium elegan 7, compound probiotic 10.
3. the additive of preventing and treating infectious bronchitis of chicken as claimed in claim 1, it is characterised in that described is compound prebiotic
Bacterium, Lactobacillus casei, enterococcus faecalis, Lactobacillus rhamnosus and streptococcus thermophilus press 0.5~0.8：1：0.3~0.8：0.8~1.2
Mass ratio be mixed to prepare.
4. the additive of preventing and treating infectious bronchitis of chicken as claimed in claim 1, it is characterised in that for paste agent, particle
Agent, oral liquid and parenteral solution.
5. the additive of preventing and treating infectious bronchitis of chicken as claimed in claim 4, it is characterised in that described paste agent,
It is to hang Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, chicken
After bone grass, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, dry
Dry grinding, traditional Chinese medicine powder is obtained, the water for adding 2~3 times of amounts of traditional Chinese medicine powder quality heats infusion into the medicinal extract that water content is 8~12%, cold
But after, mixed with compound probiotic, you can.
6. the additive of preventing and treating infectious bronchitis of chicken as claimed in claim 4, it is characterised in that described granule,
It is to hang Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, chicken
After bone grass, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, dry
Dry grinding, traditional Chinese medicine powder is obtained, add 20~30% pregelatinized starch of traditional Chinese medicine powder quality, mix thoroughly, infiltrated with ethanol, pass through granulation
Machine is granulated.
7. the additive of preventing and treating infectious bronchitis of chicken as claimed in claim 4, it is characterised in that described oral liquid,
It is to hang Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, chicken
After bone grass, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, add
Water infusion, filtering, adds water infusion filter residue, in triplicate, filtrate will merge three times, and be concentrated into the 1/2 of amalgamation liquid volume, add
20~30% syrup of concentrate quality, adds compound probiotic, mixes thoroughly.
8. the additive of preventing and treating infectious bronchitis of chicken as claimed in claim 4, it is characterised in that described parenteral solution,
It is to hang Lygodium japonicum, loguat leaf, bark of ash, the fruit of Cherokee rose, geranium wilfordii, rattletop, sweet wormwood, elscholtiza, Japanese ardisia, field pennycress, Common Sage Herb, chicken
After bone grass, Swamp Mahogany Leaf, broomwort, rhizoma dioscoreae nipponicae, the flower bud of lily magnolia, tealeaves, garlic, flatstiped corydalis herb, yellow gelsemium elegan are weighed by formula ratio, powder
It is broken, distilled with steam distillation, collect distillate, then redistillation is carried out, re-distilled liquid is collected, adds re-distilled liquid quality
0.8~1.2% times of sodium chloride, and 0.6~0.8% times of polyoxyethylene sorbitan monoleate of re-distilled liquid quality, stirring and dissolving, are hung down with G4
Molten glass funnel is filtered until clear, embedding, and sterilize 30min at 100 DEG C, you can.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710633476.2A CN107397865A (en) | 2017-07-28 | 2017-07-28 | A kind of additive for preventing and treating infectious bronchitis of chicken |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710633476.2A CN107397865A (en) | 2017-07-28 | 2017-07-28 | A kind of additive for preventing and treating infectious bronchitis of chicken |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107397865A true CN107397865A (en) | 2017-11-28 |
Family
ID=60401656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710633476.2A Pending CN107397865A (en) | 2017-07-28 | 2017-07-28 | A kind of additive for preventing and treating infectious bronchitis of chicken |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107397865A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247514A (en) * | 2011-06-29 | 2011-11-23 | 北京康华远景科技有限公司 | Traditional Chinese medicine composite for treating Newcastle disease |
| CN103784700A (en) * | 2014-03-05 | 2014-05-14 | 四川天红牧业有限公司 | Compound preparation for preventing and treating respiratory diseases of beasts and birds |
-
2017
- 2017-07-28 CN CN201710633476.2A patent/CN107397865A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247514A (en) * | 2011-06-29 | 2011-11-23 | 北京康华远景科技有限公司 | Traditional Chinese medicine composite for treating Newcastle disease |
| CN103784700A (en) * | 2014-03-05 | 2014-05-14 | 四川天红牧业有限公司 | Compound preparation for preventing and treating respiratory diseases of beasts and birds |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1879745B (en) | A veterinary Chinese medicinal powder for treating avian viral disease | |
| CN104522320B (en) | A kind of natural plants anticoccidial feed addictive and its application | |
| CN104054972A (en) | Feed for raising river crab | |
| CN102240323B (en) | Traditional Chinese medicine for controlling aeromonas hydrophila disease of aquatic animals | |
| CN104431488A (en) | Preparation process of grass carp feed additive containing eucommia bark powder | |
| CN106039138A (en) | Lactic acid bacteria traditional Chinese medicine fermentation antiviral preparation for aquaculture | |
| CN103356767A (en) | Medicinal composition for treating bacterial diarrhea of livestock as well as preparation method and application thereof | |
| CN107252461A (en) | A kind of composition for preventing and treating swine fever | |
| KR20090037146A (en) | Non-antibiotics feed for raising poultry | |
| CN107397865A (en) | A kind of additive for preventing and treating infectious bronchitis of chicken | |
| CN101524479B (en) | Medicine for curing avian infectious bronchitis | |
| CN104840591B (en) | A kind of Chinese medicine composition for having effects that to prevent ewcastle disease | |
| CN104171540B (en) | A kind of weanling pig anti-diarrhea growth-promoting changqiang immunity compound Chinese herbal medicinal feed additive and preparation method thereof | |
| CN103859168B (en) | The anti-avian influenza feed addictive of a kind of large-scale ecological poultry and preparation thereof, using method | |
| CN104367670A (en) | Traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis and preparation method thereof | |
| CN106380324A (en) | Method for preparing organic fertilizer special for Chinese wampee fruit trees and prepared organic fertilizer | |
| CN107213344A (en) | A kind of composition for preventing and treating swine fever | |
| CN107296864A (en) | A kind of composition for preventing and treating checken pest | |
| CN107281368A (en) | A kind of feed addictive for preventing and treating swine plague | |
| CN105169000A (en) | Drug for preventing and treating winter dysentery of pigs and production method thereof | |
| CN110354194A (en) | Chinese medicine composition and preparation method thereof for preventing and treating porcine mycoplasmal pneumonia | |
| CN109156610A (en) | A kind of rotten shell disease Chinese herbal feed additive of prevention and treatment Procambius clarkii and the preparation method and application thereof | |
| CN1934988A (en) | Chinese herbal medicine compound fine-extracting prepartion for fishery animals | |
| CN104288260B (en) | A kind of herbal medicine of effective preventing and treating porcine respiratory disease | |
| CN107213384A (en) | A kind of composition for preventing and treating rabbit pest |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171128 |