CN107362116A - A kind of hair remover and its application - Google Patents

A kind of hair remover and its application Download PDF

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Publication number
CN107362116A
CN107362116A CN201710761775.4A CN201710761775A CN107362116A CN 107362116 A CN107362116 A CN 107362116A CN 201710761775 A CN201710761775 A CN 201710761775A CN 107362116 A CN107362116 A CN 107362116A
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CN
China
Prior art keywords
hair remover
ginger
hair
cordate houttuynia
flavones
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Pending
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CN201710761775.4A
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Chinese (zh)
Inventor
不公告发明人
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Guangzhou Poly Injection General Technology Research Institute Co Ltd
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Guangzhou Poly Injection General Technology Research Institute Co Ltd
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Priority to CN201710761775.4A priority Critical patent/CN107362116A/en
Publication of CN107362116A publication Critical patent/CN107362116A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q9/00Preparations for removing hair or for aiding hair removal
    • A61Q9/04Depilatories
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention discloses a kind of hair remover and its application, the hair remover is made up of the component of following mass percent:Ginger P.E 0.1 3.2%, papaya papain 0.2 2.5%, cordate houttuynia flavones 0.15 2.0%.The hair remover is applied in depilatory cream, not only can be with anti-inflammation and sterilization, skin care and Peppermint Extract, additionally it is possible to effective prevention and alleviation epifolliculitis.And preparation method is simple, hair removal effect is good, non-stimulated to skin, have no side effect.

Description

A kind of hair remover and its application
Technical field
The present invention relates to cosmetic field, and in particular to a kind of hair remover and its application.
Background technology
Beauty in the market is generally divided into three major types on the use of depilatory:Machinery depilation method, chemical defleecing method With physics depilating method;Wherein, 1, mechanical depilation is to pull out superfluous hairs using the tweezers of most original or razor device is scraped Division, its is easy to operate, but can not eradicate, and the hair regeneration time is short, and can easily cause hair follicle mistake using the repetition depilation of this method It is quick, it is unsuitable for large area depilation;2nd, chemical depilation is to be applied to local skin using depilatory cream, depilatory cream, depilation dew etc., is made Can be corroded, dissolve, being rapidly reached the effect of depilation after hair shaft, and Hair growth rate is slow, sustainable 2 weeks of effect with On, if but repeatedly, it is long-term use of skin may be caused to damage, or cause chemically, allergic dermatitis, in eye circumference, strength film group This method can not be used by knitting the region such as around;3rd, physics epilation is lost hair or feathers available for large area, the depilation gimmick commonly used for beauty parlor, Physics epilation typically uses depilatory cream, and depilatory cream is most original, safest depilatory, is divided into and freezes two kinds of wax and hot wax. The main component for freezing wax be various kinds of resin, and adherence is strong, water-soluble, jelly, during use does not have to heat, can be directly applied to take off Skin at hair, and closely adhered with skin, no sense of discomfort, suitable for sensitive part skin depilatory;Hot wax are that beeswax mixes with resin Conjunction forms, and typically in solid state, needs heating to dissolve before use, when temperature is reduced to suitable skin, can be coated on skin. It is easy to use to freeze wax, but cost is higher.Hot wax cost is relatively low, and used wax repeats after sterilizing, heat, filter off hair to be made With, but operate cumbersome, and should skillfully grasp the temperature of wax exactly, the too high easy skin ambustion of temperature, but temperature is relatively low also can Hair removal effect is influenceed, therefore is typically all used with hot wax depilation in beauty parlor.Moreover, depilatory cream currently on the market is almost required for Non-woven fabrics is higher as carrier, production cost.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of hair remover, its not only can with anti-inflammation and sterilization, Skin care and Peppermint Extract, additionally it is possible to effective prevention and alleviation epifolliculitis.And preparation method is simple, hair removal effect is good.
To achieve these goals, the present invention adopts the following technical scheme that:
A kind of hair remover includes the component of following mass percent:Ginger P.E 0.1-3.2%, papaya Papain Enzyme 0.2-2.5%, cordate houttuynia flavones 0.15-2.0%.
Preferably, described hair remover includes the component of following mass percent:Ginger P.E 0.25-2.7%, kind wood Melon papain 0.3-2.0%, cordate houttuynia flavones 0.3-1.6%.
Preferably, described hair remover includes the component of following mass percent:Ginger P.E 0.5-2.0%, kind wood Melon papain 0.5-1.5%, cordate houttuynia flavones 0.6-1.2%.
Further, the preparation method of described Ginger P.E is as follows:Ginger is weighed, after cleaning, drying, is ground into 40 Mesh;The ethanol for adding 10 times of amounts 80% repeats extraction 2 times for extraction solvent, ultrasonic extraction 40-60min, filtering, filter residue, merges Filtrate, ethanol is recovered under reduced pressure to without alcohol taste, obtains Ginger P.E.
Further, the preparation method of described papaya papain is as follows:Fresh papaya is taken, shreds, adds The frozen water for entering 30% is smashed to pieces, filtering, takes filtrate, under conditions of 3500r/min, 4 DEG C, is centrifuged 15min, is taken supernatant, adds Appropriate 0.002mol/L EDTA protector of enzyme activity;80% ethanol of 10 times of amounts is added, is stood overnight, in 5500r/ Under conditions of min, 20min is centrifuged;Filtering, obtains papaya papain.
Further, the preparation method of described cordate houttuynia flavones is as follows:Cordate houttuynia dry powder is weighed, in power 200W, water Position 42mm, under conditions of 55 DEG C of temperature, the ether ultrasonic extraction 30min of 20 times of amounts (g/ml) are added, remove oil-soluble impurities;Water Bath heating removes petroleum ether, adds 10 times of amount (g/ml) 80% ethanol, is boiled in water-bath and control temperature to be carried at 70 DEG C 65min is taken, is filtered, decompression, is filtered while hot after concentration, obtains cordate houttuynia flavones.
Present invention also offers application of the above-mentioned hair remover in cosmetics are prepared, described cosmetics are depilatory cream.
Further, described depilatory cream includes the component of following mass percent:Above-mentioned hair remover 1.6-4.7%, Glycerine 2.6-5.2%, propane diols 3.0-4.12%, isopropyl myristate 1.5-2.7%, caprylic/capric triglyceride 2.1- 3.8%th, poly dimethyl osmanthus oxygen alkane 1.25-3.9%, cetostearyl alcohol 1.12-2.7%, panthenol 6.2-8.7%, allantoin 0.2- 0.7%th, carbomer 0.12-0.27%, methylisothiazolinone 0.002-0.005%, methyl hydroxybenzoate 0.1-0.3%, deionization Water surplus.
Several components in above-mentioned hair remover are introduced below:
Ginger is the rhizome of zingiber.Ginger is widely used in Asia as a kind of time-honored pungent and fragrant flavorings In the cooking of resident's food.Ginger is also a kind of traditional Chinese medicine for being widely used in clinic.Ginger as medicine, first recorded in《God Agriculture book on Chinese herbal medicine warp》,《Mingyi Bielu》Ginger and rhizoma zingiberis slitting are found into name, carry ginger " main cold headache nasal obstruction, cough with dyspnea ".Ginger With clearing heat and detoxicating, sterilization, it is anti-oxidant the effect of, traditional medicine thinks that ginger has a hair regrowth, and 6-gingerol is main in ginger The chemical composition wanted, there is anti-oxidant, removing free radical, suppress prostaglandin synthesis, anticoagulation, inhibition thrombosis, preventing and treating Ten several bioactivity such as angiocardiopathy, antitumor, anti-inflammatory, antiulcer.Ginger P.E 6-gingerol can substantially suppress hair Growth, its mechanism of action may be by increasing MMP-2 in skin histology, and MMP-9m RNA expression quantity suppresses the life of hair It is long.
Papaya originates in tropical America and Africa, Caricaceae, and the traditional Chinese medical science thinks that papaya is sweet, mild-natured, nontoxic, function Nourish, help digestion, desinsection, there is moistening lung, control laryngitis, constipation and bronchitis and other effects.Papaya is containing papain, curdled milk Enzyme, carpaine, human acid-base balance can be adjusted, there is antitumaous effect.Papain has special tender skin effect, it It can discriminatively digest and decompose old skin without injuring new skin, main function mechanism, be by the water to skin keratin albumen Solution acts on and plays the gradual softening of diagonalization skin and dissolve, and promotes the removal of ageing skin cell, accelerates skin and human body Metabolism.The cosmetics that papain and 'alpha '-hydroxy acids, salicylic acid etc. are mixed simultaneously are acted on by molten keratinization, can Cleaning skin, tenderization muscle are produced, eliminate color spot, anti-wrinkle and suppresses the effect of acne produce.Another effect of papain, It is hydrolysis hair keratoprotein, therefore can be used as hair remover, has no side effect to skin.
Cordate houttuynia is Saururaceae heartleaf houttuynia platymiscium, original name " Ji ", first recorded in《Mingyi Bielu》, it is classified as low-grades.Main product in Zhejiang, Jiangsu, Anhui, Fujian, Henan etc. save, and are distributed in Yangtze river basin areas to the south.Its medicinal whole herb with root, property is pungent, and taste is micro- It is cold, enter lung channel.With functions such as the clearing heat and detoxicating, carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia, for lung carbuncle pyemesis, phlegm heat panting cough, heat gonorrhea, heat The diseases such as dysentery, carbuncle sore tumefacting virus, throat acute tonsillitis, hemorrhoid prolapse of the anus.Houttuynia extract can suppress Hair follicle epithelial cells propagation.In cordate houttuynia Flavone compound containing hair growth inhibition, these materials can regulate and control hair growth.
Compared with prior art, it is the device have the advantages that as follows:The present invention is using Ginger P.E, papaya wood Melon protease, cordate houttuynia flavones compounding use in specific proportions, mainly promote hair cell by hydrolyzing hair keratoprotein Removal, while suppress the growth of hair, the effect of cooperative effect is to reach depilation.Wherein, Ginger P.E can substantially suppress The growth of hair, its mechanism of action may be by increasing MMP-2 in skin histology, and MMP-9m RNA expression quantity suppresses hair Growth, also with it is clearing heat and detoxicating, sterilization, it is anti-oxidant the effect of, epifolliculitis can be prevented.Papain passes through to hair cutin The hydrolysis of albumen and play the gradual softening of diagonalization skin and dissolve, promote the removal of hair cell, accelerate hair Metabolism.Cordate houttuynia flavones is by suppressing Hair follicle epithelial cells propagation come hair growth inhibition.Depilatory cream of the present invention is not Only can be with anti-inflammation and sterilization, skin care and Peppermint Extract, additionally it is possible to effective prevention and alleviation epifolliculitis.And preparation method letter of the present invention Single, hair removal effect is good, non-stimulated to skin, have no side effect.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated:
All the components appeared in text are INCI (International Nomenclature Cosmetic Ingredient), i.e., international cosmetic raw material is obviously said to its defined title.
The depilatory cream embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
1. the preparation method of Ginger P.E is as follows:
Ginger is weighed, after cleaning, drying, is ground into 40 mesh;The ethanol for adding 10 times of amounts 80% carries for extraction solvent, ultrasound 40~60min is taken, is filtered, filter residue repeats extraction 2 times, merging filtrate, ethanol is recovered under reduced pressure to without alcohol taste, obtains Ginger P.E.
2. the preparation method of papaya papain is as follows:
Fresh papaya is taken, is shredded, the frozen water for adding 30% smashs to pieces, filters, takes filtrate, in 3500r/min, 4 DEG C Under the conditions of, 15min is centrifuged, supernatant is taken, adds appropriate 0.002mol/L EDTA protector of enzyme activity;10 times of amounts of addition 80% ethanol, stands overnight, and under conditions of 5500r/min, centrifuges 20min;Filtering, obtains papaya papain.
3. the preparation method of cordate houttuynia flavones is as follows:
Cordate houttuynia dry powder is weighed, in power 200W, water level 42mm, under conditions of 55 DEG C of temperature, adds 20 times of amounts (g/ml) Ether ultrasonic extraction 30min, remove oil-soluble impurities;Water-bath heating removes petroleum ether, adds 10 times of amount (g/ml) 80% Ethanol, boiled in water-bath and control temperature at 70 DEG C, extract 65min, filtered, decompression, filtered while hot after concentration, obtain fish raw meat Straw colour ketone.
Comparative example 1:
Ginger P.E is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not Change.
Comparative example 2:
Papaya Papain is not added in difference with embodiment 3 only, remaining each material addition, conditions and technology of preparation Do not change.
Comparative example 3:
Cordate houttuynia flavones is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not Change.
Comparative example 4:
Compared with Example 3, Ginger P.E, papaya Papain, cordate houttuynia flavones do not add, remaining each material Addition, conditions and technology of preparation do not change still.
Product Safety is verified:
Test material:By 1~5 group of above-described embodiment and the depilatory cream of 1~3 group of preparation of comparative example.
Subjects:Cavy 200,250~300g of body weight, and through the culture of the same terms after a while.
Content of the test:
1) mark that size is 2.5cm × 2.5cm is made to cavy of persistence ink;
2) 160 immediate individuals are selected from above-mentioned cavy, are randomly divided into 8 groups, respectively embodiment 1~5 1~3 group of group and comparative example, every group 20, depilatory creams of the 0.5g according to corresponding group formula preparation is smeared respectively at mark, is applied After smearing uniformly, contact site is covered with the gauze of good permeability, applying patch 3h is fixed with bandage;
3) tailend terminate after remove applying patch, cleaned with warm water, dermoreaction observed under natural light after 2 hours.
Result of the test:Influence of each group depilatory cream sample to skin the results are shown in Table 2.
Influence result of the depilatory cream of table 2 to skin
As shown in Table 2, in hair remover of the present invention, each composition does not have after no matter being single use or compounding to organism There are obvious excitant and sensitization, and the abnormal individuals occurred in embodiment are substantially fewer than the individual that comparative example occurs, explanation Hair remover of the present invention obtains by rationally compounding, can optimize its usage experience, reduce stimulation to skin with it is further Allergic manifestation.
Hair removal effect is verified:
Test material:The depilatory cream prepared with 1~5 group of embodiment and the group of formula of comparative example 1~4.
Subjects:Health 90 people of group, health, 20-50 year, men and women half and half;The people of epifolliculitis group 90, with epifolliculitis, 20- 50 years old, men and women half and half.
Content of the test:
1) 9 groups are randomly divided into by healthy group, every group of 10 people, are denoted as 1~4 group of 1~5 group of embodiment and comparative example, apply respectively 0.5g is smeared with depilatory cream prepared by each group of formula in right oxter, after smearing 8min, is cleaned with warm water, compared with left oxter, experienced Person according to service condition to lose hair or feathers, clean and soothing effect evaluate;
2) epifolliculitis group is randomly divided into 9 groups, every group of 10 people, is denoted as 1~4 group of 1~5 group of embodiment and comparative example, respectively The depilatory cream for the depilatory cream preparation that 0.5g is prepared with each group of formula is smeared in right oxter, after smearing 8min, is cleaned with warm water, with a left side Oxter is compared, and experiencer is evaluated anti-inflammatory and epifolliculitis remission effect according to service condition;
3) standards of grading are as follows:100 points of systems, 0 point worst, and 50 points general, and 100 points best, and fraction is the higher the better.
4. result of the test:The aesthetic evaluation result of use of various depilatory creams is shown in Table 3.
The aesthetic evaluation result of use of the depilatory cream of table 3
Known by table 3, depilatory cream prepared by the present invention has not in each side such as depilation, cleaning, anti-inflammatory and alleviation epifolliculitis Wrong effect.
By comparative example 4 and comparative example 1~3 it can be seen that in hair remover of the present invention each composition have certain depilation, cleaning, Anti-inflammatory and alleviation epifolliculitis effect, but effect miss the mark demand.
Meanwhile after embodiment is compounded with composition monomer it can be seen from comparative example that script effect is undesirable, It loses hair or feathers, cleaned, anti-inflammatory and alleviation epifolliculitis effect are substantially improved, and has reached comparatively ideal level, has illustrated hair remover of the present invention Between have synergy, can be acted on by different mechanism, produce complementary effect further improve product efficacy.
Biocidal efficacies are verified
With the depilatory cream made described in embodiment 3, common mixed cell (golden yellow grape in the work of single inoculation cosmetics Coccus SA, Escherichia coli EC, pseudomonas aeruginosa PA), mixed fungus (black-koji mould AN, the false screw mandrel bacterium CA of white), according to change Cosmetic, toilet articles and fragrance association (CTFA) Microbial Challenge test method, sample monitoring cycle are 4 weeks, are during which distinguished Sample detection is carried out the 3rd day and each all last days, calculates the clump count (cfu) per mL.As a result it is as shown in table 4.
Table 4
Strain 0 day 7 days 14 days 21 days 28 days
Mixed cell 2x107 0 0 0 0
Mixed fungus 4x105 0 0 0 0
The result of table 4 shows, with the depilatory cream obtained described in embodiment 3, can effectively suppress the growth of bacterium and fungi, have Good antibacterial and anti-inflammation functions.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention System;It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies Decorations, turn into the equivalent embodiment of equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention With modification, belong in the range of technical solution of the present invention.

Claims (9)

1. a kind of hair remover, it is characterised in that described hair remover includes the component of following mass percent:Ginger P.E 0.1-3.2%, papaya papain 0.2-2.5%, cordate houttuynia flavones 0.15-2.0%.
2. a kind of hair remover according to claim 1, it is characterised in that described hair remover includes following mass percent Component:Ginger P.E 0.25-2.7%, papaya papain 0.3-2.0%, cordate houttuynia flavones 0.3-1.6%.
3. a kind of hair remover according to claim 2, it is characterised in that described hair remover includes following mass percent Component:Ginger P.E 0.5-2.0%, papaya papain 0.5-1.5%, cordate houttuynia flavones 0.6-1.2%.
4. according to the hair remover described in claims any one of 1-3, it is characterised in that the preparation side of described Ginger P.E Method is as follows:Ginger is weighed, after cleaning, drying, is ground into 40 mesh;The ethanol for adding 10 times of amounts 80% carries for extraction solvent, ultrasound 40-60min is taken, is filtered, filter residue repeats extraction 2 times, merging filtrate, ethanol is recovered under reduced pressure to without alcohol taste, obtains Ginger P.E.
5. according to a kind of hair remover described in claims any one of 1-3, it is characterised in that described papaya Papain The preparation method of enzyme is as follows:Fresh papaya is taken, is shredded, the frozen water for adding 30% is smashed to pieces, is filtered, filtrate is taken, in 3500r/ Min, under conditions of 4 DEG C, 15min is centrifuged, supernatant is taken, adds appropriate 0.002mol/L EDTA protector of enzyme activity;Add Enter 80% ethanol of 10 times of amounts, stand overnight, under conditions of 5500r/min, centrifuge 20min;Filtering, obtains papaya pawpaw Protease.
6. according to a kind of hair remover described in claims any one of 1-3, it is characterised in that the system of described cordate houttuynia flavones Preparation Method is as follows:Cordate houttuynia dry powder is weighed, in power 200W, water level 42mm, under conditions of 55 DEG C of temperature, adds 20 times of amount (g/ Ml ether ultrasonic extraction 30min), oil-soluble impurities is removed;Water-bath heating removes petroleum ether, adds 10 times of amounts (g/ml) 80% ethanol, boiled in water-bath and control temperature at 70 DEG C, extract 65min, filtered, decompression, filtered, obtain while hot after concentration Cordate houttuynia flavones.
A kind of 7. application of the hair remover according to claim any one of 1-6 in cosmetics are prepared.
8. application according to claim 7, it is characterised in that described cosmetics are depilatory cream.
9. a kind of depilatory cream containing natural hair remover, it is characterised in that described depilatory cream includes following mass percent Component:Hair remover 1.6-4.7%, glycerine 2.6-5.2%, propane diols 3.0-4.12%, myristic acid as described in right wants 1 is different Propyl ester 1.5-2.7%, caprylic/capric triglyceride 2.1-3.8%, poly dimethyl osmanthus oxygen alkane 1.25-3.9%, cetostearyl alcohol 1.12-2.7%, panthenol 6.2-8.7%, allantoin 0.2-0.7%, carbomer 0.12-0.27%, methylisothiazolinone 0.002-0.005%, methyl hydroxybenzoate 0.1-0.3%, deionized water surplus.
CN201710761775.4A 2017-08-30 2017-08-30 A kind of hair remover and its application Pending CN107362116A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282080A (en) * 2022-08-29 2022-11-04 齐鲁工业大学 Enzyme-containing depilatory preparation
CN117414356A (en) * 2023-11-24 2024-01-19 广州医科大学附属第一医院(广州呼吸中心) Application of 6-gingerol in preparation of products for promoting aging of mastoid cells of hair follicle

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CN105125451A (en) * 2015-10-10 2015-12-09 林彤 Composition capable of inhibiting hair growth and preparation method thereof
CN106620616A (en) * 2016-12-28 2017-05-10 刘志勇 Pharmaceutical composition for preventing hair loss and promoting hair growth and preparation of pharmaceutical composition

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Publication number Priority date Publication date Assignee Title
JPS63303908A (en) * 1987-06-04 1988-12-12 Tsuneo Aranami Cosmetic composition and additive
CN105125451A (en) * 2015-10-10 2015-12-09 林彤 Composition capable of inhibiting hair growth and preparation method thereof
CN106620616A (en) * 2016-12-28 2017-05-10 刘志勇 Pharmaceutical composition for preventing hair loss and promoting hair growth and preparation of pharmaceutical composition

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Title
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陈芬等: "《生物分离与纯化技术》", 31 July 2012, 华中科技大学出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282080A (en) * 2022-08-29 2022-11-04 齐鲁工业大学 Enzyme-containing depilatory preparation
CN117414356A (en) * 2023-11-24 2024-01-19 广州医科大学附属第一医院(广州呼吸中心) Application of 6-gingerol in preparation of products for promoting aging of mastoid cells of hair follicle

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Application publication date: 20171121