CN107362116A - A kind of hair remover and its application - Google Patents
A kind of hair remover and its application Download PDFInfo
- Publication number
- CN107362116A CN107362116A CN201710761775.4A CN201710761775A CN107362116A CN 107362116 A CN107362116 A CN 107362116A CN 201710761775 A CN201710761775 A CN 201710761775A CN 107362116 A CN107362116 A CN 107362116A
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- CN
- China
- Prior art keywords
- hair remover
- ginger
- hair
- cordate houttuynia
- flavones
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/04—Depilatories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a kind of hair remover and its application, the hair remover is made up of the component of following mass percent:Ginger P.E 0.1 3.2%, papaya papain 0.2 2.5%, cordate houttuynia flavones 0.15 2.0%.The hair remover is applied in depilatory cream, not only can be with anti-inflammation and sterilization, skin care and Peppermint Extract, additionally it is possible to effective prevention and alleviation epifolliculitis.And preparation method is simple, hair removal effect is good, non-stimulated to skin, have no side effect.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of hair remover and its application.
Background technology
Beauty in the market is generally divided into three major types on the use of depilatory:Machinery depilation method, chemical defleecing method
With physics depilating method;Wherein, 1, mechanical depilation is to pull out superfluous hairs using the tweezers of most original or razor device is scraped
Division, its is easy to operate, but can not eradicate, and the hair regeneration time is short, and can easily cause hair follicle mistake using the repetition depilation of this method
It is quick, it is unsuitable for large area depilation;2nd, chemical depilation is to be applied to local skin using depilatory cream, depilatory cream, depilation dew etc., is made
Can be corroded, dissolve, being rapidly reached the effect of depilation after hair shaft, and Hair growth rate is slow, sustainable 2 weeks of effect with
On, if but repeatedly, it is long-term use of skin may be caused to damage, or cause chemically, allergic dermatitis, in eye circumference, strength film group
This method can not be used by knitting the region such as around;3rd, physics epilation is lost hair or feathers available for large area, the depilation gimmick commonly used for beauty parlor,
Physics epilation typically uses depilatory cream, and depilatory cream is most original, safest depilatory, is divided into and freezes two kinds of wax and hot wax.
The main component for freezing wax be various kinds of resin, and adherence is strong, water-soluble, jelly, during use does not have to heat, can be directly applied to take off
Skin at hair, and closely adhered with skin, no sense of discomfort, suitable for sensitive part skin depilatory;Hot wax are that beeswax mixes with resin
Conjunction forms, and typically in solid state, needs heating to dissolve before use, when temperature is reduced to suitable skin, can be coated on skin.
It is easy to use to freeze wax, but cost is higher.Hot wax cost is relatively low, and used wax repeats after sterilizing, heat, filter off hair to be made
With, but operate cumbersome, and should skillfully grasp the temperature of wax exactly, the too high easy skin ambustion of temperature, but temperature is relatively low also can
Hair removal effect is influenceed, therefore is typically all used with hot wax depilation in beauty parlor.Moreover, depilatory cream currently on the market is almost required for
Non-woven fabrics is higher as carrier, production cost.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of hair remover, its not only can with anti-inflammation and sterilization,
Skin care and Peppermint Extract, additionally it is possible to effective prevention and alleviation epifolliculitis.And preparation method is simple, hair removal effect is good.
To achieve these goals, the present invention adopts the following technical scheme that:
A kind of hair remover includes the component of following mass percent:Ginger P.E 0.1-3.2%, papaya Papain
Enzyme 0.2-2.5%, cordate houttuynia flavones 0.15-2.0%.
Preferably, described hair remover includes the component of following mass percent:Ginger P.E 0.25-2.7%, kind wood
Melon papain 0.3-2.0%, cordate houttuynia flavones 0.3-1.6%.
Preferably, described hair remover includes the component of following mass percent:Ginger P.E 0.5-2.0%, kind wood
Melon papain 0.5-1.5%, cordate houttuynia flavones 0.6-1.2%.
Further, the preparation method of described Ginger P.E is as follows:Ginger is weighed, after cleaning, drying, is ground into 40
Mesh;The ethanol for adding 10 times of amounts 80% repeats extraction 2 times for extraction solvent, ultrasonic extraction 40-60min, filtering, filter residue, merges
Filtrate, ethanol is recovered under reduced pressure to without alcohol taste, obtains Ginger P.E.
Further, the preparation method of described papaya papain is as follows:Fresh papaya is taken, shreds, adds
The frozen water for entering 30% is smashed to pieces, filtering, takes filtrate, under conditions of 3500r/min, 4 DEG C, is centrifuged 15min, is taken supernatant, adds
Appropriate 0.002mol/L EDTA protector of enzyme activity;80% ethanol of 10 times of amounts is added, is stood overnight, in 5500r/
Under conditions of min, 20min is centrifuged;Filtering, obtains papaya papain.
Further, the preparation method of described cordate houttuynia flavones is as follows:Cordate houttuynia dry powder is weighed, in power 200W, water
Position 42mm, under conditions of 55 DEG C of temperature, the ether ultrasonic extraction 30min of 20 times of amounts (g/ml) are added, remove oil-soluble impurities;Water
Bath heating removes petroleum ether, adds 10 times of amount (g/ml) 80% ethanol, is boiled in water-bath and control temperature to be carried at 70 DEG C
65min is taken, is filtered, decompression, is filtered while hot after concentration, obtains cordate houttuynia flavones.
Present invention also offers application of the above-mentioned hair remover in cosmetics are prepared, described cosmetics are depilatory cream.
Further, described depilatory cream includes the component of following mass percent:Above-mentioned hair remover 1.6-4.7%,
Glycerine 2.6-5.2%, propane diols 3.0-4.12%, isopropyl myristate 1.5-2.7%, caprylic/capric triglyceride 2.1-
3.8%th, poly dimethyl osmanthus oxygen alkane 1.25-3.9%, cetostearyl alcohol 1.12-2.7%, panthenol 6.2-8.7%, allantoin 0.2-
0.7%th, carbomer 0.12-0.27%, methylisothiazolinone 0.002-0.005%, methyl hydroxybenzoate 0.1-0.3%, deionization
Water surplus.
Several components in above-mentioned hair remover are introduced below:
Ginger is the rhizome of zingiber.Ginger is widely used in Asia as a kind of time-honored pungent and fragrant flavorings
In the cooking of resident's food.Ginger is also a kind of traditional Chinese medicine for being widely used in clinic.Ginger as medicine, first recorded in《God
Agriculture book on Chinese herbal medicine warp》,《Mingyi Bielu》Ginger and rhizoma zingiberis slitting are found into name, carry ginger " main cold headache nasal obstruction, cough with dyspnea ".Ginger
With clearing heat and detoxicating, sterilization, it is anti-oxidant the effect of, traditional medicine thinks that ginger has a hair regrowth, and 6-gingerol is main in ginger
The chemical composition wanted, there is anti-oxidant, removing free radical, suppress prostaglandin synthesis, anticoagulation, inhibition thrombosis, preventing and treating
Ten several bioactivity such as angiocardiopathy, antitumor, anti-inflammatory, antiulcer.Ginger P.E 6-gingerol can substantially suppress hair
Growth, its mechanism of action may be by increasing MMP-2 in skin histology, and MMP-9m RNA expression quantity suppresses the life of hair
It is long.
Papaya originates in tropical America and Africa, Caricaceae, and the traditional Chinese medical science thinks that papaya is sweet, mild-natured, nontoxic, function
Nourish, help digestion, desinsection, there is moistening lung, control laryngitis, constipation and bronchitis and other effects.Papaya is containing papain, curdled milk
Enzyme, carpaine, human acid-base balance can be adjusted, there is antitumaous effect.Papain has special tender skin effect, it
It can discriminatively digest and decompose old skin without injuring new skin, main function mechanism, be by the water to skin keratin albumen
Solution acts on and plays the gradual softening of diagonalization skin and dissolve, and promotes the removal of ageing skin cell, accelerates skin and human body
Metabolism.The cosmetics that papain and 'alpha '-hydroxy acids, salicylic acid etc. are mixed simultaneously are acted on by molten keratinization, can
Cleaning skin, tenderization muscle are produced, eliminate color spot, anti-wrinkle and suppresses the effect of acne produce.Another effect of papain,
It is hydrolysis hair keratoprotein, therefore can be used as hair remover, has no side effect to skin.
Cordate houttuynia is Saururaceae heartleaf houttuynia platymiscium, original name " Ji ", first recorded in《Mingyi Bielu》, it is classified as low-grades.Main product in
Zhejiang, Jiangsu, Anhui, Fujian, Henan etc. save, and are distributed in Yangtze river basin areas to the south.Its medicinal whole herb with root, property is pungent, and taste is micro-
It is cold, enter lung channel.With functions such as the clearing heat and detoxicating, carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia, for lung carbuncle pyemesis, phlegm heat panting cough, heat gonorrhea, heat
The diseases such as dysentery, carbuncle sore tumefacting virus, throat acute tonsillitis, hemorrhoid prolapse of the anus.Houttuynia extract can suppress Hair follicle epithelial cells propagation.In cordate houttuynia
Flavone compound containing hair growth inhibition, these materials can regulate and control hair growth.
Compared with prior art, it is the device have the advantages that as follows:The present invention is using Ginger P.E, papaya wood
Melon protease, cordate houttuynia flavones compounding use in specific proportions, mainly promote hair cell by hydrolyzing hair keratoprotein
Removal, while suppress the growth of hair, the effect of cooperative effect is to reach depilation.Wherein, Ginger P.E can substantially suppress
The growth of hair, its mechanism of action may be by increasing MMP-2 in skin histology, and MMP-9m RNA expression quantity suppresses hair
Growth, also with it is clearing heat and detoxicating, sterilization, it is anti-oxidant the effect of, epifolliculitis can be prevented.Papain passes through to hair cutin
The hydrolysis of albumen and play the gradual softening of diagonalization skin and dissolve, promote the removal of hair cell, accelerate hair
Metabolism.Cordate houttuynia flavones is by suppressing Hair follicle epithelial cells propagation come hair growth inhibition.Depilatory cream of the present invention is not
Only can be with anti-inflammation and sterilization, skin care and Peppermint Extract, additionally it is possible to effective prevention and alleviation epifolliculitis.And preparation method letter of the present invention
Single, hair removal effect is good, non-stimulated to skin, have no side effect.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated:
All the components appeared in text are INCI (International Nomenclature Cosmetic
Ingredient), i.e., international cosmetic raw material is obviously said to its defined title.
The depilatory cream embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
1. the preparation method of Ginger P.E is as follows:
Ginger is weighed, after cleaning, drying, is ground into 40 mesh;The ethanol for adding 10 times of amounts 80% carries for extraction solvent, ultrasound
40~60min is taken, is filtered, filter residue repeats extraction 2 times, merging filtrate, ethanol is recovered under reduced pressure to without alcohol taste, obtains Ginger P.E.
2. the preparation method of papaya papain is as follows:
Fresh papaya is taken, is shredded, the frozen water for adding 30% smashs to pieces, filters, takes filtrate, in 3500r/min, 4 DEG C
Under the conditions of, 15min is centrifuged, supernatant is taken, adds appropriate 0.002mol/L EDTA protector of enzyme activity;10 times of amounts of addition
80% ethanol, stands overnight, and under conditions of 5500r/min, centrifuges 20min;Filtering, obtains papaya papain.
3. the preparation method of cordate houttuynia flavones is as follows:
Cordate houttuynia dry powder is weighed, in power 200W, water level 42mm, under conditions of 55 DEG C of temperature, adds 20 times of amounts (g/ml)
Ether ultrasonic extraction 30min, remove oil-soluble impurities;Water-bath heating removes petroleum ether, adds 10 times of amount (g/ml) 80%
Ethanol, boiled in water-bath and control temperature at 70 DEG C, extract 65min, filtered, decompression, filtered while hot after concentration, obtain fish raw meat
Straw colour ketone.
Comparative example 1:
Ginger P.E is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 2:
Papaya Papain is not added in difference with embodiment 3 only, remaining each material addition, conditions and technology of preparation
Do not change.
Comparative example 3:
Cordate houttuynia flavones is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 4:
Compared with Example 3, Ginger P.E, papaya Papain, cordate houttuynia flavones do not add, remaining each material
Addition, conditions and technology of preparation do not change still.
Product Safety is verified:
Test material:By 1~5 group of above-described embodiment and the depilatory cream of 1~3 group of preparation of comparative example.
Subjects:Cavy 200,250~300g of body weight, and through the culture of the same terms after a while.
Content of the test:
1) mark that size is 2.5cm × 2.5cm is made to cavy of persistence ink;
2) 160 immediate individuals are selected from above-mentioned cavy, are randomly divided into 8 groups, respectively embodiment 1~5
1~3 group of group and comparative example, every group 20, depilatory creams of the 0.5g according to corresponding group formula preparation is smeared respectively at mark, is applied
After smearing uniformly, contact site is covered with the gauze of good permeability, applying patch 3h is fixed with bandage;
3) tailend terminate after remove applying patch, cleaned with warm water, dermoreaction observed under natural light after 2 hours.
Result of the test:Influence of each group depilatory cream sample to skin the results are shown in Table 2.
Influence result of the depilatory cream of table 2 to skin
As shown in Table 2, in hair remover of the present invention, each composition does not have after no matter being single use or compounding to organism
There are obvious excitant and sensitization, and the abnormal individuals occurred in embodiment are substantially fewer than the individual that comparative example occurs, explanation
Hair remover of the present invention obtains by rationally compounding, can optimize its usage experience, reduce stimulation to skin with it is further
Allergic manifestation.
Hair removal effect is verified:
Test material:The depilatory cream prepared with 1~5 group of embodiment and the group of formula of comparative example 1~4.
Subjects:Health 90 people of group, health, 20-50 year, men and women half and half;The people of epifolliculitis group 90, with epifolliculitis, 20-
50 years old, men and women half and half.
Content of the test:
1) 9 groups are randomly divided into by healthy group, every group of 10 people, are denoted as 1~4 group of 1~5 group of embodiment and comparative example, apply respectively
0.5g is smeared with depilatory cream prepared by each group of formula in right oxter, after smearing 8min, is cleaned with warm water, compared with left oxter, experienced
Person according to service condition to lose hair or feathers, clean and soothing effect evaluate;
2) epifolliculitis group is randomly divided into 9 groups, every group of 10 people, is denoted as 1~4 group of 1~5 group of embodiment and comparative example, respectively
The depilatory cream for the depilatory cream preparation that 0.5g is prepared with each group of formula is smeared in right oxter, after smearing 8min, is cleaned with warm water, with a left side
Oxter is compared, and experiencer is evaluated anti-inflammatory and epifolliculitis remission effect according to service condition;
3) standards of grading are as follows:100 points of systems, 0 point worst, and 50 points general, and 100 points best, and fraction is the higher the better.
4. result of the test:The aesthetic evaluation result of use of various depilatory creams is shown in Table 3.
The aesthetic evaluation result of use of the depilatory cream of table 3
Known by table 3, depilatory cream prepared by the present invention has not in each side such as depilation, cleaning, anti-inflammatory and alleviation epifolliculitis
Wrong effect.
By comparative example 4 and comparative example 1~3 it can be seen that in hair remover of the present invention each composition have certain depilation, cleaning,
Anti-inflammatory and alleviation epifolliculitis effect, but effect miss the mark demand.
Meanwhile after embodiment is compounded with composition monomer it can be seen from comparative example that script effect is undesirable,
It loses hair or feathers, cleaned, anti-inflammatory and alleviation epifolliculitis effect are substantially improved, and has reached comparatively ideal level, has illustrated hair remover of the present invention
Between have synergy, can be acted on by different mechanism, produce complementary effect further improve product efficacy.
Biocidal efficacies are verified
With the depilatory cream made described in embodiment 3, common mixed cell (golden yellow grape in the work of single inoculation cosmetics
Coccus SA, Escherichia coli EC, pseudomonas aeruginosa PA), mixed fungus (black-koji mould AN, the false screw mandrel bacterium CA of white), according to change
Cosmetic, toilet articles and fragrance association (CTFA) Microbial Challenge test method, sample monitoring cycle are 4 weeks, are during which distinguished
Sample detection is carried out the 3rd day and each all last days, calculates the clump count (cfu) per mL.As a result it is as shown in table 4.
Table 4
Strain | 0 day | 7 days | 14 days | 21 days | 28 days |
Mixed cell | 2x107 | 0 | 0 | 0 | 0 |
Mixed fungus | 4x105 | 0 | 0 | 0 | 0 |
The result of table 4 shows, with the depilatory cream obtained described in embodiment 3, can effectively suppress the growth of bacterium and fungi, have
Good antibacterial and anti-inflammation functions.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention
System;It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies
Decorations, turn into the equivalent embodiment of equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention
With modification, belong in the range of technical solution of the present invention.
Claims (9)
1. a kind of hair remover, it is characterised in that described hair remover includes the component of following mass percent:Ginger P.E
0.1-3.2%, papaya papain 0.2-2.5%, cordate houttuynia flavones 0.15-2.0%.
2. a kind of hair remover according to claim 1, it is characterised in that described hair remover includes following mass percent
Component:Ginger P.E 0.25-2.7%, papaya papain 0.3-2.0%, cordate houttuynia flavones 0.3-1.6%.
3. a kind of hair remover according to claim 2, it is characterised in that described hair remover includes following mass percent
Component:Ginger P.E 0.5-2.0%, papaya papain 0.5-1.5%, cordate houttuynia flavones 0.6-1.2%.
4. according to the hair remover described in claims any one of 1-3, it is characterised in that the preparation side of described Ginger P.E
Method is as follows:Ginger is weighed, after cleaning, drying, is ground into 40 mesh;The ethanol for adding 10 times of amounts 80% carries for extraction solvent, ultrasound
40-60min is taken, is filtered, filter residue repeats extraction 2 times, merging filtrate, ethanol is recovered under reduced pressure to without alcohol taste, obtains Ginger P.E.
5. according to a kind of hair remover described in claims any one of 1-3, it is characterised in that described papaya Papain
The preparation method of enzyme is as follows:Fresh papaya is taken, is shredded, the frozen water for adding 30% is smashed to pieces, is filtered, filtrate is taken, in 3500r/
Min, under conditions of 4 DEG C, 15min is centrifuged, supernatant is taken, adds appropriate 0.002mol/L EDTA protector of enzyme activity;Add
Enter 80% ethanol of 10 times of amounts, stand overnight, under conditions of 5500r/min, centrifuge 20min;Filtering, obtains papaya pawpaw
Protease.
6. according to a kind of hair remover described in claims any one of 1-3, it is characterised in that the system of described cordate houttuynia flavones
Preparation Method is as follows:Cordate houttuynia dry powder is weighed, in power 200W, water level 42mm, under conditions of 55 DEG C of temperature, adds 20 times of amount (g/
Ml ether ultrasonic extraction 30min), oil-soluble impurities is removed;Water-bath heating removes petroleum ether, adds 10 times of amounts (g/ml)
80% ethanol, boiled in water-bath and control temperature at 70 DEG C, extract 65min, filtered, decompression, filtered, obtain while hot after concentration
Cordate houttuynia flavones.
A kind of 7. application of the hair remover according to claim any one of 1-6 in cosmetics are prepared.
8. application according to claim 7, it is characterised in that described cosmetics are depilatory cream.
9. a kind of depilatory cream containing natural hair remover, it is characterised in that described depilatory cream includes following mass percent
Component:Hair remover 1.6-4.7%, glycerine 2.6-5.2%, propane diols 3.0-4.12%, myristic acid as described in right wants 1 is different
Propyl ester 1.5-2.7%, caprylic/capric triglyceride 2.1-3.8%, poly dimethyl osmanthus oxygen alkane 1.25-3.9%, cetostearyl alcohol
1.12-2.7%, panthenol 6.2-8.7%, allantoin 0.2-0.7%, carbomer 0.12-0.27%, methylisothiazolinone
0.002-0.005%, methyl hydroxybenzoate 0.1-0.3%, deionized water surplus.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115282080A (en) * | 2022-08-29 | 2022-11-04 | 齐鲁工业大学 | Enzyme-containing depilatory preparation |
CN117414356A (en) * | 2023-11-24 | 2024-01-19 | 广州医科大学附属第一医院(广州呼吸中心) | Application of 6-gingerol in preparation of products for promoting aging of mastoid cells of hair follicle |
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JPS63303908A (en) * | 1987-06-04 | 1988-12-12 | Tsuneo Aranami | Cosmetic composition and additive |
CN105125451A (en) * | 2015-10-10 | 2015-12-09 | 林彤 | Composition capable of inhibiting hair growth and preparation method thereof |
CN106620616A (en) * | 2016-12-28 | 2017-05-10 | 刘志勇 | Pharmaceutical composition for preventing hair loss and promoting hair growth and preparation of pharmaceutical composition |
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2017
- 2017-08-30 CN CN201710761775.4A patent/CN107362116A/en active Pending
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JPS63303908A (en) * | 1987-06-04 | 1988-12-12 | Tsuneo Aranami | Cosmetic composition and additive |
CN105125451A (en) * | 2015-10-10 | 2015-12-09 | 林彤 | Composition capable of inhibiting hair growth and preparation method thereof |
CN106620616A (en) * | 2016-12-28 | 2017-05-10 | 刘志勇 | Pharmaceutical composition for preventing hair loss and promoting hair growth and preparation of pharmaceutical composition |
Non-Patent Citations (2)
Title |
---|
侯春等: "生姜提取物6-姜酚对毛发生长的影响和机制探讨", 《中国美容医学》 * |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115282080A (en) * | 2022-08-29 | 2022-11-04 | 齐鲁工业大学 | Enzyme-containing depilatory preparation |
CN117414356A (en) * | 2023-11-24 | 2024-01-19 | 广州医科大学附属第一医院(广州呼吸中心) | Application of 6-gingerol in preparation of products for promoting aging of mastoid cells of hair follicle |
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Application publication date: 20171121 |