CN107250112B - 荧光合成类视色素 - Google Patents

荧光合成类视色素 Download PDF

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CN107250112B
CN107250112B CN201580067667.6A CN201580067667A CN107250112B CN 107250112 B CN107250112 B CN 107250112B CN 201580067667 A CN201580067667 A CN 201580067667A CN 107250112 B CN107250112 B CN 107250112B
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compound
formula
stem cells
cells
apoptosis
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CN107250112A (zh
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安德鲁·怀廷
托德·莫德
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High Force Research Ltd
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High Force Research Ltd
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Priority claimed from GB201419496A external-priority patent/GB201419496D0/en
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CN201580067667.6A 2014-10-10 2015-10-09 荧光合成类视色素 Active CN107250112B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1417957.6 2014-10-10
GB201417957A GB201417957D0 (en) 2014-10-10 2014-10-10 Fluorescent synthetic retinoids
GB201419496A GB201419496D0 (en) 2014-10-31 2014-10-31 Fluorescent synthetic retinoids
GB1419496.3 2014-10-31
PCT/GB2015/052956 WO2016055800A2 (en) 2014-10-10 2015-10-09 Fluorescent synthetic retinoids

Publications (2)

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CN107250112A CN107250112A (zh) 2017-10-13
CN107250112B true CN107250112B (zh) 2021-04-23

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US (1) US10759762B2 (enExample)
EP (1) EP3204357B1 (enExample)
JP (1) JP7178781B2 (enExample)
CN (1) CN107250112B (enExample)
AU (2) AU2015329798C1 (enExample)
CA (1) CA2962150C (enExample)
DK (1) DK3204357T3 (enExample)
ES (1) ES2909874T3 (enExample)
PL (1) PL3204357T3 (enExample)
PT (1) PT3204357T (enExample)
SI (1) SI3204357T1 (enExample)
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CN107176945B (zh) * 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用
EP3496711A1 (en) * 2016-08-09 2019-06-19 University Of Durham Synthetic retinoids (in cell modulation)
GB201910239D0 (en) * 2019-07-17 2019-08-28 Lightox Ltd Fluorescent systems for biological imaging and uses thereof
CN115335367B (zh) * 2019-12-19 2024-08-13 奥弗恩制药公司 用于炎性疾病和雄性避孕的RAR-α化合物
CN112479998B (zh) * 2020-11-16 2022-03-15 广州中医药大学(广州中医药研究院) 一种二氢喹啉类荧光探针及其制备方法与应用

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CN1144091A (zh) * 1992-06-11 1997-03-05 阿勒根公司 具有视网膜样活性的化合物
WO1998007716A2 (en) * 1996-08-23 1998-02-26 The Board Of Regents For Oklahoma State University Heteroarotinoids-anticancer agents with receptor specificity and tgase activity
CN101316821A (zh) * 2005-09-30 2008-12-03 詹森药业有限公司 作为rxr激动剂用于治疗异常脂肪血症、高胆固醇血症和糖尿病的二氢-[1h]-喹啉-2-酮衍生物

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US5264578A (en) 1987-03-20 1993-11-23 Allergan, Inc. Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
US4810804A (en) * 1987-03-26 1989-03-07 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
US4980369A (en) 1989-09-19 1990-12-25 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
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