CN107206221B - 微针阵列及使用方法 - Google Patents

微针阵列及使用方法 Download PDF

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Publication number
CN107206221B
CN107206221B CN201680006193.9A CN201680006193A CN107206221B CN 107206221 B CN107206221 B CN 107206221B CN 201680006193 A CN201680006193 A CN 201680006193A CN 107206221 B CN107206221 B CN 107206221B
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China
Prior art keywords
article
microneedle
microneedles
tip
hollow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN201680006193.9A
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English (en)
Chinese (zh)
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CN107206221A (zh
Inventor
迈克尔·J·福瑞茨
克雷格·S·默克林
丹尼尔·H·贝尔格
杰罗姆·E·吉斯伯斯
赖安·帕特里克·西默斯
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3M Innovative Properties Co
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3M Innovative Properties Co
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Publication of CN107206221A publication Critical patent/CN107206221A/zh
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150396—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150404—Specific design of proximal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Optics & Photonics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201680006193.9A 2015-01-21 2016-01-19 微针阵列及使用方法 Expired - Fee Related CN107206221B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562105987P 2015-01-21 2015-01-21
US62/105,987 2015-01-21
PCT/US2016/013820 WO2016118459A1 (en) 2015-01-21 2016-01-19 Microneedle array and method of use

Publications (2)

Publication Number Publication Date
CN107206221A CN107206221A (zh) 2017-09-26
CN107206221B true CN107206221B (zh) 2021-02-09

Family

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Family Applications (1)

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CN201680006193.9A Expired - Fee Related CN107206221B (zh) 2015-01-21 2016-01-19 微针阵列及使用方法

Country Status (9)

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US (1) US10398885B2 (cg-RX-API-DMAC10.html)
EP (1) EP3247449B1 (cg-RX-API-DMAC10.html)
JP (1) JP6909366B2 (cg-RX-API-DMAC10.html)
KR (1) KR102498515B1 (cg-RX-API-DMAC10.html)
CN (1) CN107206221B (cg-RX-API-DMAC10.html)
AU (1) AU2016209496B2 (cg-RX-API-DMAC10.html)
ES (1) ES2885923T3 (cg-RX-API-DMAC10.html)
SG (2) SG11201705981RA (cg-RX-API-DMAC10.html)
WO (1) WO2016118459A1 (cg-RX-API-DMAC10.html)

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CN107126620A (zh) * 2017-06-27 2017-09-05 傅书华 一种隐形注射针
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
KR102188397B1 (ko) * 2018-07-04 2020-12-08 주식회사 지엘캄퍼니 마이크로 니들
KR102186163B1 (ko) 2018-10-08 2020-12-04 연세대학교 산학협력단 다기능 마이크로구조체 패치
CN113939329A (zh) * 2019-06-25 2022-01-14 考司美德制药株式会社 针密度不均匀的微针阵列
JP7689708B2 (ja) * 2019-06-25 2025-06-09 コスメディ製薬株式会社 針密度が不均一なマイクロニードルアレイ
EP4003486A4 (en) * 2019-07-22 2023-12-13 The Trustees of Indiana University Technologies for needles with microchannels
KR102290268B1 (ko) 2019-10-11 2021-08-13 부산대학교 산학협력단 이식형 물질 전달체, 및 이의 제조방법
EP4061334A4 (en) 2019-11-22 2024-02-14 Veradermics Incorporated MICRONEEDLE PATCH FOR THE ADMINISTRATION OF IMMUNO-STIMULATING MEDICATIONS
WO2021221973A1 (en) 2020-04-28 2021-11-04 Ticona Llc Microneedle assembly
KR102742895B1 (ko) * 2020-11-06 2024-12-16 연세대학교 산학협력단 생체 정보 획득 장치 및 이를 이용한 생체 정보 처리 장치
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CN112915378B (zh) * 2021-03-29 2022-07-22 飞诊医疗科技(南通)有限公司 一种智能微针给药器和与智能微针给药器连接的软件
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12029562B2 (en) 2021-04-14 2024-07-09 Satio, Inc. Dermal patch system
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
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US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
CN114129889B (zh) * 2021-11-30 2023-12-19 温州医科大学 一种眼科用环形微针
FR3130167A1 (fr) * 2021-12-10 2023-06-16 Commissariat A L'energie Atomique Et Aux Energies Alternatives Dispositif d'injection/prélèvement d'un fluide à travers la peau d'un être vivant
CN118203752B (zh) * 2023-05-26 2025-10-24 重庆金赛星医疗科技有限公司 空心微针及微针阵列芯片
CN117547725B (zh) * 2023-08-14 2026-07-31 重庆金赛星医疗科技有限公司 可溶性空心微针、微针阵列芯片及经皮给药贴片

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Publication number Publication date
SG11201705981RA (en) 2017-08-30
AU2016209496B2 (en) 2018-06-28
AU2016209496A1 (en) 2017-08-03
KR20170108049A (ko) 2017-09-26
EP3247449B1 (en) 2021-01-06
KR102498515B1 (ko) 2023-02-09
EP3247449A1 (en) 2017-11-29
US10398885B2 (en) 2019-09-03
CN107206221A (zh) 2017-09-26
ES2885923T3 (es) 2021-12-15
JP2018506339A (ja) 2018-03-08
WO2016118459A1 (en) 2016-07-28
SG10201809690VA (en) 2018-12-28
US20180008807A1 (en) 2018-01-11
JP6909366B2 (ja) 2021-07-28

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