CN107184631A - A kind of male capsule in compound sea, preparing process and application method - Google Patents
A kind of male capsule in compound sea, preparing process and application method Download PDFInfo
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- CN107184631A CN107184631A CN201710453209.7A CN201710453209A CN107184631A CN 107184631 A CN107184631 A CN 107184631A CN 201710453209 A CN201710453209 A CN 201710453209A CN 107184631 A CN107184631 A CN 107184631A
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- sea
- cucumber
- capsule
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- oyster
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/616—Echinodermata, e.g. starfish, sea cucumbers or sea urchins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Abstract
A kind of male capsule in compound sea, preparing process and application method, component include sea cucumber, oyster, safflower and the rhizome of davallia, in percentage by weight.Sea cucumber decontamination, cleaning, chopping, drying are dried sea-cucumber by the preparing process of the male capsule in compound sea；Equally by oyster, safflower and rhizome of davallia decontamination, cleaning, drying.The dried sea-cucumber of drying, oyster, safflower, the rhizome of davallia are respectively crushed into fine powder, by weight percentage mixed the fine powder of dried sea-cucumber, oyster, safflower, the rhizome of davallia until uniformly, mixed fine powder is carried out into capsule filling.The compound male capsule in sea is crushed the component of composition using unique ultramicro grinding method, mixing, and the capsule of instant edible is made, with carrying, storage, it is convenient to take the characteristics of；It is to treat osteoporosis, improve the good medicine of body immunity, is adapted to old, children and the patient of dysphagia.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, the more particularly to a kind of male capsule in compound sea, preparing process and user
Method.
Background technology
Osteoporosis (osteoporosis) is one group of osteopathy caused by many reasons, and bone tissue has normal calcification, calcium
Salt is in normal rates with matrix, and the metabolic bone disease with the characteristics of the reduction of unit volume inner bone tissues amount becomes.Dredged in most sclerotin
Song Zhong, caused by the reduction of bone tissue increases mainly due to bone absorption.Morbidity is how slow indivedual very fast, with skeleton pain, is easy to
It is normal that fracture is characterized biochemical analysis.China treatment the loose disease of sclerotin medicine have estrogen, calcitonin, Raloxifene,
Alendronate sodium, risedronate sodium, parathormone Teriparatide etc., they are mostly used to treat women postmenopausal osteoporosis
Disease, and it is not notable to male and other fracture patient curative effects.《Medical and health》Periodical phase in January the 3rd in 238,2016, P167-
5608《Estrogen combinations osteosporosis resistant medicament treats osteoporosis in postmenopausal women》, author is beam subgroup, and this article is mainly
It is oral Caltrate D 600mg/ to introduce the treatment method mentioned in the key agents for the treatment of osteoporosis in postmenopausal women, article
Day once, plus with oral estrogen Raloxifene 60mg/ days once, compared to the control group for not taking estrogen, estrogen is taken
The effect of control group has been obviously improved many.In recent years, with the increase that health, health medicine are publicized, people gradually recognize
To this double-edged sword of chemicals, the harm to human body while disease is treated is also huge, and old friends will wish to entrust to the care of
On green Chinese medicine.The Qing Dynasty《Book on Chinese herbal medicine is with new》Cloud, sea cucumber has the effect of " tonifying kidney and benefiting sperm, yang-tonifying, which is treated, withers ", and《Compendium of Materia Medica is picked up
Lose》Claiming sea cucumber, " kidney tonifying essence, benefiting quintessence, disappear impotence saliva, takes the photograph urine, establishing-Yang, gives birth to hundred arteries and veins.”.Modern study shows that sea cucumber also has and promoted
Enter body cell regeneration and body it is impaired after reparation, the immunologic function of human body can also be improved.At present, the place of sea cucumber medicinal material
Reason method mainly has acid-hydrolysis method, alkali hydrolysis method and proteinase hydrolization method, and modification is hydrolyzed to protein using acid, alkali etc.,
Because the chemical substance property such as soda acid is stronger, the polypeptide of hydrolysis is it is possible that product functionality variation issue, some features
Matter may weaken or lose；The another chemical reagent for participating in chemical reaction it is remaining whether harmful, modified protein can in human body
Absorbed, hydrolysate whether safety, this series of security questions is extremely complex；And it is high using the method producing cost, through acid
Often there is bitter taste in the polypeptide of basic hydrolysis.
The content of the invention
The purpose of the present invention is the defect for overcoming prior art, especially in treatment osteoporosis and raising body immunity
The defect that active drug lacks.According to integration of drinking and medicinal herbs, medicine food invents a kind of preparing process of the male capsule in compound sea with the theory mended
With application method, this method is prepared using four traditional Chinese medicine material, reuses sea cucumber；Using unique ultramicro grinding on preparing process
Method, by four traditional Chinese medicine material respectively through ultramicro grinding into after fine powder, then four traditional Chinese medicine material powder is sufficiently mixed, compound sea is made
Male capsule.This method is in addition to the nutritional ingredient in sea cucumber cooking process is remained, and it takes more convenient, and more conducively patient is living
Institute, taking between mid-term of staying out of going on business.Its drug safety, drug effect clearly, has no toxic side effect.
The technical solution adopted by the present invention：
Using unique ultramicro grinding method on a kind of male capsule in compound sea, preparing process and application method, preparing process, and
Carry out in confined conditions, reduce pollution, retain the drug effect and nutrient of its medicine：The male capsule in compound sea is according to percentage by weight
Prepared, the characteristics of four kinds of medicines of composition are respectively provided with " medicine food is with benefit " and " integration of drinking and medicinal herbs "；Four kinds of medicines through screening enter
Row goes the removal of impurity, cleaning, chopping, drying, and ultramicro grinding into fine powder；Fine powder is mixed with equal increments method, mixed
Filling capsule after uniform, be polished, plastic-aluminum, packaging, finished product.
A kind of component of the male capsule in compound sea includes sea cucumber, oyster, safflower and the rhizome of davallia, in percentage by weight, its
In, sea cucumber 60-70%, oyster 20-30%, safflower 3-8%, rhizome of davallia 3-8%.
A kind of preparing process of the male capsule in compound sea, step is as follows：
(1) it is dried sea-cucumber by sea cucumber decontamination, cleaning, chopping, drying；It is same by oyster, safflower and rhizome of davallia decontamination,
Cleaning, drying；
(2) dried sea-cucumber of drying, oyster, safflower, the rhizome of davallia are respectively crushed into fine powder, crushing process keeps closed
State, crosses 100 mesh sieves standby；
(3) fine powder of dried sea-cucumber, oyster, safflower, the rhizome of davallia is mixed by above-mentioned percentage by weight, mixing is until uniform；
(4) mixed fine powder is subjected to capsule filling, 0.2g/.
A kind of application method of the male capsule in compound sea, step is as follows：
The male capsule in compound sea, orally, one time 4, be within 30 days a course for the treatment of 3 times a day；The high protein such as the flesh of fish, seafood
Autopath disables.
Coordinate " sunbath " cure during taking the male capsule in compound sea, 1-2 hours sunbaths are shone daily, and be aided with fortune
It is dynamic, it is effective to improve fully absorbing for medicine, improve curative effect.
Effect of the described male capsule in compound sea：The strong bone of kidney tonifying, promoting blood circulation and pain relieve promotes knitting；For fracture patient health
Multiple phase and the auxiliary treatment of all kinds of patients with osteoporosis, improve the oral drugs of immune function of human body；
The beneficial effects of the invention are as follows the medicine of the present invention with " integration of drinking and medicinal herbs ", " medicine food is with benefit " is theoretical direction, is prepared
Method is carried out in confined conditions using unique ultramicro grinding method, and the capsule of instant edible is made.Active ingredient dissolution is fast
Fast, absorption is fast, bioavilability is high, with The strong bone of kidney tonifying, promoting blood circulation, effect of promotion knitting；Improve mouthfeel, be conducive to battalion
Support the absorption of material；Content of microorganisms and dust is set just to be controlled.With carry, storage, it is convenient to take the characteristics of, be treatment
The loose disease of sclerotin, the good medicine for improving body immunity, are especially suitable for old, children and the patient of dysphagia.
Embodiment
Describe the specific implementation of the present invention in detail with reference to technical scheme.
The present invention use with " integration of drinking and medicinal herbs ", the male capsule in compound sea is made in four kinds of formulas of " medicine food with mend ", wherein, sea
Ginseng " kidney tonifying essence, benefiting quintessence.Reparation with the regeneration and body for promoting body cell after impaired, can also improve exempting from for human body
Epidemic disease function.The symptom of Osteoarthritis can also be mitigated in clinical practice.Reusing sea cucumber will for monarch.Ministerial drug safflower has promoting blood circulation logical
Through effect of blood stasis removing analgesic；Adjutant oyster, has effects that strong joint, kills perverse trend；The rhizome of davallia is Plants of Polypodiaceae Mongolian oak fern
Rhizome, The strong bone of kidney tonifying, continues and hinders pain relieving；For lumbago due to the kidney deficiency, kidney deficiency chronic diarrhea, Hiccough and deaf, tooth mobility, traumatic injury, muscles and bones
Injured.The combination of four traditional Chinese medicine material increases bone absorption, slows down effect of skeleton pain in side, is clinically used for treatment a variety of causes and draws
The bone loss disorders risen.
Compound method is carried out, taken according to percentage by weight using unique ultramicro grinding method, crushing in confined conditions
Chinese medicine is stated, the Chinese medicine through screening is gone into the removal of impurity, four kinds of medicines is carried out drying and ultramicro grinding respectively, fine powder is used into equivalent
Incremental method is mixed, filling capsule, capsule instant edible after being well mixed.It is polished again, plastic-aluminum, is packaged into finished product.No
Only drug safety has no toxic side effect, and drug effect is significantly, can obviously improve bone density, strengthens cortex of bone.Active ingredient dissolution is fast
Speed, bioavailability is high, carries and take all very convenient, it is adaptable to which the patient of all osteoporosis takes.Improve human body
The good medicine of immunity, is especially suitable for old, children and the patient of dysphagia.
Embodiment 1
According to the constituent and preparing process of the male capsule in compound sea, four kinds of medicines are matched somebody with somebody according to percentage by weight
System, wherein, sea cucumber 65%, oyster 25%, safflower 5%, the rhizome of davallia 5%；Take sea cucumber 130g, oyster 50g, safflower 10g, the rhizome of davallia
10g；
The preparation process of the male capsule in compound sea is：
(1) by fresh sea cucumber decontamination, cleaning is dried after chopping；Equally, by oyster, safflower, rhizome of davallia decontamination,
Cleaning, is dried；
(2) dried sea-cucumber of drying, oyster, safflower, the rhizome of davallia are respectively crushed into fine powder, medicine keeps closed when crushing
State, crosses 100 mesh sieves standby；
(3) fine powder of dried sea-cucumber, oyster, safflower, the rhizome of davallia is mixed by above-mentioned percentage by weight, mixing is until uniform；
(4) mixed fine powder is subjected to capsule filling, 0.2g/；
(5) capsule dispensed is polished, goes outer layer to float powder, carry out aluminum-plastic packaged, progress outsourcing after examining finished product qualified
Dress.
The application method of the male capsule in compound sea
Effect of the male capsule in compound sea：The strong bone of kidney tonifying, promoting blood circulation and pain relieve promotes knitting；For fracture patient convalescence and
The auxiliary treatment of all kinds of patients with osteoporosis, improves the oral drugs of immune function of human body；
Every weight 0.2g of the male capsule in compound sea, orally, one time 4,3 times a day；It is within general 30 days a course for the treatment of；High protein
Autopath disables；
Need to coordinate " sunbath " cure during medication, 1-2 hours sunbaths are shone daily, and be aided with modest movement；Can have
Fully absorbing for the raising medicine of effect, improves curative effect.
Embodiment 2：
A kind of preparing process of the male capsule in compound sea：The medicine is made up of following weight percents：Sea cucumber 60%, oyster
24%th, safflower 8%, the rhizome of davallia 8%, i.e. sea cucumber 60g, oyster 24g, safflower 8g, rhizome of davallia 5g；Preparation process be the same as Example
1 technological process.
Clinical practice and effect：
Our hospital is to accept the large-scale orthopedics and traumatology section hospital based on all kinds of bone fracture illness for medical treatment, and clinical experience shows for many years, sclerotin
Osteoporosis patient adds tonic sea cucumber on basis of conventional therapy and takes Chinese medicine oyster and safflower, can obviously improve bone density,
Strengthen and reuse sea cucumber in cortex, our sides in proportioning for monarch drug in a prescription, ministerial drug safflower has invigorate blood circulation, effect of blood stasis removing analgesic；Assistant
Medicine oyster, has effects that strong joint, kills perverse trend；The rhizome of davallia is the rhizome of Plants of Polypodiaceae Mongolian oak fern, and The strong bone of kidney tonifying, continuous wound is stopped
Bitterly.Four traditional Chinese medicine material increases bone absorption, has effects that to slow down skeleton pain in side, is clinically used for caused by treatment a variety of causes
Bone loss disorders.The male capsule in compound sea studied using our hospital is treated to menopausal women osteoporosis, without taking it
He contains the medicine of estrogen, you can reach good curative effect, and the male capsule in compound sea that our hospital develops can be to each age group
Patients with osteoporosis treated, immunity of organisms can also be improved.The male capsule in compound sea of our hospital's research has medicine food
The characteristics of with mending, its drug effect clearly, has no toxic side effect, and using unique ultramicro grinding method on preparing process, the method is in closing
System is lower to be carried out, and had both avoided micro mist pollution surrounding environment, the dust polluted product in air can be prevented again.With improve mouthfeel,
Be conducive to the absorption of nutriment；The advantages of content of microorganisms and dust are just controlled can be made, can be whole in save medicine
Nutrient, cellulosic also adds water solubility because of miniaturization, and good absorbing, mouthfeel are more preferably.Sunlight is coordinated to replenish the calcium, modest movement can
Reach the effect got twice the result with half the effort.Therefore the dissolution of this product active ingredient is rapid, it is high to absorb fast, bioavilability, makes carrying, storage, clothes
With it is more convenient the features such as will be brought glad tidings to vast sufferers of osteoporosis face.
From in October, 2014 between 2 years October in 2016, the different degrees of sclerotin of our hospital's orthopedics and traumatology outpatient service and 780, ward
Loose patient, man 400, female 380 is age 40-84 Sui, average 62 years old.Take after the male capsule in compound sea 3 months, 6 months, 9
Individual month, 18 months, clap X-ray film, observe bone density and union situation using Dual-energy X-rays absorptionmetry.Measurement parameter is：Just
Often：T- values：- 1SD or more, sclerotin is reduced：T- values:：- 1~-2.5SD, osteoporosis：T- values：Below -2.5SD, seriously
Osteoporosis：T- values：Below -2.5SD.780 sufferers of osteoporosis face T- values of our hospital's income are -1.3~-3.1SD,
Average T- values are -2.2SD.Following table claps X-ray film to take after the male particles capsule in compound sea 3 months, 6 months, 9 months, 18 months
The variable quantity of bone density average value is observed using Dual-energy X-rays absorptionmetry.Improve degree, table 1 to compare osteoporosis symptoms
It is different periods bone density and Symptoms Assessment table after medication.
Table 1
| Period | 3 months | 6 months | 9 months | 18 months |
| Bone density T- value average values | -2.0 | -1.7 | -1.2 | -0.4 |
Shown according to clinical test efficacy result, continuous and long-term taking this product can obviously improve bone density value, and treat
Effect is definite, has no adverse reaction.
Preparation is processed to medicine present invention employs unique ultramicro grinding method, it is possible to decrease pollution, keeps medicine to treat
Nutrient in effect and medicine, dissolution is rapid, and bioavailability is high.Coordinate unique instructions of taking, medicine can be greatly increased
Curative effect, this product carry, it is convenient to take, it is suitable for people of all ages, it is adaptable to which that the patient of all osteoporosis takes.
Claims (4)
1. the male capsule in a kind of compound sea, it is characterised in that the component of the described male capsule in compound sea includes sea cucumber, oyster, safflower
And the rhizome of davallia, in percentage by weight, wherein, sea cucumber 60-70%, oyster 20-30%, safflower 3-8%, rhizome of davallia 3-8%.
2. the preparing process of the male capsule in compound sea described in a kind of claim 1, it is characterised in that step is as follows：
(1) it is dried sea-cucumber by sea cucumber decontamination, cleaning, chopping, drying；Equally, by oyster, safflower and rhizome of davallia decontamination, clear
Wash, dry；
(2) dried sea-cucumber of drying, oyster, safflower, the rhizome of davallia are respectively crushed into fine powder, crushing process keeps closed state, mistake
100 mesh sieves are standby；
(3) fine powder of dried sea-cucumber, oyster, safflower, the rhizome of davallia is mixed by above-mentioned percentage by weight, mixing is until uniform；
(4) mixed fine powder is subjected to capsule filling, 0.2g/.
3. a kind of application method of the male capsule in compound sea described in claim 1, it is characterised in that the male capsule in compound sea, orally,
One time 4, be within 30 days course for the treatment of 3 times a day；High protein autopath disables.
4. application method according to claim 3, it is characterised in that coordinate " sunbath " during taking the male capsule in compound sea
Cure, shines 1-2 hours sunbaths daily, and is aided with motion, effective to improve fully absorbing for medicine, improves curative effect.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710453209.7A CN107184631A (en) | 2017-06-15 | 2017-06-15 | A kind of male capsule in compound sea, preparing process and application method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135284A (en) * | 2019-12-11 | 2020-05-12 | 武汉跃莱健康产业有限公司 | Composition for improving bone mineral density and preparation method and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135284A (en) * | 2019-12-11 | 2020-05-12 | 武汉跃莱健康产业有限公司 | Composition for improving bone mineral density and preparation method and application thereof |
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| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Su Jiquan Inventor after: Su Jiuhui Inventor before: Su Jiquan |
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Application publication date: 20170922 |