CN104324319A - Health-caring product promoting health of bone joint - Google Patents

Health-caring product promoting health of bone joint Download PDF

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Publication number
CN104324319A
CN104324319A CN201410501289.5A CN201410501289A CN104324319A CN 104324319 A CN104324319 A CN 104324319A CN 201410501289 A CN201410501289 A CN 201410501289A CN 104324319 A CN104324319 A CN 104324319A
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parts
health
powder
bone
extract
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李季
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LUOYANG HUAYI BIOTECHNOLOGY Co Ltd
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LUOYANG HUAYI BIOTECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
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  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
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  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention discloses a health-caring product promoting health of bone joints. The health-caring product is composed of bovine bone powder, D-glucosamine potassium sulfate, fermented curcuma powder, a ginseng extract, a cinnamon extract, nicotinic acid, vitamin B12 and folate. In the invention, various drug and diet affinal raw materials are combined so that the health-caring product has effects of boosting bone marrow, reinforcing tendon and strengthening bone, can promote new born and calcification of bones, has curative effects of warming yang and dissipating cold, expelling wind and penetrating bones and the like, is low in cost, is comprehensive in functions and meanwhile is not liable to cause relapse after recovery.

Description

A kind of health product promoting bony articulation health
Technical field
The present invention relates to the field of Chinese medicines, especially a kind of health product promoting bony articulation health.
Background technology
Osteoarthritis is a kind of degenerative disease, and main manifestations is metabolism of articular cartilage and osteoarthrosis structural failure, clinically can occur affected joints pain, swelling, limitation of activity.Can be there is the sings and symptomses such as cartilage peels off, bony spur formation in end-stage patients, cause afunction, even carry out prosthetic replacement's operation time serious.
The Chinese medicine Ma Taishu of existing Singapore import has good curative effect clinically, but its cost is higher, function singleness, pure Chinese medicinal preparation from dispelling exopathogen, start with in strengthening the body resistance two aspect, treatment osteoarthrosis pertinacious disease.
Application number CN102552843A, discloses a kind of pharmaceutical composition for the treatment of osteoarthritis, treats due to stagnation of QI-blood, blockage of main and collateral channels, the pharmaceutical composition of various osteoarthritis caused after adding wind, cold, wet, evil numbness poison intrusion soft tissue and skeleton.This pharmaceutical composition is by Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Cyathulae, the Cortex Eucommiae, Radix Angelicae Sinensis, Radix Clematidis, Rhizoma Et Radix Notopterygii, the Radix Paeoniae Alba, Rhizoma Zingiberis, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Colla cornus cervi, Radix Ginseng, Carapax et Plastrum Testudinis, Olibanum, Myrrha, Flos Carthami etc. by certain weight ratio altogether porphyrize face, mixing and the powder oral medicine of making.Its medication with warming the meridian, cold expelling, blood circulation promoting and blood stasis dispelling, search wind, reduce phlegm inducing menstruation to relieve menalgia, kidney-reinforcing drug is a small amount of, attacks more than benefit, solid basic, recurs common more afterwards.
Summary of the invention
For the cost solving prior art existence is higher, the defect of function singleness and rear easily recurrence, the invention provides a kind of health product promoting bony articulation health, the present invention effectively can treat osteoarthritis, strong osteoarthrosis, strengthens osteotrophy, alleviating pain.
A kind of health product promoting bony articulation health, it is characterized in that: described combination formula according to quality proportioning select into: Os Bovis seu Bubali powder 35 ~ 50 parts, D-glucosamine sulphuric acid potassium salt 25 ~ 35 parts, fermentation curcuma powder 5 ~ 15 parts, Radix Ginseng extract 2.5 ~ 7.5 parts, Cortex Cinnamomi extract 2.5 ~ 7.5 parts, 1.5 ~ 2.5 parts, nicotinic acid, vitamin B12 0.15 ~ 0.30 part, 0.005 ~ 0.015 part, folic acid.
Described best of breed formula according to quality proportioning select into: Os Bovis seu Bubali powder 45 parts, D-glucosamine sulphuric acid potassium salt 30 parts, fermentation curcuma powder 10 parts, Radix Ginseng extract 5 parts, Cortex Cinnamomi extract 5 parts, 2 parts, nicotinic acid, vitamin B12 0.25 part, 0.01 part, folic acid.
Medicine of the present invention has, strong muscle, bone strengthening, can promote that sclerotin is newborn, improve the motility in joint, promote regenerating bone or cartilage, there is warming YANG to expel cold, etc. curative effect, this product also added the high-quality micromolecule Os Bovis seu Bubali cartilage particles that human body easily absorbs simultaneously, directly supplements bone calcium and ossein, fundamentally the nutrition recuperating joint of joint disease crowd, strengthen bone density, strengthening bony articulation health.Its glucosamine, forms the important nutritional labeling of chondrocyte especially, and it has repairs cartilage ligament injury, expedites the emergence of joint lubrication liquid, reduces joint-friction pain, and auxiliary new Chondrogenesis, scavenging free radicals improves the effects such as inflammatory reaction.The modal joint symptoms of joint disease is exactly inflammation, swelling and arthralgia.Rhizoma Curcumae Longae, Cortex Cinnamomi, Radix Ginseng that this product is added all have the effect of warm dispersing cold for relieving pain, and effectively can alleviate arthralgia, the antiinflammatory action of Cortex Cinnamomi Rhizoma Curcumae Longae effectively can also suppress arthritis, reduces inflammatory reaction.
os Bovis seu Bubali powder:secondly have and promote growths, strong skeleton, prevent short and small and cartilage, Os Bovis seu Bubali is nutritious, rich in proteins, fat, and vitamin and the multiple nutritional labeling absorbed for human body such as calcareous, have supplement calcium, defying age, the effects such as raising immunity.Calcareous containing what enrich in Os Bovis seu Bubali, skeleton is grown up beneficial.Meanwhile, collagen protein abundant in Os Bovis seu Bubali, more can promote the absorption of calcium, strong bone density, prevents osteoporosis, has good nutrition recuperating effect to joint disease.The nutritive value of Medulla Bovis seu Bubali is very high, closes fatty acid, have raising immunity of organisms, tonify deficiency labor, effect of benefiting essence-blood containing abundant phospholipid and insatiable hunger.
glucosamine sulfate potassium chloride: glucosamine, being the important nutrient forming chondrocyte, is the natural tissues composition of healthy articular cartilage.Glucosamine has reparation, safeguards cartilage, stimulates chondrocyte growth, expedites the emergence of the effects such as knuckle synovia, be widely used in the auxiliary treatment of joint disease.
fermentation curcuma powder:there is removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia, control all cards of stagnation of QI and blood, born of the same parents' abdomen hypochondriac pain.The traditional Chinese medical science is thought, Rhizoma Curcumae Longae is warm in nature, acrid in the mouth, hardship, has the effect of removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia; Clinical in the twinge of the breast side of body, rheumatism scapulalgia, tumbling and swelling.Curcumin is the main active of Rhizoma Curcumae Longae, and wherein curcumin accounts for again about 70% of curcumin, and Rhizoma Curcumae Longae have the effect of very strong antiinflammatory, antioxidation, scavenging free radicals, has well prevention and mitigation to rheumatoid arthritis.
radix Ginseng extract:radix Ginseng, has the good reputation of " king of BAICAO " since ancient times, is more described as the superfine product of " YIN nourishing is mended raw, strengthening the body resistance " by oriental medicine circle.Radix Ginseng is rich in multiple Saponin and polysaccharide composition, and its fleshy tap root is famous strong tonic.Modern pharmacology research represents, ginsenoside can the immunologic function of enhancing body, and the propagation of Promote immunity cell, to immunoreation all resistant functions of rheumatoid arthritis, has vasorelaxation action simultaneously, can contribute to joint blood circulation passages.
cortex Cinnamomi extract:cortex Cinnamomi is a kind of parts of generic medicinal plants, there is long medicinal history, there is the effects such as dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow, dispelling cold by warming the meridian, replenishing vital QI with drugs of warm nature QI and blood, soreness of the waist and knees, impotence and seminal emission, assistant system be cold and cool, good mitigation can be played to the arthralgia of joint disease.Modern pharmacology effect, Cortex Cinnamomi has antibacterial, antiinflammatory and immuno-recuperative function, has resistant function to the immunoreation of rheumatoid disease.
nicotinic acid:it is relevant with more than 40 kind of biochemical reaction in human body, very important to metabolism.Nicotinic acid has blood vessel dilating, promotes that the effects such as chondrocyte growth are widely used in the auxiliary treatment of joint disease.
vitamin B12:there is treatment and alleviate neuralgia treating, myalgia, arthritis, myelitis, spinal cord degeneration, etc. symptom.
folic acid:have the metabolism promoting juvenile cell maturation in bone marrow, strengthen human body, the effect such as enhancing development and reproductive performance, is widely used in the auxiliary treatment of joint disease.
Beneficial effect of the present invention: the multiple integration of edible and medicinal herbs raw material of compatibility of the present invention, has beneficial bone marrow, strong muscle, bone strengthening, can promote that sclerotin is newborn, bone calcification, has warming YANG to expel cold, searches the curative effects such as wind is deep, and cost is low, and function congruence feature, not easily recurs after recovery from illness simultaneously.
Detailed description of the invention
Embodiment one: described combination formula according to quality proportioning select for: Os Bovis seu Bubali powder 50 parts, D-glucosamine sulphuric acid potassium salt 35 parts, fermentation curcuma powder 15 parts, Radix Ginseng extract 7.5 parts, Cortex Cinnamomi extract 7.5 parts, 2.5 parts, nicotinic acid, vitamin B12 0.30 part, 0.015 part, folic acid, every day 1 ~ 3 time, one time 2 ~ 3 grams.
Embodiment two: described combination formula according to quality proportioning select for: Os Bovis seu Bubali powder 35 parts, D-glucosamine sulphuric acid potassium salt 25 parts, fermentation curcuma powder 5 parts, Radix Ginseng extract 2.5 parts, Cortex Cinnamomi extract 2.5 parts, 1.5 parts, nicotinic acid, vitamin B12 0.15 part, 0.005 part, folic acid, every day 1 ~ 3 time, one time 2 ~ 3 grams.
Embodiment three: described combination formula according to quality proportioning select for: Os Bovis seu Bubali powder 40 parts, D-glucosamine sulphuric acid potassium salt 28 parts, fermentation curcuma powder 4 parts, Radix Ginseng extract 3 parts, Cortex Cinnamomi extract 3.5 parts, 1.5 parts, nicotinic acid, vitamin B12 0.15 part, 0.005 part, folic acid, every day 1 ~ 3 time, one time 2 ~ 3 grams.
case
Wang, female, 72 years old, Chao people from pond, Zhenping County, Nanyang City, Henan Province.In May, 2013 goes to a doctor, and main suit is through examination in hospital waist 3 hyperosteogeny and have bony spur, diathermy after 15 days sensory effect bad, skelalgia, lower limb acid but movable after pain slightly alleviate.Eat pain sheet alleviating pain every day, now consider that patient age thinks expectant treatment.Take medicine of the present invention 4 weeks, pain obviously alleviates, lower limb acid transference cure, and within two months, pain disappears, and adheres to 2 recoveries from illness course for the treatment of of taking medicine, does not recur so far.
Model, man, 35 years old, Wu Ligang people from village, Zhenping County, Henan Province, on August 16th, 2012 goes to a doctor, and the thin and delicate unable one expiration and inspiration 3-4 in two chi pulse Shen is extremely, trouble pelvic bone hypertrophy is sick, and drystone carving lives and bends over ten minutes with regard to pain unbearably, and straight waist has a rest 20 minutes pains gently, whole body sleepiness is unable, and this doctor has joined a course for the treatment of to him, hundred days medicines, take half lumbago light in eight or nine cases out of ten, take pain good, the spring in 2013 joins again a course for the treatment of and consolidates, October pays a return visit, and returns to one's perfect health and stablizes so far.
Lee, man, 46 years old, people from Zhenping County, Nanyang, made a definite diagnosis prolapse of lumbar intervertebral disc disease before 2 years, take the traditional remedies treatments such as traction, massage, acupuncture-moxibustion, symptom is without being clearly better, take medicine of the present invention remission after 5 days, after taking January, waist and lower limb are felt without discomfort, all symptoms completely without, continue to strengthen after treating February, recovery from illness.
Wang, female, 45 years old, people from Nanyang City, Henan Province, in January, 2013 goes to a doctor, main suit: migrans arthralgia more than 20 sky, medical history: private prosecution occurred lumbago without beginning under obvious inducement before more than 20 day, activity more very, after 3 days lumbago alleviate, pain and double knee joint, after be gradually developed to duplex joint, carpal joint and two ankle joint, in migrans, tender joint activity is unfavorable, without stiff phenomenon in obvious morning, time straight backache, cervical pain, limitation of activity of bending over, without uncomfortable in chest, cardiopalmus, in Nanyang, central hospital is diagnosed as rheumatic arthritis.Take medicine of the present invention 2 weeks posterior joint symptoms to take a turn for the better, after continuing to take this medicine March, joint function recovery is normal, does not recur.
The present invention treats above-mentioned disease, and mainly to repair osteoarthrosis, repair joint protecting film, promote regenerating bone or cartilage, strong skeleton is main.Use medicine of the present invention in 2013-2014 years therebetween, once treated 156 people, effective percentage 100%, cure rate 80%, but osteoarthritis is slow with other sick recovery, the time is longer, heals gradually, 1-2 the recovery from illness course for the treatment of.

Claims (2)

1. promote health product for bony articulation health, it is characterized in that Os Bovis seu Bubali powder, D-glucosamine sulphuric acid potassium salt, fermentation curcuma powder, Radix Ginseng extract, Cortex Cinnamomi extract, nicotinic acid, vitamin B12, folic acid, be prepared from according to following weight parts proportioning:
Os Bovis seu Bubali powder 35 ~ 50 parts, D-glucosamine sulphuric acid potassium salt 25 ~ 35 parts, fermentation curcuma powder 5 ~ 15 parts, Radix Ginseng extract 2.5 ~ 7.5 parts, Cortex Cinnamomi extract 2.5 ~ 7.5 parts, 1.5 ~ 2.5 parts, nicotinic acid, vitamin B12 0.15 ~ 0.30 part, 0.005 ~ 0.015 part, folic acid.
2. a kind of health product promoting bony articulation health as described in claim 1, the weight of described raw material is Os Bovis seu Bubali powder 45 parts, D-glucosamine sulphuric acid potassium salt 30 parts, fermentation curcuma powder 10 parts, Radix Ginseng extract 5 parts, Cortex Cinnamomi extract 5 parts, 2 parts, nicotinic acid, vitamin B12 0.25 part, 0.01 part, folic acid.
CN201410501289.5A 2014-09-26 2014-09-26 Health-caring product promoting health of bone joint Pending CN104324319A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107373675A (en) * 2017-07-20 2017-11-24 钟祥亿源生物科技有限公司 One kind protection Bones and joints composition
JP2018203720A (en) * 2017-05-30 2018-12-27 花王株式会社 Bone regeneration agent

Citations (2)

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Publication number Priority date Publication date Assignee Title
CN101401833A (en) * 2008-09-27 2009-04-08 深圳市一德堂医药有限公司 Composition for preventing and/or treating osteoporosis
CN103110744A (en) * 2013-03-20 2013-05-22 吉林华康食元生物科技有限公司 Traditional Chinese medical health-care preparation for increasing bone density and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN101401833A (en) * 2008-09-27 2009-04-08 深圳市一德堂医药有限公司 Composition for preventing and/or treating osteoporosis
CN103110744A (en) * 2013-03-20 2013-05-22 吉林华康食元生物科技有限公司 Traditional Chinese medical health-care preparation for increasing bone density and preparation method thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018203720A (en) * 2017-05-30 2018-12-27 花王株式会社 Bone regeneration agent
EP3632435A4 (en) * 2017-05-30 2021-01-13 Kao Corporation Bone regeneration agent
US10952960B2 (en) 2017-05-30 2021-03-23 Kao Corporation Bone regeneration agent
JP7096069B2 (en) 2017-05-30 2022-07-05 花王株式会社 Bone regeneration agent
CN107373675A (en) * 2017-07-20 2017-11-24 钟祥亿源生物科技有限公司 One kind protection Bones and joints composition

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