CN107158075A - A kind of Chinese medicine for treating canker sore - Google Patents
A kind of Chinese medicine for treating canker sore Download PDFInfo
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- CN107158075A CN107158075A CN201710494003.9A CN201710494003A CN107158075A CN 107158075 A CN107158075 A CN 107158075A CN 201710494003 A CN201710494003 A CN 201710494003A CN 107158075 A CN107158075 A CN 107158075A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：50 60 parts of Sculellaria barbata, 12 18 parts of royal jelly, 42 48 parts of propolis, 17 23 parts of honey, 12 18 parts of honeybee hemolymph.The Chinese medicine for the treatment of canker sore prepared using the formula of the present invention, with instant effect, is had no toxic side effect, can effectively prevent and cure the effect of recurrent oral ulceration.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine for treating canker sore.
Technical background
Canker sore, is a kind of very common disease of cari oris mucosa also known as " aphtha ", some people repeated oral cavity
Ulcer, rises one after another, throughout the year constantly, there is more violent pain, is apt to occur in lip, tongue, gum and side mucous membrane, as " recurrence
Property aphtha ", the patient with RAU is extremely painful.Mainly have from the cause of disease of canker sore in terms of traditional Chinese medical science angle：First, taste
Yun, the strongly fragrant smoked oral cavity of heat and tongue in accumulated heat；2nd, internal heat is flourishing, and heat symptoms caused by an exopathgen are followed through upper inflammation；3rd, it is fire excess from yin deficiency, the ferritic deficiency of Yin or prolonged illness
It is impairment of the kidney, Kidney-Yin loss, YIN-fluid being insufficient, the fire of deficiency type is vigorous, upper scorching oral cavity.Modern medicine then thinks that canker sore belongs to vitamin B2Lack
The sign of disease, bacterium infection or whole body system disease and other immunity diseases in mucous membrane of mouth.At present for canker sore
Treatment have multi-medicament, such as Bingpeng San, antibioticses antiphlogistic, Bingpeng San is the most frequently used, but therapeutic effect is not very managed
Think, and antibiotic antiphlogistic is particularly for the people that repeated canker sore to many toxic side effects of human body, long-term taking
Antibioticses antiphlogistic, it is possible to decline immunity of organisms, so that recovery from illness is more difficult to, regardless of whether being that Bingpeng San or antibiotic disappear
Scorching medicine is all simply temporary transient to be healed at ulcer, does not cure canker sore fundamentally, while can not also prevent oral cavity to burst
The generation of ulcer.
The content of the invention
The purpose of the present invention be that for solve the deficiencies in the prior art provide a kind of instant effect, have no toxic side effect, energy
Effectively prevent and cure a kind of Chinese medicine of recurrent oral ulceration.
The purpose of the present invention is realized with following technical proposals：
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：50-60 parts of Sculellaria barbata, queen bee
12-18 parts of slurry, 42-48 parts of propolis, 17-23 parts of honey, 12-18 parts of honeybee hemolymph.
A kind of above-mentioned Chinese medicine for treating canker sore, wherein, it is prepared from by the raw material of following parts by weight：Sculellaria barbata 55
Part, 15 parts of royal jelly, 45 parts of propolis, 20 parts of honey, 15 parts of honeybee hemolymph.
The preparation method of above-mentioned treatment canker sore Chinese medicine, comprises the following steps：
（1）Prepare Sculellaria barbata immersion liquid；
（2）Prepare propolis liquid；
（3）By royal jelly, honey, honeybee hemolymph and step（2）In the propolis liquid and step prepared（1）In prepare half
The immersion liquid of branch lotus is well mixed, and is produced.
The preparation method of above-mentioned treatment canker sore Chinese medicine, wherein, step（1）Prepare Sculellaria barbata immersion liquid specifically include as
Lower step：The Sculellaria barbata of above-mentioned parts by weight is weighed, after the water immersion 20-30min for adding 10-15 times of raw material weight, big fire is decocted,
After water boiling 10-20min, 20-30min is cooked by slow fire, decoction is filtered out, Sculellaria barbata immersion liquid is produced.
The preparation method of above-mentioned treatment canker sore Chinese medicine, wherein, step（2）Prepare propolis liquid and specifically include following step
Suddenly：The propolis of above-mentioned parts by weight is weighed, is filtered after adding the ethanol water of 20-25 times of raw material weight, immersion 10-12h, heating
Filtrate removes second alcohol and water, produces propolis liquid.
The preparation method of above-mentioned treatment canker sore Chinese medicine, wherein, the mass fraction of the ethanol water is 70-
90%。
In inventive formulation, sun plant is cold in nature sour, and herb contains the compositions such as multivitamin, trace element and amino acid,
There is the effect of removing pattogenic heat from the blood and toxic material from the body, blood stasis removing analgesic, detumescence and clearing heat and promoting diuresis, with clearing heat and detoxicating, promoting blood circulation, swelling and pain relieving, anticancer
Etc. function；Not only contain several amino acids, vitamin, hormone, enzyme and various bioactivators in royal jelly, also contain
10- hydroxyl -2- certain herbaceous plants with big flowers olefin(e) acids, with stronger bactericidal action；Its is mild-natured for honey, bitter, pungent, micro-sweet, can not containing a variety of human bodies
Or scarce trace element, there is moisturizing myogenic, effect of anti-inflammatory analgetic can treat gastric ulcer, canker sore, burn and scald, fissure of skin
Bitterly, the illness such as radiation proof；The bioactive substance unique containing abundant in propolis, with antibacterial, anti-inflammatory is antipruritic, anti-oxidant,
Enhancing is immune, hypoglycemic, reducing blood lipid, the effects such as antitumor, and qi-restoratives for oral administration is weak, changes turbid fat, only quenches one's thirst, external application removing toxicity for detumescence；Honey
Honeybee hemolymph is one of constituent main in honeybee body, accounts for the 25%-30% of honeybee body weight, plays transport substance in vivo, battalion
Support and humoral immunity effect, hemolymph is the blood sample liquid being present in honeybee open cycle system, in water white transparency state,
There is the characteristic of blood and liquid of haemolymph simultaneously, main function is the materials such as transport nutrition, ion and hormone, its content point blood
There are the inorganic ions such as sodium, potassium, calcium, magnesium, free amino acid, malic acid, citrate, amber in slurry and haemocyte two parts, blood plasma
The organic acids such as amber hydrochlorate and lipid, enzyme, antibacterial peptide, hormone etc., haemocyte includes hematogone, and plasmatocytes, particle is thin
Born of the same parents, oenocytoid, ball haemocyte, the class of blood platelet six is immunity of organism defense function important component, wherein antibacterial peptide
, can quick killing target with broad spectrum antibiotic activity.Wherein, honeybee hemolymph is from honeybee belly 3-4 sections in the present invention
Between backboard, insert a capillary to obtain.
In above-mentioned raw materials, Sculellaria barbata being capable of removing pattogenic heat from the blood and toxic material from the body, blood stasis removing analgesic, detumescence；Royal jelly, honey, propolis, honeybee blood strangury
Bar is respectively provided with sterilization, and anti-inflammatory, analgesic, the antibacterial that effect of moisturizing myogenic, particularly propolis and honeybee hemolymph have wide spectrum is lived
Property, can not only rapid recovery patient pain, while can also realize anti-infectious purpose, in addition, Sculellaria barbata, queen bee
Contain multivitamin and nutriment in slurry, honey, propolis, honeybee hemolymph, and honeybee hemolymph has transportation battalion
The effect of the material such as foster, ion and hormone, promotes the absorption of ulcer spot and human body to vitamin and nutriment, improves
The immunity of human body.Moreover, the raw material used in inventive formulation has no toxic side effect, the Chinese medicine prepared both can be direct
Ulcer spot is contacted, ulcer spot is healed rapidly, resistivity is then strengthened, greatly by the Chinese medicine of the oral present invention again
The recurrence of canker sore is reduced, equally can also be in canker sore suffering season, the Chinese medicine in the oral present invention, enhancing resistance energy
Power, the generation of anti-treating dental ulcer.
Embodiment
Embodiment 1
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：50-60 parts of Sculellaria barbata, royal jelly
12-18 parts, 42-48 parts of propolis, 17-23 parts of honey, 12-18 parts of honeybee hemolymph.
The preparation method of the Chinese medicine of above-mentioned treatment canker sore, comprises the following steps：
（1）The Sculellaria barbata of above-mentioned parts by weight is weighed, after the water immersion 20-30min for adding 10-15 times of raw material weight, big fire is decocted,
After water boiling 10-20min, 20-30min is cooked by slow fire, decoction is filtered out, Sculellaria barbata immersion liquid is prepared；
（2）The propolis of above-mentioned parts by weight is weighed, the mass fraction of 20-25 times of raw material weight is added water-soluble for 70-90% ethanol
Filtered after liquid, immersion 10-12h, heating filtrate removes second alcohol and water, prepares propolis liquid；
（3）By the royal jelly of above-mentioned parts by weight, honey, honeybee hemolymph and step（2）In the propolis liquid and step prepared（1）
In the Sculellaria barbata immersion liquid prepared be well mixed, produce.
In use, above-mentioned Chinese medicine can first be wrapped into an osculum is contained in affected part 10min in mouth, then oral 150mL, sooner or later daily
Respectively once, wait and continue to take above-mentioned Chinese medicine 3-7 days after ulcer healing.
Embodiment 2
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：55 parts of Sculellaria barbata, royal jelly 15
Part, 45 parts of propolis, 20 parts of honey, 15 parts of honeybee hemolymph.
The preparation method of the Chinese medicine of above-mentioned treatment canker sore, comprises the following steps：
（1）The Sculellaria barbata of above-mentioned parts by weight is weighed, after the water immersion 25min for adding 12 times of raw material weights, big fire is decocted, water boiling
After 15min, 25min is cooked by slow fire, decoction is filtered out, Sculellaria barbata immersion liquid is prepared；
（2）The propolis of above-mentioned parts by weight is weighed, mistake after the mass fraction ethanol water of 22 times of raw material weights, immersion 11h is added
Filter, heating filtrate removes second alcohol and water, prepares propolis liquid；
（3）By the royal jelly of above-mentioned parts by weight, honey, honeybee hemolymph and step（2）In the propolis liquid and step prepared（1）
In the Sculellaria barbata immersion liquid prepared be well mixed, produce.
The Chinese medicine for the treatment canker sore prepared using said ratio and method, with instant effect, have no toxic side effect, energy
Effectively prevention and the effect of healing recurrent oral ulceration.
Embodiment 3
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：53 parts of Sculellaria barbata, royal jelly 16
Part, 44 parts of propolis, 17 parts of honey, 12 parts of honeybee hemolymph.Specific preparation method be the same as Example 2.
The Chinese medicine for the treatment canker sore prepared using said ratio and method, with instant effect, have no toxic side effect, energy
Effectively prevention and the effect of healing recurrent oral ulceration.
Comparative example 1
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：55 parts of Sculellaria barbata, royal jelly 15
Part, 45 parts of propolis, 20 parts of honey.Specific preparation method be the same as Example 2.Compared with Example 2, it is not added with honeybee hemolymph.Adopt
The Chinese medicine prepared with said ratio and method, there is certain curative effect to treatment canker sore, but it is relatively slow, it is necessary to continuous to take effect
The canker sore of patient could for a long time be cured by taking.
Comparative example 2
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：55 parts of Sculellaria barbata, royal jelly 15
Part, 20 parts of honey, 15 parts of honeybee hemolymph.Specific preparation method be the same as Example 2.Compared with Example 2, it is not added with propolis.Adopt
The Chinese medicine prepared with said ratio and method, has certain curative effect for the patient of lighter canker sore, but for mouth
Chamber ulcer more serious patient, especially Blood of Patients with Recurrent Oral weak curative effect, slowly effect, and easily recurrence, because this
A little patient bodies are weak, and immunity is poor.
Comparative example 3
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：55 parts of Sculellaria barbata, royal jelly 15
Part, 45 parts of propolis, 15 parts of honeybee hemolymph.Specific preparation method be the same as Example 2.Compared with Example 2, it is not added with honey.Adopt
The Chinese medicine prepared with said ratio and method, ulcer healing is slower, also has certain injury to the taste of patient.
Comparative example 4
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：55 parts of Sculellaria barbata, 45 parts of propolis,
20 parts of honey, 15 parts of honeybee hemolymph.Specific preparation method be the same as Example 2.Compared with Example 2, it is not added with royal jelly.Using
The Chinese medicine that said ratio and method are prepared, it is more notable to slight canker sore patient curative effect, but for recurrent mouthful
Chamber ulcers curative effect is poor.
Comparative example 5
A kind of Chinese medicine for treating canker sore, it is prepared from by the raw material of following parts by weight：15 parts of royal jelly, 45 parts of propolis,
20 parts of honey, 15 parts of honeybee hemolymph.Specific preparation method be the same as Example 2.Compared with Example 2, it is not added with Sculellaria barbata.Using
The Chinese medicine that said ratio and method are prepared, to slight canker sore patient's instant effect, but suffers to serious canker sore
Inefficacy for person, and for canker sore patient, be not suitable for long-term consumption, preferably get angry.
The formula of the Chinese medicine for the treatment canker sore that 4-18 of the embodiment of the present invention is provided is shown in Table 1-2.
Table 1
Table 2
Clinical report
Chinese medicine of the present invention suffered from 100 patients of canker sore in clinical observation in 2011 to 2015, and clinical report is as follows：
1st, general information
In 100 patients, age 15-75 Sui, average age 40 years old.Wherein, slight canker sore patient 10, recurrent oral
Ulcers 90.The symptom of Blood of Patients with Recurrent Oral mainly has Behcet's disease, and oral mucosa lesion ulcer is herpetic
Stomatitis, erythema multiforme, contact stomatitis, necrotic gingivostomatitis and malignant ulcer etc..
2nd, diagnostic criteria
The symptom of Blood of Patients with Recurrent Oral mainly has Behcet's disease, oral mucosa lesion ulcer, herpetic stomatits, multiform
Property erythema, contact stomatitis, necrotic gingivostomatitis and malignant ulcer etc..
3rd, criterion of therapeutical effect
Clinical cure：Clinical symptoms are wholly absent, and drug withdrawal is not recurred in two years；
Effectively：Clinical symptoms are wholly absent, and drug withdrawal has recurrence in two years；
It is invalid：Clinical symptoms are not improved or aggravated.
4th, treatment method
The Chinese medicine for the treatment canker sore prepared in embodiment 2 is taken, specific instructions of taking is by above-mentioned Chinese medicine elder generation Bao Yi little
The affected part 10min in mouth is sucked, then oral 150mL, once in the morning and once at night, wait and continue to take above-mentioned Chinese medicine after ulcer healing
3-7 days.
5th, result：10 slight canker sore patients, take two days ulcer healings, and continuously take 3 days, thoroughly cure.
90 Blood of Patients with Recurrent Oral, take ulcer healing after 5-7 days, and continuously take 7 days, cure 81 people（Cure rate 90%）,
Effective 9 people（Effective percentage 10%）, invalid 0 people（Inefficiency 0%）.
Model case
Case one：26 years old, canker sore often occurs inside lip for Zhu, female, and sleep can always be waken up by pain when serious,
The medicines of a variety for the treatment of canker sore were taken, but every time after ulcer healing, can be recurred again in a few days, intermittently three
After year, the Chinese medicine that canker sore is treated in the present embodiment 2 ulcer surface healing after one week is taken, continues to stop after taking five days again
Medicine, follow-up 2 years is again without recurrence.
Case two：The Qin, man, 36 years old, oral mucosa contrafluxion, redness had pain, take in the present embodiment 2 and control
Two days later, symptom is wholly absent the Chinese medicine for the treatment of canker sore, is continued to take three days again and is consolidated.
Case three：Dai, female, 55 years old, the raw sore of dispute many places erosion, it is swollen that sore is flushing, and scorching hot pain takes the present embodiment 2
The Chinese medicine of middle treatment canker sore is after four days, and symptom is wholly absent, and is continued to take five days again and is consolidated, and 2 years nothings of follow-up are multiple
Hair.
Claims (6)
1. a kind of Chinese medicine for treating canker sore, it is characterised in that be prepared from by the raw material of following parts by weight：Sculellaria barbata 50-
60 parts, 12-18 parts of royal jelly, 42-48 parts of propolis, 17-23 parts of honey, 12-18 parts of honeybee hemolymph.
2. a kind of Chinese medicine for treating canker sore as claimed in claim 1, it is characterised in that by the raw material system of following parts by weight
It is standby to form：55 parts of Sculellaria barbata, 15 parts of royal jelly, 45 parts of propolis, 20 parts of honey, 15 parts of honeybee hemolymph.
3. the preparation method of the treatment canker sore Chinese medicine as described in claim any one of 1-2, it is characterised in that including following
Step：
（1）Prepare Sculellaria barbata immersion liquid；
（2）Prepare propolis liquid；
（3）By royal jelly, honey, honeybee hemolymph and step（2）In the propolis liquid and step prepared（1）In prepare half
The immersion liquid of branch lotus is well mixed, and is produced.
4. the preparation method of canker sore Chinese medicine is treated as claimed in claim 3, it is characterised in that step（1）Prepare half
Lotus immersion liquid specifically includes following steps：The Sculellaria barbata of above-mentioned parts by weight is weighed, the water immersion 20- of 10-15 times of raw material weight is added
After 30min, big fire is decocted, and after water boiling 10-20min, is cooked by slow fire 20-30min, is filtered out decoction, produce Sculellaria barbata immersion liquid.
5. the preparation method of canker sore Chinese medicine is treated as claimed in claim 3, it is characterised in that step（2）Prepare propolis
Liquid specifically includes following steps：The propolis of above-mentioned parts by weight is weighed, the ethanol water of 20-25 times of raw material weight, immersion is added
Filtered after 10-12h, heating filtrate removes second alcohol and water, produces propolis liquid.
6. the preparation method of canker sore Chinese medicine is treated as claimed in claim 5, it is characterised in that the ethanol water
Mass fraction is 70-90%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710494003.9A CN107158075A (en) | 2017-06-26 | 2017-06-26 | A kind of Chinese medicine for treating canker sore |
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| CN201710494003.9A CN107158075A (en) | 2017-06-26 | 2017-06-26 | A kind of Chinese medicine for treating canker sore |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579702A (en) * | 2012-03-14 | 2012-07-18 | 山东赛克赛斯药业科技有限公司 | Medicine for treating dental ulcer and preparation method thereof |
| CN104997831A (en) * | 2015-07-08 | 2015-10-28 | 山东省立医院 | Oral spray and preparation method thereof |
-
2017
- 2017-06-26 CN CN201710494003.9A patent/CN107158075A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579702A (en) * | 2012-03-14 | 2012-07-18 | 山东赛克赛斯药业科技有限公司 | Medicine for treating dental ulcer and preparation method thereof |
| CN104997831A (en) * | 2015-07-08 | 2015-10-28 | 山东省立医院 | Oral spray and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 上海市中医文献馆编: "《内科难病(九)》", 31 December 2012, 中国中医药出版社 * |
| 杨书琴主编: "《蜂胶•花粉•冬虫夏草祛百病》", 30 September 2016, 上海科学技术出版社 * |
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Application publication date: 20170915 |