CN107095961A - A kind of instant particles as Chinese medicine and preparation method for being used to treat adolescent acne - Google Patents

A kind of instant particles as Chinese medicine and preparation method for being used to treat adolescent acne Download PDF

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CN107095961A
CN107095961A CN201710490015.4A CN201710490015A CN107095961A CN 107095961 A CN107095961 A CN 107095961A CN 201710490015 A CN201710490015 A CN 201710490015A CN 107095961 A CN107095961 A CN 107095961A
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parts
root
blood
herb
chinese medicine
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邵竹蕾
王冬萍
刘萍
隋盛楠
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Abstract

The invention discloses a kind of instant particles as Chinese medicine and preparation method for being used to treat adolescent acne, belong to the field of Chinese medicines.The raw material of effective ingredient of the present invention is constituted:The public rattan of Herba portulacae, the root of straight ladybell, horse hail, emblic leafflower root, duck, korean pine seed, fringed pink, japanese white birch bark, blumea, garden burnet, the fruit of summer cypress, the Fructus Sophorae, pectinate rungia herb, radix polygonati officinalis, nepal fleshspike herb, grass of meadow rue, Ligusticum wallichii, linseed, radix glycyrrhizae, China rose, Chinese violet, golden cypress, indian mockstrawberry root, rheum officinale.The present invention meets a monarch and his subjects left side from medicinal material and is allowed to manage, suited the remedy to the case for the cause of disease, there are clearing heat-fire, detoxicating and resolving a mass, healing up sore and subduing swelling, cooling blood and dissolving stasis, nourishing the blood to expel wind, moist skin, good absorbing effect, it is evident in efficacy, have no toxic side effect and clinical adverse, it is higher to adolescent acne cure rate according to clinical verification.

Description

A kind of instant particles as Chinese medicine and preparation method for being used to treat adolescent acne
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of instant particles as Chinese medicine and preparation side for being used to treat adolescent acne Method..
Background technology
Adolescent acne is a kind of a kind of relatively conventional disease for being apt to occur in face and chest and back.It is apt to occur in puberty man Female, in papulosquamous, is often accompanied by seborrhea, therefore be commonly called as " whelk " after extruding.Adolescent acne is more common in face, also occurs Behind thoracic dorsal top and omoplate, front, neck, buttocks etc., and adolescent acne is often not disappear for a long time, and old wound is not cured, newly Disease is sent out.Adolescent acne is pityriasis rubra papule to the basic lesions of skin, shows as blackhead and Whiteheads;If generation is scorching Disease, acne are rubescent, and papilla just occurs in top, at this moment will produce influence to appearance, great psychology is caused to young man Pressure and mental suffering.
The cause of disease of acne is complex, wherein, endocrine factors, infective agent, dietary factor etc. are in the morbidity of acne Play an important role.This disease of western medical treatment suit the medicine to the illness generally according to symptom, respectively give XCJF cream, Kezuo Yintong Cream, Benzoyl peroxide emulsifiable paste, Fusidic Acid Cream, Tretinoin emulsifiable paste, isotretinoin ointment, salicylic acid gel, tazarotene cream, The doctors trained in Western medicine such as adapalene gel often carry out external application for curing with externally applied drug, and with certain curative effect, quick result, but doctor trained in Western medicine Zhi Biao is not Effect a permanent cure, easy recurrent exerbation.
The traditional Chinese medical science then thinks that young Yang Re is contained partially, then because wind and heat in the lung meridian poison is evil stifling, stomach and intestine are damp and hot, follows through upper heap soil or fertilizer over and around the roots chest, outside Sense poison is evil, and heat toxin accumulates poly- skin, and blood is transported not smooth, stagnation of blood stasis, or disharmony of Chong and Conception Channels, the not smooth qi and blood stasis of menses and formed.Heat, Malicious, the wet, stasis of blood is the Etiological interpretation of the cause, onset and process of an illness of acne formation.Therefore this disease of Chinese traditional treatment dispels inducement by nursing one's health in vivo, and curative effect shows Write, uneasy to recur, Small side effects, but the Chinese traditional treatment course for the treatment of is long, it is necessary to which long-term treatment can just see effect.Therefore this is treated Disease uses therapy of combing traditional Chinese and Western medicine, treats both principal and secondary aspect of disease, instant effect, and good effect is uneasy to recur.
Chinese medicine of the present invention is formed through long-term clinical practice configuration, is suited the remedy to the case according to the cause of disease, is dissipated with clearing heat-fire, removing toxic substances The effect of knot, healing up sore and subduing swelling, cooling blood and dissolving stasis, nourishing the blood to expel wind, moist skin, set about from internal conditioning, clearing lung-heat heat, irascibility of dispelling, clearly Stomach is damp and hot, leads to intestine and small intestine, removes hot gas in skin, dissipates malignant sore, and skin of moistening, dissipation skin chronic inflammation excludes vivotoxin, Recover incretion balance, then with the use of Western medicine external application rapid osmotic, treat both principal and secondary aspect of disease, comprehensively solve adolescent acne and acne scar Infringement problem of the trace to skin, good absorbing effect is evident in efficacy, has no toxic side effect and clinical adverse, uneasy to recur, through facing Bed checking is higher to adolescent acne cure rate.
The content of the invention
Be used to treat the instant particles as Chinese medicine and preparation method of adolescent acne the invention provides a kind of, with clearing heat-fire, The effect of detoxicating and resolving a mass, healing up sore and subduing swelling, cooling blood and dissolving stasis, nourishing the blood to expel wind, moist skin, cure the disease and ask source to treat both principal and secondary aspect of disease, to various originals The adolescent acne caused by is respectively provided with good curative effect.
To achieve the above object, technical scheme is implemented as follows:
A kind of instant particles as Chinese medicine for being used to treat adolescent acne, is made the raw material composition and parts by weight of the effective ingredient For:
30~60 parts of Herba portulacae, 20~30 parts of the root of straight ladybell, 15~30 parts of horse hail, 15~30 parts of emblic leafflower root,
15~30 parts of rattan of duck public affairs, 10~30 parts of korean pine seed, 10~30 parts of fringed pink, 10~30 parts of japanese white birch bark
10~30 parts of blumea, 10~25 parts of garden burnet, 10~25 parts of the fruit of summer cypress, 10~25 parts of the Fructus Sophorae,
9~15 parts of pectinate rungia herb, 9~15 parts of radix polygonati officinalis, 9~15 parts of nepal fleshspike herb, 6~15 parts of grass of meadow rue,
6~15 parts of Ligusticum wallichii, 6~12 parts of linseed, 6~12 parts of radix glycyrrhizae, 6~12 parts of China rose,
3~9 parts of Chinese violet, 3~9 parts of golden cypress, 3~6 parts of indian mockstrawberry root, 1~5 part of rheum officinale.
Be made the effective ingredient raw material composition and parts by weight be:
40 parts of Herba portulacae, 25 parts of the root of straight ladybell, 25 parts of horse hail, 20 parts of emblic leafflower root,
20 parts of rattan of duck public affairs, 20 parts of korean pine seed, 15 parts of fringed pink, 15 parts of japanese white birch bark
15 parts of blumea, 15 parts of garden burnet, 12 parts of the fruit of summer cypress, 12 parts of the Fructus Sophorae,
12 parts of pectinate rungia herb, 12 parts of radix polygonati officinalis, 12 parts of nepal fleshspike herb, 12 parts of grass of meadow rue,
10 parts of Ligusticum wallichii, 10 parts of linseed, 9 parts of radix glycyrrhizae, 9 parts of China rose,
6 parts of Chinese violet, 6 parts of golden cypress, 4 parts of indian mockstrawberry root, 2 parts of rheum officinale.
A kind of preparation method for being used to treat the instant particles as Chinese medicine of adolescent acne, is comprised the following steps that:
(1)By Herba portulacae, the root of straight ladybell, horse hail, emblic leafflower root, the public rattan of duck, korean pine seed, fringed pink, japanese white birch bark, blumea, garden burnet, summer cypress Son, the Fructus Sophorae, pectinate rungia herb, radix polygonati officinalis, nepal fleshspike herb, grass of meadow rue, linseed, China rose, Chinese violet, indian mockstrawberry root, rheum officinale, which are cleaned, to be dried After be well mixed, be put into container, in a reservoir add 6~8 times amount water, heating boil 2~3 hours, immersion liquid is taken after cooling; The water of 4~6 times of amounts is added in the remaining dregs of a decoction, heating is boiled 1~2 hour, and immersion liquid is taken after cooling;Merge gained twice to soak Liquid, heating is concentrated by evaporation as the thick paste of relative density 1.15~1.25, standby;
(2)Take the sprinkling of Ligusticum wallichii piece yellow rice wine uniform, slightly vexed, it is degree to micro- Jiao to put stir-fry in pot, and taking-up is cooled, and crushing is ground, and crosses 100 Mesh dusting cover, obtains fine powder, standby;
(3)Net licorice tablet is taken, cooked honey and a little boiling water is added, it is slightly vexed after mixing thoroughly, put in frying container, slow fire is fried to depth Yellow, is taken out when tack-free, cools, and crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby;
(4)Golden cypress piece is taken, is sprayed with salt solution, is mixed thoroughly, the micro- stir-fry of the interior slow fire of pot is put, taking-up is cooled, dried, and crushing is ground, and crosses 100 Mesh dusting cover, obtains fine powder, standby;
(5)By step(1)The thick paste of gained, with step(2), step(3), step(4)The fine powder mixing of middle gained, plus auxiliary material sugarcane Sugar and dextrin, which are well mixed, is made particle, after dry, whole grain, is packaged into every bag of 8g instant particles as Chinese medicine.
The property of medicine of Chinese medicine used of the invention is as follows:
Herba portulacae:It is pungent;Acid;It is cold in nature;It is nontoxic.Enter large intestine, liver, the spleen channel.It is clearing heat and detoxicating;Cooling blood and hemostasis;Dissipate blood detumescence.Cure mainly sore Ulcer carbuncle furuncle;Scrofula;Warm tinea.《Tang materia medica》Carry:" main all swollen fistula wart mesh." modern medicine finds that purslane has higher nutriture value Value and medical value, in addition to containing nutrients such as conventional proteins,vitamins,and mineralses, purslane is also containing uniqueness Bioactive ingredients, the activity of Human Epithelial Cells can be strengthened, help lend some impetus to ulcer and healing, be particularly suitable for use in inflammation Disease skin, can be effectively increased the oxidation resistance of Skin Cell, and reduce inflammation symptom.
The root of straight ladybell:It is sweet;Slight bitter;Cold nature.Return lung;Stomach.Replenishing the vital essence and removing heat;Moistening lung for removing phlegm;Reinforcing stomach reg fluid.Cure mainly the deficiency of Yin long Cough;Consumptive disease is coughed phlegm blood;Cough caused by dryness phlegm is few;Abnormal heat larynx numbness;Injury thirst.《Compendium of Materia Medica》Carry:" the root of straight ladybell is sweet light and cold, and its body is gently empty, specially Tonifying lung gas, thus beneficial spleen and kidney, thus gold can by fiery gram person preferably it.Yang-tonifying and give birth to the moon, tonifying yin and sun processed must be debated." existing Confirmed for medical research, the root of straight ladybell contains volatile oil, cumarin, starch, alkaloid, triterpenic acid, stigmasterol, β-each sterol, improve T Cell ratio, improves lymphocyte transformation rate, and increasing leukocyte strengthens macrophage function, extends antibody existence time, there is solution Heat, analgesia, eliminating the phlegm, function of relievining asthma, enhancing body fluid and cell immunologic function, to irritability and medicine gastric ulcer have protection and Inhibitory action.
Horse hail:It is sweet;It is bitter;It is cool in nature.Return lung;Liver;The spleen channel.It is clearing heat and detoxicating;Dispersing swelling and dissipating binds;Resolving sputum diuresis.Cure mainly ulcerative carbuncle Furuncle;Subcutaneous nodule scrofula;Abscess of throat;Mumps;Urolithiasis;Difficult urination;Skin eczema;Hot eyes jaundice;Hemorrhoid complicated by anal fistula;Prolapse of the anus;Wound goes out Blood;Venomous snake bite.Guangzhou army《Conventional Chinese herbal medicine handbook》:Detumescence and drawing out poison, eliminating phlegm dissipating bond, clearing liver Li Shui.Control ulcerative carbuncle furuncle, skin Skin eczema, abscess of throat, parotitis, urinary tract infections, calculus, acute conjunctivitis, infantile malnutrition.
Emblic leafflower root:It is sweet;Slight bitter;It is cool in nature.Return liver;The spleen channel.Clearing heat and promoting diuresis;Detoxicating and resolving a mass.Cure mainly diarrhea;Dysentery;Jaundice; Scrofula;Skin eczema;Centipde-bite.《The south of the Five Ridges is gathered medicinal herbs record》:It is clearing heat and detoxicating.
Duck public affairs rattan:It is sweet;It is bitter;It is cool in nature.Clearing heat and promoting diuresis;Detoxicating and resolving a mass.Cure mainly cough with lung heat;Lung carbuncle;Jaundice with damp-heat pathogen;Heat Drench;Dysentery;Under band;Lymphnoditis;Ulcer furuncle.
Korean pine seed:It is sweet;Slightly warm in nature.Return liver;Lung;Large intestine channel.Moisturize, blood-nourishing, wind-dispelling.Dryness of the lung dry cough is cured mainly, stool is empty Secret, all public attention are dizzy, joint wind, wandering arthritis.And have moist skin, apply Rong Maofa function.《Japan hanako materia medica》:By wandering arthritis cold air, Empty thin few gas, tonifying for the deficiency moistens skin, fertile the five internal organs.
Fringed pink:Bitter;It is cold in nature.Enter the heart;Liver;Small intestine;Bladder warp.Diuresis;Clearing away damp-heat;Invigorate blood circulation.Cure mainly urine not It is logical;Heat gonorrhea;Blood strangury;Amenorrhoea;Red eye, swell pain;Carbuncle sore tumefacting virus;Wet sore itch.《Book on Chinese herbal medicine is just》Carry:" property slides profit, can diuresis, drop the moon Fire, except five pouring, sharp blood vessels.All all diseases of damp-heat in lower-JIAO pain, can all use it." modern medicine study shows, fringed pink have diuresis, The effect of antibacterial, desinsection, anti peroxidation of lipid, is also acted on suppression cardiac muscle, expansion blood vessel, decompression and excited intestinal tube etc..
Japanese white birch bark:Bitter;It is mild-natured.Return lung;Stomach;Large intestine channel.Clearing heat and promoting diuresis, expelling phlegm and arresting coughing, subdhing swelling and detoxicating.Control pneumonia, dysentery Disease, diarrhoea, jaundice, ephritis, urinary tract infections, chronic bronchitis, acute tonsillitis, periodontitis, acute mastitis, furuncle is itched Rash, is scalded.《Bencao Jingshu》:" japanese white birch bark, five subcutaneous ulcers all it is damp and hot accumulate Yu Yangming caused by, hardship is flat can be except damp and hot, therefore leads all subcutaneous ulcers.Hide Row heat toxin sore when device controls typhoid fever with it, ancestor's Seok controls lung wind toxin with it, all takes its bitter cool energy to dissipate the justice ear of ailment said due to cold or exposure heat toxin." modern times doctor Learning research has shown that:Japanese white birch bark has cough-relieving, eliminating the phlegm, relieving asthma and antibacterial effect.
Blumea:Bitter;It is cold in nature.Clearing heat-fire;Removing toxicity for detumescence.Cure mainly cough with lung heat;Abscess of throat;Aphthae;Stomach Pyretic toothache;Zha ribs;Carbuncle sore tumefacting virus.《Yunnan Chinese herbal medicine》:It is clearing heat and detoxicating, anti-inflammatory.Control infantile pneumonia, tonsillitis, parotitis, mouth Chamber is scorching, nameless sores or boils, pruitus.
Garden burnet:Bitter;Acid;It is cold in nature, it is nontoxic.Enter liver;Lung;Kidney;Large intestine channel.Cooling blood and hemostasis;It is clearing heat and detoxicating;Healing up sore and subduing swelling. Cure mainly haematemesis;Spitting of blood;Bleeding from five sense organs or subcutaneous tissue;Hematuria;Have blood in stool;Hemorrhoid blood;Bloody flux;Uterine bleeding;Leukorrhea with reddish discharge;Sore, carbuncle and painful swelling;Eczema;Pruritus vulvae;Extreme misery Scald and burn;Snake bite and insect sting.《Do not record》Carry:" only purulence blood, all impotences, malignant sore, disappear wine, except quenching one's thirst, and mends wound absolutely, is filled in postpartum, can make metal-inflicted wound Cream, main interior leakage is more than, and blood is not enough." modern medicine study confirms that garden burnet contains a large amount of tannins, there is stronger convergence, can shrink Blood vessel, reduces the permeability of blood vessel, reduces inflammatory and oozes out, while also obvious bactericidal action, can resist charrin's disease.
The fruit of summer cypress:Bitter;It is cold in nature.Return kidney;Bladder warp.Clearing heat and promoting diuresis;Dispelling wind and arresting itching.Cure mainly difficult urination;Stranguria with turbid discharge;Band Under;Bloody flux;Rubella;Eczema;Mange;Pruitus;Sore.《Do not record》:Hot gas in skin is removed, malignant sore is dissipated, hernia lump in the abdomen, Qiang Yin makes People moistens.Modern medicine study is proved:Fruit of summer cypress flooding agent has effect that is antibacterial and suppressing allergy.
The Fructus Sophorae:Bitter;It is cold in nature.Cooling blood and hemostasis;Clear liver and improve vision.Cure mainly hemorrhoid hemorrhage;Discharging fresh blood stool;Bloody flux;Uterine bleeding;Blood Drench;Blood-head tells nosebleed;The hot hot eyes of liver;Have a dizzy spell.《This warp》:Perverse trend heat in main five, only saliva and spittle, mends wound, five hemorrhoid, fiery sore, woman absolutely Human milk disease, sub- Tibetan shoot.Modern medicine study is proved:Contain a large amount of rutins in the Fructus Sophorae, rutin has antiinflammatory action, with maintenance blood Pipe resistance, reduces its permeability, reduces the effect such as fragility, fat effect of being dispelled to the liver of fatty infiltration.Also antiviral and suppression The effect of aldose reductase processed.
Pectinate rungia herb:Mildly bitter flavor;It is pungent;It is cool in nature.Return lung;Liver;The spleen channel.Disperse accumulations is stagnant;Purge the green;Clearing away damp-heat.Cure mainly infantile indigestion with food retention; Red eye, swell pain;Damp-heat dysentery;Hepatitis;Scrofula carbuncle swells;Venomous snake bite.《Conventional Chinese herbal medicine handbook》:Calming liver and clearing heat, consumer product dredge stasis. Children's indigestion is controlled, is lost the appetite, hepatitis, acute combination film is scorching, is caught a cold, laryngalgia, lymphoid tuberculosis, furuncle.
Radix polygonati officinalis:It is sweet;It is mild-natured.Return lung;Stomach.Nourishing Yin and moistening lung;Nourishing the stomach to improve the production of body fluid.Cure mainly cough caused by dryness;Overstrain cough;Pyreticosis yin-fluid consumption wound Dry throat and mouth;Heat Diabetes;Deficiency of Yin diseases caused by external factors;Dizzy dizziness;Tendon and vessel contraction pain.《This warp》:" main apoplexy sudden-heat, it is impossible to shake, fall Muscle knot meat, various symptims and signs of deficiency.Long term usage goes to the black open country in face, and good color is moistened." modern medicine study confirms, radix polygonati officinalis have the calm nerve of nourishing and The effect sprained is got injured by a fall in the effect of cardiac stimulant, also hypoglycemic effect, and moist skin, dissipation skin chronic inflammation and treatment.
Nepal fleshspike herb:Bitter;It is sweet;Cold nature.Return lung;Liver Channel.The flat liver of heat-clearing;Eliminating damp, detoxifying.Cure mainly cough with lung heat;The head is dizzy It is dizzy;Tinnitus;It is deaf;Day red photophobia;Hepatitis;Arthralgia pain due to rheumatism;Bruise wound is swollen;Snake-head furuncle;Nameless sores or boils.《Traditional Chinese Medicine in Sichuan will》:Clearly Lung heat, irascibility of dispelling controls arthralgia pain due to rheumatism, tinnitus, deafness and mesh mist photophobia.
Grass of meadow rue:Bitter;It is cold in nature.The thoughts of returning home;Liver;Large intestine channel.Clearing heat-fire;Eliminating dampness is detoxified.Cure mainly Vexed;It is damp and hot to rush down Dysentery;Cough with lung heat;Red eye, swell pain;Carbuncle swells boil.
Ligusticum wallichii:It is pungent;It is warm-natured.Return liver;Courage;Pericardium channel.Promoting blood circulation;Promote breath and open depression;Wind-expelling pain-stopping.Zhu Zhi wei lump in the abdomen swells Block;Pain in chest and hypochondrium;Dizziness of having a headache;Wind-cold-dampness arthralgia;Traumatic injury;Ulcer sores.《Book on Chinese herbal medicine is just》Carry:" dispersing wind and cold controls pain, broken stasis of blood Store, promoting blood circulation, unhitch gas, by pain, apocenosis detumescence is stimulated the menstrual flow by blood." modern medical science research discovery, Ligusticum wallichii extract solution pair Suppressing leukaemia has certain effect, and preparation has certain antibacterial action, especially to typhoid bacillus, paratyphosum Bacterium, suddenly Random vibrios, Pseudomonas aeruginosa and pathogenic dermatophyte etc. have inhibitory action, and the ligustrazine, forulic acid contained by Ligusticum wallichii are received with work Blood stagnation resolvation effect, expansible coronary artery promotes coronary flow, allevating angina pectoris, and has anti-thrombosis function, contained Ligustilide has smooth muscle spasmolysis and suppresses the effect such as myenteron, uterine contractile.
Linseed:It is sweet;It is mild-natured.Return liver;Stomach;Large intestine channel.Nourishing the blood to expel wind;Moistening dryness for relaxing bowels.Cure mainly leprosy;Dry skin; Itch;Alopecia;Sore eczema;Dry constipation of intestines.《Chinese medicine handbook》:Logical intestine and small intestine, removing toxic substances analgesic.Control intestines heat, erysipelas.
Radix glycyrrhizae:It is sweet;It is mild-natured.The thoughts of returning home;Lung;Spleen;Stomach.Invigorate the spleen and benefit qi;It is clearing heat and detoxicating;Expelling phlegm and arresting coughing;Relieving spasm to stop pain;Adjust With all medicines.Cure mainly weakness of the spleen and the stomach;Lassitude hypodynamia;Palpitation;Coughing with a lot of sputum;Gastral cavity abdomen four limbs contraction;Carbuncle sore tumefacting virus;Alleviate Drug toxicity.《Compendium of Materia Medica》Carry:" radix glycyrrhizae is monarch in all medicines.72 kinds of mammary calculus poison are controlled, draft is malicious by every means for solution 1,002, adjusts With it is active from medicine." modern medicine study confirms that radix glycyrrhizae has a stronger detoxication, also antiulcer, anti-inflammatory, antispastic antibechic, Lowering blood pressure and blood fat, antitumaous effect, are widely used in treatment sphagitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis Etc. disease, additionally acted on anti-gastric-ulcer, gastritis.
China rose:It is sweet;It is warm-natured;It is nontoxic.Return liver;Kidney channel.Promoting blood circulation for regulating menstruation;Removing toxicity for detumescence.Cure mainly irregular menstruation;Dysmenorrhoea; Amenorrhoea;Traumatic injury;Blood stasis and swelling pain;Scrofula;Carbuncle swells;Scald.《Quanzhou book on Chinese herbal medicine》:Restore menstrual flow and invigorate blood circulation stagnation resolvation, and gut purge stomach are damp and hot, purging the lung of pathogenic fire Fire, cough-relieving, hemostasis and pain-relieving, the carbuncle that disappears poison.Cough due to deficiency of the lung's spitting of blood is controlled, dysentery, scrofula is festered, swollen ulcer drug, menoxenia.
Chinese violet:Bitter;It is pungent;It is cold in nature.The thoughts of returning home;Liver Channel.It is clearing heat and detoxicating;Cool blood detumescence.Cure mainly jaundice, dysentery, mammary gland Inflammation, red eye, swell pain, pharyngitis, traumatic injury, carbuncle swells, furuncle swelling toxin, ulcer carbuncle on the back, erysipelas, venomous snake bite.《This is through meeting original》Carry: " the swollen malignant sore of malignant boil is controlled, and treats ulcer carbuncle on the back, nameless sores or boils." modern medicine study confirmation, Chinese violet, which in vitro has, to be suppressed to tie The effect of core bacillus growth, its alcohol extract has inhibitory action to Leptospira, has inhibitory action to trichophyton, in addition still There is the effect such as heat-clearing, detumescence, anti-inflammatory.
Golden cypress:Bitter;It is cold in nature.Enter kidney;Bladder warp.Heat-clearing and damp-drying drug;Purging intense heat and detonicating.Cure mainly damp-heat dysentery, diarrhea, jaundice; Under nocturnal emission, stranguria with turbid discharge, band;Hectic fever due to yin labor heat;And aphthae;Red eye, swell pain;Skin sore;Skin eczema.《Medicineization justice》Carry: " fall fire can capit ad calcem, and the thorough marrow of the skin that falls invariably thoughtfully, specially rushes down the fire of kidney and bladder." modern medicine study confirmation, golden cypress is containing small The main components such as tiller alkali, obakunone, have antibacterial, convergence, anti-inflammatory, antibechic, decompression, anti-trichomonal, anti-hepatitis, antiulcer and enhancing to exempt from The effect of epidemic disease function, to symptoms such as various skin wet poisons, sores, effect is good.
Indian mockstrawberry root:It is bitter, sweet;It is cold in nature.Return lung;Liver;Stomach.Clearing heat-fire;Removing toxicity for detumescence.Cure mainly pyreticosis, water infantile convulsion, Red eyes swollen, mumps, swelling and aching of gum, abscess of throat, pathopyretic ulcer.
Rheum officinale:Bitter;It is cold in nature.Enter stomach;Large intestine;Liver;The spleen channel.Attack stagnant;Clearing away damp-heat;Purging intense heat;Cool blood;Dissolving stasis;Removing toxic substances.It is main Control real heat constipation;The thermojunction feeling of stuffiness in chest;Damp-heat dysentery;Jaundice;Gonorrhoea;Oedema abdomen is expired;Difficult urination;Hot eyes;Abscess of throat;Dispute is given birth to Sore;Gastropyretic vomiting;Spit blood;Spitting of blood;Bleeding from five sense organs or subcutaneous tissue;Have blood in stool;Hematuria;Store blood;Amenorrhea;Postpartum stasis of blood;Wei lump in the abdomen is gathered;Bruise is damaged Wound;Heat toxin large carbuncle;Erysipelas;Scald.《Japan hanako materia medica》Carry:" it is logical to declare all gas, blood vessels are adjusted, the stagnant, aqueous vapor of heap soil or fertilizer over and around the roots, four are rushed down in sharp joint Limb unbalanced cold and heat, the warm hot phlegm of miasma, sharp stool and urine, and apply all boil carbuncles poison." modern medicine study confirms that rheum officinale has wide spectrum Antiviral, antibacterial and antimycotic effect, available for the preventing and treating of various inflammation, the active ingredient of rheum officinale can eliminate oxygen radical, Anti-lipid peroxidation, with anti-aging effects, additionally with prominent regulation immunologic function, has very to disease in the urological system Obvious prevention and therapeutic action.
The present invention compared with prior art, has the advantages that:
The present invention from medicinal material monarch, minister, a left side, make all reasons all standby, the property of medicine is mutually fitted mutually auxiliary, is suited the remedy to the case for the cause of disease, has heat-clearing to rush down The effect of fire, detoxicating and resolving a mass, healing up sore and subduing swelling, cooling blood and dissolving stasis, nourishing the blood to expel wind, moist skin, good absorbing effect is evident in efficacy, nothing Toxic side effect and clinical adverse are higher to adolescent acne cure rate according to clinical verification.
Embodiment
The present invention is further elaborated with reference to specific embodiment.
Embodiment 1
The raw material of effective ingredient of the present invention is constituted and weight is:
30~60 parts of Herba portulacae, 20~30 parts of the root of straight ladybell, 15~30 parts of horse hail, 15~30 parts of emblic leafflower root,
15~30 parts of rattan of duck public affairs, 10~30 parts of korean pine seed, 10~30 parts of fringed pink, 10~30 parts of japanese white birch bark
10~30 parts of blumea, 10~25 parts of garden burnet, 10~25 parts of the fruit of summer cypress, 10~25 parts of the Fructus Sophorae,
9~15 parts of pectinate rungia herb, 9~15 parts of radix polygonati officinalis, 9~15 parts of nepal fleshspike herb, 6~15 parts of grass of meadow rue,
6~15 parts of Ligusticum wallichii, 6~12 parts of linseed, 6~12 parts of radix glycyrrhizae, 6~12 parts of China rose,
3~9 parts of Chinese violet, 3~9 parts of golden cypress, 3~6 parts of indian mockstrawberry root, 1~5 part of rheum officinale.
The processing step of process for preparing medicine of the present invention is:
(1)By Herba portulacae, the root of straight ladybell, horse hail, emblic leafflower root, the public rattan of duck, korean pine seed, fringed pink, japanese white birch bark, blumea, garden burnet, summer cypress Son, the Fructus Sophorae, pectinate rungia herb, radix polygonati officinalis, nepal fleshspike herb, grass of meadow rue, linseed, China rose, Chinese violet, indian mockstrawberry root, rheum officinale, which are cleaned, to be dried After be well mixed, be put into container, in a reservoir add 6~8 times amount water, heating boil 2~3 hours, immersion liquid is taken after cooling; The water of 4~6 times of amounts is added in the remaining dregs of a decoction, heating is boiled 1~2 hour, and immersion liquid is taken after cooling;Merge gained twice to soak Liquid, heating is concentrated by evaporation as the thick paste of relative density 1.15~1.25, standby;
(2)Take the sprinkling of Ligusticum wallichii piece yellow rice wine uniform, slightly vexed, it is degree to micro- Jiao to put stir-fry in pot, and taking-up is cooled, and crushing is ground, and crosses 100 Mesh dusting cover, obtains fine powder, standby;
(3)Net licorice tablet is taken, cooked honey and a little boiling water is added, it is slightly vexed after mixing thoroughly, put in frying container, slow fire is fried to depth Yellow, is taken out when tack-free, cools, and crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby;
(4)Golden cypress piece is taken, is sprayed with salt solution, is mixed thoroughly, the micro- stir-fry of the interior slow fire of pot is put, taking-up is cooled, dried, and crushing is ground, and crosses 100 Mesh dusting cover, obtains fine powder, standby;
(5)By step(1)The thick paste of gained, with step(2), step(3), step(4)The fine powder mixing of middle gained, plus auxiliary material sugarcane Sugar and dextrin, which are well mixed, is made particle, after dry, whole grain, is packaged into every bag of 8g instant particles as Chinese medicine.
Usage and dosage:2 times a day 1 bag every time, morning and evening sub-service, before meals half an hour taken after mixing it with water with boiling water, be within 10 days 1 course for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention is constituted and weight is:
40 parts of Herba portulacae, 25 parts of the root of straight ladybell, 25 parts of horse hail, 20 parts of emblic leafflower root,
20 parts of rattan of duck public affairs, 20 parts of korean pine seed, 15 parts of fringed pink, 15 parts of japanese white birch bark
15 parts of blumea, 15 parts of garden burnet, 12 parts of the fruit of summer cypress, 12 parts of the Fructus Sophorae,
12 parts of pectinate rungia herb, 12 parts of radix polygonati officinalis, 12 parts of nepal fleshspike herb, 12 parts of grass of meadow rue,
10 parts of Ligusticum wallichii, 10 parts of linseed, 9 parts of radix glycyrrhizae, 9 parts of China rose,
6 parts of Chinese violet, 6 parts of golden cypress, 4 parts of indian mockstrawberry root, 2 parts of rheum officinale.
The process for preparing medicine processing step and usage and dosage of the present embodiment are same as Example 1.
Clinical data:
1st, case selection
68 clinical observations of adolescent acne patient that selection our hospital makes a definite diagnosis, patient is randomly divided into two groups.Treatment group 34, wherein Male 23, women 11,15~24 years old age, average age 17.8 years old.Control group 34, wherein male 24, women 10 Example, 14~24 years old age, average age 18.1 years old.
All patients are healthy, closely over the past half year without any treatment.Clinical manifestation:For face acne, papule, tubercle, capsule A variety of combination infringements such as swollen, abscess and scar, minority is also simultaneous to be sent out in chest and back.Two groups of qualifications and record of service are basically identical, without significantly Difference, with comparativity.
2nd, treatment group patient takes Chinese medicine of the present invention orally, and gives doctor trained in Western medicine local topical medicine progress external application for curing, treatment 1 to the ill ~3 courses for the treatment of.
Control group is suited the medicine to the illness give XCJF cream, kecuocryptone respectively according to the classification for the adolescent acne being diagnosed to be Emulsifiable paste, benzoyl peroxide emulsifiable paste, Fusidic Acid Cream, Tretinoin emulsifiable paste, isotretinoin ointment, salicylic acid gel, tazarotene The doctors trained in Western medicine such as emulsifiable paste, adapalene gel often carry out external application for curing with external used medicine.
3rd, efficacy determination:
(1)Cure:Skin damaged all disappears, and only leaves pigmentation spots, and subjective symptoms disappears;
(2)Take a turn for the better:Skin damaged regression more than 40%, subjective symptoms is clearly better
(3)It is invalid:Skin damaged regression less than 40%, subjective symptoms is unchanged, occurs with new skin damaged.
4th, result
Treatment group's cure rate 63.3%, total effective rate 93.3%, control group cure rate 43.3%, total effective rate 83.3%, two groups of treatments Effect compares, and difference has statistical significance(P<0.05), therefore treatment group is substantially better than control group for this sick curative effect.
1 two groups of patient clinical comparitive studies of table
Model case is illustrated:
1st, neat ××, man, 17 years old.The patient face and nose give birth to acne 2 months, and flushed face, fash is indistinct, extrudable white Fat bolt, is hard and dry usually, thirsty, and tongue is red, the thin Huang of tongue, superficial and rapid pulse.Carry out institute's interrogation later, be diagnosed as adolescent acne, through clothes Chinese medicine of the present invention is used, and is aided with after doctor trained in Western medicine externally applied drug external application, 2 courses for the treatment of of treatment, skin damaged all disappears, and subjective symptoms disappears, with Visit is not recurred for 1 month, has been fully recovered.
2nd, what ××, female, 18 years old.Patient facial region's life acne 4 months, it is red and swollen or have warts, it is yellow urine, indigestion and loss of appetite with constipation Abdominal distension, tongue is red, yellow and greasy fur, slippery and rapid pulse.Carry out institute's interrogation later, be diagnosed as adolescent acne, through taking Chinese medicine of the present invention, and be aided with After doctor trained in Western medicine externally applied drug external application, 3 courses for the treatment of of treatment, skin damaged all disappears, and subjective symptoms disappears, and follow-up is not recurred, fullyed recover from an illness for 1 month More.
Adolescent acne is mainly apt to occur in puberty men and women, is a kind of pilosebaceous follicle chronic inflammation, more because of eating and drinking without temperance, Overfeeding delicious food savoury, caused by lung stomach is damp and hot.The present invention suited the remedy to the case according to the cause of disease, in side nepal fleshspike herb, pectinate rungia herb can clearing lung-heat heat, dispel Irascibility, eliminating damp, detoxifying;Rheum officinale, China rose, fringed pink, japanese white birch bark can restore menstrual flow and invigorate blood circulation stagnation resolvation, and gut purge stomach are damp and hot, purte the white;Grass of meadow rue, Blumea, indian mockstrawberry root, golden cypress can clearing heat-fire, removing toxicity for detumescence;The public rattan of emblic leafflower root, horse hail, duck can clearing heat and promoting diuresis, removing toxic substances dissipates Knot;Herba portulacae, garden burnet, the Fructus Sophorae, Chinese violet can be clearing heat and detoxicating, cool blood detumescence;The fruit of summer cypress, korean pine seed, linseed can blood-nourishing dispel Wind, moistening dryness for relaxing bowels, skin of moistening;Ligusticum wallichii can promoting blood circulation, promote breath and open depression;The root of straight ladybell, radix polygonati officinalis can nourishing Yin and moistening lung, nourishing the stomach to improve the production of body fluid;It is sweet Grass can coordinating the drug actions of a prescription;In side all medicines share can play altogether clearing heat-fire, detoxicating and resolving a mass, healing up sore and subduing swelling, cooling blood and dissolving stasis, nourishing the blood to expel wind, The effect of moist skin, good absorbing effect is evident in efficacy, has no toxic side effect and clinical adverse, another modern pharmacological research table It is bright:Rheum officinale has broad-spectrum antiviral, antibacterial and antimycotic effect, the preventing and treating available for various inflammation;Fringed pink has diuresis, suppression The effect of bacterium;Golden cypress plays the role of antibacterial, convergence, antiulcer, anti-inflammatory, and to symptoms such as various skin wet poisons, sores, effect is good It is good;Garden burnet, the Fructus Sophorae can reduce the permeability of blood vessel, reduce inflammatory and ooze out;Chinese violet has the effect such as heat-clearing, detumescence, anti-inflammatory;Horse Tooth bamboo water pipe is applied to inflammation skin, can be effectively increased the oxidation resistance of Skin Cell, reduce inflammation symptom.Therefore full side is shared, And it is aided with doctor trained in Western medicine externally applied drug external application for curing, treat both principal and secondary aspect of disease, curative effect is substantially, uneasy to recur, and adolescent acne is controlled according to clinical verification More rate is higher.

Claims (3)

1. a kind of instant particles as Chinese medicine for being used to treat adolescent acne, it is characterised in that:The raw material of the effective ingredient is made Composition and parts by weight are:
30~60 parts of Herba portulacae, 20~30 parts of the root of straight ladybell, 15~30 parts of horse hail, 15~30 parts of emblic leafflower root,
15~30 parts of rattan of duck public affairs, 10~30 parts of korean pine seed, 10~30 parts of fringed pink, 10~30 parts of japanese white birch bark
10~30 parts of blumea, 10~25 parts of garden burnet, 10~25 parts of the fruit of summer cypress, 10~25 parts of the Fructus Sophorae,
9~15 parts of pectinate rungia herb, 9~15 parts of radix polygonati officinalis, 9~15 parts of nepal fleshspike herb, 6~15 parts of grass of meadow rue,
6~15 parts of Ligusticum wallichii, 6~12 parts of linseed, 6~12 parts of radix glycyrrhizae, 6~12 parts of China rose,
3~9 parts of Chinese violet, 3~9 parts of golden cypress, 3~6 parts of indian mockstrawberry root, 1~5 part of rheum officinale.
2. a kind of instant particles as Chinese medicine for being used to treat adolescent acne according to claim 1, it is characterised in that:It is made described The raw material of effective ingredient is constituted and parts by weight are:
40 parts of Herba portulacae, 25 parts of the root of straight ladybell, 25 parts of horse hail, 20 parts of emblic leafflower root,
20 parts of rattan of duck public affairs, 20 parts of korean pine seed, 15 parts of fringed pink, 15 parts of japanese white birch bark
15 parts of blumea, 15 parts of garden burnet, 12 parts of the fruit of summer cypress, 12 parts of the Fructus Sophorae,
12 parts of pectinate rungia herb, 12 parts of radix polygonati officinalis, 12 parts of nepal fleshspike herb, 12 parts of grass of meadow rue,
10 parts of Ligusticum wallichii, 10 parts of linseed, 9 parts of radix glycyrrhizae, 9 parts of China rose,
6 parts of Chinese violet, 6 parts of golden cypress, 4 parts of indian mockstrawberry root, 2 parts of rheum officinale.
3. a kind of preparation method for being used to treat the instant particles as Chinese medicine of adolescent acne, it is characterised in that comprise the following steps that:
(1)By Herba portulacae, the root of straight ladybell, horse hail, emblic leafflower root, the public rattan of duck, korean pine seed, fringed pink, japanese white birch bark, blumea, garden burnet, summer cypress Son, the Fructus Sophorae, pectinate rungia herb, radix polygonati officinalis, nepal fleshspike herb, grass of meadow rue, linseed, China rose, Chinese violet, indian mockstrawberry root, rheum officinale, which are cleaned, to be dried After be well mixed, be put into container, in a reservoir add 6~8 times amount water, heating boil 2~3 hours, immersion liquid is taken after cooling; The water of 4~6 times of amounts is added in the remaining dregs of a decoction, heating is boiled 1~2 hour, and immersion liquid is taken after cooling;Merge gained twice to soak Liquid, heating is concentrated by evaporation as the thick paste of relative density 1.15~1.25, standby;
(2)Take the sprinkling of Ligusticum wallichii piece yellow rice wine uniform, slightly vexed, it is degree to micro- Jiao to put stir-fry in pot, and taking-up is cooled, and crushing is ground, and crosses 100 Mesh dusting cover, obtains fine powder, standby;
(3)Net licorice tablet is taken, cooked honey and a little boiling water is added, it is slightly vexed after mixing thoroughly, put in frying container, slow fire is fried to depth Yellow, is taken out when tack-free, cools, and crushing is ground, and is crossed 100 mesh dusting covers, is obtained fine powder, standby;
(4)Golden cypress piece is taken, is sprayed with salt solution, is mixed thoroughly, the micro- stir-fry of the interior slow fire of pot is put, taking-up is cooled, dried, and crushing is ground, and crosses 100 Mesh dusting cover, obtains fine powder, standby;
(5)By step(1)The thick paste of gained, with step(2), step(3), step(4)The fine powder mixing of middle gained, plus auxiliary material sugarcane Sugar and dextrin, which are well mixed, is made particle, after dry, whole grain, is packaged into every bag of 8g instant particles as Chinese medicine.
CN201710490015.4A 2017-06-25 2017-06-25 A kind of instant particles as Chinese medicine and preparation method for being used to treat adolescent acne Pending CN107095961A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648444A (en) * 2017-11-24 2018-02-02 青岛大学附属医院 A kind of slow release cutaneous penetration for vulva seborrhea pastes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106038995A (en) * 2016-07-15 2016-10-26 夏雪飞 Traditional Chinese medicine granules for treating perioral dermatitis and preparation method
CN106692786A (en) * 2017-02-16 2017-05-24 颜维凌 Traditional Chinese medicine formula of acne treatment capsule

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106038995A (en) * 2016-07-15 2016-10-26 夏雪飞 Traditional Chinese medicine granules for treating perioral dermatitis and preparation method
CN106692786A (en) * 2017-02-16 2017-05-24 颜维凌 Traditional Chinese medicine formula of acne treatment capsule

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648444A (en) * 2017-11-24 2018-02-02 青岛大学附属医院 A kind of slow release cutaneous penetration for vulva seborrhea pastes

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Application publication date: 20170829