CN107157846A - A kind of anti-acne facial treatment mask - Google Patents
A kind of anti-acne facial treatment mask Download PDFInfo
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- CN107157846A CN107157846A CN201710461932.XA CN201710461932A CN107157846A CN 107157846 A CN107157846 A CN 107157846A CN 201710461932 A CN201710461932 A CN 201710461932A CN 107157846 A CN107157846 A CN 107157846A
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- acne
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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Abstract
The present invention provides the compositions such as a kind of anti-acne facial treatment mask, including affine cudweed extract, Aralia woods root bark extract, Herba Oxalidis Corniculatae extract, NMF, anti-sensitizer.There is facial mask and suppress inflammatory factor secretion, remove microorganism secretion thing, reduce clogging of pores, promote microcirculation to be reconstructed, be finally reached significant acne-removing;Promote the skin reconstruction regeneration at pockmark, and then be effectively promoted the elimination of acne scar;Can the generation of scavenging capacity oxygen radical, improve the oxidation resistance of cell viability and cell itself, and then enhance the anti-aging ability of skin, can make that skin and muscles are fair, it is more flexible;Facial mask composition safety, does not stimulate gently, has no toxic side effect, and prepares simple, wide market.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of anti-acne facial treatment mask.
Background technology
When the acne origin cause of formation is usually puberty, internal hormone can stimulate hair growth, and smegma is vigorous, causes
The core of clogging of pores one acne of formation.One micro mist thorn skin surface from formed to growing needs the growth of 6 to 9 months
Phase.Micro mist thorn blocks pore and induces inflammation, is that papule, useless fellow, tubercle and tumour originate root.Traditional treatment is removing table
The acne in face, and micro mist thorn stops longer for a period of time!Then the situation of acne recurrent exerbation is formd, causes sebaceous glands long
The reason for phase sebum secreted vigorous long-term long acne is endocrinopathy, and the product of professional removing acne is mainly regulation endocrine
Lack of proper care, the method such as sterilization.Skin Cell Physiologic Studies points out that sensitiveness skin is because Skin Cell is damaged, and makes skin
Immunity degradation, failing to repair these damaged cells in time, will cause they constantly divide immunity it is bad with
And sebum film secretes incomplete Skin Cell, therefore the puzzlement of various sensitiveness skin and many sequelae are produced, because mistake
Quick and produce pigementation caused by skin damage, redness, pore is thick, acne small pox, color spot, aging wrinkle.
Chinese patent application CN 104434620A disclose a kind of acne-removing composition and preparation method thereof, including Ka Boshu
Fat, hydroxyethyl cellulose, glycine betaine, menthol, salicylic acid, propane diols, the de- composition such as acyl chitin, the composition of the invention contain
Some salicylic acids can dissolve the composition material between cutin, cuticula is come off, and be used for a long time, and burden can be caused to skin, quick
Feel skin, fat leakage property skin is not suitable for using salicylated product.
At present, many product for resolving poxes add the compositions such as hormones, antibiotic, tartaric acid on the market, and excitant and side effect are big, meeting
Damage cuticula or produce drug resistance, destroy the microecological balance of skin, cause more serious other skin problems, such as hair purulence.
Or the products of anti-acne effect are much declared, effect is single, and anti-acne is not obvious.So, prior art lacks safety, anti-acne effect
Substantially, the high product for resolving poxes of cost performance.
The content of the invention
In view of the shortcomings of the prior art, the present invention provides a kind of anti-acne facial treatment mask, affine cudweed extract, Aralia wood root skins are carried
Thing and Herba Oxalidis Corniculatae extract are taken as active component, can effectively suppress inflammation, microorganism secretion thing is removed, clogging of pores is reduced,
Oxidative damage is reduced, promotes microcirculation, so as to reach the effect of anti-acne skin care.
To reach above-mentioned purpose, the present invention provides following technical scheme:
A kind of anti-acne facial treatment mask includes following parts by weight of component:0.4-1.1 parts of plant composition;Wherein, the plant
Composition be affine cudweed extract, Aralia woods root bark extract, Herba Oxalidis Corniculatae extract, and affine cudweed extract, Aralia woods root skin extract
Thing, the weight ratio of Herba Oxalidis Corniculatae extract are (2-5):(1-3):(1-3).
The preparation method of the plant composition comprises the following steps:Affine cudweed, Aralia woods root skin, creeping oxalis are cleaned dry
It is dry, pulverizer is added together and is crushed, and 60-80 mesh sieves is crossed, by solid-liquid ratio 1:(10-30) adds 70-90% ethanol, in 50-70 DEG C
Lower ultrasonic extraction 10-30min, ultrasonic power 130-150W, extract solution centrifuges 10-30min, supernatant under 4000-6000r/min
Liquid is concentrated to obtain plant composition.
The facial mask also includes following parts by weight of component:10-25 parts of NMF, 0.5-2 parts of thickener, anti-sensitizer 0.2-1
Part, 0.02-0.1 parts of preservative, 0.1-0.3 parts of triethanolamine, 0.2-0.5 parts of EDETATE SODIUM, PEG-60 rilanit specials 0.2-
0.8 part, deionization is to 100 parts.
The NMF is glycerine, butanediol, propane diols, the mixture of Sodium Hyaluronate;The thickener be xanthans,
The mixture of carbomer, reed fragrant plant glue.
The anti-sensitizer is dipotassium glycyrrhizinate, the mixture of allantoin;The preservative is methyl hydroxybenzoate, Nipasol
Mixture.
The present invention also provides a kind of preparation method of anti-acne facial treatment mask, comprises the following steps:By NMF, thickener,
Anti-sensitizer, EDETATE SODIUM, PEG-60 rilanit specials, deionized water are mixed in addition agitated kettle, are heated with stirring to 70-85
DEG C, stirring and dissolving is complete;40-50 DEG C is cooled to, triethanolamine, above-mentioned plant composition, preservative is added, stirs, it is cold
But discharge.
The affine cudweed extract rich in flavonoid glycoside, volatile oil, alkaloid, sterol, vitamin, phytochrome and calcium, copper,
The trace elements such as potassium, wherein flavonoid content are more.Make with anti-oxidant, antiallergy, anti-inflammatory, antibacterial, cytoprotection
With, regulation blood circulation and the antiviral extensive physiologically active of grade, and toxicity is relatively low, may be used as the natural additive of cosmetics.
Affine cudweed flavones can be formed with Scavenger of ROS prevention free radical, can also be prevented for established free radical with it is intracellular normal
Composition combine cause damage, while increase antioxidase activity further adjust intracellular oxidation balance.Affine cudweed is yellow
Ketone can suppress the growth of cell surface bacterium, while the generation of its secretion can be reduced, and then reduce the contamination and plugging to pore;Separately
On the one hand, affine cudweed flavones can suppress the secretion of various inflammatory cytokines and expression is synthesized, while vascular permeability can be regulated
Property, to reach reduction degree of inflammation, accelerate the effect of inflammatory resolution.
Suo Shu Aralia wood root bark extract primary efficacies material is saponin(e, and it has regulation blood vessel, the effects such as anti-inflammatory is anti-oxidant.
It can provide effective antioxidant effect and increase cell viability, can also improve the activity of relative antioxidant enzyme, it is established that thin
The oxidation balance of intracellular, reduces the cellular damage that free radical is caused with lipid peroxidation.Aralia wood root skin saponin(e can be played substantially
Suppress inflammatory effect, can suppress to induce the substance activating inflammation systems of inflammation, the expression of inflammation relevant enzyme be prevented, while can also
Immunologic balance is adjusted, and then makes the inflammation rapid regression at small pox position, and accelerates residue cleaning, accelerates wound healing, quickly
Go pockmark.
Creeping oxalis flavones is its main composition in the Herba Oxalidis Corniculatae extract.It is directed to skin surface, can effectively and
What is had no toxic side effect suppresses the bacterial reproduction on skin;The permeability of capillary of skin is adjusted, suppresses the release of anti-inflammatory agent.
In addition, creeping oxalis flavones can improve antioxidase activity well, while its own can also give play to the effect for removing free radical.
Compared with prior art, the device have the advantages that as follows:(1) facial mask of the invention with the addition of natural mouse song
Careless extract, Aralia woods root bark extract and Herba Oxalidis Corniculatae extract active component, have facial mask and suppress inflammatory factor secretion, remove
Microorganism secretion thing, the effects such as reducing clogging of pores, prevention oxidative damage.Externally, creeping oxalis flavones can suppress skin surface
Microbial reproduction, affine cudweed flavones further suppresses surface microorganism growth, prevents metabolism is vigorous from causing inflammation;Internally,
Affine cudweed flavones can suppress the secretion and expression of inflammatory factor, and from the generation of interior prevention inflammation, knot closes Aralia wood saponin(e and effectively suppressed
The activation of inflammation, prevents inflammation relevant enzyme from producing, creeping oxalis flavones adjustment capillary of skin, promotes microcirculation to be reconstructed, enters
One step makes anti-inflammatory agent disappear, and reduces inflammatory effect, and several compositions complement each other, and are finally reached significant acne-removing;(2) originally
The facial mask of invention can promote the skin reconstruction at pockmark to regenerate, and then be effectively promoted the elimination of acne scar;(3) face of the invention
Film energy scavenging capacity oxygen radical is generated, and improves the oxidation resistance of cell viability and cell itself, and then enhances skin
Anti-aging ability;(4) facial mask composition of the invention safety, does not stimulate gently, has no toxic side effect, and prepares simple, market prospects
It is wide.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.The anti-acne facial treatment mask of the present invention of embodiment 1~5 is matched somebody with somebody
Fang Jianbiao mono-
Table one
The preparation method of anti-acne facial treatment mask, comprises the following steps described in embodiment 1~5:
NMF, thickener, anti-sensitizer, EDETATE SODIUM, PEG-60 rilanit specials, deionized water are mixed addition
In agitated kettle, 85 DEG C are heated with stirring to, stirring and dissolving is complete;50 DEG C are cooled to, triethanolamine, plant composition, anti-corrosion is added
Agent, stirs, cooling discharging.
Comparative example 1
Difference with embodiment 1 is not add affine cudweed extract, and other preparation conditions and method are same as Example 1.
Comparative example 2
Difference with embodiment 1 is non-Jia Ru Aralia wood root bark extracts, other preparation conditions and method and the phase of embodiment 1
Together.
Comparative example 3
Difference with embodiment 1 is not add Herba Oxalidis Corniculatae extract, and other preparation conditions and method are same as Example 1.
Comparative example 4
Difference with embodiment 1 is not add affine cudweed extract, Aralia woods root bark extract, Herba Oxalidis Corniculatae extract, other
Preparation condition and method are same as Example 1.
Efficacy validation
To verify the anti-acne effect of anti-acne facial treatment mask of the present invention, now carry out following test.
Light, the ordinary whelk of moderate face is chosen (with reference to PillSburv and international improvement acne pulvis method diagnosis mild or moderate
Acne person) volunteer totally 100, wherein man 48, the people of female 52;Age between 17~35 years old, average age 28.3 years old;The course of disease
It is 4 weeks~7 years, average 3.5 years, 2 weeks before the skin care item are smeared, glucocorticosteroid hormone, tretinoin and antibioticses are not used
Medicine, no high fat of blood and hepatic and renal function are abnormal, excessive drinking of compacting, it is to avoid sunburst or ultraviolet excessive radiation.
Above-mentioned 100 volunteers are randomly divided into 10 groups, every group of 10 people, respectively experimental group 1~5, commercially available group and control
Group 1~4.Experimental group 1~5 respectively use the embodiment of the present invention 1~5 anti-acne facial treatment mask, control group 1~4 respectively using pair
The anti-acne facial treatment mask with good effects is claimed in the anti-acne facial treatment mask of ratio 1~4, commercially available group of use on the market.Subject
Wiped with warm water cleaning pars affecta skin disease after opening, it is daily sooner or later using counter sample 1 time, other drugs or skin care are disabled during use
Product, by a definite date 4 weeks.Before the treatment and after treatment, to the facial inflammatory damage sum of subject, (inflamed papules and useless fellow are total respectively
With), non-inflammatory lesions summation (summation of Whiteheads and blackhead) count, while bad anti-after record use in detail
Should.
Evaluation criterion:
Base is cured:Therapeutic index >=90%;
It is effective:60%≤therapeutic index < 90%;
It is progressive:20%≤therapeutic index < 60%;
It is invalid:Therapeutic index < 20%.
Total skin damaged number × 100% before therapeutic index=(total skin damaged number after total skin damaged number-treatment before treatment)/treatment;
Effective percentage=(base is cured number+effective number)/total number of persons × 100%.
Experimental result is shown in Table two:
Table two
Group | It is basic to cure | It is effective | It is progressive | It is invalid | It is efficient |
Experimental group 1 | 6 | 3 | 1 | 0 | 100 |
Experimental group 2 | 5 | 5 | 0 | 0 | 100 |
Experimental group 3 | 7 | 2 | 1 | 0 | 100 |
Experimental group 4 | 6 | 2 | 1 | 1 | 90 |
Experimental group 5 | 7 | 1 | 1 | 1 | 90 |
Control group 1 | 0 | 3 | 3 | 4 | 30 |
Control group 2 | 3 | 2 | 2 | 3 | 50 |
Control group 3 | 1 | 3 | 3 | 3 | 40 |
Control group 4 | 3 | 2 | 2 | 3 | 50 |
Commercially available group | 4 | 1 | 1 | 4 | 60 |
Experimental result illustrates that anti-acne facial treatment mask of the present invention has good acne-removing, by embodiment 1~5 and comparative example
1st, 2,3 contrasts understand plant component Synergistic of the present invention, are contrasted by embodiment 1~5 and comparative example 4 and understand that the present invention mainly has
Effect composition is plant component.
Skin-care effect is verified
Atraumatic human body evaluation is carried out to the anti-acne facial treatment mask prepared by embodiment 1~5, while with a commercially available
Lay claim to the anti-acne facial treatment mask of good skin-care effect as a control group.
Test object:Each experimental group is 20 women (35-50 Sui);Test zone:Facial zone;Use:Daily two
It is secondary, persistently using 4 weeks;Test event:The soft degree of skin, skin elasticity.Result on trial refers to table three.
Table three
Description of test anti-acne facial treatment mask of the present invention has good nourishing maintenance effect, is far more than commercially available product and contrast
Example, illustrates this scientific formulation, the plant composition Synergistic used.
Above example only illustrates embodiment of the present invention, does not have any formal limitation to the present invention;Appoint
What is engaged in professional and technical personnel, all has the ability to make some changes using the technology contents disclosed or modifies, as equivalent
The equivalent embodiment of change, according to the technology of the present invention essence, simply modification, equivalent variations and modification is carried out to the present invention, is belonged to
In the range of technical solution of the present invention.
Claims (7)
1. a kind of anti-acne facial treatment mask, it is characterised in that the facial mask includes following parts by weight of component:Plant composition 0.4-
1.1 part;
Wherein, the plant composition is affine cudweed extract, Aralia woods root bark extract, Herba Oxalidis Corniculatae extract.
2. a kind of anti-acne facial treatment mask according to claim 1, it is characterised in that the affine cudweed extract, Aralia wood roots
Bark extract, the weight ratio of Herba Oxalidis Corniculatae extract are (2-5):(1-3):(1-3).
3. a kind of anti-acne facial treatment mask according to claim 1, it is characterised in that the preparation method of the plant composition
Comprise the following steps:By affine cudweed, Aralia woods root skin, creeping oxalis clean dry, pulverizer is added together and is crushed, 60-80 mesh sieves are crossed,
By solid-liquid ratio 1:(10-30) adds 70-90% ethanol, in ultrasonic extraction 10-30min at 50-70 DEG C, ultrasonic power 130-
150W, extract solution centrifuges 10-30min under 4000-6000r/min, and supernatant is concentrated to obtain plant composition.
4. a kind of anti-acne facial treatment mask according to claim 1, it is characterised in that the facial mask also includes following parts by weight
Component:
Deionization is to 100 parts.
5. a kind of anti-acne facial treatment mask according to claim 4, it is characterised in that the NMF be glycerine, butanediol,
The mixture of propane diols, Sodium Hyaluronate;The thickener is xanthans, carbomer, the mixture of reed fragrant plant glue.
6. a kind of anti-acne facial treatment mask according to claim 4, it is characterised in that the anti-sensitizer be dipotassium glycyrrhizinate,
The mixture of allantoin;The preservative is methyl hydroxybenzoate, the mixture of Nipasol.
7. a kind of preparation method of the anti-acne facial treatment mask as described in claim any one of 1-6, it is characterised in that including following step
Suddenly:
NMF, thickener, anti-sensitizer, EDETATE SODIUM, PEG-60 rilanit specials, deionized water are mixed and add stirring
In pot, 70-85 DEG C is heated with stirring to, stirring and dissolving is complete;40-50 DEG C is cooled to, triethanolamine is added, such as claim 1 institute
Plant composition, preservative are stated, is stirred, cooling discharging.
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CN201710461932.XA CN107157846A (en) | 2017-06-16 | 2017-06-16 | A kind of anti-acne facial treatment mask |
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CN201710461932.XA CN107157846A (en) | 2017-06-16 | 2017-06-16 | A kind of anti-acne facial treatment mask |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113318038A (en) * | 2021-07-17 | 2021-08-31 | 宁夏医科大学 | Acne-removing and anti-inflammatory sophora alopecuroide total alkaloid mask and preparation method thereof |
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2017
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113318038A (en) * | 2021-07-17 | 2021-08-31 | 宁夏医科大学 | Acne-removing and anti-inflammatory sophora alopecuroide total alkaloid mask and preparation method thereof |
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