CN107308042A - One kind cleaning anti-acne trace facial mask - Google Patents
One kind cleaning anti-acne trace facial mask Download PDFInfo
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- CN107308042A CN107308042A CN201710461559.8A CN201710461559A CN107308042A CN 107308042 A CN107308042 A CN 107308042A CN 201710461559 A CN201710461559 A CN 201710461559A CN 107308042 A CN107308042 A CN 107308042A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The compositions such as anti-acne trace facial mask, including wedelia chinensis extract, false acid pulp extract, dye yam extract, glycerine, butanediol, propane diols, glycine betaine are cleaned the invention provides one kind.The facial mask of the present invention can mitigate cell because damage and caused by inflammatory reaction, suppress the generation of inflammatory mediator, and then reduce the skin damage produced by inflammation, and can effective cleaning skin, the reparation of the regression and pockmark of promotion acne；In addition, facial mask can improve blood circulation, promote the synthesis of collagen, reach reparation and the palingenesis of skin；Can also deep water supplement, formation water lock wall, the Stability Analysis of Structures of maintenance skin, so that skin high resilience.
Description
Technical field
The present invention relates to cosmetic field, and in particular to one kind cleaning anti-acne trace facial mask.
Background technology
Acne is a kind of symptom destroyed to keratoderma, allow skin resistance to be deteriorated, and is also exactly always useless
Cutin will not tail off or come off automatically, but the arch-criminal as blocked pore, so as to form acne.The personage much liked to be beautiful is
Break away from acne ahead of time to tangle, treated using various methods, but it is obtained instead toward past event, so as to produce the acne for being very difficult to remove
Scar.
Now except the method for scar has：1st, dot matrix laser：It can effectively remove scar, remove caused by pigmentation
Trace, the improvement of pockmark can also good pore refining, bactericidal antiphlogistic.2nd, LED blue lights：It is to subcutaneous glue by laser
Former egg stimulating growth, is repaired for acne print pockmark, and the improvement colour of skin is dark yellow, well lifting skin gloss, while laser is also
Can be thick to pore, the colour of skin is uneven, and wound scars etc. are treated, but to formulate rational according to personal different situations
Scheme, repeatedly be treated.These light treatment methods be largely by stimulating skin regeneration, there is certain risk,
Or have side effect, so, present people more favor the gentle Traditional-Chinese-medicine-type facial mask for having anti-acne trace to act on.
The content of the invention
Based on this, anti-acne trace facial mask is cleaned it is an object of the invention to provide one kind.Wedelia chinensis extract, false acid pulp are carried
Take thing and dye yam extract as active component, assign facial mask and have cleaning and effect of anti-acne trace concurrently.
In order to achieve the above object, the present invention provides following technical scheme：
One kind cleaning anti-acne trace facial mask includes 1-5 parts of wedelia chinensis extract, 1-3 parts of false acid pulp extract, dye yam extract
1-5 parts.
The facial mask also includes 5-10 parts of glycerine, 5-15 parts of butanediol, 1-10 parts of propane diols, 2-4 parts of glycine betaine, carbomer
0.05-0.15 parts, 0.05-0.15 parts of xanthans, 0.01-0.1 parts of Sodium Hyaluronate, 0.1-0.3 parts of triethanolamine, PEG-6 it is pungent
Acid/1-5 parts of glycerol decanoate class, 1-3 parts of Cremophor RH40,0.04-0.06 parts of allantoin, Phenoxyethanol 0.2-0.8
Part, 1-4 parts of wedelia chinensis extract, 1-3 parts of false acid pulp extract, 1-4 parts of dye yam extract.
Preferably, the facial mask includes 8 parts of glycerine, 10 parts of butanediol, 5 parts of propane diols, 3 parts of glycine betaine, carbomer 0.1
Part, 0.1 part of xanthans, 0.05 part of Sodium Hyaluronate, 0.2 part of triethanolamine, 3 parts of PEG-6 caprylic/caprics glyceride type, PEG-
40 2 parts of rilanit specials, 0.05 part of allantoin, 0.5 part of Phenoxyethanol, 3 parts of wedelia chinensis extract, 2 parts of false acid pulp extract, potato
3 parts of Liang extracts.
The present invention also provides a kind of preparation method for cleaning anti-acne trace facial mask, comprises the following steps：(1) by glycerine, fourth two
Alcohol, propane diols, glycine betaine, carbomer, xanthans, Sodium Hyaluronate, PEG-6 caprylic/caprics glyceride type, PEG-40 hydrogenation castors
Sesame oil, allantoin, deionized water mixing are added in agitated kettle, are heated with stirring to 80-85 DEG C, are stirred；
(2) 40-45 DEG C is cooled to, triethanolamine, wedelia chinensis extract, false acid pulp extract, dye yam extract, benzene is added
Oxyethanol, stirs, cooling discharging.
The drying herb of described wedelia chinensis system composite family amphibious crab Dendranthema, first recorded in《The sward property of medicine is standby will》.Modernization
Learn composition Study to show, main composition is wedelolactone in wedelia chinensis extract.It can protect cell not by cell
Toxicant is damaged, and can suppress inflammatory mediator generation by suppressing lipoxygenase activity, and then reduce the breaking-out of inflammation.For
Pockmark, wedelolactone can also reduce wound area, increase wound tensity, accelerate the speed that wound is repaired.
The high easily storage of described false acid pulp fruit yield, patent medicine is cheap, and it is nontoxic that false acid pulp seed makees effect physical security,
Opsonic action is strong, with higher application prospect.False acid pulp extract main pharmacodynamics composition is flavone compound, wherein mainly
Exist in flavone glycoside form.Flavone glycoside possesses the antioxidation activity more stronger than vitamin C, can be with carrying out in oxidation reaction
Free radical stable bond, generates stable compound, prevents further to aoxidize with intracellular other compositions, cell is kept stable.
In addition, the phenomenon of Synergistic can also occur with other antioxidant contents for flavone glycoside, further cell is delayed further to send out
The speed of raw oxidation.
Described dye yam also known as hematogen, Jin Huaguo, are conventional Chinese herbal medicines simply.The primary efficacy material of dye yam extract is
Dye yam tannin.Dye yam tannin has strong reducing property, can provide sufficient Hydrogen Proton and be combined into stable intermediate with free radical, suppress certainly
By the chain reaction of base, and then the free radical in scavenger-cell；Remove due to the free radical that radiation is produced, cell is protected
Shield, mitigates the inflammatory reaction therefore produced；It can be coupled with metal ion, reduce the oxidation reaction of metal ion catalysis；It is right
The microprotein of skin surface is solidified, and inhibitory effect is produced in skin surface, reduces what is produced due to microbial reproduction
Secretion is impacted to skin.
Compared with prior art, the device have the advantages that as follows：(1) facial mask of the invention contains natural component Peng
Qi chrysanthemums lactone, false acid pulp flavones and dye yam tannin, wherein dye yam tannin can mitigate cell because of damage and caused by inflammatory reaction, Peng
Qi chrysanthemums lactone further suppresses the generation of inflammatory mediator, and then reduces the skin damage produced by inflammation, three kinds of equal energy of composition
Antioxidation is produced, is prevented because inflammation is excessively accumulated with intracellular free radicals caused by variola, three kinds of composition collaborations are made
With, can effective cleaning skin, promote the reparation of the regression and pockmark of acne；(2) facial mask of the invention can improve blood circulation, promote
Enter the synthesis of collagen, reach reparation and the palingenesis of skin；(3) facial mask of the invention is also containing strong sweet of moisturizing water lock
Oil, butanediol, propane diols, beet alkali composition, can deep water supplement, formation water lock wall, the Stability Analysis of Structures of maintenance skin, so that skin
Skin high resilience；(4) facial mask composition of the invention safety, is not stimulated gently, and preparation technology is simple, wide market.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
The following component title occurred in text is INCI (International Nomenclature Cosmetic
Ingredient, i.e. international cosmetic raw material name institute to defined title, including:PEG-6 caprylic/capric glyceride
Class.
The present invention cleaning anti-acne trace face pack prescription of embodiment 1~5 is shown in Table one
Table one
Present invention cleaning anti-acne trace facial mask preparation method comprises the following steps in embodiment 1~5：
(3) by glycerine, butanediol, propane diols, glycine betaine, carbomer, xanthans, Sodium Hyaluronate, the PEG-6 octanoic acids/last of the ten Heavenly stems
Acid glycerol esters, Cremophor RH40, allantoin, deionized water mixing are added in agitated kettle, are heated with stirring to 85 DEG C, are stirred
Mix uniform；
(4) 45 DEG C are cooled to, triethanolamine, wedelia chinensis extract, false acid pulp extract, dye yam extract, benzene oxygen is added
Ethanol, stirs, cooling discharging.
Comparative example 1
Difference with embodiment 1 is not add wedelia chinensis extract, and other preparation conditions and method are same as Example 1.
Comparative example 2
Difference with embodiment 1 is not add false acid pulp extract, and other preparation conditions and method are same as Example 1.
Comparative example 3
Difference with embodiment 1 is not add dye yam extract, and other preparation conditions and method are same as Example 1.
Comparative example 4
Difference with embodiment 1 is not add wedelia chinensis extract, false acid pulp extract, dye yam extract, other preparations
Condition and method are same as Example 1.
The patient that clinical case 100 includes different degrees of acne scar is divided into ten groups, daily using embodiment 1~5, control
Group 1~4, commercially available group (claiming the like product with good anti-acne scar effect on the market) once, adheres to two months, obtains effect
As shown in Table 2：
Table two
| It is efficient | Cure rate | |
| Embodiment 1 | 90% | 80% |
| Embodiment 2 | 90% | 80% |
| Embodiment 3 | 80% | 80% |
| Embodiment 4 | 90% | 70% |
| Embodiment 5 | 80% | 70% |
| Control group 1 | 50% | 40% |
| Control group 2 | 50% | 30% |
| Control group 3 | 40% | 30% |
| Control group 4 | 30% | 20% |
| Commercially available group | 60% | 50% |
Efficacy validation
For the anti-acne effect of checking present invention cleaning anti-acne trace facial mask, now carry out following test.
Light, the ordinary whelk of moderate face is chosen (with reference to PillSburv and international improvement acne pulvis method diagnosis mild or moderate
Acne person) volunteer totally 100, wherein man 48, the people of female 52；Age between 17~35 years old, average age 28.3 years old；The course of disease
It is 4 weeks~7 years, average 3.5 years, 2 weeks before the skin care item are smeared, glucocorticosteroid hormone, tretinoin and antibioticses are not used
Medicine, no high fat of blood and hepatic and renal function are abnormal, excessive drinking of compacting, it is to avoid sunburst or ultraviolet excessive radiation.
Above-mentioned 100 volunteers are randomly divided into 10 groups, every group of 10 people, respectively experimental group 1~5, commercially available group and control
Group 1~4.Experimental group 1~5 uses the cleaning anti-acne trace facial mask of the embodiment of the present invention 1~5 respectively, and control group 1~4 is used respectively
The cleaning anti-acne trace facial mask with good effects is claimed in the cleaning anti-acne trace facial mask of comparative example 1~4, commercially available group of use on the market.
It is daily to use counter sample 1 time after subject is opened with warm water cleaning pars affecta skin disease wiping, other drugs or shield are disabled during use
Skin product, by a definite date 4 weeks.Before the treatment and after treatment, to the facial inflammatory damage sum of subject, (inflamed papules and useless fellow are total respectively
With), non-inflammatory lesions summation (summation of Whiteheads and blackhead) count, while bad anti-after record use in detail
Should.Evaluation criterion：
Base is cured：Therapeutic index >=90%；
It is effective：60%≤therapeutic index ＜ 90%；
It is progressive：20%≤therapeutic index ＜ 60%；
It is invalid：Therapeutic index ＜ 20%.
Total skin damaged number × 100% before therapeutic index=(total skin damaged number after total skin damaged number-treatment before treatment)/treatment；
Effective percentage=(base is cured number+effective number)/total number of persons × 100%.
Experimental result is shown in Table three：
Table three
| Group | It is basic to cure | It is effective | It is progressive | It is invalid | It is efficient |
| Experimental group 1 | 6 | 3 | 1 | 0 | 100 |
| Experimental group 2 | 5 | 5 | 0 | 0 | 100 |
| Experimental group 3 | 7 | 2 | 1 | 0 | 100 |
| Experimental group 4 | 6 | 2 | 1 | 1 | 90 |
| Experimental group 5 | 7 | 1 | 1 | 1 | 90 |
| Control group 1 | 0 | 3 | 3 | 4 | 30 |
| Control group 2 | 3 | 2 | 2 | 3 | 50 |
| Control group 3 | 1 | 3 | 3 | 3 | 40 |
| Control group 4 | 3 | 2 | 2 | 3 | 50 |
| Commercially available group | 4 | 1 | 1 | 4 | 60 |
Experimental result illustrates that present invention cleaning anti-acne trace facial mask has good acne-removing, by embodiment 1~5 and contrast
The contrast of example 1,2,3 understands plant component Synergistic of the present invention, is contrasted by embodiment 1~5 and comparative example 4 and understands that the present invention is main
Active ingredient is plant component.
The above described is only a preferred embodiment of the present invention, being not the limitation for making other forms to the present invention, appoint
What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc.
Imitate embodiment and be applied to other fields, but every without departing from technical solution of the present invention content, the technical spirit according to the present invention
Any simple modification, equivalent variations and the remodeling made to above example, still fall within the protection domain of technical solution of the present invention.
Claims (6)
1. one kind cleaning anti-acne trace facial mask, it is characterised in that the facial mask includes wedelia chinensis extract, false acid pulp extract, potato
Liang extracts.
2. a kind of cleaning anti-acne trace facial mask according to claim 1, it is characterised in that the facial mask is extracted including wedelia chinensis
1-5 parts of thing, 1-3 parts of false acid pulp extract, 1-5 parts of dye yam extract.
3. a kind of cleaning anti-acne trace facial mask according to claim 1, it is characterised in that the facial mask includes glycerine, fourth two
Alcohol, propane diols, glycine betaine, carbomer, xanthans, Sodium Hyaluronate, triethanolamine, PEG-6 caprylic/caprics glyceride type,
Cremophor RH40, allantoin, Phenoxyethanol, wedelia chinensis extract, false acid pulp extract, dye yam extract.
4. a kind of cleaning anti-acne trace facial mask according to claim 3, it is characterised in that the facial mask includes glycerine 5-10
Part, 5-15 parts of butanediol, 1-10 parts of propane diols, 2-4 parts of glycine betaine, 0.05-0.15 parts of carbomer, 0.05-0.15 parts of xanthans,
0.01-0.1 parts of Sodium Hyaluronate, 0.1-0.3 parts of triethanolamine, 1-5 parts of PEG-6 caprylic/capric glyceride types, PEG-40 hydrogenations
1-3 parts of castor oil, 0.04-0.06 parts of allantoin, 0.2-0.8 parts of Phenoxyethanol, 1-4 parts of wedelia chinensis extract, false acid pulp are extracted
1-3 parts of thing, 1-4 parts of dye yam extract.
5. a kind of cleaning anti-acne trace facial mask according to claim 1, it is characterised in that the facial mask includes 8 parts of glycerine, fourth
10 parts of glycol, 5 parts of propane diols, 3 parts of glycine betaine, 0.1 part of carbomer, 0.1 part of xanthans, 0.05 part of Sodium Hyaluronate, three ethanol
0.2 part of amine, 3 parts of PEG-6 caprylic/caprics glyceride type, 2 parts of Cremophor RH40,0.05 part of allantoin, Phenoxyethanol
0.5 part, 3 parts of wedelia chinensis extract, 2 parts of false acid pulp extract, 3 parts of dye yam extract.
6. a kind of preparation method that anti-acne trace facial mask is cleaned as described in claim any one of 1-5, it is characterised in that including following
Step：
(1) it is glycerine, butanediol, propane diols, glycine betaine, carbomer, xanthans, Sodium Hyaluronate, PEG-6 caprylic/caprics is sweet
Grease class, Cremophor RH40, allantoin, deionized water mixing are added in agitated kettle, are heated with stirring to 80-85 DEG C, are stirred
Mix uniform；
(2) 40-45 DEG C is cooled to, triethanolamine, wedelia chinensis extract, false acid pulp extract, dye yam extract, benzene oxygen second is added
Alcohol, stirs, cooling discharging.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710461559.8A CN107308042A (en) | 2017-06-16 | 2017-06-16 | One kind cleaning anti-acne trace facial mask |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710461559.8A CN107308042A (en) | 2017-06-16 | 2017-06-16 | One kind cleaning anti-acne trace facial mask |
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| Publication Number | Publication Date |
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| CN107308042A true CN107308042A (en) | 2017-11-03 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753403A (en) * | 2017-11-28 | 2018-03-06 | 湖南康麓生物科技有限公司 | A kind of natural nutrition moisture saver mask and preparation method thereof |
| CN112690452A (en) * | 2021-01-13 | 2021-04-23 | 中国热带农业科学院海口实验站 | Preparation method of polyphenol-protein nanoparticles for relieving colitis |
-
2017
- 2017-06-16 CN CN201710461559.8A patent/CN107308042A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753403A (en) * | 2017-11-28 | 2018-03-06 | 湖南康麓生物科技有限公司 | A kind of natural nutrition moisture saver mask and preparation method thereof |
| CN112690452A (en) * | 2021-01-13 | 2021-04-23 | 中国热带农业科学院海口实验站 | Preparation method of polyphenol-protein nanoparticles for relieving colitis |
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