CN106963986A - 脂肪干细胞‑ecm修饰sis复合工程骨及其制备方法 - Google Patents
脂肪干细胞‑ecm修饰sis复合工程骨及其制备方法 Download PDFInfo
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- CN106963986A CN106963986A CN201710031655.9A CN201710031655A CN106963986A CN 106963986 A CN106963986 A CN 106963986A CN 201710031655 A CN201710031655 A CN 201710031655A CN 106963986 A CN106963986 A CN 106963986A
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- cell
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3847—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201710031655.9A CN106963986B (zh) | 2017-01-17 | 2017-01-17 | 脂肪干细胞-ecm修饰sis复合工程骨及其制备方法 |
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CN201710031655.9A CN106963986B (zh) | 2017-01-17 | 2017-01-17 | 脂肪干细胞-ecm修饰sis复合工程骨及其制备方法 |
Publications (2)
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CN106963986A true CN106963986A (zh) | 2017-07-21 |
CN106963986B CN106963986B (zh) | 2020-05-26 |
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CN201710031655.9A Active CN106963986B (zh) | 2017-01-17 | 2017-01-17 | 脂肪干细胞-ecm修饰sis复合工程骨及其制备方法 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107929817A (zh) * | 2017-12-01 | 2018-04-20 | 蒋文明 | 一种可降解血管支架材料的制备方法 |
CN110257335A (zh) * | 2019-04-10 | 2019-09-20 | 首都医科大学附属北京天坛医院 | 单层或多层的3d脑胶质瘤细胞培养模型及其构建方法和应用 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070014773A1 (en) * | 2005-07-15 | 2007-01-18 | Matheny Robert G | Compositions for regenerating defective or absent myocardium |
CN101002967A (zh) * | 2006-12-27 | 2007-07-25 | 重庆大学 | 成体干细胞覆膜血管内支架及制备方法 |
CN101361989A (zh) * | 2008-09-03 | 2009-02-11 | 陕西瑞盛生物科技有限公司 | 双层膜状组织修补材料及其制备方法 |
CN101361990A (zh) * | 2008-09-03 | 2009-02-11 | 陕西瑞盛生物科技有限公司 | 一种双层人工皮肤及其制备方法 |
CN101366977A (zh) * | 2008-09-03 | 2009-02-18 | 陕西瑞盛生物科技有限公司 | 具有生物活性的组织修补材料及其制备方法 |
CN104874024A (zh) * | 2015-05-20 | 2015-09-02 | 宁波大学 | 细胞组装小肠黏膜下层仿生复合工程骨及其制备方法 |
CN105126171A (zh) * | 2015-08-27 | 2015-12-09 | 中国人民解放军第三军医大学 | 一种具有形状记忆功能的凝胶生物材料及其制备方法 |
US20150352145A1 (en) * | 2006-01-18 | 2015-12-10 | CorMartix Cardiovascular, Inc. | Method and System for Treatment of Damaged Biological Tissue |
-
2017
- 2017-01-17 CN CN201710031655.9A patent/CN106963986B/zh active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070014773A1 (en) * | 2005-07-15 | 2007-01-18 | Matheny Robert G | Compositions for regenerating defective or absent myocardium |
US20150352145A1 (en) * | 2006-01-18 | 2015-12-10 | CorMartix Cardiovascular, Inc. | Method and System for Treatment of Damaged Biological Tissue |
CN101002967A (zh) * | 2006-12-27 | 2007-07-25 | 重庆大学 | 成体干细胞覆膜血管内支架及制备方法 |
CN101361989A (zh) * | 2008-09-03 | 2009-02-11 | 陕西瑞盛生物科技有限公司 | 双层膜状组织修补材料及其制备方法 |
CN101361990A (zh) * | 2008-09-03 | 2009-02-11 | 陕西瑞盛生物科技有限公司 | 一种双层人工皮肤及其制备方法 |
CN101366977A (zh) * | 2008-09-03 | 2009-02-18 | 陕西瑞盛生物科技有限公司 | 具有生物活性的组织修补材料及其制备方法 |
CN104874024A (zh) * | 2015-05-20 | 2015-09-02 | 宁波大学 | 细胞组装小肠黏膜下层仿生复合工程骨及其制备方法 |
CN105126171A (zh) * | 2015-08-27 | 2015-12-09 | 中国人民解放军第三军医大学 | 一种具有形状记忆功能的凝胶生物材料及其制备方法 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107929817A (zh) * | 2017-12-01 | 2018-04-20 | 蒋文明 | 一种可降解血管支架材料的制备方法 |
CN110257335A (zh) * | 2019-04-10 | 2019-09-20 | 首都医科大学附属北京天坛医院 | 单层或多层的3d脑胶质瘤细胞培养模型及其构建方法和应用 |
CN110257335B (zh) * | 2019-04-10 | 2020-09-29 | 首都医科大学附属北京天坛医院 | 单层或多层的3d脑胶质瘤细胞培养模型及其构建方法和应用 |
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Publication number | Publication date |
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CN106963986B (zh) | 2020-05-26 |
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Application publication date: 20170721 Assignee: Ningbo Yongben Technology Co.,Ltd. Assignor: Ningbo University Contract record no.: X2022980025293 Denomination of invention: SIS composite engineered bone modified by adipose stem cells ECM and its preparation method Granted publication date: 20200526 License type: Common License Record date: 20221207 |
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Effective date of registration: 20230117 Address after: 401120 No.107 dataguzhong Road, Xiantao street, Yubei District, Chongqing Patentee after: Chongqing supersonic Intellectual Property Operation Co.,Ltd. Address before: 315211, Fenghua Road, Jiangbei District, Zhejiang, Ningbo 818 Patentee before: Ningbo University Effective date of registration: 20230117 Address after: 450000 1st floor, building 11, Zhengzhou Hengfeng scientific innovation center, intersection of Xingang 7th road and Meihe East Road, HANGGANG District, Zhengzhou City, Henan Province Patentee after: Henan Yuanchuang life stem cell bank technology Co.,Ltd. Patentee after: Zhengzhou Yuanchuang Gene Technology Co.,Ltd. Address before: 401120 No.107 dataguzhong Road, Xiantao street, Yubei District, Chongqing Patentee before: Chongqing supersonic Intellectual Property Operation Co.,Ltd. |