CN106963837A - Skin trauma nursing essential oil and its preparation method and application - Google Patents

Skin trauma nursing essential oil and its preparation method and application Download PDF

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CN106963837A
CN106963837A CN201710377551.3A CN201710377551A CN106963837A CN 106963837 A CN106963837 A CN 106963837A CN 201710377551 A CN201710377551 A CN 201710377551A CN 106963837 A CN106963837 A CN 106963837A
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廖建军
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

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Abstract

The invention provides a kind of skin trauma nursing essential oil and its preparation method and application, belong to essential oil field.A kind of skin trauma nurses essential oil, and it is formed by base oil and a variety of folk prescription essential oils compounding, is counted by weight, 20~200 parts of base oil;Folk prescription essential oil includes 1~10 part of 1~10 part of sweet orange oil, 1~10 part of tea tree ethereal oil, 1~10 part of chamomile essential oil and Lavender.A kind of skin trauma nurses the preparation method of essential oil, and folk prescription essential oil is well mixed in base oil.Four kinds of folk prescription essential oils are placed in base oil by the present invention carries out the skin trauma nursing essential oil that mediation forms high concentration, and good therapeutic action can be played to the skin that is wound, and will not produce red swelling of the skin and situation about burning, to no skin irritation and toxic side effect.In addition, a kind of skin trauma that the present invention is provided nurses application of the essential oil in skin trauma or burn, the application of essential oil is expanded.

Description

Skin trauma nursing essential oil and its preparation method and application
Technical field
The present invention relates to essential oil field, nurse essential oil and preparation method thereof in particular to a kind of skin trauma and answer With.
Background technology
Scar is the outward appearance phychology and the general designation of tissue pathologies change of caused normal skin tissue after various wounds, It is the inevitable outcome in human body processes of wound repair.Scar growth exceedes certain limit, will occur various complication, all The destruction of such as profile and functional activity obstacle, huge human body pain and mental suffering is brought to patient, especially burns, scald The scar left after wound, severe trauma.The main method that existing medical means eliminate scar is chemotherapy, radiotherapy, swashed Light therapy, skin grind the art etc. that disappears, but these method curative effects are poor, and cost is higher, and easily recurrence.
The content of the invention
The first object of the present invention is to provide a kind of skin trauma nursing essential oil, its can antibacterial, antibacterial, and with only Bitterly, calm effect, helps patient to recover elasticity of skin, eliminates the place's scar that is wound.
The second object of the present invention is to provide the preparation method that a kind of skin trauma nurses essential oil, and this method is simple, behaviour Make easy, feasibility is strong.
The third object of the present invention is to provide a kind of application of skin trauma nursing essential oil in skin trauma or burn.
The present invention is solved its technical problem and realized using following technical scheme.
A kind of skin trauma nurses essential oil, and it is formed by base oil and a variety of folk prescription essential oils compounding, is counted by weight, 20~200 parts of base oil;A variety of folk prescription essential oils include 1~10 part of sweet orange oil, 1~10 part of tea tree ethereal oil, chamomile essential oil 1~ 10 parts and 1~10 part of Lavender.
A kind of skin trauma nurses the preparation method of essential oil, it is characterised in that by sweet orange oil, tea tree ethereal oil, chamomile Essential oil and Lavender are well mixed with base oil.
A kind of application of skin trauma nursing essential oil in the medicine as skin trauma or burn.
A kind of beneficial effect of skin trauma that the present invention is provided nursing essential oil and its preparation method and application is:The present invention The skin trauma nursing essential oil of offer is counted including 20~200 parts of base oil, 1~10 part of sweet orange oil, tea tree essence by weight 1~10 part of 1~10 part of oil, 1~10 part of chamomile essential oil and Lavender.Compound to form height by base oil and folk prescription essential oil The skin trauma nursing essential oil of concentration, can effectively play antibacterial, antibacterial, repair the effect of damaged skin, wherein, sweet orange oil There is good effect for the growth and reparation of bodily tissue, collagen can be helped to be formed, while compounding has purification work( The tea tree ethereal oil of energy and treat wound suppuration function so that the skin that is wound is easier to recover, Lavender and chamomile essential oil Patient can be helped to keep gentle phychology, at the same can reduction of patient be wound the pain at place, beneficial to treatment.The present invention is by sweet tea Orange essential oil, tea tree ethereal oil, four kinds of folk prescription essential oils of chamomile essential oil and Lavender, which are placed in base oil reconcile, forms high The skin trauma nursing essential oil of concentration, can fully reconcile the special natures of various folk prescription essential oils, complement each other simultaneously, mutually association Together, the skin trauma nursing essential oil of high concentration can play good therapeutic action to the skin that is wound, and will not produce red swelling of the skin With situation about burning, above-mentioned medicine plants essential oil is that pure plant extracts essential oil, stingless to skin without any chemical synthesis composition Swash property and toxic side effect.In addition, the preparation method of skin trauma nursing essential oil is simple, obtained skin trauma nurses essential oil energy Good therapeutic action is played to the skin that is wound.The skin trauma is nursed to essential oil as medicinal application in skin trauma or burn In, expand the application of essential oil.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, are the conventional production that can be obtained by commercially available purchase Product.
Essential oil is nursed to a kind of skin trauma of the embodiment of the present invention below and the skin trauma nurses the preparation side of essential oil The application of method and skin trauma nursing essential oil in skin trauma or burn is specifically described.
A kind of skin trauma nurses essential oil, and it is formed by base oil and a variety of folk prescription essential oils compounding.According to parts by weight Meter, 20~200 parts of base oil;A variety of folk prescription essential oils include 1~10 part of sweet orange oil, 1~10 part of tea tree ethereal oil, chamomile essential oil 1~10 part and 1~10 part of Lavender.
In the embodiment of the present invention, one or more of the base oil in SIMMONDSIA CHINENSIS SEED OIL, evening primrose oil, pot marigold essential oil. SIMMONDSIA CHINENSIS SEED OIL, evening primrose oil, pot marigold essential oil have volatility weak, and do not hinder the characteristic of the volatilization of medicine plants essential oil, it is to avoid The danger brought in the prior art using volatile solvents such as ethanol, isopropanols.
Wherein, SIMMONDSIA CHINENSIS SEED OIL is the combination of a kind of alcohol polymer and aliphatic acid, and the stabilization of its textural anomaly will not be high Temperature destruction, SIMMONDSIA CHINENSIS SEED OIL is highly stable.
The composition of evening primrose oil is γ~linolenic acid, magnesium, zinc, injection Vitamin B_6, B6 and niacin.Original producton location Britain, 100% pure natural evening primrose oil, is to take the squeezing of its seed is refined to form.To preventing skin early ageing, helping nail development, solution head Skin problem, peculiar smell atopic dermatitis, wound healing, psoriasis, eczema, climacteric, angiocardiopathy are helpful.
Pot marigold essential oil, the 100% pure natural pot marigold oil in Britain's import original producton location, is via senior CO2Extraction essence System is formed.It is helpful to whelk, skin frostbite, diaper rash, skin scar, varication and scratch.
Preferably, from oily based on single SIMMONDSIA CHINENSIS SEED OIL, using oily based on SIMMONDSIA CHINENSIS SEED OIL, not only play The effect of above-mentioned a variety of medicine plants essential oils is diluted, while can also promote the trap of skin.SIMMONDSIA CHINENSIS SEED OIL is that permeability is most strong Grease.In addition its stability is high, can be resistant to strong light, high temperature and holding structure is constant, the peace of high temperature generation can be effectively prevented from Full problem.
Sweet orange oil, due in sweet orange contain substantial amounts of Vc, can preventing cold, growth and reparation for bodily tissue have Good effect, can promote sweating, thus the skin blocked can be helped to discharge toxin, to oiliness, dark sore or dry skin person all It is helpful.In addition, sweet orange oil can also balance skin pH-value, have moistening effect to skin, help collagen to be formed, mend Water whitening, desalinates microgroove, and the skin for the patient that helps to be wound recovers.
Tea tree ethereal oil, with bactericidal antiphlogistic, convergence pore, treatment suppurative wound and burn, tan severely, athlete's foot and dandruff. Its clean-up effect is excellent, can be effectively improved the suppuration phenomenon of wound infection caused by skin trauma, removes varicella and banding blister Small pox caused by rash and unclean position.Can be applied to burn, sore, sunburn, tinea, wart, tinea circinata and bleb.
Chamomile essential oil distill from flower, pacified and sedation effect with splendid, can alleviate anxiety, anxiety, indignation with Fear, contributes to the patient's mental state for making skin be wound gentle, beneficial to treatment.Chamomile essential oil also has treatment and makes skin simultaneously The effect of regeneration, because chamomile can stimulate the manufacture of white blood cell, and then resists bacterium, strengthens immune system, therefore make For skin, gentle rubescent, dry and allergy the skin problem of energy, for sensitivity, eczema, psoriasis and other various decortications Skin problem is also effective.And lasting infection can be improved, patient is prevented effectively from and is infected because skin is wound.It can be used In treatment acne, eczema, fash, wound, dermatitis, drying and the skin itched, and general allergic condition.It is various treating The curative effect that the inflammation of type has had.
Lavender has extremely strong penetrating power, can rapidly enter the bacterial eradication of lower 240 microns of skin, thoroughly The skin problems such as whelk caused by bacteria breed under skin, hair follicle are blocked, acne, blackhead, pore be thick are removed, in flesh Skin skin corium formation diaphragm, resists bacterium and grows again.In addition, Lavender can it is calm, relieve pain, pacify, be conducive to The phychology for the patient that gentle skin is wound, the pain at place while reduction of patient is wound, lavender also has nourishing, eliminates scar Effect, can effectively nourish and protection is wound place's skin, recover elasticity of skin, elimination is wound place's scar.
Preferably, count by weight, 60~128 parts of base oil, a variety of folk prescription essential oils include 3~8 parts of sweet orange oil, ocean 3~8 parts of 3~8 parts of camomile essential oil, 3~8 parts of tea tree ethereal oil and Lavender.
It is highly preferred that count by weight, 80~120 parts of base oil, a variety of folk prescription essential oils only by 4~6 parts of sweet orange oil, 4~6 parts of chamomile essential oil, 4~6 parts of compositions of 4~6 parts of tea tree ethereal oil and Lavender.It that is to say, in the optimal implementation of invention In example, the raw material of skin trauma nursing essential oil has and only 80~120 parts of base oil, and a variety of folk prescription essential oils are only by sweet orange oil 4 4~6 parts of~6 parts, 4~6 parts of chamomile essential oil, 4~6 parts of tea tree ethereal oil and Lavender are constituted.
Certainly, in other embodiments, folk prescription essential oil count by weight can also include 1~10 part of frankincense essential oil and/ Or 1~10 part of deodar essential oil.
The extraction of frankincense essential oil distributes warm pure wooden fragrance, light fruity is appeared again, its energy from olibanum resin Enough pacify patient, and can make patient loosen mood and releive irritability situations such as, in addition, frankincense essential oil can also recover skin bullet Property, pore is tightened up, improves relaxation, it is effective to wound, wound, ulcer and inflammation.
Deodar essential oil has significant antiinflammation, antibacterial, convergence, softness, killing fungus.So pimples and acne can be improved Skin, while scab caused by skin trauma, purulence and some chronic diseases can be eliminated.
Preferably, frankincense essential oil and deodar essential oil, which are combined, is added in base oil, and frankincense essential oil and the mediation of deodar essential oil make With, can obvious softening skin, damaged skin is recovered elasticity and gloss.
It that is to say, skin trauma nursing essential oil provided in an embodiment of the present invention can be only by base oil, sweet orange oil, tea tree Essential oil, chamomile essential oil and Lavender compounding use, frankincense essential oil and deodar essential oil can also be compounded again on this basis.
It should be noted that Lavender includes alcohols, esters, ketone and many oxide;In chamomile essential oil Containing esters, many oxide and alkene;Tea tree ethereal oil contains many oxide;Sweet orange also contains alkene.Essential oil containing alcohols have refresh oneself, Anti-corrosion, antiviral effect;Essential oil containing esters have pacify, calm, balance, corrosion-resistant effect;Essential oil containing ketone has reduction Mucous secretion and the effect for curing scar tissue;Oxycompound class essential oil can treat respiratory problems;And essential oil containing alkenes Effect with antiviral, anti-corrosion, anti-inflammation and sterilization.In the present embodiment, the essential oil of a variety of heterogeneity contents is reconciled and used, and Reconciled in the range of specific parts by weight, obtained skin trauma nursing essential oil has effect of a variety of essential oils concurrently, while a variety of Composition cooperates, mutually collaboration, is conducive to strengthening pacifying, the effect of antibacterial, the recovery for the skin that is more beneficial for being wound.
It is not that simple mixing is matched somebody with somebody according to obtained by inventor's creative experiments that the selection of the parts by weight of above-mentioned raw materials, which is, Than.It should be noted that the selection of the parts by weight of above-mentioned raw materials also needs the parts by weight for meeting all folk prescription essential oils to account for base The 20~30% of the parts by weight of plinth oil, it is preferable that the parts by weight of all folk prescription essential oils account for the parts by weight of base oil 20~25%, it is highly preferred that the parts by weight of all folk prescription essential oils account for the 20% of the parts by weight of base oil.
It is well known that folk prescription essential oil is essential ingredient, one obtained by a kind of whole strain from plant or the extraction of some position As there is more strong this plant scent, and with specific effect and characteristics of personality.Folk prescription essential oil is simple one kind Plants essential oil, usually 100% purity, it is impossible to be used directly on skin, be typically added in cosmetics, will generally be adjusted with base oil Conjunction could use, if not diluted folk prescription essential oil is directly used in into skin, will skin ambustion, make red swelling of the skin, itch Etc. symptom.
In the prior art, folk prescription essential oil and base oil are compounded, the concentration that folk prescription essential oil accounts for base oil is 1~5%, and this In embodiment, the concentration that folk prescription essential oil accounts for base oil is 20~30%, therefore the concentration of obtained skin trauma nursing essential oil is remote It is more than the concentration of compounding essential oil of the prior art.In the prior art, the relatively low essential oil of compounding concentration primarily serves the work(of skin care Effect, without possessing treatment skin trauma or repairing effect of scar.Inventor is through long-term research and experiment, it was demonstrated that specific single The compounding of square essential oil can have effects that antibacterial, antibacterial, repair damaged skin and treatment skin trauma under a high concentration condition. Therefore, the composition and proportioning of the skin trauma nursing essential oil that the present embodiment is provided overcome the prejudice of prior art, are essential oil Using there is provided wider array of thinking and direction.
In addition, the embodiments of the invention provide the preparation method that a kind of skin trauma nurses essential oil, it is by folk prescription essential oil It is well mixed in base oil.The preparation method is simple, by mixing, a variety of essential oils is mixed, various essential oils can be played Effect, to reach the effect of compounding and stiffening effect.
The embodiment of the present invention additionally provides application of the above-mentioned skin trauma nursing essential oil in skin trauma or burn.
The treatment difficult point of burn is scalded in treatment at present, the skin after mainly being lost to epidermis carries out physics heat lamp irradiation, makes Epidermis liquorrhea goes out solidification and forms separation layer protection, sets up the condition of skin growth, this process is because of damaged area and degree meeting The long time is formed, the pain that the wounded still suffers from the long period is also resulted in, and uses essential oil to nurse basic 24 hours Left and right (used on the de- epidermal skin of wiping of 10 cm areas with regard to body fluid can be allowed to ooze out stopping, and was smearing this essence at present After oil 2 hours or so rear body fluid ooze out stop and initially form incrustation layer), and formed incrustation re-established favorably to skin growth Condition, effectively reduces the pain of the wounded and reduces infection risk.
It should be noted that the skin trauma nursing essential oil that the present embodiment is provided easily is influenceed by light, temperature, air, So preserve skin trauma nursing essential oil should be noted that it is following some:
1. container has safe water dropper, bottle cap is tightened using dark glass bottle.
2. it must be dried using rear bottleneck bottle cap, it is otherwise oxidizable rotten.
3. camomile class essential oil, which runs into low temperature, can produce cloud flaky crystal, it can recover normal if normal temperature is recovered.
4. Rosa Damascana can be crystallized at less than 16 DEG C, the thread crystallization such as feather is produced, belongs to normal condition.
5. chamomile has photosensitized reaction and special fragile chemical element, summer should be stored in refrigerator, taken with first 1 hour Go out.
6. the banksia rose class essential oil such as santal is deposited more fragrant and more fragrant without the shelf-life.
7. the fruits such as lemon, sweet orange, lavender, flower class essential oil, tanginess when such as buying is muddy then show to be possible to Through rotten.
8. the essential oil shelf-life do not broken a seal is 3~10 years, behind Kaifeng, it can be 2 years to preserve the preferable time limit, compound Kaifeng The shelf-life is 1 year afterwards.
The feature and performance to the present invention are described in further detail with reference to embodiments:
Embodiment one
The formula for the skin trauma nursing essential oil that the present embodiment is provided is as follows:(preparing 10ml altogether)
Base oil:20 parts of SIMMONDSIA CHINENSIS SEED OIL
Folk prescription essential oil:1 part of sweet orange oil, 1 part of tea tree ethereal oil, 1 part of chamomile essential oil, 1 part of Lavender.
Preparation method:By above-mentioned folk prescription essential oil:1 part of sweet orange oil, 1 part of tea tree ethereal oil, 1 part of chamomile essential oil, lavender 1 part of essential oil is placed in 20 parts of SIMMONDSIA CHINENSIS SEED OIL and is well mixed.Obtained skin trauma nursing essential oil can be applied to skin trauma or burning Wound, plays a part of repairing skin.
Embodiment two
The formula for the skin trauma nursing essential oil that the present embodiment is provided is as follows:(preparing 100ml altogether)
Base oil:80 parts of SIMMONDSIA CHINENSIS SEED OIL
Folk prescription essential oil:4 parts of sweet orange oil and 4 parts of tea tree ethereal oil, 4 parts of chamomile essential oil, 4 parts of Lavender.
Embodiment three
The formula for the skin trauma nursing essential oil that the present embodiment is provided is as follows:(preparing 10ml altogether)
Base oil:60 parts of SIMMONDSIA CHINENSIS SEED OIL
Folk prescription essential oil:3 parts of sweet orange oil, 3 parts of tea tree ethereal oil, 8 parts of chamomile essential oil, 3 parts of Lavender.
Example IV
The formula for the skin trauma nursing essential oil that the present embodiment is provided is as follows:(preparing 10ml altogether)
Base oil:128 parts of SIMMONDSIA CHINENSIS SEED OIL
Folk prescription essential oil:8 parts of sweet orange oil, 8 parts of tea tree ethereal oil, 3 parts of chamomile essential oil, 8 parts of Lavender and frankincense essence 1 part of oil.
Embodiment five
The formula for the skin trauma nursing essential oil that the present embodiment is provided is as follows:(preparing 10ml altogether)
Base oil:20 parts of 60 parts of SIMMONDSIA CHINENSIS SEED OIL and evening primrose oil
Folk prescription essential oil:4 parts of sweet orange oil, 4 parts of tea tree ethereal oil, 4 parts of chamomile essential oil, 4 parts of Lavender and deodar essence 4 parts of oil.
Embodiment six
The formula for the skin trauma nursing essential oil that the present embodiment is provided is as follows:(preparing 10ml altogether)
Base oil:20 parts of 130 parts of SIMMONDSIA CHINENSIS SEED OIL, 50 parts of evening primrose oil and pot marigold essential oil.
Folk prescription essential oil:6 parts of sweet orange oil, 6 parts of tea tree ethereal oil, 6 parts of chamomile essential oil, 6 parts of Lavender, frankincense essential oil 10 parts and 10 parts of deodar essential oil.
The skin trauma nursing essential oil provided for embodiment one is subjected to sterilization rate experiment, skin irritation test below And analysis of cases.
First, sterilization rate is determined
Escherichia coli, staphylococcus aureus, MRSE etc. be inoculated on MH Solid agar culture flat boards in 37 DEG C are cultivated 18~24 hours, are scraped lawn, are adjusted with physiological saline to 5.0 × 107~5.0 × 108cfu/ml;Candida albicans Bacterium is inoculated on sabouraud's agar flat board to be cultivated 18~24 hours in 37 DEG C, is scraped lawn, is adjusted with physiological saline to 5.0 ×107~5.0 × 108cfu/ml。
The skin trauma nursing essential oil that appropriate embodiment one is provided is taken, two-fold dilution is shaken with pure water.In 2.5ml MH meat The essential oil dilution of 2.5ml various concentrations is added in soup culture medium or Sharpe broth bouillon.And 0.1ml bacterium solutions are added, shake up, In 30~37 DEG C cultivate 24h after take 0.2ml to be applied on corresponding flat board, flat board in 30~37 DEG C cultivate 2 days, not long bacterium i.e. For minimal inhibitory concentration (MIC), continue to cultivate more than 3d, such as still not long bacterium is minimum bactericidal concentration (MBC), and draw and go out Bacterium rate, experimental result can be found in table 2.
The skin trauma of table 2. nurses essential oil sterilization rate experimental result table
From the above results, skin trauma nursing essential oil has stronger killing effect to most of mushrooms.
2nd, skin irritation test
Japan large ear rabbit 18, male and female half and half adapt to environment and 3 groups, every group 6, i.e. blank control are randomly divided into after 3 days Group, experimental group, contrast groups 1, contrast groups 2, contrast groups 3 and contrast groups 4.In 24h before experiment in the first cropping of back part of animal and both sides Afterwards with 8% vulcanized sodium depilation, 3 × 3cm2, keep skin complete.Each group uniformly smears administration 1ml/ only, and with antiseptic gauze and thoroughly Gelatin band is fixed, and blank group smears physiological saline 1ml/ only, and experimental group smears the skin trauma nursing essential oil that embodiment one is provided, Contrast groups 1 smear the compounding essential oil of the low concentration (3%) of identical component;Contrast groups 2 smear the ultrahigh concentration of identical component (40%) compounding essential oil;Contrast groups 3 smear the folk prescription in the compounding essential oil of the high concentration (15%) of heterogeneity, contrast groups 3 Essential oil includes:Sweet orange oil;Contrast groups 4 smear the folk prescription in the compounding essential oil of the high concentration (20%) of heterogeneity, contrast groups 4 Essential oil includes:Sweet orange oil, tea tree ethereal oil, chamomile essential oil, Lavender, frankincense essential oil, deodar essential oil and Pogostemon cablin essence Oil.
Then animal single cage is raised.Smear and tested material removed after medicine 24h, and observe rabbit off hair-fields medicine-feeding part 1, 24th, 48, situations such as whetheing there is erythema and oedema visually observed within 72 hours, and carries out statistical analysis.Skin irritation standards of grading And evaluation criterion is as follows, score value is stimulated:(erythematous response total score+oedema reaction total score)/number of animals.Stimulate score value<0.5 is stingless Swash;<3 be slight stimulation;<6 be that moderate is stimulated;>6 be that intensity is stimulated.Experimental data refers to table 3:
The skin irritation appraisal result of the compounding essential oil of the various concentrations of table 3. and different component
The above results show that the skin trauma nursing essential oil of selection is non-stimulated to skin, but be made from other components High concentration compounding essential oil has stronger stimulation to skin, easily causes erythema and oedema, causes skin burn, therefore, the present invention Specific component (sweet orange oil, tea tree ethereal oil, chamomile essential oil, Lavender, frankincense essential oil, deodar that embodiment is selected Essential oil) (20~30%) are non-stimulated to skin in specific concentration range, and other components, other concentration or identical group Other concentration divided, can have certain damage to skin.
3rd, case:
Female:77 years old;Ulcer between toe, the ulcer of diabetes patient is not easy the situation of healing, and this implementation is used at the place of being wound The skin trauma nursing essential oil that example 5 is provided, starts incrustation for second day after use.
Man:47 years old;Using scratching fingers during instrument, the skin trauma provided at the place of being wound using the present embodiment 5 nurses essence Oil, starts incrustation, no redness suppuration infection phenomenons, wound healing after five days for second day after use.
Female:45 years old;Bubble is burnt when moxa-moxibustion is done in traditional Chinese medical science shop, doctor, which says, to be punctured, is afraid of that infection allows spontaneous regression, by The skin trauma provided at wound using the present embodiment 5 nurses essential oil, punctures and essential oil, after use second day are directly smeared after bubble Start incrustation, it is noninductive incarnadine it is swollen, using after one week healing incrustation nature come off.
In summary, the skin trauma nursing essential oil that the present invention is provided is counted including 20~200 parts of base oil by weight, 1~10 part of 1~10 part of sweet orange oil, 1~10 part of tea tree ethereal oil, 1~10 part of chamomile essential oil and Lavender.By basis Oil compounds the skin trauma nursing essential oil to form high concentration with folk prescription essential oil, can effectively play antibacterial, antibacterial, repair impaired skin The effect of skin, wherein, sweet orange oil has good effect for the growth and reparation of bodily tissue, can help collagen shape Into while tea tree ethereal oil of the compounding with purification function and treat wound suppuration function so that the skin that is wound is easier to recover, and smokes Clothing grass essential oil and chamomile essential oil can help patient to keep gentle phychology, at the same can reduction of patient be wound the pain at place Sense, beneficial to treatment.Sweet orange oil, tea tree ethereal oil, four kinds of folk prescription essential oils of chamomile essential oil and Lavender are placed in by the present invention Carry out reconciling the skin trauma nursing essential oil for forming high concentration in base oil, can fully reconcile the particularity of various folk prescription essential oils Matter, complements each other simultaneously, mutually collaboration, and the skin trauma nursing essential oil of high concentration can play good treatment to the skin that is wound and make With, and red swelling of the skin and situation about burning will not be produced, above-mentioned medicine plants essential oil is that pure plant extracts essential oil, without anyization Synthetic ingredient is learned, to no skin irritation and toxic side effect.In addition, the preparation method of skin trauma nursing essential oil is simple, system The skin trauma nursing essential oil obtained can play good therapeutic action to the skin that is wound.Skin trauma nursing essential oil is applied to In skin trauma or burn, the application of essential oil is expanded.
Embodiments described above is a part of embodiment of the invention, rather than whole embodiments.The reality of the present invention The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made Every other embodiment, belongs to the scope of protection of the invention.

Claims (10)

1. a kind of skin trauma nurses essential oil, it is characterised in that it is formed by base oil and a variety of folk prescription essential oils compounding, by weight Measure number meter, 20~200 parts of the base oil;A variety of folk prescription essential oils include 1~10 part of sweet orange oil, tea tree ethereal oil 1~ 1~10 part of 10 parts, 1~10 part of chamomile essential oil and Lavender.
2. skin trauma according to claim 1 nurses essential oil, it is characterised in that count by weight, the base oil 60~128 parts, a variety of folk prescription essential oils include 3~8 parts of the sweet orange oil, 3~8 parts of the chamomile essential oil, the tea Set 3~8 parts of essential oil and 3~8 parts of the Lavender.
3. skin trauma according to claim 1 nurses essential oil, it is characterised in that count by weight, the base oil 80~120 parts, a variety of folk prescription essential oils are only by 4~6 parts of the sweet orange oil, 4~6 parts of the chamomile essential oil, the tea Set 4~6 parts of compositions of 4~6 parts of essential oil and the Lavender.
4. skin trauma according to claim 1 nurses essential oil, it is characterised in that count by weight, the folk prescription essence Oil also includes 1~10 part of frankincense essential oil.
5. the skin trauma nursing essential oil according to claim 1 or 4, it is characterised in that count by weight, the folk prescription Essential oil also includes 1~10 part of deodar essential oil.
6. skin trauma according to claim 1 nurses essential oil, it is characterised in that the gross weight of a variety of folk prescription essential oils Number accounts for the 20~30% of the parts by weight of the base oil.
7. skin trauma according to claim 6 nurses essential oil, it is characterised in that the gross weight of a variety of folk prescription essential oils Number accounts for the 20~25% of the parts by weight of the base oil.
8. skin trauma according to claim 1 nurses essential oil, it is characterised in that the base oil be selected from SIMMONDSIA CHINENSIS SEED OIL, One or more in evening primrose oil, pot marigold essential oil.
9. a kind of skin trauma as described in any one of claim 1~8 nurses the preparation method of essential oil, it is characterised in that will The sweet orange oil, the tea tree ethereal oil, the chamomile essential oil and the Lavender are well mixed with the base oil.
10. a kind of skin trauma nursing essential oil as described in any one of claim 1~8 is being used as treatment skin trauma or burn Medicine in application.
CN201710377551.3A 2017-05-24 2017-05-24 Skin trauma nursing essential oil and its preparation method and application Pending CN106963837A (en)

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Publication number Priority date Publication date Assignee Title
CN107557164A (en) * 2017-10-10 2018-01-09 广东长利香精香料有限公司 A kind of lemongrass sweet orange oil
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