CN107496598A - Skin antibacterial liquid and preparation method thereof - Google Patents
Skin antibacterial liquid and preparation method thereof Download PDFInfo
- Publication number
- CN107496598A CN107496598A CN201710942003.0A CN201710942003A CN107496598A CN 107496598 A CN107496598 A CN 107496598A CN 201710942003 A CN201710942003 A CN 201710942003A CN 107496598 A CN107496598 A CN 107496598A
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- China
- Prior art keywords
- skin
- essential oil
- liquid according
- plant extracts
- parts
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Abstract
The present invention relates to skin sterilization product, more particularly to a kind of skin antibacterial liquid and preparation method thereof.The raw material of the skin antibacterial liquid includes 0.028 0.995 parts of plant extracts, 0.005 0.3 parts of thickener, 0.05 1.2 parts of emulsifying agent, 0.5 1.0 parts of nertralizer, one or more of the plant extracts in Lavender, mother chrysanthemum flower essential oil, honeysuckle essential oil, menthol, matrimony vine leaf extract by weight.Lavender, mother chrysanthemum flower essential oil, honeysuckle essential oil all have the function that sterilization, antibacterial in the present invention, can effectively remove the mushroom on skin.Meanwhile honeysuckle essential oil and matrimony vine leaf extract have raising body immunity, adjust immune effect.Moreover, Lavender has the function of promoting cytothesis.Triplicity, the cell tissue of affected area can be promoted to recover, eradicate focus, avoid skin disease repeatedly.
Description
Technical field
The present invention relates to skin sterilization product, more particularly to a kind of skin antibacterial liquid and preparation method thereof.
Background technology
Skin infection and cutaneous lesions can all cause skin disease, and wherein skin disease caused by skin infection is more common.Skin
Skin infection is mainly caused by bacterium or fungi, such as staphylococcus aureus, Escherichia coli and Candida albicans etc..Therefore, skin
It is general using sterilization, antibacterial treatment method in dermopathic clinical treatment caused by skin infection.Existing disinfection skin
In medicine, mainly disinfection composition is included.Killed by these effective sterilization components except bacterium in skin or fungi.It is bacterium, true
The generation of bacterium is normally due to the decline of personal resistance causes.Above-mentioned disinfection dermic is only killed except the mushroom of invasion, and
Focus can not be eradicated, therefore is easily produced repeatedly.
The content of the invention
It is an object of the invention to provide a kind of skin antibacterial liquid, except the inhibiting bacteria and diminishing inflammation of the antibacterial cream of general skin, antivirus is killed
Bacterium effect is outer, also have the function that it is clearing heat and detoxicating, reduce it is dermopathic repeatedly.
In order to achieve the above object, the present invention provides a kind of skin antiseptic liquid, includes the raw material of following parts by weight：
The plant extracts is selected from Lavender, mother chrysanthemum flower essential oil, honeysuckle essential oil, menthol, folium lycii extraction
One or more in thing.
The present invention passes through repetition test by realizing repeatedly, from bactericidal plant extracts, and screening obtains foregoing
Specific various composition.Specifically, Lavender can permeate hair follicle disinfecting, antimicrobial, promote cytothesis, recover skin
Connective tissue, while balance skin top layer fat secretion, play clearing heat and detoxicating, cleaning skin, control the effect of oil；Chrysanthemum indicum
Essential oil is inhibited to staphylococcus aureus, shigella dysenteriae, EHEC, typhoid bacillus etc.；And there are anti-inflammatory, antioxygen
Change, analgesic activities；The bioactivity of chlorogenic acid contained by honeysuckle essential oil, human metabolism, regulation bodily fuctions can be promoted, carried
High immunity, there is antibacterial, anti-inflammatory, adjust the effect such as immune；Menthol acts on skin or mucous membrane, there is refrigerant itching-relieving action,
Stimulate circulation；Matrimony vine leaf extract has facilitation to immunity, while has immunoregulation effect；To normal healthy people
Also there is notable effect in increasing leukocyte.
Preferably, the plant extracts specifically comprises (in parts by weight)：
In the present invention, Lavender, mother chrysanthemum flower essential oil, honeysuckle essential oil all have the function that sterilization, antibacterial, can
Effectively remove the mushroom on skin.Meanwhile honeysuckle essential oil and matrimony vine leaf extract have raising body immunity, regulation is immunized
Effect.Moreover, Lavender has the function of promoting cytothesis.Triplicity, the groups of cells of affected area can be promoted
Recovery is knitted, focus is eradicated, avoids skin disease repeatedly.
The selection of the thickener is not particularly limited, as long as disclosed in the prior art, to can apply to skin antibacterial
The thickener of liquid can be used.Preferably, specifically using carbomer resin as thickener.Carbomer resin is the third of crosslinking
Olefin(e) acid polymer, with regard to effective thickening power can be played under relatively low usage amount.
The emulsifying agent plays a part of promoting active ingredient to disperse, improves system stability.Preferably, specific use
Cremophor RH40 is as emulsifying agent.
The preferred triethanolamine of nertralizer, except the viscosity and stably that can be neutralized carbomer resin, improve antibacterial liquid
Outside property, triethanolamine also has itching-relieving action.
Further, one kind or more in NMF, bactericide or preservative is also included in skin antibacterial liquid of the invention
Kind.
The NMF is preferably 2.8-25.5 parts, is chosen in particular from the one or more of propane diols, glycerine, butanediol.
Propane diols has the characteristic of fat-soluble solvent, and permeability is very strong, and dissolving power is big；Cremophor RH40 combination propane diols, energy
Enough strengthen the solubilizing effect of Cremophor RH40, improve the uniformity of oily substance.Glycerine is glycerine, is conventional small
Molecule alcohols NMF.Butanediol is in addition to possessing moisture-keeping functions, also with certain bacteriostasis.Preferably, the guarantor
Humectant is propane diols, glycerine and butanediol, and three's consumption proportion (parts by weight) is：
Propane diols 0.1-2.5 parts
Glycerine 2.5-12 parts
Butanediol 0.2-11 parts.
The selection of the bactericide and preservative is not particularly limited.Angularly consider with the phase same sex from raw material is ready availability,
It is preferred that using Phenoxyethanol as bactericide, nipagin esters as preservative.
The present invention also provides a kind of preparation method of skin antibacterial liquid, comprises the following steps：
S1, plant extracts, thickener, emulsifying agent and water is well mixed；
S2, nertralizer is added into S1 mixture, be well mixed, obtain skin antibacterial liquid.
Further, the preparation method is additionally included in step S1, after step S1 or in step S2, is added and is protected
One or more in humectant, bactericide, preservative.
Further, the preparation method also includes
S3, by S2 skin antibacterial liquid it is filling, sterilizing and packaging.
Beneficial effects of the present invention are：
Lavender, mother chrysanthemum flower essential oil, honeysuckle essential oil all have the function that sterilization, antibacterial, can effectively go to allowance for bark
Mushroom on skin.Meanwhile honeysuckle essential oil and matrimony vine leaf extract have raising body immunity, adjust immune effect.And
And Lavender has the function of promoting cytothesis.Triplicity, the cell tissue of affected area can be promoted to recover, root
Except focus, skin disease is avoided repeatedly.Menthol can stimulate circulation, and improve the speed of cell metabolism, with it is above-mentioned into
Divide and produce synergy, promote cell to recover.
Embodiment
Technical scheme will be clearly and completely described below, it is clear that described embodiment is only
Part of the embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art
The every other embodiment obtained under the premise of creative work is not made, belongs to the scope of protection of the invention.
Embodiment 1
The composition and preparation method of skin antibacterial liquid shown in the present embodiment are as follows：
S1, plant extracts, carbomer resin 0.2g, Cremophor RH40 1g and water 15mL be well mixed；Institute
Plant extracts is stated as Lavender 0.2g, mother chrysanthemum flower essential oil 0.05g, honeysuckle essential oil 0.1g；
S2, triethylamine 1g is added into S1 mixture, be well mixed, obtain skin antibacterial liquid.
The present embodiment show the mild antibacterial liquid without menthol and matrimony vine leaf extract.
Embodiment 2
The composition and preparation method of skin antibacterial liquid shown in the present embodiment are as follows：
S1, plant extracts, carbomer resin 0.2g, Cremophor RH40 1g and water 10mL be well mixed；Institute
Plant extracts is stated as Lavender 0.05g, mother chrysanthemum flower essential oil 0.01g, honeysuckle essential oil 0.2g, menthol 0.02g, matrimony vine
Leaf extract 0.005g；
S2, triethylamine 0.5g is added into S1 mixture, be well mixed, obtain skin antibacterial liquid.
The present embodiment show representative formula.
Embodiment 3
The composition and preparation method of skin antibacterial liquid shown in the present embodiment are as follows：
S1, plant extracts, carbomer resin 0.1g, Cremophor RH40 0.15g and water 10mL be well mixed；
The plant extracts is Lavender 0.05g, mother chrysanthemum flower essential oil 0.01g, honeysuckle essential oil 0.2g, menthol 0.02g, Chinese holly
Qi leaf extract 0.005g；
S2, triethylamine 0.65g is added into S1 mixture, be well mixed；Glycerine 8g, butanediol 8g are added, is mixed
Close uniformly, obtain skin antibacterial liquid.
The present embodiment show humidity-preserving type formula.
Embodiment 4
The composition and preparation method of skin antibacterial liquid shown in the present embodiment are as follows：
S1, plant extracts, carbomer resin 0.1g, Cremophor RH40 0.15g and water 10mL be well mixed；
The plant extracts is Lavender 0.05g, mother chrysanthemum flower essential oil 0.01g, honeysuckle essential oil 0.2g, menthol 0.02g, Chinese holly
Qi leaf extract 0.005g；
S2, triethylamine 0.65g is added into S1 mixture, be well mixed；Add propane diols 2g, glycerine 8g, fourth
Glycol 6g, it is well mixed；Phenoxyethanol 0.2g, ethylparaben 0.2g are eventually adding, obtains skin antibacterial liquid.
S3, the skin antibacterial liquid for obtaining S2 are filling, sterilize and pack.
The present embodiment show a kind of production procedure of sales item of skin antibacterial liquid.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention described should be defined by scope of the claims.
Claims (10)
1. skin antiseptic liquid, it is characterised in that include the raw material of following parts by weight：
The plant extracts is in Lavender, mother chrysanthemum flower essential oil, honeysuckle essential oil, menthol, matrimony vine leaf extract
One or more.
2. skin antiseptic liquid according to claim 1, it is characterised in that in terms of parts by weight, the plant extracts bag
Include：
3. skin antiseptic liquid according to claim 1 or 2, it is characterised in that the thickener is carbomer resin.
4. skin antiseptic liquid according to claim 1 or 2, it is characterised in that the emulsifying agent is PEG-40 hydrogenated castors
Oil.
5. skin antiseptic liquid according to claim 1 or 2, it is characterised in that the nertralizer is triethanolamine.
6. skin antiseptic liquid according to claim 1 or 2, it is characterised in that the raw material of the skin antibacterial liquid also includes
One or more in NMF, bactericide or preservative.
7. skin antiseptic liquid according to claim 6, it is characterised in that the content of the NMF is 2.8-25.5 weight
Part.
8. skin antiseptic liquid according to claim 6, it is characterised in that the bactericide is Phenoxyethanol, the anti-corrosion
Agent is nipagin esters.
9. the preparation method of skin antibacterial liquid according to claim 1, it is characterised in that comprise the following steps：
S1, plant extracts, thickener, emulsifying agent and water is well mixed；
S2, nertralizer is added into S1 mixture, be well mixed, obtain skin antibacterial liquid.
10. preparation method according to claim 9, it is characterised in that the preparation method is additionally included in step S1, walked
After rapid S1 or in step S2, the one or more in addition NMF, bactericide, preservative.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710942003.0A CN107496598A (en) | 2017-10-11 | 2017-10-11 | Skin antibacterial liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710942003.0A CN107496598A (en) | 2017-10-11 | 2017-10-11 | Skin antibacterial liquid and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107496598A true CN107496598A (en) | 2017-12-22 |
Family
ID=60701206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710942003.0A Pending CN107496598A (en) | 2017-10-11 | 2017-10-11 | Skin antibacterial liquid and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107496598A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108938795A (en) * | 2018-09-10 | 2018-12-07 | 郁光雷 | The antibacterial spray of skin and its preparation process |
| CN108938796A (en) * | 2018-09-10 | 2018-12-07 | 郁光雷 | A kind of skin bacteriostatic gel and its preparation process |
| CN109498535A (en) * | 2018-12-12 | 2019-03-22 | 怀化五零三侗医药科技开发有限公司 | Bacteria inhibiting composition, antibacterial disposable gel and its preparation method and application |
| CN110771634A (en) * | 2019-08-30 | 2020-02-11 | 安徽唐人药业有限公司 | Preparation method of clothing disinfection spray |
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|---|---|---|---|---|
| KR20120097903A (en) * | 2011-02-25 | 2012-09-05 | 애경산업(주) | Cosmetic composition having skin whitening and wrinkle improving activity |
| CN102755275A (en) * | 2012-07-24 | 2012-10-31 | 河南华美生物工程有限公司 | Dry cleaning and disinfecting gelatin prepared by using plant extracts |
| CN106860175A (en) * | 2017-03-28 | 2017-06-20 | 佛山市汇汾化妆品科技有限公司 | A kind of inhibiting bacteria and diminishing inflammation mildy wash |
-
2017
- 2017-10-11 CN CN201710942003.0A patent/CN107496598A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120097903A (en) * | 2011-02-25 | 2012-09-05 | 애경산업(주) | Cosmetic composition having skin whitening and wrinkle improving activity |
| CN102755275A (en) * | 2012-07-24 | 2012-10-31 | 河南华美生物工程有限公司 | Dry cleaning and disinfecting gelatin prepared by using plant extracts |
| CN106860175A (en) * | 2017-03-28 | 2017-06-20 | 佛山市汇汾化妆品科技有限公司 | A kind of inhibiting bacteria and diminishing inflammation mildy wash |
Non-Patent Citations (1)
| Title |
|---|
| 张玮等: "枸杞叶、桑叶水提物体外抑菌活性研究", 《包头医学院学报》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108938795A (en) * | 2018-09-10 | 2018-12-07 | 郁光雷 | The antibacterial spray of skin and its preparation process |
| CN108938796A (en) * | 2018-09-10 | 2018-12-07 | 郁光雷 | A kind of skin bacteriostatic gel and its preparation process |
| CN109498535A (en) * | 2018-12-12 | 2019-03-22 | 怀化五零三侗医药科技开发有限公司 | Bacteria inhibiting composition, antibacterial disposable gel and its preparation method and application |
| CN109498535B (en) * | 2018-12-12 | 2021-10-26 | 怀化五零三侗医药科技开发有限公司 | Bacteriostatic composition, bacteriostatic no-wash gel, and preparation method and application thereof |
| CN110771634A (en) * | 2019-08-30 | 2020-02-11 | 安徽唐人药业有限公司 | Preparation method of clothing disinfection spray |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171222 |
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| RJ01 | Rejection of invention patent application after publication |