CN104666496B - A kind of menthol ointment and its preparation technology - Google Patents

A kind of menthol ointment and its preparation technology Download PDF

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Publication number
CN104666496B
CN104666496B CN201510071443.4A CN201510071443A CN104666496B CN 104666496 B CN104666496 B CN 104666496B CN 201510071443 A CN201510071443 A CN 201510071443A CN 104666496 B CN104666496 B CN 104666496B
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parts
menthol
camphor
ointment
gaultherolin
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CN104666496A (en
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赵永国
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SHANGHAI ZHONGHUA PHARMACEUTICAL NANTONG Co Ltd
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SHANGHAI ZHONGHUA PHARMACEUTICAL NANTONG Co Ltd
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Abstract

The invention discloses menthol ointment, 150 170 parts of menthol is constituted by the raw material of following weight portion;90 110 parts of camphor;90 110 parts of gaultherolin;50 70 parts of volatile oil extracted from eucalyptus' leaves or twigs;90 110 parts of attar of rose;170 190 parts of paraffin;24 parts of ceresine;236 358 parts of albolene.The invention also discloses menthol ointment preparation technology.The product of the invention can be used to solve the problems, such as to prevent frostbite and pachylosis.With the effect that promoting blood circulation and removing blood stasis, clearing and activating the channels and collaterals, detumescence dispelling cold, antipruritic effect and promoting granulation, the healing of brothers' breach and wound are recovered, suitable for various degree pernio, it is red and swollen, itch, fester, with it is antifreeze, control jelly, detumescence, myogenic, antipruritic, crack arrest effect, it is that one kind can be adapted to used by the four seasons, winter can substitute the product of antifreeze frost.

Description

A kind of menthol ointment and its preparation technology
Technical field
The present invention relates to a kind of menthol ointment.
The invention further relates to a kind of menthol ointment preparation technology, more particularly to a kind of menthol ointment for preventing frostbite and pachylosis Preparation technology.
Background technology
Menthol ointment is off-white color or yellowish ointment, has aroma, there is refrigerant sense.For the nose caused by cold Plug, the symptomatic treatment of the disease such as insect bites and skin cracks.External application, cold is applied under nose, and insect bites, skin cracks are applied In affected part.Cold more or does not simultaneously have fever person for a long time, should not use this product, should arrive hospital therapy.
The all of cooling ointment of in the market, menthol ointment contain menthol, camphor, volatile oil extracted from eucalyptus' leaves or twigs;With refrigerant, antipruritic, prevention wound The effects such as wind is caught a cold, is seasonal product, be not suitable for the four seasons own, antifreeze white product can not be substituted.
Accordingly, it is desirable to provide a kind of new technical scheme solves the above problems.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of menthol ointment that can prevent frostbite and pachylosis problem.
The technical problem that the present invention also needs to solve is to provide a kind of preparation technology of above-mentioned menthol ointment.
In order to solve the above technical problems, the menthol ointment that a kind of present invention production four seasons can use, the technical scheme of use It is as follows:
Menthol ointment, is made up of the raw material of following weight portion:
Menthol 150-170 parts;
Camphor 90-110 parts;
Gaultherolin 90-110 parts;
Volatile oil extracted from eucalyptus' leaves or twigs 50-70 parts;
Attar of rose 90-110 parts;
Paraffin 170-190 parts;
Ceresine 2-4 parts;
Albolene 236-358 parts;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 110~120 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 55~65 DEG C, incorporation time is 45-50 minutes to temperature control, is finally filtered while hot, and 45~60 DEG C of holding is filling, i.e., .
Beneficial effects of the present invention:By reducing menthol, camphor usage amount, without thymol, suitable control bigcatkin willow The amount of sour methyl esters, increases Rosa Damascana, the amount of albolene gets a desired effect, and Rosa Damascana has good permeability, And good amalgamation, by directly exciting the items metabolism reaction of Skin Cell, active cell regeneration energy suppresses oxygen Free radical activity, strengthens CBF, and control Tyrosinase oxidation can decompose pigment as body help type beauty and skin care of new generation Product;Rosa Damascana is suitable as skin care maintenance, and with anti-ageing, wrinkle resistant and moisture-keeping efficacy, gaultherolin is rubefacient, can be promoted Local blood circulation, has anti-inflammatory analgetic to act on;Camphor, menthol are skin irritant, there is antipruritic, analgesic effect.
Specific embodiment
In order to deepen the understanding of the present invention, below in conjunction with embodiment, the invention will be further described, the embodiment It is only used for explaining the present invention, does not constitute the restriction to protection scope of the present invention.
Embodiment 1
Menthol ointment, is made up of the raw material of following weight portion:
150 parts of menthol;
90 parts of camphor;
90 parts of gaultherolin;
50 parts of volatile oil extracted from eucalyptus' leaves or twigs;
90 parts of attar of rose;
170 parts of paraffin;
2 parts of ceresine;
358 parts of albolene;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 110 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 55 DEG C, incorporation time is 45 minutes to temperature control, is finally filtered while hot, and 45 DEG C of holding is filling, obtains final product.
Embodiment 2
Menthol ointment, is made up of the raw material of following weight portion:
155 parts of menthol;
95 parts of camphor;
95 parts of gaultherolin;
55 parts of volatile oil extracted from eucalyptus' leaves or twigs;
95 parts of attar of rose;
175 parts of paraffin;
2.5 parts of ceresine;
327.5 parts of albolene;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 115 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 60 DEG C, incorporation time is 46 minutes to temperature control, is finally filtered while hot, and 47 DEG C of holding is filling, obtains final product.
Embodiment 3
Menthol ointment, is made up of the raw material of following weight portion:
160 parts of menthol;
100 parts of camphor;
100 parts of gaultherolin;
60 parts of volatile oil extracted from eucalyptus' leaves or twigs;
100 parts of attar of rose;
180 parts of paraffin;
2.5 parts of ceresine;
297.5 parts of albolene;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 115 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 60 DEG C, incorporation time is 47 minutes to temperature control, is finally filtered while hot, and 55 DEG C of holding is filling, obtains final product.
Embodiment 4
Menthol ointment, is made up of the raw material of following weight portion:
160 parts of menthol;
100 parts of camphor;
100 parts of gaultherolin;
60 parts of volatile oil extracted from eucalyptus' leaves or twigs;
100 parts of attar of rose;
180 parts of paraffin;
3 parts of ceresine;
297 parts of albolene;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 115 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 60 DEG C, incorporation time is 48 minutes to temperature control, is finally filtered while hot, and 55 DEG C of holding is filling, obtains final product.
Embodiment 5
Menthol ointment, is made up of the raw material of following weight portion:
165 parts of menthol;
105 parts of camphor;
105 parts of gaultherolin;
65 parts of volatile oil extracted from eucalyptus' leaves or twigs;
105 parts of attar of rose;
185 parts of paraffin;
3 parts of ceresine;
267 parts of albolene;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 115 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 60 DEG C, incorporation time is 48 minutes to temperature control, is finally filtered while hot, and 55 DEG C of holding is filling, obtains final product.
Embodiment 6
Menthol ointment, is made up of the raw material of following weight portion:
170 parts of menthol;
110 parts of camphor;
110 parts of gaultherolin;
70 parts of volatile oil extracted from eucalyptus' leaves or twigs;
110 parts of attar of rose;
190 parts of paraffin;
4 parts of ceresine;
236 parts of albolene;
It is total:1000 parts.
Menthol ointment preparation technology, comprises the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring Well mixed, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heats Temperature need to be controlled at 120 DEG C, stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not mistake Hurry up, at 65 DEG C, incorporation time is 50 minutes to temperature control, is finally filtered while hot, and 60 DEG C of holding is filling, obtains final product.
In order to overcome cooling ointment as seasonal product, it is adjusted by refrigerant oil formula, has both retained cooling ointment biography Outside the special efficacy of system, vaseline is used for reference again as the characteristic of skincare product, be fabricated to a kind of health treatment that can be used with the four seasons.
Menthol, camphor have promotion local circulation and slight anti-inflammatory, analgesic and itching-relieving action;Increase gaultherolin There can be the effect of sterilizing and itch-relieving;Addition attar of rose can prevent skin frostbite;By reducing the consumption of paraffin, increasing Bai Fanshi The amount of woods, can make product have the moist, function of skin care.
Without dragon's blood solution, the effect of dragon's blood is mainly toning and uses, is fabricated to for convenience cooling ointment in the present invention Brown cooling ointment.
Gaultherolin, attar of rose are used in the present invention, cooling ointment can be promoted to health-care and skin-care suitable for four seasons and used Product, both can it is refrigerant it is antipruritic, removal bite by mosquitos the effects such as, also with skin care, prevention winter skin frostbite function.
Gaultherolin is local external use's rubefacient.With local irritant effect, local blood circulation can be promoted, external application or Part embrocates the IR such as cutaneous vasodilation, the colour of skin can be produced rubescent, and reflectivity ground influence corresponding site skin, flesh Meat, nerve and joint, play detumescence, anti-inflammatory and analgesic activity, also there is antipruritic effect.For spraining, dampening, pain in the back, courbature, god It is dysmenorrhoea, antipruritic.
Rosa Damascana has antibacterial, anti-spasm, sterilization, purification, calmness, benefit body.It is applicable all skin quality especially ripe dry Dry or sensitivity, any sensitive red and swollen and inflammation skin.Rosa Damascana is the king of natural plant essential oils, and its natural fragrance is through smell god After entering human body, spiritual comfortable, pleasure, satisfied, alleviation anxiety, depression, pressure can be made one, helped for sleep, promote new old generation Thank, cytothesis, blood circulation, health, beauty can be made, life is finer.
1st, Rosa Damascana has good permeability, and good amalgamation.By directly exciting the items of Skin Cell new Old metabolic response, active cell regeneration energy, suppresses oxygen radical activity, strengthens CBF, control Tyrosinase oxidation;
2nd, pigment is decomposed, accelerates the balance of nutrient and moisture content, strengthen cytotoxic discharge, so as to reach to inside and outside skin The integrally-regulated and control of environment, as body help type cosmetics and skincare product of new generation;
3rd, Rosa Damascana is suitable as skin care maintenance, with anti-ageing, wrinkle resistant and moisture-keeping efficacy, it is adaptable to which various skin all have There is good curative effect.
Vaseline is a kind of mineral wax, and it will not be absorbed by the skin, and can form one diaphragm in skin surface, makes skin Moisture be difficult evaporation and scatter and disappear, and it is largely insoluble in water, can be attached on skin for a long time, therefore with good moisturizing effect Really, dry skin is very suitable for use.The great water proofing property of vaseline, is a kind of extraordinary moisturizing articles for use, for preparing medicine Ointment and skin sparing ointment raw material;The dispensing of cosmetic cream, face cream greasepaint etc..
Menthol ointment of the invention, the autumn, summer can as cooling ointment, essential wind oil have prevent bite by mosquitos, promoting blood circulationization The effect of stasis of blood;Winter, spring can have prevention frostbite and pachylosis, antipruritic, anticracking effect as kibe ointment.Not only The effect of can be used for bite by mosquitos and the skin care suitable for winter, prevent skin frostbite.

Claims (1)

1. a kind of menthol ointment preparation technology, it is characterised in that menthol ointment is made up of the raw material of following weight portion:
Menthol 150-170 parts;
Camphor 90-110 parts;
Gaultherolin 90-110 parts;
Volatile oil extracted from eucalyptus' leaves or twigs 50-70 parts;
Attar of rose 90-110 parts;
Paraffin 170-190 parts;
Ceresine 2-4 parts;
Albolene 236-358 parts;
It is total:1000 parts;
The menthol ointment is preparation technology comprise the following steps:
A, menthol, camphor are weighed, grind mixing, it is stand-by;
B, in dissolving tank, added after menthol, camphor dissolve each other main ingredient volatile oil extracted from eucalyptus' leaves or twigs, gaultherolin, attar of rose stirring mixing Uniformly, dissolution time is kept for more than 24 hours, winner's drug solns;
C and then albolene, paraffin, ceresine are sequentially added into heating in ma trix melting pot in order melts it, heating-up temperature Need to control at 110~120 DEG C, be stirred after after matrix melting;
D, first will main ingredient solution be pumped into mixing kettle in, open stirring, then control be pumped into matrix solution speed, should not be too fast, temperature At 55~65 DEG C, incorporation time is 45-50 minutes, is finally filtered while hot for degree control, and 45~60 DEG C of holding is filling, obtains final product.
CN201510071443.4A 2015-02-11 2015-02-11 A kind of menthol ointment and its preparation technology Active CN104666496B (en)

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Publication number Priority date Publication date Assignee Title
CN108451781A (en) * 2018-05-02 2018-08-28 华南农业大学 A kind of more curative effects apply ointment and preparation method thereof outside
CN110339230A (en) * 2019-07-11 2019-10-18 上海中华药业南通有限公司 A kind of faint scent menthol ointment and its manufacture craft
CN112386566A (en) * 2019-08-15 2021-02-23 天津金耀药业有限公司 Camphor ointment
CN113082118A (en) * 2021-04-14 2021-07-09 郭佳嵘 Tea oil mint paste and preparation method thereof
CN116898894A (en) * 2023-08-28 2023-10-20 张志华 External massage oil for skin and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101569701A (en) * 2009-06-09 2009-11-04 上海中华药业有限公司 Improved method for preparing 3.5g refined menthocamphorate
CN102366442A (en) * 2011-09-21 2012-03-07 吴江市顺昌日用品有限公司 Improved essential balm
CN104013544A (en) * 2014-05-27 2014-09-03 南通仟仟惠家化有限公司 Mosquito repellent mint paste
CN104147191A (en) * 2014-07-27 2014-11-19 青岛极致节能环保有限公司 Cooling ointment with refreshing effect

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101569701A (en) * 2009-06-09 2009-11-04 上海中华药业有限公司 Improved method for preparing 3.5g refined menthocamphorate
CN102366442A (en) * 2011-09-21 2012-03-07 吴江市顺昌日用品有限公司 Improved essential balm
CN104013544A (en) * 2014-05-27 2014-09-03 南通仟仟惠家化有限公司 Mosquito repellent mint paste
CN104147191A (en) * 2014-07-27 2014-11-19 青岛极致节能环保有限公司 Cooling ointment with refreshing effect

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
采用正交设计法优选清凉油基质配方;叶玉山等;《海峡药学》;19950430;第7卷(第4期);17-18 *

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