CN109432244A - A kind of Chinese medicine preparation and its preparation method and application improving sensitive skin state - Google Patents
A kind of Chinese medicine preparation and its preparation method and application improving sensitive skin state Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
The invention discloses a kind of Chinese medicine preparations and its preparation method and application for improving sensitive skin state, the formula is by weight, including following component: 1-4 parts of Honegsukle flower P.E, 1-4 parts of forsythia suspense extraction, 1-3 parts of silktree albizia bark extract, 1-3 parts of Cortex Dictamni extract, 1-2 parts of dried orange peel extracts, 1-2 parts of Salvia root P.E, 1-6 parts of Astragalus Root P.E, 1-4 parts of camomile extract, 1-4 parts of purslane extract, 1-4 parts of grape seed extract, 1-4 parts of loquat-leaf extract and 0.5-4 parts of licorice, the formula is during effective component extracting, the physiological function of Chinese medicine active material is kept to greatest extent, without using the production medium of toxic side effect, there is no secondary injury to human body, reliable performance safety, reach real day however comprehensive nursing efficacy, The formula is obtained effective component of chinese medicine, can be used as the adding ingredient of cosmetics or drug using the method extracted.
Description
Technical field
The present invention discloses the technical field for being related to Chinese medicine preparation more particularly to a kind of Chinese medicine for improving sensitive skin state is matched
Side and its preparation method and application.
Background technique
Great changes will take place for modern life environment, and empty gas and water, biology, daily life product can cause allergic problem.Cause
The original preservative of main sensitization (30%-40%), the spices and essence (20%-30%), surfactant (15% of berloque dermatitis
Left and right), in addition, sun-screening agent, antioxidant, antibacterial agent etc. can cause berloque dermatitis.Medically it is believed that skin is quick
Sense not instead of skin disease, dermoreaction height, poor resistance even easy allergy.In daily life, sensitive skin has no
Objective skin lesion or skin disease evidence, main performance be it is more dry, be easy tight and rubescent, by minimal irritation, can produce
Raw itch, furfur, or even burn and feel with shouting pain etc., serious person can produce unhealthy emotion or mental symptom.Due to sensitive skin
The complexity of the origin cause of formation and mechanism, the method that there is no specific treatment at present, thus targetedly use cosmetics and conscious day
Normal skin nursing is very important the susceptibility for alleviating skin.
Since sensitive skin often has barrier function damage or abnormality of nerve function, compared with normal skin more
It is difficult to resist the invasion of environmental stimuli object and anaphylactogen, is easy to happen a series of scytitis caused by stimulations or allergy and reacts,
Then skin barrier structure and nerve endings are further damaged, vicious circle is caused.Therefore maintenance and reparation skin barrier function are
Reduce the important means of skin sensitivity degree.
Therefore, a kind of pharmaceutical formulation that can have maintenance and repair to skin barrier function how is researched and developed, people are become
Urgent problem to be solved.
Summary of the invention
In consideration of it, the present disclosure provides a kind of Chinese medicine preparation for improving sensitive skin state and preparation method thereof and answering
With at least to solve the problems, such as that never having special efficacy for sensitive skin in the prior art releives method.
One aspect of the present invention provides a kind of Chinese medicine preparation for improving sensitive skin state, by weight, the Chinese medicine preparation
Including following component: 1-4 parts of Honegsukle flower P.E, 1-4 parts of forsythia suspense extraction, 1-3 parts of silktree albizia bark extract, Cortex Dictamni extract
1-3 parts, 1-2 parts of dried orange peel extracts, 1-4 parts of loquat-leaf extract, 1-6 parts of Astragalus Root P.E, 1-6 parts of Baical Skullcap root P.E, ocean it is sweet
1-4 parts of chrysanthemum extract, 1-4 parts of purslane extract, 1-4 parts of grape seed extract, 1-2 parts of Salvia root P.E and Radix Glycyrrhizae are extracted
0.5-4 parts of object.
It is preferred that the formula is liquid preparation for external use or externally used paste.
Another aspect of the present invention additionally provides a kind of method of Chinese medicine preparation for preparing above-mentioned improvement sensitive skin state, tool
Body includes the following steps:
1) extracting honeysuckle, Fructus Forsythiae, cortex albiziae, cortex dictamni, dried orange peel, loguat leaf, Radix Astragali, radix scutellariae, chamomile, dent in proportion
Amaranth, grape pip, Radix Salviae Miltiorrhizae and Radix Glycyrrhizae, it is spare；
2) above-mentioned spare medicinal material is put into after being impregnated 0.5-24 hours in the mixed liquor of water, alcohol or both together, is extracted
Effective component obtains extracting solution；Or above-mentioned spare medicinal material is respectively put into the mixed liquor of water, alcohol or both and impregnates 0.5-
After 24 hours, effective component extracting, the effective component of extraction is mixed respectively, obtains extracting solution；
3) the solid dregs of a decoction in extracting solution are filtered out, obtain liquid extract, sterile filling, or filter out the solid in extracting solution
After the dregs of a decoction, solvent evaporated obtains powdery or cream solid extract, sterile pack sealing.
It is preferred that the method for effective component extracting described in step 2) are as follows: solvent extraction, ultrasonic extraction and fermentation, extraction
One of or a variety of be used in combination.
Further preferably, the solvent extraction specifically: using water, alcohol or both mixed liquor as working media, described
Under the boiling temperature of working media, the medicinal material after immersion is flowed back 2-24 hours, obtains extracting solution.
Further preferably, the ultrasonic extraction specifically: using water, alcohol or both mixed liquor as working media, will soak
Twice, each extraction time is 40-60 minutes to medicinal material ultrasonic extraction after bubble, extracting solution will merge twice, and obtain final extract
Liquid.
Further preferably, the fermentation, extraction specifically: the medicinal material after immersion is put into fermentor, medicinal material weight is added
The leavening of 0-20% obtains extracting solution fermentation 7-15 days or more under the conditions of temperature is 12-39 DEG C.
Further preferably, the leavening is glucide, cellulase and/or probiotics.
In addition, the present invention also provides a kind of application of the Chinese medicine preparation of above-mentioned improvement sensitive skin state, the improvement
The Chinese medicine preparation of sensitive skin state is as cosmetics or the adding ingredient of drug.
It is preferred that the Chinese medicine preparation for improving sensitive skin state is cosmetics gross weight as the additive amount of cosmetic composition
The 10-50% of amount, prosthetic synthetic preservative, antibiotic, hormone.
It is mixed to extract natural component from various natural plants for the Chinese medicine preparation provided by the invention for improving sensitive skin state
It closes, chemical synthesis agent is much better than in terms of safety, after smearing on the skin, not only can form one layer of protection screen in skin surface
Barrier improves sensitivity, and to the irritation of sensitive skin also very low even zero.Specifically, in the formula, gold and silver
Flower, Fructus Forsythiae with the poison of removing summer-heat epidermis, cortex albiziae, cortex dictamni, dried orange peel can removing dampness through diuresis and relieving itching and with Pi Zhipi, and Radix Astragali, radix scutellariae
With more the raising immunity of modern pharmacological research, stimulation improves environment in skin, prevents the effect of aging, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae etc.
Promoting blood circulation disappears carbuncle, all medicine resultant forces make it is evil except eutopic reduction, wet go and dredge epidermis channels and collaterals.The Chinese medicine preparation of above-mentioned improvement sensitive skin state
For external prescription, using simple, conveniently, there are nursing very well, the effect of anti-inflammatory and antiallergic, the formula is by extracting in Chinese medicine
Effective component keeps the physiological function of Chinese medicine active material, without using the production medium of toxic side effect, to people to greatest extent
Body does not have secondary injury, and reliable performance safety reaches real day however comprehensive nursing efficacy.
The method that preparation provided by the invention improves the Chinese medicine preparation of sensitive skin state, it is main to be extracted by effective component
Mode, the effect of obtaining each taste Chinese medicine substance, by the way that effect material mixing is obtained the formula, which can be directly made into
External drug can also be used as the adding ingredient of external drug and improve the adding ingredient of sensitive skin state cosmetics.
It should be understood that above general description and following detailed description be only it is exemplary and explanatory, not
The disclosure can be limited.
Specific embodiment
The present invention is further explained with specific embodiment below, but be not intended to restrict the invention
Protection scope.
Currently, the effect method not improved for sensitive skin, in consideration of it, present embodiment provides a kind of improvement is quick
Feel the Chinese medicine preparation of skin condition, which mainly consists of the following compositions, 1-4 parts of honeysuckle, 1-4 parts of Fructus Forsythiae, cortex albiziae 1-3
Part, 1-3 parts of cortex dictamni, 1-2 parts of dried orange peel, 1-2 parts of Radix Salviae Miltiorrhizae, 1-6 parts of Radix Astragali, 1-4 parts of chamomile, 1-4 parts of purslane, grape pip 1-
4 parts, 1-4 parts of loguat leaf, 0.5-4 parts of Radix Glycyrrhizae.
Wherein, the dosage of above-mentioned each ingredient can according to the concrete condition of user (such as: age, skin quality, such as whether having dry
It is dry, tight, rubescent, the situations such as easy sunburn) it is determined, it is used with being suitable for different patients, one side of an example.
In above-mentioned Chinese medicine preparation, the concrete function effect of each ingredient is as follows:
1, honeysuckle: can dispelling wind-heat, also kind removing summer-heat blood poison is used for various febrile diseases, such as to dermexanthesis, macular eruption, heat toxin
The diseases such as sore carbuncle, equal significant effect.
2, Fructus Forsythiae: heat-clearing, removing toxic substances, dissipating bind, detumescence.
3, cortex albiziae: and blood, detumescence, analgesic.
4, cortex dictamni: heat-clearing and damp-drying drug, dispelling wind and arresting itching, removing toxic substances.
5, dried orange peel: fragrant odour, spread of pungent taste helps to keep warm are longer than qi-regulating, can ventilating.
6, loguat leaf: it is bitter, it is cool, enter lung, stomach meridian, to clearing stomach fire, lets out lung heat.
7, Astragalus Root P.E: invigorating qi for strengthening superficies, hidroschesis detoxification apocenosis, myogenic.
8, radix scutellariae: pharmacological property is cold and cool, there is heat-clearing and damp-drying drug, cool blood, detoxicating functions, cures mainly warm heat disease purging intense heat.
9, chamomile: the spirit that can calm, slow mood of relaxing, the skin for improving allergy.
10, purslane: clearing heat and promoting diuresis, removing toxicity for detumescence, anti-inflammatory analgetic.
11, grape pip: hypo-allergenic, free radical resisting, anti-radiation, protection skin.
12, Radix Salviae Miltiorrhizae: promoting blood circulation, relieving restlessness and restlessness, cool blood to disappear carbuncle.
13, Radix Glycyrrhizae: it is clearing heat and detoxicating, it is used for carbuncle sore tumefacting virus, anti-inflammatory, antibacterial, antiviral, promotion ulcer healing.
The Chinese medicine preparation of above-mentioned improvement sensitive skin state studies cosmetics contact dermatitis according to modern Western medicine and is divided into thorn
Swash property and allergy, wherein allergy is most common；It is that outer touching is color malicious and send out that Chinese medicine, which thinks mostly,.Filling out in cosmetics
Material, essence etc., because poor quality or be stained with it is stagnant lead to chosure of pores in epidermis, in addition exposing to the weather, make the heresy pent-up of color poison in skin
Skin, Yi Huare on fire floats on, or pain or itch.And the most skin pore of cosmetics type dermatitis patient is coarse, fat secretion is on the high side
Relatively meet the property of the damp evil of Chinese medicine.Therefore, the application Chinese medicine preparation selection has the effect of clearing heat, detoxicating, dispelling dampness, anti-inflammatory, antibacterial
Ingredient, realize improve sensitive skin state.Honeysuckle, Fructus Forsythiae are with the poison of removing summer-heat epidermis, and cortex albiziae, cortex dictamni, dried orange peel were both
Energy removing dampness through diuresis and relieving itching, and can be with Pi Zhipi, and modern pharmacological research shows the raising immunity that Radix Astragali, radix scutellariae have, stimulation improves
Environment in skin prevents the effect of aging；The promoting blood circulations such as Radix Salviae Miltiorrhizae, Radix Glycyrrhizae disappear carbuncle, and all medicine resultant forces make the evil dredging table except eutopic reduction wet go
Skin channels and collaterals.
The formula of the improvement sensitive skin state can be made into the exterior-applied formulations such as liquid preparation for external use or frost, cream, emulsion, extract
Effect ingredient in Chinese medicine keeps the physiological function of Chinese medicine active material, without using the life of toxic side effect to greatest extent
Medium is produced, prosthetic chemical preservative, antibiotic, hormone in formula avoid chemical addition agent from not having secondary injury, function to human body
It imitates reliable and secure, reaches real day however comprehensive nursing efficacy, improve skin to the state of extraneous environment sensitive.
Specific preparation process is as follows for above-mentioned improvement sensitive skin state formula:
1) extracting honeysuckle, Fructus Forsythiae, cortex albiziae, cortex dictamni, dried orange peel, loguat leaf, Radix Astragali, radix scutellariae, chamomile, dent in proportion
Amaranth, grape pip, Radix Salviae Miltiorrhizae and Radix Glycyrrhizae, it is spare；
2) spare medicinal material is put into after being impregnated 0.5-24 hours in the mixed liquor of water, alcohol or both together, is extracted effective
Ingredient obtains extracting solution；Or spare medicinal material is respectively put into the mixed liquor of water, alcohol or both and is impregnated 0.5-24 hours
Afterwards, difference effective component extracting, the effective component of extraction is mixed, and obtains extracting solution；
3) the solid dregs of a decoction in extracting solution are filtered out, obtain liquid extract, sterile filling, or filter out the solid in extracting solution
After the dregs of a decoction, solvent evaporated obtains powdered or cream solid extract, sterile pack sealing.
Wherein, each medicinal material is mixed in step 2) and impregnates latter same effective component extracting, or every kind of medicinal material is divided
Not Jin Pao after mixed after effective component extracting again, influence is had no on the essence of drug effect, can be selected according to the actual situation, and
The solvent usage for impregnating medicinal material is usually 0.5-20 times of medicinal material weight, is advisable with excessively inwhole medicinal materials.
For the extraction of medicinal material effective component in step 2), solvent extraction, ultrasonic extraction and fermentation extraction can be selected
It one or both of takes and three kinds is used in combination.
Solvent extraction specifically: using water, alcohol or both mixed liquor as working media, under the boiling temperature of working media
Medicinal material after immersion is flowed back 2-24 hours, obtains extracting solution by (usually room temperature is to 100 DEG C).
Ultrasonic extraction specifically: using water, alcohol or both mixed liquor as working media, the medicinal material ultrasound after immersion is mentioned
It takes twice, each extraction time is 40-60 minutes, extracting solution will merge twice, and obtain final extracting solution.
Fermentation, extraction specifically: the medicinal material after immersion is put into fermentor, the leavening of medicinal material weight 0-20% is added,
Fermentation 7-15 days or more under the conditions of temperature is 12-39 DEG C, extracting solution is obtained, wherein fermentation time, according to seasonal climate temperature
Degree, can suitably be adjusted, extend to 30-60 days；Leavening is glucide, cellulase and/or probiotics, wherein
Glucide is white sugar, rock sugar, brown sugar, honey or syrup.
The Chinese medicine preparation of the above-mentioned improvement sensitive skin state prepared, can be used as the addition of cosmetics or drug at
Point, wherein the additive amount as cosmetic composition is the 10-50% of cosmetics total weight, usual cosmetics are as follows: lotion, profit
Skin cream, creams, facial mask and face cleaning product etc. are free of artificial preservative, antibiotic, hormone, improve the sensitive shape of skin
State.
The present invention is further illustrated with specific embodiment below.
Embodiment 1
A kind of Chinese medicine preparation improving sensitive skin state, specific preparation process are as follows:
1) by weight, 1 part of extracting honeysuckle, 2 parts of Fructus Forsythiae, 1 part of cortex albiziae, 3 parts of cortex dictamni, 1 part of dried orange peel, loguat leaf 2
Part, 1 part of Radix Astragali, 1 part of radix scutellariae, 2 parts of chamomile, 3 parts of purslane, 1 part of grape pip, 2 parts of Radix Salviae Miltiorrhizae and 0.5 part of Radix Glycyrrhizae, it is spare；
2) above-mentioned spare medicinal material is put into after being impregnated 24 hours in 5 times of water together, is transferred in fermentor, Chinese medicine weight is added
1-2 parts of syrup ferment 15-20 days under the conditions of temperature is 12-39 DEG C, obtain extracting solution；
3) the solid dregs of a decoction in extracting solution are filtered out, sterile filling obtains liquid extract, is protected from light storage at the drying of cool place,
It is spare.
Embodiment 2
A kind of Chinese medicine preparation improving sensitive skin state, specific preparation process are as follows:
1) by weight, 4 parts of extracting honeysuckle, 1 part of Fructus Forsythiae, 3 parts of cortex albiziae, 2 parts of cortex dictamni, 1 part of dried orange peel, loguat leaf 1
Part, 4 parts of Radix Astragali, 6 parts of radix scutellariae, 1 part of chamomile, 4 parts of purslane, 4 parts of grape pip, 1 part of Radix Salviae Miltiorrhizae and 2 parts of Radix Glycyrrhizae, it is spare；
2) above-mentioned spare medicinal material is respectively put into after being impregnated 10 hours in 10 times of alcohol, it, will under the boiling temperature of alcohol
Medicinal material after immersion flows back 10 hours respectively, obtains each herbal extract；
3) after filtering out the solid dregs of a decoction in each herbal extract, each extracting solution is mixed, sterile filling, obtains liquid extraction
Object is protected from light storage at cool place is dry, spare.
Embodiment 3
A kind of Chinese medicine preparation improving sensitive skin state, specific preparation process are as follows:
1) by weight, 3 parts of extracting honeysuckle, 4 parts of Fructus Forsythiae, 2 parts of cortex albiziae, 1 part of cortex dictamni, 2 parts of dried orange peel, loguat leaf 4
Part, 6 parts of Radix Astragali, 4 parts of radix scutellariae, 4 parts of chamomile, 1 part of purslane, 2 parts of grape pip, 1 part of Radix Salviae Miltiorrhizae and 4 parts of Radix Glycyrrhizae, it is spare；
2) above-mentioned spare medicinal material is put into together after being impregnated 20 hours in 5 times of water and alcohol blend, by the medicine after immersion
Twice, each extraction time is 40-60 minutes to material ultrasonic extraction, extracting solution will merge twice, and obtain final extracting solution；
3) the solid dregs of a decoction in extracting solution are filtered out, sterile filling obtains liquid extract, is protected from light storage at the drying of cool place,
It is spare.
Embodiment 4
Liquid extract will be prepared in embodiment 1-3, respectively according to toner is made as following formula, by weight,
1 part of extracting solution, 1 part of glycerol, 5 parts of distilled water.
Choose 9 sensitive skin persons, wherein 3 patients daily morning and evening 2 times with using extracting solution configuration in embodiment 1
Toner is nursed, and 3 patients are nursed for the morning and evening 2 times daily with the toner using extracting solution configuration in embodiment 2, and 4
Example patient is nursed for 2 times daily with the toner using extracting solution configuration in embodiment 3 sooner or later, during which avoid eating animal tallow and
The irritable foods such as wine, peppery, sweet tea, specific time result see the table below.
Experimental result
Remarks: above scoring mark are as follows: score according to dry, tight, rubescent, fash and severity, just
It is often 0 point, slight is 2 points, and moderate is 4 points, and severe is 6 points, and score is higher, and expression degree of allergic reaction is higher.
Typical case 1, female 57 years old, berloque dermatitis was seen a doctor 2 weeks in vain, using after this toner, is restored after a week.
Typical case 2, female 22 years old, there was acne shape rash at facial back, and the several months, it is invalid to see a doctor, and sprayed this toner, after two weeks,
Symptom disappears.
Embodiment 5
With the extracting solution in suitable embodiment 1-3, the materials such as silk, non-woven fabrics, poly- fruit acyl are sufficiently infiltrated, according to skin
Situation can add olive oil, natural VE in right amount, with can be made into facial mask finished product after aluminium foil bag aseptic packaging, have improvement skin quick
Perception, moisturizing, whitening function.
Embodiment 6
Newborn wooden 1 part of the fruit is taken, 13 parts of Sweet Almond Oil, 3 parts of emulsifying wax, 1 part of vitamin E, is added in reaction kettle, is constantly stirring
It mixes down and is heated to 70-75 degree, be added synthermal distilled water 60-80 parts, continue stirring 10-15 minutes.1 part of xanthan gum of addition, then
Stirring 10-15 minutes.Being cooled to temperature of reaction kettle is 40 degree, and the extracting solution of 20-40 parts of embodiment 1-3 preparation is added, and stirs 10-
15 minutes, aseptic canning sealing, dry shady place was protected from light storage, can be applied to acne affected part and do milky lotion use.
Those skilled in the art after considering the specification and implementing the invention disclosed here, will readily occur to of the invention its
Its embodiment.This application is intended to cover any variations, uses, or adaptations of the invention, these modifications, purposes or
Person's adaptive change follows general principle of the invention and including the undocumented common knowledge in the art of the present invention
Or conventional techniques.The description and examples are only to be considered as illustrative, and true scope and spirit of the invention are wanted by right
It asks and points out.
It should be understood that the invention is not limited to the content being described above, can without departing from the scope into
Row various modifications and change.The scope of the present invention is limited only by the attached claims.
Claims (10)
1. a kind of Chinese medicine preparation for improving sensitive skin state, which is characterized in that by weight, including following component: honeysuckle
1-4 parts of extract, 1-4 parts of forsythia suspense extraction, 1-3 parts of silktree albizia bark extract, 1-3 parts of Cortex Dictamni extract, dried orange peel extracts 1-2
Part, 1-4 parts of loquat-leaf extract, 1-6 parts of Astragalus Root P.E, 1-6 parts of Baical Skullcap root P.E, 1-4 parts of camomile extract, purslane
1-4 parts of extract, 1-4 parts of grape seed extract, 1-2 parts of Salvia root P.E and 0.5-4 parts of licorice.
2. improving the Chinese medicine preparation of sensitive skin state according to claim 1, which is characterized in that the formula is external use liquid
Body medicament or externally used paste.
3. a kind of prepare the method for improving the Chinese medicine preparation of sensitive skin state described in claim 1, which is characterized in that including such as
Lower step:
1) in proportion extracting honeysuckle, Fructus Forsythiae, cortex albiziae, cortex dictamni, dried orange peel, Radix Salviae Miltiorrhizae, Radix Astragali, chamomile, purslane, grape pip,
Loguat leaf and Radix Glycyrrhizae, it is spare；
2) above-mentioned spare medicinal material is put into after being impregnated 0.5-24 hours in the mixed liquor of water, alcohol or both together, is extracted effective
Ingredient obtains extracting solution；Or above-mentioned spare medicinal material is respectively put into the mixed liquor of water, alcohol or both to impregnate 0.5-24 small
Shi Hou, effective component extracting, the effective component of extraction is mixed respectively, obtains extracting solution；
3) the solid dregs of a decoction in extracting solution are filtered out, obtain liquid extract, sterile filling, or filter out the solid dregs of a decoction in extracting solution
Afterwards, solvent evaporated obtains powdery or cream solid extract, sterile pack sealing.
4. preparing the method for improving the Chinese medicine preparation of sensitive skin state according to claim 3, which is characterized in that step 2)
Described in effective component extracting method are as follows: one of solvent extraction, ultrasonic extraction and fermentation, extraction or a variety of joints
It uses.
5. preparing the method for improving the Chinese medicine preparation of sensitive skin state according to claim 4, which is characterized in that described molten
Agent extraction specifically: using water, alcohol or both mixed liquor as working media, under the boiling temperature of the working media, will soak
Medicinal material after bubble flows back 2-24 hours, obtains extracting solution.
6. preparing the method for improving the Chinese medicine preparation of sensitive skin state according to claim 4, which is characterized in that described super
Sound wave extraction specifically: using water, alcohol or both mixed liquor as working media, twice by the medicinal material ultrasonic extraction after immersion, often
Secondary extraction time is 40-60 minutes, extracting solution will merge twice, and obtain final extracting solution.
7. preparing the method for improving the Chinese medicine preparation of sensitive skin state according to claim 4, which is characterized in that the hair
Ferment extraction specifically: the medicinal material after immersion is put into fermentor, the leavening of medicinal material weight 0-20% is added, is in temperature
It ferments 7-15 days or more under the conditions of 12-39 DEG C, obtains extracting solution.
8. preparing the method for improving the Chinese medicine preparation of sensitive skin state according to claim 7, which is characterized in that the hair
Ferment agent is glucide, cellulase and/or probiotics.
9. improving the application of the Chinese medicine preparation of sensitive skin state described in a kind of claim 1, which is characterized in that the improvement is quick
The Chinese medicine preparation of skin condition is felt as cosmetics or the adding ingredient of drug.
10. improving the application of the Chinese medicine preparation of sensitive skin state according to claim 9, which is characterized in that the improvement
The Chinese medicine preparation of sensitive skin state as cosmetic composition additive amount be cosmetics total weight 10-50%.
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Cited By (1)
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