CN107412366A - Chinese medicine composition antibacterial for skin pruritus and preparation method thereof - Google Patents
Chinese medicine composition antibacterial for skin pruritus and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition antibacterial for skin pruritus, the Chinese medicine composition is made up of following material：The 100g of kuh-seng 80, the 100g of sulphur 85, the 30g of cow-bezoar 20, the 50g of the coptis 30, the 100g of frutus cnidii 80, the 20g of antelope's horn 10, the 100g of cloves 85, the 50g of moutan bark 25, the 10g of menthol 5, the 20g of borneol 10, the 100g of beeswax 70, the 1500ml of sesame oil 1200；Also disclose a kind of preparation method for the antibacterial Chinese medicine composition of skin pruritus, the present invention has the function of sterilizing and suppress fungi, treat it is dermopathic during have desinsection, sterilization, heat-clearing and damp-drying drug, wind-dispelling heat-dissipating, detoxify, the carbuncle that disappears, the function such as antipruritic.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine composition antibacterial for skin pruritus.
Background technology
Itch is the common disease of dept. of dermatology, is mainly shown as only pruitus without primary skin lesion, treats relative difficulty, easily recurrence.Itch is one of main subjective symptoms of multiple dermatosis, and pruritus dermatopathy mainly includes cutaneous pruritus, neurodermatitis, papular urticaria, chronic eczema, tinea of feet and hands, scabies, prurigo nodularis and summer dermatitis etc..Because the pruritus dermatopathy cause of disease is complicated, inducement is more, is dept. of dermatology's common clinical, frequently-occurring disease, accounts for more than the 80% of Dermatology Outpatient Department patient, brings considerable distress to patient, quality of life is decreased obviously.
China's most area is because of the multiple skin disease of climate reasons, also aggravates easily original skin disease.Under high hot weather, wind-heat, sweat drainage difficulty and summer another common disease-eczema etc. cause pruitus, and due to itch, scratching easily causes the infection of staphylococcus, streptococcus and fungi, and pruitus aggravates, causes and fester.Much more clinical mainly apply antibiotic and hormone using for oral administration and external application, at present pruitus treatment, side effect is very big, there is certain effect in short term, once deactivation will recurrent exerbation, have certain dependence.
The content of the invention
In view of this, it is a primary object of the present invention to provide a kind of Chinese medicine composition antibacterial for skin pruritus and preparation method thereof.
To reach above-mentioned purpose, the technical proposal of the invention is realized in this way：
The embodiment of the present invention provides a kind of Chinese medicine composition antibacterial for skin pruritus, and the Chinese medicine composition is made up of following material：Kuh-seng 80-100g, sulphur 85-100g, cow-bezoar 20-30g, coptis 30-50g, frutus cnidii 80-100g, antelope's horn 10-20g, cloves 85-100g, moutan bark 25-50g, menthol 5-10g, borneol 10-20g, beeswax 70-100g, sesame oil 1200-1500ml.
In such scheme, the formulation of the Chinese medicine composition is paste.
In such scheme, the Chinese medicine composition is also made up of following auxiliary material：Glycerine 120-150g, vaseline 160-200g, ethylparaben 2.0-2.5g, atoleine 45-60g, Tween-80 3-5g, acetic acid chlorhexidine 2.5-3g, lanolin 160-180g, purified water 150-300ml.
The embodiment of the present invention also provides a kind of preparation method of the Chinese medicine composition antibacterial for skin pruritus, and the preparation method is realized by following steps：
Step 1：By after medicinal material net system, it is standby；
Step 2：It is fine powder by 85-100g sulphur, 5-10g menthols, 10-20g borneol and grindings, it is standby；
Step 3：80-100g kuh-sengs, 20-30g cow-bezoars, the 30-50g coptiss, 80-100g frutus cnidiis, 10-20g antelope's horns, 85-100g cloves, 25-50g moutan barks are ground into after coarse powder after adding the immersion of 1200-1500ml sesame oil 7 days; filtered after being cooked by slow fire 2 hours, 70-100g beeswaxs are added in filtrate and stirred;
Step 4：Fine powder made from adding step 2 when whipping temp is down to 40-50 DEG C stirs, and it is standby that medicinal extract is made；
Step 5：Take 2.5-3g acetic acid chlorhexidine, 2.0-2.5g ethylparabens, 3-5g Tween-80s add 150-300mlization water be heated to 70-80 DEG C mixing, stir, with step 4 made from medicinal extract mix it is standby；
Step 6：160-200g vaseline, 120-150g glycerine, 120-150g atoleines, 160-180g lanolin is taken to be heated to 70-80 DEG C, fusing mixes with medicinal extract made from step 5, is sufficiently stirred until cooling；
Step 7：15g/ branch is dispensed, is examined, is packed, is sterilized, storage.
Compared with prior art, beneficial effects of the present invention：
The present invention has the function of sterilizing and suppress fungi, treat it is dermopathic during have desinsection, sterilization, heat-clearing and damp-drying drug, wind-dispelling heat-dissipating, detoxify, the carbuncle that disappears, the function such as antipruritic.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, the present invention will be described in further detail.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not intended to limit the present invention.
The embodiment of the present invention provides a kind of Chinese medicine composition antibacterial for skin pruritus, and the Chinese medicine composition is made up of following material：Kuh-seng 80-100g, sulphur 85-100g, cow-bezoar 20-30g, coptis 30-50g, frutus cnidii 80-100g, antelope's horn 10-20g, cloves 85-100g, moutan bark 25-50g, menthol 5-10g, borneol 10-20g, beeswax 70-100g, sesame oil 1200-1500ml.
The formulation of the Chinese medicine composition is paste.
The Chinese medicine composition is also made up of following auxiliary material：Glycerine 120-150g, vaseline 160-200g, ethylparaben 2.0-2.5g, atoleine 45-60g, Tween-80 3-5g, acetic acid chlorhexidine 2.5-3g, lanolin 160-180g, purified water 150-300ml.
The embodiment of the present invention provides a kind of preparation method of the Chinese medicine composition antibacterial for skin pruritus, and the preparation method is realized by following steps：
Step 1：By after medicinal material net system, it is standby；
Step 2：It is fine powder by 85-100g sulphur, 5-10g menthols, 10-20g borneol and grindings, it is standby；
Step 3：80-100g kuh-sengs, 20-30g cow-bezoars, the 30-50g coptiss, 80-100g frutus cnidiis, 10-20g antelope's horns, 85-100g cloves, 25-50g moutan barks are ground into after coarse powder after adding the immersion of 1200-1500ml sesame oil 7 days; filtered after being cooked by slow fire 2 hours, 70-100g beeswaxs are added in filtrate and stirred;
Step 4：Fine powder made from adding step 2 when whipping temp is down to 40-50 DEG C stirs, and it is standby that medicinal extract is made；
Step 5：Take 2.5-3g acetic acid chlorhexidine, 2.0-2.5g ethylparabens, 3-5g Tween-80s add 150-300ml purified waters be heated to 70-80 DEG C mixing, stir, with step 4 made from medicinal extract mix it is standby；
Step 6：160-200g vaseline, 120-150g glycerine, 120-150g atoleines, 160-180g lanolin is taken to be heated to 70-80 DEG C, fusing mixes with medicinal extract made from step 5, is sufficiently stirred until cooling；
Step 7：15g/ branch is dispensed, is examined, is packed, is sterilized, storage.
Embodiment 1：
The embodiment of the present invention 1 provides a kind of Chinese medicine composition antibacterial for skin pruritus, and the Chinese medicine composition is made up of following material：Kuh-seng 80g, sulphur 85g, cow-bezoar 20g, coptis 30g, frutus cnidii 80g, antelope's horn 10g, cloves 85g, moutan bark 25g, menthol 5g, borneol 10g, beeswax 70g, sesame oil 1200ml.
The formulation of the Chinese medicine composition is paste.
The Chinese medicine composition is also made up of following auxiliary material：Glycerine 120g, vaseline 160g, ethylparaben 2.0g, atoleine 45g, Tween-80 3g, acetic acid chlorhexidine 2.5g, lanolin 160g, purified water 150ml.
Realized by following steps：
Step 1：By after medicinal material net system, it is standby；
Step 2：It is fine powder by 85g sulphur, 5g menthols, 10g borneol and grindings, it is standby；
Step 3：80g kuh-sengs, 20g cow-bezoars, the 30g coptiss, 80g frutus cnidiis, 10g antelope's horns, 85-100g cloves, 25g moutan barks are ground into after coarse powder after adding the immersion of 1200ml sesame oil 7 days, are filtered after being cooked by slow fire 2 hours, 70g beeswaxs are added in filtrate and stirred;
Step 4：Fine powder made from adding step 2 when whipping temp is down to 40 DEG C stirs, and it is standby that medicinal extract is made；
Step 5：Take 2.5g acetic acid chlorhexidine, 2.0g ethylparabens, 3g Tween-80s add 150ml purified waters be heated to 70 DEG C mixing, stir, with step 4 made from medicinal extract mix it is standby；
Step 6：160g vaseline, 120g glycerine, 120g atoleines, 160g lanolin is taken to be heated to 70 DEG C, fusing mixes with medicinal extract made from step 5, is sufficiently stirred until cooling；
Step 7：15g/ branch is dispensed, is examined, is packed, is sterilized, storage.
Embodiment 2：
The embodiment of the present invention 2 provides a kind of Chinese medicine composition antibacterial for skin pruritus, and the Chinese medicine composition is made up of following material：Kuh-seng 90g, sulphur 92.5g, cow-bezoar 25g, coptis 40g, frutus cnidii 90g, antelope's horn 15g, cloves 92.5g, moutan bark 37.5g, menthol 7.5g, borneol 15g, beeswax 85g, sesame oil 1350ml.
The formulation of the Chinese medicine composition is paste.
The Chinese medicine composition is also made up of following auxiliary material：Glycerine 135g, vaseline 180g, ethylparaben 2.25g, atoleine 52.5g, Tween-80 4g, acetic acid chlorhexidine 2.75g, lanolin 170g, purified water 225ml.
Realized by following steps：
Step 1：By after medicinal material net system, it is standby；
Step 2：It is fine powder by 92.5g sulphur, 7.5g menthols, 15g borneol and grindings, it is standby；
Step 3：90g kuh-sengs, 25g cow-bezoars, the 40g coptiss, 90g frutus cnidiis, 15g antelope's horns, 92.5g cloves, 37.5g moutan barks are ground into after coarse powder after adding the immersion of 1400ml sesame oil 7 days, are filtered after being cooked by slow fire 2 hours, 85g beeswaxs are added in filtrate and stirred;
Step 4：Fine powder made from adding step 2 when whipping temp is down to 45 DEG C stirs, and it is standby that medicinal extract is made；
Step 5：Take 2.75g acetic acid chlorhexidine, 2.25g ethylparabens, 4g Tween-80s add 225ml purified waters be heated to 75 DEG C mixing, stir, with step 4 made from medicinal extract mix it is standby；
Step 6：180g vaseline, 135g glycerine, 1350g atoleines, 170g lanolin is taken to be heated to 75 DEG C, fusing mixes with medicinal extract made from step 5, is sufficiently stirred until cooling；
Step 7：15g/ branch is dispensed, is examined, is packed, is sterilized, storage.
Embodiment 3：
The embodiment of the present invention 3 provides a kind of Chinese medicine composition antibacterial for skin pruritus, and the Chinese medicine composition is made up of following material：Kuh-seng 100g, sulphur 100g, cow-bezoar 30g, coptis 50g, frutus cnidii 100g, antelope's horn 20g, cloves 100g, moutan bark 50g, menthol 10g, borneol 20g, beeswax 100g, sesame oil 1500ml.
The formulation of the Chinese medicine composition is paste.
The Chinese medicine composition is also made up of following auxiliary material：Glycerine 150g, vaseline 200g, ethylparaben 2.5g, atoleine 60g, Tween-80 5g, acetic acid chlorhexidine 3g, lanolin 180g, purified water 300ml.
Realized by following steps：
Step 1：By after medicinal material net system, it is standby；
Step 2：It is fine powder by 100g sulphur, 10g menthols, 20g borneol and grindings, it is standby；
Step 3：100g kuh-sengs, 30g cow-bezoars, the 50g coptiss, 100g frutus cnidiis, 20g antelope's horns, 100g cloves, 50g moutan barks are ground into after coarse powder after adding the immersion of 1500ml sesame oil 7 days, are filtered after being cooked by slow fire 2 hours, 100g beeswaxs are added in filtrate and stirred;
Step 4：Fine powder made from adding step 2 when whipping temp is down to 50 DEG C stirs, and it is standby that medicinal extract is made；
Step 5：Take 3g acetic acid chlorhexidine, 2.5g ethylparabens, 5g Tween-80s add 300ml purified waters be heated to 80 DEG C mixing, stir, with step 4 made from medicinal extract mix it is standby；
Step 6：200g vaseline, 150g glycerine, 150g atoleines, 180g lanolin is taken to be heated to 80 DEG C, fusing mixes with medicinal extract made from step 5, is sufficiently stirred until cooling；
Step 7：15g/ branch is dispensed, is examined, is packed, is sterilized, storage.
Kuh-seng：With heat-clearing and damp-drying drug, desinsection, diuresis function,《Surgery card controls pandect》Described in control mange.Modern study proves：Kuh-seng contains a variety of alkaloids, such as matrine, oxymatrine, Iosmatrine, sophocarpine, and its decoction has obvious inhibitory action to tubercle bacillus, golden yellow grape bacillus and a variety of dermatophytes.
Frutus cnidii：《Dictionary of medicinal plant》In recorded eliminating dampness wind-dispelling, desinsection it is antipruritic, for eczema itch.Honeysuckle exists《Dictionary of medicinal plant》In recorded clearing heat and detoxicating, dispelling wind and heat from the body.
Antelope's horn：《Pharmacopoeia of People's Republic of China》In recorded the removing toxic substances of scattered blood, for febrile virulent maculae, carbuncle sore tumefacting virus.
Cow-bezoar：《Compendium of Materia Medica》In recorded clearing heat and detoxicating, cure mainly abscess of throat, aphthae, ulcer serious case of furuncle.
The effect of borneol is inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain.Acetic acid chlorhexidine is cationic surfactant, has a broad antifungal spectrum, has killing action to most Grain-positives and negative bacteria, also effective to Pseudomonas aeruginosa.
Sulphur：《People's Republic of China's dictionary》Described in external application removing toxic substances, desinsection treat sore, for Jie tinea, the favus of the scalp, cloudy subcutaneous ulcer malignant sore.
Cloves：《Mingyi Bielu》Described in treat geomantic omen poison swollen, remove bad odor, it is pained to treat cholera.
The coptis：《Dictionary of medicinal plant》In recorded removing toxic substances, desinsection, row heat toxin when controlling, typhoid fever, for skin sore, eczema, the burning hot wound of soup.《Pharmacopoeia of People's Republic of China》In recorded heat-clearing and damp-drying drug, control eczema, wet sore outside, duct is suppurated, carbuncle swells furunculosis.《Sheng Nong's herbal classic》Described in main hot gas, mesh pain, weep, improving eyesight, treat aphtha.
Moutan bark：《Sheng Nong's herbal classic》Described in main fever and chills, five viscera settling, treat ulcerative carbuncle.
Menthol：Modern medicine is used for pruitus and pruritus dermatopathy caused by a variety of causes outside proving.
Beeswax：《Medical center collection will》Described in control burn sore, red pain, poison is rotten into purulence, and pulling out heat toxin with this relieves the pain pain sore mouth.
Sesame oil：《A thousand pieces of gold food therapys》Described in apply all malignant sore mange, kill all worms.
The formula composition medicine of the present invention is respectively provided with sterilization and suppresses the function of fungi, treat it is dermopathic during have desinsection, sterilization, heat-clearing and damp-drying drug, wind-dispelling heat-dissipating, detoxify, the carbuncle that disappears, the function such as antipruritic, have the foundation of science.
Case data：
Following patients are treated using Chinese medicine composition made from embodiment 2, concrete condition is as follows：
1st, Mr. Li, male, 76 years old, flat protuberance hemispherical or the hard itch of polygonal papule, quality play unbearably in shoulder first portion in 1993, four limbs large area, and hospital diagnosis is skin amyloidosis, and external application uses Chinese medicine composition made from embodiment 2, three courses for the treatment of are cured, and long-term pay a return visit is not recurred.
2nd, patient Bai, man, 64 years old, suffers from solar dermatitis eczema in 2012, exposure portion is very itched hard to bear, and whole face festers flowing water, can not fall asleep all night, is treated in multiple hospitals, diagnosis and treatment curative effect is not good enough, uses Chinese medicine composition made from embodiment 2 through external application, 3 take effect；Adhere to using and use Chinese medicine composition made from embodiment 2 to fully recover January, follow-up 2 years, so far without recurrence.
3rd, Huang, man, 62 years old, senile pruritus is suffered from, external application uses Chinese medicine composition made from embodiment 2, cures January, return visit is not recurred so far.
4th, Lee, female, 30 years old, eye circumference enclosed rubescent, medical history of itching 1 year, and external application is taken effect for one week using Chinese medicine composition made from embodiment 2, and January cures, and pays a return visit no recurrence.
The foregoing is only a preferred embodiment of the present invention, is not intended to limit the scope of the present invention.
Claims (4)
1. a kind of Chinese medicine composition antibacterial for skin pruritus, it is characterised in that the Chinese medicine composition is made up of following material：Kuh-seng 80-100g, sulphur 85-100g, cow-bezoar 20-30g, coptis 30-50g, frutus cnidii 80-100g, antelope's horn 10-20g, cloves 85-100g, moutan bark 25-50g, menthol 5-10g, borneol 10-20g, beeswax 70-100g, sesame oil 1200-1500ml.
2. the Chinese medicine composition antibacterial for skin pruritus according to claim 1, it is characterised in that：The formulation of the Chinese medicine composition is paste.
3. the Chinese medicine composition antibacterial for skin pruritus according to claim 2, it is characterised in that：The Chinese medicine composition is also made up of following auxiliary material：Glycerine 120-150g, vaseline 160-200g, ethylparaben 2.0-2.5g, atoleine 45-60g, Tween-80 3-5g, acetic acid chlorhexidine 2.5-3g, lanolin 160-180g, purified water 150-300ml.
4. a kind of preparation method of the Chinese medicine composition antibacterial for skin pruritus, it is characterised in that the preparation method is realized by following steps：
Step 1：By after medicinal material net system, it is standby；
Step 2：It is fine powder by 85-100g sulphur, 5-10g menthols, 10-20g borneol and grindings, it is standby；
Step 3：80-100g kuh-sengs, 20-30g cow-bezoars, the 30-50g coptiss, 80-100g frutus cnidiis, 10-20g antelope's horns, 85-100g cloves, 25-50g moutan barks are ground into after coarse powder after adding the immersion of 1200-1500ml sesame oil 7 days; filtered after being cooked by slow fire 2 hours, 70-100g beeswaxs are added in filtrate and stirred;
Step 4：Fine powder made from adding step 2 when whipping temp is down to 40-50 DEG C stirs, and it is standby that medicinal extract is made；
Step 5：Take 2.5-3g acetic acid chlorhexidine, 2.0-2.5g ethylparabens, 3-5g Tween-80s add 150-300ml purified waters be heated to 70-80 DEG C mixing, stir, with step 4 made from medicinal extract mix it is standby；
Step 6：160-200g vaseline, 120-150g glycerine, 120-150g atoleines, 160-180g lanolin is taken to be heated to 70-80 DEG C, fusing mixes with medicinal extract made from step 5, is sufficiently stirred until cooling；
Step 7：15g/ branch is dispensed, is examined, is packed, is sterilized, storage.
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| CN201610324913.8A CN107412366A (en) | 2016-05-17 | 2016-05-17 | Chinese medicine composition antibacterial for skin pruritus and preparation method thereof |
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| CN201610324913.8A CN107412366A (en) | 2016-05-17 | 2016-05-17 | Chinese medicine composition antibacterial for skin pruritus and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186882A (en) * | 2018-02-01 | 2018-06-22 | 重庆跃龙生物制药有限公司 | Skin bacteriostatic Chinese medicinal composition and preparation method thereof |
| CN111840314A (en) * | 2020-07-14 | 2020-10-30 | 徐大伟 | Eczema ointment and preparation method thereof |
| CN115887526A (en) * | 2022-11-04 | 2023-04-04 | 中山大学附属第六医院 | External preparation for treating anal pruritus and preparation method thereof |
-
2016
- 2016-05-17 CN CN201610324913.8A patent/CN107412366A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186882A (en) * | 2018-02-01 | 2018-06-22 | 重庆跃龙生物制药有限公司 | Skin bacteriostatic Chinese medicinal composition and preparation method thereof |
| CN111840314A (en) * | 2020-07-14 | 2020-10-30 | 徐大伟 | Eczema ointment and preparation method thereof |
| CN115887526A (en) * | 2022-11-04 | 2023-04-04 | 中山大学附属第六医院 | External preparation for treating anal pruritus and preparation method thereof |
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Application publication date: 20171201 |