CN106692334A - Pain relieving traditional Chinese medicine composition as well as preparation method and application thereof - Google Patents
Pain relieving traditional Chinese medicine composition as well as preparation method and application thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention relates to the technical field of traditional Chinese medicine preparations and particularly relates to a pain relieving traditional Chinese medicine composition as well as preparation method and application thereof. The pain relieving traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3.5-10.5 parts of aristolochia fordiana, 3-9 parts of ficus pumila, 3-9 parts of gecko, 3-9 parts of herb of laciniate blumea, 3-9 parts of schizophragma integrifolium, 3-9 parts of safflower, 3-9 parts of frankincense, 3-9 parts of myrrh, 3-9 parts of radix dipsaci, 3-9 parts of native copper, 3-9 parts of lamiophlomis rotate, 2.5-7.5 parts of paniculate swallowwort root, 2.5-7.5 parts of radix clematidis, 2-6 parts of notopterygium incisum, 2-6 parts of radix angelicae pubescentis, 2-6 parts of angelica sinensis, 2-6 parts of pine nodular branch, 1-3 parts of radix angelicae, 1-3 parts of borneol and 0.5-1.5 parts of menthol. The composition provided by the invention is applied to the drugs for various pain caused by wind-cold-dampness arthralgia and bruise stasis swelling as well as carbuncle swelling, dizziness, obnubilation and snake-insect bite; the invention also provides a preparation method of the traditional Chinese medicine composition.
Description
【Technical field】
The present invention relates to technical field of traditional Chinese medicine preparation, and in particular to a kind of Traditional Chinese medicine used as analgesic composition and preparation method thereof and should
With.
【Background technology】
Card is at first reaction of the various diseases in human body, such as cardio-cerebral diseases, vascular diseases, disease in the liver and gallbladder, wound, god
Through systemic disease, tumour etc., it may be said that be bitterly a kind of most common biological phenomena.Why we may feel that painIn
Doctor often says " General rules do not hurt, pain is not unreasonable ".Normally operation is fluent to whole body along respective channels and collaterals sering for qi and blood essence body fluid,
The foster vital organs of the human body are moistened, makes one to feel energetic, it is energetic, it is not felt by pain.And if these small pipelines of channels and collaterals are a certain
Place is stifled by the stasis of blood, and stagnation of QI-blood, it is impossible to circulate influences whether the normal operation of whole machine at once.Once the stasis of blood is blocked up, it is impossible to dredged in time
Logical, in the course of time, qi depression to blood stasis is formed accumulates poison in vivo, will make one to produce pain.《Plain Questions is lifted pain and is discussed》Say：" channels and collaterals stream
Row is more than, and ring week, cold air entered through then checking late endlessly, tears and it is not all right, visitor in then blood is few outside arteries and veins, visitor's then flow of QI being obstructed in arteries and veins, therefore soldier
But pain.”
Wind-cold-dampness arthralgia, Chinese medical disease name is the gas exopathogen of wind, cold, wet three invasion and attack channels and collaterals, and qi and blood impatency does not cause freely, is
Row (wind) numbness, pain (cold) numbness, work (wet) numbness are collectively referred to as, and are common to cause one of cause of disease of pain.Because wet three gas of chill is miscellaneous extremely, cause
Stagnation of QI-blood, card is shown in body weight and pain, spasm of limbs, very then walks to note pain, or numb in every limb etc..It is exopathogen invasion and attack channels and collaterals, qi and blood
Impatency is not smooth, causes joint, limbs etc. the symptoms, entitled bi Zheng such as acid, pain, fiber crops, weight and joint stuffiness occur.Wind, cold, wet disease
Heresy stays note muscle, muscles and bones, joint, causes channels and collaterals to be jammed, and QI-blood circulation is not smooth, and limbs spasm of muscles and vessels, mistake support basic for this disease
The interpretation of the cause, onset and process of an illness.But chill diseases caused by dampness is evil to emphasize particularly on different fields to suffer from, and ailment said due to cold or exposure notably, flee by disease and evil, and lesion migration is indefinite；Cold-evil notably, stern sun
Gas, sharp ache；Damp evil notably, sticks together solidification, and lesion calmness is not moved.With the passing of time numbness disease does not heal, and qi-blood-body fluid runs not smooth disease
Become day very, blood-vessel obstructive, body fluid cohesion, phlegm and blood stasis, impatency channels and collaterals go deep into bone joint, the dermal ecchymosis, arthroncus deformity occur
Deng disease, internal organs are evend penetrate into, the syndrome for internal organs numbness occur.Clinical manifestation is that joint pain or part muscle acid weight are numb, delay
With the passing of time limbs arrested anxious can be caused, very then arthrocele.Caused by wind, cold and wetness evils described in the present invention includes the rheumatic described in modern medicine
Arthritis, rheumatoid arthritis, sciatica, ankylosing spondylitis etc..
Key, is often referred to head or head, and key position is fallen ill, and usually phlegm is turbid to be blinded, or obstruction of the orifices by blood stasis, often shows as refreshing knowledge
Unclear, the disturbance of consciousness, tongue fur is dark violet, thready and hesitant pulse.I.e. when human body is subject to extraneous perverse trend to cause key stasis blocking, then can have a dizzy spell, very
To clouded in mind, need to have one's ideas straightened out in the rules for the treatment of.
The living environment of city fast pace, high pressure, made the pain patients such as wind-cold-dampness arthralgia and was had a dizzy spell in recent years
Puzzlement crowd's incidence of disease present ascendant trend, fall ill Swarm intention rejuvenation.Due to the wind-cold-dampness arthralgia illness course of disease long, at present
It is difficult to effect a radical cure, whenever morbidity is just severely impacted patient's normal life, pain makes patient endure torment to the fullest extent.
【The content of the invention】
Goal of the invention of the invention is：Regarding to the issue above, there is provided a kind of Traditional Chinese medicine used as analgesic composition, dissipated with middle benefit gas
Cold, the dehumidifying of Eradicates wind is stimulated the circulation of the blood and cause the muscles and joints to relax, and the Eradicates stasis of bloods of invigorating blood circulation, swelling and pain relieving, relieving convulsion effect of having one's ideas straightened out is applied to wind-cold-dampness arthralgia, beats the stasis of blood swell
Etc. the various pain for causing, and carbuncle swells, have a dizzy spell, in the medicine of clouded in mind or snake bite and insect sting, present invention also offers this
The preparation method of Chinese medicine composition.
To achieve these goals, the technical solution adopted by the present invention is as follows：
A kind of Traditional Chinese medicine used as analgesic composition, is made up of the raw material of following weight part ratio：Ford dutchmanspipe root or herb 3.5-10.5 parts, climbing fig 3-9
Part, gecko 3-9 parts, laciniate blumea herb 3-9 parts, Chinese hydrangeavine root-bark 3-9 parts, safflower 3-9 parts, frankincense 3-9 parts, myrrh 3-9 parts, teasel root 3-9 parts,
Native copper 3-9 parts, lamiophlomis rotata 3-9 parts, paniculate swallowwort 2.5-7.5 parts, root of Chinese clematis 2.5-7.5 parts, notopterygium root 2-6 parts, levisticum 2-6 parts,
Radix Angelicae Sinensis 2-6 parts, turpentine 2-6 parts, root of Dahurain angelica 1-3 parts, borneol 1-3 parts and menthol 0.5-1.5 parts.
Optimization, it is made up of the raw material of following weight part ratio：Ford dutchmanspipe root or herb 5-9 parts, climbing fig 4.8-7.2 parts, gecko 4.8-7.2
Part, laciniate blumea herb 4.8-7.2 parts, Chinese hydrangeavine root-bark 4.8-7.2 parts, safflower 4.8-7.2 parts, frankincense 4.8-7.2 parts, myrrh 4.8-7.2 parts,
Teasel root 4.8-7.2 parts, native copper 4.8-7.2 parts, lamiophlomis rotata 4.8-7.2 parts, paniculate swallowwort 4-6 parts, root of Chinese clematis 4-6 parts, notopterygium root
3.2-4.8 parts, levisticum 3.2-4.8 parts, Radix Angelicae Sinensis 3.2-4.8 parts, turpentine 3.2-4.8 parts, root of Dahurain angelica 1.6-2.4 parts, borneol 1.6-2.4
Part and menthol 0.8-1.2 parts.
More optimize, be made up of the raw material of following weight part ratio：7 parts of ford dutchmanspipe root or herb, 6 parts of climbing fig, 6 parts of gecko, laciniate blumea herb 6
Part, 6 parts of Chinese hydrangeavine root-bark, 6 parts of safflower, 6 parts of frankincense, 6 parts of myrrh, 6 parts of teasel root, 6 parts of native copper, 6 parts of lamiophlomis rotata, 5 parts of paniculate swallowwort, prestige
1 part of 5 parts of medicine xiaolingxian, 4 parts of notopterygium root, 4 parts of levisticum, 4 parts of Radix Angelicae Sinensis, 4 parts of turpentine, 2 parts of the root of Dahurain angelica, 2 parts of borneol and menthol.
Re-optimization, the native copper is processed product pyritum ignited, and Radix Angelicae Sinensis is selected from Radix Angelicae Sinensis tail.
A kind of preparation method of above-mentioned Traditional Chinese medicine used as analgesic composition, is mainly made up of following steps：By weight, first will be upper
State all raw materials to crush respectively, be well mixed, obtain mixed-powder；Then take and mixed described in the solvent soaking containing certain alcohol concentration
Powder is closed, filtrate is finally collected, filtrate alcohol concentration is adjusted, Traditional Chinese medicine used as analgesic composition is obtained final product.
Optimization, the solvent is selected from one or more in ethanol, white wine, rice wine and yellow rice wine, the alcohol of the solvent
Concentration is 55-75wt%.
More optimize, the consumption of the solvent is that 6-15 times of the mixed-powder weight is measured by weight.
Further optimize, adjustment filtrate alcohol concentration is 30-40wt%.
Further optimize, Traditional Chinese medicine used as analgesic composition is further made form of Chinese drug, the form of Chinese drug be selected from tincture,
One kind in vina, spray, film, pill, paste, liniment and tablet.
Further optimize again, preparing wind-cold-dampness arthralgia, to beat the stasis of blood swell etc. and apply in the various pain medications for causing；And
Applied in the medicine of clouded in mind, skin measles toxicity and/or snake bite and insect sting.
The medicine Main Function used in the present invention (is selected from as follows《Dictionary of medicinal plant》)：
1st, ford dutchmanspipe root or herb：It is warm in nature.Function：Dispelling wind and eliminating dampness, subdhing swelling and detoxicating.Cure mainly：Heart peratodynia, treating rheumatic ostealgia, traumatic injury,
Child convulsion, venomous snake bite.
2nd, climbing fig：Also known as Boston ivy, it is mild-natured.Function：Dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels, removing toxicity for detumescence.Cure mainly：Arthralgia pain due to rheumatism,
Sciatica, amenorrhoea, postpartum blood stasis stomachache, dysmenorrhoea, ulcerative carbuncle pyogenic infections, traumatic injury.
3rd, gecko：It is cold in nature.Function：Dispelling wind and relieving convulsion, detoxicating and resolving a mass.Cure mainly：The apoplexy frightened spare time, severe and wadering arthralgia bitterly, lockjaw, carbuncle
Sore, scrofula, pestilential wind, wind tinea is dysphagic.
4th, laciniate blumea herb：Also known as winged mountain tiger, slightly warm in nature.Function：Dispelling wind and removing obstruction in the meridians, removing toxic substances.Cure mainly：Head wind headache, wind-cold-dampness arthralgia,
Joint pain, traumatic injury, carbuncle swells boil, eczema, snakebite.
5th, Chinese hydrangeavine root-bark：Also known as black tiger, it is warm in nature.Function：Scattered stasis, remove obstruction in channels to relieve pain.Stomachache is cured mainly, arthralgia pain due to rheumatism falls
Beat and damage, fracture, dysmenorrhoea, postpartum blood stasis stomachache, hernia pain.
6th, safflower：It is warm in nature.Function：Invigorate blood circulation, stasis-dispelling and pain-killing.Cure mainly blood stasis, Amenorrhea, dysmenorrhoea, postpartum stasis stomachache, chest
The pained , lumps in the chest and abdomen of numbness, traumatic injury, arthralgia, hemiplegia, macula.
7th, frankincense：It is warm in nature.Function：Blood-activating and qi-promoting, relieves pain myogenic.Cure mainly trusted subordinate's pain, amenorrhoea, dysmenorrhoea, the stagnant abdomen of the postpartum stasis of blood
Bitterly, bruise stasis caused pain, swollen ulcer drug, unhealing ulcer, ruptured abscess resistant to healing.
8th, myrrh：It is mild-natured.Function：Dissolving stasis, detumescence, analgesic therapy.Cure mainly chest and abdomen bitterly, dysmenorrhoea, Amenorrhea , Disorder lumps in the abdomen, treating swelling and pain by traumatic injury, carbuncle
Swollen sore, red eye, swell pain.
9th, teasel root：Slightly warm in nature.Function：Blood vessels, only uterine bleeding are adjusted in filling liver kidney, strengthening the bones and muscles.Cure mainly aching pain in waist and back, podomere Impotence numbness,
Fall and flutter wound, damage muscle folding bone, ulcer sore swells.
10th, native copper：It is mild-natured.Function：Blood stasis removing analgesic, reunion of fractured tendons and bones.Traumatic injury is cured mainly, breaking of muscle and tendon is fractured, and the stasis of blood is stagnant to swell and ache.
Pyritum ignited, is the processed product of native copper, and concocting method presses version in 2015《Chinese Pharmacopoeia》Relevant criterion is carried out under.
11st, lamiophlomis rotata：It is mild-natured.Function：It is promoting blood circulation and removing blood stasis, swelling and pain relieving.Cure mainly bruise, arthralgia and myalgia, painful swelling of joints, pain
Through uterine bleeding.
12nd, notopterygium root：It is warm in nature.Function：Dissipate exterior cold, Eradicates rheumatism, sharp joint, analgesic.Cure mainly and catch cold, lossless, wind of having a headache
Cold-dampness numbness, geomantic omen edema, sore swollen toxin.
13rd, levisticum：It is mild-natured.Function：Expelling wind and eliminating dampness, eliminating cold to stop pain.Cure mainly wind-cold-dampness arthralgia, lumbocrural pain, dentalgia of having a headache.
14th, the root of Dahurain angelica：It is warm in nature.Function：Dispelling wind and eliminating dampness, sensible analgesic, detumescence and apocenosis.Cure mainly cold headache, pain in the supra-orbital bone, tooth
Bitterly, have a stuffy nose, nasosinusitis, wet victory chronic diarrhea, leukorrhea with reddish discharge, ulcer sores.
15th, paniculate swallowwort：It is warm in nature.Function：Dispelling wind and eliminating dampness, the promoting flow of qi and blood circulation is unsting antipruritic.Cure mainly arthralgia pain due to rheumatism, pain in the back, gastral cavity abdomen
Pain, toothache, the pain of injury caused by falling and tumbling, eczema, nettle rash, venomous snake bite.
16th, turpentine：It is warm in nature.Function:Wind-dispelling, eliminating dampness, relaxing muscles and tendons is active, analgesic.Wind-cold-dampness arthralgia is cured mainly, severe and wadering arthralgia bitterly, is had a cramp
Contraction urgency, pin numbness impotence is soft, arthroncus of knee injuries from falls as well.
17th, the root of Chinese clematis：It is warm in nature.Function:Dispelling wind and eliminating dampness, removes obstruction in channels to relieve pain.Cure mainly arthralgia pain due to rheumatism, extremity numbness, spasm of muscles and vessels,
Joint stuffiness, tinea pedis swells and ache.
18th, Radix Angelicae Sinensis tail：It is warm in nature.Function:《Herbal justice》' return body master to keep, mend intrinsic work(, return tail master to lead to, by the stasis of blood certainly
Test ... '.Irregular menstruation is cured mainly, Amenorrhea, dysmenorrhoea , Disorder lumps in the abdomen knot gathers, Impotence numbness, numbness, injury from falling down.
19th, borneol：Cold nature.Function inducing resuscitation of having one's ideas straightened out, radiating analgesic, shade removing.Cure mainly apoplexy lockjaw, pyreticosis coma,
Frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, carbuncle swells, hemorrhoid.
20th, menthol：It is cool in nature.Function dispelling wind, heat-clearing.Anemopyretic cold is cured mainly, is had a headache, hot eyes, abscess of throat, dentalgia, skin
Skin itch.
In sum, by adopting the above-described technical solution, the beneficial effects of the invention are as follows：
The present invention, according to there is pain, is that, because passages through which vital energy circulates is obstructed, human body locally cannot normally moisten foster, not Rong Ze pains mostly
The traditional Chinese medical science is instructed, it has been investigated that patient causes QI-blood circulation to be obstructed because of damp evil invasion body of having a cold, dyshaemia cannot be timely
Cure and produce pain, the course of disease is more long more touching refractory；Or some patientss body is once locally subject to physical shock, causes the stasis of blood
Swollen, occupy-place compressing cannot be mediated in time, caused passages through which vital energy circulates to be obstructed or stop and caused part to cannot get normal blood oxygen supply and produce pain
Bitterly.The present invention is formed using the cooperation of 20 taste Chinese medicines altogether, and jointly with good warming spleen and stomach for dispelling cold, the dehumidifying of Eradicates wind is stimulated the circulation of the blood and cause the muscles and joints to relax, and is invigorated blood circulation
The Eradicates stasis of bloods, swelling and pain relieving, relieving convulsion effect of having one's ideas straightened out can effectively dispel new and old wind-cold-dampness arthralgia in human body, fundamentally cure because of chill
The various pain that arthritis with fixed pain caused by dampness causes, the stasis of blood caused by traumatic injury swells, new and old pain has good efficacy；Wind-heat poison gas is caused simultaneously
Skin measles toxicity, because head key be obstructed cause have a dizzy spell, it is clouded in mind, snake bite and insect sting etc. also has treats or aids in auxiliary very well
Help effect.Chinese medicine composition of the present invention can be used for the exclusive use of above-mentioned illness or use cooperatively.
Totally 20 taste medicine Chinese medicines are constituted Chinese medicine composition of the present invention, and its matching relationship is as follows：First, lead in the present composition
City tiger, climbing fig, laciniate blumea herb, Chinese hydrangeavine root-bark, safflower, frankincense, myrrh, native copper, lamiophlomis rotata, teasel root, notopterygium root, the root of Dahurain angelica, paniculate swallowwort, pine
Section, the root of Chinese clematis, Radix Angelicae Sinensis (Radix Angelicae Sinensis tail) be property of medicine warm nature, with the use of with good promoting blood circulation, promoting qi circulation and relieving pain effect, can have
The qi and blood fortune that effect is dispelled caused by the retardance of human body internal cause wind-cold-dampness arthralgia or hemostasis resistance is obstructed, dyshaemia, so as to fundamentally control
More because of the disease of the pain caused by wind-cold-dampness arthralgia retardance or hemostasis resistance.Levisticum, lamiophlomis rotata, myrrh can also promoting qi circulation and relieving pain, help evil poison to arrange
Go out external.Secondly, in the present composition gecko, the root of Dahurain angelica, borneol and the taste Chinese medicine of menthol three with the use of have dispelling wind and heat from the body,
Have one's ideas straightened out relieving convulsion effect, assist cold-evil and/or stasis blocking to excrete, while can also treat being blinded because phlegm is turbid or obstruction of the orifices by blood stasis causes
Have a dizzy spell, the illness such as obnubilation, with relieving convulsion effect of having one's ideas straightened out；Subcutaneous measles toxicity can also be dismissed, to skin nettle rash or mistake
The disease treatment that quick, rash is itched can play good efficacy.3rd, ford dutchmanspipe root or herb, laciniate blumea herb, paniculate swallowwort are all snakebite in the present composition
Key medicine, in the presence of we have dredging stasis blocking, the evil numbness of discharge very well, the addition of this three tastes snakebite key medicine can be treated effectively
The wound of snakeworm, plus outwards mediated in wound with snakeworm and reach and suppress the purpose that the poison of snakeworm spreads.4th, containing in we
Have the ethanol solution or wine of certain alcohol concentration as solvent, preferably white wine, in addition solvent have in itself sterilization, wind dispelling cold dispelling and
Promoting blood circulation effect, helps the power of medicine row diverging, synergy to heighten the effect of a treatment.The careful conjunction of Chinese medicine composition prescription compatibility of medicines structure of the present invention
Reason, synergy, therefore with effect it is good.
Present invention also offers the preparation method of the Chinese medicine composition, the preparation method has simple, easily controllable, repetition
Property is good, it is adaptable to various dosage scale production and applications.
【Specific embodiment】
With reference to embodiment, the invention will be further described.
First, formulation Example
Embodiment 1
A kind of Traditional Chinese medicine used as analgesic composition, is made up of the raw material of following weight part ratio：3.5 parts of ford dutchmanspipe root or herb, 3 parts of climbing fig, gecko 3
Part, 3 parts of laciniate blumea herb, 3 parts of Chinese hydrangeavine root-bark, 3 parts of safflower, 3 parts of frankincense, 3 parts of myrrh, 3 parts of teasel root, 3 parts of native copper, 3 parts of lamiophlomis rotata, Xu
2.5 parts of minister in ancient times long, 2.5 parts of the root of Chinese clematis, 2 parts of notopterygium root, 2 parts of levisticum, 2 parts of Radix Angelicae Sinensis, 2 parts of turpentine, 1 part of the root of Dahurain angelica, 1 part of borneol and menthol
0.5 part.
Embodiment 2
A kind of Traditional Chinese medicine used as analgesic composition, is made up of the raw material of following weight part ratio：10.5 parts of ford dutchmanspipe root or herb, 9 parts of climbing fig, gecko
9 parts, 9 parts of laciniate blumea herb, 9 parts of Chinese hydrangeavine root-bark, 9 parts of safflower, 9 parts of frankincense, 9 parts of myrrh, 9 parts of teasel root, 9 parts of native copper, 9 parts of lamiophlomis rotata,
7.5 parts of paniculate swallowwort, 7.5 parts of the root of Chinese clematis, 6 parts of notopterygium root, 6 parts of levisticum, 6 parts of Radix Angelicae Sinensis, 6 parts of turpentine, 3 parts of the root of Dahurain angelica, 3 parts of borneol and peppermint
1.5 parts of brain.
Embodiment 3
A kind of Traditional Chinese medicine used as analgesic composition, is made up of the raw material of following weight part ratio：5.6 parts of ford dutchmanspipe root or herb, 4.8 parts of climbing fig, wall
4.8 parts of tiger, 4.8 parts of laciniate blumea herb, 4.8 parts of Chinese hydrangeavine root-bark, 4.8 parts of safflower, 4.8 parts of frankincense, 4.8 parts of myrrh, 4.8 parts of teasel root, nature
4.8 parts of copper, 4.8 parts of lamiophlomis rotata, 4 parts of paniculate swallowwort, 4 parts of the root of Chinese clematis, 3.2 parts of notopterygium root, 3.2 parts of levisticum, 3.2 parts of Radix Angelicae Sinensis, turpentine 3.2
Part, 1.6 parts of the root of Dahurain angelica, 1.6 parts of borneol and 0.8 part of menthol.
Wherein, native copper is processed product pyritum ignited, and Radix Angelicae Sinensis is selected from Radix Angelicae Sinensis tail.
Embodiment 4
A kind of Traditional Chinese medicine used as analgesic composition, is made up of the raw material of following weight part ratio：8.4 parts of ford dutchmanspipe root or herb, 7.2 parts of climbing fig, wall
7.2 parts of tiger, 7.2 parts of laciniate blumea herb, 7.2 parts of Chinese hydrangeavine root-bark, 7.2 parts of safflower, 7.2 parts of frankincense, 7.2 parts of myrrh, 7.2 parts of teasel root, nature
7.2 parts of copper, 7.2 parts of lamiophlomis rotata, 6 parts of paniculate swallowwort, 6 parts of the root of Chinese clematis, 4.8 parts of notopterygium root, 4.8 parts of levisticum, 4.8 parts of Radix Angelicae Sinensis, turpentine 4.8
Part, 2.4 parts of the root of Dahurain angelica, 2.4 parts of borneol and 1.2 parts of menthol.
Wherein, native copper is processed product pyritum ignited, and Radix Angelicae Sinensis is selected from Radix Angelicae Sinensis tail.
Embodiment 5
A kind of Traditional Chinese medicine used as analgesic composition, is made up of the raw material of following weight part ratio：7 parts of ford dutchmanspipe root or herb, 6 parts of climbing fig, gecko 6
Part, 6 parts of laciniate blumea herb, 6 parts of Chinese hydrangeavine root-bark, 6 parts of safflower, 6 parts of frankincense, 6 parts of myrrh, 6 parts of teasel root, 6 parts of native copper, 6 parts of lamiophlomis rotata, Xu
1 part of 5 parts of minister in ancient times long, 5 parts of the root of Chinese clematis, 4 parts of notopterygium root, 4 parts of levisticum, 4 parts of Radix Angelicae Sinensis, 4 parts of turpentine, 2 parts of the root of Dahurain angelica, 2 parts of borneol and menthol.
Wherein, native copper is processed product pyritum ignited, and Radix Angelicae Sinensis is selected from Radix Angelicae Sinensis tail.
2nd, preparation method embodiment
Embodiment 6
The preparation method of Traditional Chinese medicine used as analgesic composition, is mainly made up of following steps described in a kind of any one of embodiment 1-5：
By weight, first above-mentioned all raw materials are crushed respectively, is well mixed, obtain mixed-powder；Then take and contain one
Determine mixed-powder described in the solvent soaking of alcohol concentration, filtrate is finally collected using percolation, adjustment filtrate alcohol concentration is
30wt%, obtains final product Traditional Chinese medicine used as analgesic composition.
Wherein, solvent is selected from ethanol, and the alcohol concentration of the solvent is 55wt%.The consumption of the solvent by weight,
It is 6 times of amounts of the mixed-powder weight.
Further, take Traditional Chinese medicine used as analgesic composition and be further made form of Chinese drug, the form of Chinese drug is selected from tincture.
Embodiment 7
The preparation method of Traditional Chinese medicine used as analgesic composition, is mainly made up of following steps described in a kind of any one of embodiment 1-5：
By weight, first above-mentioned all raw materials are crushed respectively, is well mixed, obtain mixed-powder；Then take and contain one
Mixed-powder described in determining the solvent soaking of alcohol concentration, finally collects filtrate, and adjustment filtrate alcohol concentration is 40wt%, is obtained final product only
Pain Chinese medicine composition.
Wherein, solvent is selected from white wine, and the alcohol concentration of the solvent is 75wt%.The consumption of the solvent by weight,
It is 15 times of amounts of the mixed-powder weight.
Further, take Traditional Chinese medicine used as analgesic composition and be further made form of Chinese drug, the form of Chinese drug is selected from vina.
Embodiment 8
The preparation method of Traditional Chinese medicine used as analgesic composition, is mainly made up of following steps described in a kind of any one of embodiment 1-5：
By weight, first above-mentioned all raw materials are crushed respectively, is well mixed, obtain mixed-powder；Then take and contain one
Mixed-powder described in determining the solvent soaking of alcohol concentration, finally collects filtrate, and adjustment filtrate alcohol concentration is 35wt%, is obtained final product only
Pain Chinese medicine composition.
Wherein, solvent is selected from the mixture of white wine and rice wine, and the alcohol concentration of the solvent is 60wt%.The solvent
Consumption is 8 times of amounts of the mixed-powder weight by weight.
Further, take Traditional Chinese medicine used as analgesic composition and be further made form of Chinese drug, the form of Chinese drug is selected from spray.
It is appreciated that solvent is arbitrarily arranged in pairs or groups in being selected from yellow rice wine, or ethanol, rice wine, white wine in the present invention, simply different solvents
There is some difference for the effect of the extract for obtaining, but can realize purpose of the present invention by extracts active ingredients out.
It is appreciated that form of Chinese drug of the present invention can also Traditional Chinese medicine used as analgesic composition that routinely pharmaceutical technology obtains the present invention
Further it is made any one in film, pill, paste, liniment and tablet.
3rd, Application Example
The purposes of the Traditional Chinese medicine used as analgesic composition described in a kind of utilization embodiment any one of 1-5, it is characterised in that preparing wind
Cold-dampness numbness, to beat the stasis of blood swell etc. and apply in the various pain medications for causing；And obnubilation, skin measles toxicity and/or snake bite and insect sting
Applied in medicine.
4th, with effect test
It is prepared by test specimen：Selection embodiment 5 is formulated and is prepared into tincture according to the method for embodiment 8.It is appreciated that real
Applying any one of 1-5 can be prepared according to embodiment 6-8 methods, and simply curative effect has part variation, but not influence this
The implementation of The effect of invention.
Use taboo：Pregnant woman and alcohol intolerance person avoid use, avoid entrance eye, and wound is used with caution.
(1) curative effect pain caused to wind-cold-dampness arthralgia
1st, case selection：Selection carries out medication observation because wind-cold-dampness arthralgia causes the patient 30 of pain.Selection patient
Inclusion criteria：Because being subject to the wet invasion and attack of chill, cause the qi and blood fortune caused by stagnation of QI-blood or stasis blocking to be obstructed, dyshaemia and produce
Pain.Rheumatic arthritis, rheumatoid arthritis described in modern medicine, sciatica, shoulder enclose the diseases such as inflammation, cervical spondylopathy
Disease.
2nd, treatment method：Tincture is sprayed directly on to affected part to patient, three times a day, spray 3-5 times, is covered after spray with film every time
Lid affected part is better.Case patient is not belonging to use the listed situation of taboo.
3rd, Outcome measure：
(1) cure：Painful recovery, pain disappears or extremely slight, there is lasting improvement trend.
(2) it is effective：Pain relatively mitigates before, and take a favorable turn trend.
(3) it is invalid：Pain does not relatively have any improvement before, still very bitterly.
4th, treatment rate：
By the way that 30 patients are carried out with lasting tracking treatment, it is 19 people that the patient for curing is had after medication 0.5-4 month, is shown
Imitate 6 people, the people of refractory patient 5, cure rate 63.3%, obvious effective rate 20%, up to 83.3%, other people are because choosing then patient for total effective rate
When, not exclusively coincideing or have other illnesss concurrently because of the cause of disease causes pain, and this Chinese medicine composite tincture, can be with the case where suiting the medicine to the illness
There is extraordinary therapeutic effect to patient.
5th, model case citing：
Lee, female, 35 years old, Guangxi Donglan County, professional aquaculture.Because for a long time receive damp evil and attacked by the cold and evil, swivel of hand and
Foot joint seasonality pain, long-term treatment is not cured, limitation of activity when serious.Tincture of the present invention is persistently sprayed after 3 months, and pain is bright
It is aobvious to mitigate, can normal activity, and have lasting improvement trend, cured substantially.
Yuan, man, 27 years old, Longzhou people from county, conceptual design work.Because of long campaigns design, to the computer work time
Too long, activity is lacked, with cervical spondylopathy.Tincture of the present invention is persistently sprayed after 0.5 month, and symptom substantially mitigates, and has been controlled after 1 month
More.
Chen, female, 49 years old, people from Guangxi Hechi, professional peasant.Because of long-term work, damp evil of having a cold puzzlement, rheumatism 4 years
Have a surplus, during seasons change, the pain increased, influence daily life.Tincture of the present invention is persistently sprayed after 3.5 months, and pain substantially mitigates,
And have lasting improvement trend, and it is continuing with to after 4 months, cure substantially, do not recurred in 2 years.
(2) to the curative effect of new and old pain caused by beating the stasis of blood swell
1st, case selection：Selection beats the stasis of blood swell caused new and old pain pain.Selection patient selection's standard：Because being damaged by external force
Hinder or because beating the stasis of blood swell pain caused patient.
2nd, treatment method：Tincture is sprayed directly on to affected part to patient, three times a day, spray 3-5 times, is covered after spray with film every time
Lid affected part is better.
3rd, Outcome measure：
(1) cure：Painful recovery, pain disappears or extremely slight, there is lasting improvement trend.
(2) it is effective：Pain relatively mitigates before, and take a favorable turn trend.
(3) it is invalid：Pain does not relatively have any improvement before, still very bitterly.
4th, treatment rate：
By the way that 15 patients are carried out with lasting tracking treatment, medication has the patient for curing after 7-90 days be 10 people, effective 2
People, the people of refractory patient 3, cure rate 66.7%, obvious effective rate 13.3%, total effective rate up to 80%, other people because choosing then patient when,
Other illnesss are not exclusively coincide or had concurrently because of the cause of disease causes pain, and this Chinese medicine composite tincture, can be right in the case where suiting the medicine to the illness
Patient has extraordinary therapeutic effect.
5th, model case citing：
It is deep certain, man, 40 years old, Guigang great Xu Zhen Cheung On Est. people.Patient on October 2nd, 2016, because having some setbacks by motorcycle
Overturn, face portion Butt wounds, the stasis of blood is swollen to cause face gross distortion, and EVAC HOSP film making diagnosis is controlled without just being gone home after fracture with tincture of the present invention
Treat, spray three to four times, return to normal for four days daily, tight hemostasis all disappears for seven days；It is continuing with tincture of the present invention 30,
Wound without pain, does not recur so far.
Wei, man, 72 years old.Guigang great Xu Zhen Dong Huang people from villages.Patient is on March 12nd, 2015 in careless traffic accident the year before
Left anklebone folding comminuted fracture is caused, is discharged to home after school's hospitalization so far, wound cannot heal always, ooze out yellow water not
It is disconnected, step is carried out by crutch is difficult, treated with tincture of the present invention afterwards, after 25 days, wound healing；It is no longer rely on turning after three months
Cane is walked, and function is recovered substantially, and has lasting improvement sign.
Zhu, man, 50 years old, people from Guigang, professional civil servant.Patient once once opened cranium treatment because of serious cerebral injury, went home
Upper limbs is twitched to take place frequently 1 year and is had a surplus afterwards, and in May, 2014 is treated using tincture of the present invention, is sprayed when often to be taken out, and uses disease after 3 months
Shape is relieved, and tic is significantly reduced, basic to cure；All disappeared to prevent recurrence to be continuing with to after 5 months symptom, so far
Do not recur.
(3) to snake bite and insect sting, obnubilation, skin measles toxicity patient curative effect
Model case is illustrated：
1. snake bite and insect sting patient curative effect model case：
Hu, man, 24 years old.Guigang great Xu Zhen Cheung On Est. people.Patient plucks when the morning 10 on the 28th of July in 2016 in vegetable plot
Accidentally by Induced By Coral Snake Bite RIF during dish, patient's emergency diagnosis and treatment reserve wound and spray from top to bottom with tincture of the present invention, while
Directly arrive in first-aid centre of city after being cleaned a wound with clear water, hospital emergency center has been remained in a hospital under observation 48 hours in city, after without occur not
Leave hospital after good symptom.
2. stupor, clouded in mind patient's curative effect model case：
It is deep certain, female, 75 years old, peasant.Guangxi Guigang great Xu Zhen folk musics people from village.Patient is confused suddenly in evening in April, 2015
Faint, lip cyanosis are looked pale, and sweating is dripping, senseless, area is each before and after the tincture spray patient chest heart of the present invention of urgent need at that time
Spray 5 times, while calling 120 first-aid centres, revived after patient's spray less than 3 minutes, and each sign is as usual after waking up.
It is deep certain, female, 83 years old, Guigang port cities and towns Lam Tin Est. people.Stupor l entered on May 3rd, 2015 after patient suffers from angina pectoris
Port north hospital is treated 5 days, and Hou Zhuan cities hospital is not improved for 10 days, and the state of an illness is more weighed, and school's suggestion goes home to process funeral affairs.
Through looking into BP76x42, arrhythmia, heart sound is low blunt faint, remains unconscious, for example dead color in face, heart extreme exhaustion, let go at any time and
Go.Area respectively sprays 5 times before and after spraying the heart with tincture of the present invention after the observation state of an illness, and 10 minutes or so after spray, patient's heart sound improves, beating
Slight force, after take blood pressure and risen to 82 × 54, at this moment patient's expression takes a turn for the better, and re-uses tincture of the present invention afterwards after an hour,
During afternoon three, patient comes to life, and can enter half bowl of congee, then through herbal treatment, and coordinate tincture to use, patient's energy after 5 months
Take care of oneself, sign is as before.
3. skin measles toxicity patient curative effect model case：
Zeng, female, 48 years old, Guigang great Xu Zhen Shi Gu people from villages.Patient tells that head is suffered from the year before and lost after bleb leaves more afterwards
Disease, severe pain, it is impossible to which work and rest, and left vision degradation, eye upper eyelid are slightly sagging, very painful, afterwards with this
Invention tincture sprays affected part treatment, daily 3-4 times, every time spray 4-5 times, and severe pain is alleviated, and health after 1.5 months is persistently used afterwards
It is multiple.
Not certain, female, 38 years old, people from Liuzhou.Patient suffers from urticaria perstans 13 years, breaks out frequently, particularly eat beef or
High protein diet is breaking-out, and whole body pimple during breaking-out, block rash company time, itch is unbearably, very painful.Controlled using tincture of the present invention
Treat, daily 3-4 times, spray 4-5 times every time, symptom disappears after 1.5 months, is not broken out 2 years so far more.
It is blue certain, man, 42 years old, people from Nanning.Patient suffers from pin onychomycosis for many years, is applied with medical cotton dip in liquid medicine with tincture of the present invention suffer from afterwards
Place, daily 2 times, spray 4-5 times every time is fully recovered for 15 days.
Described above is directed to the detailed description of preferably possible embodiments of the invention, but embodiment is not limited to this hair
Bright patent claim, the equal change completed under the technical spirit suggested by all present invention or modification change, all should belong to
Cover the scope of the claims in the present invention.
Claims (10)
1. a kind of Traditional Chinese medicine used as analgesic composition, it is characterised in that be made up of the raw material of following weight part ratio：Ford dutchmanspipe root or herb 3.5-10.5
Part, climbing fig 3-9 parts, gecko 3-9 parts, laciniate blumea herb 3-9 parts, Chinese hydrangeavine root-bark 3-9 parts, safflower 3-9 parts, frankincense 3-9 parts, myrrh 3-9 parts,
Teasel root 3-9 parts, native copper 3-9 parts, lamiophlomis rotata 3-9 parts, paniculate swallowwort 2.5-7.5 parts, root of Chinese clematis 2.5-7.5 parts, notopterygium root 2-6 parts,
Levisticum 2-6 parts, Radix Angelicae Sinensis 2-6 parts, turpentine 2-6 parts, root of Dahurain angelica 1-3 parts, borneol 1-3 parts and menthol 0.5-1.5 parts.
2. a kind of Traditional Chinese medicine used as analgesic composition according to claim 1, it is characterised in that by the raw material group of following weight part ratio
Into：Ford dutchmanspipe root or herb 5-9 parts, climbing fig 4.8-7.2 parts, gecko 4.8-7.2 parts, laciniate blumea herb 4.8-7.2 parts, Chinese hydrangeavine root-bark 4.8-7.2 parts, it is red
Flower 4.8-7.2 parts, frankincense 4.8-7.2 parts, myrrh 4.8-7.2 parts, teasel root 4.8-7.2 parts, native copper 4.8-7.2 parts, lamiophlomis rotata
4.8-7.2 parts, paniculate swallowwort 4-6 parts, root of Chinese clematis 4-6 parts, notopterygium root 3.2-4.8 parts, levisticum 3.2-4.8 parts, Radix Angelicae Sinensis 3.2-4.8 parts,
Turpentine 3.2-4.8 parts, root of Dahurain angelica 1.6-2.4 parts, borneol 1.6-2.4 parts and menthol 0.8-1.2 parts.
3. a kind of Traditional Chinese medicine used as analgesic composition according to claim 1, it is characterised in that by the raw material group of following weight part ratio
Into：7 parts of ford dutchmanspipe root or herb, 6 parts of climbing fig, 6 parts of gecko, 6 parts of laciniate blumea herb, 6 parts of Chinese hydrangeavine root-bark, 6 parts of safflower, 6 parts of frankincense, 6 parts of myrrh, teasel root
6 parts, 6 parts of native copper, 6 parts of lamiophlomis rotata, 5 parts of paniculate swallowwort, 5 parts of the root of Chinese clematis, 4 parts of notopterygium root, 4 parts of levisticum, 4 parts of Radix Angelicae Sinensis, 4 parts of turpentine,
1 part of 2 parts of the root of Dahurain angelica, 2 parts of borneol and menthol.
4. a kind of Traditional Chinese medicine used as analgesic composition according to claim any one of 1-3, it is characterised in that the native copper is big gun
Product pyritum ignited, Radix Angelicae Sinensis is selected from Radix Angelicae Sinensis tail.
5. the preparation method of Traditional Chinese medicine used as analgesic composition described in a kind of any one of claim 1-3, it is characterised in that main by following
Step is made：By weight, first above-mentioned all raw materials are crushed respectively, is well mixed, obtain mixed-powder；Then take and contain one
Mixed-powder described in determining the solvent soaking of alcohol concentration, finally collects filtrate, adjusts filtrate alcohol concentration, obtains final product Traditional Chinese medicine used as analgesic group
Compound.
6. the preparation method of a kind of Traditional Chinese medicine used as analgesic composition according to claim 5, it is characterised in that the solvent is selected from
One or more in ethanol, white wine, rice wine and yellow rice wine, the alcohol concentration of the solvent is 55-75wt%.
7. a kind of preparation method of Traditional Chinese medicine used as analgesic composition according to claim 5, it is characterised in that the use of the solvent
Amount is that 6-15 times of the mixed-powder weight is measured by weight.
8. a kind of preparation method of Traditional Chinese medicine used as analgesic composition according to claim 5, it is characterised in that adjustment filtrate alcohol
Concentration is 30-40wt%.
9. the preparation method of a kind of Traditional Chinese medicine used as analgesic composition according to claim 5, it is characterised in that Traditional Chinese medicine used as analgesic is combined
Thing is further made form of Chinese drug, and the form of Chinese drug is selected from tincture, vina, spray, film, pill, paste, liniment and piece
One kind in agent.
10. the purposes of the Traditional Chinese medicine used as analgesic composition described in a kind of any one of claim 1-3, it is characterised in that preparing chill
Arthritis with fixed pain caused by dampness, to beat the stasis of blood swell etc. and apply in the various pain medications for causing；And the medicine of clouded in mind, skin measles toxicity and/or snake bite and insect sting
Applied in thing.
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| CN104208580B (en) * | 2014-08-27 | 2017-09-12 | 孙仁棉 | It is a kind of to treat Chinese medicine composition for the treatment of rheumatic ostealgia and preparation method thereof |
| CN105011659A (en) * | 2015-06-30 | 2015-11-04 | 汤艳娥 | U-shaped pillow containing Chinese medicine |
| CN105902634A (en) * | 2016-06-03 | 2016-08-31 | 广西玉林市易源堂生物科技有限责任公司 | Plaster for treating pain of neck, shoulder, waist and leg |
-
2017
- 2017-01-20 CN CN201710047085.2A patent/CN106692334A/en active Pending
- 2017-05-22 CN CN201710362751.1A patent/CN106985719A/en active Pending
- 2017-06-26 CN CN201710491429.9A patent/CN107137471A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN107137471A (en) | 2017-09-08 |
| CN106985719A (en) | 2017-07-28 |
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Application publication date: 20170524 |