CN106937966A - Nourishing the stomach cream and preparation method thereof - Google Patents
Nourishing the stomach cream and preparation method thereof Download PDFInfo
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/30—Extraction of the material
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2236/50—Methods involving additional extraction steps
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Abstract
The present invention relates to the field of Chinese medicines, and more particularly to a kind of nourishing the stomach cream and preparation method thereof.The nourishing the stomach cream is made up of plurality of raw materials.In parts by weight, above-mentioned plurality of raw materials includes 15 25 parts of honey, 0.5 0.8 parts of alums, 0.8 1.5 parts of sodium bicarbonate, 12 parts of roots of kudzu vine, 0.5 1.5 parts of Poria cocos and 0.8 1.2 portions of Radix Glycyrrhizaes.Each raw material collective effect regulation stomach function of the nourishing the stomach cream, regulation gastric acid secretion, protection stomach lining, promotion gastrointestinal motility promote gastric acid secretion normal stomach formation protection, and suppression pathogen growth lifts body immunity.
Description
Technical field
The present invention relates to the field of Chinese medicines, and more particularly to a kind of nourishing the stomach cream and preparation method thereof.
Background technology
Stomach trouble, is many general designations with stomach relevant disease.They have a similar symptom, such as upper abdomen gastral cavilty portion discomfort, pain,
Glutted after meal, belch, acid reflux, or even Nausea and vomiting etc..Clinically common stomach trouble has acute gastritis, chronic gastritis, stomach to burst
Ulcer, duodenal ulcer, gastroduodenal complex ulcer, polyp of stomach, gastric concretion, the innocent and malignant tumour of stomach, also stomach lining take off
Hang down disease, acute gastric dilatation, pyloric stenosis etc..
In life, because the food that human body is eaten contains the pathogenic bacteria of many, cleaning or high temperature differ surely complete
Remove, meanwhile, compatriots do not have serving chopsticks accustomed to using, one family regardless of tableware so that stomach trouble is difficult recovery from illness, easily recurrence yet.And show
The medicine of some treatment stomach trouble is also only that can only be alleviated for single gastric disease symptoms, and can not a kind of alleviation of medicine it is a variety of
Symptom, meanwhile, therapeutic effect is poor.
The content of the invention
It is an object of the invention to provide a kind of nourishing the stomach cream, its for gastric mucosa damage, helicobacter pylori flora it is exceeded,
Nausea and vomiting, gastric disorder causing nausea, glutted, pain, belch etc. have obvious curative effect caused by hyperhydrochloria etc..
Another object of the present invention is to provide a kind of preparation method of nourishing the stomach cream, can quickly it be prepared by the preparation method
Obtain nourishing the stomach cream.
The present invention is solved its technical problem and realized using following technical scheme：
The present invention proposes a kind of nourishing the stomach cream, and the nourishing the stomach cream is made up of plurality of raw materials.In parts by weight, above-mentioned plurality of raw materials bag
Include 15-25 parts of honey, 0.5-0.8 parts of alums, 0.8-1.5 parts of sodium bicarbonate, the 1-2 parts of roots of kudzu vine, 0.5-1.5 parts of Poria cocos and 0.8-1.2
Part Radix Glycyrrhizae.
The present invention proposes a kind of preparation method of nourishing the stomach cream, comprises the following steps：
In parts by weight, concentration is concentrated to give after the 1-2 parts of roots of kudzu vine, 0.5-1.5 parts of Poria cocos and 0.8-1.2 portions of Radix Glycyrrhizaes being decocted
Liquid.
In a heated condition, after being mixed after 0.5-0.8 parts of alums are mixed with water and concentrate with 15-25 parts of honey, point
Batch adds 0.8-1.5 parts of sodium bicarbonate and is well mixed.
The beneficial effect of nourishing the stomach cream of the present invention is：The nourishing the stomach cream of the present invention using 15-25 parts of honey, 0.5-0.8 parts of alums,
0.8-1.5 parts of sodium bicarbonate, the 1-2 parts of roots of kudzu vine, 0.5-1.5 parts of Poria cocos and 0.8-1.2 parts of Radix Glycyrrhizae collective effect regulation stomach functions, regulation
Gastric acid secretion, protection stomach lining, promotion gastrointestinal motility, promote gastric acid secretion normal stomach formation protection, suppression pathogen growth,
Lift body immunity.Meanwhile, the interaction of each raw material can offset the toxic and side effect of itself or other raw materials, reduce clothes
With the ill symptomses after nourishing the stomach cream, the occurrence probability of ill symptomses is reduced.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, are the conventional production that can be obtained by commercially available purchase
Product.
In the description of the invention, it is necessary to which explanation, term " first ", " second " etc. are only used for distinguishing description, without
It is understood that to indicate or imply relative importance.
Nourishing the stomach cream of the embodiment of the present invention and preparation method thereof is specifically described below.
A kind of nourishing the stomach cream provided in an embodiment of the present invention, the nourishing the stomach cream is made up of plurality of raw materials.In parts by weight, above-mentioned original
Material includes 15-25 parts of honey, 0.5-0.8 parts of alums, 0.8-1.5 parts of sodium bicarbonate, the 1-2 parts of roots of kudzu vine, 0.5-1.5 parts of Poria cocos and 0.8-
1.2 portions of Radix Glycyrrhizaes.Preferably, above-mentioned raw materials include 18-22 parts of honey, 0.5-0.6 parts of alums, 1-1.2 parts of sodium bicarbonate, 1-1.5 parts
The root of kudzu vine, 0.8-1.2 part Poria cocos and 0.8-1.2 portions of Radix Glycyrrhizaes.
When each raw material in nourishing the stomach cream uses aforementioned proportion, the synergy between each component can reach best effective
Really, and above or below the embodiment of the present invention ratio recorded, the effect or function of each component will decrease, while group
/ synergy will also decrease in addition disappear.Alum can be with sodium bicarbonate reaction generation aluminium hydroxide, aluminium hydroxide energy
Hydrochloric acid in gastric juice enough is neutralized using its alkalescence, the problem of reducing gastroxia alleviates stomach pain.Meanwhile, alum has antibacterial
Effect, can suppress the growth of helicobacter pylori, and then play the symptom alleviated and had a stomach-ache.And sodium bicarbonate also has neutralization hydrochloric acid in gastric juice
Effect, further gastric acid secretion inhibiting.But alum has micro- poison, can be detoxified using Radix Glycyrrhizae, reduce nourishing the stomach cream toxicity with
And side effect, while Radix Glycyrrhizae has similar cortex hormone of aadrenaline sample to act on, there is suppression to make to gastroxia caused by histamine
With；And have antiacid and alleviation gastrointestinal smooth muscle spasm effect.Therefore, it can further alleviate the symptom having a stomach upset.Together
When, sodium bicarbonate can produce carbon dioxide after human body and acid reaction, and carbon dioxide triggers gastric acid secretion to stimulate stomach lining
It is many.And the honey added then can prevent stimulation of the carbon dioxide to gastric mucosa to gastric mucosa formation protective layer.The root of kudzu vine, Poria cocos etc.
Also it can be interacted with raw material and alleviate the side effect of single medicine, meanwhile, play itself treatment stomach trouble or alleviate stomach not
Suitable function.And synergy can either play the effect of itself between each raw material, make while the poison for reducing other drugs is secondary
With the therapeutic effect of increase other drugs, common alleviate of plurality of raw materials interaction even treats a variety of stomach symptoms or stomach trouble.
Honey is that honeybee gathers nectar, the yellow-white thick liquid through spontaneous fermentation.Honey, which has, improves blood
Composition, promotes heart and brain and blood vessel function, has maintenance effects for liver, can promote liver regeneration, honey also has the effect of sterilizing
Really.In embodiments of the present invention, the effect of honey is antibacterial, prevents infection, meanwhile, honey can strengthen enterocinesia, shorten row
Just the time, gastrointestinal function is adjusted, promotes gastric acid secretion normal.And a variety of enzymes and mineral matter synergy in honey, it can carry
High immunity, lifting human body reduces damage of the carbon dioxide to gastric mucosa to the resistance of germ.
Alum is the crystallization of the processed refinement of mineral alunite.Main chemical compositions are 12 hydrazine aluminum sulfate potassium.
Mineral matter Chinese medicine, external application can detoxify desinsection, and eliminating dampness is antipruritic；It is interior to use hemostasis, antidiarrheal, resolving sputum.Alum nature and flavor are sour and astringent, tremble with fear, there is micro- poison,
It can eat on a small quantity.The main function of alum is the growth for suppressing helicobacter pylori in embodiments of the present invention, meanwhile, with little Su
Reaction generation aluminium hydroxide is beaten, and then neutralizes hydrochloric acid in gastric juice.
Sodium bicarbonate also known as sodium acid carbonate, are the acid salt generated after highly basic is neutralized with weak acid, alkalescent are presented when being dissolved in water.
Its heated easily decomposition, is slowly decomposed in humid air.Can directly as pharmaceuticals industry raw material, for treating hyperhydrochloria.
In embodiments of the present invention, itself and stomach acid reaction, alleviate the symptoms such as pain, heartburn, vomiting caused by hyperhydrochloria.Meanwhile, with
Alum reaction generation aluminium hydroxide further neutralizes hydrochloric acid in gastric juice.
The root of kudzu vine is the dry root of legume pueraria lobata, practises and claims elegant jessamine.There is expelling pathogenic factors from muscles and skin to bring down a fever for it, and promoting eruption promotes the production of body fluid to quench thirst, rising Yang
Effect of antidiarrheal, available for treatment table card heating, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, spleen
Empty diarrhea.Effect of the root of kudzu vine is to enhance metabolism in embodiments of the present invention, strengthens the function of detoxification of liver, meanwhile, to stomach
Mucosa injury has certain protective effect.
Poria cocos is On Polyporaceae Poria cocos Poria cocos (Schw.) Wolf dry sclerotia.There is Li Shui to ooze for it
It is wet, invigorating the spleen, effect of calming heart.For oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear
Treatment.In embodiments of the present invention Poria cocos can stomach invigorating, carry except the aqueous of retention in stomach, lift WeiDongLi Capsule, it is viscous simultaneously for stomach
Membrane damage has protective effect.
Radix Glycyrrhizae, scientific name：Glycyrrhiza uralensis Fisch alias：State is old, Herba Hedyotis cantonensis, Glycyrrhiza Uralensis, sweet
Son.Pulse family, Glycyrrhiza perennial herb, root are sturdy with root-like stock, are a kind of to the good help Chinese herbal medicine of human body, medicinal part
It is root and rhizome.Radix Glycyrrhizae has similar cortex hormone of aadrenaline sample to act on.There is inhibitory action to gastroxia caused by histamine；
And have antiacid and alleviation gastrointestinal smooth muscle spasm effect.Extract of licorice root has similar glucuronic acid with glycyrrhizic acid to some poisonous substances
Detoxication.In in the present invention is implemented, Radix Glycyrrhizae, which is mainly, can neutralize the property of medicine and drug effect of each medicine.Meanwhile, stomach can be suppressed
Acid secretion, the solution toxicity that medicine has unless each, pain of alleviation in itself has protecting effect to gastric mucosa.
It is further preferred that plurality of raw materials also includes 0.8-1.2 parts of ginsengs.Ginseng (Panax ginseng C.A.Mey)
Fleshy root be famous strong tonic, it is adaptable to adjust blood pressure, recover cardiac function, neurasthenia and the disease such as in poor health,
Also there is the effects such as eliminating the phlegm, stomach invigorating, diuresis, excitement.Ginseng, which is mainly, in embodiments of the present invention can increase the removing toxic substances energy of liver
Power strengthens, so as to strengthen tolerance of the body to various chemical substances.Meanwhile, promote the reparation of gastric mucosa, it is viscous to reduce hydrochloric acid in gastric juice
The damage of film.
It is further preferred that plurality of raw materials also includes 0.8-1.2 portions of dandelions.Dandelion (Taraxacum
Mongolicum Hand.-Mazz.) composite family, Dandelion herbaceos perennial.Contain dandelion in dandelion plant
A variety of health-nutrition compositions such as alcohol, taraxacin, choline, organic acid, synanthrin, available for treatment gastritis, heat toxin, toothache, hot eyes.
It is mainly used for bactericidal antiphlogistic, alleviates stomach pain in embodiments of the present invention, and gastric mucosa formation is protected.
The present invention also provides a kind of method for preparing nourishing the stomach cream：
S1, decoct；
In parts by weight, the 1-2 parts of roots of kudzu vine, 0.5-1.5 parts of Poria cocos and 0.8-1.2 portions of Radix Glycyrrhizaes are respectively crushed into bulk, just
Active ingredient in subsequent extracted solvent-water dissolves raw material, and then lift extraction efficiency and speed.Then will be upper after crushing
State and decocted 2-3 hours at a temperature of 60-85 DEG C after raw material is mixed with 100-120 parts of water.Heated, lifting active ingredient exists
Dissolved efficiency in water, accelerates rate of extraction.But, heat-sensitive substance may be contained in active ingredient, in order to prevent thermal sensitivity
Material goes bad because of high temperature, therefore, is extracted using middle temperature.
It should be noted that the decoction of the root of kudzu vine, Poria cocos and liquorice, can be decocted again after three kinds of raw materials are mixed,
Can be remixed together after 3 kinds of raw materials are decocted respectively, the species and quantity for the material that two kinds of decoction methods are extracted are basic
Unanimously, therefore, the therapeutic effect played is consistent.
It is further preferred that in order to ensure that extraction effect needs repeatedly to extract above-mentioned three kinds of raw materials, it is preferable that carry
It is 2-3 times to take number of times.
Concentrated it is further preferred that above-mentioned three kinds of raw materials then to be decocted to the obtained juice that decocts, the multiple of concentration is
Decoct 1/4-1/6 times of juice total amount.To decoct juice carry out concentration be in order to ensure the root of kudzu vine, Poria cocos, Radix Glycyrrhizae decoct in juice effectively into
The content divided, and then lift the curative effect of nourishing the stomach cream.
S2, mixing；
Under conditions of temperature is 40-60 DEG C, 0.5-0.8 parts of alums, water and above-mentioned concentrate are mixed, specifically
Hybrid mode be that alum is dissolved in into concentrate after water to be mixed.Because alum is solid, it is necessary to first dissolved, alum is molten
Xie Houzai carries out being mixed to get mixed liquor with concentrate.Mixed again with water after can also alum be mixed with concentrate.Due to white
Alum is dissolved in after water easy hydrolysis aluminium ion, aluminium ion and the Strong oxdiative aluminium of aquatic agglutination, the energy of adsorption of alumine hydroxide colloid
Power is very strong, the material easily suspended in absorption water, and forms precipitation.And may be water insoluble effective containing some in concentrate
Composition, or as temperature is reduced, and dissolution is partially soluble in water but the not high active material of solubility.If first by alum with it is dense
Contracting liquid is mixed, then alum easily make it that the insoluble matter in concentrate is settled, the active ingredient in destruction concentrate.And if first
Mixed again with concentrate after alum is mixed with water, alum is first dissolved in the contamination precipitation that will may can contain in water in water, and then
Follow-up alum and the effect of active ingredient in concentrate are reduced, and then ensures the content of active ingredient in whole mixed liquor.
Then above-mentioned mixed liquor is mixed with 15-25 parts of honey, sodium bicarbonate is then added in batches again.Because honey is glutinous
Denseness is difficult greatly uniform with other material mixings.If first by honey and other material mixings, easily cause and mix uneven, and then
Reduce effect of nourishing the stomach cream.And the mobility of water is larger, it is easily well mixed with honey.Simultaneously as sodium bicarbonate and alum
It can be reacted after mixing, and then produce carbon dioxide so that mixed liquor produces substantial amounts of bubble, also be unfavorable for the mixed of sodium bicarbonate
Close uniform, therefore, sodium bicarbonate added in batches, it is ensured that each raw material it is well mixed.The mixture of honey and water it is sticky
Decreased for the relative honey of degree, but viscosity is still very high on the whole, the sodium bicarbonate added in batches can only be with
The mixture on upper strata is well mixed, meanwhile, substantial amounts of bubble is produced, in order to ensure the therapeutic effect of nourishing the stomach cream, upper strata is mixed
Uniform liquid is transferred in another container, sodium bicarbonate is then added again, then be stirred and shift.Liquid after repeatedly shifting
It is also required to be stirred continuously after body mixing, it is ensured that each material mixing is uniform.
Further, the mode of addition sodium bicarbonate is that 0.015-0.03 parts of sodium bicarbonate are added into honey with mixing in batches
In liquid and it is stirred, substantial amounts of bubble will be now produced, by supernatant liquid as bubble is transferred to another storage container together
In, then it is then added to 0.015-0.03 parts of sodium bicarbonate and repeats the above steps.Stir mixing for the supernatant liquid in storage container
Compound, until bubble hour, and carry out natural cooling.Further, the process entirely heated continues 1-3 hours, during the heating
Between alum, water, concentrate, honey and sodium bicarbonate can be well mixed, simultaneously, it is ensured that contain in nourishing the stomach cream it is effective into
The content divided, and its effect is optimal.
The nourishing the stomach cream of the present invention, stomach function can be effectively adjusted using material based on honey, promote gastric acid secretion
Normally, pathogen growth is suppressed, while lifting body immunity.Pass through honey, alum, sodium bicarbonate, the root of kudzu vine, Poria cocos and liquorice simultaneously
Interaction, jointly adjust gastric acid secretion, protection stomach lining, promote gastrointestinal motility, to stomach formation protect.Meanwhile, each
Raw material interaction can offset the toxic and side effect of itself or other raw materials, and the ill symptomses after nourishing the stomach cream are taken in reduction, drop
The occurrence probability of low ill symptomses.
The feature and performance to the present invention are described in further detail with reference to embodiments.
Embodiment 1
The nourishing the stomach cream that the present embodiment is provided is made up of plurality of raw materials.It is small that plurality of raw materials includes 20g honey, 0.8g alums, 1g
Soda, the 1g roots of kudzu vine, 0.5g Poria cocos and 1g Radix Glycyrrhizaes.
The preparation method for the nourishing the stomach cream that the present embodiment is provided：
Mix and mixed again with 100g water after the 1g roots of kudzu vine, 0.5g Poria cocos and 1g Radix Glycyrrhizaes are crushed respectively, and at 75 DEG C
At a temperature of decoct 2 hours.Decoct 2 times altogether.By decoct twice obtain decoct after juice is mixed and concentrated, concentration
Multiple is decoct juice total amount 1/4.
Under conditions of temperature is 40 DEG C, 0.8g alums are dissolved in after water after being mixed with above-mentioned concentrate, continued
Mixed with 20g honey.Then sodium bicarbonate is added in batches, 0.025g is added every time, then by the liquid on upper strata as bubble turns
Move to another storage container.And continue the supernatant liquid in container to mix, until each raw material has been transferred in reaction vessel
Entirely, the bubble and in storage container is wholly absent rear natural cooling.The time of whole heating process is 2 hours.
Embodiment 2
The nourishing the stomach cream that the present embodiment is provided is made up of plurality of raw materials.Plurality of raw materials includes 15g honey, 0.6g alums, 1.5g
Sodium bicarbonate, the 1.2g roots of kudzu vine, 1 Poria cocos, 0.8g Radix Glycyrrhizaes and 1g ginsengs.
The preparation method for the nourishing the stomach cream that the present embodiment is provided：
Mixed again with 110g water after the 1.2g roots of kudzu vine, 1 Poria cocos, 0.8g Radix Glycyrrhizaes and 1g ginsengs are crushed respectively, and 80
Decoct 2.5 hours, decoct 3 times respectively at a temperature of DEG C.And by decoct obtain decoct after juice is mixed and concentrated, it is dense
The multiple of degree is decoct juice total amount 1/5.
Under conditions of temperature is 60 DEG C, 0.6g alums are dissolved in after water after being mixed with above-mentioned concentrate, continued
Mixed with 15g honey.Then sodium bicarbonate is added in batches, 0.03g is added every time, then by the liquid on upper strata as bubble is shifted
To another storage container.And continue the supernatant liquid in container to mix, until each raw material is transferred completely in reaction vessel,
And the bubble in storage container is wholly absent rear natural cooling.The time of whole heating process is 1 hour.
Embodiment 3
The nourishing the stomach cream that the present embodiment is provided is made up of plurality of raw materials.Plurality of raw materials includes 25g honey, 0.7g alums, 0.8g
Sodium bicarbonate, the 2g roots of kudzu vine, 1.2 Poria cocos, 0.9g Radix Glycyrrhizaes, 0.8g ginsengs and 1.2g dandelions.
The preparation method for the nourishing the stomach cream that the present embodiment is provided：
Remixed after the 2g roots of kudzu vine, 1.2 Poria cocos, 0.9g Radix Glycyrrhizaes, 0.8g ginsengs and 1.2g dandelions are crushed respectively with
120g water is mixed, and is decocted 3 hours at a temperature of 60 DEG C, is decocted 3 times respectively.And the juice that decocts for obtaining decoction is blended in one
Concentrated after rising, the multiple of concentration is decoct juice total amount 1/6.
Under conditions of temperature is 50 DEG C, 0.7g alums are dissolved in after water after being mixed with above-mentioned concentrate, continued
Mixed with 25g honey.Then sodium bicarbonate is added in batches, 0.015g is added every time, then by the liquid on upper strata as bubble turns
Move to another storage container.And continue the supernatant liquid in container to mix, until each raw material has been transferred in reaction vessel
Entirely, the bubble and in storage container is wholly absent rear natural cooling.The time of whole heating process is 3 hours.
Embodiment 4
The nourishing the stomach cream that the present embodiment is provided is made up of plurality of raw materials.Plurality of raw materials includes 17g honey, 0.5g alums, 1.2g
Sodium bicarbonate, the 1.5g roots of kudzu vine, 1.5 Poria cocos, 1.2g Radix Glycyrrhizaes, 1.2g ginsengs and 0.8g dandelions.
The preparation method for the nourishing the stomach cream that the present embodiment is provided：
Remixed after the 1.5g roots of kudzu vine, 1.5 Poria cocos, 1.2g Radix Glycyrrhizaes, 1.2g ginsengs and 0.8g dandelions are crushed respectively
Mix, and decocted 2.5 hours at a temperature of 65 DEG C with 115g water, decocted 2 times respectively.And mix the juice that decocts that decoction is obtained
Concentrated afterwards together, the multiple of concentration is decoct juice total amount 1/4.
Under conditions of temperature is 55 DEG C, 0.5g alums are dissolved in after water after being mixed with above-mentioned concentrate, continued
Mixed with 17g honey.Then sodium bicarbonate is added in batches, 0.02g is added every time, then by the liquid on upper strata as bubble is shifted
To another storage container.And continue the supernatant liquid in container to mix, until each raw material is transferred completely in reaction vessel,
And the bubble in storage container is wholly absent rear natural cooling.The time of whole heating process is 2.5 hours.
Embodiment 5
The nourishing the stomach cream that the present embodiment is provided is made up of plurality of raw materials.Plurality of raw materials includes 22g honey, 0.65g alums, 0.9g
Sodium bicarbonate, the 1.8g roots of kudzu vine, 0.7 Poria cocos, 1.1g Radix Glycyrrhizaes, 0.9g ginsengs and 1g dandelions.
The preparation method for the nourishing the stomach cream that the present embodiment is provided：
Remixed after the 1.8g roots of kudzu vine, 0.7 Poria cocos, 1.1g Radix Glycyrrhizaes, 0.9g ginsengs and 1g dandelions are crushed respectively with
105g water is mixed, and is decocted 3 hours at a temperature of 70 DEG C, is decocted 2 times respectively.And the juice that decocts for obtaining decoction is blended in one
Concentrated after rising, the multiple of concentration is decoct juice total amount 1/6.
Under conditions of temperature is 45 DEG C, 0.65g alums are dissolved in after water after being mixed with above-mentioned concentrate, continued
Mixed with 22g honey.Then sodium bicarbonate is added in batches, 0.03g is added every time, then by the liquid on upper strata as bubble is shifted
To another storage container.And continue the supernatant liquid in container to mix, until each raw material is transferred completely in reaction vessel,
And the bubble in storage container is wholly absent rear natural cooling.The time of whole heating process is 1.5 hours.
Experimental example 1
Helicobacter pylori extracorporeal bacteria inhibitor test is carried out to embodiment 1- embodiments 5 using test tube double dilution method.
Culture medium：Brucella broth：According to newly organized bacteriologic test culture handbook [the newly organized bacteriologic test of Du Pinghua, Lv Wen and
With culture handbook [M] Qingdao；Ocean university press, 1994,106] culture medium is made.Added after Skirrow medium sterilizations
TMP antibacterial mixed liquors：TMP (trimethoprim (TMP)) 5mg, vancomycin 10mg, polymyxins μ and cephalosporin 15mg.
Helicobacter pylori Isolation and Culture：Mucosa tissue is taken uniformly to be applied to the double dish of the above-mentioned Skirrow being ready for
On, it is placed in 37 DEG C of micro- oxygen environments and (adds catalyst using Germany bio meerieux generdox, make into micro- oxygen environment 5%-
8%CO2, 33.6%H2O).Observation colony shape, feature, color, biochemical reaction after being incubated 48 hours, and quick urea is made simultaneously
Enzyme is tested.
It is prepared by bacterium solution：With 10% after helicobacter pylori of the above-mentioned separation by identification is increased into bacterium 48 hours with brucella broth
Glucose Liquid is diluted to 10-5(every milliliter of containing about 1000 bacterium).
It is prepared by decoction：Weigh after the nourishing the stomach cream 10g of embodiment 1- embodiments 5 and 50ml water mixed dissolutions, shift respectively
Into 100ml volumetric flasks, and constant volume (every milliliter of pastille 1g).Sterilizing 20 minutes, it is standby.
Method：Every group takes sterile test tube 13, and every addition brucella broth 1ml, the first pipe adds the decoction of embodiment
1ml is drawn after 1ml, mixing, second is added and manages, the 12nd pipe is diluted to method, 1ml is taken out from the 12nd pipe and is used as blank pair
According to each Guan Zhongjia bacterium solutions 10-40.1ml (about 1000 bacterium), is mixed, and result is observed after putting 37 DEG C of micro- oxygen environment cultures 48 hours.
Liquid muddiness shows there is bacteria growing；Liquid is clarified, and is still clarified after shaking up, asepsis growth.The concentration of asepsis growth is minimum medicine
Concentration.Each pipe for having no bacterial growth is taken into 1ml successively, Skirrow culture mediums is injected after adding double dish, shakes up, be placed in 37 DEG C
Micro- oxygen environment culture 72 hours, has seen whether that the medicine for the minimum dilution factor that the clump count on bacteria growing, flat board is less than 5 is dense
Spend for minimum bactericidal concentration.Concrete outcome is shown in Table 1.
The antibacterial result of table 1
By table 1, the nourishing the stomach cream of embodiment 1- embodiments 5 is 1 to helicobacter pylori MIC:64, MBC be 1:64,
MBC is 1:64 show that nourishing the stomach cream has good sterilization, bacteriostasis for helicobacter pylori.
Experimental example 2
40-50 Sui is selected, 300 patients with gastric disease are divided into 5 groups of patients, and every group is taken same amount of support in same time
Stomach cream；8 points of morning and at 21 points in evening eat 2 times respectively daily, each taking 5ml.Edible effect is filled in respectively at 28 days, 56 days
Really.
Wherein, the symptom such as Nausea and vomiting, sour regurgitation, glutted, pain, belch is eased be determined as effectively, by nausea,
At least one of the symptom such as vomiting, sour regurgitation, glutted, pain, belch symptom disappear be determined as it is effective, by Nausea and vomiting, sour regurgitation, full
The symptoms such as swollen, pain, belch, which disappear, is determined as recovery from illness.Concrete outcome is shown in Table 2.
The patients with gastric disease of table 2 improves situation
By table 2, the nourishing the stomach cream that embodiment of the present invention 1- embodiments 5 are provided has for stomach trouble good controls curative effect
Really.Wherein, it is all effective to take after 56 days, at least 35% patient's recovery from illness, and obvious effective rate is up to 55%.
In summary, each component of embodiment of the present invention 1-5 nourishing the stomach cream is the effect being mutually improved, honey can it is sterilized and
It is antibacterial, meanwhile, gastric acid secretion can be promoted normal.Alum and sodium bicarbonate are generated in aluminium hydroxide and stomach except that can react
Acid, alum also can sterilized, sodium bicarbonate also neutralize hydrochloric acid in gastric juice, honey can also promote liver toxin expelling, strengthen body immunity, and reduction is supported
The toxic and side effect of stomach cream, lifts the curative effect of nourishing the stomach cream.And the root of kudzu vine, Poria cocos and liquorice can also be alleviated and have a stomach upset, meanwhile, reduction
The toxic and side effect of other raw materials, and then the therapeutic effect of overall enhancing nourishing the stomach cream.And can be fast by the preparation method of the present invention
Speed prepares the nourishing the stomach cream with treatment stomach trouble.
Embodiments described above is a part of embodiment of the invention, rather than whole embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. a kind of nourishing the stomach cream, it is characterised in that the nourishing the stomach cream is made up of plurality of raw materials, in parts by weight, the plurality of raw materials
Including 15-25 parts of honey, 0.5-0.8 parts of alums, 0.8-1.5 parts of sodium bicarbonate, the 1-2 parts of roots of kudzu vine, 0.5-1.5 parts of Poria cocos and 0.8-
1.2 portions of Radix Glycyrrhizaes.
2. nourishing the stomach cream according to claim 1, it is characterised in that the plurality of raw materials also includes 0.8-1.2 parts of ginsengs.
3. nourishing the stomach cream according to claim 1, it is characterised in that the plurality of raw materials also includes 0.8-1.2 portions of dandelions.
4. nourishing the stomach cream according to claim 1, it is characterised in that the plurality of raw materials include the 18-22 parts of honey,
0.5-0.6 parts of alums, 1-1.2 parts of sodium bicarbonate, 1-1.5 parts of roots of kudzu vine, 0.8-1.2 parts of Poria cocos and 0.8-
1.2 parts of Radix Glycyrrhizaes.
5. a kind of method for preparing nourishing the stomach cream, it is characterised in that comprise the following steps：In parts by weight, by the 1-2 parts of roots of kudzu vine,
0.5-1.5 parts of Poria cocos and 0.8-1.2 portions of Radix Glycyrrhizaes are concentrated to give concentrate after decocting；
In a heated condition, after 0.5-0.8 parts of alums are mixed with water and the concentrate, continuation is mixed with 15-25 parts of honey,
0.8-1.5 parts of sodium bicarbonate are added in batches again to be well mixed.
6. it is according to claim 5 prepare nourishing the stomach cream method, it is characterised in that add in batches the sodium bicarbonate be by
The 0.015-0.03 parts of sodium bicarbonate are added to be stirred in the mixture of the alum, the concentrate and the honey after
Add the 0.015-0.03 parts of sodium bicarbonate after supernatant liquid and foam are scooped out into the mixture again.
7. the method according to claim 6 for preparing nourishing the stomach cream, it is characterised in that by the supernatant liquid and the foam
Continue to stir the supernatant liquid after being scooped out.
8. the method according to claim 5 for preparing nourishing the stomach cream, it is characterised in that concentration is by the root of kudzu vine, the Fu
The juice that decocts of Siberian cocklebur and the Radix Glycyrrhizae is concentrated into decoct juice 1/4-1/6 times.
9. the method according to claim 5 for preparing nourishing the stomach cream, it is characterised in that the alum, the concentrate, described
Cooled down after honey and the sodium bicarbonate are well mixed.
10. the method according to claim 5 for preparing nourishing the stomach cream, it is characterised in that the temperature of heating is 40-60 DEG C, plus
The hot time is 1-3 hours.
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| CN111632107A (en) * | 2020-05-11 | 2020-09-08 | 李易罡 | Medicinal and edible health-care particle and preparation method thereof |
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