CN106822720A - A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion - Google Patents

A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion Download PDF

Info

Publication number
CN106822720A
CN106822720A CN201710219420.2A CN201710219420A CN106822720A CN 106822720 A CN106822720 A CN 106822720A CN 201710219420 A CN201710219420 A CN 201710219420A CN 106822720 A CN106822720 A CN 106822720A
Authority
CN
China
Prior art keywords
parts
root
stem
radix
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710219420.2A
Other languages
Chinese (zh)
Inventor
孙晓风
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201710219420.2A priority Critical patent/CN106822720A/en
Publication of CN106822720A publication Critical patent/CN106822720A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion, belong to the field of Chinese medicines.The raw material of effective ingredient of the present invention is constituted:Henry woodbetony root, fern fiber crops, digua fig stem and leaf, date, hirsute gonostegia herb with root, the red sage root, saline cistanche, sophora flower, Chinese Fevervine Herb, Radix Codonopsis, fiveleaf akebia root, trifoliate orange, Semen sesami nigrum, the stem of noble dendrobium, Radix Glycyrrhizae, Flos Imperatae, the radix paeoniae rubrathe, Radix Triostei Pinnatifidi, dried orange peel, Medicated Leaven, Japanses beauty-berry grass, Rhizoma Sparganii, common perilla stem, coriander seed.The present invention is mutually fitted mutually auxiliary from the property of medicine of medicinal material, suited the remedy to the case for the cause of disease, in having the effect of strengthening the spleen and stomach, tonifying Qi and blood, promoting blood circulation and removing blood stasis, regulating qi-flowing for relieving pain, the promoting flow of qi and blood circulation, lower controlled atmosphere, promoting digestion and removing indigestion, clearing heat and promoting diuresis, relax bowel, nourishing Yin and promoting production of body fluid, good absorbing effect, it is evident in efficacy, have no toxic side effect and clinical adverse, it is higher to abdominal postoperative intestinal adhesion cure rate according to clinical verification.

Description

A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of instant particles as Chinese medicine and preparation side for treating postoperative intestinal adhesion Method.
Background technology
Intestinal adhesion is the common complication of abdominal postoperative.Intestinal adhesion is primarily due in art to intestinal tube and its mistake of mesentery Degree is pulled to stimulate, hemostasis does not form hemotoncus thoroughly, intestinal tube open-assembly time outside abdominal cavity is oversize, auxiliary material covers contact damage for a long time The factors such as serous coat, peritonaeum tear damage, bulk tissue ligation, abdominal cavity or incision of abdominal wall infection cause, and factors above causes belly, Organ poor arterial inflow in the abdomens such as intestinal tube nethike embrane, vasopermeability increases, and tissue fluid oozes out and increases, and has substantial amounts of fibrin deposition With coagulated fibre protein dissolution obstacle, cause Adhesion formation.Clinic with abdominal pain as cardinal symptom, with abdominal distension, constipation and The symptom such as not smooth is vented, some patient's stubbornnesses take place frequently, and serious caused intestinal obstruction, the new and old weight difference of the state of an illness is very big.At present Doctor trained in Western medicine has no specific short to this disease, and treatment method is relatively simple, takes the method performed the operation again to be treated more, but operation is controlled Treatment easily forms new intestinal adhesion, and therapeutic effect is not good enough, and great pain is brought to patient
Intestinal adhesion belongs to the categories such as the traditional Chinese medical science " intestines knot ", " abdominal distension ", " stomachache ", and the interpretation of the cause, onset and process of an illness is that abdominal operation causes injury of small vessels, hemostasis in abdomen, Disorder of qi, " not general rule bitterly ", so stomachache, abdominal distension, inhibited defecation;Hemostasis is accumulated and changes heat therefore bitter taste.The traditional Chinese medical science thinks that this is gas Blood is damaged, and qi depression to blood stasis, enteron aisle blockage of channel is caused.Therefore treatment should give qi-regulating promoting blood circulation and removing blood stasis, then hemostasis mechanism of qi leads to abdomen Pain is stopped, i.e., " no pain by smooth breath ", and internal organs is suitable to lead to, to be reduced to and so being treated with stagnation resolvation qi-regulating opinion, hemostasis is removed, internal organs gas Obtain general rule stomachache to stop, determined curative effect, stabilization, cure rate is high.The present invention is to summarize configuration through long-term clinical practice to form, with strong In spleen and stomach, tonifying Qi and blood, promoting blood circulation and removing blood stasis, regulating qi-flowing for relieving pain, the promoting flow of qi and blood circulation, lower controlled atmosphere, promoting digestion and removing indigestion, clearing heat and promoting diuresis, ease constipation lead to Just, the effect of nourishing Yin and promoting production of body fluid, can tonifying Qi and blood nourishing Yin and promoting production of body fluid to effect a permanent cure, the logical lower dissipate-swelling of stagnation resolvation qi-regulating to take stopgap measures, so as to reach Adhesion release, internal organs gas are unimpeded, and illness is cured the disease and ask source to treat both principal and secondary aspect of disease from disappearing, and medicine disease is consistent, and good absorbing effect is evident in efficacy, nontoxic Side effect and clinical adverse are higher to abdominal postoperative intestinal adhesion cure rate according to clinical verification.
The content of the invention
The invention provides a kind of instant particles as Chinese medicine for treating abdominal postoperative intestinal adhesion, with strengthening the spleen and stomach, tonifying Qi and blood, In promoting blood circulation and removing blood stasis, regulating qi-flowing for relieving pain, the promoting flow of qi and blood circulation, lower controlled atmosphere, promoting digestion and removing indigestion, clearing heat and promoting diuresis, relax bowel, the work(of nourishing Yin and promoting production of body fluid Effect, cures the disease and asks source to treat both principal and secondary aspect of disease, and has good curative effect to abdominal postoperative intestinal adhesion.
To achieve the above object, technical scheme is implemented as follows:
A kind of instant particles as Chinese medicine for treating abdominal postoperative intestinal adhesion, is made the raw material composition and weight portion of the effective ingredient Number is:
15~30 parts of henry woodbetony root, 15~30 parts of fern fiber crops, 10~30 parts of digua fig stem and leaf, 10~25 parts of date,
10~25 parts of hirsute gonostegia herb with root, 10~20 parts of the red sage root, 10~15 parts of saline cistanche, 9~15 parts of sophora flower,
9~15 parts of Chinese Fevervine Herb, 9~15 parts of Radix Codonopsis, 6~15 parts of fiveleaf akebia root, 6~15 parts of trifoliate orange,
6~15 parts of Semen sesami nigrum, 6~12 parts of the stem of noble dendrobium, 6~12 parts of Radix Glycyrrhizae, 6~12 parts of Flos Imperatae,
6~10 parts of the radix paeoniae rubrathe, 6~10 parts of Radix Triostei Pinnatifidi, 5~10 parts of dried orange peel, 4~9 parts of Medicated Leaven,
4~9 parts of Japanses beauty-berry grass, 3~9 parts of Rhizoma Sparganii, 3~9 parts of common perilla stem, 1~6 part of coriander seed.
Be made the effective ingredient raw material composition and parts by weight be:
25 parts of henry woodbetony root, fern fiber crops 25 parts, 20 parts of digua fig stem and leaf, 18 parts of date,
16 parts of hirsute gonostegia herb with root, 15 parts of the red sage root, 13 parts of saline cistanche, 13 parts of sophora flower,
12 parts of Chinese Fevervine Herb, 12 parts of Radix Codonopsis, 10 parts of fiveleaf akebia root, 10 parts of trifoliate orange,
10 parts of Semen sesami nigrum, 10 parts of the stem of noble dendrobium, 9 parts of Radix Glycyrrhizae, 9 parts of Flos Imperatae,
9 parts of the radix paeoniae rubrathe, 8 parts of Radix Triostei Pinnatifidi, 8 parts of dried orange peel, 7 parts of Medicated Leaven,
6 parts of Japanses beauty-berry grass, 6 parts of Rhizoma Sparganii, 5 parts of common perilla stem, 3 parts of coriander seed.
A kind of preparation method of the instant particles as Chinese medicine for treating abdominal postoperative intestinal adhesion, comprises the following steps that:
(1)By henry woodbetony root, fern fiber crops, digua fig stem and leaf, date, hirsute gonostegia herb with root, trifoliate orange, Semen sesami nigrum, the stem of noble dendrobium, Flos Imperatae, Radix Triostei Pinnatifidi, dried orange peel, Japanses beauty-berry grass, Rhizoma Sparganii, common perilla stem, coriander seed are cleaned after drying and are well mixed, and are put into container, and 6~8 times of addition in a reservoir is measured Water, heating is boiled 2~3 hours, and immersion liquid is taken after cooling;Adding 4~6 times of water of amount in the remaining dregs of a decoction, heating boils 1~ 2 hours, immersion liquid is taken after cooling;Merge gained immersion liquid twice, heat, it is the thick paste of relative density 1.15~1.25 to be concentrated by evaporation, It is standby;
(2)Danshen Tablets are taken, plus yellow rice wine is mixed thoroughly, vexed profit is put in pot to saturating, is fried with slow fire, and taking-up is cooled, and crushing is ground, and crosses 100 mesh Dusting cover, obtains fine powder, standby;
(3)Saline cistanche, Chinese Fevervine Herb, fiveleaf akebia root are put into container, 3~5 times of shao-hsing rice wine of amount are added, cooled after boiling, after Continuous immersion 3~5 hours, takes immersion liquid;2~4 times of shao-hsing rice wine of amount are added in the remaining dregs of a decoction, is cooled after boiling, continued Immersion 2~4 hours, takes immersion liquid;Merge gained immersion liquid twice, plus be concentrated by evaporation the thick paste for relative density 1.10~1.20, It is standby;
(4)Net sophora flower is taken, is put in iron pan, heated with slow fire, fried to buff, taking-up is cooled, and crushing is ground, cross 100 mesh dusting covers, Fine powder is obtained, it is standby;
(5)Wheat bran is placed in the pot of heating, to pot on when playing cigarette, add Radix Codonopsis piece, stir to buff, taking-up weeds out bran Skin, cools, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(6)Net licorice tablet is taken, cooked honey and a little boiling water is added, it is slightly vexed after mixing thoroughly, to put in frying container, slow fire is fried to depth Yellow, takes out when tack-free, cools, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(7)Radix paeoniae rubrathe piece is taken, plus yellow rice wine is mixed thoroughly, it is slightly vexed, after wine is sucked, put in preheating frying container, heated with slow fire, fry extremely Slightly yellow, taking-up dries in the air cool, weeds out chip, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(8)Medicated Leaven is taken, is cut into small pieces, fry sallow to surface with slow fire, taken out, cooled, crushing is ground, cross 100 mesh dusting covers, obtained Fine powder, it is standby;
(9)By step(1), step(3)The thick paste of gained, with step(2), step(4), step(5), step(6), step(7)、 Step(8)The fine powder of middle gained, plus be made particle after auxiliary material sucrose and dextrin are well mixed, dries, after whole grain, is packaged into every bag The instant particles as Chinese medicine of 12g.
The property of medicine of Chinese medicine used of the invention is as follows:
Henry woodbetony root:It is sweet;Slight bitter;Slightly warm in nature.Fill blood;Strengthening the bones and muscles;Strengthening the spleen and stomach.Cure mainly dizziness and tinnitus;Palpitation and short breath;Brothers' impotence It is soft;Arthralgia and myalgia;Bronchitis;Infantile indigestion with food retention;It is malnutritive.
Fern fiber crops:It is sweet;It is bitter;It is cold.Returns spleen;Stomach.Fill blood, strengthening the spleen and stomach promotes the production of body fluid to quench thirst, dampness removing.For anaemia after being ill, battalion Support bad, insufficiency of the spleen diarrhoea, arthralgia pain due to rheumatism.《Often use Chinese herbal medicine in Tibet》:" invigorating spleen and reinforcing stomach, promotes the production of body fluid to quench thirst, blood-enrich, controls insufficiency of the spleen Diarrhoea, anaemia, malnutritive after being ill." modern study is proved:Two kind compositions of the fern fiber crops containing contraction and relaxing smooth muscle, to smooth Flesh has certain influence, and has cardiotonic.
Digua fig stem and leaf:Bitter;It is cold in nature.Clearing heat and promoting diuresis, promoting blood circulation and removing obstruction in channels, removing toxicity for detumescence.Cure mainly cough with lung heat;Dysentery;Oedema;It is yellow Subcutaneous ulcer;Children's indigestion;Rheumatalgia pain;Amenorrhea;Under band;Traumatic injury;Hemorrhoid hemorrhage;Nameless sores or boils.《Traditional Chinese Medicine in Sichuan will》:Profit Urine, disappears damp and hot yellow swollen, and the logical moon is closed, only leukorrhea;Control hemorrhoid hemorrhage and swelling and aching of gum.
Date:It is sweet;Temperature.Returns spleen;Stomach.Tonifying spleen and stomach;Replenishing qi and blood;Tranquilizing mind;Battalion is adjusted to defend;And the property of medicine.Cure mainly taste empty It is weak;Insufficiency of vital energy and blood;Anorexia and loose stool;Lassitude hypodynamia;Palpitation and insomnia;Hysteria of womam;It is disharmony between ying and wei.《This warp》:Main trusted subordinate's perverse trend, peace In support spleen, help 12 warps.Flat stomach gas, lead to nine orifices, mend few gas, few body fluid, not enough in body, frightened, heaviness of limbs, and hundred medicines.
Hirsute gonostegia herb with root:It is sweet;Slight bitter;It is cool in nature.It is clearing heat and detoxicating;Invigorating the spleen disperse accumulations;It is inducing diuresis and reducing edema;Dissipate stasis of blood hemostasis.Cure mainly acute mastitis;It is swollen Poison;Dysentery;Indigestion;Dyspeptic abdominalgia;Glucoside is accumulated;Under band;Oedema;Difficult urination;Dysmenorrhoea;Traumatic injury;Hemoptysis;Spit blood;Outward Hinder bleeding.《Conventional single medicine compilation among the people》Increasing blood, strengthening the spleen and stomach, Gu middle blood-nourishing.For oral administration the controlling of fricassee has a weak heart.
The red sage root:Bitter;Cold nature;It is nontoxic.Enter the heart;Liver Channel.Promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle. For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative. 《This warp》Carry:" main trusted subordinate's perverse trend, borborygmus are faint such as to leak water, fever and chills accumulation;Broken disease removes lump in the abdomen, only dysphoria, QI invigorating." modern medicine grinds Study carefully confirmation, the red sage root has anti-inflammatory analgetic, coronary artery dilator, improves myocardial ischemia situation, hypotensive, hypoglycemic, reducing blood lipid, guarantor The effect of reparation with the regeneration of liver, antibacterial and promotion organization, the red sage root also has anti-platelet aggregation, reduces blood viscosity and regulation The function of inside and outside blood coagulation system.
Saline cistanche:It is sweet;It is salty;It is warm in nature.Return kidney;Large intestine channel.Kidney-replenishing;Benefiting essence-blood;Ease constipation road.Cure mainly decline of kidney-YANG;Waist Pain flaccidity of lower limbs.《This warp》Carry:" main general debility, bowl spares, except fever and chills bitterly, support the five internal organs, Qiang Yin, strengthening the essence gas in stem.”《Collected statements on the herbal foundation》 Carry:" temperature is mended without high without heat, is warmed up without dry, sliding without letting out, therefore has calm name." modern medicine study confirmation, saline cistanche Immune Function can be improved, enterocinesia can be strengthened, play the role of to improve myenteron motor function, made with defecation is promoted With.
Sophora flower:Bitter;Cold nature.Enter liver;Lung;The heart;Large intestine channel.Cooling blood and hemostasis;Clear liver and improve vision.Cure mainly hematochezia;Hemorrhoid Blood under sore;Bloody flux;Hematuria;Blood strangury;Uterine bleeding;Spit blood;Bleeding from five sense organs or subcutaneous tissue;Liver heat headache;Red eye, swell pain;Carbuncle swells sore.《Book on Chinese herbal medicine is just》Carry: " cool large intestine kills infantile malnutrition due to digestive disturbances or intestinalparasites worm.Skin sore is controlled, the erosion of vulva is wet to itch, anal fistula, solution red bayberry dislikes sore, chancre volt poison." modern medicine study card Real, sophora flower contains rutin(That is rutin sophorin, Rytub), Quercetin(Quercetin), tannin, sophoradiol(sophoradiol), dimension The materials such as raw element A, with anti-inflammatory, antiviral, spasmolysis, antiulcer, step-down, reducing blood lipid effect, coronary vasodilator can be expanded, improvement Myocardial circulation, improves the function of capillary, keeps the normal resistance of capillary, reduces vasopermeability, prevents because of hair Thin fragility of blood vessels is excessive, the too high bleeding for causing of permeability, hypertension, diabetes, and clothes can prevent bleeding.
Chinese Fevervine Herb:Sweet acid;It is mild-natured.The thoughts of returning home;Liver;Spleen;Kidney channel.Dispelling wind and eliminating dampness;Promoting digestion and removing indigestion;Removing toxicity for detumescence;Promoting blood circulation stops Bitterly.Cure mainly and control arthralgia pain due to rheumatism;Dyspeptic abdominal distention;Infantile malnutrition;Diarrhoea;Dysentery;Heatstroke;Jaundice;Hepatitis;Hepatosplenomegaly;Cough;Scrofula Scrofula;Acute appendicitis;Nameless sores or boils;Pin is wet swollen rotten;Burn and scald;Eczema;Dermatitis;Traumatic injury;Flood dragon scorpion stings snake.《Chongqing herbal medicine》:Invigorating the spleen Dehumidifying, QI invigorating qi-restoratives.It is usually used in children thin and weak, the weak deficiency of vital energy of spleen, dyspepsia infantile malnutrition due to digestive disturbances or intestinalparasites, and adult's deficiency of vital energy edema, tympanites, tinnitus, diarrhoea, The enuresis, women weakness leukorrhea, does disease.And weak internal lesion caused by overexertion, empty dysentery, sub- scrofula of itching due to deficiency of vital energy unhealed.
Radix Codonopsis:It is sweet;It is mild-natured.Returns spleen;Lung channel.Strengthening the spleen and tonifying the lung;Nourishing generate fluid.Cure mainly weakness of the spleen and the stomach;Anorexia and loose stool;Four limbs It is weak;The deficiency syndrome of the lung is breathed with cough;Shortness of breath spontaneous perspiration;The all cards of qi-blood deficiency.《Moral is with book on Chinese herbal medicine》Carry:" clearing lung-heat gold, tonifying primordial Qi opens sound, helps muscle Power." modern medicine study confirmation, Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function, to excited and two kinds of suppression Nerve process all has an impact, and can raise red blood cell, hemoglobin, granulophilocyte, also anti-aging and anti-oxidant, anti-spoke The effect penetrate, being depressured.
Fiveleaf akebia root:Bitter;It is mild-natured;Return liver;Kidney channel.Dispelling wind and removing obstruction in the meridians;Inducing diuresis for removing edema;The promoting flow of qi and blood circulation;Filling liver kidney;Strengthening the bones and muscles. Cure mainly arthralgia pain due to rheumatism;Traumatic injury;Amenorrhea;Hernia;Testiclar gall;It is vexed that gastral cavity abdomen is swollen;Difficult urination;Under band;Worm snake bite.《Zhejiang River conventional herbal medicine among the people》:Wind-expelling pain-stopping, the promoting flow of qi and blood circulation, diuresis removing toxic substances.
Trifoliate orange:Taste is pungent;It is bitter;It is warm in nature.Return liver;Stomach.Soothing liver and harmonizing stomach;Regulating qi-flowing for relieving pain;Disperse accumulationsization is stagnant.Cure mainly fullness in chest and hypochondrium; Abdominal distention;Breast lumps;Hernia pain;Testiclar gall;Traumatic injury;Dyspepsia;Constipation;The prolapse of uterus.《Often use medium-height grass in Shanghai Medicine》:Sharp gas, stomach invigorating, defaecation.Control stomach turgor, indigestion, constipation, the prolapse of uterus, tuberculosis of breast.
Semen sesami nigrum:It is sweet;It is mild-natured.Return liver;Spleen;Kidney channel.Tonify the liver and kidney;Blood-nourishing strengthening the essence;Relax bowel.For dizzy eye Flower, Hiccough and deaf, poliosis, post disease alopecia, dry constipation of intestines.Modern medicine study is proved:Semen sesami nigrum have hypoglycemic effect, Promote adrenal gland effect, antiinflammatory action and have certain effect to angiocarpy.
The stem of noble dendrobium:It is sweet;Cold nature.Return stomach;Lung;Kidney channel.Promote the production of body fluid beneficial stomach;Nourishing Yin and clearing heat;Moistening lung kidney-nourishing;The strong waist of improving eyesight.It is main Control consumption of body fluid caused by febrile disease;Dry polydipsia;Deficiency of stomach-Yin;Stomachache is retched;Dryness of the lung dry cough;Abnormal heat is not moved back;Impairment of yin mesh cicada;Waist and knee is weak. 《Book on Chinese herbal medicine is just》Carry:" stem of noble dendrobium strengthening the essence is cloudy by force, strengthens muscle qi-restoratives, is good for pin knee, drives cold numbness, but palpitates with fear, will of feeling relieved, and has the wonderful of calm decomposition, Therefore can anneal, yin-nourishing, relieving restlessness, gas under clearing lung-heat, hot sweat of also only quenching one's thirst." modern medicine study confirms that the stem of noble dendrobium can significantly increase macrophage The phagocytosis of cell, can suppress the immune of cortisone or caused by cyclophosphamide, have significant Immunestimulatory effect, to ring phosphinylidyne Leucocyte caused by amine declines protective effect, and can significantly improve the activity of Nasopharyngeal Carcinoma Patients NK cells, can promote saliva, stomach Liquid, intestinal fluid secretion, can expand capilary, increase blood flow, strengthen myocardial contractive power, in addition with effects such as antipyretic, analgesias.
Radix Glycyrrhizae:It is sweet;It is mild-natured.The thoughts of returning home;Lung;Spleen;Stomach.Invigorate the spleen and benefit qi;It is clearing heat and detoxicating;Expelling phlegm and arresting coughing;Relieving spasm to stop pain;Adjust With all medicines.Cure mainly weakness of the spleen and the stomach;Lassitude hypodynamia;Palpitation;Coughing with a lot of sputum;Gastral cavity abdomen four limbs contraction;Carbuncle sore tumefacting virus;Alleviate Drug toxicity.《Compendium of Materia Medica》Carry:" Radix Glycyrrhizae is monarch in all medicines.72 kinds of mammary calculus poison are controlled, draft is malicious by every means for solution 1,002, adjusts It is active with from medicine." modern medicine study confirms that Radix Glycyrrhizae has a stronger detoxication, also antiulcer, anti-inflammatory, antispastic antibechic, Lowering blood pressure and blood fat, antitumaous effect, are widely used in treatment sphagitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis Etc. disease, additionally acted on anti-gastric-ulcer, gastritis.
Flos Imperatae:It is sweet;It is warm in nature.Enter lung;Liver two passes through.Promoting blood circulation and hemostasis;Dispersing blood stasis is relieved pain;Hemostasis is cured the wound.Cure mainly haematemesis;Nosebleed Blood;Knife wound.《Tang materia medica》Carry:" main bleeding from five sense organs or subcutaneous tissue, spits blood, and processs Chuan , An knife arrow sores, stops blooding and pain." modern medicine study confirmation, cogongrass Flower can improve vascular wall function, and enhancing capillary reduces vasopermeability to the resistance damaged, when reducing bleeding, blood coagulation Between.
The radix paeoniae rubrathe:Bitter;It is slightly cold.Return liver warp.Clearing heat and cooling blood;Promoting blood circulation.Cure mainly febrile virulent maculae;Hematemesis and epistaxis;Under intestines wind Blood;Red eye, swell pain;Carbuncle swells sore;Amenorrhoea;Dysmenorrhoea;Collapse band stranguria with turbid discharge;The stagnant hypochondriac pain of the stasis of blood;Hernia lump in the abdomen is gathered;Injury from falling down.《Legendary god of farming's book on Chinese herbal medicine Through》Carry:" bitter is put down, main perverse trend stomachache, except blood-arthralgia, broken hard product fever and chills hernia lump in the abdomen, analgesic, raw Chuan Gu." modern medicine study confirmation, The radix paeoniae rubrathe has anti-thrombosis function, antiplatelet aggregative activity, reducing blood lipid and anti arteriosclerosis effect, and to cardiovascular system There is certain influence, its water-alcohol extraction has significant sedation and analgesic effect, can slightly improve the acidity of gastric juice, can be used for Improve appetite, digestive function and some neuropathies.
Radix Triostei Pinnatifidi:Bitter;It is mild-natured.Dispelling wind and eliminating dampness;The promoting flow of qi and blood circulation;Help digestion.Cure mainly lumbago, skelalgia of rheumatism;Internal lesion caused by overexertion;Traumatic injury; Irregular menstruation;Dyspepsia.
Dried orange peel:Taste is pungent;It is sweet;It is cold in nature.Enter spleen;Stomach.Lower gas;In tune;Resolving sputum;Sober up.Cure mainly feeding desorder;Upper gas is tired of It is full;Get sick from drinking too much wine thirsty.《Japan hanako materia medica》Carry:" skin is processed and makees soup, can relieving alcoholism and wine it is thirsty, the multiple person of typhoid fever diet labor, dense pan-fried juice clothes.” Medicine clinical research shows that the aurantiamarin contained by dried orange peel can suppress gastric ulcer, reduces capillary permeability, with adjustment stomach Function and antiinflammatory action, its volatile oil have eliminating the phlegm, relieving asthma, promote digestive juice secretion and exclude the effect such as enteral pneumatosis, this There is coronary artery dilator outward, reduce blood pressure and cholagogic etc. is acted on.
Medicated Leaven:It is sweet;It is pungent;It is warm in nature;It is nontoxic.Enter spleen;Stomach.Strengthening the spleen and stomach;Promoting digestion and removing indigestion;Cure mainly retention of food and drink;Disappear Change bad;Abdominal fullness and distention;Poor appetite;Vomiting dysentery.《Book on Chinese herbal medicine is just》Carry:" sweet gas is put down, and stir-bake to yellowish is used as medicine, kind to help middle scorched earth dirty, Invigorating the spleen warm stomach, helped digestion lower gas, changes in stagnant tune, and , Po Disorder lumps in the abdomen, transporting and transforming nutrients from foodstuff, except the vomiting of cholera turgor are accumulated by phlegm.Its gas is rotten, therefore energy Except damp and hot, its property is puckery, therefore antidiarrheal dysentery again.Woman's movement of the foetus is treated because stagnant, children's abdomen heavily fortified point is controlled because of product." modern medicine study confirmation, six god Bent saccharomycete containing volume and B family vitamin, can improve a poor appetite, and normal stool function be maintained, while ore class medicine can also be helped Digest and assimilate.
Japanses beauty-berry grass:Bitter;It is puckery;It is cool in nature;It is flat.Return liver;Spleen;Stomach.Dissipate stasis of blood hemostasis;Swelling and pain relieving.For spitting blood;Spitting of blood; Bleeding from five sense organs or subcutaneous tissue;Have blood in stool;External curing traumatism and bleeding;Treating swelling and pain by traumatic injury;Treating rheumatic ostealgia.《Bencao Shiyi》Carry:" all poisonous substances of solution, ulcer, larynx Numbness, poison is swollen, and lower fistula, snake a poisonous snake mentioned in ancient books is bugbite, mad dog poison, and liquor takes;Also liquor washes sore swells, except blood skin long." modern medicine study card Real, Japanses beauty-berry grass contains the hemostatic compositions of flavonoids condensed tannin, increases small blood plate quantity, promotes blood vessel local contraction, with only Blood, the scattered stasis of blood, effect of anti-inflammatory, otch bleeding and postoperative hemorrhage when can be used to treat hemorrhage of gastrointestinal tract, surgical operation.
Rhizoma Sparganii:Taste is pungent;It is puckery;It is cool in nature.Enter liver;The spleen channel.Blood-breaking;Xiao Ji Zhi Tong.Cure mainly abdominal mass lump in the abdomen;The stagnant Amenorrhea of the stasis of blood; Dysmenorrhoea;Dyspepsia distending pain;Injuries from falls as well.《Japan hanako materia medica》Carry:" control married woman's blood vessels uncomfortable, pain in the chest and abdomen, fall tire, and disappear extravesated blood, mends Labor, lead to menstruation, control inflatable, disappear and flutter damage hemostasis, postpartum abdominal pain, blood fortune and place blood not under." modern medicine study confirmation, Rhizoma Sparganii can Strengthen intestinal contraction, have excitation to uterus, platelet aggregation, extension TFT, ablation thrombus can be suppressed, reduce WBV.
Common perilla stem:Taste is pungent;It is warm in nature.Return lung;The spleen channel.It is pleasant to help digestion;Analgesic;It is antiabortive.Food stagnation is cured mainly not change;Abdominal distention; Flu;Fetal irritability.《Traditional Chinese Medicine in Sichuan will》Carry:" lower gas chest wide, promoting the circulation of qi resolving sputum is helped digestion, and controls uncomfortable in chest, and dysphagia and regurgitation and the heart are twisted Bitterly." modern medicine study confirms that common perilla stem can promote gastric secretion, strengthens gastrointestinal peristalsis, promotes body sweating and heat resolving, in addition The also effect such as diuresis, eliminating the phlegm.
Coriander seed:Taste is pungent;Acid;It is mild-natured.Return lung;Stomach;Large intestine channel.Stomach invigorating disperse accumulations;Regulating qi-flowing for relieving pain;Promoting eruption is detoxified.Cure mainly food Product;Poor appetite;Chest diaphragm is full vexed;Abdominal distention;Evil of vomitting gastric disorder causing nausea;Rush down dysentery;Hematochezia;Prolapse of the anus;Hernia;Measles;Peppery rash is impermeable; The favus of the scalp;Headache;Toothache;Ear carbuncle.Modern medicine study is proved:The fruit of coriander seed drying and ripening is weak aromatic, typically may be used Shared with other medicines and make flavouring, can also promote stomach and intestine glandular secretion, moreover it is possible to promote choleresis, contained volatile oil has some Antifungic action.
The present invention compared with prior art, has the advantages that:
The present invention mutually fitted from the property of medicine of medicinal material it is mutually auxiliary, for trigger postoperative intestinal adhesion qi and blood is impaired, qi depression to blood stasis, enteron aisle are passed through The causes of disease such as network retardance are suited the remedy to the case, in having strengthening the spleen and stomach, tonifying Qi and blood, promoting blood circulation and removing blood stasis, regulating qi-flowing for relieving pain, the promoting flow of qi and blood circulation, a lower controlled atmosphere, Promoting digestion and removing indigestion, clearing heat and promoting diuresis, relax bowel, nourishing Yin and promoting production of body fluid the effect of, good absorbing effect is evident in efficacy, has no toxic side effect and faces Bed adverse reaction, it is higher to abdominal postoperative intestinal adhesion cure rate according to clinical verification.
Specific embodiment
The present invention is further elaborated with reference to specific embodiment.
Embodiment 1
The raw material of effective ingredient of the present invention is constituted and weight is:
15~30 parts of henry woodbetony root, 15~30 parts of fern fiber crops, 10~30 parts of digua fig stem and leaf, 10~25 parts of date,
10~25 parts of hirsute gonostegia herb with root, 10~20 parts of the red sage root, 10~15 parts of saline cistanche, 9~15 parts of sophora flower,
9~15 parts of Chinese Fevervine Herb, 9~15 parts of Radix Codonopsis, 6~15 parts of fiveleaf akebia root, 6~15 parts of trifoliate orange,
6~15 parts of Semen sesami nigrum, 6~12 parts of the stem of noble dendrobium, 6~12 parts of Radix Glycyrrhizae, 6~12 parts of Flos Imperatae,
6~10 parts of the radix paeoniae rubrathe, 6~10 parts of Radix Triostei Pinnatifidi, 5~10 parts of dried orange peel, 4~9 parts of Medicated Leaven,
4~9 parts of Japanses beauty-berry grass, 3~9 parts of Rhizoma Sparganii, 3~9 parts of common perilla stem, 1~6 part of coriander seed.
The processing step of process for preparing medicine of the present invention is:
(1)By henry woodbetony root, fern fiber crops, digua fig stem and leaf, date, hirsute gonostegia herb with root, trifoliate orange, Semen sesami nigrum, the stem of noble dendrobium, Flos Imperatae, Radix Triostei Pinnatifidi, dried orange peel, Japanses beauty-berry grass, Rhizoma Sparganii, common perilla stem, coriander seed are cleaned after drying and are well mixed, and are put into container, and 6~8 times of addition in a reservoir is measured Water, heating is boiled 2~3 hours, and immersion liquid is taken after cooling;Adding 4~6 times of water of amount in the remaining dregs of a decoction, heating boils 1~ 2 hours, immersion liquid is taken after cooling;Merge gained immersion liquid twice, heat, it is the thick paste of relative density 1.15~1.25 to be concentrated by evaporation, It is standby;
(2)Danshen Tablets are taken, plus yellow rice wine is mixed thoroughly, vexed profit is put in pot to saturating, is fried with slow fire, and taking-up is cooled, and crushing is ground, and crosses 100 mesh Dusting cover, obtains fine powder, standby;
(3)Saline cistanche, Chinese Fevervine Herb, fiveleaf akebia root are put into container, 3~5 times of shao-hsing rice wine of amount are added, cooled after boiling, after Continuous immersion 3~5 hours, takes immersion liquid;2~4 times of shao-hsing rice wine of amount are added in the remaining dregs of a decoction, is cooled after boiling, continued Immersion 2~4 hours, takes immersion liquid;Merge gained immersion liquid twice, plus be concentrated by evaporation the thick paste for relative density 1.10~1.20, It is standby;
(4)Net sophora flower is taken, is put in iron pan, heated with slow fire, fried to buff, taking-up is cooled, and crushing is ground, cross 100 mesh dusting covers, Fine powder is obtained, it is standby;
(5)Wheat bran is placed in the pot of heating, to pot on when playing cigarette, add Radix Codonopsis piece, stir to buff, taking-up weeds out bran Skin, cools, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(6)Net licorice tablet is taken, cooked honey and a little boiling water is added, it is slightly vexed after mixing thoroughly, to put in frying container, slow fire is fried to depth Yellow, takes out when tack-free, cools, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(7)Radix paeoniae rubrathe piece is taken, plus yellow rice wine is mixed thoroughly, it is slightly vexed, after wine is sucked, put in preheating frying container, heated with slow fire, fry extremely Slightly yellow, taking-up dries in the air cool, weeds out chip, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(8)Medicated Leaven is taken, is cut into small pieces, fry sallow to surface with slow fire, taken out, cooled, crushing is ground, cross 100 mesh dusting covers, obtained Fine powder, it is standby;
(9)By step(1), step(3)The thick paste of gained, with step(2), step(4), step(5), step(6), step(7)、 Step(8)The fine powder of middle gained, plus be made particle after auxiliary material sucrose and dextrin are well mixed, dries, after whole grain, is packaged into every bag The instant particles as Chinese medicine of 12g.
Usage and dosage:Orally, morning and evening sub-service that 2 times a day, is taken after mixing it with water for 1 hour before meals with boiling water, is within 10 days 1 course for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention is constituted and weight is:
25 parts of henry woodbetony root, fern fiber crops 25 parts, 20 parts of digua fig stem and leaf, 18 parts of date,
16 parts of hirsute gonostegia herb with root, 15 parts of the red sage root, 13 parts of saline cistanche, 13 parts of sophora flower,
12 parts of Chinese Fevervine Herb, 12 parts of Radix Codonopsis, 10 parts of fiveleaf akebia root, 10 parts of trifoliate orange,
10 parts of Semen sesami nigrum, 10 parts of the stem of noble dendrobium, 9 parts of Radix Glycyrrhizae, 9 parts of Flos Imperatae,
9 parts of the radix paeoniae rubrathe, 8 parts of Radix Triostei Pinnatifidi, 8 parts of dried orange peel, 7 parts of Medicated Leaven,
6 parts of Japanses beauty-berry grass, 6 parts of Rhizoma Sparganii, 5 parts of common perilla stem, 3 parts of coriander seed.
The process for preparing medicine processing step and usage and dosage of the present embodiment are same as Example 1.
Clinical data:
1st, case selection
Selection our hospital 45 postoperative intestinal adhesion patient clinicals observation, patient has abdominal operation medical history, have recurrent exerbation stomachache, The clinical symptoms such as abdominal distension, and it is diagnosed as postoperative intestinal adhesion through the surgery consultation of doctors and pneumoperitoneography postabdomen CT scan inspection.
2nd, therapeutic modality
Patient takes medicine of the present invention, and orally, morning and evening sub-service that 2 times a day is taken after mixing it with water for 1 hour before meals with boiling water, is within 14 days 1 treatment Journey.
3rd, efficacy determination
(1)Cure:After 1 course for the treatment of of medication, clinical symptoms all disappear, after drug withdrawal 3 months without recurrence;
(2)Take a turn for the better:Clinical symptoms substantially mitigate, or clinical symptoms disappear but have recurrence in 3 months substantially;
(3)It is invalid:Symptom is same to treat preceding no significant difference.
4th, treatment results
Through taking Chinese medicine of the present invention, follow-up carries out curative effect statistics in 3 months after drug withdrawal, as a result cures 38, takes a turn for the better 5, and invalid 2 Example, total effective rate 95.6%.
Model case is illustrated:
1st, Qin's ××, man, 37 years old.After the patient carried out operation for appendicitis before 2 months because of acute appendicitis, start abdomen occur Bitterly, abdominal distension is with the symptom such as Nausea and vomiting, when it is light when weight recurrent exerbation, later institute's interrogation is diagnosed as postoperative intestinal adhesion on inspection, After taking 1 course for the treatment of of Chinese medicine of the present invention, above-mentioned symptom is wholly absent, and follow-up has been fully recovered for 3 months without recurrence.
2nd, what ××, female, 26 years old.After patient is because of intestinal polyp resection operation, frequent appearance stomachache, flatulence, defecation be not smooth etc. Symptom, carrys out institute's interrogation, and postoperative intestinal adhesion is diagnosed as on inspection, and after taking 1 course for the treatment of of Chinese medicine of the present invention, above-mentioned symptom is complete Mistake is totally disappeared, follow-up has been fully recovered for 3 months without recurrence.
3rd, Lee's ××, man, 42 years old.After patient is because of knurl resection between peritonaeum skin, surgery recovery is fine, but after postoperative two weeks Start the symptoms such as stomachache distending pain, constipation occur, carry out institute's interrogation, postoperative intestinal adhesion is diagnosed as on inspection, it is of the present invention through taking After 1 course for the treatment of of Chinese medicine, above-mentioned symptom is wholly absent, and follow-up has been fully recovered for 3 months without recurrence.
Chinese medicine of the present invention is verified through long-term clinical practice, evident in efficacy, and Radix Codonopsis, henry woodbetony root in side, date, fern fiber crops can invigorating the spleen Mend stomach, tonifying Qi and blood;Fiveleaf akebia root, Radix Triostei Pinnatifidi can the promoting flow of qi and blood circulation, dredging collateral in side;Rhizoma Sparganii can blood-breaking, Xiao Ji Zhi Tong in side;Side The middle red sage root, the radix paeoniae rubrathe, hirsute gonostegia herb with root, digua fig stem and leaf, Flos Imperatae, Japanses beauty-berry grass, sophora flower can promoting blood circulation and removing blood stasis, clearing heat and promoting diuresis, removing toxicity for detumescence, the scattered stasis of bloods Hemostasis;Dried orange peel, common perilla stem can descend in controlled atmosphere, promoting the circulation of qi resolving sputum, help digestion in side;Trifoliate orange, coriander seed, Medicated Leaven, Chinese Fevervine Herb can in side Promoting digestion and removing indigestion, regulating qi-flowing for relieving pain;In side Semen sesami nigrum, saline cistanche can blood-nourishing strengthening the essence, relax bowel;The stem of noble dendrobium can nourishing Yin and clearing heat, life in side Tianjin benefit stomach;Radix Glycyrrhizae can coordinating the drug actions of a prescription in side;All medicines share in side, can tonifying Qi and blood nourishing Yin and promoting production of body fluid to effect a permanent cure, stagnation resolvation qi-regulating lead to Lower dissipate-swelling is unimpeded so as to reach adhesion release, internal organs gas to take stopgap measures, and from disappearing, another modern pharmacological research shows illness, cogongrass in side The Chinese medicines such as flower, sophora flower, dried orange peel can improve vascular wall function, and enhancing capillary reduces vasopermeability to the resistance damaged, Reduction is oozed out, and diminish inflammation oedema, and performance prevents and treats the effect of intestinal adhesion formation;Radix Codonopsis in side, coriander seed, Medicated Leaven, saline cistanche, The Chinese medicines such as the stem of noble dendrobium can strengthen gastrointestinal peristalsis, improve spleen and stomach function, promote gastric juice, intestinal fluid secretion, promote defecation, can effectively mitigate abdomen Swollen, promotion appetite, prevents and treats intestinal adhesion symptom;The Chinese medicine such as Rhizoma Sparganii, the red sage root, radix paeoniae rubrathe can improve blood circulation in side, be conducive to intestinal tube Oedema and inflammatory resolution, all medicines share are treated both principal and secondary aspect of disease, and medicine disease is consistent, and good absorbing effect is evident in efficacy, are had no toxic side effect and are faced Bed adverse reaction, it is higher to abdominal postoperative intestinal adhesion cure rate according to clinical verification.

Claims (3)

1. a kind of instant particles as Chinese medicine for treating abdominal postoperative intestinal adhesion, it is characterised in that:It is made the original of the effective ingredient Material composition and parts by weight are:
15~30 parts of henry woodbetony root, 15~30 parts of fern fiber crops, 10~30 parts of digua fig stem and leaf, 10~25 parts of date,
10~25 parts of hirsute gonostegia herb with root, 10~20 parts of the red sage root, 10~15 parts of saline cistanche, 9~15 parts of sophora flower,
9~15 parts of Chinese Fevervine Herb, 9~15 parts of Radix Codonopsis, 6~15 parts of fiveleaf akebia root, 6~15 parts of trifoliate orange,
6~15 parts of Semen sesami nigrum, 6~12 parts of the stem of noble dendrobium, 6~12 parts of Radix Glycyrrhizae, 6~12 parts of Flos Imperatae,
6~10 parts of the radix paeoniae rubrathe, 6~10 parts of Radix Triostei Pinnatifidi, 5~10 parts of dried orange peel, 4~9 parts of Medicated Leaven,
4~9 parts of Japanses beauty-berry grass, 3~9 parts of Rhizoma Sparganii, 3~9 parts of common perilla stem, 1~6 part of coriander seed.
2. a kind of instant particles as Chinese medicine for treating abdominal postoperative intestinal adhesion according to claim 1, it is characterised in that:It is made institute State effective ingredient raw material composition and parts by weight be:
25 parts of henry woodbetony root, fern fiber crops 25 parts, 20 parts of digua fig stem and leaf, 18 parts of date,
16 parts of hirsute gonostegia herb with root, 15 parts of the red sage root, 13 parts of saline cistanche, 13 parts of sophora flower,
12 parts of Chinese Fevervine Herb, 12 parts of Radix Codonopsis, 10 parts of fiveleaf akebia root, 10 parts of trifoliate orange,
10 parts of Semen sesami nigrum, 10 parts of the stem of noble dendrobium, 9 parts of Radix Glycyrrhizae, 9 parts of Flos Imperatae,
9 parts of the radix paeoniae rubrathe, 8 parts of Radix Triostei Pinnatifidi, 8 parts of dried orange peel, 7 parts of Medicated Leaven,
6 parts of Japanses beauty-berry grass, 6 parts of Rhizoma Sparganii, 5 parts of common perilla stem, 3 parts of coriander seed.
3. a kind of preparation method of the instant particles as Chinese medicine for treating abdominal postoperative intestinal adhesion, it is characterised in that:Including following technique step Suddenly:
(1)By henry woodbetony root, fern fiber crops, digua fig stem and leaf, date, hirsute gonostegia herb with root, trifoliate orange, Semen sesami nigrum, the stem of noble dendrobium, Flos Imperatae, Radix Triostei Pinnatifidi, dried orange peel, Japanses beauty-berry grass, Rhizoma Sparganii, common perilla stem, coriander seed are cleaned after drying and are well mixed, and are put into container, and 6~8 times of addition in a reservoir is measured Water, heating is boiled 2~3 hours, and immersion liquid is taken after cooling;Adding 4~6 times of water of amount in the remaining dregs of a decoction, heating boils 1~ 2 hours, immersion liquid is taken after cooling;Merge gained immersion liquid twice, heat, it is the thick paste of relative density 1.15~1.25 to be concentrated by evaporation, It is standby;
(2)Danshen Tablets are taken, plus yellow rice wine is mixed thoroughly, vexed profit is put in pot to saturating, is fried with slow fire, and taking-up is cooled, and crushing is ground, and crosses 100 mesh Dusting cover, obtains fine powder, standby;
(3)Saline cistanche, Chinese Fevervine Herb, fiveleaf akebia root are put into container, 3~5 times of shao-hsing rice wine of amount are added, cooled after boiling, after Continuous immersion 3~5 hours, takes immersion liquid;2~4 times of shao-hsing rice wine of amount are added in the remaining dregs of a decoction, is cooled after boiling, continued Immersion 2~4 hours, takes immersion liquid;Merge gained immersion liquid twice, plus be concentrated by evaporation the thick paste for relative density 1.10~1.20, It is standby;
(4)Net sophora flower is taken, is put in iron pan, heated with slow fire, fried to buff, taking-up is cooled, and crushing is ground, cross 100 mesh dusting covers, Fine powder is obtained, it is standby;
(5)Wheat bran is placed in the pot of heating, to pot on when playing cigarette, add Radix Codonopsis piece, stir to buff, taking-up weeds out bran Skin, cools, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(6)Net licorice tablet is taken, cooked honey and a little boiling water is added, it is slightly vexed after mixing thoroughly, to put in frying container, slow fire is fried to depth Yellow, takes out when tack-free, cools, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(7)Radix paeoniae rubrathe piece is taken, plus yellow rice wine is mixed thoroughly, it is slightly vexed, after wine is sucked, put in preheating frying container, heated with slow fire, fry extremely Slightly yellow, taking-up dries in the air cool, weeds out chip, and crushing is ground, and crosses 100 mesh dusting covers, obtains fine powder, standby;
(8)Medicated Leaven is taken, is cut into small pieces, fry sallow to surface with slow fire, taken out, cooled, crushing is ground, cross 100 mesh dusting covers, obtained Fine powder, it is standby;
(9)By step(1), step(3)The thick paste of gained, with step(2), step(4), step(5), step(6), step(7)、 Step(8)The fine powder of middle gained, plus be made particle after auxiliary material sucrose and dextrin are well mixed, dries, after whole grain, is packaged into every bag The instant particles as Chinese medicine of 12g.
CN201710219420.2A 2017-04-06 2017-04-06 A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion Withdrawn CN106822720A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710219420.2A CN106822720A (en) 2017-04-06 2017-04-06 A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710219420.2A CN106822720A (en) 2017-04-06 2017-04-06 A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion

Publications (1)

Publication Number Publication Date
CN106822720A true CN106822720A (en) 2017-06-13

Family

ID=59146520

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710219420.2A Withdrawn CN106822720A (en) 2017-04-06 2017-04-06 A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion

Country Status (1)

Country Link
CN (1) CN106822720A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110859A (en) * 2013-02-04 2013-05-22 槐业东 Traditional Chinese medicine composition for treating gastrointestinal function decline after abdominal operation and preparation method thereof
CN105749120A (en) * 2016-03-29 2016-07-13 赵文彬 Traditional Chinese medicine dissolved medicine for treating food-retention stomach obstruction type postpartum impairment by overeating and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110859A (en) * 2013-02-04 2013-05-22 槐业东 Traditional Chinese medicine composition for treating gastrointestinal function decline after abdominal operation and preparation method thereof
CN105749120A (en) * 2016-03-29 2016-07-13 赵文彬 Traditional Chinese medicine dissolved medicine for treating food-retention stomach obstruction type postpartum impairment by overeating and preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
沈开金: "四磨饮加减治疗术后肠粘连181例小结", 《浙江中医杂志》 *

Similar Documents

Publication Publication Date Title
CN105194565A (en) Traditional Chinese medicine pills for treatment of cardiac neurosis and preparation method thereof
CN104721548B (en) A kind of Chinese medicine foodcare washing lotion and preparation method thereof
CN103933405A (en) Pharmaceutical composition for treating qi-blood deficiency burn, and preparation method thereof
CN105497784A (en) Traditional Chinese medicine pill used for treating superficial thrombophlebitis and preparation method
CN104605372A (en) Nutritional herbal cuisine based on cancer radiotherapy patient and preparation method thereof
CN105687738A (en) Traditional Chinese medicine granules for treating intractable coughs and preparation method
CN105833172A (en) Traditional Chinese medicinal granules for treating asymptomatic myocardial ischemia and preparation method of traditional Chinese medicinal granules
CN105688002A (en) Traditional Chinese medicine granules for treating senile functional constipation and preparation method
CN105343604A (en) Traditional Chinese medicine pills for kidney yang deficiency type chronic pyelonephritis and preparation method thereof
CN106822720A (en) A kind of instant particles as Chinese medicine and preparation method for treating postoperative intestinal adhesion
CN104056224A (en) Medicine for treating habitual abortion and preparation method thereof
CN103877457A (en) Chinese medicinal preparation for treating renal calculus and preparation method thereof
CN103055271B (en) Medicament for treating chronic gastritis and preparation method of medicament
CN104857415A (en) Glutinous rice congee taken by patients with gastric carcinoma and producing method thereof
CN105596999A (en) Traditional Chinese medicine preparation for effectively treating hypertension
CN105169295A (en) Traditional Chinese medicine pills for treating puerperal uterine subinvolution and preparation method thereof
CN105287982A (en) Traditional Chinese medicine oral liquid for treating epilepsy and preparation method for traditional Chinese medicine oral liquid
CN105031335A (en) Medicament for nursing and treatment after microwave pulverization of gastric bezoars and its preparation method
CN103893496A (en) Traditional Chinese medicine preparation for treating stenocardia and preparation method thereof
CN108992531A (en) A kind of instant particles as Chinese medicine and preparation method thereof for treating the postoperative swelling of fracture of lower limb
CN109045269A (en) A kind of instant particles as Chinese medicine and preparation method thereof for treating postpartum anemic fainting
CN104056225A (en) Medicine for treating atrial fibrillation and preparation method thereof
CN103920122B (en) A kind of Chinese medicine preparation for treating gastroenteritis and preparation method
CN107320655A (en) A kind of instant particles as Chinese medicine and preparation method for treating spleen emptiness and wet sputum type menstrual vertigo
CN107137596A (en) A kind of instant particles as Chinese medicine and preparation method for treating amenorrhoea headache

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20170613

WW01 Invention patent application withdrawn after publication