CN103055271B - Medicament for treating chronic gastritis and preparation method of medicament - Google Patents
Medicament for treating chronic gastritis and preparation method of medicament Download PDFInfo
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Abstract
The invention discloses a medicament for treating chronic gastritis and a preparation method of the medicament, belonging to the field of the traditional Chinese medicine. The medicament comprises the following effective components in parts by weight: 50-65 parts of Chinese yam, 45-60 parts of bitter orange, 42-58 parts of prepared liquorice root, 38-54 parts of costustoot, 34-50 parts of cinnamon, 30-46 parts of baikal skullcap root, 28-44 parts of medicinal evodia fruit, 25-40 parts of common burreed rhizome, 22-36 parts of tangerine peel, 18-32 parts of nutgrass galingale rhizome, 15-28 parts of rhizoma pinellinae praeparata, 12-25 parts of radix bupleuri, 10-22 parts of radix paeoniae rubra, 8-18 parts of lily, 5-15 parts of rhizoma corydalis and 3-12 parts of turmeric root-tuber. According to the medicament, the formulation is reasonable; the medicine for relieving swelling and promoting tissue regeneration is taken as the monarch, the medicine for dispersing blood stasis and eliminating fullness is as the minister, and the medicine for clearing heat is as the assistant and the medicine for eliminating dampness is as the guide; by regulating vital energy, dredging collaterals, warming the middle and harmonizing stomach, the medicament is effective in activating the vitality of the body and has good absorption effect, obvious healing effect, no toxic or side effect and no clinical adverse reaction. Through clinical verifications, the medicament has relatively good treatment effect on non-atrophic chronic gastritis, atrophic chronic gastritis and special chronic gastritis.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine and preparation method that is used for the treatment of chronic gastritis.
Background technology
Chronic gastritis is the gastric mucosa chronic inflammatory disease being caused by the various causes of disease, according to histopathology change and pathological changes at the distribution position of stomach, in conjunction with the possible cause of disease, chronic gastritis can be divided into non-atrophic, atrophic and specific type three major types.Chronic non-atrophic gastritis refer to without Mucosal atrophy sexually revise, gastric mucosa layer is shown in the chronic gastritis take lymphocyte and plasma cell as main chronic inflammatory cell infiltration; Chronic atrophic gastritis refers to that the chronic gastritis that atrophic changes has occurred gastric mucosa; Specific type gastritis kind is a lot, due to different pathogeny, more rare clinically.
Helicobacter pylori be chronic gastritis topmost pathogenic because of, helicobacter pylori causes primary cellular defect by producing the material such as ammonia effect, secretion VacA A, its cytotoxin-associated gene protein can cause strong inflammatory reaction, its thalline cell wall also can be used as antigen induction immunoreation, causes the chronic inflammatory disease of gastric mucosa.Worldwide comparative study shows that the regional difference of atrophy and the raw incidence rate of intestinalization parallels with the difference of interzone incidence gastric cancer rate substantially, and generation and the development of this prompting chronic gastritis also relate to other factors outside helicobacter pylori infections.Up-to-date medical research finds, the morbidity of chronic gastritis and autoimmunity also have considerable relatedness, and autoimmunity gastritis, take the body of stomach mucosal atrophy that is rich in parietal cell as main, originally can have other autoimmune diseases as chronic lymphocytic thyroiditis, vitiligo etc.
The treatment of modern medicine to chronic gastritis, carries out eradication therapy mainly for helicobacter pylori, is specially adapted to, dysplasia person raw with gastric mucosal erosion, atrophy and intestinalization; The person that has indigestion symptom; There is gastric cancer family history person, conventionally adopt three radical cure schemes, to effecting a radical cure the tetrad scheme of the failed bismuth-containing selected agent.To the experiential therapy of functional dyspepsia; adopt and press down acid or antacid if ranitidine or omeprazole capsule, short digestive tract power reinforcing medicine are if many kinds of vertical ketone sheets, gastric mucosal protection medicine are as sucralfate chewable tablet etc.; these medicines, except symptomatic treatment effect, also have certain effect to gastric epithelial reparation and inflammation.But above-mentioned all medicines all exist certain side effect, can not remove chronic inflammatory disease old complaint by the mode of excitating organism activity, adjusting immunity of organisms.
Traditional Chinese medical theory is thought, it is due to stagnation of QI causing retention of food, stomach-QI being unable to descend normally that stomach characterizes, pathogenic fire derived from stagnation of liver-QI, pathogen usually intruding into collateral in protracted disease, Deficiency and coldness of spleen and stomach, qi depression to blood stasis, stagnation of liver-QI cold syndrome of the stomach, the reasons such as insufficiency of stomach blood stasis cause, reach the object of radical cure chronic gastritis, adjusting gastrointestinal function, should start with except full, heat clearing and damp drying, detumescence and promoting granulation, warming middle-JIAO for easing the stomach from regulating qi and dredging collateral, blood stasis dispelling, select Chinese prescription rationally to concoct and be used as medicine.
Summary of the invention
The invention provides a kind of medicine and preparation method that is used for the treatment of chronic gastritis, there is regulating qi and dredging collateral, blood stasis dispelling effect except full, heat clearing and damp drying, detumescence and promoting granulation, warming middle-JIAO for easing the stomach, cure the disease and ask source, the various chronic gastritis that a variety of causes is caused all has good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine for chronic gastritis, raw material composition and the parts by weight of making described effective ingredient are:
38～54 parts of 42～58 parts of Radix Aucklandiae of 45～60 parts of Radix Glycyrrhizae Preparatas of 50～65 parts of Fructus Aurantiis of Rhizoma Dioscoreae
25～40 parts of 28～44 parts of Rhizoma Sparganii of 30～46 parts of Fructus Evodiaes of 34～50 parts of Radix Scutellariaes of Cortex Cinnamomi
12～25 parts of 15～28 parts of Radix Bupleuri of 18～32 parts of Rhizoma Pinelliae Preparatum of 22～36 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
3～12 parts of 5～15 portions of Radix Curcumaes of 8～18 parts of Rhizoma Corydalis of 10～22 portions of Bulbus Liliies of Radix Paeoniae Rubra.
Raw material composition and the parts by weight of making described effective ingredient are:
42～50 parts of 45～55 parts of Radix Aucklandiae of 48～58 parts of Radix Glycyrrhizae Preparatas of 52～62 parts of Fructus Aurantiis of Rhizoma Dioscoreae
28～36 parts of 30～40 parts of Rhizoma Sparganii of 33～43 parts of Fructus Evodiaes of 36～46 parts of Radix Scutellariaes of Cortex Cinnamomi
15～23 parts of 18～26 parts of Radix Bupleuri of 21～29 parts of Rhizoma Pinelliae Preparatum of 25～33 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
5～9 parts of 8～12 portions of Radix Curcumaes of 10～16 parts of Rhizoma Corydalis of 12～18 portions of Bulbus Liliies of Radix Paeoniae Rubra.
Raw material composition and the parts by weight of making described effective ingredient are:
46 parts of 50 parts of Radix Aucklandiae of 53 parts of Radix Glycyrrhizae Preparatas of 57 parts of Fructus Aurantiis of Rhizoma Dioscoreae
32 parts of 35 parts of Rhizoma Sparganii of 38 parts of Fructus Evodiaes of 41 parts of Radix Scutellariaes of Cortex Cinnamomi
19 parts of 22 parts of Radix Bupleuri of 25 parts of Rhizoma Pinelliae Preparatum of 29 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
7 parts of 10 portions of Radix Curcumaes of 13 parts of Rhizoma Corydalis of 15 portions of Bulbus Liliies of Radix Paeoniae Rubra.
Be used for the treatment of a preparation method for the medicine of chronic gastritis, comprise following processing step:
(1) Rhizoma Dioscoreae is smash as pasty state, add after the water of same deal, elimination residue, mass is for subsequent use.
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use.
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to vinegar exhaustion, use slow fire fried dry, after pulverizing, grind into powder, cross 140 order fine powders, for subsequent use.
(4) Bulbus Lilii is mixed thoroughly with refined honey, fry and be slightly coke yellow to surface and when tack-free with slow fire, after taking out and cooling, grind into powder, cross 140 order fine powders, for subsequent use.
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Sparganii, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; In remaining medicinal residues, add again the water of four times of amounts, soak after 3～5 hours, get immersion; Merge twice gained immersion, heating evaporation, under 50 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use.
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soak 3～5 hours, get immersion; In remaining medicinal residues, add again the shao-hsing rice wine of doubling dose, boil rear continuation and soak 2～3 hours, get immersion; Merge twice gained immersion, heating evaporation, under simmer down to room temperature environment, the thick paste of relative density 1.15～1.20, for subsequent use.
(7) mass step (1) being made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and after stirring, quick-freezing becomes powder, is prepared as tablet product with modern science technique.
The property of medicine of the present invention's Chinese medicine used is as follows:
Rhizoma Dioscoreae: sweet in the mouth; Property is put down.Enter lung; Spleen; Kidney channel.Spleen reinforcing; Support lung; Reinforce the kidney; Benefit essence.Cure mainly diarrhea due to hypofunction of the spleen; Lack of appetite edema; Cough and asthma due to lung deficiency; Quench one's thirst; Seminal emission; Leukorrhagia; The frequent micturition of suffering from a deficiency of the kidney; Carbuncle is controlled in external; Scrofula." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, and controls weakness, treats five kinds of strain and seven kinds of impairment." modern medicine study confirms, Rhizoma Dioscoreae can reduce blood glucose, regulates body to non-specific irritant reaction, effectively resists the Immunosuppression effect of cyclophosphamide, stimulates intestinal motility, promotes that intestinal contents is emptying, in addition can also be aid digestion, antidiarrheal, eliminate the phlegm.
Fructus Aurantii: bitter in the mouth; Acid; Cold nature.Enter lung; Spleen; Liver; Stomach; Large intestine channel.The chest stuffiness relieving of regulating the flow of vital energy; The stagnant removing food stagnancy of row.Cure mainly septum pectorale feeling of fullness; Distending pain over the hypochondrium; Accumulation of food in the stomach and intes tine due to indigestion; Distension and fullness in the abdomen; Heavy after dysentery; Proctoptosis; Uterine prolapse." detailed outline " carries: " control thoracic obstruction feeling of fullness, take Fructus Aurantii Immaturus as key medicine, all sides control the inferior internal hemorrhoid with bleeding dysentery, the secret plug of large intestine, and tenesmus, take Fructus Aurantii as general, Fructus Aurantii Immaturus is not only controled the inferior again, and Fructus Aurantii is not only controlled height also." clinic study shows, Fructus Aurantii has the effect of significant resisting pathogenic microbes, suppresses allergy, also has in addition calmness, diuresis, excited uterus, heart tonifying, boosts, the effect such as function of gallbladder promoting.
Radix Glycyrrhizae Preparata: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, solution 1,002 draft poison by every means, is in harmonious proportion from medicine meritorious." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have in addition anti-gastric-ulcer, gastritis effect.
The Radix Aucklandiae: acrid in the mouth; Bitter; Cold in nature; Slightly poisonous.Enter lung; Stomach warp.Promoting the circulation of QI to relieve pain; Removing toxic substances and promoting subsidence of swelling; Suppressing the hyperactive liver blood pressure lowering.Cure mainly breast side of body epigastric pain; Colicky; Intestinal inflammation; Dysentery stomachache; Cough phlegm dyspnea; Snake bite and insect sting; Carbuncle furuncle; Eczema; Skin pruritus; Hypertension." book on Chinese herbal medicine meets former " carries: " control large intestine, control wind syndrome of head, pruritus, tinea alba." clinic study shows; Radix Aucklandiae preparation has certain hypotensive effect; Radix Aristolochiae total alkaloids has inhibitory action in various degree to staphylococcus aureus, bacillus pyocyaneus, escherichia coli and modification bacillus; can improve non-specific antibody; strengthen the activate the phagocytic capacity of peritoneal macrophage; the defensive enginery of enhancing body, also has in addition calm, emetic action.
Cortex Cinnamomi: acrid in the mouth; Bitter; Hot in nature.Enter kidney; Spleen; The heart; Liver Channel.Mend fire supporing yang; Let the fire back to its origin; Dispersing cold for relieving pain; Warming the meridian and promoting blood circulation.Mainly treating intolerance of cold cold extremities; The dyspnea with rapid and short breath of losing heart; Decline of the fire from the gate of life; Fire is Gui Yuan not; Flushed complexion cold foot; Dizziness and tinnitus; Dispute is rotten broken; Spleen-kidney vacuity cold; Coldness and pain in the epigastrium; Decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain." property of medicine opinion " carries: " cure mainly nine types of precordial pain, kill three worms, main removing blood stasis, the tonneau moon closes, and controls weak foot, and numbness, meciless except cough with dyspnea, stagnation of QI, is gathered around numbness, and only cold air in abdomen, unbearably painful." modern medicine study confirmation, Cortex Cinnamomi contains the compositions such as cinnamic aldehyde, cinnamyl acetate, acetoxyphenyl group the third cheese, has the effect of fragrant stomach invigorating, antipyretic-antalgic, anti-inflammation.
Radix Scutellariae: bitter in the mouth; Cold in nature.Return lung; Gallbladder; Spleen; Stomach; Large intestine; Small intestine meridian.Heat clearing and damp drying; Eliminating fire and detoxication; Blood pressure lowering.Cure mainly hygropyrexia, heat-damp in summer vomiting and nausea uncomfortable in chest; Damp and hot feeling of fullness; Dysentery; Jaundice; Cough due to lung-heat; Heat in blood is told nosebleed; Carbuncle sore tumefacting virus." herbal classic " carries: " main all hot jaundice, intestinal is out-of-the-way, lets out profit, relieve oedema or abdominal distension through diuresis or purgation, acute scleritis." modern medicine study confirms, Radix Scutellariae has significantly the effects such as antibacterial, antifungal, antiviral, antiinflammatory, antiallergic action, can reduce blood pressure, anticoagulant, anticoagulant, blood fat reducing, protects the liver in addition in addition, function of gallbladder promoting, antioxidation, anticancer function.
Fructus Evodiae: acrid in the mouth; Bitter; Hot in nature; Mild toxicity.Enter liver; Stomach; Spleen; Large intestine; Kidney channel.Dispersing cold for relieving pain; The soothing the liver therapeutic method to keep the adverse QI flowing downwards; Warming middle-JIAO dampness.Cure mainly coldness and pain in the epigastrium; Headache due to JUE YIN disorder; Colic; Beriberi swells and ache; Vomiting acid regurgitation; Cold-damp is had loose bowels.Compendium of Material Medica is carried: " dissipating depression of QIization is stagnant, controls acid regurgitation, the cloudy sputum headache of fainting, and insidious stomachache, hernia, dysentery, mouthpiece's mouth is choked." modern medicine study confirmation, Fructus Evodiae has town to tell, antidiarrheal, and antiulcer, suppresses stomach motion, and heart tonifying, rises blood pressure, and shock improves microcirculation, improves the effects such as immunologic function.
Rhizoma Sparganii: acrid in the mouth; Puckery; Cool in nature.Enter liver; Spleen channel.Removing blood stasis circulation of qi promoting; Removing food stagnancy pain relieving.Cure mainly lump in the abdomen mass in the abdomen; The stagnant amenorrhea of the stasis of blood; Dysmenorrhea; Food stagnation distending pain; Traumatic pain." Japan hanako materia medica " carries: " control married woman's blood vessels uncomfortable, cardiac and abdominal pain, the tire that falls, the stagnant blood that disappears, mends labor, logical menstruation, controls flatulence, disappear and flutter damage blood stasis, puerperal abdonimal pain, blood fortune stagnated blood not under." modern medicine study confirms, Rhizoma Sparganii can be strengthened intestinal tube and shrink, and there is to excitation in uterus, can anticoagulant, extend thrombus formation time, melt thrombosis, reduce whole blood viscosity.
Pericarpium Citri Reticulatae: acrid in the mouth; Sweet; Cold in nature.Enter spleen; Stomach warp.The therapeutic method to keep the adverse QI flowing downwards; In tune; Reduce phlegm; Relieving alcoholic intoxication.Cure mainly drinking and eating irregularly; Upper gas stuffy sensation with restlessness; Get sick from drinking too much wine thirsty." Japan hanako materia medica " carries: " skin is processed and is made soup, can alcoholic intoxication and wine thirsty, typhoid fever diet recurrence caused by overexertion person, the dense juice clothes of decocting." medicine clinical research shows; the contained Hesperidin of Pericarpium Citri Reticulatae can suppress gastric ulcer; reduce capillary permeability; have the gastrointestinal function of adjustment and antiinflammatory action; its volatile oil has eliminating the phlegm, relievings asthma, facilitating digestion liquid secretion and get rid of the effects such as enteral pneumatosis, also has in addition coronary artery dilator, reduces blood pressure and the effect such as function of gallbladder promoting.
Rhizoma Cyperi: acrid in the mouth; Cold nature; Nontoxic.Return liver; Lung; Spleen; Stomach; Tri-jiao channel.The resolving depression of regulating the flow of vital energy.Cure mainly distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation; Vomiting and nausea." detailed outline " carries: " the cold epidemic disease of loose seasonal epidemic pathogens, sharp three warmers, Xie Nvyu, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot, abdominal distention, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer sores, spits blood, hematochezia." modern medicine study proves that Rhizoma Cyperi energy nervous system regulation function has heart tonifying, decreased heart rate, reduces blood pressure, prevents and treats the effect such as hyperlipemia and atherosclerosis.
Rhizoma Pinelliae Preparatum: acrid in the mouth; Warm in nature; Be slightly cold.Enter spleen; Stomach warp.Drying dampness to eliminate phlegm; Sending down the abnormal ascending QI preventing or arresting vomitting; Dissolving lump and resolving mass; Outer subduing inflammation." not Lu " carries: " subduing inflammation, treat sallow, happy damp appearance." modern medicine study confirmation, the Rhizoma Pinelliae has significant antitussive effect, can suppress the secretion of body of gland, suppresses tryptic hydrolysis, also has in addition blood pressure lowering, blood coagulation, the fissional effect of promotion.
Radix Bupleuri: bitter in the mouth; Pungent; Cold nature.Enter liver; Gallbladder meridian.Induce sweat and bring down a fever; Dispersing the stagnated live-QI to relieve the stagnation of QI; Elevate a turnable ladder yang-energy.Cure mainly fever caused by exogenous pathogens; Alternate attack of chill and fever; Malaria; Hypochondriac pain due to stagnation of liverQI mammary swelling; Headache dizziness gastroptosis." Japan hanako materia medica " carries: " mend five kinds of strain and seven kinds of impairment, relieving restlessness spasmolytic, physical strength profiting, expectorant antitussive, profit cardiopulmonary." modern medicine study shows; Radix Bupleuri is containing compositions such as volatile oil, fat, and decoct has refrigeration function, and tubercule bacillus and influenza virus are had to inhibitory action; contained Saponin has sedation and analgesia effect, and has anti-liver injury, prevents the function of steatosis and fibroplasia, reduction transaminase and function of gallbladder promoting.
Radix Paeoniae Rubra: bitter in the mouth; Be slightly cold.Return Liver Channel.Clearing away heat and cooling blood; Eliminating stasis to stop pain.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis; Conjunctival congestion and swelling pain; Hypochondriac pain due to stagnation of liverQI; Amenorrhea dysmenorrhea; Lump in the abdomen stomachache; Injury from falling down; Carbuncle skin infection.Shennong's Herbal carries: " bitter in the mouth is flat, and main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending cold and heat hernia abdominal mass, pain relieving, raw Semen Coicis." modern medicine study confirms; Radix Paeoniae Rubra is to the change effect of hemorheological property of the viscid blood patients with coronary heart disease of height; can make whole blood viscosity when erythrocyte electrophoretic time reduce; can pass through to affect calcium metabolism antagonism atherosclerosis; water-alcohol extraction has significant sedation and analgesic effect; can slightly improve the acidity of gastric juice, can be used for improving appetite, digestive function and some neuropathy.
Bulbus Lilii: sweet in the mouth; Micro-hardship.Cold nature.Enter the heart; Lung meridian.Nourishing YIN and moistening the lung; Clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough; Sputum mixed with blood; The calentura later stage; Waste heat is unclear; Or the fidgets due to deficiency palpitation with fear of feelings will due to unsuccessful; Insomnia and dreamful sleep; Absentminded; Carbuncle; Eczema." Japan hanako materia medica " carries: " feel at ease, determine gallbladder, beneficial will, supports the five internal organs.Xie acute mastitis, carbuncle on the back and all skin ulcers are swollen." modern medicine study shows, Bulbus Lilii have significantly eliminate the phlegm, antitussive effect, to adrenal cortex function, exhaustion has significant protective effect, extends hypoxia endurance time, the effect that also has in addition calmness, nourishing YIN and moistening the lung, anticancer to breed.
Rhizoma Corydalis: acrid in the mouth; Bitter; Warm in nature; Nontoxic.Enter liver; Stomach; The heart; Lung; Spleen channel.Invigorate blood circulation; Dissipating blood stasis; Regulate the flow of vital energy; Pain relieving.Cure mainly all pains of trusted subordinate's waist knee joint." detailed outline " carries: " stagnation of QI in energy promoting the circulation of blood, stasis in gas, thus specially control upper and lower all pains all over the body, among using, simply fantastic.Invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis." modern medicine study shows, Rhizoma Corydalis has significant analgesia, calmness, hypnosis, stable effect, and excited gastrointestinal smooth muscle, significantly expands coronary vasodilator, can cause the secretion of PATH, and muscle is had to relaxation effect.
Radix Curcumae: acrid in the mouth; Bitter; Cold in nature.Enter the heart; Liver; Gallbladder meridian.The relieving convulsion of invigorating blood circulation; Promoting QI circulation for relieving depression; Removing heat from blood clears away heart-fire; Depressed liver-energy dispersing and function of gallbladder promoting.Cure mainly all pains of breast abdomen side of body rib; WEIJIA caking; Calentura coma; Demented; Infantile convulsion; Spit blood; Epistaxis; Stranguria with blood; Sand Stranguria; Jaundice.Essentials of Matea Medica carries: " circulation of qi promoting, resolving depression; Let out blood, removing blood stasis with potent drugs.Cool heat in the heart, loose stagnation of liver-QI, can open the strongly fragrant of lung gold." modern medicine study confirmation, Radix Curcumae is rich in Radix Curcumae polysaccharide, has the reticuloendothelial system of enhancing activity, and ethanol extract, on the original obvious impact of fibrin, can reduce T-CHOL and content of triglyceride in aorta.
The present invention compared with prior art, has following beneficial effect:
Reasonable recipe of the present invention, take detumescence and promoting granulation medicine as monarch, it is minister that blood stasis dispelling removes full medicine, and heat clearing away is assistant, dampness is for making, regulating qi and dredging collateral, warming middle-JIAO for easing the stomach, effectively activating machine vitality of subject, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, through clinical verification, the chronic gastritis of non-atrophic, atrophic and specific type is all had to good therapeutic effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of effective ingredient of the present invention are:
Rhizoma Dioscoreae 62g Fructus Aurantii 56g Radix Glycyrrhizae Preparata 53g Radix Aucklandiae 50g
Cortex Cinnamomi 46g Radix Scutellariae 42g Fructus Evodiae 39g Rhizoma Sparganii 36g
Pericarpium Citri Reticulatae 32g Rhizoma Cyperi 29g Rhizoma Pinelliae Preparatum 25g Radix Bupleuri 22g
Radix Paeoniae Rubra 19g Bulbus Lilii 16g Rhizoma Corydalis 12g Radix Curcumae 10g.
The processing step of process for preparing medicine of the present invention is:
(1) Rhizoma Dioscoreae is smash as pasty state, add after the water of same deal, elimination residue, mass is for subsequent use.
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use.
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to vinegar exhaustion, use slow fire fried dry, after pulverizing, grind into powder, cross 140 order fine powders, for subsequent use.
(4) Bulbus Lilii is mixed thoroughly with refined honey, fry and be slightly coke yellow to surface and when tack-free with slow fire, after taking out and cooling, grind into powder, cross 140 order fine powders, for subsequent use.
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Sparganii, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; In remaining medicinal residues, add again the water of four times of amounts, soak after 3～5 hours, get immersion; Merge twice gained immersion, heating evaporation, under 50 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use.
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soak
3～5 hours, get immersion; In remaining medicinal residues, add again the shao-hsing rice wine of doubling dose, boil rear continuation and soak 2～3 hours, get immersion; Merge twice gained immersion, heating evaporation, under simmer down to room temperature environment, the thick paste of relative density 1.15～1.20, for subsequent use.
(7) mass step (1) being made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and after stirring, quick-freezing becomes powder, is prepared as tablet product with modern science technique.
Usage and dosage: adult every day 2 times, getting up early and sleep before respectively take 1 time, each 0.75～1.0g, with warm water delivery service.Patient with severe symptoms adds 1 time depending on state of an illness clothes every day, or follows the doctor's advice.Within 5 days, be a course for the treatment of, take effect general 2～3 courses for the treatment of.
Embodiment 2
Raw material composition and the weight of effective ingredient of the present invention are:
Rhizoma Dioscoreae 57g Fructus Aurantii 53g Radix Glycyrrhizae Preparata 50g Radix Aucklandiae 46g
Cortex Cinnamomi 41g Radix Scutellariae 38g Fructus Evodiae 35g Rhizoma Sparganii 32g
Pericarpium Citri Reticulatae 29g Rhizoma Cyperi 25g Rhizoma Pinelliae Preparatum 22g Radix Bupleuri 19g
Radix Paeoniae Rubra 15g Bulbus Lilii 13g Rhizoma Corydalis 10g Radix Curcumae 7g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of effective ingredient of the present invention are:
Rhizoma Dioscoreae 54g Fructus Aurantii 48g Radix Glycyrrhizae Preparata 45g Radix Aucklandiae 42g
Cortex Cinnamomi 38g Radix Scutellariae 35g Fructus Evodiae 32g Rhizoma Sparganii 28g
Pericarpium Citri Reticulatae 25g Rhizoma Cyperi 22g Rhizoma Pinelliae Preparatum 19g Radix Bupleuri 15g
Radix Paeoniae Rubra 13g Bulbus Lilii 10g Rhizoma Corydalis 8g Radix Curcumae 5g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
Show according to the court and outer court's Patients with Chronic Gastritis treatment data tracing, medicine of the present invention reaches 92.13% to the effective percentage of non-chronic atrophic gastritis, effective percentage to chronic atrophic gastritis reaches 81.25%, effective percentage to specific type chronic gastritis reaches 75.62%, especially gastric antrum gastritis and body of stomach gastritis are had to fabulous curative effect, meet the drug effect standard of clinical treatment chronic gastritis completely, be suitable for clinical prevention and treat chronic gastritis and apply.
Claims (4)
1. a medicine that is used for the treatment of chronic gastritis, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
38～54 parts of 42～58 parts of Radix Aucklandiae of 45～60 parts of Radix Glycyrrhizae Preparatas of 50～65 parts of Fructus Aurantiis of Rhizoma Dioscoreae
25～40 parts of 28～44 parts of Rhizoma Sparganii of 30～46 parts of Fructus Evodiaes of 34～50 parts of Radix Scutellariaes of Cortex Cinnamomi
12～25 parts of 15～28 parts of Radix Bupleuri of 18～32 parts of Rhizoma Pinelliae Preparatum of 22～36 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
3～12 parts of 5～15 portions of Radix Curcumaes of 8～18 parts of Rhizoma Corydalis of 10～22 portions of Bulbus Liliies of Radix Paeoniae Rubra,
Described in making, be used for the treatment of the preparation method of the medicine of chronic gastritis, comprise following processing step:
(1) Rhizoma Dioscoreae is smash as pasty state, add after the water of same deal, elimination residue, mass is for subsequent use;
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use;
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to vinegar exhaustion, use slow fire fried dry, after pulverizing, grind into powder, cross 140 order fine powders, for subsequent use;
(4) Bulbus Lilii is mixed thoroughly with refined honey, fry and be slightly coke yellow to surface and when tack-free with slow fire, after taking out and cooling, grind into powder, cross 140 order fine powders, for subsequent use;
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Sparganii, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; In remaining medicinal residues, add again the water of four times of amounts, soak after 3～5 hours, get immersion; Merge twice gained immersion, heating evaporation, under 50 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use;
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soak 3～5 hours, get immersion; In remaining medicinal residues, add again the shao-hsing rice wine of doubling dose, boil rear continuation and soak 2～3 hours, get immersion; Merge twice gained immersion, heating evaporation, under simmer down to room temperature environment, the thick paste of relative density 1.15～1.20, for subsequent use;
(7) mass step (1) being made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and after stirring, quick-freezing becomes powder, is prepared as tablet product with modern science technique.
2. a kind of medicine that is used for the treatment of chronic gastritis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
42～50 parts of 45～55 parts of Radix Aucklandiae of 48～58 parts of Radix Glycyrrhizae Preparatas of 52～62 parts of Fructus Aurantiis of Rhizoma Dioscoreae
28～36 parts of 30～40 parts of Rhizoma Sparganii of 33～43 parts of Fructus Evodiaes of 36～46 parts of Radix Scutellariaes of Cortex Cinnamomi
15～23 parts of 18～26 parts of Radix Bupleuri of 21～29 parts of Rhizoma Pinelliae Preparatum of 25～33 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
5～9 parts of 8～12 portions of Radix Curcumaes of 10～16 parts of Rhizoma Corydalis of 12～18 portions of Bulbus Liliies of Radix Paeoniae Rubra.
3. a kind of medicine that is used for the treatment of chronic gastritis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
46 parts of 50 parts of Radix Aucklandiae of 53 parts of Radix Glycyrrhizae Preparatas of 57 parts of Fructus Aurantiis of Rhizoma Dioscoreae
32 parts of 35 parts of Rhizoma Sparganii of 38 parts of Fructus Evodiaes of 41 parts of Radix Scutellariaes of Cortex Cinnamomi
19 parts of 22 parts of Radix Bupleuri of 25 parts of Rhizoma Pinelliae Preparatum of 29 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
7 parts of 10 portions of Radix Curcumaes of 13 parts of Rhizoma Corydalis of 15 portions of Bulbus Liliies of Radix Paeoniae Rubra.
4. a preparation method that is used for the treatment of the medicine of chronic gastritis as described in claim 1-3 any one, is characterized in that: comprise following processing step:
(1) Rhizoma Dioscoreae is smash as pasty state, add after the water of same deal, elimination residue, mass is for subsequent use;
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use;
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to vinegar exhaustion, use slow fire fried dry, after pulverizing, grind into powder, cross 140 order fine powders, for subsequent use;
(4) Bulbus Lilii is mixed thoroughly with refined honey, fry and be slightly coke yellow to surface and when tack-free with slow fire, after taking out and cooling, grind into powder, cross 140 order fine powders, for subsequent use;
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Sparganii, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; In remaining medicinal residues, add again the water of four times of amounts, soak after 3～5 hours, get immersion; Merge twice gained immersion, heating evaporation, under 50 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use;
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soak 3～5 hours, get immersion; In remaining medicinal residues, add again the shao-hsing rice wine of doubling dose, boil rear continuation and soak 2～3 hours, get immersion; Merge twice gained immersion, heating evaporation, under simmer down to room temperature environment, the thick paste of relative density 1.15～1.20, for subsequent use;
(7) mass step (1) being made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and after stirring, quick-freezing becomes powder, is prepared as tablet product with modern science technique.
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