CN103055271A - Medicament for treating chronic gastritis and preparation method of medicament - Google Patents
Medicament for treating chronic gastritis and preparation method of medicament Download PDFInfo
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Abstract
The invention discloses a medicament for treating chronic gastritis and a preparation method of the medicament, belonging to the field of the traditional Chinese medicine. The medicament comprises the following effective components in parts by weight: 50-65 parts of Chinese yam, 45-60 parts of bitter orange, 42-58 parts of prepared liquorice root, 38-54 parts of costustoot, 34-50 parts of cinnamon, 30-46 parts of baikal skullcap root, 28-44 parts of medicinal evodia fruit, 25-40 parts of common burreed rhizome, 22-36 parts of tangerine peel, 18-32 parts of nutgrass galingale rhizome, 15-28 parts of rhizoma pinellinae praeparata, 12-25 parts of radix bupleuri, 10-22 parts of radix paeoniae rubra, 8-18 parts of lily, 5-15 parts of rhizoma corydalis and 3-12 parts of turmeric root-tuber. According to the medicament, the formulation is reasonable; the medicine for relieving swelling and promoting tissue regeneration is taken as the monarch, the medicine for dispersing blood stasis and eliminating fullness is as the minister, and the medicine for clearing heat is as the assistant and the medicine for eliminating dampness is as the guide; by regulating vital energy, dredging collaterals, warming the middle and harmonizing stomach, the medicament is effective in activating the vitality of the body and has good absorption effect, obvious healing effect, no toxic or side effect and no clinical adverse reaction. Through clinical verifications, the medicament has relatively good treatment effect on non-atrophic chronic gastritis, atrophic chronic gastritis and special chronic gastritis.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine and preparation method that is used for the treatment of chronic gastritis.
Background technology
Chronic gastritis is the gastric mucosa chronic inflammatory disease that is caused by the various causes of disease, according to histopathology change and pathological changes at the distribution position of stomach, in conjunction with the possible cause of disease, chronic gastritis can be divided into non-atrophic, atrophic and specific type three major types.Chronic non-atrophic gastritis refer to without Mucosal atrophy sexually revise, gastric mucosa layer sees take lymphocyte and the plasma cell chronic gastritis as main chronic inflammatory cell infiltration; Chronic atrophic gastritis refers to that the chronic gastritis that atrophic changes has occured gastric mucosa; Specific type gastritis kind is a lot, and is due to different pathogeny, more rare clinically.
Helicobacter pylori be chronic gastritis topmost pathogenic because of, helicobacter pylori causes primary cellular defect by producing the materials such as ammonia effect, secretion VacA A, its cytotoxin-associated gene protein can cause strong inflammatory reaction, its thalline cell wall also can be used as the antigen induction immunoreation, causes the chronic inflammatory disease of gastric mucosa.Worldwide comparative study shows that the regional difference of atrophy and the living incidence rate of intestinalization parallels with the difference of interzone incidence gastric cancer rate substantially, and the generation of this prompting chronic gastritis and development also relate to other factors outside the helicobacter pylori infections.Up-to-date medical research finds that the morbidity of chronic gastritis and autoimmunity also have considerable relatedness, and autoimmunity gastritis originally can have other autoimmune diseases such as chronic lymphocytic thyroiditis, vitiligo etc. take the body of stomach mucosal atrophy that is rich in parietal cell as main.
Modern medicine carries out eradication therapy to the treatment of chronic gastritis mainly for helicobacter pylori, is specially adapted to, dysplasia person living with gastric mucosal erosion, atrophy and intestinalization; The person that has the indigestion symptom; Gastric cancer family history person is arranged, usually adopt three radical cure schemes, to effecting a radical cure the tetrad scheme of the failed bismuth-containing selected agent.Experiential therapy to functional dyspepsia; adopt and press down acid or antacid such as ranitidine or omeprazole capsule, short digestive tract power reinforcing medicine such as many kinds of vertical ketone sheets, gastric mucosal protection medicine such as sucralfate chewable tablet etc.; these medicines also have certain effect to gastric epithelial reparation and inflammation except the symptomatic treatment effect.But all there is certain side effect in above-mentioned all medicines, can not mode active by excitating organism, that regulate immunity of organisms remove the chronic inflammatory disease old complaint.
Traditional Chinese medical theory is thought, it is owing to stagnation of QI causing retention of food, stomach-QI being unable to descend normally that stomach characterizes, pathogenic fire derived from stagnation of liver-QI, pathogen usually intruding into collateral in protracted disease, Deficiency and coldness of spleen and stomach, qi depression to blood stasis, stagnation of liver-QI cold syndrome of the stomach, the reasons such as insufficiency of stomach blood stasis cause, reach the purpose of radical cure chronic gastritis, adjusting gastrointestinal function, should start with except full, heat clearing and damp drying, detumescence and promoting granulation, warming middle-JIAO for easing the stomach from regulating qi and dredging collateral, blood stasis dispelling, select Chinese prescription rationally to concoct and be used as medicine.
Summary of the invention
The invention provides a kind of medicine and preparation method that is used for the treatment of chronic gastritis, have regulating qi and dredging collateral, blood stasis dispelling except the effect of full, heat clearing and damp drying, detumescence and promoting granulation, warming middle-JIAO for easing the stomach, cure the disease and ask the source, the various chronic gastritis that a variety of causes is caused all has good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of medicine that is used for the treatment of chronic gastritis, raw material composition and the parts by weight of making described effective ingredient are:
38～54 parts of 42～58 parts of Radix Aucklandiae of 45～60 parts of Radix Glycyrrhizae Preparatas of 50～65 parts of Fructus Aurantiis of Rhizoma Dioscoreae
25～40 parts of 28～44 parts of rhizoma sparganic of 30～46 parts of Fructus Evodiaes of 34～50 parts of Radix Scutellariaes of Cortex Cinnamomi
12～25 parts of 15～28 parts of Radix Bupleuri of 18～32 parts of Rhizoma Pinelliae Preparatum of 22～36 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
3～12 parts of 5～15 portions of Radix Curcumaes of 8～18 parts of Rhizoma Corydalis of 10～22 portions of Bulbus Liliies of Radix Paeoniae Rubra.
Raw material composition and the parts by weight of making described effective ingredient are:
42～50 parts of 45～55 parts of Radix Aucklandiae of 48～58 parts of Radix Glycyrrhizae Preparatas of 52～62 parts of Fructus Aurantiis of Rhizoma Dioscoreae
28～36 parts of 30～40 parts of rhizoma sparganic of 33～43 parts of Fructus Evodiaes of 36～46 parts of Radix Scutellariaes of Cortex Cinnamomi
15～23 parts of 18～26 parts of Radix Bupleuri of 21～29 parts of Rhizoma Pinelliae Preparatum of 25～33 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
5～9 parts of 8～12 portions of Radix Curcumaes of 10～16 parts of Rhizoma Corydalis of 12～18 portions of Bulbus Liliies of Radix Paeoniae Rubra.
Raw material composition and the parts by weight of making described effective ingredient are:
46 parts of 50 parts of Radix Aucklandiae of 53 parts of Radix Glycyrrhizae Preparatas of 57 parts of Fructus Aurantiis of Rhizoma Dioscoreae
32 parts of 35 parts of rhizoma sparganic of 38 parts of Fructus Evodiaes of 41 parts of Radix Scutellariaes of Cortex Cinnamomi
19 parts of 22 parts of Radix Bupleuri of 25 parts of Rhizoma Pinelliae Preparatum of 29 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
7 parts of 10 portions of Radix Curcumaes of 13 parts of Rhizoma Corydalis of 15 portions of Bulbus Liliies of Radix Paeoniae Rubra.
A kind of preparation method that is used for the treatment of the medicine of chronic gastritis comprises following processing step:
(1) Rhizoma Dioscoreae smash be pasty state, add the water with deal after, the elimination residue, mass is for subsequent use.
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use.
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to the vinegar exhaustion, use the slow fire fried dry, grind into powder after the pulverizing, cross 140 order fine powders, for subsequent use.
(4) Bulbus Lilii is mixed thoroughly with refined honey, fries with slow fire and slightly be coke yellow to the surface and when tack-free, take out cool after, grind into powder, cross 140 order fine powders, for subsequent use.
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, rhizoma sparganic, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; The water that adds again four times of amounts in remaining medicinal residues soaked after 3～5 hours, got immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.10～1.15 is for subsequent use under 50 ℃ of environment of simmer down to.
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soaked 3～5 hours, get immersion; The shao-hsing rice wine that adds again doubling dose in remaining medicinal residues boils rear continuation and soaked 2～3 hours, gets immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.15～1.20 is for subsequent use under the simmer down to room temperature environment.
(7) mass that step (1) is made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and the rear quick-freezing that stirs becomes powder, is prepared as the tablet product with modern science technique.
The property of medicine of the used Chinese medicine of the present invention is as follows:
Rhizoma Dioscoreae: sweet in the mouth; Property is put down.Enter lung; Spleen; Kidney channel.Spleen reinforcing; Support lung; Reinforce the kidney; Benefit is smart.Cure mainly diarrhea due to hypofunction of the spleen; The lack of appetite edema; Cough and asthma due to lung deficiency; Quench one's thirst; Seminal emission; Leukorrhagia; The frequent micturition of suffering from a deficiency of the kidney; Carbuncle is controlled in external; Scrofula." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency is grown essence and is reinforced the kidney, and controls weakness, treats five kinds of strain and seven kinds of impairment." modern medicine study confirms, Rhizoma Dioscoreae can blood sugar lowering, regulates body to non-specific irritant reaction, effectively resists the Immunosuppression effect of cyclophosphamide, stimulates intestinal motility, promotes that intestinal contents is emptying, in addition can also be aid digestion, antidiarrheal, eliminate the phlegm.
Fructus Aurantii: bitter in the mouth; Acid; Cold nature.Enter lung; Spleen; Liver; Stomach; Large intestine channel.The chest stuffiness relieving of regulating the flow of vital energy; The stagnant removing food stagnancy of row.Cure mainly the septum pectorale feeling of fullness; Distending pain over the hypochondrium; Accumulation of food in the stomach and intes tine due to indigestion; Distension and fullness in the abdomen; Heavy behind the dysentery; Proctoptosis; Uterine prolapse." detailed outline " carries: " control thoracic obstruction feeling of fullness, take Fructus Aurantii Immaturus as key medicine, all sides control the inferior internal hemorrhoid with bleeding dysentery, the secret plug of large intestine, and tenesmus, take Fructus Aurantii as general, then Fructus Aurantii Immaturus is not only controled the inferior again, and Fructus Aurantii is not only controlled height also." clinic study shows that Fructus Aurantii has the effect of significant resisting pathogenic microbes, suppresses allergy, also have in addition calmness, diuresis, excited uterus, heart tonifying, boost, the effect such as function of gallbladder promoting.
Radix Glycyrrhizae Preparata: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; The stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " Radix Glycyrrhizae is monarch in all medicines.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine meritorious." the modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have in addition anti-gastric-ulcer, gastritis effect.
The Radix Aucklandiae: acrid in the mouth; Bitter; Cold in nature; Slightly poisonous.Enter lung; The stomach warp.Promoting the circulation of QI to relieve pain; Removing toxic substances and promoting subsidence of swelling; The suppressing the hyperactive liver blood pressure lowering.Cure mainly breast side of body epigastric pain; Colicky; Intestinal is scorching; Dysentery stomachache; The cough phlegm dyspnea; Snake bite and insect sting; The carbuncle furuncle; Eczema; Skin pruritus; Hypertension." book on Chinese herbal medicine meets former " carries: " control large intestine, control wind syndrome of head, pruritus, tinea alba." clinic study shows; Radix Aucklandiae preparation has certain hypotensive effect; the Radix Aristolochiae total alkaloids has in various degree inhibitory action to staphylococcus aureus, bacillus pyocyaneus, escherichia coli and modification bacillus; can improve non-specific antibody; strengthen the activate the phagocytic capacity of peritoneal macrophage; the defensive enginery of enhancing body, also have in addition calm, emetic action.
Cortex Cinnamomi: acrid in the mouth; Bitter; Hot in nature.Enter kidney; Spleen; The heart; Liver Channel.It is supporing yang to mend fire; Let the fire back to its origin; Dispersing cold for relieving pain; Warming the meridian and promoting blood circulation.The mainly treating intolerance of cold cold extremities; The dyspnea with rapid and short breath of losing heart; Decline of the fire from the gate of life; Fire is Gui Yuan not; The flushed complexion cold foot; Dizziness and tinnitus; Dispute is rotten broken; Spleen-kidney vacuity cold; Coldness and pain in the epigastrium; The decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain." property of medicine opinion " carries: " cure mainly nine types of precordial pain, kill three worms, main removing blood stasis, the tonneau moon closes, and controls weak foot, and numbness, meciless except cough with dyspnea, stagnation of QI, is gathered around numbness, ends cold air in the abdomen, and is unbearably painful." the modern medicine study confirmation, Cortex Cinnamomi contains the compositions such as cinnamic aldehyde, cinnamyl acetate, acetoxyphenyl group the third cheese, has the effect of fragrant stomach invigorating, antipyretic-antalgic, anti-inflammation.
Radix Scutellariae: bitter in the mouth; Cold in nature.Return lung; Gallbladder; Spleen; Stomach; Large intestine; Small intestine meridian.Heat clearing and damp drying; Eliminating fire and detoxication; Blood pressure lowering.Cure mainly hygropyrexia, heat-damp in summer vomiting and nausea uncomfortable in chest; Damp and hot feeling of fullness; Dysentery; Jaundice; The cough due to lung-heat; Heat in blood is told nosebleed; Carbuncle sore tumefacting virus." herbal classic " carries: " main all hot jaundice, intestinal is out-of-the-way, lets out profit, relieves oedema or abdominal distension through diuresis or purgation acute scleritis." modern medicine study confirms, Radix Scutellariae has the significantly effects such as antibacterial, antifungal, antiviral, antiinflammatory, antiallergic action, can reduce blood pressure, anticoagulant, anticoagulant, blood fat reducing, protects the liver in addition in addition, function of gallbladder promoting, antioxidation, anticancer function.
Fructus Evodiae: acrid in the mouth; Bitter; Hot in nature; Mild toxicity.Enter liver; Stomach; Spleen; Large intestine; Kidney channel.Dispersing cold for relieving pain; The soothing the liver therapeutic method to keep the adverse QI flowing downwards; Warming middle-JIAO dampness.Cure mainly coldness and pain in the epigastrium; Headache due to JUE YIN disorder; Colic; Beriberi swells and ache; The vomiting acid regurgitation; Cold-damp is had loose bowels.Compendium of Material Medica is carried: " dissipating depression of QIization stagnates, and controls acid regurgitation, the cloudy sputum headache of fainting, and insidious stomachache, hernia, dysentery, mouthpiece's mouth is choked." the modern medicine study confirmation, Fructus Evodiae has the town to tell, antidiarrheal, and antiulcer suppresses the stomach motion, and heart tonifying rises blood pressure, and shock improves microcirculation, improves the effects such as immunologic function.
Rhizoma sparganic: acrid in the mouth; Puckery; Cool in nature.Enter liver; Spleen channel.The removing blood stasis circulation of qi promoting; The removing food stagnancy pain relieving.Cure mainly the lump in the abdomen mass in the abdomen; The stasis of blood amenorrhea that stagnates; Dysmenorrhea; The food stagnation distending pain; Traumatic pain." Japan hanako materia medica " carries: " it is uncomfortable to control married woman's blood vessels, cardiac and abdominal pain, and the tire that falls, the stagnant blood that disappears is mended labor, and flatulence is controlled in logical menstruation, disappears and pounces on the damage blood stasis, and puerperal abdonimal pain, blood fortune and stagnated blood are not lower." modern medicine study confirms that rhizoma sparganic can be strengthened intestinal tube and shrink, and there is excitation in the uterus, can anticoagulant, prolong thrombus formation time, melt thrombosis, reduce whole blood viscosity.
Pericarpium Citri Reticulatae: acrid in the mouth; Sweet; Cold in nature.Enter spleen; The stomach warp.The therapeutic method to keep the adverse QI flowing downwards; In the accent; Reduce phlegm; Relieving alcoholic intoxication.Cure mainly drinking and eating irregularly; Upper gas stuffy sensation with restlessness; It is thirsty to get sick from drinking too much wine." Japan hanako materia medica " carries: " skin is processed and is made soup, but alcoholic intoxication and wine are thirsty, typhoid fever diet recurrence caused by overexertion person, the dense juice clothes of frying in shallow oil." medicine clinical research shows; the contained Hesperidin of Pericarpium Citri Reticulatae can suppress gastric ulcer; reduce capillary permeability; have the gastrointestinal function of adjustment and antiinflammatory action; its volatile oil has eliminating the phlegm, relievings asthma, facilitating digestion liquid secretion and get rid of the effect such as enteral pneumatosis, also has in addition coronary artery dilator, reduces blood pressure and the effect such as function of gallbladder promoting.
Rhizoma Cyperi: acrid in the mouth; Cold nature; Nontoxic.Return liver; Lung; Spleen; Stomach; Tri-jiao channel.The resolving depression of regulating the flow of vital energy.Cure mainly distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; The belch acid regurgitation; Vomiting and nausea." detailed outline " carries: " the cold epidemic disease of loose seasonal epidemic pathogens, sharp three warmers, Xie Nvyu, the diet that disappears gathers, the phlegm retention feeling of fullness, edema of dorsum of the foot, abdominal distention, beriberi is ended trusted subordinate, limbs, head, order, tooth, all pains of ear, and ulcer sores is spitted blood hematochezia." modern medicine study proves, Rhizoma Cyperi can the nervous system regulation function, heart tonifying, decreased heart rate is arranged, reduce blood pressure, prevent and treat the effects such as hyperlipemia and atherosclerosis.
Rhizoma Pinelliae Preparatum: acrid in the mouth; Warm in nature; Be slightly cold.Enter spleen; The stomach warp.Drying dampness to eliminate phlegm; The sending down the abnormal ascending QI preventing or arresting vomitting; Dissolving lump and resolving mass; Outer subduing inflammation." not Lu " carries: " subduing inflammation, treats sallow, happy damp appearance." the modern medicine study confirmation, the Rhizoma Pinelliae has significant antitussive effect, can suppress the secretion of body of gland, suppresses tryptic hydrolysis, also has in addition blood pressure lowering, blood coagulation, the fissional effect of promotion.
Radix Bupleuri: bitter in the mouth; Hot; Cold nature.Enter liver; Gallbladder meridian.Induce sweat and bring down a fever; Dispersing the stagnated live-QI to relieve the stagnation of QI; The elevate a turnable ladder yang-energy.Cure mainly fever caused by exogenous pathogens; Alternate attack of chill and fever; Malaria; The hypochondriac pain due to stagnation of liverQI mammary swelling; Headache dizziness gastroptosis." Japan hanako materia medica " carries: " mend five kinds of strain and seven kinds of impairment, relieving restlessness spasmolytic, physical strength profiting, expectorant antitussive, profit cardiopulmonary." modern medicine study shows; Radix Bupleuri contains the compositions such as volatile oil, fat, and decoct has refrigeration function, and tubercule bacillus and influenza virus are had inhibitory action; contained Saponin has the sedation and analgesia effect, and has anti-liver injury, prevents the function of steatosis and fibroplasia, transaminase lowering and function of gallbladder promoting.
Radix Paeoniae Rubra: bitter in the mouth; Be slightly cold.Return Liver Channel.Clearing away heat and cooling blood; Eliminating stasis to stop pain.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis; Conjunctival congestion and swelling pain; Hypochondriac pain due to stagnation of liverQI; The amenorrhea dysmenorrhea; Lump in the abdomen stomachache; Injury from falling down; The carbuncle skin infection.Shennong's Herbal carries: " bitter in the mouth is flat, and main pathogen stomachache except arthralgia due to stagnation of blood, broken hard long-pending cold and heat hernia abdominal mass, pain relieving, is given birth to Semen Coicis." modern medicine study confirms; Radix Paeoniae Rubra is to the change effect of hemorheological property of the viscid blood patients with coronary heart disease of height; can make whole blood viscosity when erythrocyte electrophoretic time reduce; can pass through to affect calcium metabolism antagonism atherosclerosis; water-alcohol extraction has significant sedation and analgesic effect; can slightly improve the acidity of gastric juice, can be used for improving appetite, digestive function and some neuropathy.
Bulbus Lilii: sweet in the mouth; Little hardship.Cold nature.Enter the heart; Lung meridian.Nourishing YIN and moistening the lung; Clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough; Sputum mixed with blood; The calentura later stage; Waste heat is unclear; Or the fidgets due to deficiency palpitation with fear of feelings will due to unsuccessful; Insomnia and dreamful sleep; Absentminded; Carbuncle; Eczema." Japan hanako materia medica " carries: " feel at ease, decide gallbladder, beneficial will is supported the five internal organs.Xie acute mastitis, carbuncle on the back and all skin ulcers are swollen." modern medicine study shows, Bulbus Lilii have significantly eliminate the phlegm, antitussive effect, depletion has significant protective effect to adrenal cortex function, prolongs hypoxia endurance time, the effect that also has in addition calmness, nourishing YIN and moistening the lung, anticancer to breed.
Rhizoma Corydalis: acrid in the mouth; Bitter; Warm in nature; Nontoxic.Enter liver; Stomach; The heart; Lung; Spleen channel.Invigorate blood circulation; Dissipating blood stasis; Regulate the flow of vital energy; Pain relieving.Cure mainly all pains of trusted subordinate's waist knee joint." detailed outline " carries: " stagnation of QI in the energy promoting the circulation of blood, stasis in the gas, thus all pains about specially controlling all over the body, among using, simply fantastic.Invigorate blood circulation promoting the circulation of QI, pain relieving, diuresis." modern medicine study shows, Rhizoma Corydalis has significant analgesia, calmness, hypnosis, stable effect, and excited gastrointestinal smooth muscle is significantly expanded coronary vasodilator, can cause the secretion of PATH, and muscle is had relaxation effect.
Radix Curcumae: acrid in the mouth; Bitter; Cold in nature.Enter the heart; Liver; Gallbladder meridian.The relieving convulsion of invigorating blood circulation; Promoting QI circulation for relieving depression; Removing heat from blood clears away heart-fire; Depressed liver-energy dispersing and function of gallbladder promoting.Cure mainly all pains of breast abdomen side of body rib; The WEIJIA caking; The calentura coma; Demented; Infantile convulsion; Spit blood; Epistaxis; Stranguria with blood; Sand Stranguria; Jaundice.Essentials of Matea Medica carries: " circulation of qi promoting, resolving depression; Let out blood, removing blood stasis with potent drugs.Cool heat in the heart, loose stagnation of liver-QI can be opened the strongly fragrant of lung gold." the modern medicine study confirmation, Radix Curcumae is rich in the Radix Curcumae polysaccharide, has the reticuloendothelial system of enhancing activity, and ethanol extract can reduce T-CHOL and content of triglyceride in the aorta to the original obvious impact of fibrin.
The present invention compared with prior art has following beneficial effect:
Reasonable recipe of the present invention, take the detumescence and promoting granulation medicine as monarch, blood stasis dispelling is minister except full medicine, and heat clearing away is assistant, dampness is for making, regulating qi and dredging collateral, warming middle-JIAO for easing the stomach, effectively activating machine vitality of subject, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, through clinical verification the chronic gastritis of non-atrophic, atrophic and specific type all there is preferably therapeutic effect.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Rhizoma Dioscoreae 62g Fructus Aurantii 56g Radix Glycyrrhizae Preparata 53g Radix Aucklandiae 50g
Cortex Cinnamomi 46g Radix Scutellariae 42g Fructus Evodiae 39g rhizoma sparganic 36g
Pericarpium Citri Reticulatae 32g Rhizoma Cyperi 29g Rhizoma Pinelliae Preparatum 25g Radix Bupleuri 22g
Radix Paeoniae Rubra 19g Bulbus Lilii 16g Rhizoma Corydalis 12g Radix Curcumae 10g.
The processing step of process for preparing medicine of the present invention is:
(1) Rhizoma Dioscoreae smash be pasty state, add the water with deal after, the elimination residue, mass is for subsequent use.
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use.
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to the vinegar exhaustion, use the slow fire fried dry, grind into powder after the pulverizing, cross 140 order fine powders, for subsequent use.
(4) Bulbus Lilii is mixed thoroughly with refined honey, fries with slow fire and slightly be coke yellow to the surface and when tack-free, take out cool after, grind into powder, cross 140 order fine powders, for subsequent use.
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, rhizoma sparganic, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; The water that adds again four times of amounts in remaining medicinal residues soaked after 3～5 hours, got immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.10～1.15 is for subsequent use under 50 ℃ of environment of simmer down to.
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soak
3～5 hours, get immersion; The shao-hsing rice wine that adds again doubling dose in remaining medicinal residues boils rear continuation and soaked 2～3 hours, gets immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.15～1.20 is for subsequent use under the simmer down to room temperature environment.
(7) mass that step (1) is made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and the rear quick-freezing that stirs becomes powder, is prepared as the tablet product with modern science technique.
Usage and dosage: adult every day 2 times, getting up early and sleep before respectively take 1 time, each 0.75～1.0g is with warm water delivery service.The patient with severe symptoms looks state of an illness clothes every day and adds 1 time, or follows the doctor's advice.5 days is a course for the treatment of, and take effect general 2～3 courses for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Rhizoma Dioscoreae 57g Fructus Aurantii 53g Radix Glycyrrhizae Preparata 50g Radix Aucklandiae 46g
Cortex Cinnamomi 41g Radix Scutellariae 38g Fructus Evodiae 35g rhizoma sparganic 32g
Pericarpium Citri Reticulatae 29g Rhizoma Cyperi 25g Rhizoma Pinelliae Preparatum 22g Radix Bupleuri 19g
Radix Paeoniae Rubra 15g Bulbus Lilii 13g Rhizoma Corydalis 10g Radix Curcumae 7g.
Process for preparing medicine processing step and the usage and dosage of present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
Rhizoma Dioscoreae 54g Fructus Aurantii 48g Radix Glycyrrhizae Preparata 45g Radix Aucklandiae 42g
Cortex Cinnamomi 38g Radix Scutellariae 35g Fructus Evodiae 32g rhizoma sparganic 28g
Pericarpium Citri Reticulatae 25g Rhizoma Cyperi 22g Rhizoma Pinelliae Preparatum 19g Radix Bupleuri 15g
Radix Paeoniae Rubra 13g Bulbus Lilii 10g Rhizoma Corydalis 8g Radix Curcumae 5g.
Process for preparing medicine processing step and the usage and dosage of present embodiment are identical with embodiment 1.
Clinical data:
Show according to the court and outer court's Patients with Chronic Gastritis treatment data tracing, medicine of the present invention reaches 92.13% to the effective percentage of non-chronic atrophic gastritis, effective percentage to chronic atrophic gastritis reaches 81.25%, effective percentage to the specific type chronic gastritis reaches 75.62%, especially gastric antrum gastritis and body of stomach gastritis there is fabulous curative effect, satisfy the drug effect standard of clinical treatment chronic gastritis fully, be suitable for clinical prevention and apply with the treatment chronic gastritis.
Claims (4)
1. medicine that is used for the treatment of chronic gastritis is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
38～54 parts of 42～58 parts of Radix Aucklandiae of 45～60 parts of Radix Glycyrrhizae Preparatas of 50～65 parts of Fructus Aurantiis of Rhizoma Dioscoreae
25～40 parts of 28～44 parts of rhizoma sparganic of 30～46 parts of Fructus Evodiaes of 34～50 parts of Radix Scutellariaes of Cortex Cinnamomi
12～25 parts of 15～28 parts of Radix Bupleuri of 18～32 parts of Rhizoma Pinelliae Preparatum of 22～36 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
3～12 parts of 5～15 portions of Radix Curcumaes of 8～18 parts of Rhizoma Corydalis of 10～22 portions of Bulbus Liliies of Radix Paeoniae Rubra.
2. a kind of medicine that is used for the treatment of chronic gastritis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
42～50 parts of 45～55 parts of Radix Aucklandiae of 48～58 parts of Radix Glycyrrhizae Preparatas of 52～62 parts of Fructus Aurantiis of Rhizoma Dioscoreae
28～36 parts of 30～40 parts of rhizoma sparganic of 33～43 parts of Fructus Evodiaes of 36～46 parts of Radix Scutellariaes of Cortex Cinnamomi
15～23 parts of 18～26 parts of Radix Bupleuri of 21～29 parts of Rhizoma Pinelliae Preparatum of 25～33 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
5～9 parts of 8～12 portions of Radix Curcumaes of 10～16 parts of Rhizoma Corydalis of 12～18 portions of Bulbus Liliies of Radix Paeoniae Rubra.
3. a kind of medicine that is used for the treatment of chronic gastritis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
46 parts of 50 parts of Radix Aucklandiae of 53 parts of Radix Glycyrrhizae Preparatas of 57 parts of Fructus Aurantiis of Rhizoma Dioscoreae
32 parts of 35 parts of rhizoma sparganic of 38 parts of Fructus Evodiaes of 41 parts of Radix Scutellariaes of Cortex Cinnamomi
19 parts of 22 parts of Radix Bupleuri of 25 parts of Rhizoma Pinelliae Preparatum of 29 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
7 parts of 10 portions of Radix Curcumaes of 13 parts of Rhizoma Corydalis of 15 portions of Bulbus Liliies of Radix Paeoniae Rubra.
4. preparation method that is used for the treatment of the medicine of chronic gastritis is characterized in that: comprise following processing step:
(1) Rhizoma Dioscoreae smash be pasty state, add the water with deal after, the elimination residue, mass is for subsequent use;
(2) Fructus Aurantii, Radix Glycyrrhizae Preparata are ground into powder after pulverizing, crossed 140 order fine powders, for subsequent use;
(3) Rhizoma Cyperi, Rhizoma Corydalis, Radix Curcumae are mixed thoroughly with vinegar, soak into, to the vinegar exhaustion, use the slow fire fried dry, grind into powder after the pulverizing, cross 140 order fine powders, for subsequent use;
(4) Bulbus Lilii is mixed thoroughly with refined honey, fries with slow fire and slightly be coke yellow to the surface and when tack-free, take out cool after, grind into powder, cross 140 order fine powders, for subsequent use;
(5) Radix Aucklandiae, Cortex Cinnamomi, Fructus Evodiae, rhizoma sparganic, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Radix Bupleuri are put into container, add the water of quintuple, soak after 5～7 hours, get immersion; The water that adds again four times of amounts in remaining medicinal residues soaked after 3～5 hours, got immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.10～1.15 is for subsequent use under 50 ℃ of environment of simmer down to;
(6) Radix Scutellariae, Radix Paeoniae Rubra are put into container, add the shao-hsing rice wine of triplication, boil rear continuation and soaked 3～5 hours, get immersion; The shao-hsing rice wine that adds again doubling dose in remaining medicinal residues boils rear continuation and soaked 2～3 hours, gets immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.15～1.20 is for subsequent use under the simmer down to room temperature environment;
(7) mass that step (1) is made, with the fine powder of step (2), step (3), step (4) gained, and the thick paste that step (5), step (6) make mixes, and the rear quick-freezing that stirs becomes powder, is prepared as the tablet product with modern science technique.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107980718A (en) * | 2017-12-08 | 2018-05-04 | 合浦县浦乐牧业有限公司 | Improve live pig immunity and the cultural method of efficiency of feed utilization |
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| CN101703734A (en) * | 2009-09-24 | 2010-05-12 | 苟于洋 | Chinese medicinal preparation for treating gastrosis |
| CN102670962A (en) * | 2012-05-16 | 2012-09-19 | 李承平 | Combined tablet capable of soothing liver and relieving depression |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101703734A (en) * | 2009-09-24 | 2010-05-12 | 苟于洋 | Chinese medicinal preparation for treating gastrosis |
| CN102670962A (en) * | 2012-05-16 | 2012-09-19 | 李承平 | Combined tablet capable of soothing liver and relieving depression |
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| 董斌传等: "中医专方专药治疗萎缩性胃炎进展", 《新消化病学杂志》, vol. 3, no. 4, 31 December 1995 (1995-12-31) * |
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| CN107980718A (en) * | 2017-12-08 | 2018-05-04 | 合浦县浦乐牧业有限公司 | Improve live pig immunity and the cultural method of efficiency of feed utilization |
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