CN108992531A

CN108992531A - A kind of instant particles as Chinese medicine and preparation method thereof for treating the postoperative swelling of fracture of lower limb

Info

Publication number: CN108992531A
Application number: CN201811309601.5A
Authority: CN
Inventors: 霍明昌
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-11-06
Filing date: 2018-11-06
Publication date: 2018-12-14

Abstract

The invention discloses a kind of instant particles as Chinese medicine and preparation method thereof for treating the postoperative swelling of fracture of lower limb, belong to the field of Chinese medicines.The raw material of effective ingredient of the present invention forms are as follows: Ficus lyrata, ramulus cinnamomi, sharpleaf gambirplant root, Rhizoma Atractylodis Macrocephalae, smoothfruit ventilago root and stem, radix achyranthis bidentatae, hirsute gonostegia herb with root, Radix Angelicae Sinensis, radix rehmanniae preparata, herba taxilli, pawpaw, smallflower beggarticks herb, Cortex Araliae Echinocaulis Radicis, Radix Glycyrrhizae, Rhizoma Chuanxiong, heart seven, teasel root, fiveleaf akebia root, radix paeoniae rubra, lycopodium calvatum, thick leaf tree, Zlatostema involucratum Franch. Et savat, pilose triumfetta root and leaf, peach blossom.The present invention suits the remedy to the case for the cause of disease, tonify the liver and kidney, strengthening the spleen and replenishing qi, replenishing and activating blood, warming and activating meridian, blood-activating and qi-promoting, activating microcirculation and removing stasis medicinal, inducing diuresis and reducing edema, swelling and pain relieving, it is clearing heat and detoxicating the effect of, good absorption effect, it is significant in efficacy, treatment method is simple, higher to the postoperative swelling cure rate of fracture of lower limb according to clinical verification.

Description

A kind of instant particles as Chinese medicine and preparation method thereof for treating the postoperative swelling of fracture of lower limb

Technical field

The present invention relates to the field of Chinese medicines more particularly to a kind of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb and its preparations Method.

Background technique

The postoperative swelling of fracture of lower limb is the postoperative most common complication of fracture of lower limb, brings pain to patient, affects The post-operative recovery and normal life of patient.Modern medicine thinks the swelling of the postoperative limbs of fracture of lower limb mainly due to blood vessel after wound Rupture haemorrhage and tissue fluid are oozed out and are caused, and are caused since damage local organization causes vessel wall permeability to increase reflexively Tissue edema, oedema can cause vein and lymphostasis and influence normal blood supply, thus aggravate affected limb swelling, Bubble can be formed extensively.This disease of western medical treatment mainly gives the treatment methods such as anti-inflammatory analgesic hemostasis, ice compress according to the state of an illness, this Although treatment method has certain curative effect, palliative, therapeutic effect is unsatisfactory, and treatment cycle is long, easily repeatedly.

Chinese medicine thinks that qi depression to blood stasis after fracture of lower limb, blood circulating out of vessels is excessive, stops long-pending skin meat reason and hemotoncus then occurs；In turn Qi and blood is unsmooth, dysfunction of the spleen in transportation and transformation, and water-damp retention accumulation part then tension blister even occurs for oedema.This disease of Chinese traditional treatment at present Mainly with activate blood circulation and disperse blood clots, the oral medicinal herb of swelling and pain relieving and external application help the suction of the recession and hemotoncus of swelling after fracture It receives, to treat this disease, although having certain curative effect, treatment is not comprehensive, focuses on local detumescence treatment more.But human body is One organic whole, though hemostasis is the pathology effects consequence of local injured bones and muscles, its physiology function that can influence internal organs qi and blood Energy.

It is considered herein that fracture of lower limb damages, can blood loss gas consumption, and prolonged illness is liied in bed, and gas must be empty, and qi-blood deficiency, body fluid is not Normally defeated cloth is obtained, blood fortune is unsmooth, and meridian stasis closes, and aqueous is stagnated and is swelling.It is considered herein that the wet stasis of blood of the deficiency of vital energy is main pathogenesis, because And the present invention suits the remedy to the case according to the cause of disease, have tonify the liver and kidney, strengthening the spleen and replenishing qi, replenishing and activating blood, warming and activating meridian, blood-activating and qi-promoting, work Blood stagnation resolvation, inducing diuresis and reducing edema, swelling and pain relieving, it is clearing heat and detoxicating the effect of, good absorption effect, can accelerate reduce swelling speed, shorten swelling disappear It moves back the time, improves therapeutic effect and patients ' life quality.

Summary of the invention

The present invention provides a kind of instant particles as Chinese medicine and preparation method thereof for treating the postoperative swelling of fracture of lower limb, have help liver Kidney, strengthening the spleen and replenishing qi, replenishing and activating blood, warming and activating meridian, blood-activating and qi-promoting, activating microcirculation and removing stasis medicinal, inducing diuresis and reducing edema, swelling and pain relieving, it is clearing heat and detoxicating it Effect cures the disease and seeks source treating both manifestation and root cause of disease, all has good curative effect to the postoperative swelling of fracture of lower limb caused by a variety of causes.

To achieve the above object, technical solution of the present invention is implemented as follows:

The raw material composition and parts by weight of the effective ingredient is made in a kind of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb Number are as follows:

25~40 parts of Ficus lyrata, 25~40 parts of ramulus cinnamomi, 25~40 parts of sharpleaf gambirplant root, 20~35 parts of Rhizoma Atractylodis Macrocephalae,

20~35 parts of smoothfruit ventilago root and stem, 20~35 parts of radix achyranthis bidentatae, 20~35 parts of hirsute gonostegia herb with root, 15~30 parts of Radix Angelicae Sinensis,

15~30 parts of radix rehmanniae preparata, 10~25 parts of herba taxilli, 10~25 parts of pawpaw, 10~25 parts of smallflower beggarticks herb,

9~20 parts of Cortex Araliae Echinocaulis Radicis, 9~20 parts of Radix Glycyrrhizae, 9~20 parts of Rhizoma Chuanxiong, 7 6~15 parts of heart,

6~15 parts of teasel root, 6~15 parts of fiveleaf akebia root, 4~12 parts of radix paeoniae rubra, 4~12 parts of lycopodium calvatum,

3~9 parts of thick leaf tree, 3~9 parts of Zlatostema involucratum Franch. Et savat, 2~8 parts of pilose triumfetta root and leaf, 2~8 parts of peach blossom.

The raw material composition and parts by weight of the effective ingredient is made are as follows:

30~36 parts of Ficus lyrata, 30~36 parts of ramulus cinnamomi, 30~36 parts of sharpleaf gambirplant root, 24~30 parts of Rhizoma Atractylodis Macrocephalae,

24~30 parts of smoothfruit ventilago root and stem, 24~30 parts of radix achyranthis bidentatae, 24~30 parts of hirsute gonostegia herb with root, 18~26 parts of Radix Angelicae Sinensis,

18~26 parts of radix rehmanniae preparata, 14~20 parts of herba taxilli, 14~20 parts of pawpaw, 14~20 parts of smallflower beggarticks herb,

12~18 parts of Cortex Araliae Echinocaulis Radicis, 12~18 parts of Radix Glycyrrhizae, 12~16 parts of Rhizoma Chuanxiong, 7 9~12 parts of heart,

9~12 parts of teasel root, 9~12 parts of fiveleaf akebia root, 6~10 parts of radix paeoniae rubra, 6~10 parts of lycopodium calvatum,

5~8 parts of thick leaf tree, 4~7 parts of Zlatostema involucratum Franch. Et savat, 3~6 parts of pilose triumfetta root and leaf, 3~6 parts of peach blossom.

35 parts of Ficus lyrata, 35 parts of ramulus cinnamomi, 32 parts of sharpleaf gambirplant root, 25 parts of Rhizoma Atractylodis Macrocephalae,

25 parts of smoothfruit ventilago root and stem, 25 parts of radix achyranthis bidentatae, 25 parts of hirsute gonostegia herb with root, 24 parts of Radix Angelicae Sinensis,

20 parts of radix rehmanniae preparata, 18 parts of herba taxilli, 18 parts of pawpaw, 16 parts of smallflower beggarticks herb,

15 parts of Cortex Araliae Echinocaulis Radicis, 15 parts of Radix Glycyrrhizae, 15 parts of Rhizoma Chuanxiong, 7 10 parts of heart,

10 parts of teasel root, 10 parts of fiveleaf akebia root, 8 parts of radix paeoniae rubra, 8 parts of lycopodium calvatum,

6 parts of thick leaf tree, 6 parts of Zlatostema involucratum Franch. Et savat, 5 parts of pilose triumfetta root and leaf, 4 parts of peach blossom.

A kind of preparation side of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb of any of claims 1-3 Method comprises the following steps that:

(1) by Ficus lyrata, ramulus cinnamomi, sharpleaf gambirplant root, Rhizoma Atractylodis Macrocephalae, hirsute gonostegia herb with root, herba taxilli, pawpaw, smallflower beggarticks herb, teasel root, Zlatostema involucratum Franch. Et savat, Jenner Fragrant, peach blossom is put into container after cleaning, and is added 8-10 times the distilled water immersion measured 4-5 hours, and heating is boiled 3-4 hours, is extracted Immersion liquid；The 6-8 times of distilled water measured is added again, heating is boiled 2-3 hours, and immersion liquid is extracted；Finally add the 4-6 times of distillation measured Water, heating are boiled 1-2 hours, and immersion liquid is extracted；Merge immersion liquid three times, it is spare to obtain filtrate for filtering；

(2) smoothfruit ventilago root and stem, radix achyranthis bidentatae, Radix Angelicae Sinensis, radix rehmanniae preparata, Cortex Araliae Echinocaulis Radicis, heart seven, fiveleaf akebia root, lycopodium calvatum, thick leaf tree are cleaned and is put into appearance In device, the ethanol solution of the concentration 80% of 4 times of amounts is added, impregnates 1-2 hours, heating and refluxing extraction 3-4 hours, filtering obtained filtrate It is spare；

(3) net licorice tablet is taken, cooked honey and a little boiled water is added, it is slightly bored after mixing thoroughly, it sets in frying container, is fried with slow fire depth Yellow is taken out when tack-free, cools, and crushing is ground, and crosses 140 mesh dusting covers, obtains fine powder, spare；

(4) sprinkling of Rhizoma Chuanxiong piece yellow rice wine is taken uniformly, slightly bored, setting stir-fry to micro- coke in pot is degree, and taking-up cools, and crushing is ground, and crosses 140 Mesh dusting cover obtains fine powder, spare；

(5) radix paeoniae rubra piece is taken, yellow rice wine is added to mix thoroughly, it is slightly bored, after wine is sucked, sets in preheating frying container, heated with mild fire, fried extremely Yellowish, taking-up cools down, and weeds out clast, and crushing is ground, and crosses 140 mesh dusting covers, obtains fine powder, spare；

(6) it by step (1), step (2) resulting filtrate, is mixed with fine powder obtained in step (3), step (4), step (5), Add auxiliary material sucrose and dextrin to be uniformly mixed and particle is made, after dry, whole grain, is packaged into the instant particles as Chinese medicine of every bag of 6g.

The property of medicine of Chinese medicine is as follows:

Ficus lyrata: sweet in flavor；Micro-pungent；It is mild-natured.Dispelling wind and eliminating dampness；Removing toxicity for detumescence；Blood circulation.Main rheumatic arthralgia；Yellow subcutaneous ulcer；Malaria；Hundred Day cough；Alactation；Acute mastitis；Dysmenorrhea；Amenorrhoea；Carbuncle furuncle pain；Traumatic injury；Venomous snake bite." Fujian Chinese herbal medicine ": promoting blood circulation row Gas, channels sootheing and network vessel quickening.

Ramulus cinnamomi: acrid flavour；It is sweet；It is warm-natured.Enter bladder；The heart；Lung channel.Expelling cold and relieving exterior syndrome；Warming meridian；Activating YANG and prormoting functioning of QI.Cure mainly chill Exterior syndrome；Numbness and ache of cold dampness；Peripheral coldness；Amenorrhea and algomenorrhea；The agglomeration of wei lump in the abdomen；Thoracic obstruction；Palpitaition；Phlegm retention；Difficult urination." Changsha medicine solution " It carries: " entering liver man and promoting circulation of blood point, determine channels and collaterals and reach Rong Yu.Kind solution ailment said due to cold or exposure, most tune wood gas.The punching of turbid yin drops in the detrapping of sending up the lucid YANG It is inverse, the urgency contraction of relaxing muscles and tendons arteries and veins；The heap soil or fertilizer over and around the roots in sharp joint hinders.Enter liver and gallbladder and dissipate and suppress, pole relieves pain Chu, degrading the channel and to open numbness puckery, very go raw. Renal mass, more peace palpitation with fear can be stopped." modern medical studies have confirmed that ramulus cinnamomi can effectively expand blood vessel, promote sweating, contained cassia bark Aldehyde, natrium cinnamicum have antipyretic, analgesia, calm, anticonvulsant action, and furthermore there are also antibacterials, antiviral effect for ramulus cinnamomi.

Sharpleaf gambirplant root: bitter；It is puckery；It is cold in nature.Enter Liver Channel.Relaxing tendons and activating collaterals；Clearing heat for detumescence.Cure mainly arthragra；Hemiplegia；It is insane Epilepsy；Oedema；Injury from falling down." common Chinese herbal medicine handbook " carries: " controlling arthragra, rheumatic arthritis, sciatica." modern Medical research shows that sharpleaf gambirplant root containing indole alkaloids, there is significant anti-inflammatory, antibacterial action.

Rhizoma Atractylodis Macrocephalae: bitter；It is sweet；It is warm-natured.Returns spleen；Stomach meridian.Strengthening the spleen and replenishing qi；Eliminate dampness and have diuretic effect；Hidroschesis；Miscarriage prevention.Cure mainly deficiency-weakness of spleen-QI； Spiritlessness and weakness；Deficiency of food abdominal distension；Big loose stool is thin；Fluid retention stagnating in the interior；Difficult urination；Oedema；Phlegmatic vertigo；Arthritis with fixed pain caused by dampness is ached；Spontaneous perspiration due to deficiency of vital energy； Threatened abortion." this is through meeting original " carries: " art, raw to control wind-cold-dampness arthralgia with there is dehumidifying dry, the dissolving phlegm Li Shui of benefit, dead flesh convulsion subcutaneous ulcer dissipates waist navel Between blood and chong channel be disease, the function of urgency in inverse gas；Make it is ripe, have with middle tonifying Qi, slake thirst and help produce saliva, hidroschesis is except warm, into diet, miscarriage prevention it Effect." modern medical studies have confirmed that Rhizoma Atractylodis Macrocephalae has diuresis, hypoglycemic, strong, anticoagulation, antitumor, antibacterial, promotes hematopoiesis and egg The effect of white matter synthesis.

Smoothfruit ventilago root and stem: sweet in flavor；It is warm-natured.Return lung；The spleen channel.It fills blood；Strengthening the bones and muscles；Relax channels and collaterals.Cure mainly deficient qi and blood；Have through not It adjusts；Deficiency of blood menostasis；Rheumatalgia pain；Traumatic injury；Lumbar muscle strain." common Chinese herbal medicine handbook ": rich in nutrition, relaxing tendons and activating collaterals.It controls Deficiency of vital energy and blood, irregular menstruation, rheumatalgia, numb limb, traumatic injury.

Radix achyranthis bidentatae: bitter；Acid；It is mild-natured.Return liver；Kidney channel.Nourishing liver and kidney；Strengthening the bones and muscles；Blood circulation；It ignites downlink；Inducing diuresis for treating strangurtia. Cure mainly soreness of waist and knee joint；Flaccidity and weakness of the lower limbs；Amenorrhea due to stagnation of blood；Dysmenorrhea；Postpartum abdominal pain due to blood stasis；Levy lump in the abdomen；Placenta retension；Heat gonorrhea；Blood strangury；Bruise Damage；Carbuncle swells dislikes sore；Abscess of throat." drugization justice ": radix achyranthis bidentatae, it is sweet in flavor to mend, it can be held back with puckery, under simultaneous hardship is straight, enter kidney with it.Lid Kidney master closes hiding, and arresting seminal emission holds back blood, draws all medicine downlinks.It is solidifying to cure mainly puckery retention of urine pipe, gonorrhoea stem pain, stagnation of blood stasis, abdominal mass with then declaring for life Knot, married woman's menostasis, postpartum vomiting during early pregnancy take the function of its downlink of invigorating blood circulation.Wine system is ripe, mends, and cures mainly spasm of limbs, waist and knee skelagia, iliacus Flow pain, dry thirsty, the damp and hot flaccidity syndrome and arthralgia syndrome of malaria, it is old lose excessive, take tool to enrich blood the function of enriching yin.

Hirsute gonostegia herb with root: sweet in flavor；Slight bitter；It is cool in nature.It is clearing heat and detoxicating；Invigorating the spleen disperse accumulation；It is inducing diuresis and reducing edema；Dissipating stasis and stanching bleeding.Cure mainly acute mastitis；It is swollen Poison；Dysentery；Indigestion；Dyspeptic abdominalgia；Glucoside product；Leukorrhagia；Oedema；Difficult urination；Dysmenorrhea；Traumatic injury；Hemoptysis；It spits blood；Outside Hurt bleeding." civil common single medicine compilation " increasing blood, strengthening the spleen and stomach, Gu middle blood-nourishing.Fricassee is internal treatment of to have a weak heart.

Radix Angelicae Sinensis: sweet in flavor；It is pungent；It is warm-natured.Return liver, the heart, the spleen channel.Replenishing and activating blood；Menstruction regulating and pain relieving；Relax bowel and defecation.The deficiency of blood is cured mainly to wither It is yellow；Dizziness palpitaition；Asthenia cold abdominalgia；Rheumatic arthralgia；Injury from falling down；Ulcer sores." book on Chinese herbal medicine is just " carries: " its is sweet in flavor and weighs, therefore special energy Enrich blood, gas is light and pungent, therefore again can promoting circulation of blood, nutrition blood, tonifying Qi production of sperm, five viscera settling, strengthen body, beneficial mind, all tangible void can be supported The disease of damage, it is omni-benefiting." modern medical studies have confirmed that Radix Angelicae Sinensis has antibacterial, antiinflammation, it is acute to chronic articular rheumatism Breaking-out has apparent inhibiting effect.

Radix rehmanniae preparata: sweet in flavor；It is warm-natured；Return liver；Kidney channel.Enrich blood moist；Beneficial to spirit and marrow.Cure mainly blood deficiency chlorosis；Dizziness palpitaition；Liver kidney Yin deficiency；Soreness and weakness of waist and knees；Kidney deficiency characterized by dyspnea." collected statements on the herbal foundation " carries: " prolonged illness impairment of yin, the new blood that produces lose, in the required person of institute." modern medicine Research confirms, sitosterol, mannitol, Catalpol, rehmanin, carbohydrate, glucoside and multivitamin and minerals etc. are contained in radix rehmanniae preparata, Radix rehmanniae preparata have anti-lipid peroxidation, improve activities of antioxidant enzymes the effects of, and can lowering blood pressure and blood fat, inhibition thrombosis, Improve myocardial ischemia etc., radix rehmanniae preparata can be obviously promoted the proliferation and differentiation of marrow hemopoietic stem cells, there is apparent blood tonification effect.

Herba taxilli: bitter；It is sweet；It is mild-natured.Enter liver；Kidney channel.Nourishing liver and kidney；Strengthening the bones and muscles；Wind-damp dispelling；Miscarriage prevention.Cure mainly soreness of waist and knee joint； Muscles and bones impotence is weak；Limbs are hemiplegia；Rheumatic arthralgia；It has a dizzy spell；Threatened abortion, metrostaxis." book on Chinese herbal medicine is looked for the truth " carries: " edge Shen controls bone, Send out blood main, bitter man's kidney, it is strong that kidney must mend then muscles and bones, will not hemorrhoid and sour repeatly.It is sweet to enrich blood, blood must mend then hair filled by it is shady without Tangerine falls off.Therefore it is all in and pain in the loins, the sincere disease of muscles and bones, tire are fallen, outer and metal-inflicted wound, skin rheumatism." modern medical studies have confirmed that mulberry is posted There are decompression, anti-arrhythmia, increases coronary flow, improve coronary circulation, enhancing cardiac contractile force, reduce myocardial oxygen consumption, suppression Platelet aggregation processed, antithrombus formation improve many effects such as microcirculation, antitumor action, treatment hepatitis.

Pawpaw: sour；It is warm-natured.Enter liver；Lung；Kidney；The spleen channel.Relaxing tendons and activating collaterals；Stomach function regulating dampness elimination.Cure mainly rheumatic arthralgia, limbs acid Weight, muscle arteries and veins contraction, spasm of vomiting and diarrhoea, tinea pedis oedema." book on Chinese herbal medicine is just " carries: " treating waist-leg weakness, tinea pedis, indispensable, the stagnation of the circulation of vital energy energy of tying-in With qi exhaustion can consolidate.With the flat stomach of energy, therefore except inverse, choleraic myospasm of vomitting, phlegm is dropped, is dried, row water." modern medical studies have confirmed that pawpaw Containing carpaine, papain, renin, carrotene etc.；And rich in 17 kinds with upper amino acid and various nutrient elements, Have the effects that protect liver drop enzyme, anti-inflammatory antibacterial, reduction blood lipid, there are also prevent human carcinogen's substance nitrosamine from synthesizing.

Smallflower beggarticks herb: mildly bitter flavor；Micro-pungent；It is cool in nature.Clearing heat and promoting diuresis；Removing toxicity for detumescence；Promoting blood circulation and hemostasis.Cure mainly dysentery；Diarrhea edema； Cough；Asthma；Tonsillitis；Hemoptysis；Hematuria；Carbuncle and furuncle and pyogenic infections；Shingles zoster；Treating swelling and pain by traumatic injury；Traumatic hemorrhage." Quanzhou book on Chinese herbal medicine ": It is clearing heat and detoxicating, stasis eliminatings promoting blood circulation, regulating fluid apssage.Control ulcer furuncle, hot urination.

Cortex Araliae Echinocaulis Radicis: mildly bitter flavor；It is pungent；It is mild-natured.Dispelling wind and eliminating dampness；Blood-activating and qi-promoting；Removing toxicity for detumescence.Cure mainly rheumatic arthralgia；Bruise is swollen Bitterly；Fracture；Epigastric distending pain；Hernia；Metrorrhagia and metrostaxis；Osteomyelitis；Ulcer；Snake bite." common Chinese herbal folk proved recipe a collection of selected materials ": promoting blood circulation is broken The stasis of blood, wind-dispelling promoting the circulation of qi are clearing heat and detoxicating.Traumatic injury is controlled, is fractured, women's sepsis, osteomyelitis, ulcer, lyssodexis, rheumatic arthralgia.

Radix Glycyrrhizae: sweet in flavor；It is mild-natured.Return heart；Lung；Spleen；Stomach meridian.It invigorates the spleen and benefits qi；It is clearing heat and detoxicating；Expelling phlegm and arresting coughing；Relieving spasm to stop pain；It adjusts With all medicines.It cures mainly weakness of the spleen and the stomach；Fatigue and weakness；Shortness of breath and palpitation；Coughing with a lot of sputum；Stomach duct and abdomen four limbs contraction；Carbuncle sore tumefacting virus；Alleviate Drug toxicity.Compendium of Material Medica carries: " Radix Glycyrrhizae is monarch in all medicines.72 kinds of mammary calculus poison are controlled, draft is malicious by every means for solution 1,002, adjusts With it is active from medicine." modern medical studies have confirmed that Radix Glycyrrhizae has stronger detoxication, there are also antiulcer, anti-inflammatory, antispastic antibechic, Lowering blood pressure and blood fat, antitumaous effect are widely used in treatment sphagitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis Etc. diseases, additionally have anti-gastric-ulcer, gastritis effect.

Rhizoma Chuanxiong: acrid flavour；It is warm-natured.Return liver；Gallbladder；Pericardium channel.Promoting blood circulation；Promote breath and open depression；Wind-expelling pain-stopping.Zhu Zhi wei lump in the abdomen is swollen Block；Pain in chest and hypochondrium；Headache and dizziness；Wind-cold-dampness arthralgia；Traumatic injury；Ulcer sores." book on Chinese herbal medicine is just " carries: " dispersing wind and cold controls pain, broken stasis of blood It stores, promoting blood circulation, unhitch gas, by pain, apocenosis detumescence, by blood promoting menstruation." modern pharmacology research proves that heart is adjusted in Rhizoma Chuanxiong Convergent force expands blood vessel, improves microcirculation, has the function of being depressured, resist myocardial ischemia, anti-cerebral ischemia, can inhibit platelet aggregation Collection, antithrombus formation are adjusted uterine smooth muscle, calmness, analgesia, and have antibacterial action, can inhibit gram-negative bacteria, cause Characteristic of disease dermatophyte etc. has effects that enhance immune, antitumor, antireflection.

Heart seven: taste micro-sweet, it is cool in nature.It is clearing heat and detoxicating, warming and activating meridian, promoting blood circulation and hemostasis, synthetism.For traumatic injury, hemoptysis； Mazoitis, knife wound, exploration fracture, furuncle swelling toxin are controlled in external application.

Teasel root: bitter；It is pungent；Slightly warm in nature.Return liver；Kidney channel.Nourishing liver and kidney；Strengthening the bones and muscles；Adjust blood vessels；Continuous injured；Only metrorrhagia and metrostaxis.For Back ache；Podomere flaccidity syndrome and arthralgia syndrome；Fall and flutters wound；It damages disk and rolls over bone；Ulcer sore swells." Standards of Diagnosis and Treatment " carry: " sweet temperature is supporing yang, pungent to dissipate the stasis of blood, It has concurrently and tonifies the liver and kidney, strong bone strengthening, promoting blood circulation function." modern medical studies have confirmed that teasel root contains, there are many alkaloids and micro Element titanium plays the role of antivitamin E deficiency disease, plays the role of apocenosis to large carbuncle, hemostasis, analgesia, promotes regeneration.

Fiveleaf akebia root: bitter；It is mild-natured；Return liver；Kidney channel.Dispelling wind and removing obstruction in the meridians；Inducing diuresis for removing edema；The promoting flow of qi and blood circulation；Nourishing liver and kidney；Strengthening the bones and muscles. Cure mainly rheumatic arthralgia；Traumatic injury；Menostasis；Hernia；Testiclar gall；It is bored that stomach duct and abdomen is swollen；Difficult urination；Leukorrhagia；Worm snake bite." Zhejiang The civil common herbal medicine in river ": wind-expelling pain-stopping, the promoting flow of qi and blood circulation, diuresis removing toxic substances.

Radix paeoniae rubra: bitter；It is slightly cold.Return liver warp.Clearing heat and cooling blood；Promoting blood circulation.Cure mainly febrile virulent maculae；Hematemesis and epistaxis；Under intestines wind Blood；Red eye, swell pain；Carbuncle swells sore；Amenorrhoea；Dysmenorrhea；Collapse band stranguria with turbid discharge；The stagnant hypochondriac pain of the stasis of blood；The accumulation of hernia lump in the abdomen；Injury from falling down." legendary god of farming's book on Chinese herbal medicine Through " carry: " bitter is flat, main perverse trend abdominal pain, except blood-arthralgia, broken hard product fever and chills hernia lump in the abdomen, analgesic, raw Chuan Gu." modern medical studies have confirmed that Radix paeoniae rubra has anti-thrombosis function, antiplatelet aggregative activity, reducing blood lipid and anti arteriosclerosis effect, and to cardiovascular system There is certain influence, water-alcohol extraction has significant sedation and analgesic effect, can slightly improve the acidity of gastric juice, can be used for Improve appetite, digestive function and certain neuropathies.

Lycopodium calvatum: bitter；It is pungent；It is warm-natured.Enter Liver Channel.Dispelling wind and eliminating dampness；Clearing and activating the channels and collaterals；Swelling and pain relieving.Cure mainly lumbago, skelalgia of rheumatism； Arthralgia；Traumatic injury；Knife wound；Burn and scald." Hunan drug will " carries: " relaxing tendons and activating collaterals, invigorating qi and dredging collateral.Control pain in the loins, joint Bitterly, amenorrhoea." modern medicine study show lycopodium calvatum contain the alkaloids such as lycopodine, stick lycoclavanin alkali and terpenoid, Sterol and acids have cooling, hypotensive activity, can enhance heart contraction dynamics, excited smooth muscle, in addition there are bacteriostasis.

Thick leaf tree: acrid flavour；It is bitter；It is mild-natured.Blood-activating and qi-promoting；Swelling and pain relieving.Cure mainly gastral cavity pain；Traumatic injury；It is unknown swollen Poison.

Zlatostema involucratum Franch. Et savat: mildly bitter flavor；Cold nature.Return large intestine；Liver；The spleen channel.It is clearing heat and detoxicating；Dispelling wind and eliminating dampness；Inducing diuresis for removing edema；Promoting blood circulation stops Bitterly.Cure mainly dysentery；Hyperpyrexia and infantile convulsion；Yellow subcutaneous ulcer；Rheumatic arthralgia；Oedema；Stranguria；Menostasis；Sore swells；Mumps；Shingles zoster；Poisonous snake It bites；Traumatic injury；Fracture." Xinhua's book on Chinese herbal medicine outline ": herb, mildly bitter flavor are mild-natured.There is removing damp-heat, promoting blood circulation to remove blood stasis function is used In disease dysentery, rheumatalgia, jaundice, oedema, carbuncle and furuncle and pyogenic infections, fracture.

Pilose triumfetta root and leaf: sweet in flavor；Micro-pungent；It is warm-natured.Return liver warp.Blood-activating and qi-promoting；Eliminating stasis to subdue swelling.It has cured mainly through uncomfortable；Disease accumulates pain； Traumatic injury.

Peach blossom: bitter；It is mild-natured.Return heart；Liver；Large intestine channel.Li Shui；Activating microcirculation and removing stasis medicinal.Cure mainly oedema；Tinea pedis；Phlegm retention；Li Shui is logical Just；Stranguria dne to urolithiasis；Constipation；Amenorrhoea；It is demented；Sore rash." Bie Lu ": it is main to remove aqueous vapor, break urolithiasis, sharp stool and urine, lower three worms.

Compared with the prior art, the present invention has the following beneficial effects:

It is mutually auxiliary that the present invention selects the pharmacological property of medicinal material mutually to fit, and suits the remedy to the case, tonifies the liver and kidney, strengthening the spleen and replenishing qi, work of enriching blood for the cause of disease Blood, warming and activating meridian, blood-activating and qi-promoting, activating microcirculation and removing stasis medicinal, inducing diuresis and reducing edema, swelling and pain relieving, it is clearing heat and detoxicating the effect of, good absorption effect, treat Effect is significant, higher to the postoperative swelling cure rate of fracture of lower limb according to clinical verification.

Specific embodiment

Present invention is further elaborated in following combination specific embodiment.

Embodiment 1

The raw material of effective ingredient of the present invention forms and weight are as follows:

The processing step of process for preparing medicine of the present invention are as follows:

Usage and dosage: oral, 2 times a day, one bag each time, morning and evening sub-service, is taken after mixing it with water with boiled water within 1 hour after meal, and 7 days are 1 treatment Journey.

Embodiment 2

The process for preparing medicine processing step and usage and dosage of the present embodiment are same as Example 1.

Embodiment 3

Clinical data:

1, case selection

Fracture of lower limb 86 clinical observations of postoperative swelling patient that selection our hospital makes a definite diagnosis, patient are randomly divided into two groups.Treatment group 43 Example, wherein male 30, women 13, the age 15~52 years old, average age 35.2 years old, fracture site: femur 7, kneecap 9 Example, tibiofibula 11, anklebone 16.Control group 43, wherein male 32, women 11, the age 17~49 years old, average age 34.9 years old, fracture site: femur 11, kneecap 7, tibiofibula 8, anklebone 17.Two groups of patient's qualifications are almost the same, without aobvious Difference is write, is comparable.

2, treatment method: two groups of patients give the treatment means that lifting affected limb and limb function rehabilitation are taken exercise.

Treatment group patient takes drug of the present invention, takes orally, 2 times a day, one bag each time, morning and evening sub-service, and 1 hour after meal to open Mixing in water for oral taking, 7 days are 1 course for the treatment of, take 3 to 4 courses.

Control group gives the drugs such as conventional analgesia anti-inflammation medicine and controls according to the state of an illness of the postoperative swelling of the fracture of lower limb being diagnosed to be It treats, there is bleeding situation person to give haemostatic medicament, and give the physical therapy modalities that ice bag applies suffering limb.

3, efficacy determination:

(1) fully recover: lower extremity swelling and distension completely disappears.

(2) improve: swelling degree is substantially reduced.

(3) invalid: symptom is same to treat preceding no significant difference.

4, result

31 are cured in treatment group, are improved 8, invalid 4, cure rate 72.1%, total effective rate 90.7%.It is cured in control group It 22, improves 10, invalid 11, cure rate 51.2%, total effective rate 74.4%.

The above results show that the cure rate and total effective rate for the treatment of group are apparently higher than control group.

Typical case citing:

1, connect ××, it is male, 34 years old.The left leg fracture of tibia of the patient postoperative 5 months, shank swelling, joint stuffiness.Through taking this hair After 2 courses for the treatment of of the bright Chinese medicine, above-mentioned symptom is substantially reduced, follows the doctor's advice after continuing to take 1 course for the treatment of of Chinese medicine of the present invention, on It states symptom to completely disappear, fully recover.

2, neat ××, female, 28 years old.Patient femur's head fracture surgery 3 months, thigh swelling, edema of leg, through taking this hair After 4 courses for the treatment of of the bright Chinese medicine, above-mentioned symptom is completely disappeared, and has fully recovered.

3, Mr. Wang, male, 39 years old.Patient's anklebone fracture postoperative 80 days, ankle swelling, instep edema, through taking the present invention After 2 courses for the treatment of of the Chinese medicine, above-mentioned symptom is completely disappeared, and has fully recovered.

Blood overflows caused by exudation increases outside arteries and veins and between tissue after the postoperative swelling system damage of fracture of lower limb.<Jing Yue's complete work>cloud: It is all to control swollen person, it must first harness the river, since blood vessels are impaired, qi deficiency to blood stasis, hemostasis soaks unrestrained blood vessels with moisture and causes train of thought obstructed, therefore the deficiency of vital energy is wet The stasis of blood is main pathogenesis, the spleen being the foundation of acquired constitution, main four limbs, muscle, and spleen deficiency diet does not disappear, limbs fatigue, muscular atrophy, injured bones and muscles Slowly, the raw marrow of Shen controls bone store essential substances, growth, development, the reparation of bone have relied on the nourishing and promotion of the vital essence of kidney.Thus The present invention suits the remedy to the case according to the cause of disease, and smallflower beggarticks herb, hirsute gonostegia herb with root, Zlatostema involucratum Franch. Et savat can be clearing heat and detoxicating, inducing diuresis and reducing edema in side；Rhizoma Atractylodis Macrocephalae can in side Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect；Rhizoma Chuanxiong, radix paeoniae rubra, peach blossom can activating microcirculation and removing stasis medicinal in side；It is Ficus lyrata in side, pilose triumfetta root and leaf, thick leaf tree, red Aralia wood can blood gas, swelling and pain relieving；Ramulus cinnamomi, heart seven can warming and activating meridians, promoting blood circulation and hemostasis in side；It is herba taxilli in side, fiveleaf akebia root, continuous Breaking can nourishing liver and kidney, strengthening the bones and muscles；Smoothfruit ventilago root and stem, lycopodium calvatum, sharpleaf gambirplant root can relaxing tendons and activating collaterals in side；Radix Angelicae Sinensis, radix rehmanniae preparata can replenishing and activating bloods in side； In side radix achyranthis bidentatae, pawpaw can priming to lower limb, in side Radix Glycyrrhizae can coordinating the drug actions of a prescription, in side all medicines share can play altogether tonify the liver and kidney, invigorating the spleen QI invigorating, replenishing and activating blood, warming and activating meridian, blood-activating and qi-promoting, activating microcirculation and removing stasis medicinal, inducing diuresis and reducing edema, swelling and pain relieving, it is clearing heat and detoxicating the effect of, can Immunity of organisms is improved, human body fluid metabolism is adjusted, improves blood circulation, inhibit platelet aggregation, antithrombus formation, anti-inflammatory town Bitterly, eliminate swelling, good absorption effect is significant in efficacy, treating both manifestation and root cause of disease, according to clinical verification to the postoperative swelling cure rate of fracture of lower limb compared with It is high.

Claims

1. a kind of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb, which is characterized in that the original of the effective ingredient is made Material composition and parts by weight are as follows:

2. a kind of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb according to claim 1, which is characterized in that institute is made State the raw material composition and parts by weight of effective ingredient are as follows:

3. a kind of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb according to claim 1, which is characterized in that institute is made State the raw material composition and parts by weight of effective ingredient are as follows:

4. a kind of preparation side of instant particles as Chinese medicine for treating the postoperative swelling of fracture of lower limb according to any one of claim 1-3 Method, which is characterized in that comprise the following steps that: