CN106749168B - 一种制备2,4-二甲基四氢噻吩-3-酮的方法 - Google Patents
一种制备2,4-二甲基四氢噻吩-3-酮的方法 Download PDFInfo
- Publication number
- CN106749168B CN106749168B CN201611267800.5A CN201611267800A CN106749168B CN 106749168 B CN106749168 B CN 106749168B CN 201611267800 A CN201611267800 A CN 201611267800A CN 106749168 B CN106749168 B CN 106749168B
- Authority
- CN
- China
- Prior art keywords
- acid
- dimethyl
- organic solvent
- thia
- ketone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Description
Claims (27)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611267800.5A CN106749168B (zh) | 2016-12-31 | 2016-12-31 | 一种制备2,4-二甲基四氢噻吩-3-酮的方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611267800.5A CN106749168B (zh) | 2016-12-31 | 2016-12-31 | 一种制备2,4-二甲基四氢噻吩-3-酮的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106749168A CN106749168A (zh) | 2017-05-31 |
CN106749168B true CN106749168B (zh) | 2019-02-01 |
Family
ID=58952425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201611267800.5A Active CN106749168B (zh) | 2016-12-31 | 2016-12-31 | 一种制备2,4-二甲基四氢噻吩-3-酮的方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106749168B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108084148A (zh) * | 2017-11-15 | 2018-05-29 | 凯莱英医药集团(天津)股份有限公司 | 取代噻吩-3-酮类化合物的制备方法 |
CN108148041A (zh) * | 2017-11-15 | 2018-06-12 | 凯莱英医药集团(天津)股份有限公司 | 取代噻吩-3-酮类化合物的连续性合成方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN85106474A (zh) * | 1983-12-20 | 1987-04-29 | 山道士有限公司 | 氮-噻吩氯乙酰胺的制法 |
CN102229550A (zh) * | 2011-05-25 | 2011-11-02 | 原平市同利化工有限责任公司 | 一种3-巯基丙酸的制备方法 |
KR20120084675A (ko) * | 2011-01-20 | 2012-07-30 | 주식회사 케이오씨솔루션 | 3-메르캅토(메타)프로피온산의 제조방법 및 이를 이용한 메르캅토기를 갖는 (메타)카르본산 에스테르 화합물 |
US8258340B2 (en) * | 2008-03-12 | 2012-09-04 | Showa Denko K.K. | Method for producing β-mercapto carboxylic acids |
-
2016
- 2016-12-31 CN CN201611267800.5A patent/CN106749168B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN85106474A (zh) * | 1983-12-20 | 1987-04-29 | 山道士有限公司 | 氮-噻吩氯乙酰胺的制法 |
US8258340B2 (en) * | 2008-03-12 | 2012-09-04 | Showa Denko K.K. | Method for producing β-mercapto carboxylic acids |
KR20120084675A (ko) * | 2011-01-20 | 2012-07-30 | 주식회사 케이오씨솔루션 | 3-메르캅토(메타)프로피온산의 제조방법 및 이를 이용한 메르캅토기를 갖는 (메타)카르본산 에스테르 화합물 |
CN102229550A (zh) * | 2011-05-25 | 2011-11-02 | 原平市同利化工有限责任公司 | 一种3-巯基丙酸的制备方法 |
Non-Patent Citations (2)
Title |
---|
(S)-3-苯甲酰巯基-2-甲基丙酸的合成及表征;阮久勇 等;《化工进展》;20121231;第31卷(第5期);第1130-1134页 |
Derivatives of 2-mercaptoisobutyric acid;Fredga, Arne等;《Arkiv foer Kemi, Mineralogi och Geologi》;19431231;第16卷(第8期);STN摘要 |
Also Published As
Publication number | Publication date |
---|---|
CN106749168A (zh) | 2017-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105601538B (zh) | 一种氰氟草酯的制备方法 | |
CN106749168B (zh) | 一种制备2,4-二甲基四氢噻吩-3-酮的方法 | |
CN106977572B (zh) | 一种以猪去氧胆酸为原料合成石胆酸的方法 | |
CN105566158B (zh) | 一种氰氟草酯的制备方法 | |
CN108218851A (zh) | 一种改进制备苯唑草酮的方法 | |
CN104803875A (zh) | 一种s-异丙甲草胺的合成方法 | |
CN105384707A (zh) | 一种α-氨基苯乙酮类光引发剂的制备方法 | |
CN103420834B (zh) | 一种环保清洁的丙二酸二甲酯制备方法 | |
CN103539704A (zh) | 一种敌草隆的制备方法 | |
CN103172561B (zh) | 一锅法合成氟草烟仲辛酯的方法 | |
CN103254146B (zh) | 苯嗪草酮的制备方法 | |
CN103420833B (zh) | 一种对甲苯磺酸催化的丙二酸二甲酯合成方法 | |
CN111170846B (zh) | 一种制备3,3-二甲基-2-氧-丁酸的方法 | |
CN104355988B (zh) | 一种2-(4-溴甲基苯基)丙酸的合成方法 | |
CN110330417A (zh) | 2,5-二羟基苯甲醛的制备方法 | |
CN112047878B (zh) | 4-溴-6-氯吡啶-2-羧酸的制备方法 | |
CN113277984B (zh) | 一种制备3,6-二氯哒嗪-4-醇的方法 | |
CN105085255B (zh) | 一种咪唑啉酮类除草剂中间体2‑烷氧基‑3‑氧代‑丁二酸二酯的合成工艺 | |
CN106397395A (zh) | 一种制备2,4‑二甲基四氢噻吩‑3‑酮的方法 | |
CN107325060A (zh) | 一种结晶形态的Lesinurad中间体及其制备方法 | |
CN105175250B (zh) | 一种合成环丙贝特的新方法 | |
CN114133356B (zh) | 一种哒嗪类化合物及其应用 | |
CN110066268A (zh) | 3-氨基-2,4-二甲基噻吩的制备方法 | |
CN104557763A (zh) | 一种2-异丙基-4-(甲基氨基甲基)噻唑的合成方法 | |
CN108285433A (zh) | 一种合成马来酰肼的方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP02 | Change in the address of a patent holder |
Address after: 102206 6th floor, building 4, hospital 9, medical Road, Life Science Park, Changping District, Beijing Patentee after: Purpana (Beijing) Technologies Co.,Ltd. Address before: 102206, No. 9, building 4, 4 Life Garden Road, Changping District science and Technology Park, Beijing, 401 Patentee before: Purpana (Beijing) Technologies Co.,Ltd. |
|
CP02 | Change in the address of a patent holder | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A method for preparing 2,4-dimethyltetrahydrothiophene-3-one Effective date of registration: 20210702 Granted publication date: 20190201 Pledgee: Agricultural Development Bank of China Baiyin branch business department Pledgor: Purpana (Beijing) Technologies Co.,Ltd. Registration number: Y2021990000573 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |