CN106730010A - 去细胞神经水凝胶用于制备周围神经损伤修复组合物的用途 - Google Patents
去细胞神经水凝胶用于制备周围神经损伤修复组合物的用途 Download PDFInfo
- Publication number
- CN106730010A CN106730010A CN201710001647.XA CN201710001647A CN106730010A CN 106730010 A CN106730010 A CN 106730010A CN 201710001647 A CN201710001647 A CN 201710001647A CN 106730010 A CN106730010 A CN 106730010A
- Authority
- CN
- China
- Prior art keywords
- nerve
- hydrogel
- acellular
- purposes
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3675—Nerve tissue, e.g. brain, spinal cord, nerves, dura mater
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710001647.XA CN106730010A (zh) | 2017-01-03 | 2017-01-03 | 去细胞神经水凝胶用于制备周围神经损伤修复组合物的用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710001647.XA CN106730010A (zh) | 2017-01-03 | 2017-01-03 | 去细胞神经水凝胶用于制备周围神经损伤修复组合物的用途 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106730010A true CN106730010A (zh) | 2017-05-31 |
Family
ID=58952209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710001647.XA Pending CN106730010A (zh) | 2017-01-03 | 2017-01-03 | 去细胞神经水凝胶用于制备周围神经损伤修复组合物的用途 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106730010A (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108853583A (zh) * | 2018-06-22 | 2018-11-23 | 中山大学附属第医院 | 一种基于3d打印的周围神经支架及其制备方法 |
CN108939165A (zh) * | 2018-06-22 | 2018-12-07 | 中山大学附属第医院 | 一种周围神经支架及其制备方法 |
CN111035811A (zh) * | 2019-12-20 | 2020-04-21 | 中山大学 | 一种双层神经导管及制备方法 |
CN111068118A (zh) * | 2019-12-20 | 2020-04-28 | 中山大学 | 一种人工神经移植物及制备方法 |
CN112755250A (zh) * | 2020-12-31 | 2021-05-07 | 西安交通大学口腔医院 | 一种组织工程化周围神经组织及其制备方法 |
CN114504683A (zh) * | 2022-02-23 | 2022-05-17 | 中山大学 | 一种可注射生物活性复合导电水凝胶及其制备方法与应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102114268A (zh) * | 2010-01-05 | 2011-07-06 | 卢世璧 | 一种组织工程神经支架及其制备方法和应用 |
CN104740685A (zh) * | 2015-04-16 | 2015-07-01 | 烟台隽秀生物科技有限公司 | 一种神经修复膜及其制备方法 |
CN104971380A (zh) * | 2014-04-11 | 2015-10-14 | 烟台隽秀生物科技有限公司 | 一种脱细胞基质修复凝胶及其制备新方法 |
CN105169483A (zh) * | 2015-10-20 | 2015-12-23 | 中山大学 | 一种脱细胞基质凝胶的制备方法及其脱细胞基质凝胶 |
CN105879119A (zh) * | 2016-06-06 | 2016-08-24 | 东华大学 | 一种复合脱细胞基质水凝胶及其制备方法 |
CN106139250A (zh) * | 2016-07-29 | 2016-11-23 | 烟台正海生物科技股份有限公司 | 一种脱细胞异种神经移植物及其制备方法 |
-
2017
- 2017-01-03 CN CN201710001647.XA patent/CN106730010A/zh active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102114268A (zh) * | 2010-01-05 | 2011-07-06 | 卢世璧 | 一种组织工程神经支架及其制备方法和应用 |
CN104971380A (zh) * | 2014-04-11 | 2015-10-14 | 烟台隽秀生物科技有限公司 | 一种脱细胞基质修复凝胶及其制备新方法 |
CN104740685A (zh) * | 2015-04-16 | 2015-07-01 | 烟台隽秀生物科技有限公司 | 一种神经修复膜及其制备方法 |
CN105169483A (zh) * | 2015-10-20 | 2015-12-23 | 中山大学 | 一种脱细胞基质凝胶的制备方法及其脱细胞基质凝胶 |
CN105879119A (zh) * | 2016-06-06 | 2016-08-24 | 东华大学 | 一种复合脱细胞基质水凝胶及其制备方法 |
CN106139250A (zh) * | 2016-07-29 | 2016-11-23 | 烟台正海生物科技股份有限公司 | 一种脱细胞异种神经移植物及其制备方法 |
Non-Patent Citations (3)
Title |
---|
CHRISTOPHER J.MEDBERRY ET AL: "Hydrogels derived from central nervous system extracellular matrix", 《BIOMATERIALS》 * |
张弛等: "脊髓损伤修复再生支架材料研究进展", 《高分子通报》 * |
朱庆棠等: "去细胞组织工程化神经支架的制备与形态学研究", 《中华显微外科杂志》 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108853583A (zh) * | 2018-06-22 | 2018-11-23 | 中山大学附属第医院 | 一种基于3d打印的周围神经支架及其制备方法 |
CN108939165A (zh) * | 2018-06-22 | 2018-12-07 | 中山大学附属第医院 | 一种周围神经支架及其制备方法 |
CN111035811A (zh) * | 2019-12-20 | 2020-04-21 | 中山大学 | 一种双层神经导管及制备方法 |
CN111068118A (zh) * | 2019-12-20 | 2020-04-28 | 中山大学 | 一种人工神经移植物及制备方法 |
CN111068118B (zh) * | 2019-12-20 | 2021-12-07 | 中山大学 | 一种人工神经移植物及制备方法 |
CN112755250A (zh) * | 2020-12-31 | 2021-05-07 | 西安交通大学口腔医院 | 一种组织工程化周围神经组织及其制备方法 |
CN114504683A (zh) * | 2022-02-23 | 2022-05-17 | 中山大学 | 一种可注射生物活性复合导电水凝胶及其制备方法与应用 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106730010A (zh) | 去细胞神经水凝胶用于制备周围神经损伤修复组合物的用途 | |
Kim et al. | Fabrication of transparent hemispherical 3D nanofibrous scaffolds with radially aligned patterns via a novel electrospinning method | |
Salehi et al. | Alginate/chitosan hydrogel containing olfactory ectomesenchymal stem cells for sciatic nerve tissue engineering | |
Zheng et al. | The influence of Gelatin/PCL ratio and 3-D construct shape of electrospun membranes on cartilage regeneration | |
Bhaarathy et al. | Biologically improved nanofibrous scaffolds for cardiac tissue engineering | |
KR101202839B1 (ko) | 관절연골 재생용 지지체 및 이의 제조방법 | |
CN105920672A (zh) | 一种可促进外周神经组织快速修复的导电平行纤维膜及其制备方法 | |
Kriebel et al. | Three‐dimensional configuration of orientated fibers as guidance structures for cell migration and axonal growth | |
EP2197504B1 (en) | Biomaterial scaffolds for controlled tissue growth | |
CN109475606A (zh) | 从电纺脱细胞的细胞外基质制造的支架 | |
Teplenin et al. | Functional analysis of the engineered cardiac tissue grown on recombinant spidroin fiber meshes | |
US20180105795A1 (en) | Method for preparation of extracellular matrix-modified decellularized nerve scaffold and use thereof | |
CN107510862A (zh) | 担载梯度浓度生物活性分子的有序纤维支架、制法及应用 | |
Wang et al. | The spatial arrangement of cells in a 3D-printed biomimetic spinal cord promotes directional differentiation and repairs the motor function after spinal cord injury | |
Su et al. | Nanofiber containing carbon nanotubes enhanced PC12 cell proliferation and neuritogenesis by electrical stimulation | |
CN105143442A (zh) | 用于体外干细胞增殖和组织再生的生长基质 | |
CN106924817B (zh) | 一种超薄载体细胞片及其制备方法 | |
CN114606189A (zh) | 一种促进神经干细胞增殖分化的脱细胞脊髓- GelMA水凝胶复合材料支架 | |
CN109793934B (zh) | 一种组织工程化心肌补片及其制备和应用 | |
Qi et al. | Experimental study on repairing peripheral nerve defects with novel bionic tissue engineering | |
Ashraf et al. | Recent trends in peripheral nervous regeneration using 3D biomaterials | |
WO2024037293A1 (zh) | 一种修复周围神经损伤的细胞基质神经移植物及其制备方法 | |
Tan et al. | Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes | |
US20210063374A1 (en) | Abnormal cardiac rhythm myocardial model and method for producing same, agent for forming abnormal cardiac rhythm myocardial model, and method for evaluating drug efficacy of heart disease therapeutic | |
Gordián-Vélez et al. | Dopaminergic axon tracts within a hyaluronic acid hydrogel encasement for implantation to restore the nigrostriatal pathway |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20180223 Address after: 510000 Guangzhou City, Guangzhou, Guangdong, Guangzhou international bio Island spiral three road 6, seventh layer 701 unit Applicant after: GUANGZHOU XINCHENG BIOTECHNOLOGY CO., LTD. Applicant after: Sun Yat-sen University Applicant after: No.1 Hospital Affiliated to Zhongshan Univ. Address before: 510000 Guangzhou City, Guangzhou, Guangdong, Guangzhou international bio Island spiral three road 6, seventh layer 701 unit Applicant before: GUANGZHOU XINCHENG BIOTECHNOLOGY CO., LTD. |
|
TA01 | Transfer of patent application right | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170531 |
|
WD01 | Invention patent application deemed withdrawn after publication |