CN106728373A - Poria cocos glossy ganoderma and honey oral liquid - Google Patents
Poria cocos glossy ganoderma and honey oral liquid Download PDFInfo
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- CN106728373A CN106728373A CN201611178783.8A CN201611178783A CN106728373A CN 106728373 A CN106728373 A CN 106728373A CN 201611178783 A CN201611178783 A CN 201611178783A CN 106728373 A CN106728373 A CN 106728373A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
Poria cocos glossy ganoderma and honey oral liquid, including following mass parts raw material：Poria cocos：200 ~ 400 parts, honey：200 ~ 400 parts, date：100 ~ 200 parts, matrimony vine：50 ~ 80 parts, 15 ~ 20 parts of ganoderma lucidum, 50 ~ 75 parts of peppermint, when it is prepared, honey is first carried out into removal of impurities concentration, and bubbled open under the conditions of warm water, simultaneously, the peppermint slag that peppermint oil will be extracted merges with Poria cocos, date, honey and is decocted twice, carry out merging decocting liquid twice after separation of solid and liquid and cooling down respectively, peppermint is carried out into peppermint oil extract again, and in incorporating absolute ethyl alcohol, and ganoderma lucidum is stood with being sieved after colloid mill ultramicro grinding and being added in absolute ethyl alcohol, then three kinds of liquid are merged and finished product is obtained after being concentrated under reduced pressure.The present invention can effectively improve body immunity, promote metabolism, and the effects such as with antifatigue and anti-aging.
Description
Technical field
The present invention relates to oral traditional Chinese medicine preparation field, and in particular to a kind of Poria cocos glossy ganoderma and honey oral liquid.
Background technology
Poria cocos, alias cloud Siberian cocklebur, Fu spirits, loose Poria cocos, pine potato etc., are the Polyporaceae plants for colonizing in pine tree root, are one
Precious medicine-food two-purpose bacterium is planted, is exactly since ancient times the health food of integration of drinking and medicinal herbs, the concern of people is constantly subjected to, rich in Poria cocos
The multiple efficacies composition such as polysaccharide, with strengthening the spleen and stomach, inducing diuresis for removing edema, reducing blood lipid, regulation immunity of organism, anti-aging, antitumor, anti-prominent
The functions such as change；Ancients' Poria cocos is called " god's medicine when four ", because its effect is widely, regardless of the four seasons, it is matched somebody with somebody with various medicines
5, no matter cold, temperature, wind, wet all diseases, can play its unique effects.
Ganoderma lucidum is precious also known as Lin Zhongling, fine jade, is the fructification of On Polyporaceae ganoderma lucidum, and a kind of treasure is considered to since ancient times
Expensive medicine-food two-purpose bacterium.Its master contains amino acid, polypeptide, protein, fungal lysozyme, and carbohydrate（Reduced sugar and polysaccharide）, wheat
Angle sterol, triterpenes, coumarin glucoside, volatile oil, stearic acid, benzoic acid, alkaloid, vitamin B2And C etc.；Spore also contains sweet dew
Alcohol, trehalose, have functions that invigorating qi for tranquilization, it is relieving cough and asthma, promote longevity.By a large amount of clinical researches, ganoderma lucidum declines to nerve
Weak, hyperlipidemia, coronary disease and angina pectoris, arrhythmia cordis, Keshan disease, plateau uncomfortable diseases, hepatitis, Hemorrhagic fever, indigestion, tracheae
Inflammation etc. is had nothing in common with each other the curative effect of degree.
Honey is all employed as a kind of nutritious non-staple food in many prescriptions, among the people to use honeybee extensively very early
Honey treats many diseases, and thinks that it is the treasure promoted longevity.In recent years, China's medical and health worker was by repeatedly
Clinical trial certificate, honey is to heart disease, hepatopathy, hypertension, tuberculosis, illness in eye, diabetes, dysentery, constipation, anaemia, stomach
And the disease such as duodenal ulcer, arthritis, the nervous system disease, skin disease, scald, frostbite has different degrees of curative effect.
At present, it is mainly based on simple powder, it is necessary to by human body body for the application of the medicine of said components
Digestion after can be absorbed so that its these preparation bioavailability is relatively low, in-convenience in use, work slow, and if adopting
Oral liquid formulations are prepared with traditional water extraction, its recovery rate is only 25% ~ 32%, the need for not reaching industrial production at all, caused
The serious waste of material.
The content of the invention
Technical problem solved by the invention is to provide a kind of Poria cocos glossy ganoderma and honey oral liquid, is carried on the back with solving above-mentioned technology
Defect in scape.
Technical problem solved by the invention is realized using following technical scheme：
Poria cocos glossy ganoderma and honey oral liquid, including following mass parts raw material：
Poria cocos：200 ~ 400 parts, honey：200 ~ 400 parts, date：100 ~ 200 parts, matrimony vine：50 ~ 80 parts, ganoderma lucidum：15 ~ 20 parts, it is thin
Lotus：50 ~ 75 parts.
Its preferred mass part is：Poria cocos：300 parts, honey：300 parts, date：160 parts, matrimony vine：60 parts, ganoderma lucidum：18 parts,
Peppermint：60 parts.
Its specific preparation method is as follows：
1）Honey carries out removal of impurities is filtered, is concentrated under conditions of 37 ~ 45 DEG C and 0.1~0.12MPa of vacuum, in making honey
Moisture is less than 19.5%, then adds 37 ~ 45 DEG C of warm water by added water per the 100g amount of 1000 ~ 1200ml of the honey after concentration,
20 ~ 40min of insulation.
2）The peppermint for taking above-mentioned mass parts extracts peppermint oil, and the peppermint oil that will be extracted is in the ratio per 5 ~ 8ml of 100g peppermints
It is dissolved in absolute ethyl alcohol, ganoderma lucidum is then carried out into ultramicro grinding with colloid mill, 200 ~ 300 mesh sieves is crossed, then by levigate powder one
And in adding absolute ethyl alcohol, 1.5 ~ 2h is stood under the conditions of 70 ~ 85 DEG C.
3）Peppermint slag, Poria cocos, date and the matrimony vine that peppermint oil will be extracted merge, and are added by every 500g medicines gross mass
The ratio of 5000 ~ 6000ml adds water, and small fire is turned after being then boiled by fire and decocts 2 ~ 3h, carries out separation of solid and liquid, then adds
2000 ~ 3000ml water, turns small fire and decocts 1 ~ 2h after being boiled by fire, carry out merging decocting liquid twice after separation of solid and liquid, filters simultaneously cold
But to room temperature.
4）Merge three kinds of liquid, it is concentrated under reduced pressure to make relative density of the liquid at 20 DEG C be 1.05 ~ 1.12, get product.
As the further improvement of above-mentioned steps：
The honey is preferably using the one or any ratio in sophorae honey, cercis nectar, honey of lungan flowers, Mel Jujubae, matrimony vine honey
Mixing.
The peppermint oil uses extraction by steam distillation.
The step 4) in amalgamation liquid carry out it is concentrated under reduced pressure before, Sodium Benzoate can be added and enter to exercise as preservative
With.
To step 4) obtained by finished product can just must carry out after autoclaving it is filling.
Beneficial effect：Poria cocos glossy ganoderma and honey oral liquid of the present invention, mediation supplement is carried out by adding honey in Poria cocos, is matched somebody with somebody
Closing the various active principles in ganoderma lucidum can effectively improve body immunity, promote metabolism, while also having antifatigue and anti-
The effects such as aging.
Specific embodiment
In order that technological means, creation characteristic, reached purpose and effect that the present invention is realized are easy to understand, tie below
Specific embodiment is closed, the present invention is expanded on further.
Embodiment one：
Include the raw material of following components in this embodiment：
Poria cocos：240g, sophorae honey：220g, date：130g, matrimony vine：50g, ganoderma lucidum：15 parts, peppermint：50g.
Sophorae honey is first carried out into removal of impurities is filtered during preparation, is concentrated under conditions of 37 DEG C and vacuum 0.1MPa, made
Moisture is less than 19.5% in honey, the amount plus 42 DEG C of warm water of 1000ml that the honey after concentration is added water per 100g, insulation
20min。
By peppermint extraction by steam distillation peppermint oil, then the peppermint oil of extraction is added to the absolute ethyl alcohol of 4ml
In；Ganoderma lucidum is carried out into ultramicro grinding with colloid mill simultaneously, 300 mesh sieves are crossed, then levigate powder is added dissolved with peppermint oil in the lump
Absolute ethyl alcohol in, stand 1.5h under the conditions of 82 DEG C.
The peppermint slag and Poria cocos, date and matrimony vine that peppermint oil will be extracted merge and the water of 5500ml adds container in the lump
In, big fire heating is carried out to container, small fire is turned after boiling and decocts 130min, first time separation of solid and liquid is then carried out, by solid-liquid point
Residue after adds 2400ml water, small fire is turned after being boiled by fire and decocts 2h, then carries out second separation of solid and liquid, merges solid twice
The liquid that liquid is separate, filters out the impurity in liquid, is subsequently cooled to room temperature.
Then three kinds of liquid are mixed, being concentrated under reduced pressure after stirring makes relative density of the liquid at 20 DEG C be 1.08,
Then it is filling after autoclaving.
Embodiment two：
Include the raw material of following components in this embodiment：
Poria cocos：300 parts, matrimony vine honey：300g, date：160g, matrimony vine：60g, ganoderma lucidum：18 parts, peppermint 60g.
Sophorae honey is first carried out into removal of impurities is filtered during preparation, is concentrated under conditions of 42 DEG C and vacuum 0.12MPa, made
Moisture is less than 19.5% in honey, the amount plus 438 DEG C of warm water of 1100ml that the honey after concentration is added water per 100g, insulation
35min。
By peppermint extraction by steam distillation peppermint oil, then the peppermint oil of extraction is added to the absolute ethyl alcohol of 5ml
In；Ganoderma lucidum is carried out into ultramicro grinding with colloid mill simultaneously, 500 mesh sieves are crossed, then levigate powder is added dissolved with peppermint oil in the lump
Absolute ethyl alcohol in, stand 2h under the conditions of 85 DEG C.
The peppermint slag and Poria cocos, date and matrimony vine that peppermint oil will be extracted merge and the water of 6500ml adds container in the lump
In, big fire heating is carried out to container, small fire is turned after boiling and decocts 130min, first time separation of solid and liquid is then carried out, by solid-liquid point
Residue after adds 3200ml water, small fire is turned after being boiled by fire and decocts 2h, then carries out second separation of solid and liquid, merges solid twice
The liquid that liquid is separate, filters out the impurity in liquid, is subsequently cooled to room temperature.
Then three kinds of liquid are mixed, is stirring evenly and then adding into 5g Sodium Benzoates as preservative, being then concentrated under reduced pressure makes
Relative density of the liquid at 20 DEG C is 1.10, then filling after autoclaving.
General principle of the invention, principal character and advantages of the present invention has been shown and described above.The technology of the industry
Personnel it should be appreciated that the present invention is not limited to the above embodiments, simply explanation described in above-described embodiment and specification this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appending claims and its
Equivalent thereof.
Claims (6)
1. Poria cocos glossy ganoderma and honey oral liquid, it is characterised in that the raw material including following mass parts：Poria cocos：200 ~ 400 parts, honey：
200 ~ 400 parts, date：100 ~ 200 parts, matrimony vine：50 ~ 80 parts, 15 ~ 20 parts of ganoderma lucidum, 50 ~ 75 parts of peppermint.
2. Poria cocos glossy ganoderma and honey oral liquid according to claim 1, it is characterised in that the raw material including following mass parts：
Poria cocos：300 parts, honey：300 parts, date：160 parts, matrimony vine：60 parts, 18 parts of ganoderma lucidum, 60 parts of peppermint.
3. Poria cocos glossy ganoderma and honey oral liquid according to claim 1 and 2, it is characterised in that the honey is sophorae honey, purple
The mixing of the one or any ratio in chaste tree nectar, honey of lungan flowers, Mel Jujubae, matrimony vine honey.
4. a kind of preparation method of Poria cocos glossy ganoderma and honey oral liquid, it is characterised in that using each described in claim 1 or 2
The raw material of component prepares Poria cocos glossy ganoderma and honey oral liquid, and its specific preparation method is as follows：
1）Honey carries out removal of impurities is filtered, is concentrated under conditions of 37 ~ 45 DEG C and 0.1~0.12MPa of vacuum, in making honey
Moisture is less than 19.5%, then adds 37 ~ 45 DEG C of warm water by added water per the 100g amount of 1000 ~ 1200ml of the honey after concentration,
20 ~ 40min of insulation；
2）The peppermint for taking above-mentioned mass parts extracts peppermint oil, and the peppermint oil for extracting is dissolved in the ratio per 5 ~ 8ml of 100g peppermints
In absolute ethyl alcohol, ganoderma lucidum is then carried out into ultramicro grinding with colloid mill, cross 200 ~ 300 mesh sieves, then add levigate powder in the lump
Enter in absolute ethyl alcohol, 1.5 ~ 2h is stood under the conditions of 70 ~ 85 DEG C；
3）Peppermint slag, Poria cocos, date and the matrimony vine that peppermint oil will be extracted merge, and 5000 are added by every 500g medicines gross mass
The ratio of ~ 6000ml adds water, and small fire is turned after being then boiled by fire and decocts 2 ~ 3h, carries out separation of solid and liquid, then add 2000 ~
3000ml water, turns small fire and decocts 1 ~ 2h after being boiled by fire, carry out merging decocting liquid twice after separation of solid and liquid, filters and be cooled to room
Temperature；
4）Merge three kinds of liquid, being concentrated under reduced pressure after being well mixed makes relative density of the liquid at 20 DEG C be 1.05 ~ 1.12, obtains final product
Finished product.
5. preparation method according to claim 3, it is characterised in that the step 1）In peppermint oil using vapor steam
Evaporate method extraction.
6. preparation method according to claim 3, it is characterised in that the step 4) in amalgamation liquid be concentrated under reduced pressure
Addition Sodium Benzoate is used as preservative before.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611178783.8A CN106728373A (en) | 2016-12-19 | 2016-12-19 | Poria cocos glossy ganoderma and honey oral liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611178783.8A CN106728373A (en) | 2016-12-19 | 2016-12-19 | Poria cocos glossy ganoderma and honey oral liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106728373A true CN106728373A (en) | 2017-05-31 |
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ID=58890389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611178783.8A Withdrawn CN106728373A (en) | 2016-12-19 | 2016-12-19 | Poria cocos glossy ganoderma and honey oral liquid |
Country Status (1)
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107913292A (en) * | 2017-11-16 | 2018-04-17 | 徐州市卡农生物科技有限公司 | A kind of Ganoderma Sinense oral liquid |
| CN112772916A (en) * | 2021-01-28 | 2021-05-11 | 练国瑚 | Formula and preparation method of lucid ganoderma oral liquid |
-
2016
- 2016-12-19 CN CN201611178783.8A patent/CN106728373A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107913292A (en) * | 2017-11-16 | 2018-04-17 | 徐州市卡农生物科技有限公司 | A kind of Ganoderma Sinense oral liquid |
| CN112772916A (en) * | 2021-01-28 | 2021-05-11 | 练国瑚 | Formula and preparation method of lucid ganoderma oral liquid |
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Application publication date: 20170531 |