CN106728338A - A kind of black hair Chinese medicine composition, its preparation method and its preparation for nourishing scalp and hair follicle - Google Patents
A kind of black hair Chinese medicine composition, its preparation method and its preparation for nourishing scalp and hair follicle Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention provides a kind of black hair Chinese medicine composition for nourishing scalp and hair follicle, it is obtained by the raw material including following components：The RADIX POLYGONI MULTIFLORI PREPARATA of 1 100 weight portions；The cacumen biotae of 1 80 weight portions；The seed of Oriental arborvitae of 1 60 weight portions；The SEMEN PINI KORAIENSIS of 1 60 weight portions；The walnut kernel of 1 80 weight portions；The glutinous rehmannia of 1 70 weight portions；The Radix Angelicae Sinensis of 1 70 weight portions；The Radix Astragali of 1 100 weight portions.In addition, present invention also offers the preparation method and its preparation of above-mentioned black hair Chinese medicine composition.The present invention is by rational compatibility application and synergy between each Chinese medicine so that the composition of extraction can nourish scalp and hair follicle, with good black hair effect.Inventive formulation is unique, and medicinal material used is pure plant Chinese medicine, any chemical composition additive is not added with the product being made, and safe and nontoxic, effect is good.Further, the present invention prepares product using oxygenated water first, can preferably play nourishing, black hair effect.
Description
Technical field
The present invention relates to black hair technical field, more particularly to a kind of black hair Chinese medicine composition for nourishing scalp and hair follicle, its
Preparation method and its preparation.
Background technology
White hair finger hair is all or part of to bleach, and can be divided into congenital and two kinds of posteriority.Wherein, congenital white hair is often
There is family history, caused by inherent cause；Posteriority white hair has the one's early years property white hair that senile white hair and teenager, a middle-aged person are suffered from
Two kinds.The generation of white hair is due to the reason that melanin granule in hair medullary substance and cortex is reduced or filled a vacancy by air；Normal
In the case of, there is abundant blood vessel in papilla, the nutrition of abundance is provided for papilla, ball top portion, melanin granule is just smoothly closed
Into.When melanin granule papilla, ball top portion formation occur obstacle, although or formed because of certain factor, it is impossible to transport
To in hair, so that when the melanin granule of medulla of hair, cortical section is reduced, disappeared, white hair just occurs.
In modern metropolitan cities high efficiency, allegro Working Life, the white hair phenomenon of people increasingly increases.And shiny black head
Hair is one of mark of youth and health, the purpose vigorous and graceful in order to reach the hairs such as black hair, and in the market has many hair black hairs of educating to produce
Product.At present, the hair blackening product of in the market is generally chemical products, if long-term use, toxic and side effect is obvious；And existing Chinese medicine crow
The overall curative effect for sending out product is not high, is subject to certain restrictions in use.
The content of the invention
In view of this, the application provide a kind of black hair Chinese medicine composition for nourishing scalp and hair follicle, its preparation method and its
Preparation, the black hair Chinese medicine composition that the present invention is provided can nourish scalp and hair follicle, hair be bleached with good therapeutic effect,
And it is safe and nontoxic.
The present invention provides a kind of black hair Chinese medicine composition for nourishing scalp and hair follicle, by the raw material system including following components
：
The RADIX POLYGONI MULTIFLORI PREPARATA of 1-100 weight portions；
The cacumen biotae of 1-80 weight portions；
The seed of Oriental arborvitae of 1-60 weight portions；
The SEMEN PINI KORAIENSIS of 1-60 weight portions；
The walnut kernel of 1-80 weight portions；
The glutinous rehmannia of 1-70 weight portions；
The Radix Angelicae Sinensis of 1-70 weight portions；
The Radix Astragali of 1-100 weight portions.
Preferably, the raw material also includes oxygenated water.
The present invention provides the preparation method of black hair Chinese medicine composition mentioned above, comprises the following steps：
After the prepared slices of Chinese crude drugs of each component are mixed, extracted as solvent using alcohol and/or water, obtained black hair Chinese medicine group
Compound.
Preferably, the solvent is liquor made from sorghum that alcoholic strength is 60~65%.
Preferably, after the prepared slices of Chinese crude drugs of each component are mixed, plus 6~liquor made from sorghum of 10 times of volumes soaks 7~30 days, filtering
The dregs of a decoction, obtain black hair Chinese medicine composition.
Preferably, extracted using solvent dissolution, after filtering obtains filtrate, also included：The filtrate is carried out with oxygenated water
Dilution, obtains black hair Chinese medicine composition.
The present invention also provides a kind of black hair Chinese medicine preparation, and it includes black hair Chinese medicine composition mentioned above and pharmaceutically may be used
The auxiliary material of receiving.
Preferably, the formulation of the black hair Chinese medicine preparation is liquid dosage form, paste, creme or granule.
Compared with prior art, the application provide black hair Chinese medicine composition by including RADIX POLYGONI MULTIFLORI PREPARATA, cacumen biotae, the seed of Oriental arborvitae,
The raw material of SEMEN PINI KORAIENSIS, walnut kernel, glutinous rehmannia, Radix Angelicae Sinensis and the Radix Astragali is obtained.The present invention innovate instruction of Chinese Medicine theory under, by each Chinese medicine
Between rational compatibility application and synergy so that the composition of extraction can nourish scalp and hair follicle, with good black hair effect
Really.Inventive formulation is unique, and medicinal material used is pure plant Chinese medicine, any chemical composition is not added with the product being made and is added
Plus agent, safe and nontoxic, effect is good.
Further, the present invention prepares product using oxygenated water first, can preferably play nourishing, black hair effect.
Specific embodiment
The technical scheme in the embodiment of the present invention is clearly and completely described below, it is clear that described embodiment
Only a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, the common skill in this area
The every other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model of present invention protection
Enclose.
The invention provides a kind of black hair Chinese medicine composition for nourishing scalp and hair follicle, by the raw material system including following components
：
The RADIX POLYGONI MULTIFLORI PREPARATA of 1-100 weight portions；
The cacumen biotae of 1-80 weight portions；
The seed of Oriental arborvitae of 1-60 weight portions；
The SEMEN PINI KORAIENSIS of 1-60 weight portions；
The walnut kernel of 1-80 weight portions；
The glutinous rehmannia of 1-70 weight portions；
The Radix Angelicae Sinensis of 1-70 weight portions；
The Radix Astragali of 1-100 weight portions.
The black hair Chinese medicine composition that the present invention is provided can nourish scalp and hair follicle, hair is bleached to have and controls curative effect well
Really, it is and safe and nontoxic.
In the present invention, the raw material includes RADIX POLYGONI MULTIFLORI PREPARATA.RADIX POLYGONI MULTIFLORI PREPARATA is the Preparation process product of the fleece-flower root；Radix Polygoni Multiflori is by normal
The deep processing of rule, can obtain RADIX POLYGONI MULTIFLORI PREPARATA.The primary efficacy of RADIX POLYGONI MULTIFLORI PREPARATA is：Filling liver kidney, benefiting essence-blood, black beard and hair, strengthen the bone, wind-dispelling, solution
Poison.RADIX POLYGONI MULTIFLORI PREPARATA is for liver kidney deficiency of YIN-blood, it is impossible to which nourishing the deficiency of blood white hair caused by hair follicle hair has good therapeutic effect.
RADIX POLYGONI MULTIFLORI PREPARATA of the raw material of the present invention including 1~100 weight portion, preferably 2~50 weight portions, more preferably 3~
25 weight portions.In some specific embodiments of the invention, it is 5 weight portions, 15 weight portions or 20 weight portions.
In the present invention, the raw material includes cacumen biotae.Cacumen biotae is cupressaceae plant arbor-vitae PLatycladus
Orientalis (L.) Franco's dries branch and leaf；It is many to be harvested in summer, season in autumn two, dry in the shade and obtain final product.The main work(of cacumen biotae
Imitate and be：Cooling blood and hemostasis, growing and blacking hair.The alopecia and white hair that cacumen biotae causes for blood-head have good therapeutic effect, for
Deficiency of YIN-blood, the poliosis that blood-head is caused also has good effect.
Raw material of the present invention includes the cacumen biotae of 1~80 weight portion, preferably 2~40 weight portions, more preferably 3~20
Weight portion.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 15 weight portions.
In the present invention, the raw material includes the seed of Oriental arborvitae.The seed of Oriental arborvitae is cupressaceae plant arbor-vitae Platycladus
The dry mature kernal of orientalis (L.) Franco；Autumn, season in winter two harvesting mature seed, dry, and remove kind of a skin, collect and plant
Benevolence.The seed of Oriental arborvitae has functions that nourishing heart gas, kidney is dry for profit, intelligence development is allayed excitement；Its for deficiency of heart-blood, the main blood of the heart for causing of having no peace of mind
The main house mind's function of arteries and veins is damaged, and influence sleep and the state of mind cause to have grizzled hair with good efficacy.
Raw material of the present invention includes the seed of Oriental arborvitae of 1~60 weight portion, preferably 2~30 weight portions, more preferably 3~15
Weight portion.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 12 weight portions.
In the present invention, the raw material includes SEMEN PINI KORAIENSIS.SEMEN PINI KORAIENSIS for pinaceae plant Korean pine seed benevolence, also known as pine nut,
Korean pine seed etc..SEMEN PINI KORAIENSIS have tonify Qi of the kidney, enriching the blood and moisturizing the intestine, the function such as healthcare；Its hair for deficiency of the kidney the moon anemia damage
It is grizzled with very good effect.
Raw material of the present invention includes the SEMEN PINI KORAIENSIS of 1~60 weight portion, preferably 2~30 weight portions, more preferably 3~15
Weight portion.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 12 weight portions.
In the present invention, the raw material includes walnut kernel.Walnut kernel also known as juglandis,semen, Semen Juglandis, walnut this product are English walnut
The dry mature seed of section plant English walnut Juglans regia L.；Harvested during autumn fruit maturation, remove meat pericarp, shone
It is dry, then nucleocapsid and wooden barrier film are removed, obtain final product.Walnut kernel can be used for the strong waist of controlling nocturnal emission with astringent drugs, and warm lung Dingchuan relaxes bowel.For lung kidney
Virtual loss, fur loses hair that is foster and causing and bleaches, and walnut kernel has therapeutic effect well.
Raw material of the present invention includes the walnut kernel of 1~80 weight portion, preferably 2~40 weight portions, more preferably 3~20
Weight portion.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 15 weight portions.
In the present invention, the raw material includes glutinous rehmannia.The Classification system of glutinous rehmannia is：Rehmannia glutinosa
(Gaetn.) Libosch.ex Fisch.et Mey., Scrophulariaceae glutinous rehmannia belongs to herbaceos perennial.Because its underground root tuber is Huang
White and glutinous rehmannia of gaining the name, its root is one of traditional Chinese medicine, the earliest source of an allusion in《Sheng Nong's herbal classic》.According to concocting method in medicinal material
On be divided into：Fresh rehmannia root, dried rehamnnia root and prepared rhizome of rehmannia, the present invention use fresh rehmannia root.The primary efficacy of glutinous rehmannia is：Filling liver kidney, enriching yin are cool
Blood；It is then sent out for kidney deficiency and becomes homeless foster, it is impossible to which nourishing the white hair caused by hair has very good effect.
Raw material of the present invention includes the glutinous rehmannia of 1~70 weight portion, more preferably preferably 2~35 weight portions, 3~15 weights
Amount part.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 12 weight portions.
In the present invention, the raw material includes Radix Angelicae Sinensis.The scientific name of Radix Angelicae Sinensis is：Angelica sinensis, alias is dry to return,
The Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, culvert return that tail, Radix Angelicae Sinensis be bent, araliae cordatae, are perennial herb, and its root can enter
Medicine, is one of the most frequently used Chinese medicine.The primary efficacy of Radix Angelicae Sinensis is：Blood-supplementing blood-nourishing, menstruction regulating and pain relieving, moisturize laxation；Its for the deficiency of blood,
Blood can not support caused alopecia etc. has preferable curative effect.
Raw material of the present invention includes the Radix Angelicae Sinensis of 1~70 weight portion, more preferably preferably 2~35 weight portions, 3~15 weights
Amount part.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 12 weight portions.
In the present invention, the raw material includes the Radix Astragali.The Radix Astragali, also known as astragali or northern alpine yarrow, also makees astragalus or yellow alpine yarrow, is conventional
One of Chinese medicine, is the root of legume astragalus mongolicus or Astragalus membranacus.The Radix Astragali：Benefiting qi and nourishing blood, strengthening the spleen and replenishing qi.The present invention is by the Radix Astragali
Shared with Radix Angelicae Sinensis, the effect with qi-supplementing, blood-engendering, deficiency of qi and blood can be treated, the hair that scalp hair follicle loses caused by nutrition becomes
In vain, effect is fine.
Raw material of the present invention includes the Radix Astragali of 1~100 weight portion, preferably 2~50 weight portions, more preferably 3~25
Weight portion.In some specific embodiments of the invention, it is 5 weight portions, 10 weight portions or 15 weight portions.
In some embodiments of the invention, the black hair Chinese medicine composition is obtained by the raw material including following components：
The RADIX POLYGONI MULTIFLORI PREPARATA of 2-50 weight portions；
The cacumen biotae of 2-40 weight portions；
The seed of Oriental arborvitae of 2-30 weight portions；
The SEMEN PINI KORAIENSIS of 2-30 weight portions；
The walnut kernel of 2-40 weight portions；
The glutinous rehmannia of 2-35 weight portions；
The Radix Angelicae Sinensis of 2-35 weight portions；
The Radix Astragali of 2-50 weight portions.
In some embodiments of the invention, the black hair Chinese medicine composition is obtained by the raw material including following components：
The RADIX POLYGONI MULTIFLORI PREPARATA of 3-25 weight portions；
The cacumen biotae of 3-20 weight portions；
The seed of Oriental arborvitae of 3-15 weight portions；
The SEMEN PINI KORAIENSIS of 3-15 weight portions；
The walnut kernel of 3-20 weight portions；
The glutinous rehmannia of 3-15 weight portions；
The Radix Angelicae Sinensis of 3-15 weight portions；
The Radix Astragali of 3-25 weight portions.
Specifically, the black hair Chinese medicine composition is preferably obtained by the raw material including following components：The system of 20 weight portions is first
Crow；The cacumen biotae of 15 weight portions；The seed of Oriental arborvitae of 10 weight portions；The SEMEN PINI KORAIENSIS of 10 weight portions；The walnut kernel of 15 weight portions；12 weight
The glutinous rehmannia of part；The Radix Angelicae Sinensis of 15 weight portions；The Radix Astragali of 15 weight portions.
In a preferred embodiment of the invention, the raw material also includes appropriate oxygenated water, and this is important wound of the invention
Newly.Oxygenated water is the oxygen rich in micro-nano bubble in water, and the oxygen of micro-nano bubble has fine stability is kept in water
Aqueous vapor blending state.They can not only be used as solvent, and can play the oxygenating effect of oxygenated water, improve product
Overall drug effect, the absorption stimulated circulation with effective substance.Blood oxygen is dense during oxygenated water of the present invention has increase scalp
Degree, improves scalp hair follicle Hypoxia and ischemia state, increases the effect such as blood circulation of scalp sites, thus preferably play nourish,
The effect of black hair.
The traditional Chinese medical science thinks, is attributed to blood-head more white hair and contains partially：Young man's ferritic yang-energy wins partially, the burning hot heresy cloudy blood of easily consumption, causes
The scorching hair of the deficiency of blood loses supports and causes graying of hair；Or because of the deficiency of liver-yin and kidney-yin, asthenia of essence and blood, or deficiency of qi and blood, hair lose its support and
Bleach；Or because feelings will is bothered：The sad spleen of nervous, worried hypercedemonia, or depressed emotion, liver-qi depression, wood is strongly fragrant to multiply spleen, causes
The dysfunction of the spleen in transport, qi and blood transporting is passive, or qi depression to blood stasis, sends out Rong Erling hairs of becoming homeless early white.The composition bag of present invention treatment white hair
Include tool help the moon blood, clearing heat and cooling blood, it is promoting blood circulation and removing blood stasis the effects such as medicine, various ingredients Chinese medicine synergy, bleach tool to hair
There is good therapeutic effect.
According to the Meridian entry theory of herbal nature, medicine is for human body some internal organs, that channels and collaterals play the role of is special.White hair master
It is related to liver,kidney,spleen three dirty, from the medicine for entering the warps such as liver,kidney,spleen, combine the present invention treatment white hair, works well.
Inventive formulation is unique, and medicinal material used is pure plant Chinese medicine, any chemistry is not added with the product being made
Component additive agent, it is safe and nontoxic, effective.Composition product of the present invention is various informative, can be made easy to carry and use
Various dosage forms.
Present invention also offers the preparation method of black hair Chinese medicine composition mentioned above, comprise the following steps：By each group
After the prepared slices of Chinese crude drugs mixing for dividing, extracted as solvent using alcohol and/or water, obtained black hair Chinese medicine composition.
The embodiment of the present invention is constituted according to above-mentioned formula, weighs the prepared slices of Chinese crude drugs of respective amount, mixing.The present invention drinks to Chinese medicine
Piece, hybrid mode etc. are not particularly limited, using commonly used in the art.
Solvent, soak medicine are added in embodiment of the present invention medicinal material upon mixing obtains active ingredient dissolution, extraction
Black hair Chinese medicine composition.
The present invention carries out alcohol extracting or water extraction using alcohol and/or water as solvent.Present invention preferably employs alcoholic strength be 60~
65% liquor made from sorghum is extracted for solvent, from the pure plant-fermented high concentration liquor made from sorghum brewageed as Extraction solvent, both without
It is malicious effective, and orally available, safety and environmental protection.The embodiment of the present invention uses high concentration liquor made from sorghum (alcoholic strength 60-65%) for solvent enters
Row is extracted, and can extract alcohol-soluble active ingredient, and water-soluble active ingredient can be extracted again, so as to ensure that active ingredient in prescription
Maximum acquisition, can effectively reduce traditional Chinese medicine extyaction and not enough improve caused effective component loss.
In an embodiment of the present invention, after the prepared slices of Chinese crude drugs of each component are mixed, plus 6~10 times of volumes containing 60-65%
The liquor made from sorghum of ethanol soaks 7~30 days, fully makes effective ingredient dissolution, filters the dregs of a decoction, obtains black hair Chinese medicine composition.
The present invention is extracted using solvent dissolution, after filtering obtains filtrate, preferably also includes entering the filtrate with oxygenated water
Row dilution, obtains black hair Chinese medicine composition.The present invention prepares product using oxygenated water first, can preferably play nourishing, black hair
Effect.
Wherein, the present invention can add the aseptic oxygenated water isometric with it to be diluted in the filtered fluid of said extracted.
The embodiment of the present invention by said extracted thing be sufficiently mixed it is uniform after, it is filling and sterilize, can obtain black hair Chinese medicine composition, as crow
Hair plant essence stoste.
Aforesaid liquid concentration can be made concentrate, spray or lotion by the present invention；Wherein, the concentrate can also add
Plus appropriate auxiliary material is made semisolid paste, creme, it is also possible to coordinate with auxiliary material, by wet granulation or dry granulation, one
Step granulation is prepared into granule and uses.
Present invention also offers a kind of black hair Chinese medicine preparation, it includes black hair Chinese medicine composition mentioned above and pharmaceutically
Acceptable auxiliary material.
In the present invention, the black hair Chinese medicine preparation can be solid, semi-solid and liquid form.Described in the embodiment of the present invention
The formulation of black hair Chinese medicine preparation is liquid dosage form, is such as made concentrate, spray (painting) agent or lotion；Appropriate auxiliary material system can be added
Into semisolid paste, creme；Can also coordinate with auxiliary material, be prepared into by wet granulation or dry granulation, one-step palletizing
Granula is used.The present invention is not particularly limited to the auxiliary material, using pharmaceutically acceptable material commonly used in the art.
The formulation of preparation of the present invention such as spray, lotion, paste, creme or granule etc., type is various, beneficial to application.
In an embodiment of the present invention, the black hair Chinese medicine composition of liquid dosage form can be described as plant essence liquid；Its user
Method includes：Based on embrocating through scalp, once a day, each 15-20 minutes, scalp has cooling sensation when embrocating, it is also possible to applying
Before wiping, massage head or be close to head's skin combing hair with horn comb, make scalp telangiectasis, stimulate circulation, with
Beneficial to the osmotic absorption of nutrient solution.
Black hair traditional Chinese medicine preparation product safety non-toxic of the present invention, dual-use material can both take orally, it is also possible to external application, interior
Outer dual-purpose curative effect is more preferably.
For a further understanding of the application, the black hair Chinese medicine composition provided the application with reference to embodiment, its system
Preparation Method and its preparation are specifically described.
Embodiment 1
Weigh each prepared slices of Chinese crude drugs：RADIX POLYGONI MULTIFLORI PREPARATA 20g, cacumen biotae 15g, seed of Oriental arborvitae 10g, SEMEN PINI KORAIENSIS 10g, walnut kernel 15g, glutinous rehmannia
12g, Radix Angelicae Sinensis 12g, Radix Astragali 15g.
The prepared slices of Chinese crude drugs mixing of the respective amount that will be weighed, adds liquor made from sorghum of 8 times of volumes containing 65% ethanol, is stored in container
In, it is sealed in shady place and soaks 10 days, fully make effective ingredient dissolution, the dregs of a decoction are filtered, obtain filtered fluid.
The aseptic oxygenated water isometric with it is added in the filtered fluid of said extracted (to be had by this continent (Beijing) nanosecond science and technology
Limit company produces, and oxygen concentration is 32mg/L), it is diluted.
By said extracted thing be sufficiently mixed it is uniform after, it is filling and sterilize, obtain black hair plant essence stoste.
Embodiment 2
According to the method in embodiment 1, filtered fluid is obtained.
The light water isometric with it is added in the filtered fluid of said extracted, is diluted.
By said extracted thing be sufficiently mixed it is uniform after, it is filling and sterilize, obtain black hair plant essence stoste.
Embodiment 3
According to the formula in embodiment 1, each prepared slices of Chinese crude drugs are weighed.
The prepared slices of Chinese crude drugs mixing of the respective amount that will be weighed, adds 8 times of water of volume to be decocted 1 hour in 100 DEG C, filters medicine
Slag, obtains filtered fluid, as black hair plant essence stoste.
Embodiment 4
Weigh each prepared slices of Chinese crude drugs：RADIX POLYGONI MULTIFLORI PREPARATA 50g, cacumen biotae 40g, seed of Oriental arborvitae 30g, SEMEN PINI KORAIENSIS 30g, walnut kernel 40g, glutinous rehmannia
35g, Radix Angelicae Sinensis 35g, Radix Astragali 50g.
The prepared slices of Chinese crude drugs mixing of the respective amount that will be weighed, adds liquor made from sorghum of 8 times of volumes containing 65% ethanol, is stored in container
In, it is sealed in shady place and soaks 15 days, fully make effective ingredient dissolution, the dregs of a decoction are filtered, obtain filtered fluid.
The aseptic oxygenated water isometric with it is added in the filtered fluid of said extracted, is diluted.
By said extracted thing be sufficiently mixed it is uniform after, it is filling and sterilize, obtain black hair plant essence stoste.
Embodiment 5
Weigh each prepared slices of Chinese crude drugs：RADIX POLYGONI MULTIFLORI PREPARATA 10g, cacumen biotae 8g, seed of Oriental arborvitae 5g, SEMEN PINI KORAIENSIS 5g, walnut kernel 8g, glutinous rehmannia 6g,
Radix Angelicae Sinensis 6g, Radix Astragali 8g.
The prepared slices of Chinese crude drugs mixing of the respective amount that will be weighed, adds liquor made from sorghum of 8 times of volumes containing 65% ethanol, is stored in container
In, it is sealed in shady place and soaks 20 days, fully make effective ingredient dissolution, the dregs of a decoction are filtered, obtain filtered fluid.
The aseptic oxygenated water isometric with it is added in the filtered fluid of said extracted, is diluted.
By said extracted thing be sufficiently mixed it is uniform after, it is filling and sterilize, obtain black hair plant essence stoste.
Embodiment 6
Observe black hair effect of each hair blackening product to white hair patient：
1st, test specimen
The test specimen that this experiment is used：The products obtained therefrom of embodiment 1 (alcohol extracting+oxygenated water Essence 1), the gained of embodiment 2
Product (alcohol extracting+light water Essence), the products obtained therefrom of embodiment 3 (water extraction Essence), being the hair biotechnology of Beijing heart hundred million has
Limit company provides, using same formula by Different Preparation embodiment 4 (alcohol extracting+hydrogeneous water Essence 2), embodiment 5
(alcohol extracting+hydrogeneous water Essence 3) is made, and wherein embodiment 1,2,4,5 is alcohol extract, and its difference is follow-up alcohol extract point
Oxygenated water is not employed and light water is diluted and forms, and water extraction Essence is formed using water decoction filtering.
Comparative sample is：Blackening hair hair follicle Essence (auspiciousness trump blackening hair hair follicle Essence is bought by Taobao).
2nd, clinical data
180 white hair patients of this group, man 120, female 60, age reckling 18 years old, the maximum 56 years old, 24-50 year persons
Account for 90%.120 males and 60 female patients are equally divided into 6 groups, every group of male 20, women 10.Respectively alcohol extracting+
1 group of oxygenated water Essence, alcohol extracting+2 groups of oxygenated water Essence, alcohol extracting+3 groups of oxygenated water Essence, alcohol extracting+light water Essence
Group, water extraction Essence group and blackening hair hair follicle Essence group.
3rd, test method
Above-mentioned alcohol extracting+1 group of oxygenated water Essence, alcohol extracting+2 groups of oxygenated water Essence, alcohol extracting+3 groups of oxygenated water Essence, alcohol
+ light water Essence group, water extraction Essence group and blackening hair hair follicle Essence group are put forward, is embrocated through scalp, once a day, often
Secondary 15-20 minutes, each consumption is 4mL.
4th, curative effect and result
(1), efficacy assessment standard
It is using the efficacy assessment standard of hair blackening product to white hair patient：It is effective：White hair area 50%-80% grows new hair
Dark hair, newly sends out without exception；Take a turn for the better or effective：It is dark hair that white hair area 10%-50% grows new hair, but slow-growing；It is invalid：Without bright
Aobvious dark hair grows or white hair continued growth.
(2), result of the test
In alcohol extracting+patient of oxygenated water Essence 1 group 30, effective 23 account for 76.7%, and effective 6 account for 20%, invalid 1
3.3% is accounted for, total effective rate is 96.7%.In alcohol extracting+patient of oxygenated water Essence 2 group 30, effective 21 account for 70%, effective 8
Example accounts for 26.7%, and invalid 1 accounts for 3.3%, and total effective rate is 96.7%.In alcohol extracting+patient of oxygenated water Essence 3 group 30, show
Effect 16 accounts for 53.3%, and effective 8 account for 26.7%, and invalid 6 account for 20%, and total effective rate is 80%.
In alcohol extracting+30 patients of light water Essence group, effective 17 account for 56.7%, and effective 9 account for 30%, invalid 4
13.3% is accounted for, total effective rate is 86.7%.
In 30 patients of water extraction Essence group, effective 15 account for 50%, and effective 8 account for 26.7%, and invalid 7 account for
23.3%, total effective rate is 76.7%.
In blackening hair hair follicle Essence 30 patients of group, effective 12 account for 40%, and effective 6 account for 20%, invalid 12
40% is accounted for, total effective rate is 60%.
Specific test result is present invention difference black hair test specimen to the action effect of white hair patient referring to table 1, table 1.
Action effect of the present invention of the table 1 difference black hair test specimen to white hair patient
| Group | Number of cases | It is effective | Effectively | It is invalid |
| Alcohol extracting+oxygenated water Essence 1 | 30 | 23 (76.7%) | 6 (20%) | 1 (3.3%) |
| Alcohol extracting+oxygenated water Essence 2 | 30 | 21 (70%) | 8 (26.7%) | 1 (3.3%) |
| Alcohol extracting+oxygenated water Essence 3 | 30 | 16 (53.3%) | 8 (26.7%) | 6 (20%) |
| Alcohol extracting+light water Essence | 30 | 17 (56.7%) | 9 (30%) | 4 (13.3%) |
| Water extraction Essence | 30 | 15 (50%) | 8 (26.7%) | 7 (23.3%) |
| Blackening hair hair follicle Essence | 30 | 12 (40%) | 6 (20%) | 12 (40%) |
It can be seen that, 6 groups of test specimens can change patient's white hair situation, but alcohol extracting+1 group of oxygenated water Essence is substantially better than
Other each groups outside alcohol extracting+2 groups of oxygenated water Essence, its total effective rate is up to 96.7%.The effect may can with oxygenated water
Improve scalp and the local oxygen-supplying amount of hair follicle, promote blood supply, the nutrition for increasing hair is relevant.Alcohol extracting+oxygenated water Essence 2
It is suitable with its effect, but, manufacturing cost is higher than alcohol extracting+oxygenated water Essence 1.
As seen from the above embodiment, the product of the invention can be played not to different crowd, different white hair producing causes
With the recovery of degree, improvement result.
The above is only the preferred embodiment of the present invention, it is noted that for making the professional technique of the art
Personnel, on the premise of the technology of the present invention principle is not departed from, are that by various modifications of these embodiments, and these
Modification also should be regarded as the scope that the present invention should be protected.
Claims (10)
1. a kind of black hair Chinese medicine composition for nourishing scalp and hair follicle, is obtained by the raw material including following components：
The RADIX POLYGONI MULTIFLORI PREPARATA of 1-100 weight portions；
The cacumen biotae of 1-80 weight portions；
The seed of Oriental arborvitae of 1-60 weight portions；
The SEMEN PINI KORAIENSIS of 1-60 weight portions；
The walnut kernel of 1-80 weight portions；
The glutinous rehmannia of 1-70 weight portions；
The Radix Angelicae Sinensis of 1-70 weight portions；
The Radix Astragali of 1-100 weight portions.
2. black hair Chinese medicine composition according to claim 1, it is characterised in that be obtained by the raw material including following components：
The RADIX POLYGONI MULTIFLORI PREPARATA of 2-50 weight portions；
The cacumen biotae of 2-40 weight portions；
The seed of Oriental arborvitae of 2-30 weight portions；
The SEMEN PINI KORAIENSIS of 2-30 weight portions；
The walnut kernel of 2-40 weight portions；
The glutinous rehmannia of 2-35 weight portions；
The Radix Angelicae Sinensis of 2-35 weight portions；
The Radix Astragali of 2-50 weight portions.
3. black hair Chinese medicine composition according to claim 2, it is characterised in that be obtained by the raw material including following components：
The RADIX POLYGONI MULTIFLORI PREPARATA of 3-25 weight portions；
The cacumen biotae of 3-20 weight portions；
The seed of Oriental arborvitae of 3-15 weight portions；
The SEMEN PINI KORAIENSIS of 3-15 weight portions；
The walnut kernel of 3-20 weight portions；
The glutinous rehmannia of 3-15 weight portions；
The Radix Angelicae Sinensis of 3-15 weight portions；
The Radix Astragali of 3-25 weight portions.
4. the black hair Chinese medicine composition according to any one of claims 1 to 3, it is characterised in that the raw material also includes
Oxygenated water.
5. the preparation method of the black hair Chinese medicine composition any one of claims 1 to 3, comprises the following steps：
After the prepared slices of Chinese crude drugs of each component are mixed, extracted as solvent using alcohol and/or water, obtained black hair Chinese traditional medicine composition
Thing.
6. preparation method according to claim 5, it is characterised in that the solvent is sorghum that alcoholic strength is 60~65%
Wine.
7. preparation method according to claim 6, it is characterised in that after the prepared slices of Chinese crude drugs of each component are mixed, plus 6~10
The liquor made from sorghum of times volume soaks 7~30 days, filters the dregs of a decoction, obtains black hair Chinese medicine composition.
8. the preparation method according to claim 5 or 6, it is characterised in that extracted using solvent dissolution, filtering obtains filtrate
Afterwards, also include：The filtrate is diluted with oxygenated water, black hair Chinese medicine composition is obtained.
9. a kind of black hair Chinese medicine preparation, it is characterised in that including the black hair Chinese traditional medicine composition any one of Claims 1 to 4
Thing and pharmaceutically acceptable auxiliary material.
10. black hair Chinese medicine preparation according to claim 9, it is characterised in that the formulation of the black hair Chinese medicine preparation is liquid
Body formulation, paste, creme or granule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113142554A (en) * | 2020-06-09 | 2021-07-23 | 江苏佰澳达生物科技有限公司 | Probiotic fermentation liquor for improving dandruff production and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804117A (en) * | 2010-04-16 | 2010-08-18 | 袁仲元 | Hair growing and blacking liquid and preparation process thereof |
| CN101972221A (en) * | 2010-11-03 | 2011-02-16 | 宁夏欣发宝养发有限公司 | Hair blacking liquid and preparation method thereof |
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2017
- 2017-03-08 CN CN201710133778.3A patent/CN106728338A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804117A (en) * | 2010-04-16 | 2010-08-18 | 袁仲元 | Hair growing and blacking liquid and preparation process thereof |
| CN101972221A (en) * | 2010-11-03 | 2011-02-16 | 宁夏欣发宝养发有限公司 | Hair blacking liquid and preparation method thereof |
| CN102319286A (en) * | 2010-11-03 | 2012-01-18 | 宁夏欣发宝养发有限公司 | Hair blackening liquid and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113142554A (en) * | 2020-06-09 | 2021-07-23 | 江苏佰澳达生物科技有限公司 | Probiotic fermentation liquor for improving dandruff production and application thereof |
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Application publication date: 20170531 |