CN106727710A - A kind of preparation method of placenta nutrient powder - Google Patents
A kind of preparation method of placenta nutrient powder Download PDFInfo
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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Abstract
The invention discloses a kind of preparation method by placenta nutrient powder, comprise the following steps：Learnt from else's experience the placenta of inspection and quarantine, removed manadesma and blood vessel, cleaned up with aseptic deionized water, be placed in 20 30min in infrared sterilization equipment, took out standby；After the placenta powder after sterilizing aseptically is mixed into 2~3min with starch, syrup is slowly added in mixing, thing to be mixed adds 50% ginseng pulverate to continue to stir when stirring to loose condition (of surface), until stirring；21 25 parts of placenta powder, 35 parts of starch, 10 12 parts of syrup, 5 10 parts of ginseng pulverate；The beneficial effects of the invention are as follows：Such as protein, microbiology class can be kept will not be denatured and lose its bioactivity；The physicochemical property and bioactivity of original aqueous solution can be quickly dissolved and recovered after adding water, and because drying is carried out under vacuum, there is good protective effect for some oxidizable materials.Placenta water content after lyophilized is extremely low, improves the stability of product, extends the product pot-life.
Description
Technical field
The invention belongs to the manufacture field of nutriment, and in particular to be a kind of preparation method of placenta nutrient powder.
Background technology
The nutrition organs that placenta starts for life, its is nutritious, with righting qi-restoratives, replenish qi to invigorate the spleen, nourishing blood and replenishing essence, benefit
The vital organs of the human body are had the function of repairing anti-disease by effect of kidney and enhancing body.Experts and scholars study ratio to the placenta of people and sheep in recent years
It is more deep, and product is more, but the research to pig or Cow placeta is little.In traditional concept, placenta is taken by fetus
Business, be that fetus transmits various accurate nutrition after conversion, therefore its very suitable human body, real to belong to non-defective unit of being bestowed by heaven, inside it
Possess the gold elements such as the amino acid and panimmunity globulin of 8 types, human body is not only craved for and easily absorbed, but also
The symptom reparation that human body can have been occurred to the connatae initial most original of neonate disease-free state, to occur disease enter
Row is repaired and built up health, from the puzzlement of intractable diseases.
And study and find, containing very abundant candidate stem cell (HSC) in Cord blood, human body hematopoiesis can be rebuild and exempted from
Epidemic disease system, can be used for HSCT, treatment hematological system, immune system, and hereditary metabolic disorders and congenital disorders.
Therefore, Cord blood has turned into the important sources of candidate stem cell, has been widely used in clinic, is valuable human biological
Resource；The discriminating of Goat Placenta " dried human placenta with " and " true and false discriminating of dried human placenta and its difference with pig placenta " two articles simultaneously
In point out, dried human placenta (Human plactnta) and Goat Placenta differentiate that collection of illustrative plates differs larger, similar to pig placenta, micro- to have difference；Dried human placenta with
The hard crisp frangibility of pig placenta, body are light, and Goat Placenta matter is hard, be not easily broken." Chinese medicine dried human placenta and pig, ox, Goat Placenta are enriched blood work
The placenta and dried human placenta of pig, ox or sheep are pointed out in pharmacological experiment study " article to be had and its close work(at aspect of enriching blood
Effect, but not have dried human placenta good for nutritive value and immunology.
Placenta class product is although nutritious, and health care and medical value are higher, but is easily carried pathogenic microorganisms and compares
It is many.Therefore, preparing placenta class medicine needs strictly to process placenta.However, traditional placenta processing and treating method is not only
Time-consuming, condition harsh, and active principle and nutritional ingredient destruction are serious.
The content of the invention
In order to solve the above technical problems, can keep nutritional activities the invention provides one kind, contaminated chance reduces,
The preparation method of the placenta nutrient powder of storage life limit for length.
To achieve the above object, the technical solution adopted by the present invention is a kind of preparation method by placenta nutrient powder, including
Following steps：
S1. learnt from else's experience the placenta of inspection and quarantine, removed manadesma and blood vessel, cleaned up with aseptic deionized water, be placed in red
20-30min in outside line disinfection equipment, takes out standby；
S2. gained placenta in step S1 is placed in dicer, is cut into filament shape, be subsequently placed in throughcirculation dryer, led to
Enter low-temperature cold wind to be dried；
S3. gained in step S2 is dried placenta and is placed in and 5-10min is soaked in Bitter Melon Juice, then taking out carries out cryogenic vacuum
Dry, temperature is less than 10 DEG C；
S4. gained dried object in step S3 is carried out into ultramicro grinding, obtains placenta powder of the particle diameter in 3~5um；
S5. the placenta powder of gained in step S4 is screened by 600 eye mesh screens, is removed bulk impurity；
S6. by ultraviolet sterilization while gained placenta powder carries out air blast in step S5；
S7. after the placenta powder after sterilizing aseptically being mixed into 2~3min with starch, sugar is slowly added in mixing
Slurry, thing to be mixed adds 50% ginseng pulverate to continue to stir when stirring to loose condition (of surface), until stirring；
S8. by step S7 gained the mixture for stirring by sterilizing, sterilization after low temperature conversion be freeze-dried powder；
S9. the freeze-dried powder of gained in step S8 being added with can reduce hydrochloric acid in gastric juice and the plant drymeal mixing containing vitamin
After put into capsule.
As the placenta that preferred scheme of the invention, the placenta in step S1 are behaved.
Used as preferred scheme of the invention, the Bitter Melon Juice preparation method in step S3 is to select fresh bitter, by fresh hardship
After melon is cleaned up, blended after adding 10g ginger slices, block is leached after blending, only left juice.
As preferred scheme of the invention, in step S6 can air blast and ultraviolet sterilization carry out simultaneously, it is also possible to separately enter
OK, sequencing and is not limited.
Used as preferred scheme of the invention, each material is respectively by weight in step S7, placenta powder 21-25 parts, starch
3-5 parts, syrup 10-12 parts, ginseng pulverate 5-10 parts.
As preferred scheme of the invention, in step S9 can reduce hydrochloric acid in gastric juice and the plant drymeal containing vitamin is made a living
Ginger powder.
The beneficial effects of the invention are as follows：Such as protein, microbiology class can be kept will not be denatured and lose its biology
Activity；The physicochemical property and bioactivity of original aqueous solution can be quickly dissolved and recovered after adding water.Due to drying in vacuum bar
Carried out under part, there is good protective effect for some oxidizable materials.Placenta water content after lyophilized is extremely low, makes
The stability of product is improved, and contaminated chance reduces, and extends the product pot-life, and ensure that active material is not corroded
And effectively absorb, candidate stem cell and immunoglobulin etc. can be pinned in vivo, it is ensured that constant absorption.
Specific embodiment
With reference to specific embodiment the present invention will be further explained explanation, but protection model of the invention is not limited
Enclose.
Embodiment one
A kind of preparation method by placenta nutrient powder of the invention, comprises the following steps：
S1. learnt from else's experience the placenta of inspection and quarantine, removed manadesma and blood vessel, cleaned up with aseptic deionized water, be placed in red
20-30min in outside line disinfection equipment, takes out standby；
S2. gained placenta in step S1 is placed in dicer, is cut into filament shape, be subsequently placed in throughcirculation dryer, led to
Enter low-temperature cold wind to be dried；
S3. gained in step S2 is dried placenta and is placed in and 5-10min is soaked in Bitter Melon Juice, then taking out carries out cryogenic vacuum
Dry, temperature is less than 10 DEG C；
S4. gained dried object in step S3 is carried out into ultramicro grinding, obtains placenta powder of the particle diameter in 3~5um；
S5. the placenta powder of gained in step S4 is screened by 600 eye mesh screens, is removed bulk impurity；
S6. by ultraviolet sterilization while gained placenta powder carries out air blast in step S5；
S7. after the placenta powder after sterilizing aseptically being mixed into 2~3min with starch, sugar is slowly added in mixing
Slurry, thing to be mixed adds 50% ginseng pulverate to continue to stir when stirring to loose condition (of surface), until stirring；
S8. by step S7 gained the mixture for stirring by sterilizing, sterilization after low temperature conversion be freeze-dried powder；
S9. the freeze-dried powder of gained in step S8 being added with can reduce hydrochloric acid in gastric juice and the plant drymeal mixing containing vitamin
After put into capsule.
Placenta in described step S1 is sheep or the placenta of horse or ox of health.
Bitter Melon Juice preparation method in described step S3 is to select fresh bitter, after fresh bitter is cleaned up, plus
Blended after entering 10g ginger slices, block is leached after blending, only left juice.
In described step S6 can air blast and ultraviolet sterilization carry out simultaneously, it is also possible to separately carry out, and do not limit elder generation
Afterwards sequentially.
Each material is respectively by weight in described step S7：21 parts of placenta powder, 3 parts of starch, 10 parts of syrup, ginseng pulverate
5 parts.
Can reduce hydrochloric acid in gastric juice and the plant drymeal containing vitamin in described step S9 are ginger powder.
Contain substantial amounts of immunoglobulin, high protein, immunocompetent cell in placenta, the placenta after physical squeezing is carried out
Substance decomposition, is decomposed and freeze-dried powder is converted into by way of vacuum dehydrating at lower temperature after extracting, for thermal sensitivity product in placenta and
The material of holding bioactivity is needed, it is a kind of effective method to freeze.This method is that dry intacellin matter will be needed to exist
Freeze the moisture contained by it under low temperature, be then placed on drying in the environment of vacuum, allow moisture directly to rise Huawei by solid state
Vapor is simultaneously excluded from placenta and dries placenta.The method effectively prevent the change of product physics and chemistry and biological nature,
Damage to biological tissue and eucaryotic cell structure and feature is smaller, it is rapidly entered resting state, effectively protects many temperature-sensitives
The stability of property placenta effective ingredient.As protein, microbiology class will not be denatured and lose its bioactivity；Energy after adding water
Enough physicochemical properties and bioactivity for quickly dissolving and recovering original aqueous solution.Because drying is carried out under vacuum, for
Some oxidizable materials have good protective effect.Placenta water content after lyophilized is extremely low, makes the stability of product
Improve, contaminated chance reduces, and extends the product pot-life；Can directly wash by water and take.
Embodiment two
A kind of preparation method by placenta nutrient powder of the invention, comprises the following steps：
S1. learnt from else's experience the placenta of inspection and quarantine, removed manadesma and blood vessel, cleaned up with aseptic deionized water, be placed in red
20-30min in outside line disinfection equipment, takes out standby；
S2. gained placenta in step S1 is placed in dicer, is cut into filament shape, be subsequently placed in throughcirculation dryer, led to
Enter low-temperature cold wind to be dried；
S3. gained in step S2 is dried placenta and is placed in and 5-10min is soaked in Bitter Melon Juice, then taking out carries out cryogenic vacuum
Dry, temperature is less than 10 DEG C；
S4. gained dried object in step S3 is carried out into ultramicro grinding, obtains placenta powder of the particle diameter in 3~5um；
S5. the placenta powder of gained in step S4 is screened by 600 eye mesh screens, is removed bulk impurity；
S6. by ultraviolet sterilization while gained placenta powder carries out air blast in step S5；
S7. after the placenta powder after sterilizing aseptically being mixed into 2~3min with starch, sugar is slowly added in mixing
Slurry, thing to be mixed adds 50% ginseng pulverate to continue to stir when stirring to loose condition (of surface), until stirring；
S8. by step S7 gained the mixture for stirring by sterilizing, sterilization after low temperature conversion be freeze-dried powder；
S9. the freeze-dried powder of gained in step S8 being added with can reduce hydrochloric acid in gastric juice and the plant drymeal mixing containing vitamin
After put into capsule.
Placenta in described step S1 is sheep or the placenta of horse or ox of health.
Bitter Melon Juice preparation method in described step S3 is to select fresh bitter, after fresh bitter is cleaned up, plus
Blended after entering 10g ginger slices, block is leached after blending, only left juice.
In described step S6 can air blast and ultraviolet sterilization carry out simultaneously, it is also possible to separately carry out, and do not limit elder generation
Afterwards sequentially.
Each material is respectively by weight in described step S7：25 parts of placenta powder, 5 parts of starch, 12 parts of syrup, ginseng pulverate
10 parts.
Can reduce hydrochloric acid in gastric juice and the plant drymeal containing vitamin in described step S9 are chamomile powder.
The placenta nutrient powder being made up of the present invention can also directly be taken or tabletted.
The traditional Chinese medical science thinks that placenta nature and flavor are sweet, salty, temperature, enter lung, liver and kidney channel, there is benefit essence, blood-nourishing, the work(of QI invigorating.For kidney qi
Deficiency, essence and blood decline less caused infertile or impotence, seminal emission, dizziness, tinnitus etc. card.Can be used for deficiency of qi and blood, weak, complexion of becoming thin
Sallow, postpartum is newborn few.Can be used for the asthma of deficiency of both the lung and kidney, this product is especially taken when not breaking out, can consolidate, reduce breaking-out.
In addition, it may also be used for treatment deficiency of qi and blood, hair is more than long for epilepsy.General consumption 1.5g-3g, grind it is encapsulated swallow, one day two,
Three times, consumption is demonstrate,proved again and is doubled.Also ball can be entered to dissipate.Note：Fire excess from yin deficiency person should not be used alone.
Modern medicine study thinks, placenta containing protein, sugar, calcium, vitamin, immune factor, female sex hormone, help progesterone,
Steroid hormone, promoting sexual gland hormone, corticotropin etc., can promote the development of mammary gland, uterus, vagina, testis, to first
Shape gland also has facilitation, also has good effect to pulmonary tuberculosis, bronchial astehma, anaemia etc., and grinding oral or bowel lavage can prevent measles
Or mitigate symptom.Also there is certain curative effect to portal cirrhotic ascites and blood fluke property end-age cirrhosis ascites.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be in other specific forms realized.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires to be limited rather than described above, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention, and any mark in claim should not be considered as the claim involved by limitation.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each implementation method is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should
Specification an as entirety, the technical scheme in each embodiment can also be formed into those skilled in the art through appropriately combined
May be appreciated other embodiment.
Claims (6)
1. a kind of preparation method by placenta nutrient powder, comprises the following steps：
S1. learnt from else's experience the placenta of inspection and quarantine, removed manadesma and blood vessel, cleaned up with aseptic deionized water, be placed in infrared ray
20-30min in disinfection equipment, takes out standby；
S2. gained placenta in step S1 is placed in dicer, is cut into filament shape, be subsequently placed in throughcirculation dryer, be passed through low
Warm cold wind is dried；
S3. gained in step S2 is dried placenta and is placed in 5-10min is soaked in Bitter Melon Juice, then taking out carries out cryogenic vacuum and do
Dry, temperature is less than 10 DEG C；
S4. gained dried object in step S3 is carried out into ultramicro grinding, obtains placenta powder of the particle diameter in 3~5um；
S5. the placenta powder of gained in step S4 is screened by 600 eye mesh screens, is removed bulk impurity；
S6. by ultraviolet sterilization while gained placenta powder carries out air blast in step S5；
S7. after the placenta powder after sterilizing aseptically being mixed into 2~3min with starch, syrup is slowly added in mixing,
Thing to be mixed adds 50% ginseng pulverate to continue to stir when stirring to loose condition (of surface), until stirring；
S8. by step S7 gained the mixture for stirring by sterilizing, sterilization after low temperature conversion be freeze-dried powder；
S9. the freeze-dried powder of gained in step S8 is added with after can reducing hydrochloric acid in gastric juice and the plant drymeal mixing containing vitamin and is filled
Enter capsule.
2. a kind of preparation method by placenta nutrient powder according to claim 1, it is characterised in that：In described step S1
Placenta behave placenta.
3. a kind of preparation method by placenta nutrient powder according to claim 1, it is characterised in that：In described step S3
Bitter Melon Juice preparation method be to select fresh bitter, after fresh bitter is cleaned up, add 10g ginger slices after blended,
Block is leached after blending, juice is only left.
4. a kind of preparation method by placenta nutrient powder according to claim 1, it is characterised in that：In described step S6
Can air blast and ultraviolet sterilization carry out simultaneously, it is also possible to separately carry out, and do not limit sequencing.
5. a kind of preparation method by placenta nutrient powder according to claim 1, it is characterised in that：In described step S7
Each material is respectively by weight, placenta powder 21-25 parts, starch 3-5 parts, syrup 10-12 parts, ginseng pulverate 5-10 parts.
6. the preparation method of a kind of placenta nutrient powder according to claim 1, it is characterised in that：In described step S9
It is ginger powder that hydrochloric acid in gastric juice and the plant drymeal containing vitamin can be reduced.
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| CN201710195176.0A CN106727710A (en) | 2017-03-29 | 2017-03-29 | A kind of preparation method of placenta nutrient powder |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352523A (en) * | 2014-10-14 | 2015-02-18 | 磐安县道地磐药中药研究所 | Human placenta pure powder superfine decoction pieces and preparation method thereof |
| CN105030831A (en) * | 2015-09-19 | 2015-11-11 | 山东中泰药业有限公司 | Placental drug and preparation method thereof |
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2017
- 2017-03-29 CN CN201710195176.0A patent/CN106727710A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352523A (en) * | 2014-10-14 | 2015-02-18 | 磐安县道地磐药中药研究所 | Human placenta pure powder superfine decoction pieces and preparation method thereof |
| CN105030831A (en) * | 2015-09-19 | 2015-11-11 | 山东中泰药业有限公司 | Placental drug and preparation method thereof |
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Application publication date: 20170531 |