CN106723075A - A kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations and preparation method thereof - Google Patents
A kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations and preparation method thereof Download PDFInfo
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- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to traditional Chinese medicine health care product technical field, specifically a kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations and preparation method thereof, it is characterized in that said preparation is made up of holothurian collagen Gly-His-Lys, ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal zinc sulfate, selenide of carragheen, the weight portion of above-mentioned each constituent is：10 30 parts of holothurian collagen Gly-His-Lys, 5 20 parts of ginseng powder, 20 40 parts of seabuckthorn fruit powder, 10 15 parts of G-protein, 20 45 parts of Herba Cistanches powder, 3 10 parts of medicinal zinc sulfate, 0.01-0.05 part of selenide of carragheen, with reinforcing vital energy, the advantages of strengthen immunity, discharging garbage from body, anti-aging, the effect is significant that sets up.
Description
Technical field
The present invention relates to traditional Chinese medicine health care product technical field, specifically one kind is reinforced vital energy, strengthen immunity, exclusion body
Interior rubbish, anti-aging, the double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations for the effect is significant that sets up and preparation method thereof.
Background technology
At present, with the development of social economy, the growth in the living standard of people, people are to the attention of own health and support
Raw requirement degree is more and more stronger, but, due to the quickening of work rhythm, the reduction of the increase of operating pressure, and motion, people
Immunity it is generally low, immunity is the defense mechanism of human body itself, is human bioequivalence and eliminates any of external intrusion
Material, treatment aging, damage, death, the own cells of denaturation and identification and treatment vivo mutations cell and virus infection are thin
The ability of born of the same parents, the body of hypoimmunity is easy to infected or cancer stricken, and immunity overlength also can produce infringement, such as mistake to body
Quick reaction, autoimmunity disease etc., a variety of causes prevent immune system from normally playing protective effect, in the case, easily recruit
Cause bacterium, virus, the infection such as fungi, therefore hypoimmunity most directly performance be exactly it is liable to illness, it is particularly easily tired
Labor, and the symptoms such as functions of expelling toxin weakens, aging is accelerated particularly are easily caused in the case of hypoimmunity.
The content of the invention
Present invention aim to address above-mentioned the deficiencies in the prior art, there is provided one kind is reinforced vital energy, strengthen immunity, exclusion
Internal rubbish, anti-aging, double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations of the effect is significant that sets up and preparation method thereof.
The technical solution adopted for the present invention to solve the technical problems is：
A kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations, it is characterised in that said preparation by holothurian collagen Gly-His-Lys, the West
Ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal zinc sulfate, selenide of carragheen composition, the weight portion of above-mentioned each constituent
For：10-30 parts of holothurian collagen Gly-His-Lys, ginseng powder 5-20 parts, seabuckthorn fruit powder 20-40 parts, G-protein 10-15 parts, Herba Cistanches powder
20-45 parts, medicinal zinc sulfate 3-10 parts, 0.01-0.05 part of selenide of carragheen.
The weight ratio optimized in each composition of the present invention is 25-30 parts of holothurian collagen Gly-His-Lys, ginseng powder
14-17 parts, seabuckthorn fruit powder 22-38 parts, G-protein 11-14 parts, 30-38 parts of Herba Cistanches powder, medicinal zinc sulfate 4-7 parts, selenide of carragheen
0.01-0.05 part.
A kind of preparation method of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations, it is characterised in that the technique step of preparation method
It is rapid as follows：
（1）：Holothurian collagen Gly-His-Lys：New fresh sea cucumber cleaned first, is cut off, removing internal organ, what reservation was flowed out contains sea
Join the liquid of the enzyme of self-dissolving, and the impurity in the sea cucumber intestine and sea cucumber in sea cucumber internal organ is cleared, sea cucumber intestine and sea cucumber one
And standby, ball milling mashing after then crushing sea cucumber, sea cucumber intestine and sea cucumber, add in enzymatic vessel, add the 5 of sea cucumber raw material
~ 10 times of water, adds the liquid and appropriate food flavor enzyme of the enzyme containing sea cucumber self-dissolving of reservation, is well mixed, and opens steam and opens
Close, 45 ~ 65 DEG C are warming up to gradually, under conditions of being stirred continuously, maintain constant temperature 3.5 ~ 4 hours, treat that whole liquid is clarified substantially
100 DEG C, after 5 ~ 10 minutes are warming up to, gained supernatant liquid adjustment concentration is 2% ~ 10%, then with clean spray by cooling filtering
Dry tower is spray-dried, and after the assay was approved, polybag vacuumizes packaging to the spray powder of gained, and Cord blood is standby；
(2) American Ginseng:Buy the American Ginseng of qualified qualification unit, together with the laboratory test report of the unit, send inspection center according to《China
Pharmacopeia》Version is tested within 2015.The qualified raw material of inspection is taken, is added water with JYL-5 broken wall cooking machines and carry out broken wall treatment in right amount,
With pressure 0.09MP temperature controls at 40 degree, after ORW105 microwave vacuum dryers are dried, with qualified stainless steel pulverizer powder
It is broken, reach 150 mesh.Moisture≤5%, saves backup.
（3）Sea-buckthorn：Inspection center is sent to check the sea-buckthorn fine powder bought in qualified unit, a test rating is closed
Lattice, are added water with JYL-5 broken wall cooking machines and carry out broken wall treatment in right amount, and with pressure 0.09MP temperature controls at 40 degree, ORW105 is micro-
After ripple vacuum drier is dried, then by seabuckthorn fruit powder dried process after, crushed with clean stainless steel pulverizer, then mistake
120 eye mesh screens, it is standby after gained powder-tight is packed；
（4）G-protein：Purchase has the angle swallow G-protein of qualification unit, together with unit laboratory test report of selling goods, send inspection center to check,
JYL-5 broken walls cooking machine adds water and carry out broken wall treatment in right amount again, and with pressure 0.09MP temperature controls at 40 degree, ORW105 is micro-
After ripple vacuum drier is dried, crushed with qualified stainless steel pulverizer, cross 120 mesh sieves, moisture≤5% packs standby
With.
（5）Saline cistanche：The saline cistanche that will be bought in qualified unit, send inspection center to check, and test rating is qualified,
Saline cistanche is added water with JYL-5 broken wall cooking machines again carry out broken wall treatment in right amount, with pressure 0.09MP temperature controls at 40 degree,
After ORW105 microwave vacuum dryers are dried, crushed with clean stainless steel pulverizer, 120 eye mesh screens are then crossed, by institute
Obtain standby after powder-tight is packed；
（6）：Take selenide of carragheen, medicinal zinc sulfate, to send inspection center to check qualified, then selenide of carragheen and zinc sulfate are distinguished
After drying, be put into cleaning stainless steel pulverizer in crushed, then cross 100 eye mesh screens, by gained powder-tight pack after
It is standby；
（7）According to recipe requirements, by holothurian collagen Gly-His-Lys, ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal sulphur
Sour zinc, selenide of carragheen, put three-dimensional mixer and fully mix,
（8）Granulation and arrangement grain：According to granulating process, 60-70% alcohol granulations are used, be dried at a temperature of 80-90 degree, so
Whole grain is carried out according to particle situation afterwards.
（9）：Fill encapsulated according to production technology after whole grain, in the qualified workshops of GMP, with automatic capsule agent according to the rules
Loading amount commissioning device after, according to technique start shooting it is encapsulated, product is checked at any time during loading amount, by the qualified product of loading amount
Polished in sanding machine, after big packaging, move to be tested qualified between keeping in.
The present invention due to said preparation by holothurian collagen Gly-His-Lys, ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder,
Medicinal zinc sulfate, selenide of carragheen composition, with reinforcing vital energy, strengthen immunity, discharging garbage from body, anti-aging, recovery are tired
The advantages of labor effect is significant.
Specific embodiment
A kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations, it is characterised in that said preparation by holothurian collagen Gly-His-Lys,
Ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal zinc sulfate, selenide of carragheen composition, the weight of above-mentioned each constituent
Part it is：10-30 parts of holothurian collagen Gly-His-Lys, ginseng powder 5-20 parts, seabuckthorn fruit powder 20-40 parts, G-protein 10-15 parts, Herba Cistanches
Powder 20-45 parts, medicinal zinc sulfate 3-10 parts, 0.01-0.05 part of selenide of carragheen, the weight optimized in described each composition
Than being 25-30 parts of holothurian collagen Gly-His-Lys, ginseng powder 14-17 parts, seabuckthorn fruit powder 22-38 parts, G-protein 11-14 parts, Herba Cistanches
Powder 30-38 parts, medicinal zinc sulfate 4-7 parts, 0.01-0.05 part of selenide of carragheen, the processing step of preparation method are as follows：（1）：
Holothurian collagen Gly-His-Lys：New fresh sea cucumber is cleaned first, is cut off, removing internal organ, reservation flow out containing sea cucumber self-dissolving
The liquid of enzyme, and the impurity in the sea cucumber intestine and sea cucumber in sea cucumber internal organ is cleared, and sea cucumber intestine and sea cucumber are standby in the lump, so
Ball milling mashing after afterwards crushing sea cucumber, sea cucumber intestine and sea cucumber, adds in enzymatic vessel, adds 5 ~ 10 times of sea cucumber raw material
Water, adds the liquid and appropriate food flavor enzyme of the enzyme containing sea cucumber self-dissolving of reservation, is well mixed, and opens steam cock, gradually
45 ~ 65 DEG C are warming up to, under conditions of being stirred continuously, constant temperature is maintained 3.5 ~ 4 hours, are treated that whole liquid is clarified substantially and is warming up to
100 DEG C, after 5 ~ 10 minutes, gained supernatant liquid adjustment concentration is 2% ~ 10% by cooling filtering, is then entered with clean spray drying tower
Row spray drying, after the assay was approved, polybag vacuumizes packaging to the spray powder of gained, and Cord blood is standby；(2) American Ginseng:Purchase
Buy the American Ginseng of qualified qualification unit, together with the laboratory test report of the unit, send inspection center according to《Chinese Pharmacopoeia》Version is entered within 2015
Performing check.The qualified raw material of inspection is taken, is added water with JYL-5 broken wall cooking machines and carry out broken wall treatment in right amount, with pressure 0.09MP temperature
Degree control after ORW105 microwave vacuum dryers are dried, is crushed at 40 degree with qualified stainless steel pulverizer, reaches 150 mesh.Water
Divide≤5%, save backup；（3）Sea-buckthorn：Inspection center is sent to check the sea-buckthorn fine powder bought in qualified unit, an inspection refers to
Mark is qualified, is added water with JYL-5 broken wall cooking machines and carry out broken wall treatment in right amount, with pressure 0.09MP temperature controls at 40 degree,
After ORW105 microwave vacuum dryers are dried, then by seabuckthorn fruit powder dried process after, carry out powder with clean stainless steel pulverizer
It is broken, 120 eye mesh screens are then crossed, it is standby after gained powder-tight is packed；（4）G-protein：Purchase has the angle swallow G eggs of qualification unit
In vain, together with unit laboratory test report of selling goods, inspection center is sent to check, then JYL-5 broken wall cooking machines add water and carry out broken wall treatment in right amount, use
Pressure 0.09MP temperature controls after ORW105 microwave vacuum dryers are dried, are crushed at 40 degree with qualified stainless steel pulverizer,
120 mesh sieves are crossed, moisture≤5% is packed rear standby；（5）Saline cistanche：The saline cistanche that will be bought in qualified unit, censorship
Center inspection is tested, test rating is qualified, then saline cistanche is added water with JYL-5 broken wall cooking machines carry out broken wall treatment in right amount, use
Pressure 0.09MP temperature controls after ORW105 microwave vacuum dryers are dried, are carried out at 40 degree with clean stainless steel pulverizer
Crush, then cross 120 eye mesh screens, it is standby after gained powder-tight is packed；（6）：Take selenide of carragheen, medicinal zinc sulfate, send
Inspection center inspection is qualified, then after selenide of carragheen and zinc sulfate are separately dried, and is put into the stainless steel pulverizer of cleaning
Row is crushed, and then crosses 100 eye mesh screens, standby after gained powder-tight is packed；（7）According to recipe requirements, by sea cucumber collagen egg
White Gly-His-Lys, ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal zinc sulfate, selenide of carragheen, put three-dimensional mixer abundant
Mix,（8）Granulation and arrangement grain：According to granulating process, 60-70% alcohol granulations are used, be dried at a temperature of 80-90 degree, so
Whole grain is carried out according to particle situation afterwards；（9）：Fill encapsulated according to production technology after whole grain, in the qualified workshops of GMP, with certainly
After loading amount commissioning device of the dynamic capsule according to regulation, started shooting according to technique encapsulated, check product at any time during loading amount,
The qualified product of loading amount is polished in sanding machine, after big packaging, moves to be tested qualified between keeping in.
Constituent analysis in the present invention
Holothurian collagen Gly-His-Lys：Sea cucumber, sweet-salty, kidney tonifying, benefiting quintessence takes the photograph urine, and impotence, its benefit warm in nature, sufficient enemy are treated in establishing-Yang
Ginseng, therefore named sea cucumber；Sea cucumber have improve memory, delay sexual gland aging, prevent artery sclerosis and it is antitumor wait act on.
Ginseng powder：It is cool in nature, sweet, slight bitter；Indication：Boosting qi and nourishing yin, clearing heat and promoting fluid.For deficiency of vital energy yin deficiency, interior heat,
Cough and asthma phlegm blood, abnormal heat is tired of tired, quenches one's thirst that the dry larynx of mouth is done.3~6g of consumption.Beneficial lung yin, the clear fire of deficiency type, promotes the production of body fluid to quench thirst.The deficiency syndrome of the lung is controlled to cough long,
Lose blood, dry throat and mouth, abnormal heat is tired of tired.
Seabuckthorn fruit powder：Effect has preventing and treating cardiovascular and cerebrovascular disease：Total seabuckthorn flavone, unrighted acid extracted from sea-buckthorn etc.
Composition can effectively adjust blood pressure, blood fat, blood sugar, directly remove superoxide radical and hydroxy radical, reduce blood viscosity, suppress blood
Platelet is excessively assembled, softening blood vessel, improve blood circulation, prevent artery sclerosis, to coronary heart diseases and angina pectoris, miocardial infarction, the rhythm of the heart
The illnesss such as not normal, myocardial ischemia-anoxemia have fabulous preventive and therapeutic effect, in addition to improving heart function, alleviating uncomfortable in chest, palpitaition, shortness of breath etc.
Symptom also plays the role of fabulous；Auxiliary treatment diabetes, the active ingredient extracted from sea-buckthorn（Hippophate flavone, vitamin, mineral
Matter, trace element, SOD etc.）Blood sugar, the state of an illness of stabilization diabetes can be reduced；Enhancing immune function of human body, containing a large amount of in sea-buckthorn
Vitamin C, vitamin E, carotenoid, SOD, Hippophate flavone all have very strong antioxidation.To humoral immunity and carefully
Born of the same parents are immune to have obvious adjustment effect, also certain anti-allergic effects, enhancing human disease resistance, these active ingredient energy
Human free radical is removed, body's immunity effect is improved, thus clinic is to panimmunity systemic disease such as immunologic hypofunction
Acted on very well etc. having.The other adjustable thyroid function in Hippophate flavone sea, makes hyperthyroidism recover normal；Antitumor,
Antitumaous effect；The white anthocyanidin of bioactive ingredients, guassin, cumarin, serotonin, bata-carotene in sea-buckthorn etc. have bright
Aobvious antioxidant effect.There is certain suppression and lethal effect to the cancer cell in human body, also with the work of blocking carcinogenic factor
With.And can by improving the autoimmune function of cancer patient, enhancing human body to the resistivity of cancer, especially to stomach
The cancer effect of the digestive systems such as cancer, cancer of the esophagus, the carcinoma of the rectum, liver cancer is quite obvious.The poison that radiotherapy and chemotherapy can be mitigated in addition is secondary
Effect, promotes cancer patient's rehabilitation；Anti- treating respiratory system disease, sea-buckthorn just has relieving cough and asthma, profit in traditional medical theory
The effect of lung resolving sputum, has very to respiratory tract system diseases such as chronic pharyngitis, bronchitis, abscess of throat, asthma, cough ant phlegms
Good effect；Liver protecting, prevents and treats liver diseases, the organic acid such as the malic acid contained in sea-buckthorn, oxalic acid have alleviate antibiotic and
The toxic action of other drugs, promotes impaired stem cell to accelerate healing, reduces transaminase, protects liver.Simultaneously to liver pair
In fat there is elimination to act on.There is obvious mitigation to acute liver disease, chronic liver disease, alcoholic liver, fatty liver, cirrhosis.
In addition, Seabuckthorn Oil has significant protective effect to kidney and marrow；Disease of digestive system is prevented and treated, it is big due to containing in sea-buckthorn
The multiple nutritional components such as amount amino acid, organic acid, can promote hydrochloric acid in gastric juice, gastric secretion thus sea-buckthorn has relieving dyspepsia, invigorating the spleen
Nourishing the stomach, the effect of dispersing stagnated hepatoqi.For indigestion, abdominal distention and pain, gastritis, gastric and duodenal ulcer, enteritis, chronic constipation etc.
Play the role of fabulous；Ophthalmology disease is prevented and treated, is contained in sea-buckthorn and is whether there is hydroxytryptamine with very strong radiation resistance.The former Soviet Union is husky
Spine oil lists the necessary health products of astronaut in.There is remarkable result to preventing and treating all kinds of ophthalmology diseases.Trachoma, eyeball can be treated with it
Flajani's disease, keratitis, bubble, eyelid burn and conjunctivitis etc.；Hemostatic analgesia, anti-inflammation detumescence, removing necrosis, promoting granulation treatment
Various gynecological diseases, the Seabuckthorn Oil extracted in sea-buckthorn is rich in VE, carrotene, carotenoid, cupreol, unrighted acid
Deng, body metabolism can be promoted, be conducive to the organized renewing for damaging, strengthen the antiinflammatory action at inflammation center, and significantly
Promote ulcer healing effect.Thus Seabuckthorn Oil clinically to radiation injury, burn, scald, dermatitis, catarrh, canker sore,
Endometritis, cervical erosion and stomach and pain, reduction adverse reaction, also there is effect very well；It is brain tonic and intelligence development, beauty and skin care, anti-ageing
Always, several amino acids, multivitamin, trace element, unrighted acid, SOD for containing in sea-buckthorn etc. are old to preventing skin
Change, desalination senile plaque expelling, chloasma, improve the health care of sleep quality, improve memory, keep vigorous energy and the muscle power to have good work
With.
G-protein：Refer to that can be combined with guanylic acid, the class signal transducer with GTP hydrolytic enzyme activities.G
The signal transduction pathway that albumen is participated in is a kind of very conservative transmembrane signal transduction mechanism in animal and plant body.Work as cell transduction
During extracellular signal, extracellular various aglucons (extracellular first letter is received by different types of g protein coupled receptor (GPCRs) first
Make).Then acceptor is activated, further the Heterotrimeric G-Protein on the inside of activation plasma membrane, and it is various that the latter deactivates downstream again
Effector, produces intracellular second messenger.So as to signal be handed on step by step, the growth and development process of organism is adjusted.
Saline cistanche powder：It is sweet；It is salty；It is warm in nature；Return through；Return kidney；Large intestine channel；Indication：Kidney-replenishing；Benefiting essence-blood；Ease constipation road.
Main decline of kidney-YANG；The impotence of asthenia of essence and blood；Seminal emission；Gonorrhoea；The frequent micturition heeltap；Pain in the back flaccidity of lower limbs；Tinnitus mesh is spent；Menstruation is spread out the phase；Gong Han
It is infertile；Dry constipation of intestines.
Selenide of carragheen：The universal immunologic hypofunction of hepatopath, its most obvious performance is exactly that internal virus is difficult to
It is fully erased, the easy recurrent exerbation of the state of an illness.And the main component selenide of carragheen of liver gold is potent immunosuppressant conditioning agent, can stimulate
Immunity system, strengthens the immunologic function of body, the resistance against diseases of liver itself is improved, so as to help to prevent liver disease
Recurrent exerbation.In addition, the enhancing of immunologic function, is conducive to improving the various symptoms of hepatopath, such as hepatitis A, B patient
Mending selenide of carragheen can substantially improve the symptoms such as anorexia, weak, face be dark and gloomy within the relatively short time.
Embodiment 1
11 parts of holothurian collagen Gly-His-Lys, 7 parts of ginseng powder, 23 parts of seabuckthorn fruit powder, 14 parts of G-protein, 24 parts of Herba Cistanches powder, medicinal sulphur
5 parts of sour zinc, 0.02 part of selenide of carragheen.
Embodiment 2
It is 27 parts of holothurian collagen Gly-His-Lys, 18 parts of ginseng powder, 38 parts of seabuckthorn fruit powder, 14 parts of G-protein, 42 parts of Herba Cistanches powder, medicinal
9 parts of zinc sulfate, 0.05 part of selenide of carragheen.
Embodiment 3
It is 22 parts of holothurian collagen Gly-His-Lys, 17 parts of ginseng powder, 34 parts of seabuckthorn fruit powder, 14 parts of G-protein, 26 parts of Herba Cistanches powder, medicinal
9 parts of zinc sulfate, 0.04 part of selenide of carragheen.
Embodiment 4
It is 14 parts of holothurian collagen Gly-His-Lys, 16 parts of ginseng powder, 33 parts of seabuckthorn fruit powder, 14 parts of G-protein, 26 parts of Herba Cistanches powder, medicinal
7 parts of zinc sulfate, 0.03 part of selenide of carragheen.
Embodiment 5
It is 28 parts of holothurian collagen Gly-His-Lys, 17 parts of ginseng powder, 32 parts of seabuckthorn fruit powder, 13 parts of G-protein, 34 parts of Herba Cistanches powder, medicinal
9 parts of zinc sulfate, 0.05 part of selenide of carragheen.
Crowd's test-meal result
1. 110 patients are tracked, this 110 patients, immunity is low, usually once restoring a reactionary rule, be easy for generation and catch a cold and adjoint
Fever, and resistance is substantially low, takes this product three months or so, and resistance is significantly improved, and treats bad weather change
Change is not easy to catch a cold, wherein, without flu, 10 patient's times of common cold are significantly reduced for 92 patient's wintry weather changes,
The flu healing cycle substantially reduces, 8 patient's times of common cold reductions, cures by typically taking medicine.
2. Lee, man, 70 years old, physical function was gradually reduced, symptom of having a pain in the back substantially, delay of response, poor memory, skin
Skin relaxes, lackluster, and through taking product of the present invention 5 months afterwards, muscle power is remarkably reinforced, good appetite, have rosy cheeks, it is seen that this
Invention product can the strong vital organs of the human body, can alleviate or release various chronic diseases marked by deficiency of vital energy symptoms, comprehensively enhancing human body constitution anti-aging.
3. Cao, female, 56 years old, postoperative resistance was substantially reduced, meanwhile, feel fatigue weak, after taking this product half a year,
Substantially feel fresh, vigour increases, have rosy cheeks, immunity is improved, relatively the patient of stage operation compares simultaneously, Ren recovers
Constitution is very fast, while sick body recovers preferable.
4. certain is relied, man, 50 years old, operating pressure was big, poor sleeping quality, after taking this product, two months, three times a day, nothing
Sense of fatigue, energetic, job enthusiasm.
The present invention due to said preparation by holothurian collagen Gly-His-Lys, ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder,
Medicinal zinc sulfate, selenide of carragheen composition, with reinforcing vital energy, strengthen immunity, discharging garbage from body, anti-aging, recovery are tired
The advantages of labor effect is significant.
Claims (3)
1. a kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations, it is characterised in that said preparation by holothurian collagen Gly-His-Lys, west
American ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal zinc sulfate, selenide of carragheen composition, the weight portion of above-mentioned each constituent
For：10-30 parts of holothurian collagen Gly-His-Lys, ginseng powder 5-20 parts, seabuckthorn fruit powder 20-40 parts, G-protein 10-15 parts, Herba Cistanches powder
20-45 parts, medicinal zinc sulfate 3-10 parts, 0.01-0.05 part of selenide of carragheen.
2. a kind of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparations according to claim 1, it is characterised in that it is described it is each into
The weight ratio optimized in point is 25-30 parts of holothurian collagen Gly-His-Lys, ginseng powder 14-17 parts, seabuckthorn fruit powder 22-38 parts, G eggs
White 11-14 parts, 30-38 parts of Herba Cistanches powder, medicinal zinc sulfate 4-7 parts, 0.01-0.05 part of selenide of carragheen.
3. a kind of preparation method of double ginseng sea-buckthorn G-protein saline cistanche zinc selenium preparation, it is characterised in that the processing step of preparation method
It is as follows：
（1）：Holothurian collagen Gly-His-Lys：New fresh sea cucumber cleaned first, is cut off, removing internal organ, what reservation was flowed out contains sea
Join the liquid of the enzyme of self-dissolving, and the impurity in the sea cucumber intestine and sea cucumber in sea cucumber internal organ is cleared, sea cucumber intestine and sea cucumber one
And standby, ball milling mashing after then crushing sea cucumber, sea cucumber intestine and sea cucumber, add in enzymatic vessel, add the 5 of sea cucumber raw material
~ 10 times of water, adds the liquid and appropriate food flavor enzyme of the enzyme containing sea cucumber self-dissolving of reservation, is well mixed, and opens steam and opens
Close, 45 ~ 65 DEG C are warming up to gradually, under conditions of being stirred continuously, maintain constant temperature 3.5 ~ 4 hours, treat that whole liquid is clarified substantially
100 DEG C, after 5 ~ 10 minutes are warming up to, gained supernatant liquid adjustment concentration is 2% ~ 10%, then with clean spray by cooling filtering
Dry tower is spray-dried, and after the assay was approved, polybag vacuumizes packaging to the spray powder of gained, and Cord blood is standby；
(2) American Ginseng:Buy the American Ginseng of qualified qualification unit, together with the laboratory test report of the unit, send inspection center according to《China
Pharmacopeia》Version is tested within 2015.The qualified raw material of inspection is taken, is added water with JYL-5 broken wall cooking machines and carry out broken wall treatment in right amount,
With pressure 0.09MP temperature controls at 40 degree, after ORW105 microwave vacuum dryers are dried, with qualified stainless steel pulverizer powder
It is broken, reach 150 mesh.Moisture≤5%, saves backup.
（3）Sea-buckthorn：Send inspection center to check the sea-buckthorn fine powder bought in qualified unit, a test rating is qualified, use
JYL-5 broken wall cooking machines add water and carry out broken wall treatment in right amount, with pressure 0.09MP temperature controls in 40 degree, ORW105 microwave vacuums
After drying machine is dried, then by seabuckthorn fruit powder dried process after, crushed with clean stainless steel pulverizer, then cross 120 mesh
Screen cloth, it is standby after gained powder-tight is packed；
（4）G-protein：Purchase has the angle swallow G-protein of qualification unit, together with unit laboratory test report of selling goods, send inspection center to check,
JYL-5 broken walls cooking machine adds water and carry out broken wall treatment in right amount again, and with pressure 0.09MP temperature controls at 40 degree, ORW105 is micro-
After ripple vacuum drier is dried, crushed with qualified stainless steel pulverizer, cross 120 mesh sieves, moisture≤5% packs standby
With.
（5）Saline cistanche：The saline cistanche that will be bought in qualified unit, send inspection center to check, and test rating is qualified, then will
Saline cistanche is added water with JYL-5 broken wall cooking machines and carry out broken wall treatment in right amount, with pressure 0.09MP temperature controls in 40 degree, ORW105
After microwave vacuum dryer is dried, crushed with clean stainless steel pulverizer, 120 eye mesh screens are then crossed, by gained powder
Pack rear standby；
（6）：Take selenide of carragheen, medicinal zinc sulfate, to send inspection center to check qualified, then selenide of carragheen and zinc sulfate are distinguished
After drying, be put into cleaning stainless steel pulverizer in crushed, then cross 100 eye mesh screens, by gained powder-tight pack after
It is standby；
（7）According to recipe requirements, by holothurian collagen Gly-His-Lys, ginseng powder, seabuckthorn fruit powder, G-protein, Herba Cistanches powder, medicinal sulphur
Sour zinc, selenide of carragheen, put three-dimensional mixer and fully mix,
（8）Granulation and arrangement grain：According to granulating process, 60-70% alcohol granulations are used, be dried at a temperature of 80-90 degree, so
Whole grain is carried out according to particle situation afterwards.
（9）：Fill encapsulated according to production technology after whole grain, in the qualified workshops of GMP, with automatic capsule agent according to the dress for specifying
After amount commissioning device, started shooting according to technique encapsulated, product is checked at any time during loading amount, by the qualified product of loading amount in mill
Polished in ray machine, after big packaging, move to be tested qualified between keeping in.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109463757A (en) * | 2018-12-01 | 2019-03-15 | 河北御品源企业管理服务有限公司 | A kind of preparation method of sea cucumber peptide seabuckthorn fruit powder |
| CN109480235A (en) * | 2018-12-01 | 2019-03-19 | 河北御品源企业管理服务有限公司 | A kind of sea cucumber peptide sea-buckthorn tabletting and preparation method thereof |
| CN109527587A (en) * | 2019-01-03 | 2019-03-29 | 拓普河北生物科技有限公司 | A kind of collagen Gly-His-Lys and preparation method thereof with senile-resistant efficacy |
| CN114041605A (en) * | 2021-11-17 | 2022-02-15 | 浙江诺衍生物科技有限公司 | Composition for regulating male hormone and sexual function and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102934797A (en) * | 2012-10-26 | 2013-02-20 | 青岛佳日隆海洋食品有限公司 | Trepang capsule and preparation process thereof |
| CN102940247A (en) * | 2012-10-26 | 2013-02-27 | 青岛佳日隆海洋食品有限公司 | Sea cucumber capsule and preparation process thereof |
| CN104351612A (en) * | 2014-11-21 | 2015-02-18 | 威海力元海洋生物科技有限公司 | Sea cucumber, lucid ganoderma, glucan and selenium preparation and preparation method thereof |
| CN105595224A (en) * | 2015-12-30 | 2016-05-25 | 威海力元海洋生物科技有限公司 | Sea cucumber dunaliella salina glucosan selenium preparation and preparation process |
-
2016
- 2016-11-14 CN CN201610998387.3A patent/CN106723075A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102934797A (en) * | 2012-10-26 | 2013-02-20 | 青岛佳日隆海洋食品有限公司 | Trepang capsule and preparation process thereof |
| CN102940247A (en) * | 2012-10-26 | 2013-02-27 | 青岛佳日隆海洋食品有限公司 | Sea cucumber capsule and preparation process thereof |
| CN104351612A (en) * | 2014-11-21 | 2015-02-18 | 威海力元海洋生物科技有限公司 | Sea cucumber, lucid ganoderma, glucan and selenium preparation and preparation method thereof |
| CN105595224A (en) * | 2015-12-30 | 2016-05-25 | 威海力元海洋生物科技有限公司 | Sea cucumber dunaliella salina glucosan selenium preparation and preparation process |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109463757A (en) * | 2018-12-01 | 2019-03-15 | 河北御品源企业管理服务有限公司 | A kind of preparation method of sea cucumber peptide seabuckthorn fruit powder |
| CN109480235A (en) * | 2018-12-01 | 2019-03-19 | 河北御品源企业管理服务有限公司 | A kind of sea cucumber peptide sea-buckthorn tabletting and preparation method thereof |
| CN109527587A (en) * | 2019-01-03 | 2019-03-29 | 拓普河北生物科技有限公司 | A kind of collagen Gly-His-Lys and preparation method thereof with senile-resistant efficacy |
| CN114041605A (en) * | 2021-11-17 | 2022-02-15 | 浙江诺衍生物科技有限公司 | Composition for regulating male hormone and sexual function and application thereof |
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