CN106680471A - Biochip detection system - Google Patents
Biochip detection system Download PDFInfo
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- CN106680471A CN106680471A CN201611234353.3A CN201611234353A CN106680471A CN 106680471 A CN106680471 A CN 106680471A CN 201611234353 A CN201611234353 A CN 201611234353A CN 106680471 A CN106680471 A CN 106680471A
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- plate
- shelve
- enrichment
- image capturing
- mounting seat
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
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- Life Sciences & Earth Sciences (AREA)
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- Hematology (AREA)
- General Physics & Mathematics (AREA)
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- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
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- General Health & Medical Sciences (AREA)
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- Cell Biology (AREA)
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- Food Science & Technology (AREA)
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a biochip detection system, comprising a biochip detection device and an enrichment device for collecting biological samples. The biochip detection system is characterized in that the biochip detection device comprises a support frame, wherein an image capture mechanism, a biochip loading mechanism and a light source mechanism are arranged on the support frame, the image capture mechanism is arranged in front of the biochip loading mechanism, and the light source mechanism is arranged behind the biochip loading mechanism; and the enrichment device comprises an enrichment box which is detachably arranged on the support frame, a storage cavity is arranged in the enrichment box, and a hybridization reagent, a hybridization box and a biochip are taken in the storage cavity. The biochip detection system has the advantages that the enrichment box for collecting the biological samples is detachably arranged on the support frame, the storage cavity is arranged in the enrichment box, and the hybridization reagent, the hybridization box and the biochip related to detection are arranged in the storage cavity, and all the devices for detection are integrated together orderly, so that the biochip detection system is small in volume, convenient to move, simple in structure, and convenient to use.
Description
Technical field
The present invention relates to biochip test field, more particularly, to a kind of biological chips detection system.
Background technology
Biochip（Biochip or bioarray）It is according to the special principle for interacting between biomolecule, by biochemistry
Process integration is analyzed in chip surface, so as to realize the high flux to DNA, RNA, polypeptide, protein and other biological composition
Quick detection.The biochip concept of narrow sense is referred to biomolecule by distinct methods（Oligonucleotide, cDNA, genomic
DNA, polypeptide, antibody, antigen etc.）It is bonded to silicon chip, sheet glass（Pearl）, plastic sheet（Pearl）, gel, in the solid phase mediator such as nylon membrane
The biomolecule dot matrix of formation.The concept of chip takes from integrated concept, and biochip is the integrated of biomaterial.As experiment
Room detection is the same, and blood glucose, albumen, enzymatic activity etc. are checked on biochip, is based on same biological respinse principle.So raw
Thing chip is exactly a carrier platform, is a carrier, is in base by discontinuous analysis process integration in life science
The miniature biochemical analysis system on piece surface, to realize to the accurate, fast of cell, protein, gene and other biological components
Speed, the detection of large information capacity.The technical advantage that biochip possesses makes detection quicker, sensitive and accurate.Conventional biology
Chip detection needs to use the equipment such as nucleic acid augmentative instrument, chip hybridization instrument, chip cleaner and detector.In the market upper
State a whole set of related equipment not only expensive, and volume is big and heavy, unsuitable Jing is often moved, and it is larger to move difficulty.
The content of the invention
The technical problem to be solved is to provide a kind of small volume and is easy to mobile biological chips detection system.
The present invention solve the technical scheme that adopted of above-mentioned technical problem for：
A kind of biological chips detection system, including bio-chip test device and the enriching apparatus for biological specimen collection, institute
The bio-chip test device stated includes support, and image capturing mechanism, biochip loader mechanism are provided with described support
And light source mechanism, described image capturing mechanism is arranged on before described biochip loader mechanism, described light source mechanism
After being arranged on described biochip loader mechanism；Described enriching apparatus include enrichment box, and described enrichment box is detachable
Be arranged on described support, object placing cavity is provided with described enrichment box, described glove intracavity storage is provided with hybridization
Reagent, hybridizing box and biochip.
Described support include being shelved on vertically arranged plate and under shelve plate, it is described on shelve plate can up and down adjustably
Be arranged on it is described under shelve the top of plate, it is described on shelve the front end face of plate with it is described under shelve plate front end face it is neat
It is flat, it is described on shelve the both sides of plate and be respectively arranged with the upper side shield for extending forward, it is described under shelve the both sides difference of plate
Being extended forward has a lower side shield, described upper side shield and described downside baffle position up and down with respect to and described upside
The inner side end of baffle plate is flushed with the inner side end of described lower side shield, it is described under shelve the bottom of plate and be extended forward
Have a horizontal lower location-plate, described upper side shield, lower side shield, on shelve plate, under shelve plate and described lower location-plate it
Between enclose and be set as one and shelve chamber.Above-mentioned supporting structure is simple, easily manufactured, above shelves plate and can adjustably be arranged on down up and down and shelves
On plate so that the support can be adapted to the mobile phone of different length, lower location-plate plays a part of lower positioning to mobile phone, it is ensured that mobile phone
Can stably be seated on support.
The first vertical guide chute is provided with described upper side shield, in the first described guide chute downslide can be gone up
The first lead column is provided with dynamicly, is connected with height regulating rod below the first described lead column, described upper side shield
Lower surface is provided with height adjusting holes, and the vertical centrage of described height adjusting holes is vertical with the first described guide chute
Centrage coincides, and described height adjusting holes are connected with the first described guide chute, described height regulating rod
Stretch out described height adjusting holes and be fixedly installed on described lower side shield in bottom.Led by the first guide chute and first
To the cooperation of post, the motion to height regulating rod play the guiding role.
The internal diameter of described height adjusting holes is more than the external diameter of described height regulating rod and less than the first described guiding
The external diameter of post.The internal diameter of height adjusting holes is less than the external diameter of the first lead column more than the external diameter of height regulating rod, it is ensured that height is adjusted
Pole can be swimmingly up and down and can be stably mounted to shelve on plate.
The front end face of described upper side shield is provided with internal thread hole, and described internal thread hole is slided with the first described guiding
Groove is connected, and on described internal thread hole lock-screw is bolted with, by lock-screw by the position of described height regulating rod
It is locked.The front end face of upper side shield is provided with internal thread hole, and lock-screw is bolted with internal thread hole, above shelves the height of plate
After the completion of degree is adjusted, the position of height regulating rod is fixed by tightening lock-screw.
Described image capturing mechanism includes the mobile phone with camera function and image capturing plate, and described mobile phone is shelved on institute
That what is stated shelves intracavity, it is described on shelve the image capturing window that before and after insertion is provided with plate, described image capturing plate can
Slidingly be arranged on described image capturing window, the front end face of described image capturing plate with it is described under shelve plate
Front end face flush, be provided with the image capturing hole of before and after insertion on described image capturing plate, described biochip is loaded
Mechanism is located at the rear in described image capturing hole.Above-mentioned image capturing mechanism simple structure, it is easy to operate, shelve plate upper
The image capturing window of insertion before and after upper setting, can slidingly arrange one with image capturing hole on image capturing window
Image capturing plate, the mobile phone that photographic head is arranged on diverse location is adapted to by the position of left and right adjusting image capturing plate, specifically
When using, mobile phone is put to be shelved on and shelves intracavity, adjust image capturing plate right position and on shelve the upper-lower position of plate,
The photographic head on mobile phone is set to be directed at image capturing hole, and on lower location-plate, then the bottom of mobile phone stably can be shelved on
Bio information on the biochip loaded on biochip loader mechanism is captured by the mobile phone with camera function.
Two inner faces up and down of described image capturing window are provided with and are engaged with described image capturing plate thickness
Chute, described image capturing plate is slidably disposed in described chute, it is described on shelve the upper surface of plate and arrange
There is vertical locking hole, described locking hole is connected with the chute on described image capturing window upper interior end face, described
Locking hole on be bolted with a lock-screw, the position of described image capturing plate is fixed by described lock-screw.
Horizontally slipping for image capturing plate is realized by the chute being engaged with image capturing plate thickness, different camera positions can be adapted to
Mobile phone, simple structure is easy to operate.
The clamp system being provided with plate for mobile phone to be fixedly clamped is shelved under described, described clamp system includes
Width adjusting bar and clamping plate, it is described on shelve the front end face of plate and be provided with the groove being recessed backward, it is described under shelve plate
The second horizontal guide chute is inside provided with, the second lead column can be slidingly provided with the second described guide chute,
Horizontal back-moving spring, described groove are provided between described the second lead column and the second described guide chute side end face
Side end face on be provided with width adjusting hole, the cross central line and the second described guide chute in described width adjusting hole
Cross central line overlaps, and described width adjusting hole is connected with the second described guide chute, described width adjusting bar
One end is stretched into described width adjusting hole and is connected with the second described lead column, and described clamping plate is fixedly installed on described
The other end of width adjusting bar.Above-mentioned clamp system causes mobile phone to be shelved on when shelving intracavity, and right position can also obtain standard
It is determined that position, by the motion of the second guide chute and the second lead column to width adjusting bar guide effect is played, back-moving spring is given
One tightening force of clamping plate, simple structure is easy to operate, and clamps stable.
The internal diameter in described width adjusting hole is more than the external diameter of described width adjusting bar and less than the second described guiding
The external diameter of post.The internal diameter in width adjusting hole is more than the external diameter of width adjusting bar and less than the external diameter of the second lead column so that width
Adjusting rod can swimmingly horizontally slip and with a stable positioning.
With described clamping plate pull out direction it is consistent described in lower side shield on be provided with and described clamping plate
The opening being engaged, with described clamping plate pull out it is in opposite direction described in the inner face of lower side shield be provided with protection
Pad.Arrange on the consistent lower side shield in direction opening pulling out with clamping plate, the opening facilitates the operation of clamp system,
And neonychium is set in the inner face that lower side shield in opposite direction is pulled out with clamping plate, the neonychium is then to the side of mobile phone
Portion shields.
Described biochip loader mechanism includes load frame and load frame mounting seat, sets in described load frame
The rectangular watch window of before and after insertion is equipped with, be engaged with biochip is vertically provided with described load frame
One slot, described biochip inserts the detection sample position being arranged in the first described slot and on described biochip
In described watch window；The cylindric inner chamber of before and after insertion, described dress are provided with described load frame mounting seat
Carry the second slot being engaged with described load frame that up/down perforation is provided with framework mounting seat, described load frame
Insertion is arranged in the second described slot；Described load frame mounting seat is arranged on the rear end face of described image capturing plate
On, described cylindric inner chamber is coaxial with described image capturing hole, described image capturing hole and described cylindric inner chamber
Between be provided with lens.Load frame simple structure, the first slot is used to make biochip insert in it, provides to biochip
One stable installation positioning, watch window is easy to observation；The second slot arranged in load frame mounting seat is used to insert dress
Carry framework, cylindric inner chamber is coaxial with image capturing hole, it is ensured that by image capturing hole can accurate observation on biochip
Bio information, lens are set between image capturing hole and cylindric inner chamber, by lens by the biology letter on biochip
Breath amplifies, and is easy to mobile phone to capture more clearly biometric image.
The front end face of described load frame mounting seat is provided with the cylindric installation cavity for mounted lens, described
Cavity is installed with described cylindric coaxial and the internal diameter of described installation cavity is more than described cylindric inner chamber
Internal diameter, the size of described lens is closed with the matching size of described installation cavity.The installation arranged in load frame mounting seat
Cavity is used to provide a stable installation positioning to lens, installs cavity with cylindric coaxial so that lens can be compared with
The effect for amplifying the bio information on biochip is played well, the internal diameter of the internal diameter more than cylindric inner chamber of cavity is installed, thoroughly
The size of mirror is closed with the matching size for installing cavity so that lens can be stably mounted to install in cavity, it is to avoid lens are fallen into
Affect normally to use in cylindric inner chamber.
The position adjusting mechanism for adjusting load frame upper-lower position is provided with described load frame mounting seat.It is logical
Cross position adjusting mechanism and adjust upper-lower position of the load frame in load frame mounting seat, so that the life on biochip
Thing information can obtain complete capture.
Described position adjusting mechanism includes the regulation internal gear for cooperating and adjusts external gear, described load frame
Mounting seat includes the columned front pedestal being coaxially disposed and rear pedestal, and the external diameter of described front pedestal is more than described rear pedestal
External diameter, the second described slot is arranged on described front pedestal, and the sidepiece of described load frame mounting seat is circumferentially equal
Cloth is provided with least two depressed parts, described depressed part and described cylindric intracavity inter-connection, described regulation external gear
It is rotatably arranged in described depressed part, two lateral surface of described load frame are provided with and described regulation external tooth
The tooth bar that wheel is engaged, described regulation inner gear housing is located on described rear pedestal and with described regulation external gear mutually to be nibbled
Close, described load frame insertion is arranged in the second described slot and described tooth bar is mutually nibbled with described regulation external gear
Close, the rear portion of described rear pedestal is coaxially disposed restraining position ring block.Above-mentioned position adjusting mechanism, simple structure is easy to operate, rear base
Seat adjusts external gear for installing, and a front limit and rear limit are provided to the installation for adjusting internal gear by front pedestal and spacing ring
Position, it is ensured that adjust the stable installation of internal gear, rotates during regulation and adjusts internal gear, drives the regulation external tooth rotation being meshed therewith
It is dynamic, drive the tooth bar being meshed with the regulation external gear to move up and down, so that load frame is transported up and down along the second slot
Dynamic, the upper-lower position for realizing load frame is adjusted.
The sidepiece of described rear pedestal is provided with the 3rd slot of insertion, and the 3rd described slot is inserted into being provided with astigmatism
Piece.Scattering sheet is inserted in the 3rd slot, the equalizing light rays that can be emitted light source mechanism are easy to enter biochip
Row is clearly viewed.
External diameter of the external diameter of described spacing ring more than described rear pedestal.The external diameter of spacing ring is outer more than rear pedestal
Footpath, it is ensured that spacing ring plays stable rear position-limiting action.
Anti-slop serrations have been uniformly arranged on the lateral wall of described regulation internal gear.The setting of anti-slop serrations can increase regulation internal tooth
The frictional force of wheel lateral wall, is easy to carry out rotating operation to it.
Described light source mechanism includes light source, driving power supply, light source mounting seat and driving power supply mounting seat, described light source
Mounting seat is fixedly mounted on the rear end of described spacing ring, be provided with described light source mounting seat before and after insertion and with it is described
Cylindric coaxial printing opacity chamber, described light source is arranged on described printing opacity intracavity, and the rear end of described light source is arranged
There is the power supply conduction panel electrically connected with described light source, described driving power supply is arranged in described driving power supply mounting seat,
Described driving power supply mounting seat is arranged on the rear of described light source mounting seat, and triggering is provided with described driving power supply
Plate, described trigger board is electric when described trigger board is contacted with described power supply conduction panel just to described power supply conduction panel
Source conducting makes described light source luminescent.Above-mentioned light source mechanism simple structure, by light source mounting seat and driving power supply mounting seat point
Not Gei light source and driving power supply one stable installing space is provided, by the separation between power supply conduction panel and trigger board and connect
Closing and the opening for realizing light source is touched, it is simple to operate, it is easy to use.
The rear end of described light source mounting seat is provided with externally threaded mounting ring, under unused state, described driving
In described mounting ring, described trigger board is separated power supply mounting seat screwing sections with described power supply conduction panel, uses
When, screwing described driving power supply mounting seat makes described trigger board contact with described power supply conduction panel, described light source
It is luminous.Said structure can not only be stably mounted to driving power supply mounting seat in light source mounting seat, while electricity can be realized quickly
Separate between source conduction panel and trigger board and contact, simple structure is easy to operate.
The lateral part of described driving power supply mounting seat has been uniformly arranged anti-slop serrations.The setting of anti-slop serrations can increase driving electricity
The frictional force of source mounting seat lateral wall, is easy to carry out rotating operation to it.
Described lower side shield extends back and is provided with adjutage.Adjutage is played a supporting role to whole support.
The support feet for supporting described support is provided with described adjutage.Support feet is provided with adjutage
Further function as the supporting role to whole support so that whole support is stabilized support.
Described support feet support angle is adjustable and can move up and down along described adjutage.Support feet adjustable angle and can
Move up and down along adjutage so that the support angle of support is adjustable, is easy to the mobile phone to being shelved on support to operate.
Described enriching apparatus also include enrichment test tube, and described enrichment box includes base plate, top board, backboard and two sides
Plate, described floor level is arranged, and the side plate described in two is vertically provided at respectively the both sides of described base plate, described backboard
It is vertically provided on described base plate and the both sides of described backboard is connected respectively with the side plate described in two, described top board
Both sides can be arranged on respectively on the inner side end of the side plate described in two pull, described base plate, top board, backboard and two
The cavity for being set as a front opening is enclosed between side plate, one is horizontally arranged with described cavity and is shelved plate, described shelves plate
Both sides be connected with the side plate described in two respectively, it is described to shelve vertically arranged by one between plate and described base plate
Gripper shoe is connected, described shelving be provided with plate it is multiple be engaged with described enrichment test tube shelve through hole, it is described
Enrichment test tube be shelved on it is described shelve in through hole, immunomagnetic beadses are provided with described enrichment test tube, in described gripper shoe
It is provided with Magnet.The enriching apparatus simple structure, it is easy to operate, an enrichment frame is constituted by shelving plate, gripper shoe and base plate,
Magnet is set in gripper shoe, on enrichment frame the enrichment test tube with immunomagnetic beadses is shelved, Biosample is poured into when using is equipped with
In the enrichment test tube of immunomagnetic beadses, the biology matched with the immunomagnetic beadses is adsorbed by immunomagnetic beadses, then will be equipped with biological examination
The enrichment test tube of sample is shelved on enrichment frame, will be adsorbed with the biological immunomagnetic beadses of detection by the Magnet in gripper shoe and is adsorbed onto
On test tube wall, whole enrichment box is then operated to pour out remaining Biosample, just can effectively be enriched to needs the life of detection
Thing sample；The cavity for being set as a front opening, the setting of the opening are enclosed additionally by base plate, top board, backboard and two side plates
It is easy to observe the enrichment condition of biological specimen；Top board both sides can be arranged on respectively the inner side end of two side plates pull
On, the position of top board is adjusted by draw operation, it is easy to be enriched with picking and placeing and operating for test tube.
Described gripper shoe is arranged on the centre position of described cavity and described base plate is divided into into noseplate and rear bottom
Plate, the both sides of described gripper shoe are connected respectively with the side plate described in two, and described shelves plate positioned at described noseplate
Top, described rear base plate, enclose between gripper shoe, backboard and two side plates and be set as described object placing cavity, described noseplate,
Shelve to be enclosed between plate, gripper shoe and two side plates and be set as an enrichment chamber.Gripper shoe is arranged on the centre position of cavity so that empty
Chamber is divided into object placing cavity and enrichment chamber two chambers, and object placing cavity can be used to put the article related to biological specimen collection, such as
Microscope slide, sampling reagent etc. so that the enriching apparatus are provided simultaneously with function of containing articles, vdiverse in function.
Described enrichment intracavity is vertically uniformly arranged at intervals with multiple dividing plates, is formed between the dividing plate described in adjacent two
One independent enrichment room, is correspondingly arranged on described in one on the enrichment room described in each and shelves through hole, the richness described in each
Collection interior is provided with one and shelves seat, and described seat of shelving is fixedly installed on described noseplate, and described being shelved arrange on seat
Cavity is shelved, described shelves cavity positioned at the described underface for shelving through hole.Chamber will be entirely enriched with by dividing plate to separate
Into multiple independent enrichment rooms, each enrichment room can carry out independent enrichment procedure, be easy to observe and distinguish.Shelve the setting of seat
So that enrichment test tube shelves more stable, the bottom for being enriched with test tube is shelved on and shelves in cavity, it is to avoid when enrichment box is subject to outer
The masterpiece used time is enriched with test tube double swerve, and so as to affecting concentration effect, and shelving cavity the underface for shelving through hole is located at, it is ensured that
It is enriched with shelving vertically to shelve for test tube, it is ensured that concentration effect.
Magnet is embedded in the inside for being arranged on gripper shoe, it is to avoid Magnet is chronically exposed in air occurs chemical reaction impact suction
Attached effect.
The upper interior end face of the side plate described in two is provided with the chute being engaged with described top plate thickness, described top
The both sides of plate are slidably disposed in described chute.By chute realize top board before and after pull, be convenient for enrichment and
The operation of article is picked and placeed, simple structure is easy to operate.
Described shelving is provided with vertical baffle plate on plate.The baffle plate is used to prevent the object of glove intracavity from dropping out.
The tread plate for raising up is provided with described top board.Tread plate is easy to operate the pull of top board with handss.
The arrow for indicating pull direction is provided with described top board.Arrow is used to indicate taking out for top board
Draw direction, it is to avoid maloperation.
Be provided with vertical installation chute on side plate described in two, it is described under shelve the rear end face of plate and be relatively set with
Two support arms, are provided with and the described installation slide block that chute is engaged of installing on the inner face of the support arm described in two,
Described chute of installing realizes the dismounting and installation of described enrichment box with the cooperation of installation slide block.By installing chute and installing
The dismounting and installation of enrichment box is realized in the cooperation of slide block, and simple structure is easy to operate.
Compared with prior art, it is an advantage of the current invention that：Enrichment box for biological sample collection is removably disposed
On support, and object placing cavity is provided with enrichment box, glove intracavity places the hybridizing reagent related to detection, hybridizing box and biology
Chip, each equipment of detection is combined, and neat and small volume is easy to movement, and simple structure is easy to use.
Description of the drawings
Fig. 1 is the overall structure diagram of bio-chip test device in the present invention；
Fig. 2 is the structural representation of medium-height trestle of the present invention；
Fig. 3 removes the structural representation of width adjusting bar and clamping plate for Fig. 2；
Fig. 4 is the cross section structure diagram that camber adjustable plate of the present invention is engaged with upper side shield；
Fig. 5 be in the present invention under shelve the cross section structure diagram of plate；
Fig. 6 is the configuration schematic diagram that bio-chip test device removes support and mobile phone in the present invention；
Fig. 7 is the cross section structure diagram that bio-chip test device removes support and mobile phone in the present invention；
Fig. 8 is the structural representation that test tube is enriched with the present invention；
Fig. 9 is the structural representation that box is enriched with the present invention；
Figure 10 is that the structural representation that box removes top board is enriched with the present invention；
Figure 11 is the present invention looks up structural representation of bio-chip test device in the present invention；
Figure 12 is that the structural representation that box is installed on support is enriched with the present invention.
Specific embodiment
The present invention is described in further detail below in conjunction with accompanying drawing embodiment.
Embodiment one：As shown in Figures 1 to 12, a kind of biological chips detection system, including bio-chip test device and
For the enriching apparatus of biological specimen collection, bio-chip test device includes support A, image capturing machine is provided with support A
Structure B, biochip loader mechanism C and light source mechanism D, image capturing mechanism B is arranged on before biochip loader mechanism C, light
Source mechanism D is arranged on after biochip loader mechanism C；Enriching apparatus include that enrichment box H, enrichment box H are removably disposed in
On support A, storage in object placing cavity H5, object placing cavity H5 is provided with enrichment box H and is provided with hybridizing reagent（Do not show in figure）, hybridization
Box（Do not show in figure）With biochip G.
In this particular embodiment, support A include being shelved on vertically arranged plate A1 and under shelve plate A2, above shelve plate A1
The top for shelving plate A2 can be adjustably arranged on down up and down, above shelve plate A1 front end face shelve with plate A2 front end face it is neat
Flat, the both sides for above shelving plate A1 are respectively arranged with the upper side shield A11 for extending forward, under shelve the both sides of plate A2 and respectively forwardly prolong
Stretch and be provided with lower side shield A21, upper side shield A11 and lower side shield A21 positions up and down with respect to and upper side shield A11 medial extremity
Face flushes with the inner side end of lower side shield A21, under shelve the bottom of plate A2 and be extended forward and have horizontal lower location-plate
A22, upper side shield A11, lower side shield A21, on shelve plate A1, under shelve to be enclosed between plate A2 and lower location-plate A22 and be set as one
Shelve chamber E.Above-mentioned supporting structure is simple, easily manufactured, above shelves plate A1 and can adjustably be arranged on down up and down and shelves on plate A2, makes
Obtaining support A can be adapted to the mobile phone B 1 of different length, and lower location-plate A22 plays a part of lower positioning to mobile phone B1, it is ensured that handss
Machine B1 can be stably seated on support A.
In this particular embodiment, the first vertical guide chute A111 is provided with upper side shield A11, first is oriented to cunning
Can slide up and down in groove A111 and be provided with the first lead column A112, below the first lead column A112 height regulating rod is connected with
The lower surface of A3, upper side shield A11 is provided with height adjusting holes A113, and the vertical centrage of height adjusting holes A113 is led with first
Coincide to the vertical centrage of chute A111, and height adjusting holes A113 is connected with the first guide chute A111, height is adjusted
Stretch out height adjusting holes A113 and be fixedly installed on lower side shield A21 in the bottom of pole A3.By the first guide chute A111
With the cooperation of the first lead column A112, the motion to height regulating rod A3 play the guiding role.
In this particular embodiment, the internal diameter of height adjusting holes A113 is more than the external diameter of height regulating rod A3 and less than first
The external diameter of lead column A112.External diameter of the internal diameter of height adjusting holes A113 more than height regulating rod A3 is less than the first lead column A112
External diameter, it is ensured that height regulating rod A3 can be swimmingly up and down and can be stably mounted to shelve on plate A1.
In this particular embodiment, the front end face of upper side shield A11 is provided with internal thread hole A114, internal thread hole A114 with
First guide chute A111 is connected, and lock-screw F is bolted with internal thread hole A114, by lock-screw F by altitude mixture control
The position of bar A3 is locked.The front end face of upper side shield A11 is provided with internal thread hole A114, is bolted with internal thread hole A114
Lock-screw F, after the completion of above shelving the altitude mixture control of plate A1, is consolidated the position of height regulating rod A3 by tightening lock-screw F
Live calmly.
In this particular embodiment, image capturing mechanism B includes the mobile phone B 1 with camera function and image capturing plate B2, handss
Machine B1 is shelved on and shelves in the E of chamber, above shelves the image capturing window A12 that before and after insertion is provided with plate A1, image capturing plate B2
Can slidingly be arranged on image capturing window A12, the front end face of image capturing plate B2 shelves the front end face of plate A2 with
Flush, the image capturing hole B21 of before and after insertion is provided with image capturing plate B2, biochip loader mechanism C is located in image
The rear of capture hole B21.Above-mentioned image capturing mechanism B structure is simple, easy to operate, and upper insertion before and after setting on plate A1 is shelved
Image capturing window A12, can slidingly arrange on image capturing window A12 one with image capturing hole B21 figure
As capture board B2, the mobile phone B 1 that photographic head is arranged on diverse location is adapted to by the position of left and right adjusting image capturing plate B2, tool
When body is used, mobile phone B 1 is put to be shelved on and is shelved in the E of chamber, adjust image capturing plate B2 right position and on shelve plate A1's
Upper-lower position, enables the photographic head in mobile phone B 1 to be directed at image capturing hole B21, and the bottom of mobile phone B 1 can stably be shelved on
On lower location-plate A22, then the biological core loaded on biochip loader mechanism C is captured by the mobile phone B 1 with camera function
Bio information on piece G.
In this particular embodiment, two inner faces up and down of image capturing window A12 are provided with and image capturing plate B2
The chute A121 that thickness is engaged, image capturing plate B2 is slidably disposed on the upper surface that plate A1 is above shelved in chute A121
It is provided with vertical locking hole (not shown), the chute A121 on locking hole and image capturing window A12 upper interior ends face
It is connected, a lock-screw F is bolted with locking hole, is fixed the position of image capturing plate B2 by lock-screw F.Pass through
The chute A121 being engaged with image capturing plate B2 thickness realizes horizontally slipping for image capturing plate B2, can be adapted to different photographic head
The mobile phone B 1 of position, simple structure is easy to operate.
In this particular embodiment, the clamp system being provided with plate A2 for mobile phone to be fixedly clamped is shelved under, is clamped
Mechanism includes width adjusting bar A23 and clamping plate A24, and the front end face for above shelving plate A2 is provided with the groove A25 being recessed backward, under
Shelve and the second horizontal guide chute A26 is provided with plate A2, second can be slidingly provided with the second guide chute A26
Lead column A27, is provided with horizontal back-moving spring A28 between the second lead column A27 and the second guide chute A26 side end faces, recessed
Width adjusting hole A251, the cross central line and the second guide chute of width adjusting hole A251 are provided with the side end face of groove A25
The cross central line of A26 overlaps, and width adjusting hole A251 is connected with the second guide chute A26, one end of width adjusting bar A23
Stretch into width adjusting hole A251 to be connected with the second lead column A27, clamping plate A24 is fixedly installed on the another of width adjusting bar A23
One end.Above-mentioned clamp system causes mobile phone B 1 to be shelved on when shelving in the E of chamber, and right position also can be accurately positioned, and be passed through
Guide effect is played in the motion of second guide chute A26 and the second lead column A27 to width adjusting bar A23, and back-moving spring A28 gives
Mono- tightening force of clamping plate A24, simple structure is easy to operate, and clamps stable.
In this particular embodiment, external diameter of the internal diameter of width adjusting hole A251 more than width adjusting bar A23 and less than the
The external diameter of two lead columns A27.The internal diameter of width adjusting hole A251 is more than the external diameter of width adjusting bar A23 and less than the second lead column
The external diameter of A27 so that width adjusting bar A251 can swimmingly horizontally slip and with a stable positioning.
In this particular embodiment, pull out with clamping plate A24 and be provided with and folder on the consistent lower side shield A21 in direction
The opening A212 that tight plate A24 is engaged, the inner side end for pulling out lower side shield A21 in opposite direction with clamping plate A24 sets
It is equipped with neonychium A211.Arrange on the consistent lower side shield A21 in direction opening A212 pulling out with clamping plate A24, this is opened
Mouth A212 facilitates the operation of clamp system, and the inner of lower side shield A21 in opposite direction is being pulled out with clamping plate A24
Face arranges neonychium A211, and neonychium A211 then shields to the sidepiece of mobile phone B1.
In this particular embodiment, biochip loader mechanism C includes load frame C1 and load frame mounting seat C2, dress
The rectangular watch window C11 that before and after insertion is provided with framework C1 is carried, is vertically provided with load frame C1 and biological core
The first slot C12 that piece G is engaged, biochip G insert the detection examination being arranged in the first slot C12 and on biochip G
Sample is located in watch window C11；The cylindric inner chamber C21 of before and after insertion, load frame are provided with load frame mounting seat C2
The second slot C22 being engaged with load frame C1 of up/down perforation is provided with mounting seat C2, the insertion of load frame C1 is arranged
In the second slot C22；Load frame mounting seat C2 be arranged on image capturing plate B2 rear end face on, cylindric inner chamber C21 with
Image capturing hole B21 is coaxial, and between image capturing hole B21 and cylindric inner chamber C21 lens C3 is provided with.Load frame C1 structure
Simply, the first slot C12 is used to make biochip G insert in it, and to biochip G a stable installation positioning is provided, and sees
Examine window C11 and be easy to observation；The the second slot C22 arranged in load frame mounting seat C2 is used to insert load frame C1, cylinder
Shape inner chamber C21 is coaxial with image capturing hole B21, it is ensured that by image capturing hole B21 can accurate observation on biochip G
Bio information, arranges lens C3, by lens C3 by biochip G between image capturing hole B21 and cylindric inner chamber C21
Bio information amplify, be easy to mobile phone B 1 to capture more clearly biometric image.
In this particular embodiment, the front end face of load frame mounting seat C2 is provided with for the cylindrical shape of mounted lens C3
Installation cavity C23, cavity C23 is installed coaxial with cylindric inner chamber C21 and the internal diameter of cavity C23 is installed is more than cylindrical shape inner chamber
The internal diameter of C21, the size of lens C3 is closed with the matching size for installing cavity C23.The installation arranged in load frame mounting seat C2
Cavity C23 is used to provide a stable installation positioning to lens C3, installs cavity C23 coaxial with cylindric inner chamber C21 so that
Lens C3 can preferably play the effect for amplifying the bio information on biochip G, and the internal diameter for installing cavity C23 is more than cylinder
The internal diameter of shape inner chamber C21, the size of lens C3 is closed with the matching size for installing cavity C23 so that lens C3 can be installed stably
Installing in cavity C23, it is to avoid lens C3 to fall to affected in cylindric inner chamber C21 and normally uses.
In this particular embodiment, it is provided with load frame mounting seat C2 for adjusting load frame C1 upper-lower position
Position adjusting mechanism.Upper-lower position of load frame C1 in load frame mounting seat C2 is adjusted by position adjusting mechanism, from
And enable the bio information on biochip G to obtain complete capture.
In this particular embodiment, position adjusting mechanism includes the regulation internal gear 1 for cooperating and regulation external gear 2,
Load frame mounting seat C2 includes columned front pedestal 3 and the rear pedestal 4 being coaxially disposed, and the external diameter of front pedestal 3 is more than rear base
The external diameter of seat 4, the second slot C22 is arranged on front pedestal 3, the sidepiece of load frame mounting seat C2 be uniformly distributed along the circumference be provided with to
Few two depressed part C24, depressed part C24 are connected with cylindrical shape inner chamber C21, adjust external gear 2 and are rotatably arranged in depression
In portion C24, two lateral surface of load frame C1 are provided with and adjust the tooth bar C13 that external gear 2 is engaged, and adjust internal gear 1
It is set on rear pedestal 4 and is meshed with external gear 2 is adjusted, the insertion of load frame C1 is arranged in the second slot C22 and tooth bar
C13 is meshed with external gear 2 is adjusted, and the rear portion of rear pedestal 4 is coaxially disposed restraining position ring block 5.Above-mentioned position adjusting mechanism, structure letter
Single, easy to operate, rear pedestal 4 is used to install regulation external gear 1, by front pedestal 3 and spacing ring 5 to the peace for adjusting internal gear 1
Dress provides a front limit and rear spacing, it is ensured that adjust the stable installation of internal gear 1, rotates during regulation and adjusts internal gear 1, drives
The regulation external gear 2 being meshed therewith is rotated, and drives the tooth bar C13 being meshed with the regulation external gear 2 to move up and down, so that
Obtain load frame C1 to move up and down along the second slot C22, the upper-lower position for realizing load frame C1 is adjusted.
In this particular embodiment, the sidepiece of rear pedestal 4 is provided with the 3rd slot 41 of insertion, and the 3rd slot 41 is inserted into
It is provided with scattering sheet 6.Scattering sheet 6 is inserted in the 3rd slot 41, the equalizing light rays that light source mechanism D can be emitted,
It is easy to that biochip G is clearly viewed.
In this particular embodiment, external diameter of the external diameter of spacing ring 5 more than rear pedestal 4.The external diameter of spacing ring 5 is more than rear base
The external diameter of seat 4, it is ensured that spacing ring 5 plays stable rear position-limiting action.
In this particular embodiment, anti-slop serrations 11 have been uniformly arranged on the lateral wall for adjusting internal gear 1.Anti-slop serrations 11 set
Putting can increase the frictional force for adjusting the lateral wall of internal gear 1, be easy to carry out rotating operation to it.
In this particular embodiment, light source mechanism D includes light source D1, driving power supply D2, light source mounting seat D3 and drives electricity
Source mounting seat D4, light source mounting seat D3 is fixedly mounted on the rear end of spacing ring 5, and before and after insertion is provided with light source mounting seat D3
And the printing opacity chamber D31 coaxial with cylindric inner chamber C21, light source D1 are arranged in the D31 of printing opacity chamber, the rear end of light source D1 be provided with
The power supply conduction panel D11 of light source D1 electrical connections, driving power supply D2 is arranged in driving power supply mounting seat D4, driving power supply mounting seat
D4 is arranged on the rear of light source mounting seat D3, and trigger board D21 is provided with driving power supply D2, and trigger board D21 is just turned on to power supply
Plate D11, the power supply conducting when trigger board D21 is contacted with power supply conduction panel D11 makes light source D1 light.Above-mentioned light source mechanism D structure
Simply, by light source mounting seat D3 and driving power supply mounting seat D4 respectively to light source D1 and driving power supply D2 provide one it is stable
Installing space, by the separation between power supply conduction panel D11 and trigger board D21 and contact closing and the opening of light source D1 are realized,
It is simple to operate, it is easy to use.
In this particular embodiment, the rear end of light source mounting seat D3 is provided with externally threaded mounting ring D32, and shape is not used
Under state, in mounting ring D32, trigger board D21 is separated driving power supply mounting seat D4 screwing sections with power supply conduction panel D11, makes
Used time, screwing driving power supply mounting seat D4 makes trigger board D21 contact with power supply conduction panel D11, and light source D1 lights.Said structure
Driving power supply mounting seat D4 can not only be stably mounted in light source mounting seat D3, while power supply conduction panel can be realized quickly
Separate between D11 and trigger board D21 and contact, simple structure is easy to operate.
In this particular embodiment, the lateral part of driving power supply mounting seat D4 has been uniformly arranged anti-slop serrations D41.Anti-slop serrations
The setting of D41 can increase the frictional force of driving power supply mounting seat D4 lateral wall, be easy to carry out rotating operation to it.
In this particular embodiment, lower side shield A21 extends back and is provided with adjutage A29.Adjutage A29 is to whole
Frame A plays a supporting role.
During specifically used above-mentioned bio-chip test device, mobile phone B 1 is shelved on into the shelving in the E of chamber, in regulation of support A
The position of plate A1 and image capturing plate B2 is shelved, makes the photographic head in mobile phone B 1 be directed at image capturing hole B21, will be with detection examination
The biochip G of sample is inserted in load frame C1, detection sample is located in watch window C11, and load frame C1 is inserted
In entering the second slot C22 in load frame mounting seat C2, rotate driving power supply mounting seat D4, make power supply conduction panel D11 with
Trigger board D21 contacts, and circuit of light sources conducting, light source D1 lights, and opens the camera function of mobile phone B 1, now just it can be seen that logical
The bio information of the detection sample crossed on the biochip G of lens C3 amplifications, by position adjusting mechanism load frame C1 is adjusted
Upper-lower position, such mobile phone B 1 just can capture the bio information of the detection sample on diverse location, by mobile phone B 1 pair not
Taken pictures with the bio information of the detection sample on position, just can be obtained clearly biometric image information.
In this particular embodiment, enriching apparatus also include enrichment test tube K, enrichment box H include base plate H11, top board H12,
Backboard H13 and two side plate H14, base plate H11 are horizontally disposed, and two side plate H14 are vertically provided at respectively the both sides of base plate H11,
Backboard H13 is vertically provided on base plate H11 and the both sides of backboard H13 are connected respectively with two side plate H14, and the two of top board H12
Side can be arranged on respectively on the inner side end of two side plate H14 pull, base plate H11, top board H12, backboard H13 and two side plates
The cavity for being set as a front opening is enclosed between H14, one is horizontally arranged with cavity and is shelved plate H3, shelve the both sides difference of plate H3
It is connected with two side plate H14, shelves and be connected by vertically arranged gripper shoe H4 between plate H3 and base plate H11, shelves
Be provided with plate H3 it is multiple shelve through hole H31 with enrichment test tube K is engaged, enrichment test tube K is shelved on and shelves in through hole H31,
Immunomagnetic beadses K21 is provided with enrichment test tube K, Magnet is provided with gripper shoe H3（Do not show in figure）.The enriching apparatus structure
Simply, it is easy to operate, an enrichment frame is constituted by shelving plate H3, gripper shoe H4 and base plate H11, magnetic is set in gripper shoe H4
Ferrum, on enrichment frame the enrichment test tube K with immunomagnetic beadses K21 is shelved, and pours Biosample equipped with immunomagnetic beadses K21 into when using
Enrichment test tube K in, the biology matched with immunomagnetic beadses K21 is adsorbed by immunomagnetic beadses K21, then will be equipped with Biosample
Enrichment test tube K be shelved on enrichment frame, the biological immunomagnetic beadses K21 of detection will be adsorbed with by the Magnet in gripper shoe H4 and inhaled
It is attached on test tube wall, then operates whole enrichment box H to pour out remaining Biosample, just can effectively be enriched to needs detection
Biological specimen；The sky for being set as a front opening is enclosed additionally by base plate H11, top board H12, backboard H13 and two side plate H14
Chamber, the setting of the opening is easy to observe the enrichment condition of biological specimen；Top board H12 both sides can be arranged on respectively pull
On the inner side end of two side plate H14, the position of top board is adjusted by draw operation, be easy to be enriched with picking and placeing and operating for test tube K.
In this particular embodiment, gripper shoe H4 be arranged on the centre position of cavity by base plate H11 be divided into noseplate and
Base plate afterwards, the both sides of gripper shoe H4 are connected respectively with two side plate H14, shelve plate H3 positioned at the top of noseplate, rear base plate,
Enclose between gripper shoe H4, backboard H13 and two side plate H14 and be set as object placing cavity H5, noseplate, shelve plate H3, gripper shoe H4 and two
Enclose between individual side plate H14 and be set as an enrichment chamber.Gripper shoe H4 is arranged on the centre position of cavity so that cavity is divided into be put
Thing chamber H5 and enrichment chamber two chambers, object placing cavity H5 can be used to putting the article related to biological specimen collection, such as microscope slide, adopt
Sample reagent etc. so that the enriching apparatus are provided simultaneously with function of containing articles, vdiverse in function.
In this particular embodiment, it is enriched with intracavity and is vertically uniformly arranged at intervals with multiple dividing plate H7, two adjacent dividing plates
An independent enrichment room H61 is formed between H7, one is correspondingly arranged on each enrichment room H61 and is shelved through hole H31.By every
Whole enrichment chamber is separated into multiple independent enrichment room H61 by plate H7, and each enrichment room H61 can carry out independent enrichment procedure,
It is easy to observe and distinguishes.
In this particular embodiment, it is provided with one and shelves a H8 in each enrichment room H61, shelves before a H8 is fixedly installed on
On base plate, shelve to be provided with a H8 and shelve cavity H81, shelve cavity H81 and be located at the underface for shelving through hole H31.Shelve seat
The setting of H8 causes enrichment test tube K's to shelve more stable, and the bottom of enrichment test tube K is shelved on shelves in cavity H81, it is to avoid when
Enrichment box H is enriched with test tube K double swerves when being acted on by external force, shelves so as to affect concentration effect, and shelve cavity H81 to be located at
The underface of through hole H31, it is ensured that enrichment test tube K's shelves vertically to shelve, it is ensured that concentration effect.
In this particular embodiment, Magnet is embedded is arranged in gripper shoe H4.Magnet is embedded in and is arranged on the interior of gripper shoe H4
Portion, it is to avoid Magnet is chronically exposed in air occurs chemical reaction impact adsorption effect.
In this particular embodiment, the upper interior end face of two side plate H14 is provided with the cunning being engaged with top board H12 thickness
The both sides of groove H141, top board H12 are slidably disposed in chute H141.Taking out in front and back for top board H12 is realized by chute H141
Draw, be convenient for being enriched with and picking and placeing the operation of article, simple structure is easy to operate.
In this particular embodiment, shelve and vertical baffle plate H32 is provided with plate H3.Baffle plate H32 is used to prevent glove
Object in the H5 of chamber is dropped out.
In this particular embodiment, the tread plate H121 for raising up is provided with top board H12.Tread plate H121 is easy to use
Handss operate the pull of top board H12.
In this particular embodiment, the arrow H122 for indicating pull direction is provided with top board H12.Indicator
Head H122 is used to indicate the pull direction of top board H12, it is to avoid maloperation.
During the above-mentioned enrichment test tube of concrete operations, the immunity matched with biological specimen to be extracted is put in enrichment test tube K
Magnetic bead K21, then pours Biosample in enrichment test tube K into, and the biology matched with immunomagnetic beadses K21 is by immunomagnetic beadses
K21 adsorbs, and the enrichment test tube K that then will be equipped with Biosample is shelved on enrichment frame, will be inhaled by the Magnet in gripper shoe H4
It is adsorbed onto on test tube wall with the biological immunomagnetic beadses K21 of detection, then inclines enrichment box H, makes liquid in enrichment test tube K fall
Go out, just can effectively be enriched to needs the biological specimen of detection.
In this particular embodiment, vertical installation chute H142 is provided with two side plate H14, under shelve after plate A2
End face is relatively set with two support arm A20, is provided with the inner face of two support arm A20 and is engaged with installation chute H142
Installation slide block A201, install chute A201 with install slide block H142 cooperation realize enrichment box H dismounting and installation.
Above-mentioned biological chips detection system using mobile phone obtain biometric image, therefore whole device can manufacture ground volume compared with
It is little, it is suitable to be used in palm, it is easy to operate.
Embodiment two：Other parts are identical with embodiment one, and its difference is to be provided with adjutage A29 for propping up
The support feet 9 of support support A.Support feet 9 is provided with adjutage A29 and further functions as supporting role to whole support A, made
Obtain whole support A and be stabilized support.
In this particular embodiment, the support angle of support feet 9 is adjustable and can move up and down along adjutage A29.9 jiaos of support feet
Degree is adjustable and can move up and down along adjutage A29 so that the support angle of support A is adjustable, is easy to the handss to being shelved on support A
Machine B1 is operated.
Claims (10)
1. a kind of biological chips detection system, including bio-chip test device and the enriching apparatus for biological specimen collection,
It is characterized in that described bio-chip test device includes support, image capturing mechanism, biology are provided with described support
Chip loader mechanism and light source mechanism, described image capturing mechanism is arranged on before described biochip loader mechanism, institute
The light source mechanism stated is arranged on after described biochip loader mechanism；Described enriching apparatus include enrichment box, described
Enrichment box is removably disposed on described support, and object placing cavity is provided with described enrichment box, and described glove intracavity is received
Receive and be provided with hybridizing reagent, hybridizing box and biochip.
2. a kind of biological chips detection system as claimed in claim 1, it is characterised in that described support includes vertically arranged
On shelve plate and under shelve plate, it is described on shelve plate can adjustably be arranged on up and down it is described under shelve the top of plate, institute
Shelve on stating the front end face of plate with it is described under shelve the front end face of plate and flush, it is described on shelve the both sides of plate and be respectively provided with
Have a upper side shield for extending forward, it is described under shelve the both sides of plate and be respectively forwardly extended and have lower side shield, described is upper
Side shield and described downside baffle position up and down with respect to and described upper side shield inner side end and described lower side shield
Inner side end flush, it is described under shelve the bottom of plate and be extended forward and have horizontal lower location-plate, described upper side block
Plate, lower side shield, on shelve plate, under shelve to be enclosed between plate and described lower location-plate and be set as one and shelve chamber.
3. a kind of biological chips detection system as claimed in claim 2, it is characterised in that described image capturing mechanism includes
Mobile phone with camera function and image capturing plate, described mobile phone is shelved on described intracavity of shelving, it is described on shelve on plate
The image capturing window of before and after insertion is provided with, described image capturing plate can slidingly be arranged on described image capturing
On window, the front end face of described image capturing plate with it is described under shelve the front end face of plate and flush, described image capturing plate
On be provided with the image capturing hole of before and after insertion, described biochip loader mechanism is located at behind described image capturing hole
Side.
4. a kind of biological chips detection system as claimed in claim 3, it is characterised in that described biochip loader mechanism
Including load frame and load frame mounting seat, the rectangular observation window of before and after insertion is provided with described load frame
Mouthful, the first slot being engaged with biochip is vertically provided with described load frame, described biochip insertion sets
Put the detection sample in the first described slot and on described biochip to be located in described watch window；Described dress
The cylindric inner chamber that before and after insertion is provided with framework mounting seat is carried, in described load frame mounting seat up/down perforation is provided with
The second slot being engaged with described load frame, described load frame insertion is arranged in the second described slot；
Described load frame mounting seat is arranged on the rear end face of described image capturing plate, described cylindric inner chamber with it is described
Image capturing hole is coaxial, and between described image capturing hole and described cylindric inner chamber lens are provided with.
5. a kind of biological chips detection system as claimed in claim 4, it is characterised in that in described load frame mounting seat
The position adjusting mechanism for adjusting load frame upper-lower position is provided with, described position adjusting mechanism includes what is cooperated
Adjust internal gear and adjust external gear, described load frame mounting seat includes the columned front pedestal being coaxially disposed and rear base
Seat, the external diameter of described front pedestal is more than the external diameter of described rear pedestal, and the second described slot is arranged on described front pedestal
On, the sidepiece of described load frame mounting seat is symmetrically arranged with two depressed parts, described depressed part and described cylindrical shape
Intracavity inter-connection, the described external gear that adjusts is rotatably arranged in described depressed part, two of described load frame
Lateral surface is provided with and the described tooth bar that external gear is engaged that adjusts, and the described inner gear housing that adjusts is located at described rear pedestal
It is meshed above and with described regulation external gear, described load frame insertion is arranged in the second described slot and described
Tooth bar is meshed with described regulation external gear, and the rear portion of described rear pedestal is coaxially disposed restraining position ring block.
6. a kind of biological chips detection system as claimed in claim 5, it is characterised in that described light source mechanism include light source,
Driving power supply, light source mounting seat and driving power supply mounting seat, described light source mounting seat is fixedly mounted on described spacing ring
Rear end, be provided with described light source mounting seat before and after insertion and with the printing opacity chamber of described cylindric coaxial, it is described
Light source be arranged on described printing opacity intracavity, the rear end of described light source is provided with the power supply that electrically connect with described light source and turns on
Plate, described driving power supply is arranged in described driving power supply mounting seat, and described driving power supply mounting seat is arranged on described
Light source mounting seat rear, trigger board is provided with described driving power supply, described trigger board is just led to described power supply
Logical plate, the power supply conducting when described trigger board is with described power supply conducting contact makes described light source luminescent.
7. a kind of biological chips detection system as claimed in claim 2, it is characterised in that described enriching apparatus also include richness
Collection test tube, described enrichment box includes base plate, top board, backboard and two side plates, and described floor level is arranged, described in two
Side plate is vertically provided at respectively the both sides of described base plate, and described backboard is vertically provided on described base plate and the described back of the body
The both sides of plate are connected respectively with the side plate described in two, and the both sides of described top board can be arranged on respectively described in two pull
Side plate inner side end on, described base plate, between top board, backboard and two side plates enclose the sky for being set as a front opening
Chamber, is horizontally arranged with one and shelves plate in described cavity, the described both sides for shelving plate are connected respectively with the side plate described in two
Connect, described being shelved be connected by a vertically arranged gripper shoe between plate and described base plate, and described being shelved set on plate
Be equipped with it is multiple be engaged with described enrichment test tube shelve through hole, described enrichment test tube is shelved on described shelves through hole
It is interior, immunomagnetic beadses are provided with described enrichment test tube, it is provided with Magnet in described gripper shoe.
8. a kind of biological chips detection system as claimed in claim 7, it is characterised in that described gripper shoe is arranged on described
The centre position of cavity described base plate is divided into into noseplate and rear base plate, the both sides of described gripper shoe respectively with two
Described side plate is connected, and described shelves plate positioned at the top of described noseplate, described rear base plate, gripper shoe, backboard
Enclose and two side plates between and be set as described object placing cavity, described noseplate, shelve to be enclosed between plate, gripper shoe and two side plates and set
Into an enrichment chamber.
9. a kind of biological chips detection system as claimed in claim 8, it is characterised in that described enrichment intracavity is vertically uniform
Multiple dividing plates are arranged at intervals with, an independent enrichment room, the richness described in each are formed between the dividing plate described in adjacent two
It is correspondingly arranged on described in one on collection room and shelves through hole, the enrichment interior described in each is provided with one and shelves seat, and described puts
Put seat to be fixedly installed on described noseplate, described being shelved be provided with seat and shelve cavity, and described cavity of shelving is located at
The described underface for shelving through hole.
10. a kind of biological chips detection system as claimed in claim 7, it is characterised in that be provided with the side plate described in two
Vertical installation chute, it is described under shelve the rear end face of plate and be relatively set with two support arms, the support arm described in two
Be provided with inner face and it is described the installation slide block that chute is engaged is installed, it is described chute to be installed and the cooperation of slide block is installed
Realize the dismounting and installation of described enrichment box.
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| CN109613289A (en) * | 2018-12-27 | 2019-04-12 | 宁波大学 | A kind of qualitative/quantitative biological chips detection system |
| CN111190021A (en) * | 2020-02-22 | 2020-05-22 | 王国富 | Biological sample processing box |
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| WO2016205736A1 (en) * | 2015-06-19 | 2016-12-22 | The Regents Of The University Of California | Micro-plate reader for elisa testing |
| CN105181700A (en) * | 2015-09-29 | 2015-12-23 | 宁波大学 | Biochip detector |
| CN105181699A (en) * | 2015-09-29 | 2015-12-23 | 宁波大学 | Onboard seaborne/vehicle-mounted terrestrial biota chip detection system |
| CN205761217U (en) * | 2016-04-28 | 2016-12-07 | 宁波大学 | A kind of biochip hybridizing device |
| CN206420879U (en) * | 2016-12-28 | 2017-08-18 | 宁波大学 | A kind of biological chips detection system |
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| WO2019048427A1 (en) * | 2017-09-06 | 2019-03-14 | Gottfried Wilhelm Leibniz Universität Hannover | Holder structure, optical sensor module and set formed thereby |
| CN109613289A (en) * | 2018-12-27 | 2019-04-12 | 宁波大学 | A kind of qualitative/quantitative biological chips detection system |
| CN111190021A (en) * | 2020-02-22 | 2020-05-22 | 王国富 | Biological sample processing box |
| CN111190021B (en) * | 2020-02-22 | 2023-08-11 | 武汉泰沃科技有限责任公司 | Biological sample processing box |
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