CN102445414B - Test device used for medical examination - Google Patents
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- CN102445414B CN102445414B CN 201110281722 CN201110281722A CN102445414B CN 102445414 B CN102445414 B CN 102445414B CN 201110281722 CN201110281722 CN 201110281722 CN 201110281722 A CN201110281722 A CN 201110281722A CN 102445414 B CN102445414 B CN 102445414B
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Abstract
The invention provides a test device used for medical examination, comprising a base (101), a movable microscope carrier (102) which is designed on the base (101) and is used for conveying test components and a movable light source transmitting and receiving device (103) which is arranged above the microscope carrier (102). Moving paths of the microscope carrier (102) and the light source transmitting and receiving device (103) or extending lines of the moving paths of the microscope carrier (102) and the light source transmitting and receiving device (103) are mutually intersected in the same plane or orthographic projections of the moving paths or the extending lines of the moving paths are mutually intersected in the same plane. The test device provided by the invention can stably and accurately convey the microscope carrier to a correct light source test position, the microscope carrier can move in the test device smoothly, noise interference is reduced, and detection result is accurate.
Description
Technical field
The present invention relates to a kind of proving installation of medically use, relate in particular to the proving installation of specimen Biochemical Indexes.
Background technology
Along with the progress of science and technology, the bedside in-vitro diagnosis experiment (POCT:Point of Care Testing) in the laboratory medicine field is arisen at the historic moment and is rapidly developed.20th century, " soak and read " dry chemical method (dip-and-read) of occurring of the fifties referred to the liquid detecting sample directly is added on business-like dry type reagent strip into the specific production of disparity items, moisture with tested sample causes specific chemical reaction as solvent, thereby carries out chemico-analytic method.Biochemical dry type test paper method receives people's concern with characteristics such as its finding speed easy to carry, simple to operate are fast, also plays a significant role in fast detecting at the scene.Introduction along with immune response and molecular biotechnology, the check field of medical science dry type test paper method expands to the detection to blood sugar, gestation, blood coagulable status, myocardial damage, acid base equilibrium, infectious diseases etc., and medicine concentration monitor (TMD), alcohol content detection, thrombotest, the analysis of Blood Biochemical Indexes, infectious disease sieve, hormonal readiness and microchip DNA diagnosis and drug abuse detection etc. during operation.Rely on the testing result of ocular estimate judgement dry chemical scrip, can only be as qualitative judgement, artificial subjective factor is very large on the judgement impact of testing result, is easy to cause erroneous judgement.Therefore for to make the interpretation of quick detection test paper more accurate, supporting miniaturization experimental apparatus progressively grows up with it.These easy and simple to handleization of detecting instrument, report the test are in time changed, accuracy, more and more are subject to clinical medical and nursing personnel, patient and family members' thereof favor.And the resulting data of these detecting instruments can also realize that remote wireless transmission is to laboratory computer management system or electronic health record.
US Patent No. 4780283 has disclosed a kind of dry chemical test paper analyser.This analyser comprises fixed detection light source, loads the hemispherical workbench of test paper bar.By the interaction between spring, hemispherical workbench being transported to the detection light source place detects.Due to the mechanicals efforts of just having utilized between spring, not only require to have very accurately control procedure on producing, increase production cost, and utilized the very difficult tram of controlling between reaction reagent bar and detection light source of interaction of spring, affected testing result.And hemispherical structure has increased the volume of whole analytical instrument.On the other hand, spring is short serviceable life, needs regular replacing spring, and this can make troubles to the user of instrument.
U.S. Praxsys Biosystems Inc. company has developed a kind of tachysynthesis detection system that can be used for quantitative and qualitative analysis judgement, disclose in US Patent No. 6136610, this system by detector and with it supporting Test paper box form.This system uses single channel, namely once only can detect single clinical samples.Because this detecting instrument once can only detect an index, so detection efficiency is lower.
Chinese patent application 200910160639.5 discloses a kind of multi-channel portable colloidal gold test paper device for quick testing, mainly comprises: 4 independently sense channel, ARM data processor, keyboard and LCD parts.The pick-up unit of this invention can be completed multiple test item fast and high-throughout.But 4 of this Chinese patent application independently sense channel and whole detector be an integral body, the instrument user can not arbitrarily change test event by changing sense channel.
Chinese patent application 200410052202.7 discloses a kind of quick diagnosis lateral flow assays system and method, this detection system comprises 1 master unit and 1 to 20 test module, and being connected to host computer by USB or blue teeth wireless receiver, host computer moves by the software control detector.This patented claim also discloses and has been designed to relatively independent relation between master unit and test module, and when master unit broke down, all proving installations can be removed and ressemble with another master unit.It is a very complicated process that the described test module of this patented claim disassembles from master unit, needs a lot of parts of breakdown.On the other hand, described test module is not the structure of a sealing, when the sample when retention in the test module that is removed has test or test agent, the sample that these are residual or reagent can be exposed in environment, environment around not only having polluted also can consist of operating personnel's life security dangerous.
Summary of the invention
In order to overcome above-mentioned shortcoming of the prior art, one of purpose of the present invention is to provide the proving installation that a kind of medical test is used.
1, the proving installation used of a kind of medical test; it is characterized in that: comprise that base 101, design transported the movably microscope carrier 102 of testing element and to be positioned at movably light source transmitter-receiver device 103 above microscope carrier 102 in being used on base 101; microscope carrier 102 can move back and forth at predefined track; light source transmitter-receiver device 103 can near and away from microscope carrier 102, the motion track of microscope carrier 102 and light source transmitter-receiver device 103 or the extended line of motion track mutually intersect in same plane or the orthogonal projection in same plane intersects mutually.
2, according to 1 described proving installation, it is characterized in that: when certain fixed area on microscope carrier 102 is positioned at orthogonal projection place of light source transmitter-receiver device 103 just, microscope carrier 102 stops mobile, then light source transmitter-receiver device 103 is near that fixed area on microscope carrier 102, detect, detect complete after again away from that fixed area on microscope carrier 102.
3, according to 2 described proving installations, it is characterized in that: proving installation also comprises the support of at least one fixing design on base 101, and described light source transmitter-receiver device 103 designs are on described support.
[0011]4, according to 3 described proving installations, it is characterized in that: described proving installation comprises at least two motors, drives respectively described microscope carrier 102 and light source transmitter-receiver device 103.
5, according to 4 described proving installations, it is characterized in that: described electro-motor is stepper motor 107,130.
6, according to 5 described proving installations, it is characterized in that: be fixed with rack-plate 111 on microscope carrier 102, stepper motor 107 with gear 108 is arranged on described support, and the gear 108 on stepper motor is connected with a joggle with the rack-plate 111 on microscope carrier 102, drives microscope carrier 102 and moves.
7, according to 3 described proving installations, it is characterized in that: be designed with left socle 104, right support 105 on base 101, be designed with upper bracket 106 on described left socle and right support, 103 designs of light source transmitter-receiver device are on upper bracket 106.
8, according to 1 described proving installation, it is characterized in that: light source transmitter-receiver device 103 comprises the optical coupled switch 132 that light source emitter 131, optical pickup apparatus and control light source transmitter-receiver device move.
9, according to 8 described proving installations, it is characterized in that: described smooth lotus root switch 132 has lightening hole 133, have shutter 134 on the light source transmitter-receiver device, described shutter 134 has the lightening hole of blocking 133 with respect to lightening hole 133 and leaves lightening hole 133 two positions.
10, according to 9 described proving installations, it is characterized in that: in the downward operational process of light source transmitter-receiver device 103, be positioned at lightening hole 133 tops of light lotus root switch 132 when shutter 134, this moment, light path was unimpeded, power supply keeps power supply state always, make light source emitter 131 continue to move downward under electro-motor 130 rotates, when shutter 134 has stopped the lightening hole 133 of light lotus root switch 132, light path is cut off, thereby close the power supply of the electro-motor 130 of light source transmitter-receiver device 103, and open light source transmitter-receiver device 103 and carry out the analysis of sample.
11, according to any one described proving installation of 1-10, it is characterized in that: base 101 fixedly is designed with track base 112, and microscope carrier 104 fixedly is designed with guide rail 113, and described guide rail 113 slides with track base 112 and makes up.
Two of purpose of the present invention is to provide a kind of medical detecting analyzer.
12, a kind of medical detecting analyzer, it is characterized in that: comprise a master control set 10 and at least one proving installation 100, wherein, master control set 10 comprises supply unit 11, control device, testing result output unit and the storage chamber 15 that is no less than the proving installation number, proving installation 100 comprises the microscope carrier 102 and the light source transmitter-receiver device 103 that is positioned at microscope carrier 102 tops for carrying detecting element and detection sample, proving installation 100 be placed in the storage chamber 15 of master control set and with the supply unit 11 of master control set, control device and testing result output unit are electrically connected to, the microscope carrier 102 that control device is controlled proving installation moves back and forth in certain direction, light source transmitter-receiver device 103 do on the direction substantially vertical with microscope carrier 102 moving directions near and away from the movement of microscope carrier, and detect the change color parameter that is placed in the detecting element on microscope carrier 102, then this parameter is delivered to control device, after processing through control device, via testing result output unit output detections result.
13, according to 12 described medical detecting analyzers, it is characterized in that: proving installation 100 can repeated multiple times extraction and group enter master control device 10.
14, according to 13 described medical detecting analyzers, it is characterized in that: be designed with rail structure between the inwall of the storage chamber 15 of the outer wall of proving installation 100 and master control set 10.
15, according to 14 described medical detecting analyzers, it is characterized in that: rail structure comprises guide rail 16 and the slide block structure 120 that is placed on storage chamber 15 inwalls and proving installation outer wall, and described slide block structure 120 can be in the interior slip of guide rail 16 of storage chamber 15.
16, according to any one described medical detecting analyzer of 12-15, it is characterized in that: the proving installation 100 that comprises two or more, each proving installation can detect the identical or different parameter that detects sample with kind, also can detect the identical or different parameter that variety classes detects sample.
17, according to 15 described medical detecting analyzers, it is characterized in that: also comprise at least one reagent storage unit 18, this reagent storage unit 18 is interior can place some detecting elements.
18, according to 17 described medical detecting analyzers, it is characterized in that: the storage chambers 15 in master control set 10 are optionally accommodated proving installation 100 or reagent storage unit 18, be that storage chamber 15 can not only be taken in proving installation 100, also can take in reagent storage unit 18.
19, according to any one described medical detecting analyzer of 12-15 and 17-18, it is characterized in that: wherein the testing result output unit comprises printer 14 and/or display 13.
20, according to any one described medical detecting analyzer of 12-15 and 17-18, it is characterized in that: wherein control device comprises touch-screen display 13, and this touch-screen display 13 provides operation interface.
21, according to any one described medical detecting analyzer of 12-15 and 17-18, it is characterized in that: also comprise the latching system of master control set 10 with proving installation 100 snap closes or release.
22, according to 21 described medical detecting analyzers, it is characterized in that: described latching system comprises three permanent magnet blocks, wherein the first and second magnetic patch are placed in the shell of master control set 10, the 3rd magnetic patch is fixed on the shell of proving installation 100, when proving installation is housed in the storage chamber 15 of master control set when interior fully, three magnetic patch are arranged in straight line substantially, the second magnetic patch is between the first and the 3rd magnetic patch, second opposite with the two relative utmost point magnetic of the 3rd magnetic patch (for example one is the S utmost point, another is the N utmost point), first two utmost point Magnetic Phase same (being all for example the N utmost point or the S utmost point) that magnetic patch is relative with the second magnetic patch, the first magnetic patch can move with the line of proving installation (100) along three magnetic patch.
Three of purpose of the present invention is to provide a kind of Biochemical Analyzer.
23, a kind of Biochemical Analyzer, it is characterized in that: comprise a master control set 10 and at least one proving installation 100, master control set 10 comprises at least one storage chamber 15, proving installation 100 is incorporated in described storage chamber 15, be designed with guide rail 16 in storage chamber 15, proving installation 100 is designed with slide block structure, and described slide block structure can be in the interior slip of guide rail 16 of storage chamber 15, thus reposefully with proving installation 100 from shifting out in storage chamber 15 or 100 groups of proving installations being entered in storage chamber 15.
24, according to 23 described Biochemical Analyzers, it is characterized in that: the two side of storage chamber 15 is designed with respectively guide rail 16, and perhaps the bottom design at storage chamber has guide rail 17, perhaps all is designed with guide rail in two side and the bottom of storage chamber.
25, according to 24 described Biochemical Analyzers, it is characterized in that: described slide block structure comprises the take-up housing 120 that designs in the side of proving installation base 101, is provided with slide block 121 in take-up housing 120, and described slide block 121 can be in the interior slip of guide rail 16 of storage chamber 15.
26, according to 24 described Biochemical Analyzers, it is characterized in that: described slide block structure comprises the take-up housing 120 that designs in the bottom of proving installation base 101, is provided with slide block 121 in take-up housing 120, and described slide block 121 can be in the interior movement of guide rail 17 of storage chamber 15.
27, according to 23 described Biochemical Analyzers, it is characterized in that: the proving installation 100 and the quantity storage chamber 15 that is no less than the proving installation number that comprise two or more.
28, according to 27 described Biochemical Analyzers, it is characterized in that: be separate work between described proving installation 100.
29, according to 23 described Biochemical Analyzers, it is characterized in that: also comprise at least one reagent storage unit 18, have at least a storage chamber 15 to be used for taking in reagent storage unit 18, remaining storage chamber is used for taking in proving installation 100.
30, according to 29 described Biochemical Analyzers, it is characterized in that: described reagent storage has reagent storage frame 19 in the unit.
31, according to any one described Biochemical Analyzer of 23 to 30, it is characterized in that: mutually fasten by magnetic block lock catch structure between described proving installation 100 or reagent storage frame 19 and master control set 10.
32, according to 31 described Biochemical Analyzers, it is characterized in that: described magnetic block lock catch structure comprises three permanent magnet blocks, wherein the first magnetic patch 151 and the second magnetic patch 152 are placed in the shell of master control set 10, the 3rd magnetic patch 153 is fixed on the shell of proving installation 100, when proving installation is housed in the storage chamber 15 of master control set when interior fully, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point magnetic of the second magnetic patch 152 and the 3rd magnetic patch 153 are opposite, and (for example one is the S utmost point, another is the N utmost point), first two utmost point Magnetic Phase same (being all for example the N utmost point or the S utmost point) that magnetic patch 151 is relative with the second magnetic patch 152, the first magnetic patch 151 can move along the line of three magnetic patch.
33, according to 32 described Biochemical Analyzers, it is characterized in that: the first magnetic patch 151 designs are on proving installation backboard 126, the second magnet piece 152 designs are in master control set 10, being designed with two bracing frames, 154, the three magnetic patch 153 on the master control set bonnet is connected with bracing frame 154 by spring leaf 155.
34, according to 23 described Biochemical Analyzers, it is characterized in that: master control set 10 also comprises primary power 11, master switch 12, guidance panel 13 and printer 14, and master switch 12, guidance panel 13 and printer 14 are electrically connected to primary power 11.
35, according to 23 described Biochemical Analyzers, it is characterized in that: master control set 10 also comprises usb 19, fan 20 and general supply access port 21.
36, according to 23 described Biochemical Analyzers, it is characterized in that: proving installation 100 comprises a base 101, the microscope carrier that transport test strip 102 of design on base 101, be positioned at the light source transmitter-receiver device 103 of microscope carrier 102 tops, at least fixedly be designed with a support on base 101, described light source transmitter-receiver device 103 designs are on described support, at least one side at microscope carrier 102 is designed with rack-plate 111 regularly, be designed with stepper motor 107 on described support, gear 108 on stepper motor is connected with a joggle with the rack-plate 111 on microscope carrier 102, the stepper motor driven gear rotates, the gear driven microscope carrier moves in proving installation.
37, according to 36 described Biochemical Analyzers, it is characterized in that: described light source transmitter-receiver device 103 comprises the optical coupled switch 132 of motor 130, light source emitter 131, optical pickup apparatus and control light source transmitter-receiver device movement position that promotion light source emitter 131 moves up and down.
38, according to 23 described Biochemical Analyzers, it is characterized in that: described master control set 10 and proving installation 100 electric connections.
39, according to 38 described Biochemical Analyzers, it is characterized in that: master control set 10 is connected by power connector 140 with proving installation 100.
Four of purpose of the present invention is to provide another kind of Biochemical Analyzer.
40, a kind of Biochemical Analyzer, comprise master control set 10 and the proving installation 100 that is electrically connected to master control set 10, it is characterized in that: master control set 10 comprises supply unit 11 and control device, and proving installation 100 comprises microscope carrier movably 102 and is positioned at the light source transmitter-receiver device 103 that can do on microscope carrier to approach and move away from microscope carrier.
41, according to 40 described Biochemical Analyzers, it is characterized in that: described control device comprises shell with master control set 10 by hinged guidance panel 13, the guidance panel 13 0-180 degree that can overturn take hinge as rotating shaft.
42, according to 41 described Biochemical Analyzers, it is characterized in that: the operation interface of described guidance panel 13 is downward, and when the 90-180 that overturns take hinge as rotating shaft when guidance panel 13 spent, its guidance panel 13 was in opening.
43, according to 41 described Biochemical Analyzers, it is characterized in that: the operation interface of described guidance panel 13 makes progress, and when the 0-90 that overturns take hinge as rotating shaft when guidance panel 13 spent, its guidance panel 13 was in opening.
44, according to 43 described Biochemical Analyzers, it is characterized in that: guidance panel 13 is provided with support 24, the two ends of support 24 make the angle of shell maintenance between between the 0-90 degree of guidance panel 13 and master control set 10 respectively against the shell of guidance panel 13 and master control set 10.
45, according to any one described Biochemical Analyzer of 40-44, it is characterized in that: described guidance panel 13 is LCD or LED display panel.
46, according to 45 described Biochemical Analyzers, it is characterized in that: described guidance panel 13 is touch-screen LCD or the LED display panels that can carry out touch screen operation.
47, according to any one described Biochemical Analyzer of 40-44, it is characterized in that: be provided with storage chamber 15 in master control set 10, proving installation 100 inserts storage chamber in the mode of drawer or extracts out from storage chamber.
48, according to 47 described Biochemical Analyzers, it is characterized in that: the outer wall of the inwall of storage chamber 15 and proving installation 100 is provided with the railroad that cooperatively interacts.
49, according to 48 described Biochemical Analyzers, it is characterized in that: rail structure comprises guide rail 16 and slide block structure 120, and described slide block structure can move on guide rail.
Five of purpose of the present invention is to provide a kind of magnetic block lock catch structure.
50, a kind of magnetic block lock catch structure, comprise at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on first device, the second magnetic patch 152 is fixed on the second device, the 3rd magnetic patch 153 is placed on the second device movably, when the first and second devices are in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 are with (being all for example the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch.
51, according to 50 described magnetic block lock catch structures, it is characterized in that: be designed with the spring leaf 155 that two supports 154 and two ends are movably attached to support 154 on the second device, described the 3rd magnetic patch 153 is fixedly connected with spring leaf 155.
52, according to 50 described magnetic block lock catch structures, it is characterized in that: be designed with two slide bars 156 on the second device and can slide on slide bar 156 by slide bar button 157 with slide bar button 157, the three magnetic patch 153 that are enclosed within on slide bar 156.
53, according to 50 described magnetic block lock catch structures, it is characterized in that: be designed with two springs, 158, the three magnetic patch 153 on the second device and be connected with spring 158 by snak link 159.
Six of purpose of the present invention is to provide a kind of magnetic block lock catch structure that utilizes and makes two devices mutual snap closes and the method for separating.
54, a kind of magnetic block lock catch structure that utilizes makes two devices mutual snap closes and the method for separating, described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on first device, the second magnetic patch 152 is fixed on the second device, the 3rd magnetic patch 153 is placed on the second device movably, when the first and second devices are in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 are with (being all for example the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch, described method comprises the steps: 1) first device that will be fixed with described the first magnetic patch 151 is close to the second device that is fixed with described the second magnetic patch 152, and make described the 3rd magnetic patch 153 and described the second magnetic patch 152 keep distance enough far away, the first magnetic patch 151 is in the same place by magnetic-adsorption with the second magnetic patch 152, thereby with first device and the second mutual snap close of device, 2) promotion the 3rd magnetic patch 153 is close to the second magnetic patch 152, mutual repulsive force between the 3rd magnetic patch 153 and the second magnetic patch 152 and the first magnetic patch 151, weaken the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 153, thereby first device and the second device are separated from each other.
Seven of purpose of the present invention is to provide a kind of Biochemical Analyzer with magnetic block lock catch structure.
55, a kind of Biochemical Analyzer with magnetic block lock catch structure, comprise master control set 10 and proving installation 100, be provided with storage chamber 15 in master control set 10, proving installation 100 is housed in storage chamber 15, it is characterized in that: described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on proving installation 100, the second magnetic patch 152 is fixed on master control set 10, the 3rd magnetic patch 153 is placed on master control set 10 movably, when master control set 10 and electricity testing device 100 are in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 are with (being all for example the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch.
56, according to 55 described Biochemical Analyzers, it is characterized in that: be designed with two bracing frames 154 on master control set 10) the 3rd magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.
57, according to 55 described Biochemical Analyzers, it is characterized in that: being designed with two slide bars, 156, the three magnetic patch 153 on master control set 10 can slide on slide bar 156 by slide bar button 157.
58, according to 55 described Biochemical Analyzers, it is characterized in that: be designed with two springs, 158, the three magnetic patch 153 on master control set 10 and mutually conflict by snak link 159 and spring 158.
Eight of purpose of the present invention is to provide a kind of method of testing that adopts Biochemical Analyzer to measure parameters of biological samples.
59, a kind of method of testing that adopts Biochemical Analyzer to measure parameters of biological samples, it is characterized in that: comprise the following steps: 1) opening power, Biochemical Analyzer are started shooting and are entered the startup self-detection step; 2) after startup self-detection was passed through, Biochemical Analyzer entered preheating step; 3) when the probe temperature of Biochemical Analyzer satisfies predefined temperature conditions, prompting is put into testing element and is detected sample; 4) Biochemical Analyzer starts test; 5) after test is completed, output test result; 6) prompting is taken out used testing element and is detected sample; 7) whether prompting detects and finishes; 8) if select not finish, prompting is put into new testing element and is detected sample, and then repeating step 4)-6); 9) if select to finish, shutdown finishes test.
60, according to 59 described method of testings, it is characterized in that: described Biochemical Analyzer comprises master control set 10 and at least one proving installation 100, and the startup self-detection step comprises whether the state that checks each equipment is normal, and the quantity of checkout device 100.
61, according to 60 described method of testings, it is characterized in that: when the quantity of proving installation 100 is equal to, or greater than two, after the step that startup self-detection is passed through, before preheating step, also comprise and select to open the step which platform or which platform proving installation 100 are tested.
62, according to 61 described method of testings, it is characterized in that: after having selected the step that proving installation 100 tests or after preheating step, also comprise the step that the test approaches that will carry out selected proving installation 100 is selected.
63, according to 61 described method of testings, it is characterized in that: after putting into testing element and detecting sample, before analyser starts test, comprise that also the test approaches that will carry out selected proving installation 100 carries out the step of automatic decision.
64, according to 63 described method of testings, it is characterized in that: be accompanied with the beacon information of test approaches on testing element, automatic decision test approaches after the beacon information on Biochemical Analyzer read test element.
65, according to 64 described method of testings, it is characterized in that: after each proving installation 100 was completed test, whether Biochemical Analyzer prompting test finished, finish if select, close this TV station proving installation 100, if do not carry out any selection, this TV station proving installation 100 cut out after the idle schedule time.
66, according to 65 described method of testings, it is characterized in that: after whole proving installation 100 cuts out, the Biochemical Analyzer shutdown.
67, according to 59 described method of testings, it is characterized in that: be provided with guide rail between the master control set 10 of Biochemical Analyzer and at least one proving installation 100, at least one proving installation 100 can be in the interior slip of master control set 10.
68, according to 67 described method of testings, it is characterized in that: Biochemical Analyzer also includes the appearance profile reagent storage unit identical or close with proving installation 100 with size 18, be provided with the storage chamber 15 that profile and size and proving installation 100 and reagent storage unit 18 are complementary in master control set 10, storage chamber can optionally be accommodated proving installation 100 or reagent storage unit 18, be that storage chamber 15 can not only be taken in proving installation 100, also can take in reagent storage unit 18.
69, according to 68 described method of testings, it is characterized in that: be provided with guide rail between reagent storage unit 18 and master control set 10.
Owing to adopting technique scheme, the present invention has brought following beneficial effect:
In proving installation by the slide block on proving installation mobile cooperation the in the master control set guide rail, can realize that proving installation is installed on master control set or with proving installation to disassemble from master control set.This operating process is simple, convenient.
Owing to can also taking in the reagent storage unit in storage chamber, the operator can be placed on the reagent of needs in the reagent rack of reagent storage unit in advance, just can take out easily the reagent that needs from described reagent storage frame during detection.If the proving installation of certain type is used for a long time, but its corresponding reagent storage unit also long-term storage in master control set, form man-to-man relation with proving installation, prevent from misusing reagent.The reagent storage unit is incorporated in master control set, makes operating table surface be unlikely to pile with reagent bottle, prevents the hazard events such as reagent bottle tipping.
Magnetic block lock catch structure of the present invention has utilized the two like magnetic poles attract each other of magnetic patch, the principle that the opposite sex is repelled each other, and has effectively realized the assembling between proving installation and master control set.Magnetic block lock catch structure of the present invention does not need the operator to use a lot of strength, does not need the operator to dismantle such as a lot of screw nut etc. yet, and whole process is very simple and convenient.
The rack-plate that utilizes the stepper motor driven wheel to drive on microscope carrier of the present invention moves, thereby drive the motion of test paper test paper carrier bench, not only improved test speed, and the driving effect of stepper motor continuous and stable, can stablize and accurately microscope carrier is transported to the tram.
The track base that the bottom of microscope carrier is designed with on guide rail and base is used in conjunction with, and makes level and smooth the moving in proving installation of microscope carrier energy, has reduced the interference of noise.
Baffle plate of the present invention not only plays good protection to the test strips microscope carrier in proving installation and light source transmitter-receiver device, makes microscope carrier and light source transmitter-receiver device avoid external force collision, prevents dust pollution.Simultaneously when proving installation is deposited separately, it is the structure of a sealing due to proving installation, when the sample when retention in the proving installation that is removed has test or test agent, reagent or sample residual on microscope carrier can not be exposed in external environment, prevent the pollution to surrounding environment and operator.
Biochemical Analyzer of the present invention also comprises the supporting structure for the support operation panel, when establishing, stent support is arranged thereafter due to guidance panel, and the operator is when using panel button, and guidance panel can not cave in backward.
Description of drawings
Fig. 1 Biochemical Analyzer schematic diagram;
Fig. 2 Biochemical Analyzer guidance panel open mode schematic diagram;
A view that proving installation is drawn out of in Fig. 3 Biochemical Analyzer;
The reagent storage cell schematics is arranged in Fig. 4 Biochemical Analyzer;
The rear structure schematic diagram of Fig. 5 Biochemical Analyzer and proving installation;
The guidance panel of Fig. 6 Biochemical Analyzer is by the second design diagram of stent support;
The proving installation inner structure schematic diagram of Fig. 7 Biochemical Analyzer;
The cut-open view of the proving installation of Fig. 8 Biochemical Analyzer A-A direction along the line;
The proving installation door of the proving installation of Fig. 9 Biochemical Analyzer is opened schematic diagram;
The schematic diagram that in Figure 10 the first magnetic block lock catch structure, the first magnetic patch and the second magnetic patch attract each other;
The first magnetic patch and the separated schematic diagram of the second magnetic patch in Figure 11 the first magnetic block lock catch structure;
Figure 12 the second magnetic block lock catch structure schematic diagram;
The third magnetic block lock catch structure schematic diagram of Figure 13;
Figure 14 Biochemical Analyzer test flow chart.
Embodiment
The present invention will be described in detail below in conjunction with concrete accompanying drawing.These specific embodiments are only limited the enumerating under spirit of the present invention, do not get rid of one of ordinary skill in the art prior art and the present invention in conjunction with and other specific embodiments of producing.
As shown in Figure 1, Biochemical Analyzer 1 of the present invention comprises a master control set 10 and separate proving installation 100 more than or, and master control set 10 is connected with wire by electric connector 140 with proving installation 100.Each proving installation 100 can according to the instruction of master control set 10 transmission, be completed test item and testing result is transferred to master control set 10 outputs independently of one another.Be designed to relatively independent relation between each proving installation 100, the dismounting that proving installation 100 can be freely carries out repeatedly with master control set 10.
, include in the casing of master control set 10 and power to the each several part of Biochemical Analyzer after primary power 11(connects the external goods electricity consumption to shown in Figure 6 as Fig. 1).Master control set 10 also includes master switch 12, guidance panel 13 and the printer 14 of analyser.Master switch 12, guidance panel 13 and printer 14 are electrically connected to primary power 11 respectively.Guidance panel 13 is touch display screens, both can show interface and the testing result of testing process, and the person's touch screen that is not convenient to operation again operates.
Be provided with side by side one or the storage chamber 15 that above size is substantially suitable with proving installation 100 in the casing of master control set 10.For proving installation can quick smoothly be pushed in the storage chamber 15 of master control set, at least the two side of storage chamber 15 is designed with respectively guide rail 16, perhaps the bottom design at storage chamber 15 has guide rail 17, perhaps all is designed with guide rail in two side and the bottom of storage chamber.Described guide rail coordinates with slide block or pulley (not shown) on proving installation.When proving installation is assembled into master control set or from the process that master control set disassembles, slide block or pulley on proving installation slide in guide rail, the guiding proving installation enters the storage chamber of master control set or leaves storage chamber 15.
As shown in Figure 4, also can put into the size and shape reagent storage unit substantially suitable with proving installation 100 18 in described storage chamber 15, described reagent storage unit 18 is interior can arrange one or more reagent storage frame 19, be used for depositing the testing element of test use, this testing element can be test agent or reagent barrel etc.The advantage of this design is, can be according to actual needs, and the whole installation testing devices 100 of storage chamber 15 in master control set 10, perhaps part installation testing device 100, other installation reagent storage unit 18, thus make design more flexible.Biochemical Analyzer 1 has as shown in Figure 4 comprised a master control set 10, two proving installations 100 and a reagent storage unit 18.As more changeable embodiment more, Biochemical Analyzer 1 can comprise a master control set 10, one to ten, the even proving installation more than ten 100 and one to ten, the arbitrarily combination according to need of the even reagent storage unit more than ten 18, and the quantity of proving installation 100 and storage unit 18.The reagent that the operator can need when detecting is placed in reagent storage frame 19 in advance.When detecting, the operator can be easily takes out corresponding reaction reagent from the reagent storage unit of analyser.If proving installation is used for a long time, but its corresponding reagent storage unit also long-term storage in master control set, form man-to-man relation with proving installation, prevent from misusing reagent.Reagent is all sorted out and is placed in the reagent storage unit in addition, makes operating table surface be unlikely to pile with reagent bottle, prevents the hazard events such as reagent bottle tipping.
Be equipped with USB interface 26, fan 20, general supply access port 21 etc. on the shell of master control set 10.For the proving installation 100 that is pushed into is stably remained in storage chamber 15, on the bonnet of master control set, the position of corresponding each proving installation can also comprise bonnet lock hole 22.
To shown in Figure 9, proving installation 100 comprises a base 101 as Fig. 7, transports microscope carrier 102 designs of test strip on base, and light source transmitter-receiver device 103 is positioned at the top of microscope carrier 102.Fixedly be designed with left socle 104 and right support 105 on base 101, the left and right support surrounds microscope carrier 102 within it.Light source transmitter-receiver device 103 is arranged on the support of left and right, perhaps fixedly is designed with upper bracket 106 on the support of left and right, and light source transmitter-receiver device 103 is installed on upper bracket 106.Microscope carrier 102 can move back and forth at predefined track; light source transmitter-receiver device 103 can near and away from microscope carrier 102, the motion track of microscope carrier 102 and light source transmitter-receiver device 103 or the extended line of motion track mutually intersect in same plane or the orthogonal projection in same plane intersects mutually.
Be designed with stepper motor 107 at least one support 104 or 105, gear 108 is housed on stepper motor.The microscope carrier 102 that transports test strip comprises for the pallet 110 that carries test strip 109.At least one side at microscope carrier 102 is designed with rack-plate 111 regularly.Rack-plate 111 engagements on described gear 108 and microscope carrier 102.When stepper motor is worked, order about driven wheel and rotate, and then order about rack-plate 111 and make linear running, thereby the microscope carrier that will be connected with rack-plate is delivered to test zone or withdrawed from from test zone.Stepper motor is higher to the ratio of precision of motion, therefore when the motion of gear driven rack-plate, has not only improved the speed of transporting test paper, and has improved stability and the accuracy of test.
The medium position of base 101 fixedly is designed with track base 112, guide rail 113 on this track base 112 and test strips microscope carrier 102 is used in conjunction with, microscope carrier 102 can slide along track base in proving installation, arrives the detection position or withdraws from test zone thereby transport test-strips.Described guide rail 113 designs in the bottom of microscope carrier 102.
A temperature control equipment 114 is arranged below the test zone that is positioned at test strips on microscope carrier.When the environment temperature of test does not meet predefined temperature range, temperature control equipment will be regulated temperature (for example heating) automatically, make the temperature of test environment meet predefined temperature range.Temperature control equipment comprises resistive heating device, and transmits temperature by potsherd or sheet metal.
The left and right sides of proving installation base 101 can also respectively be mounted with a take-up housing 120, and take-up housing 120 is bolted on base 101.The fixing design of slide block 121 is on take-up housing 120, this slide block 121 can be free to slide in the guide rail 16 of storage chamber 15 sidewalls, thereby drive whole proving installation in the interior movement of storage chamber 15, proving installation is pushed into storage chamber and prepares to carry out the detection of analyte, perhaps is moved out of storage chamber.Can also be arranged on the bottom of base with the take-up housing of slide block, be used in conjunction with bottom guide track 17 in storage chamber.As the change design, take-up housing 120 and slide block 121 can be also an integral body, can also be bars that matches with guide rail 16.
For better protection test microscope carrier and light source transmitter-receiver device, can also respectively be designed with baffle plate 122-126 all around, i.e. right baffle plate 122, right baffle-plate 123, overhead gage 124, front apron 125 and backboard 126 at proving installation 100.Be designed with a proving installation door 127 on front apron 125, proving installation door 127 can be connected through the hinge with front apron 125.When proving installation did not use or detecting, the proving installation door was closed.When the test strips microscope carrier in proving installation need to transport test strip, the proving installation door was opened, and the handled easily person deposits or take out test paper.Described baffle plate plays good protection to the test strips microscope carrier in proving installation and light source transmitter-receiver device, makes microscope carrier and light source transmitter-receiver device avoid external force collision, and can prevent dust pollution.When proving installation during by whole taking out, reagent or sample residual on microscope carrier can not be exposed in external environment, prevent the pollution to environment simultaneously.
Light source transmitter-receiver device 103 comprises the preferred stepper motor of electro-motor 130(that promotion light source transmitter-receiver device moves up and down), light source emitter 131.Light source transmitter-receiver device 103 also comprises the optical coupled switch 132 of controlling the light supply apparatus movement position, and described smooth lotus root switch 132 is electrically connected to described electro-motor 130, is used for controlling described electro-motor 130 operations and braking.Described smooth lotus root switch 132 has lightening hole 133, and the light source transmitter-receiver device has shutter 134.Described shutter 134 has the lightening hole of blocking 133 with respect to lightening hole 133 and leaves lightening hole 133 two positions.In the downward operational process of light source transmitter-receiver device, be positioned at lightening hole 133 tops of light lotus root switch 132 when shutter 134, this moment, light path was unimpeded, and power supply keeps power supply state always, and light supply apparatus continues to move downward under electro-motor 130 rotates.When shutter 134 had stopped the lightening hole 133 of light lotus root switch 132, light path was cut off, thereby closed the power supply of electro-motor 130, and light supply apparatus is no longer descending, opened simultaneously 131 pairs of samples of sample detection light source and carried out determination and analysis.
Each proving installation 100 can also comprise independently microprocessor, can carry out the movement position, test environment temperature and the heating plate heating supervisor that including but not limited to for example to control light source emitter, monitoring pallet, and by data transmission interface to extraneous the transmission of data.
Proving installation 100 also can comprise power interface and data transmission interface, realizes to proving installation power supply and test transmission result.Proving installation 100 is available integrated electric connector 140 also.Described electric connector is the device that power interface and data transmission interface are integrated, and this just makes proving installation have more space to deposit other accessories, has also reduced the operation of producing, and enhances productivity.Proving installation is connected with master control set by electric connector, accepts master control set proving installation is powered, or transfer data to the data output device of master control set.The electric connector of proving installation also can be connected on other data output device.
The detection light source that adopts on each proving installation can be identical or different.When the detection light source that adopts when a plurality of proving installations is identical, can improve speed and the efficient of detection.If the detection light source that proving installation adopts is different, each proving installation can be measured the identical or different biochemical parameter of identical or different samples, thereby realizes a tractor serves several purposes.The master control set that other are any and the array mode between proving installation are all suitable.
In order to guarantee that proving installation well is fixed on master control set, can arrange on proving installation and master control set proving installation is fixed to buckle structure on master control set.Described buckle structure can be fixed form, buckle snap close or the magnetic patch snap close of screw thread snap close (for example bolt and nut, screw and threaded hole).The structure of described magnetic patch snap close to shown in Figure 13, comprises at least three magnetic patch, the first magnetic patch 151, the second magnetic patch 152 and the 3rd magnetic patch 153 as Figure 10.The first magnetic patch 151 designs are on first device, and the second magnetic patch 152 and the 3rd magnetic patch 153 designs are on the second device.The magnetic of two faces that the first magnetic patch 151 is relative with the second magnetic patch 152 different (being respectively the S utmost point and the N utmost point), the Magnetic Phase of two faces that the second magnetic patch 152 is relative with the 3rd magnet 153 is with (be all the S utmost point or be all the N utmost point).The first magnetic patch 151, the second magnetic patch 152 and the 3rd magnetic patch 153 are roughly overlapping perpendicular to the projection on the direction of its opposite face.If with two mutual snap closes of device when living, to push to the second device of the second magnetic patch 152 close with the first device of the first magnetic patch 151, first device finally is in the same place by magnetic-adsorption with the second device, and at this moment, the 3rd magnetic patch 153 is away from the second magnetic patch 152.If two devices are separated from each other, it is close that push the 3rd magnetic patch 153 to second magnetic patch 152 this moment, utilize the mutual repulsive force between the 3rd magnetic patch 153 and the second magnetic patch 152 and the first magnetic patch 151, weakened the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 153, thereby first device and the second device are separated from each other.
Biochemical Analyzer of the present invention such as Figure 10 are to embodiment shown in Figure 11, and the first magnetic patch 151 designs are on the backboard 126 of proving installation 100.The second magnetic patch 152 is entrenched in the bonnet lock hole 22 of master control set 10.Be designed with two bracing frames 154 on the master control set bonnet, support frame as described above 154 designs respectively the both sides at bonnet lock hole.The 3rd magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.The magnetic of two faces that the first magnetic patch 151 is relative with the second magnetic patch 152 different (being respectively the S utmost point and the N utmost point), the Magnetic Phase of two faces that the second magnetic patch 152 is relative with the 3rd magnetic patch 153 is with (be all the S utmost point or be all the N utmost point).Shown in Figure 10 is the interior state of storage chamber 15 that proving installation 100 is pushed into master control set 10, at this moment, there is a natural attraction between the sexes because of magnet for the first magnetic patch 151 and the second magnetic patch 152, and this magnetic attraction makes proving installation be inhaled on master control set firmly, and can not skid off from master control set.As shown in figure 11, when needs are extracted proving installation 100 out, the 3rd magnetic patch 153 is pushed away to the second magnetic patch direction, because the polarity of two faces that the second magnetic patch 152 is relative with the 3rd magnetic patch 153 is identical, and the polarity of the face that the 3rd magnetic patch 153 is relative with the first magnetic patch 151 is also identical, according to the principle of the two like magnetic poles repel each other of magnet, the 3rd 153 pairs of magnetic patch the first magnetic patch and the second magnetic patch have a repulsive interaction, have weakened the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 152.Close along with the 3rd magnetic patch 153, this repulsive force can basic neutralisation the first magnetic patch 151 and the second magnetic patch 152 between magnetic attraction.Thereby proving installation 100 just can be extracted out from the storage chamber of master control set at an easy rate.
Figure 12 is the another kind of embodiment of magnetic block lock catch structure, and the 3rd magnetic patch 153 can slide on slide bar 156 by slide bar button 157.Figure 13 is the another kind of embodiment of magnetic block lock catch structure, and the 3rd magnetic patch 153 is conflicted mutually by snak link 159 and spring 158, and spring has the state that is compressed and unfold by the 3rd magnetic patch.
Between master control set and proving installation, testing process as shown in figure 14.Workflow is: opening power at first, Biochemical Analyzer is started shooting and is entered the startup self-detection program, after startup self-detection finishes, enters preheating program, when the probe temperature of Biochemical Analyzer meets predefined temperature range, detector is in the wait test mode, and the operator selects the proving installation that need to test, after putting into the test paper bar, analyser starts test, test outputs test result after finishing, and takes out the test paper bar.Again put into new test paper bar if also will carry out the detection of next sample, the mensuration of a beginning new round.If all samples has all been tested and has been completed, shutdown.
Claims (8)
1. proving installation that medical test is used, it is characterized in that: comprise base (101), design being used on base (101) transports the movably microscope carrier (102) of testing element and to be positioned at movably light source transmitter-receiver device (103) above microscope carrier (102), microscope carrier (102) can move back and forth at predefined track, light source transmitter-receiver device (103) can near and away from microscope carrier (102), the motion track of microscope carrier (102) and light source transmitter-receiver device (103) or the extended line of motion track mutually intersect in same plane or the orthogonal projection in same plane intersects mutually, when certain fixed area on microscope carrier (102) is positioned at orthogonal projection place of light source transmitter-receiver device (103) just, microscope carrier (102) stops mobile, then light source transmitter-receiver device (103) is near that fixed area on microscope carrier (102), detect, after detection is completed again away from that fixed area on microscope carrier (102).
2. proving installation according to claim 1 is characterized in that: proving installation also comprises at least one fixing design support on base (101), and described light source transmitter-receiver device (103) designs on described support.
3. proving installation according to claim 2, it is characterized in that: described proving installation comprises at least two motors, drives respectively described microscope carrier (102) and light source transmitter-receiver device (103).
4. proving installation according to claim 3, it is characterized in that: described electro-motor is stepper motor (107,130).
5. proving installation according to claim 4, it is characterized in that: be fixed with rack-plate (111) on microscope carrier (102), stepper motor (107) with gear (108) is arranged on described support, rack-plate (111) on gear on stepper motor (108) and microscope carrier (102) is connected with a joggle, and drives microscope carrier (102) mobile.
6. proving installation according to claim 2, it is characterized in that: described support comprises: left socle (104), right support (105), be designed with upper bracket (106) on described left socle and right support, light source transmitter-receiver device (103) designs on upper bracket (106).
7. proving installation that medical test is used, it is characterized in that: comprise base (101), design being used on base (101) transports the movably microscope carrier (102) of testing element and to be positioned at movably light source transmitter-receiver device (103) above microscope carrier (102), microscope carrier (102) can move back and forth at predefined track, light source transmitter-receiver device (103) can near and away from microscope carrier (102), the motion track of microscope carrier (102) and light source transmitter-receiver device (103) or the extended line of motion track mutually intersect in same plane or the orthogonal projection in same plane intersects mutually, light source transmitter-receiver device (103) comprises light source emitter (131), the optical coupled switch (132) that optical pickup apparatus and control light source transmitter-receiver device move, described optical coupled switch (132) has lightening hole (133), has shutter (134) on the light source transmitter-receiver device, described shutter (134) has the lightening hole of blocking (133) with respect to lightening hole (133) and leaves lightening hole (133) two positions.
8. proving installation according to claim 7, it is characterized in that: in the downward operational process of light source transmitter-receiver device (103), be positioned at lightening hole (133) top of optical coupled switch (132) when shutter (134), this moment, light path was unimpeded, power supply keeps power supply state always, make light source emitter (131) continue to move downward under electro-motor (130) rotates, when shutter (134) has stopped the lightening hole (133) of optical coupled switch (132), light path is cut off, thereby close the power supply of the electro-motor (130) of light source transmitter-receiver device (103), and open light source transmitter-receiver device (103) and carry out the analysis of sample.
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| CN 201110281722 CN102445414B (en) | 2011-09-21 | 2011-09-21 | Test device used for medical examination |
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| CN 201110281722 CN102445414B (en) | 2011-09-21 | 2011-09-21 | Test device used for medical examination |
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| CN202975023U (en) * | 2011-09-21 | 2013-06-05 | 艾康生物技术(杭州)有限公司 | Biochemical analysis test instrument |
| CN103912192B (en) * | 2014-01-27 | 2016-04-27 | 深圳市理邦精密仪器股份有限公司 | A kind of cabin door structure and apply its medical in-vitro diagnosis equipment |
| CN204330791U (en) * | 2014-11-06 | 2015-05-13 | 深圳市领治医学科技有限公司 | For the railroad that the test paper of automatic checkout equipment transmits |
| CN104713829A (en) * | 2015-03-16 | 2015-06-17 | 黄居梅 | Multifunctional test device for medical examination |
| CN105487569B (en) * | 2016-01-25 | 2017-07-07 | 广州北辰机电设备有限公司 | A kind of temperature control system based on sound wave thermometric |
| CN106405115B (en) * | 2016-11-18 | 2018-07-13 | 百奥森（江苏）食品安全科技有限公司 | The special colloidal-gold detecting-card of lactoferrin in a kind of detection tear |
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| US5408535A (en) * | 1993-09-07 | 1995-04-18 | Miles Inc. | Video test strip reader and method for evaluating test strips |
| CN2482082Y (en) * | 1999-12-10 | 2002-03-13 | 信息产业部电子第四十六研究所 | Polished surface detecting instrument |
| CN101666615A (en) * | 2008-09-05 | 2010-03-10 | 上海中晶科技有限公司 | Scanning head structure for detection device and detecting method thereof |
| JP2011149885A (en) * | 2010-01-25 | 2011-08-04 | Hitachi High-Technologies Corp | Automatic analyzer |
| CN202330251U (en) * | 2011-09-21 | 2012-07-11 | 艾康生物技术(杭州)有限公司 | Test device for medical technology |
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