CN202975023U - Biochemical analysis test instrument - Google Patents

Biochemical analysis test instrument Download PDF

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Publication number
CN202975023U
CN202975023U CN201220423576.5U CN201220423576U CN202975023U CN 202975023 U CN202975023 U CN 202975023U CN 201220423576 U CN201220423576 U CN 201220423576U CN 202975023 U CN202975023 U CN 202975023U
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China
Prior art keywords
test
magnetic patch
test cell
biochemical analysis
proving installation
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CN201220423576.5U
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Chinese (zh)
Inventor
唐林勇
商涛
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Acon Biotech Hangzhou Co Ltd
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Acon Biotech Hangzhou Co Ltd
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Priority claimed from CN2011102817102A external-priority patent/CN102374969A/en
Application filed by Acon Biotech Hangzhou Co Ltd filed Critical Acon Biotech Hangzhou Co Ltd
Priority to CN201220423576.5U priority Critical patent/CN202975023U/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor

Abstract

The utility model provides a biochemical analysis test instrument which comprises a machine shell, a test cell gate, a temperature control device, a mechanical movement control device and a light path detection device, wherein the test cell gate is internally provided with a magnetic induction starting device. According to the utility model, a test cell can not only effectively ensure that the test cell gate is closed when the test is started, but also eliminates the disturbance of an external light source by tightly closing the test cell gate without additionally adding other cell gate locking devices; and the test unit can be used for detecting a series of physiologic biochemical indexes, namely glucose, cholesterol, high-density fatty acid, low-density fatty acid, triglyceride, uric acid, bilirubin, total proteins, hemoglobin, acetone bodies, and the like.

Description

The biochemical analysis tester
Technical field
The utility model relates to biochemical analysis tester and the method for testing for biochemical analysis tester and method of testing, especially the Fast Measurement biochemical indicator of measuring the detection of clinical physiological index.
Background technology
Along with the progress of science and technology, the bedside in-vitro diagnosis experiment (POCT:Point of Care Testing) in the laboratory medicine field is arisen at the historic moment and is rapidly developed.20th century, " soak and read " dry chemical method (dip-and-read) of occurring of the fifties referred to the liquid detecting sample directly is added on the dry type reagent strip, moisture with sample causes specific chemical reaction on reagent strip as solvent, thereby carries out the method for sample analysis.Biochemical dry type test paper method also plays a significant role in fast detecting at the scene with characteristics such as its finding speed easy to carry, simple to operate are fast.Introduction along with immune response and molecular biotechnology, the check field of medical science dry type test paper method expands to the detection of blood sugar, gestation, blood coagulable status, myocardial damage, acid base equilibrium, infectious diseases etc., and medicine concentration monitor (TMD), alcohol content detection, thrombotest, the analysis of Blood Biochemical Indexes, infectious disease sieve, hormonal readiness and microchip DNA diagnosis and drug abuse detection etc. during operation.Rely on the testing result of ocular estimate judgement dry chemical test paper, can only be as qualitatively judging or semiquantitative judgement.Therefore for to make the interpretation of quick detection test paper more accurate, supporting miniaturization detecting instrument progressively grows up with it.These detecting instruments are easy and simple to handle, go out result fast, accurately.And the resulting data of these detecting instruments can also realize remote wireless transmission to the laboratory computer management system or form electronic health record.
US Patent No. 4780283 has disclosed a kind of dry chemical test paper analyser.This analyser comprises fixed detection light source, loads the hemispherical workbench of test paper bar.By the interaction between spring, hemispherical workbench being transported to the detection light source place detects.Due to the mechanicals efforts of just having utilized between spring, not only require to have very accurately control procedure on producing, increase production cost, and utilized the very difficult tram of controlling between reaction reagent bar and detection light source of interaction of spring, affected testing result.And hemispherical structure has increased the volume of whole analytical instrument.On the other hand, spring is short serviceable life, needs regular replacing spring, and this can make troubles to the user of instrument.
U.S. Praxsys Biosystems Inc. company has developed a kind of tachysynthesis detection system that can be used for quantitative and qualitative analysis judgement, disclose in US Patent No. 6136610, this system by detector and with it supporting Test paper box form.This system uses single channel, namely once only can detect single clinical samples.Because this detecting instrument once can only detect an index, so detection efficiency is lower.
Chinese patent application 200910160639.5 discloses a kind of multi-channel portable colloidal gold test paper device for quick testing, mainly comprises: 4 independently sense channel, ARM data processor, keyboard and LCD parts.The pick-up unit of this utility model can be completed multiple test item fast and high-throughout.But 4 of this Chinese patent application independently sense channel and whole detector be an integral body, the instrument user can not arbitrarily change test event by changing sense channel.
Chinese patent application 200410052202.7 discloses a kind of quick diagnosis lateral flow assays system and method, this detection system comprises 1 master unit and 1 to 20 test module, and being connected to host computer by USB or blue teeth wireless receiver, host computer moves by the software control detector.This patented claim also discloses and has been designed to relatively independent relation between master unit and test module, and when master unit broke down, all proving installations can be removed and ressemble with another master unit.It is a very complicated process that the described test module of this patented claim disassembles from master unit, needs a lot of parts of breakdown.On the other hand, described test module is not the structure of a sealing, when the sample when retention in the test module that is removed has test or test agent, the sample that these are residual or reagent can be exposed in environment, environment around not only having polluted also can consist of operating personnel's life security dangerous.
In existing detector, be all often single pass, namely once can only detect single patient's sample.This single pass detector is limited at the sample of unit interval build-in test, when processing the extensive health check-up of large contingent, tends to cause a large amount of delays of medical examiner.
In carrying out the application of sample process of sample detection, test paper first is placed on the experiment desktop, then drips sample.Because thereby test paper all can thinlyyer can tightly be bonded on laboratory table, when dripping sample, in the time of need to again picking up test paper, will be more difficult, need the more time of cost, incured loss through delay correct detection time.
On the other hand, if operator's error, in the situation that do not fasten test gate with regard to the open detection program, external interference light will enter and test the position like this, causes testing result inaccurate, particularly utilizes the detector of optical detection principle.
The utility model content
one of the purpose of this utility model is to provide the proving installation that a kind of medical test is used, this device comprises base 101, design was transported the movably microscope carrier 102 of testing element and to be positioned at movably light source transmitter-receiver device 103 above microscope carrier 102 in being used on base 101, microscope carrier 102 can move back and forth at predefined track, light source transmitter-receiver device 103 can near and away from microscope carrier 102, the motion track of microscope carrier 102 and light source transmitter-receiver device 103 or the extended line of motion track mutually intersect in same plane or the orthogonal projection in same plane intersects mutually.
Described proving installation, wherein, when certain fixed area on microscope carrier 102 is positioned at orthogonal projection place of light source transmitter-receiver device 103 just, microscope carrier 102 stops mobile, then light source transmitter-receiver device 103 is near that fixed area on microscope carrier 102, detect, detect complete after again away from that fixed area on microscope carrier 102.
Described proving installation, wherein, proving installation also comprises the support 104 of at least one fixing design on base 101, described light source transmitter-receiver device 103 designs are on described support 104.
Described proving installation, wherein, described proving installation comprises at least two motors, drives respectively described microscope carrier 102 and light source transmitter-receiver device 103.
Described proving installation, wherein, described electro-motor is stepper motor 107,130.
Described proving installation wherein, is fixed with rack-plate 111 on microscope carrier 102, be arranged on described support with the stepper motor 107 of gear 108, and the gear 108 on stepper motor is connected with a joggle with the rack-plate 111 on microscope carrier 102, drives microscope carrier 102 and moves.
Described proving installation wherein, is designed with left socle 104, right support 105 on base 101, be designed with upper bracket 106 on described left socle and right support, and 103 designs of light source transmitter-receiver device are on upper bracket 106.
Described proving installation, wherein, light source transmitter-receiver device 103 comprises the optical coupled switch 132 that light source emitter 131, optical pickup apparatus and control light source transmitter-receiver device move.
Described proving installation, wherein, described smooth lotus root switch 132 has lightening hole 133, has shutter 134 on the light source transmitter-receiver device, and described shutter 134 has the lightening hole of blocking 133 with respect to lightening hole 133 and leaves lightening hole 133 two positions.
Described proving installation, wherein, in the downward operational process of light source transmitter-receiver device 103, be positioned at lightening hole 133 tops of light lotus root switch 132 when shutter 134, this moment, light path was unimpeded, power supply keeps power supply state always, make light source emitter 131 continue to move downward under electro-motor 130 rotates, when shutter 134 has stopped the lightening hole 133 of light lotus root switch 132, light path is cut off, thereby close the power supply of the electro-motor 130 of light source transmitter-receiver device 103, and open light source transmitter-receiver device 103 and carry out the analysis of sample.
Described proving installation, wherein, base 101 fixedly is designed with track base 112, and microscope carrier 104 fixedly is designed with guide rail 113, and described guide rail 113 slides with track base 112 and makes up.
two of the purpose of this utility model is to provide a kind of medical detecting analyzer, comprise a master control set 10 and at least one proving installation 100, wherein, master control set 10 comprises supply unit 11, control device, testing result output unit and the storage chamber 15 that is no less than the proving installation number, proving installation 100 comprises the microscope carrier 102 and the light source transmitter-receiver device 103 that is positioned at microscope carrier 102 tops for carrying detecting element and detection sample, proving installation 100 be placed in the storage chamber 15 of master control set and with the supply unit 11 of master control set, control device and testing result output unit are electrically connected to, the microscope carrier 102 that control device is controlled proving installation moves back and forth in certain direction, light source transmitter-receiver device 103 do on the direction substantially vertical with microscope carrier 102 moving directions near and away from the movement of microscope carrier, and detect the change color parameter that is placed in the detecting element on microscope carrier 102, then this parameter is delivered to control device, after processing through control device, via testing result output unit output detections result.
Described medical detecting analyzer, wherein, proving installation 100 can repeated multiple times extraction and group enter master control device 10.
Described medical detecting analyzer wherein, is designed with rail structure between the inwall of the storage chamber 15 of the outer wall of proving installation 100 and master control set 10.
Described medical detecting analyzer, wherein, rail structure comprises guide rail 16 and the slide block structure 120 that is placed on storage chamber 15 inwalls and proving installation outer wall, described slide block structure 120 can be in the interior slip of guide rail 16 of storage chamber 15.
Described medical detecting analyzer comprises two or more proving installation 100, and each proving installation can detect the identical or different parameter that detects sample with kind, also can detect the identical or different parameter that variety classes detects sample.
Described medical detecting analyzer also comprises at least one reagent storage unit 18, and this reagent storage unit 18 is interior can place some detecting elements.
Described medical detecting analyzer, wherein, the storage chambers 15 in master control set 10 are optionally accommodated proving installation 100 or reagent storage unit 18, and namely storage chamber 15 can not only be taken in proving installation 100, also can take in reagent storage unit 18.
Described medical detecting analyzer, wherein, the testing result output unit comprises printer 14 and/or display 13.
Described medical detecting analyzer, wherein, control device comprises touch-screen display 13, this touch-screen display 13 provides operation interface.
Described medical detecting analyzer also comprises the latching system of master control set 10 with proving installation 100 snap closes or release.
described medical detecting analyzer, wherein, described latching system comprises three permanent magnet blocks, wherein the first and second magnetic patch are placed in the shell of master control set 10, the 3rd magnetic patch is fixed on the shell of proving installation 100, when proving installation is housed in the storage chamber 15 of master control set when interior fully, three magnetic patch are arranged in straight line substantially, the second magnetic patch is between the first and the 3rd magnetic patch, second opposite with the two relative utmost point magnetic of the 3rd magnetic patch (for example one is the S utmost point, another is the N utmost point), first two utmost point Magnetic Phase same (being all for example the N utmost point or the S utmost point) that magnetic patch is relative with the second magnetic patch, the first magnetic patch can move with the line of proving installation (100) along three magnetic patch.
Three of the purpose of this utility model is to provide a kind of Biochemical Analyzer, comprise a master control set 10 and at least one proving installation 100, master control set 10 comprises at least one storage chamber 15, proving installation 100 is incorporated in described storage chamber 15, be designed with guide rail 16 in storage chamber 15, proving installation 100 is designed with slide block structure, described slide block structure can be in the interior slip of guide rail 16 of storage chamber 15, thus reposefully with proving installation 100 from shifting out in storage chamber 15 or 100 groups of proving installations being entered in storage chamber 15.
Described Biochemical Analyzer, wherein, the two side of storage chamber 15 is designed with respectively guide rail 16, and perhaps the bottom design at storage chamber has guide rail 17, perhaps all is designed with guide rail in two side and the bottom of storage chamber.
Described Biochemical Analyzer, wherein, described slide block structure comprises the take-up housing 120 that designs in the side of proving installation base 101, is provided with slide block 121 in take-up housing 120, described slide block 121 can be in the interior slip of guide rail 16 of storage chamber 15.
Described Biochemical Analyzer, wherein, described slide block structure comprises the take-up housing 120 that designs in the bottom of proving installation base 101, is provided with slide block 121 in take-up housing 120, described slide block 121 can be in the interior movement of guide rail 17 of storage chamber 15.
Described Biochemical Analyzer comprises two or more proving installation 100 and the quantity storage chamber 15 that is no less than the proving installation number.
Described Biochemical Analyzer wherein, is separate work between described proving installation 100.
Described Biochemical Analyzer also comprises at least one reagent storage unit 18, has at least a storage chamber 15 to be used for taking in reagent storage unit 18, and remaining storage chamber is used for taking in proving installation 100.
Described Biochemical Analyzer, wherein, described reagent storage has reagent storage frame 19 in the unit.
Described Biochemical Analyzer wherein, fastens by magnetic block lock catch structure between described proving installation 100 or reagent storage frame 19 and master control set 10 mutually.
described Biochemical Analyzer, wherein, described magnetic block lock catch structure comprises three permanent magnet blocks, wherein the first magnetic patch 151 and the second magnetic patch 152 are placed in the shell of master control set 10, the 3rd magnetic patch 153 is fixed on the shell of proving installation 100, when proving installation is housed in the storage chamber 15 of master control set when interior fully, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point magnetic of the second magnetic patch 152 and the 3rd magnetic patch 153 are opposite, and (for example one is the S utmost point, another is the N utmost point), first two utmost point Magnetic Phase same (being all for example the N utmost point or the S utmost point) that magnetic patch 151 is relative with the second magnetic patch 152, the first magnetic patch 151 can move along the line of three magnetic patch.
Described Biochemical Analyzer, wherein, the first magnetic patch 151 designs are on proving installation backboard 126, and the second magnet piece 152 designs are in master control set 10, being designed with two bracing frames, 154, the three magnetic patch 153 on the master control set bonnet is connected with bracing frame 154 by spring leaf 155.
Described Biochemical Analyzer, wherein, master control set 10 also comprises primary power 11, master switch 12, guidance panel 13 and printer 14, master switch 12, guidance panel 13 and printer 14 are electrically connected to primary power 11.
Described Biochemical Analyzer, wherein, master control set 10 also comprises usb 19, fan 20 and general supply access port 21.
described Biochemical Analyzer, wherein, proving installation 100 comprises a base 101, the microscope carrier that transport test strip 102 of design on base 101, be positioned at the light source transmitter-receiver device 103 of microscope carrier 102 tops, at least fixedly be designed with a support on base 101, described light source transmitter-receiver device 103 designs are on described support, at least one side at microscope carrier 102 is designed with rack-plate 111 regularly, be designed with stepper motor 107 on described support, gear 108 on stepper motor is connected with a joggle with the rack-plate 111 on microscope carrier 102, the stepper motor driven gear rotates, the gear driven microscope carrier moves in proving installation.
Described Biochemical Analyzer, wherein, described light source transmitter-receiver device 103 comprises the optical coupled switch 132 of motor 130, light source emitter 131, optical pickup apparatus and control light source transmitter-receiver device movement position that promotion light source emitter 131 moves up and down.
Described Biochemical Analyzer, wherein, described master control set 10 and proving installation 100 electric connections.
Described Biochemical Analyzer, wherein, master control set 10 is connected by power connector 140 with proving installation 100.
Four of the purpose of this utility model is to provide another kind of Biochemical Analyzer, comprise master control set 10 and the proving installation 100 that is electrically connected to master control set 10, it is characterized in that: master control set 10 comprises supply unit 11 and control device, and proving installation 100 comprises microscope carrier movably 102 and is positioned at the light source transmitter-receiver device 103 that can do on microscope carrier to approach and move away from microscope carrier.
Described Biochemical Analyzer, wherein, described control device comprises shell with master control set 10 by hinged guidance panel 13, the guidance panel 13 0-180 degree that can overturn take hinge as rotating shaft.
Described Biochemical Analyzer, wherein, the operation interface of described guidance panel 13 is downward, and when the 90-180 that overturns take hinge as rotating shaft when guidance panel 13 spent, its guidance panel 13 was in opening.
Described Biochemical Analyzer, wherein, the operation interface of described guidance panel 13 makes progress, and when the 0-90 that overturns take hinge as rotating shaft when guidance panel 13 spent, its guidance panel 13 was in opening.
Described Biochemical Analyzer, wherein, guidance panel 13 is provided with support 24, and the two ends of support 24 make the angle of shell maintenance between between the 0-90 degree of guidance panel 13 and master control set 10 respectively against the shell of guidance panel 13 and master control set 10.
Described Biochemical Analyzer, wherein, described guidance panel 13 is LCD or LED display panel.
Described Biochemical Analyzer, wherein, described guidance panel 13 is touch-screen LCD or the LED display panels that can carry out touch screen operation.
Described Biochemical Analyzer wherein, is provided with storage chamber 15 in master control set 10, proving installation 100 inserts storage chamber in the mode of drawer or extracts out from storage chamber.
Described Biochemical Analyzer, wherein, the outer wall of the inwall of storage chamber 15 and proving installation 100 is provided with the railroad that cooperatively interacts.
Described Biochemical Analyzer, wherein, rail structure comprises guide rail 16 and slide block structure 120, described slide block structure can move on guide rail.
five of the purpose of this utility model is to provide a kind of magnetic block lock catch structure, comprise at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on first device, the second magnetic patch 152 is fixed on the second device, the 3rd magnetic patch 153 is placed on the second device movably, when the first and second devices are in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 are with (being all for example the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch.
Described magnetic block lock catch structure wherein, is designed with the spring leaf 155 that two supports 154 and two ends are movably attached to support 154 on the second device, described the 3rd magnetic patch 153 is fixedly connected with spring leaf 155.
Described magnetic block lock catch structure wherein, is designed with two slide bars 156 and can slides on slide bar 156 by slide bar button 157 with slide bar button 157, the three magnetic patch 153 that are enclosed within on slide bar 156 on the second device.
Described magnetic block lock catch structure wherein, is designed with two springs, 158, the three magnetic patch 153 and is connected with spring 158 by snak link 159 on the second device.
six of the purpose of this utility model is to provide a kind of magnetic block lock catch structure that utilizes and makes two devices mutual snap closes and the method for separating, described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on first device, the second magnetic patch 152 is fixed on the second device, the 3rd magnetic patch 153 is placed on the second device movably, when the first and second devices are in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 are with (being all for example the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch, described method comprises the steps: 1) first device that will be fixed with described the first magnetic patch 151 is close to the second device that is fixed with described the second magnetic patch 152, and make described the 3rd magnetic patch 153 and described the second magnetic patch 152 keep distance enough far away, the first magnetic patch 151 is in the same place by magnetic-adsorption with the second magnetic patch 152, thereby with first device and the second mutual snap close of device, 2) promotion the 3rd magnetic patch 153 is close to the second magnetic patch 152, mutual repulsive force between the 3rd magnetic patch 153 and the second magnetic patch 152 and the first magnetic patch 151, weaken the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 153, thereby first device and the second device are separated from each other.
seven of the purpose of this utility model is to provide a kind of Biochemical Analyzer with magnetic block lock catch structure, comprise master control set 10 and proving installation 100, be provided with storage chamber 15 in master control set 10, proving installation 100 is housed in storage chamber 15, it is characterized in that: described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on proving installation 100, the second magnetic patch 152 is fixed on master control set 10, the 3rd magnetic patch 153 is placed on master control set 10 movably, when master control set 10 and electricity testing device 100 are in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 are with (being all for example the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch.
Described Biochemical Analyzer wherein, is designed with two bracing frames 154 on master control set 10) the 3rd magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.
Described Biochemical Analyzer, wherein, being designed with two slide bars, 156, the three magnetic patch 153 on master control set 10 can slide on slide bar 156 by slide bar button 157.
Described Biochemical Analyzer wherein, is designed with two springs, 158, the three magnetic patch 153 and mutually conflicts by snak link 159 and spring 158 on master control set 10.
Eight of the purpose of this utility model is to provide a kind of method of testing that adopts Biochemical Analyzer to measure parameters of biological samples, and this method of testing comprises the following steps: 1) opening power, Biochemical Analyzer are started shooting and entered the startup self-detection step; 2) after startup self-detection was passed through, Biochemical Analyzer entered preheating step; 3) when the probe temperature of Biochemical Analyzer satisfies predefined temperature conditions, prompting is put into testing element and is detected sample; 4) Biochemical Analyzer starts test; 5) after test is completed, output test result; 6) prompting is taken out used testing element and is detected sample; 7) whether prompting detects and finishes; 8) if select not finish, prompting is put into new testing element and is detected sample, and then repeating step 4)-6); 9) if select to finish, shutdown finishes test.
Described method of testing, wherein, described Biochemical Analyzer comprises master control set 10 and at least one proving installation 100, the startup self-detection step comprises whether the state that checks each equipment is normal, and the quantity of checkout device 100.
Described method of testing wherein, when the quantity of proving installation 100 is equal to, or greater than two, after the step that startup self-detection is passed through, before preheating step, also comprises and selects to open the step which platform or which platform proving installation 100 are tested.
Described method of testing wherein, after having selected the step that proving installation 100 tests or after preheating step, also comprises the step that the test approaches that will carry out selected proving installation 100 is selected.
Described method of testing wherein, after putting into testing element and detecting sample, before analyser starts test, comprises that also the test approaches that will carry out selected proving installation 100 carries out the step of automatic decision.
Described method of testing wherein, is accompanied with the beacon information of test approaches on testing element, automatic decision test approaches after the beacon information on Biochemical Analyzer read test element.
Described method of testing, wherein, after each proving installation 100 is completed test, whether Biochemical Analyzer prompting test finishes, if select to finish, closes this TV station proving installation 100, if do not carry out any selection, this TV station proving installation 100 cut out after the idle schedule time.
Described method of testing, wherein, after whole proving installation 100 cuts out, the Biochemical Analyzer shutdown.
Described method of testing wherein, is provided with guide rail between the master control set 10 of Biochemical Analyzer and at least one proving installation 100, and at least one proving installation 100 can be in the interior slip of master control set 10.
Described method of testing, wherein, Biochemical Analyzer also includes the appearance profile reagent storage unit identical or close with proving installation 100 with size 18, be provided with the storage chamber 15 that profile and size and proving installation 100 and reagent storage unit 18 are complementary in master control set 10, storage chamber can optionally be accommodated proving installation 100 or reagent storage unit 18, be that storage chamber 15 can not only be taken in proving installation 100, also can take in reagent storage unit 18.
Described method of testing wherein, is provided with guide rail between reagent storage unit 18 and master control set 10.
nine of the purpose of this utility model is to provide a kind of biochemical analysis tester, comprise main control unit and at least two separate test cells, main control unit respectively with the general supply gauge tap, data input/output control system and test cell interconnect, each test cell comprises sample conveying device and light supply apparatus at least, described light supply apparatus comprises testing light source and top board, sample conveying device comprises the test paper pallet, the electro-motor of push to test test paper tray motion and the switch of controlling test paper pallet arrival detection position, described test paper pallet is provided with heating arrangement.
Described biochemical analysis tester is equipped with a test cell door corresponding to each test cell, and the operation of closing certain test cell door can automatically start its corresponding test cell and carry out work.
Described biochemical analysis tester is provided with magnetic induction start device in each test cell, this magnetic induction start device comprises the magnetic patch that is arranged on the test cell door and is arranged on the interior magnetic induction switch of test cell.
Described biochemical analysis tester comprises for the fixing casing of main control unit and test cell, test paper application of sample operator's console is housed on this casing.
Described biochemical analysis tester, its test paper operator's console is the structure of a draw-in groove, comprises upper plate and lower plate, leaves the gap between upper plate and lower plate and is fit to test paper ground insertion.
Described biochemical analysis tester, the switch that its control test paper pallet arrives the detection position is optical coupled switch.
Ten of the purpose of this utility model is to provide a kind of biochemical analysis method of testing, comprising:
1) open the biochemical analysis tester, and test parameter is set, described biochemical analysis tester comprises main control unit and at least two separate test cells, main control unit interconnects with general supply gauge tap, data input/output control system and test cell respectively, and each test cell comprises sample conveying device and testing light source device;
The test paper that 2) will add sample is put into one of them test cell;
3) the biochemical analysis tester judges whether detection zone has test paper to exist;
4) the biochemical analysis tester judges whether the test cell door closes;
5) when test paper Already in detection zone and cell gate closed these two groups of information when all possessing, the biochemical analysis tester begins start detection and output detections result.
Described method of testing, wherein, the biochemical analysis tester also can just detect the start time and whether surpass the time that presets and judge; If overtime, the biochemical analysis tester provides the information of again changing test paper; If not overtime, the biochemical analysis tester begins start detection and output detections result.
Described method of testing, wherein, testing light source sends test light, and judges by the reflected light information of pallet detection zone whether detection zone has test paper to exist; If no, the biochemical analysis tester provides the information that reapposes test paper.
Described method of testing, wherein, be provided with magnetic induction start device in test cell, magnetic induction switch is sensed the field signal of magnetic patch on cell gate, after field signal is delivered to main control unit, main control unit is judged the particular location of cell gate, if cell gate does not cut out, the biochemical analysis tester provides the information of closing unit door again.
11 of the purpose of this utility model is to provide a kind of biochemical analysis tester, the test cell that comprises casing, fixes with casing, the test cell door corresponding with test cell, wherein test cell includes temperature control equipment, mechanical motion control device and detects light path device, it is characterized in that, test cell and the test cell door corresponding with it are provided with by closing the test cell door and automatically start the magnetic induction start device that test cell carries out work.
Described biochemical analysis tester, wherein, magnetic induction start device comprises the magnetic patch that is arranged on the test cell door and is arranged on the interior magnetic induction switch of test cell, when closing the test cell door, magnetic patch on the test cell door is near the magnetic induction switch that is arranged in test cell, thereby open this magnetic induction switch, and then the startup test cell carries out work.
Described biochemical analysis tester, wherein, described magnetic patch material is magnet steel.
Described biochemical analysis tester, wherein, the mode that described magnetic patch is fixed with viscose or screw state is fixed is fixed on cell gate.
Described biochemical analysis tester, wherein, magnetic patch is closed in cell gate or is placed on outside cell gate.
Described biochemical analysis tester, wherein, described sample conveying device comprises that carrying detects the pallet of test paper, one heat transfer plate is arranged below pallet, by this heat transfer plate, the heat that heating arrangement produces is delivered to surveyed area, intercept at this having placed the heat that a lower lock block thermal insulation board produces on heating arrangement below temperature-adjusting heating device, electro-motor is fixed on the electro-motor fixed head, promotes pallet and will detect test bar and deliver to predefined detection position.
Described biochemical analysis tester also comprises for the optical coupled switch of controlling the predefined detection position of pallet arrival.
Described biochemical analysis tester, wherein, described heating arrangement is selected from the power resistor plate.
Described biochemical analysis tester comprises at least two test cells, and each test cell is corresponding to a described test cell door and a described magnetic induction start device.
12 of the purpose of this utility model is to provide a kind of biochemical analysis tester, comprises casing and is arranged on casing interior main control unit and test cell, it is characterized in that, test paper application of sample operator's console is housed on casing.
Described biochemical analysis tester, wherein, operator's console is the structure of a draw-in groove type.
Described biochemical analysis tester, wherein, operator's console is comprised of upper plate and lower plate, and leaves the gap between upper plate and lower plate, is fit to the insertion of test paper.
Described biochemical analysis tester comprises two separate test cells at least.
Owing to adopting technique scheme, the utility model has brought following beneficial effect:
In proving installation by the slide block on proving installation mobile cooperation the in the master control set guide rail, can realize that proving installation is installed on master control set or with proving installation to disassemble from master control set.This operating process is simple, convenient.
Owing to can also taking in the reagent storage unit in storage chamber, the operator can be placed on the reagent of needs in the reagent rack of reagent storage unit in advance, just can take out easily the reagent that needs from described reagent storage frame during detection.If the proving installation of certain type is used for a long time, but its corresponding reagent storage unit also long-term storage in master control set, form man-to-man relation with proving installation, prevent from misusing reagent.The reagent storage unit is incorporated in master control set, makes operating table surface be unlikely to pile with reagent bottle, prevents the hazard events such as reagent bottle tipping.
Magnetic block lock catch structure described in the utility model has utilized the two like magnetic poles attract each other of magnetic patch, the principle that the opposite sex is repelled each other, and has effectively realized the assembling between proving installation and master control set.Magnetic block lock catch structure described in the utility model does not need the operator to use a lot of strength, does not need the operator to dismantle such as a lot of screw nut etc. yet, and whole process is very simple and convenient.
The rack-plate that utilizes the stepper motor driven wheel to drive on microscope carrier described in the utility model moves, thereby drive the motion of test paper carrier bench, not only improved test speed, and the driving effect of stepper motor continuous and stable, can stablize and accurately microscope carrier is transported to the tram.
The track base that the bottom of microscope carrier is designed with on guide rail and base is used in conjunction with, and makes level and smooth the moving in proving installation of microscope carrier energy, has reduced the interference of noise.
Baffle plate described in the utility model not only plays good protection to the test strips microscope carrier in proving installation and light source transmitter-receiver device, makes microscope carrier and light source transmitter-receiver device avoid external force collision, prevents dust pollution.Simultaneously when proving installation is deposited separately, it is the structure of a sealing due to proving installation, when the sample when retention in the proving installation that is removed has test or test agent, reagent or sample residual on microscope carrier can not be exposed in external environment, prevent the pollution to surrounding environment and operator.
Biochemical Analyzer of the present utility model also comprises the supporting structure for the support operation panel, when establishing, stent support is arranged thereafter due to guidance panel, and the operator is when using panel button, and guidance panel can not cave in backward.
The beneficial effects of the utility model also comprise: 1) Biochemical Analyzer described in the utility model adopts the pattern of a plurality of separate test cells, has increased the sample size of unit interval build-in test, improves detection efficiency.2) method of testing described in the utility model has comprised a plurality of determining steps, has improved the accuracy that detects, and has reduced the inaccurate risk of test result that the manual operation mistake causes.3) comprised a magnetic induction start device at test cell described in the utility model, not only can effectively guarantee like this when starting test, the test cell door is closed, also do not need simultaneously additionally to add other unit lock locking devices, just the test cell door can be closed closely, get rid of the interference of external light source.4) Biochemical Analyzer described in the utility model, due to test paper application of sample operator's console being installed on instrument, the bottom surface of test paper being affectedly bashful the position does not touch the experiment desktop, makes the operator more easily be affectedly bashful the test paper that has added sample.
Description of drawings
Fig. 1 Biochemical Analyzer schematic diagram;
Fig. 2 Biochemical Analyzer guidance panel open mode schematic diagram;
A view that proving installation is drawn out of in Fig. 3 Biochemical Analyzer;
The reagent storage cell schematics is arranged in Fig. 4 Biochemical Analyzer;
The rear structure schematic diagram of Fig. 5 Biochemical Analyzer and proving installation;
The guidance panel of Fig. 6 Biochemical Analyzer is by the second design diagram of stent support;
The proving installation inner structure schematic diagram of Fig. 7 Biochemical Analyzer;
The cut-open view of the proving installation of Fig. 8 Biochemical Analyzer A-A direction along the line;
The proving installation door of the proving installation of Fig. 9 Biochemical Analyzer is opened schematic diagram;
The schematic diagram that in Figure 10 the first magnetic block lock catch structure, the first magnetic patch and the second magnetic patch attract each other;
The first magnetic patch and the separated schematic diagram of the second magnetic patch in Figure 11 the first magnetic block lock catch structure;
Figure 12 the second magnetic block lock catch structure schematic diagram;
The third magnetic block lock catch structure schematic diagram of Figure 13;
Figure 14 Biochemical Analyzer test flow chart.
Figure 15 is the schematic diagram of another embodiment of the utility model biochemical analysis tester.
Figure 16 is the test cell door open mode schematic diagram of biochemical analysis tester shown in Figure 15.
Figure 17 is biochemical analysis tester sectional view shown in Figure 15.
Figure 18 is test cell sectional view in biochemical analysis tester shown in Figure 15.
Figure 19 is magnetic induction switch and the magnetic patch positional structure schematic diagram on test cell door shown in Figure 16.
Figure 20 is the hardware composition diagram of Biochemical Analyzer shown in Figure 15.
Figure 21 is the method for testing process flow diagram of Biochemical Analyzer shown in Figure 15.
Embodiment
Below in conjunction with concrete accompanying drawing, the utility model is described in detail.These specific embodiments are only limited the enumerating under the utility model spirit, do not get rid of one of ordinary skill in the art prior art and the utility model in conjunction with and other specific embodiments of producing.
As shown in Figure 1, Biochemical Analyzer 1 described in the utility model comprises a master control set 10 and separate proving installation 100 more than or, and master control set 10 is connected with wire by electric connector 140 with proving installation 100.Each proving installation 100 can according to the instruction of master control set 10 transmission, be completed test item and testing result is transferred to master control set 10 outputs independently of one another.Be designed to relatively independent relation between each proving installation 100, the dismounting that proving installation 100 can be freely carries out repeatedly with master control set 10.
, include in the casing of master control set 10 and power to the each several part of Biochemical Analyzer after primary power 11(connects the external goods electricity consumption to shown in Figure 6 as Fig. 1).Master control set 10 also includes master switch 12, guidance panel 13 and the printer 14 of analyser.Master switch 12, guidance panel 13 and printer 14 are electrically connected to primary power 11 respectively.Guidance panel 13 is touch display screens, both can show interface and the testing result of testing process, and the person's touch screen that is not convenient to operation again operates.
Be provided with side by side one or the storage chamber 15 that above size is substantially suitable with proving installation 100 in the casing of master control set 10.For proving installation can quick smoothly be pushed in the storage chamber 15 of master control set, at least the two side of storage chamber 15 is designed with respectively guide rail 16, perhaps the bottom design at storage chamber 15 has guide rail 17, perhaps all is designed with guide rail in two side and the bottom of storage chamber.Described guide rail coordinates with slide block or pulley (not shown) on proving installation.When proving installation is assembled into master control set or from the process that master control set disassembles, slide block or pulley on proving installation slide in guide rail, the guiding proving installation enters the storage chamber of master control set or leaves storage chamber 15.
As shown in Figure 4, also can put into the size and shape reagent storage unit substantially suitable with proving installation 100 18 in described storage chamber 15, described reagent storage unit 18 is interior can arrange one or more reagent storage frame 19, be used for depositing the testing element of test use, this testing element can be test agent or reagent barrel etc.The advantage of this design is, can be according to actual needs, and the whole installation testing devices 100 of storage chamber 15 in master control set 10, perhaps part installation testing device 100, other installation reagent storage unit 18, thus make design more flexible.Biochemical Analyzer 1 has as shown in Figure 4 comprised a master control set 10, two proving installations 100 and a reagent storage unit 18.As more changeable embodiment more, Biochemical Analyzer 1 can comprise a master control set 10, one to ten, the even proving installation more than ten 100 and one to ten, the arbitrarily combination according to need of the even reagent storage unit more than ten 18, and the quantity of proving installation 100 and storage unit 18.The reagent that the operator can need when detecting is placed in reagent storage frame 19 in advance.When detecting, the operator can be easily takes out corresponding reaction reagent from the reagent storage unit of analyser.If proving installation is used for a long time, but its corresponding reagent storage unit also long-term storage in master control set, form man-to-man relation with proving installation, prevent from misusing reagent.Reagent is all sorted out and is placed in the reagent storage unit in addition, makes operating table surface be unlikely to pile with reagent bottle, prevents the hazard events such as reagent bottle tipping.
Be equipped with USB interface 26, fan 20, general supply access port 21 etc. on the shell of master control set 10.For the proving installation 100 that is pushed into is stably remained in storage chamber 15, on the bonnet of master control set, the position of corresponding each proving installation can also comprise bonnet lock hole 22.
Guidance panel 13 can be that LCD, LED touch panel or some have LCD, the LED panel of button.Guidance panel 13 is connected with master control set 10 by hinge 23, also can pass through hinge (not shown) and be connected with support and be connected with master control set 10.
To shown in Figure 9, proving installation 100 comprises a base 101 as Fig. 7, transports microscope carrier 102 designs of test strip on base, and light source transmitter-receiver device 103 is positioned at the top of microscope carrier 102.Fixedly be designed with left socle 104 and right support 105 on base 101, the left and right support surrounds microscope carrier 102 within it.Light source transmitter-receiver device 103 is arranged on the support of left and right, perhaps fixedly is designed with upper bracket 106 on the support of left and right, and light source transmitter-receiver device 103 is installed on upper bracket 106.Microscope carrier 102 can move back and forth at predefined track; light source transmitter-receiver device 103 can near and away from microscope carrier 102, the motion track of microscope carrier 102 and light source transmitter-receiver device 103 or the extended line of motion track mutually intersect in same plane or the orthogonal projection in same plane intersects mutually.
Be designed with stepper motor 107 at least one support 104 or 105, gear 108 is housed on stepper motor.The microscope carrier 102 that transports test strip comprises for the pallet 110 that carries test strip 109.At least one side at microscope carrier 102 is designed with rack-plate 111 regularly.Rack-plate 111 engagements on described gear 108 and microscope carrier 102.When stepper motor is worked, order about driven wheel and rotate, and then order about rack-plate 111 and make linear running, thereby the microscope carrier that will be connected with rack-plate is delivered to test zone or withdrawed from from test zone.Stepper motor is higher to the ratio of precision of motion, therefore when the motion of gear driven rack-plate, has not only improved the speed of transporting test paper, and has improved stability and the accuracy of test.
The medium position of base 101 fixedly is designed with track base 112, guide rail 113 on this track base 112 and test strips microscope carrier 102 is used in conjunction with, microscope carrier 102 can slide along track base in proving installation, arrives the detection position or withdraws from test zone thereby transport test-strips.Described guide rail 113 designs in the bottom of microscope carrier 102.
A temperature control equipment 114 is arranged below the test zone that is positioned at test strips on microscope carrier.When the environment temperature of test does not meet predefined temperature range, temperature control equipment will be regulated temperature (for example heating) automatically, make the temperature of test environment meet predefined temperature range.Temperature control equipment comprises resistive heating device, and transmits temperature by potsherd or sheet metal.
The left and right sides of proving installation base 101 can also respectively be mounted with a take-up housing 120, and take-up housing 120 is bolted on base 101.The fixing design of slide block 121 is on take-up housing 120, this slide block 121 can be free to slide in the guide rail 16 of storage chamber 15 sidewalls, thereby drive whole proving installation in the interior movement of storage chamber 15, proving installation is pushed into storage chamber and prepares to carry out the detection of analyte, perhaps is moved out of storage chamber.Can also be arranged on the bottom of base with the take-up housing of slide block, be used in conjunction with bottom guide track 17 in storage chamber.As the change design, take-up housing 120 and slide block 121 can be also an integral body, can also be bars that matches with guide rail 16.
For better protection test microscope carrier and light source transmitter-receiver device, can also respectively be designed with baffle plate 122-126 all around, i.e. right baffle plate 122, right baffle-plate 123, overhead gage 124, front apron 125 and backboard 126 at proving installation 100.Be designed with a proving installation door 127 on front apron 125, proving installation door 127 can be connected through the hinge with front apron 125.When proving installation did not use or detecting, the proving installation door was closed.When the test strips microscope carrier in proving installation need to transport test strip, the proving installation door was opened, and the handled easily person deposits or take out test paper.Described baffle plate plays good protection to the test strips microscope carrier in proving installation and light source transmitter-receiver device, makes microscope carrier and light source transmitter-receiver device avoid external force collision, and can prevent dust pollution.When proving installation during by whole taking out, reagent or sample residual on microscope carrier can not be exposed in external environment, prevent the pollution to environment simultaneously.
Light source transmitter-receiver device 103 comprises the preferred stepper motor of electro-motor 130(that promotion light source transmitter-receiver device moves up and down), light source emitter 131.Light source transmitter-receiver device 103 also comprises the optical coupled switch 132 of controlling the light supply apparatus movement position, and described smooth lotus root switch 132 is electrically connected to described electro-motor 130, is used for controlling described electro-motor 130 operations and braking.Described smooth lotus root switch 132 has lightening hole 133, and the light source transmitter-receiver device has shutter 134.Described shutter 134 has the lightening hole of blocking 133 with respect to lightening hole 133 and leaves lightening hole 133 two positions.In the downward operational process of light source transmitter-receiver device, be positioned at lightening hole 133 tops of light lotus root switch 132 when shutter 134, this moment, light path was unimpeded, and power supply keeps power supply state always, and light supply apparatus continues to move downward under electro-motor 130 rotates.When shutter 134 had stopped the lightening hole 133 of light lotus root switch 132, light path was cut off, thereby closed the power supply of electro-motor 130, and light supply apparatus is no longer descending, opened simultaneously 131 pairs of samples of sample detection light source and carried out determination and analysis.
Each proving installation 100 can also comprise independently microprocessor, can carry out the movement position, test environment temperature and the heating plate heating supervisor that including but not limited to for example to control light source emitter, monitoring pallet, and by data transmission interface to extraneous the transmission of data.
Proving installation 100 also can comprise power interface and data transmission interface, realizes to proving installation power supply and test transmission result.Proving installation 100 is available integrated electric connector 140 also.Described electric connector is the device that power interface and data transmission interface are integrated, and this just makes proving installation have more space to deposit other accessories, has also reduced the operation of producing, and enhances productivity.Proving installation is connected with master control set by electric connector, accepts master control set proving installation is powered, or transfer data to the data output device of master control set.The electric connector of proving installation also can be connected on other data output device.
The detection light source that adopts on each proving installation can be identical or different.When the detection light source that adopts when a plurality of proving installations is identical, can improve speed and the efficient of detection.If the detection light source that proving installation adopts is different, each proving installation can be measured the identical or different biochemical parameter of identical or different samples, thereby realizes a tractor serves several purposes.The master control set that other are any and the array mode between proving installation are all suitable.
In order to guarantee that proving installation well is fixed on master control set, can arrange on proving installation and master control set proving installation is fixed to buckle structure on master control set.Described buckle structure can be fixed form, buckle snap close or the magnetic patch snap close of screw thread snap close (for example bolt and nut, screw and threaded hole).The structure of described magnetic patch snap close to shown in Figure 13, comprises at least three magnetic patch, the first magnetic patch 151, the second magnetic patch 152 and the 3rd magnetic patch 153 as Figure 10.The first magnetic patch 151 designs are on first device, and the second magnetic patch 152 and the 3rd magnetic patch 153 designs are on the second device.The magnetic of two faces that the first magnetic patch 151 is relative with the second magnetic patch 152 different (being respectively the S utmost point and the N utmost point), the Magnetic Phase of two faces that the second magnetic patch 152 is relative with the 3rd magnet 153 is with (be all the S utmost point or be all the N utmost point).The first magnetic patch 151, the second magnetic patch 152 and the 3rd magnetic patch 153 are roughly overlapping perpendicular to the projection on the direction of its opposite face.If with two mutual snap closes of device when living, to push to the second device of the second magnetic patch 152 close with the first device of the first magnetic patch 151, first device finally is in the same place by magnetic-adsorption with the second device, and at this moment, the 3rd magnetic patch 153 is away from the second magnetic patch 152.If two devices are separated from each other, it is close that push the 3rd magnetic patch 153 to second magnetic patch 152 this moment, utilize the mutual repulsive force between the 3rd magnetic patch 153 and the second magnetic patch 152 and the first magnetic patch 151, weakened the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 153, thereby first device and the second device are separated from each other.
Biochemical Analyzer described in the utility model such as Figure 10 are to embodiment shown in Figure 11, and the first magnetic patch 151 designs are on the backboard 126 of proving installation 100.The second magnetic patch 152 is entrenched in the bonnet lock hole 22 of master control set 10.Be designed with two bracing frames 154 on the master control set bonnet, support frame as described above 154 designs respectively the both sides at bonnet lock hole.The 3rd magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.The magnetic of two faces that the first magnetic patch 151 is relative with the second magnetic patch 152 different (being respectively the S utmost point and the N utmost point), the Magnetic Phase of two faces that the second magnetic patch 152 is relative with the 3rd magnetic patch 153 is with (be all the S utmost point or be all the N utmost point).Shown in Figure 10 is the interior state of storage chamber 15 that proving installation 100 is pushed into master control set 10, at this moment, there is a natural attraction between the sexes because of magnet for the first magnetic patch 151 and the second magnetic patch 152, and this magnetic attraction makes proving installation be inhaled on master control set firmly, and can not skid off from master control set.As shown in figure 11, when needs are extracted proving installation 100 out, the 3rd magnetic patch 153 is pushed away to the second magnetic patch direction, because the polarity of two faces that the second magnetic patch 152 is relative with the 3rd magnetic patch 153 is identical, and the polarity of the face that the 3rd magnetic patch 153 is relative with the first magnetic patch 151 is also identical, according to the principle of the two like magnetic poles repel each other of magnet, the 3rd 153 pairs of magnetic patch the first magnetic patch and the second magnetic patch have a repulsive interaction, have weakened the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 152.Close along with the 3rd magnetic patch 153, this repulsive force can basic neutralisation the first magnetic patch 151 and the second magnetic patch 152 between magnetic attraction.Thereby proving installation 100 just can be extracted out from the storage chamber of master control set at an easy rate.
Figure 12 is the another kind of embodiment of magnetic block lock catch structure, and the 3rd magnetic patch 153 can slide on slide bar 156 by slide bar button 157.Figure 13 is the another kind of embodiment of magnetic block lock catch structure, and the 3rd magnetic patch 153 is conflicted mutually by snak link 159 and spring 158, and spring has the state that is compressed and unfold by the 3rd magnetic patch.
Between master control set and proving installation, testing process as shown in figure 14.Workflow is: opening power at first, Biochemical Analyzer is started shooting and is entered the startup self-detection program, after startup self-detection finishes, enters preheating program, when the probe temperature of Biochemical Analyzer meets predefined temperature range, detector is in the wait test mode, and the operator selects the proving installation that need to test, after putting into the test paper bar, analyser starts test, test outputs test result after finishing, and takes out the test paper bar.Again put into new test paper bar if also will carry out the detection of next sample, the mensuration of a beginning new round.If all samples has all been tested and has been completed, shutdown.
Be below another embodiment of the present utility model.
As shown in Figure 15 to 21, biochemical analysis tester 1a comprises main control unit 50a and at least two test cell 100a of being arranged in casing 2a.Corresponding to each test cell 100a, test cell door 3a is installed on casing.
Main control unit 50a is connected the modes such as data line, electric wire with total power switch, the data input/output control system of biochemical analysis tester 1a respectively and is connected with test cell 100a.The data I/O comprises liquid crystal display 4a, USB interface, data line interface and printer etc.
Test cell 100a comprises sample conveying device 110a and testing light source device 111a.
The sample conveying device 110a of test cell 100a comprises that carrying detects the pallet 114a of test paper, and a heat transfer plate 115a is arranged below pallet, by this heat transfer plate, the heat that heating arrangement 116a produces is delivered to surveyed area.Described heating arrangement 116a can be selected from the electric elements such as power resistor plate.Placed a lower lock block thermal insulation board 117a below temperature-adjusting heating device 116a, the heat that produces on heating arrangement has been intercepted at this, no longer transmitted toward other positions.Electro-motor 118a is fixed on electro-motor fixed head 119a.When electro-motor is opened, promote plate nut and move up and down.Sample conveying device 110a will detect test bar by pallet 114a and deliver to predefined detection position, preferably control pallet 114a by optical coupled switch 121a and arrive predefined detection position.Described optical coupled switch 121a has lightening hole 122a, and described pallet 114a has lower limb 123a and is positioned at described lightening hole 122a top.Described lower limb 123a has the lightening hole of blocking 122a and leaves two positions of lightening hole 122a with respect to lightening hole 122a.Be positioned at the lightening hole 122a top of optical coupled switch 121a as the lower limb 123a of pallet 114a, light path is unimpeded, and this moment, the electro-motor power supply kept power supply state always.Under electro-motor 118a rotated, pallet 114a continued to move upward.After pallet 114a continued to rise and touches detection light source device 112a, 112a maintained static due to the detection light source device, and pallet just can not continue to move ahead, and light supply apparatus can produce pallet 114a and continue downward pressure.But optical coupled switch also moves upward continuing under the drive of electro-motor, until the lower limb 123a of pallet 114a has stopped the lightening hole 122a of optical coupled switch 121a.After lightening hole was blocked, light path just was cut off, thereby closed the power supply of electro-motor.At this moment, detect test paper and arrived the detection position, the biochemical analysis tester is opened sample detection light supply apparatus 112a and is carried out the analysis of sample.
Described testing light source device 111a comprises testing light source 112a and upper holder block 113a.Be equipped with for described detection test paper is produced pressure described upper holder block 113a and described lower extrusion plate 117a.In a specific embodiment of the present utility model, pressure is generally 1kgf/cm 2-3kgf/cm 2, that better is 2 kgf/cm 2Described light supply apparatus has the effect of two aspects at least: 1) light is imported into to the conversion zone that detects test paper, and receive the reflected light of reaction zone.2) test zone to pallet transmits light, and receives reflected light information, and reflected light information is offered system, whether has been placed on test paper carrier bench in order to judgement detection test paper first-class to be tested.
Also be provided with the magnetic induction start device of biochemical analysis tester open detection in test cell.The magnetic induction signal that magnetic induction start device produces is connected on main control unit.In one embodiment, magnetic induction start device comprises the magnetic patch 11a on the cell gate that is arranged on the magnetic induction switch 10a in test cell and is arranged on test cell, and its material is selected from magnet steel, and magnet is worked as.When cell gate cuts out, magnetic induction switch 10a senses the field signal of magnetic patch on cell gate, and after field signal was delivered to main control unit, main control unit was judged the particular location of cell gate, for example whether cell gate closed or open, thus by main control unit to whether start detection judges.
On the other hand, the material of biochemical analysis tester casing can chosen from Fe or steel etc. can produce with magnetic patch the material of absorption affinity, an iron block etc. perhaps is installed in test cell.When the test cell door is closed, be subjected to the magneticaction of contact point magnet, the magnetic patch that is arranged on cell gate can be pull-in on cell gate on the casing of main frame firmly, thereby realizes the sealed of cell gate.Therefore the biochemical analysis tester does not need to acquire other unit lock locking device again.
The modes such as magnetic patch is fixed with viscose or screw is fixing are fixed on cell gate.Magnetic patch can be closed in cell gate or be placed on outside cell gate.
Test paper application of sample operator's console 5a also is housed on the casing 2a of analysis tester.When adding sample, test paper can temporarily leave on described test paper operator's console 5a.Operator's console is a draw-in groove type structure in one embodiment, and described operator's console is comprised of upper plate 6a and lower plate 7a, and leaves gap 8a between upper plate and lower plate, and described gap spacing is just in time the thickness of test paper or larger than test paper thickness a little.The fore-end of test paper is blocked in the gap of operator's console, and the application of sample position of test paper and the place of being affectedly bashful are all in the outside of operator's console, and the bottom surface of test paper being affectedly bashful the position does not touch the experiment desktop.Very convenient like this operator's application of sample and pick up test paper.When application of sample, at first the operator is stuck in test paper in the draw-in groove of operator's console, then carries out application of sample.Because the part of being affectedly bashful of test paper is soared aloft, after adding sample, the operator can pick up the test paper that is added with sample easily, this test paper is put on the detection platform of test cell.Described test paper operator's console can be arranged on below, side or the top of test cell door.
In embodiment as shown in figure 20, described biochemical analysis tester comprises independently test cell of a main control unit and three.Main control unit is connected with power supply, printer, display system, USB interface, Parameters Input Unit etc.Main control unit also is connected with three test cells respectively.Test cell is independently completed detection separately, and test result is transferred to main control unit, by main control unit output detections result.Test cell comprises baffled photometer, mechanical driving device and temperature control equipment etc.
Biochemical analysis method of testing as described in Figure 21 comprises:
1) open the Biochemical Analyzer tester, and test parameter is set, described biochemical analysis tester comprises main control unit and at least two separate test cells, main control unit interconnects with analyser power control switch, data output device, input control system and test cell respectively, and each test cell comprises sample conveying device 110a and testing light source device 111a.
The test paper that 2) will add sample is put into one of them test cell.
3) the biochemical analysis tester judges whether detection zone has test paper to exist, if do not have, the biochemical analysis tester provides the information that reapposes test paper.
4) the biochemical analysis tester judges whether the test cell door closes, if do not have, the biochemical analysis tester provides the information of closing unit door.
5) when test paper Already in detection zone and cell gate closed these two groups of information when all possessing, the biochemical analysis tester begins start detection and output detections result.
In one embodiment, the biochemical analysis tester also can just detect the start time and whether surpass the time that presets and judge after receiving test paper Already in detection zone and cell gate have been closed these two groups of information.If overtime, the biochemical analysis tester provides the information of again changing test paper.If not overtime, the biochemical analysis tester begins start detection and output detections result.
In test process, each test cell independently detects, and does not interfere with each other, thereby has improved test speed, can detect more sample at one time.
The biochemical analysis tester utilizes the light supply apparatus of test cell to come the interpretation detection zone whether to place test paper.Testing light source sends test light, and judges by the reflected light information of pallet detection zone whether detection zone has test paper to exist.If no, the biochemical analysis tester provides the information that reapposes test paper.
The biochemical analysis tester judges by the magnetic induction signal whether the test cell door is shut.When cell gate cuts out, magnetic induction switch 10a senses the field signal of magnetic patch on cell gate, and after field signal was delivered to main control unit, main control unit was judged the particular location of cell gate, for example whether closed or open, thus by main control unit to whether start detection judges.
The detection of a series of physiological and biochemical indexs such as Biochemical Analyzer described in the utility model and method of testing can be used for glucose, cholesterol, high density fat is sour, low density fat is sour, triglyceride, uric acid, cholerythrin, total protein, haemoglobin, ketoboidies.

Claims (9)

1. biochemical analysis tester, the test cell that comprises casing, fixes with casing, the test cell door corresponding with test cell, wherein test cell includes temperature control equipment, mechanical motion control device and detects light path device, it is characterized in that, test cell and the test cell door corresponding with it are provided with by closing the test cell door and automatically start the magnetic induction start device that test cell carries out work.
2. biochemical analysis tester according to claim 1, is characterized in that, magnetic induction start device comprises the magnetic patch that is arranged on the test cell door and is arranged on the interior magnetic induction switch of test cell.
3. biochemical analysis tester according to claim 1, is characterized in that, described magnetic patch material is magnet steel.
4. biochemical analysis tester according to claim 1, is characterized in that, the mode that described magnetic patch is fixed with viscose or screw state is fixed is fixed on cell gate.
5. biochemical analysis tester according to claim 1, is characterized in that, magnetic patch is closed in cell gate or is placed on outside cell gate.
6. biochemical analysis tester according to claim 1, is characterized in that, described sample conveying device comprises that carrying detects the pallet of test paper, has a heat transfer plate below pallet.
7. biochemical analysis tester according to claim 6, is characterized in that, this biochemical analysis tester also comprises for the optical coupled switch of controlling the predefined detection position of pallet arrival.
8. biochemical analysis tester according to claim 6, is characterized in that, it also comprises heating arrangement, and described heating arrangement is selected from the power resistor plate.
9. biochemical analysis tester according to claim 1, is characterized in that, this biochemical analysis tester comprises at least two test cells, and each test cell is corresponding to a described test cell door and a described magnetic induction start device.
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CN2011102817102A CN102374969A (en) 2011-09-21 2011-09-21 Magnetic block lock catch structure, using method thereof and application thereof to biochemical analyzer
CN201210285607 2012-08-13
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