CN112578139B - Sample testing method, sample analyzer and storage medium - Google Patents
Sample testing method, sample analyzer and storage medium Download PDFInfo
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- CN112578139B CN112578139B CN201910943666.3A CN201910943666A CN112578139B CN 112578139 B CN112578139 B CN 112578139B CN 201910943666 A CN201910943666 A CN 201910943666A CN 112578139 B CN112578139 B CN 112578139B
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
Abstract
The embodiment of the invention discloses a sample testing method, a sample analyzer and a storage medium, wherein the method comprises the following steps: under the condition that sample injection of a sample rack is detected, when judging that the test waiting time of the sample analyzer exceeds the preset duration, switching the sample analyzer from a first state to a second state; the first state is a state in which sample detection can be started, and the second state is a state in which sample detection cannot be started; under the condition that the sample analyzer is in the second state, judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample frame is detected to reach the preset position of the sample analyzer; and if the sample analyzer meets the condition of immediately exiting the second state, and performing sample detection on the sample to be detected on the sample rack.
Description
Technical Field
The present invention relates to the field of in vitro diagnosis, and in particular, to a sample testing method, a sample analyzer, and a storage medium.
Background
Sample analyzers, such as biochemical analyzers or immune analyzers, are typically responsible for testing samples on sample racks, and in particular, users click a start button of a software interface, or an operation button of an SDM module activates the sample analyzer, and a dispatch module transports the sample rack with the samples placed therein to the sample analyzer for testing the samples on the sample rack with the sample analyzer. However, when there are multiple sample analyzers on the assembly line, the sample frames need to be transported from outside the system to the front end of the corresponding analyzer, and the sample frames need to be transported through the fixed transport track, and when the sample frames needing to be transported are too many, the subsequent sample frames can be blocked by the front sample frames, so that the subsequent sample frames can not be transported to the front end of the corresponding analyzer in time, at this time, in order to reduce the loss of the light source components of the sample analyzer and the consumption of consumables (such as cleaning liquid or substrate), the sample analyzer can enter the flow of stopping the sample test, when the subsequent sample frames are transported to the front end of the sample analyzer, the user is required to start the sample analyzer again, otherwise, the sample frames are transported to the recovery area, and the sample frames are detected from the recovery area to perform the sample test process when the sample analyzer is started next time. The existing manual starting sample analyzer can cause that sample test cannot be performed in time, and further causes the problems of low sample test intelligence and complex sample test flow.
Disclosure of Invention
In order to solve the above technical problems, it is desirable to provide a sample testing method, a sample analyzer and a storage medium, which can improve the intelligence of the sample test and reduce the complexity of the sample test flow.
The embodiment of the invention provides a sample testing method, which comprises the following steps:
under the condition that sample injection of a sample rack is detected, when judging that the test waiting time of the sample analyzer exceeds the preset duration, switching the sample analyzer from a first state to a second state; the first state is a state capable of starting sample detection, and the second state is a state incapable of starting sample detection;
judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample rack is detected to reach the preset position of the sample analyzer under the condition that the sample analyzer is in the second state;
and if the sample analyzer meets the condition of immediately exiting the second state, and performing sample detection on the sample to be detected on the sample frame.
In the above method, the determining whether the sample analyzer satisfies a condition of immediately exiting the second state includes:
Judging whether the sample analyzer currently executes a task flow;
if the task flow is executed and the task flow cannot be stopped immediately, the condition of exiting the second state immediately is not satisfied; if the task flow is executed but can be stopped immediately, the condition of exiting the second state immediately is satisfied;
if the task flow is not executed, the condition of immediately exiting the second state is satisfied.
In the above method, after the determining whether the sample analyzer currently executes the task flow, the method further includes:
if the task flow is executed and the task flow cannot be stopped immediately, the current task flow is finished first;
and the second state is exited until the sample analyzer executes the current task flow, and a sample testing process of the sample to be tested is started.
In the above method, after the sample analyzer is switched from the first state to the second state, the method further includes:
in the second state, the sample analyzer enters a sleep state or performs an instrument maintenance procedure.
In the above method, if the sample analyzer satisfies a condition of immediately exiting the second state, exiting the second state includes:
When the current task flow is a first task flow in the maintenance flow of the execution instrument, characterizing that the sample analyzer meets the condition of exiting the second state immediately, wherein the first task flow is a task flow of a type of interrupt immediately in the maintenance flow;
ending the current task flow and exiting the second state.
In the above method, the sample analyzer front end is provided with a sample identification component, and when the sample rack is detected to reach the preset position of the sample analyzer, determining whether the sample analyzer meets the condition of immediately exiting the second state includes:
detecting that the sample rack reaches the preset position when the sample rack is detected by the sample recognition component, wherein the sample recognition component comprises a sensor and/or a sample scanning component;
acquiring sample information of the sample to be tested from the sample rack to perform a sample test based on the sample information;
and acquiring the current task flow of the sample analyzer, and judging whether the sample analyzer meets the condition of immediately exiting the second state according to the current task flow.
In the above method, the first state is an idle state, and the second state is a sleep state.
An embodiment of the present invention provides a sample analysis system including:
at least one sample analyzer for performing a sample detection analysis;
the sample conveying rail is used for conveying a sample rack carrying a sample to be tested to the target sample analyzer for sample analysis;
the sample injection detection device is used for detecting whether a sample frame injects sample to the sample conveying track;
the control device is used for switching the target sample analyzer from the first state to the second state when judging that the test waiting time of the target sample analyzer exceeds the preset duration under the condition of detecting sample injection of the sample rack; the first state is a state capable of starting sample detection, and the second state is a state incapable of starting sample detection; judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample rack is detected to reach the preset position of the sample analyzer under the condition that the sample analyzer is in the second state; if the sample analyzer meets the condition of immediately exiting the second state, exiting the second state; and after the target sample analyzer exits the second state, the target sample analyzer is used for executing sample detection on the sample to be detected on the sample rack.
In the above sample analysis system, the control device is further configured to determine whether the sample analyzer currently executes a task flow; if the task flow is executed and the task flow cannot be stopped immediately, the condition of exiting the second state immediately is not satisfied; if the task flow is executed but can be stopped immediately, the condition of exiting the second state immediately is satisfied; if the task flow is not executed, the condition of immediately exiting the second state is satisfied.
In the above sample analysis system, the control device is further configured to complete the current task flow if the task flow is executed and the task flow cannot be stopped immediately; and the second state is exited until the sample analyzer executes the current task flow, and a sample testing process of the sample to be tested is started.
In the above sample analysis system, the control device is further configured to, in the second state, enter a sleep state or execute an instrument maintenance procedure.
In the above sample analysis system, the control device is further configured to characterize that the sample analyzer satisfies a condition of immediately exiting the second state when the current task flow is a first task flow in the maintenance flow of the execution instrument, where the first task flow is a task flow of a type of immediately interrupting in the maintenance flow; ending the current task flow and exiting the second state.
In the sample analysis system, a sample identification member is provided at the front end of the sample analyzer,
the sample identifying component is used for detecting that the sample rack reaches the preset position when the sample rack is detected by the sample identifying component, and the sample identifying component comprises a sensor and/or a sample scanning component;
the control device is further used for acquiring sample information of the sample to be tested from the sample rack so as to perform a sample testing process based on the sample information; and acquiring a current task flow of the sample analyzer, and judging whether the sample analyzer meets the condition of immediately exiting the second state according to the current task flow.
In the sample analysis system, the first state is an idle state, and the second state is a sleep state.
An embodiment of the present invention provides a sample testing device, which is applied to a sample analysis system, and includes: a processor, a memory and a computer program stored on the memory and executable on the processor, which when executed by the processor implements a method as claimed in any one of the preceding claims.
Embodiments of the present invention provide a computer readable storage medium having stored thereon a computer program for use in a sample analysis system, which when executed by a processor, implements a method as claimed in any of the preceding claims.
The embodiment of the invention provides a sample testing method, a sample analyzer and a storage medium, wherein the method can comprise the following steps: under the condition that sample injection of a sample rack is detected, when judging that the test waiting time of the sample analyzer exceeds the preset duration, switching the sample analyzer from a first state to a second state; the first state is a state in which sample detection can be started, and the second state is a state in which sample detection cannot be started; under the condition that the sample analyzer is in the second state, judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample frame is detected to reach the preset position of the sample analyzer; if the sample analyzer meets the condition of immediately exiting the second state, and carrying out sample detection on the sample to be detected on the sample rack, adopting the implementation scheme of the method, when the sample analysis system is in the second state which can not start sample detection and the sample analysis system detects that the sample rack reaches the preset position of the sample analyzer under the condition of detecting sample rack sample introduction, the sample analysis system can automatically judge whether the condition of immediately exiting the second state is met, and when the sample analyzer meets the condition of immediately exiting the second state, and automatically starting the sample analyzer to execute the process of sample test, thereby improving the intelligence of sample test and reducing the complexity of a sample test flow.
Drawings
FIG. 1 is a schematic diagram of a sample analysis system according to an embodiment of the present invention;
fig. 2 is a schematic flow chart of a schematic sample testing method for a top view structure of a sample analyzer according to an embodiment of the present invention;
FIG. 3 is a flowchart of a sample testing method according to an embodiment of the present invention;
FIG. 4 is a schematic flow chart of an exemplary sample analyzer for self-starting according to an embodiment of the present invention;
FIG. 5 is a schematic flow chart of sample testing by an exemplary sample analysis system according to an embodiment of the present invention;
fig. 6 is a schematic diagram of a sample analysis system according to an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
The numbering of the components itself, e.g. "first", "second", etc., is used herein merely to distinguish between the described objects and does not have any sequential or technical meaning. The term "coupled" as used herein includes both direct and indirect coupling (coupling), unless otherwise indicated. In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element in question must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
In the present invention, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.
Referring to fig. 1, an embodiment of the present invention provides a sample analyzer. The sample analysis system includes: at least one sample analyzer for performing a sample detection analysis; the sample conveying rail is used for conveying a sample rack carrying a sample to be tested to the target sample analyzer for sample analysis; the sample injection detection device is used for detecting whether a sample frame injects sample to the sample conveying track; the control device is used for switching the target sample analyzer from the first state to the second state when judging that the test waiting time of the target sample analyzer exceeds the preset duration under the condition of detecting sample injection of the sample rack; the first state is a state capable of starting sample detection, and the second state is a state incapable of starting sample detection; judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample rack is detected to reach the preset position of the sample analyzer under the condition that the sample analyzer is in the second state; if the sample analyzer meets the condition of immediately exiting the second state, exiting the second state; and after the target sample analyzer exits the second state, the target sample analyzer is used for executing sample detection on the sample to be detected on the sample rack.
Optionally, the control device is further configured to determine whether the sample analyzer currently executes a task flow; if the task flow is executed and the task flow cannot be stopped immediately, the condition of exiting the second state immediately is not satisfied; if the task flow is executed but can be stopped immediately, the condition of exiting the second state immediately is satisfied; if the task flow is not executed, the condition of immediately exiting the second state is satisfied.
Optionally, the control device is further configured to complete the current task flow if the task flow is executed and the task flow cannot be stopped immediately; and the second state is exited until the sample analyzer executes the current task flow, and a sample testing process of the sample to be tested is started.
Optionally, the control device is further configured to, in the second state, enter a sleep state or perform an instrument maintenance procedure.
Optionally, when the current task flow is a first task flow in the maintenance flow of the execution instrument, the control device is further configured to characterize that the sample analyzer meets a condition of exiting the second state immediately, where the first task flow is a task flow of an immediate interrupt type in the maintenance flow; ending the current task flow and exiting the second state.
Optionally, a sample identification component is arranged at the front end of the sample analyzer,
the sample identifying component is used for detecting that the sample rack reaches the preset position when the sample rack is detected by the sample identifying component, and the sample identifying component comprises a sensor and/or a sample scanning component;
the control device is further used for acquiring sample information of the sample to be tested from the sample rack so as to perform a sample testing process based on the sample information; and acquiring a current task flow of the sample analyzer, and judging whether the sample analyzer meets the condition of immediately exiting the second state according to the current task flow.
Optionally, the first state is an idle state, and the second state is a sleep state.
Specifically, as shown in fig. 2, in the present invention, a sample analyzer, particularly a chemiluminescent immunoassay analyzer, may include a sample reagent loading device 1, an incubation photometry device 2, a dispensing device 3, a magnetic separation washing device 4, a reaction container gripping device 5, a mixing device 6, a waste liquid discharge device 7, a reaction container loading device 8, a control device (not shown), and the like. The sample reagent loading device 1 is used for loading a sample and a reagent. Specifically, the sample reagent loading device 1 is capable of storing a plurality of samples. The sample reagent loading device 1 can also load various reagents required in sample detection, so that the required reagents can be conveniently selected, and the reagent sucking efficiency is improved. The dispensing device 3 comprises a sample and/or reagent needle (not shown) for aspirating and aspirating samples and reagents to effect transfer of the samples and reagents into the reaction vessel. The mixing device 6 is used for supporting the reaction vessel. It will be appreciated that the empty reaction vessel is transferred to the mixing device, the sample and reagent are transferred to the reaction vessel by the dispensing device 3, and the reaction vessel is transferred to the incubation light measuring device 2 after the sample and reagent are mixed uniformly by the mixing device 6. The incubation photometry device 2 is used for incubation and luminescence detection, and the magnetic separation cleaning device 4 is used for separation cleaning. After the reaction container is transferred to the incubation photometry device 2, the incubation photometry device 2 can incubate the sample and the reagent in the reaction container, the incubated reaction container is transferred to the magnetic separation cleaning device 4 for separation cleaning, and the cleaned reaction container is transferred back to the incubation photometry device 2 for luminescence detection so as to obtain the corresponding parameters of the sample. The reaction vessel gripping device 5 is used for transferring the reaction vessel between the mixing device 6, the incubation photometry device 2 and the magnetic separation washing device 4. The waste liquid discharging device 7 is used for discharging waste liquid in the reaction vessel after detection, and the waste liquid discharging device 7 can also shade the reaction vessel for luminescence detection in the incubation photometry device 2 while discharging waste liquid. The reaction vessel loading device 8 is used for loading a reaction vessel in which a sample and a reagent react.
As shown in fig. 3, an embodiment of the present invention provides a sample testing method applied to a sample analysis system, particularly according to the present invention, including at least one sample analyzer, which may be a biological analyzer or an immunoassay analyzer, the method comprising:
s101, under the condition that sample injection of a sample rack is detected, when judging that the test waiting time of the sample analyzer exceeds a preset duration, switching the sample analyzer from a first state to a second state. The first state is a state in which sample detection can be started, and the second state is a state in which sample detection cannot be started.
The sample testing method provided by the embodiment of the invention is suitable for a scene that the sample analyzer detects sample injection of the sample rack in a non-testing state.
In an embodiment of the invention, the sample analysis system further comprises a sample conveying track and a sample detection device, wherein the sample detection state is used for detecting whether a sample rack samples to the sample conveying track, and the sample conveying track is used for conveying the sample rack carrying the sample to be detected to a target sample analyzer for sample analysis.
In an embodiment, the sample analysis system detects whether the sample rack is sampled by using the sample detection device, and when the sample analysis system detects that the sample rack is sampled by using the sample detection device, the sample analysis system obtains the test waiting time of the sample analyzer, wherein the test waiting time is a time period between the ending time of the sample test on the sample analyzer and the current time of detecting the sample rack sample.
When the sample analyzer completes one sample test operation, the sample analyzer is switched from a test state to an idle state, waits for the next round of sample injection of the sample rack in the idle state, and executes the next round of sample test task; when a plurality of analyzers exist on the assembly line, the sample analysis system conveys sample frames to the front ends of the corresponding sample analyzers through the sample conveying tracks, the subsequent sample frames can be blocked by the front sample frames when the number of the sample frames to be conveyed is large, and the sample frames can not be conveyed to the front ends of the corresponding sample analyzers temporarily, at the moment, the sample analyzers are always in an idle state, and the mechanical parts of the sample analyzers are lost and the consumable materials are consumed.
In order to reduce the loss of mechanical parts and consumption of consumable materials of the sample analyzer, a preset duration is preset in the sample analysis system, when the test waiting time of the sample analyzer reaches the preset duration, the sample analysis system is characterized in that the sample analyzer does not execute a sample test task for a long time, at the moment, the sample analysis system switches the sample analyzer from an idle state to a dormant state, and at the moment, the sample analyzer can enter the dormant state or execute an instrument maintenance flow; when the test waiting time of the sample analyzer does not reach the preset time, the sample analyzer is still in an idle state and waits for the next round of sample rack sample injection.
The first state is an idle state, namely a state in which the sample analyzer can start sample detection; the second state is a dormant state, i.e., a state in which the sample analyzer cannot initiate sample detection.
For example, in the second state, the biochemical analyzer may enter a sleep state, an awake state, an incubation state, etc., and specifically, the second state may be selected or added according to practical situations, which is not limited in the embodiments of the present invention.
For the immunity analyzer, in the second state, the immunity analyzer may enter an idle state, an incubation state, an automatic mixing state, an automatic condensed water discharging state, an automatic effect detection state, etc., specifically, the immunity analyzer is selected or added according to the actual situation, and the embodiment of the invention is not limited specifically.
S102, under the condition that the sample analyzer is in the second state, judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample frame is detected to reach the preset position of the sample analyzer.
When the sample analyzer is switched from the first state to the second state, the sample analyzer enters the second state, and when the sample rack is detected to reach the preset position of the sample analyzer under the condition of being in the second state, whether the sample analyzer meets the condition of immediately exiting the second state is judged.
In the embodiment of the invention, the front end of the sample analyzer is provided with the sample identification component, wherein the sample identification component comprises a sensor, a sample scanning component and the like, and the sample identification component is specifically selected according to practical conditions, and the embodiment of the invention is not particularly limited. When the sample analysis system detects the sample rack by using the sample recognition component, the sample analysis system detects that the sample rack reaches a preset position; at this time, on the one hand, the sample analysis system obtains the sample information of the sample to be tested from the sample rack, in order to carry on the course of the sample test based on the sample information; on the other hand, the current task flow of the sample analysis system is obtained, and whether the sample analyzer meets the condition of immediately exiting the second state is judged according to the current task flow.
In the embodiment of the present invention, the current task flow executable by the sample analyzer in the second state includes two types, respectively: the specific process that the sample analysis system judges whether the sample analyzer meets the condition of immediately exiting the second state according to the current task flow is as follows: the sample analysis system judges whether the sample analyzer currently executes a task flow; if the sample analyzer executes the task flow and the task flow cannot be stopped immediately, the condition of exiting the second state immediately is not satisfied; if the sample analyzer executes the task flow, but the task flow can be stopped immediately, the condition of exiting the second state immediately is satisfied; if the sample analyzer does not execute the task flow, the condition for immediately exiting the second state is satisfied.
In one possible embodiment, for the biochemical analyzer, when the biochemical analyzer is in an idle state, the biochemical analyzer does not perform a task flow, at which time the biochemical analyzer satisfies a condition of immediately exiting the second state; when the biochemical analyzer is in a dormant state or an awake state, the task flow executed by the biochemical analyzer can be immediately interrupted, and at the moment, the biochemical analyzer meets the condition of immediately exiting the second state; when the biochemical analyzer is in an incubation state, the biochemical analyzer performs an incubation task, and the biochemical analyzer needs to control the temperature of the instrument to reach the incubation temperature and enable the blood sample and the reagent to fully react, so that the incubation state cannot be immediately stopped, and at the moment, the biochemical analyzer does not meet the condition of immediately exiting the second state.
In another possible embodiment, for the immunoassay analyzer, when the immunoassay analyzer is in the idle state, the immunoassay analyzer does not perform the task flow, at which time the immunoassay analyzer satisfies the condition of immediately exiting the second state; when the immunoassay analyzer is in an incubation state, the immunoassay analyzer does not meet the condition of immediately exiting the second state; when the immune analyzer is in an automatic maintenance state such as automatic mixing, automatic condensate water discharging and automatic effect detection, the immune analyzer executes task flows such as automatic mixing, automatic condensate water discharging and automatic effect detection, and the automatic mixing task flows, the automatic condensate water discharging task flows and the automatic effect detection task flows can be stopped immediately, and at the moment, the immune analyzer meets the condition of exiting the second state immediately.
S103, if the sample analyzer meets the condition of immediately exiting the second state, and performing sample detection on the sample to be detected on the sample frame.
In one possible embodiment, when the sample analysis system determines that the current task flow is a first task flow in the maintenance flow of the execution instrument, the sample analyzer is characterized as meeting a condition of immediately exiting the second state, wherein the first task flow is a task flow of an immediate interrupt type in the maintenance flow; at this time, the sample analyzer ends the current task flow and exits the second state.
Optionally, the first task flow may include an automatic blending task flow, an automatic condensate water draining task flow, and an automatic effect detecting task flow, which are specifically selected according to actual situations, and the embodiment of the present invention is not limited specifically.
Further, if the sample analysis system judges that the sample analyzer currently executes the task flow and the task flow cannot be stopped immediately, the sample analysis system judges that the sample analyzer does not meet the condition of exiting the second state immediately, and the sample analyzer completes the current task flow first; and when the sample analyzer executes the current task flow, the sample analyzer meets the condition of immediately exiting the second state, the sample analyzer exits the second state, and a sample testing process of the sample to be tested is started.
Exemplary, fig. 4 is a flowchart of self-starting in a scenario in which the sample analyzer is in a test-suspension state:
1. the sample analysis system judges whether the sample rack is transported to a front end track of the sample analyzer;
2. when the sample analysis system judges that the sample rack is transported to the front end track of the sample analyzer, the sample analyzer judges whether a sample adding task is acquired or not;
3. when the sample analyzer judges that a sample adding task is acquired, the sample analysis system starts the sample analyzer;
4. when the sample analysis system starts the sample analyzer successfully, the sample analyzer starts to perform sample testing;
5. when the sample analysis system fails to start the sample analyzer, stopping running the sample analyzer, and transporting the sample rack back to the recovery area;
6. when the sample analysis system temporarily fails to start the sample analyzer, step 3 is performed.
In practical application, when the sample analysis system includes two biochemical/immunological analyzers of M1 and M2 and a scheduling module, the specific flow of sample detection performed by the sample analyzer is as follows:
1. the medical staff starts the sample analysis system, and at the moment, the scheduling module, M1 and M2 are started at the same time;
2. the scheduling module detects the sample and conveys the sample to M1, at the moment, M2 has no sample processing, and the idle state is restored;
3. When the consumable in M1 is insufficient, waiting for consumable replenishment, and after an idle state for a certain time, entering a dormant state by M2;
4. after the consumable in M1 is supplemented, carrying out a sample test process in M1, and at the moment, transporting another sample to M2 by the scheduling module;
5. m2 exits sleep mode and self-starts to complete the sample testing process in M2.
It can be understood that under the condition that the sample rack sample injection is detected, when the sample analysis system is in the second state in which the sample detection cannot be started and the sample analysis system detects that the sample rack reaches the preset position of the sample analyzer, the sample analysis system can automatically judge whether the condition of immediately exiting the second state is met or not, and when the sample analyzer meets the condition of immediately exiting the second state, the second state is exited, and the sample analyzer is automatically started to execute the process of sample test, so that the intelligence of the sample test is improved, and the complexity of a sample test flow is reduced.
As shown in fig. 6, an embodiment of the present invention provides a sample analysis system applied to a sample analyzer, particularly a biochemical analyzer or a chemiluminescent immunoassay analyzer, particularly according to the present invention, the sample analysis system 1000 may include:
A memory 1004 for storing instructions and data;
the processor 1002 executes the instructions to: under the condition that sample injection of a sample rack is detected, when judging that the test waiting time of the sample analyzer exceeds the preset duration, switching the sample analyzer from a first state to a second state; the first state is a state capable of starting sample detection, and the second state is a state incapable of starting sample detection; judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample rack is detected to reach the preset position of the sample analyzer under the condition that the sample analyzer is in the second state; and if the sample analyzer meets the condition of immediately exiting the second state, and performing sample detection on the sample to be detected on the sample frame.
The processor 1002 of the sample analysis system 1000 is configured to control the at least one sample analyzer, the sample conveying rail, the sample detection device, and the control device to implement corresponding method steps, where the processor 1002 may be at least one of an ASIC (application specific integrated circuit), a DSP (DSP, digital Signal Processor), a DSP (DSPD, digital Signal Processing Device), a programmable logic device (PLD, programmable Logic Device), a field programmable gate array (FPGA, field Programmable Gate Array), a CPU (CPU, central Processing Unit), a controller, a microcontroller, and a microprocessor. It will be appreciated that the electronics for implementing the functions of the processor 1002 may be other for different devices, and embodiments of the present invention are not specifically limited.
The memory 1004 of the sample analysis system 1000 is configured to store executable program code including computer operating instructions, and the memory 1004 may comprise high speed RAM memory and may also comprise non-volatile memory, such as at least one disk memory. In practical applications, the Memory 1004 may be a volatile Memory (RAM) such as Random-Access Memory; or a nonvolatile Memory (non-volatile Memory), such as a Read-Only Memory (ROM), a flash Memory (flash Memory), a Hard Disk (HDD) or a Solid State Drive (SSD); or a combination of the above types of memory and provides instructions and data to the processor 1002.
The sample analysis system 1000 may also include a communication bus 1006 for connecting the processor 1002 and the memory 1004 to enable intercommunication among these devices and/or for data transmission with external network elements.
In addition, each functional module in the present embodiment may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit. The integrated units may be implemented in hardware or in software functional modules.
The integrated units, if implemented in the form of software functional modules, may be stored in a computer-readable storage medium, if not sold or used as separate products, and based on such understanding, the technical solution of the present embodiment may be embodied essentially or partly in the form of a software product, which is stored in a storage medium and includes several instructions to cause a computer device (which may be a personal computer, a server, or a network device, etc.) or processor to perform all or part of the steps of the method described in the present embodiment. And the aforementioned storage medium includes: a usb disk, a removable hard disk, a ROM, a RAM, a magnetic disk, or an optical disk, etc.
Embodiments of the present invention provide a computer readable storage medium having stored thereon a computer program for use in a sample analyzer, which when executed by the processor 1002, implements the above-described sample testing method.
It will be appreciated by those skilled in the art that embodiments of the invention may be provided as a method, server, or computer program product. Accordingly, the present invention may take the form of a hardware embodiment, a software embodiment, or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, magnetic disk storage, optical storage, and the like) having computer-usable program code embodied therein.
The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (servers) and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flowchart illustrations and/or block diagrams, and combinations of flows and/or blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
The above-mentioned features can be combined with each other arbitrarily as long as they are meaningful within the scope of the present invention. The advantages and features described for the sample analyzer apply in a corresponding manner to the sample testing method and to the sample testing device.
While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that these specific embodiments are illustrative only. Those skilled in the art can make various changes and modifications to these embodiments without departing from the principles of the present invention, and such changes and modifications fall within the scope of the present invention.
Claims (16)
1. A method of testing a sample, comprising:
when the sample rack is detected to enter a sample conveying track of a sample analysis system and the test waiting time of the sample analyzer exceeds the preset duration, the sample analyzer is switched from a first state to a second state; the sample rack entering the sample conveying track within the preset time period does not reach the preset position of the sample analyzers, the sample conveying track is connected with at least two sample analyzers in the sample analysis system, the first state is a state capable of starting sample detection, the second state is a state incapable of starting sample detection, and the test waiting time is a time period from the ending time of the sample testing on the sample analyzers to the current time of detecting sample rack sample injection;
Judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample rack is detected to reach the preset position of the sample analyzer under the condition that the sample analyzer is in the second state;
and if the sample analyzer meets the condition of immediately exiting the second state, and performing sample detection on the sample to be detected on the sample frame.
2. The method of claim 1, wherein said determining whether the sample analyzer satisfies a condition for immediately exiting the second state comprises:
judging whether the sample analyzer currently executes a task flow;
if the task flow is executed and the task flow cannot be stopped immediately, the condition of exiting the second state immediately is not satisfied; if the task flow is executed but can be stopped immediately, the condition of exiting the second state immediately is satisfied;
if the task flow is not executed, the condition of immediately exiting the second state is satisfied.
3. The method of claim 2, wherein after said determining whether the sample analyzer is currently performing a task flow, the method further comprises:
If the task flow is executed and the task flow cannot be stopped immediately, the current task flow is finished first;
and the second state is exited until the sample analyzer executes the current task flow, and a sample testing process of the sample to be tested is started.
4. The method according to claim 1 or 2, wherein after the sample analyzer is switched from the first state to the second state, the method further comprises:
in the second state, the sample analyzer enters a sleep state or performs an instrument maintenance procedure.
5. The method of claim 4, wherein the exiting the second state if the sample analyzer satisfies a condition to immediately exit the second state comprises:
when the current task flow is a first task flow in the maintenance flow of the execution instrument, characterizing that the sample analyzer meets the condition of immediately exiting the second state, wherein the first task flow is a task flow which can be immediately interrupted in the maintenance flow;
ending the current task flow and exiting the second state.
6. The method according to claim 1, wherein the sample analyzer front end is provided with a sample recognition part, and the determining whether the sample analyzer satisfies the condition of immediately exiting the second state when the sample rack reaches the preset position of the sample analyzer includes:
Detecting that the sample rack reaches the preset position when the sample rack is detected by the sample recognition component, wherein the sample recognition component comprises a sensor and/or a sample scanning component;
acquiring sample information of the sample to be tested from the sample rack so as to perform sample testing based on the sample information;
and acquiring the current state of the sample analyzer, and judging whether the sample analyzer meets the condition of immediately exiting the second state according to the current state of the sample analyzer.
7. The method of claim 1, wherein the first state is an idle state and the second state is a dormant state.
8. A sample analysis system, the sample analysis system comprising:
at least one sample analyzer for performing a sample detection analysis;
the sample conveying rail is used for conveying a sample rack carrying a sample to be tested to the target sample analyzer for sample analysis;
the sample injection detection device is used for detecting whether a sample frame injects sample to the sample conveying track;
the control device is used for switching the target sample analyzer from the first state to the second state when judging that the test waiting time of the target sample analyzer exceeds the preset duration under the condition that the sample rack is detected to enter the sample conveying track of the sample analysis system; the sample rack entering the sample conveying track within the preset time period does not reach the preset position of the sample analyzers, the sample conveying track is connected with at least two sample analyzers in the sample analysis system, the first state is a state capable of starting sample detection, the second state is a state incapable of starting sample detection, and the test waiting time is a time period from the ending time of the sample testing on the sample analyzers to the current time of detecting sample rack sample injection; judging whether the sample analyzer meets the condition of immediately exiting the second state when the sample rack is detected to reach the preset position of the sample analyzer under the condition that the sample analyzer is in the second state; if the sample analyzer meets the condition of immediately exiting the second state, exiting the second state; and after the target sample analyzer exits the second state, the target sample analyzer is used for executing sample detection on the sample to be detected on the sample rack.
9. The sample analysis system of claim 8, wherein the sample analysis system comprises a sample analyzer,
the control device is also used for judging whether the sample analyzer currently executes a task flow; if the task flow is executed and the task flow cannot be stopped immediately, the condition of exiting the second state immediately is not satisfied; if the task flow is executed but can be stopped immediately, the condition of exiting the second state immediately is satisfied; if the task flow is not executed, the condition of immediately exiting the second state is satisfied.
10. The sample analysis system of claim 9, wherein the sample analysis system comprises a sample analyzer,
the control device is also used for completing the current task flow if the task flow is executed and can not be stopped immediately; and the second state is exited until the sample analyzer executes the current task flow, and a sample testing process of the sample to be tested is started.
11. The sample analysis system according to claim 8 or 9, wherein,
the control device is further configured to, in the second state, enter a sleep state or perform an instrument maintenance procedure.
12. The sample analysis system of claim 11, wherein the sample analysis system comprises a sample analyzer,
The control device is further configured to characterize that the sample analyzer satisfies a condition of immediately exiting the second state when the current task flow is a first task flow in the maintenance flow of the execution instrument, where the first task flow is a task flow of a type of immediately interrupting in the maintenance flow; ending the current task flow and exiting the second state.
13. The sample analysis system of claim 8, wherein the sample analyzer front end is provided with a sample identification component,
the sample identifying component is used for detecting that the sample rack reaches the preset position when the sample rack is detected by the sample identifying component, and the sample identifying component comprises a sensor and/or a sample scanning component;
the control device is further used for acquiring sample information of the sample to be tested from the sample rack so as to perform a sample testing process based on the sample information; and acquiring a current task flow of the sample analyzer, and judging whether the sample analyzer meets the condition of immediately exiting the second state according to the current task flow.
14. The sample analysis system of claim 8, wherein the first state is an idle state and the second state is a dormant state.
15. A sample testing device for use in a sample analysis system, the sample testing device comprising: a processor, a memory and a computer program stored on the memory and executable on the processor, which when executed by the processor implements the method of any of claims 1-7.
16. A computer readable storage medium having stored thereon a computer program for use in a sample analysis system, which computer program, when executed by a processor, implements the method according to any of claims 1-7.
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| CN114264834B (en) * | 2022-03-02 | 2022-05-24 | 深圳市帝迈生物技术有限公司 | Sample analysis system and sample delivery method thereof |
| CN114578074A (en) * | 2022-05-07 | 2022-06-03 | 深圳市帝迈生物技术有限公司 | Starting method and system of sample detection system and computer readable storage device |
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