CN102830067B - Magnetic block lock structure, and using method and application thereof in biochemical analyzer - Google Patents
Magnetic block lock structure, and using method and application thereof in biochemical analyzer Download PDFInfo
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- CN102830067B CN102830067B CN201210304384.7A CN201210304384A CN102830067B CN 102830067 B CN102830067 B CN 102830067B CN 201210304384 A CN201210304384 A CN 201210304384A CN 102830067 B CN102830067 B CN 102830067B
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Abstract
The invention provides a magnetic block lock structure, which comprises at least three permanent magnetic blocks, wherein a first magnetic block (151) is fixed on a first device, a second magnetic block (152) is fixed on a second device, and a third magnetic block (152) can be movably arranged on the second device. When the first device and the second device are located at the mutual close position, the three magnetic blocks are basically arranged into a straight line, the second magnetic block (152) is located between the first magnetic block (151) and the third magnetic block (153), the magnetisms of two opposite poles of the second magnetic block (152) and the third magnetic block (153) are the same, the magnetisms of two opposite poles of the first magnetic block (151) and the second magnetic block (152) are different, and the third magnetic block (153) can move along the line of the three magnetic blocks. The magnetic block lock structure does not require an operator to use much force and to dismount screws, nuts and the like, and the whole process is convenient and simple.
Description
technical field
The present invention relates to magnetic block lock catch structure and the application on Biochemical Analyzer thereof.
background technology
Along with scientific and technical progress, the bedside in-vitro diagnosis experiment (POCT:Point of Care Testing) in laboratory medicine field is arisen at the historic moment and is rapidly developed." soak and read " of 20 century the fifties appearance dry chemical method (dip-and-read) refers to liquid detecting sample is directly added on the business-like dry type reagent strip into the specific production of disparity items, moisture using tested sample causes specific chemical reaction as solvent, thereby carries out chemico-analytic method.Biochemical dry type test paper method, with features such as its finding speed easy to carry, simple to operate are fast, receives people's concern, also plays a significant role at the scene in fast detecting.Along with the introduction of immune response and molecular biotechnology, the inspection field of medical science dry type test paper method expands to the detection to blood sugar, gestation, blood coagulable status, myocardial damage, acid base equilibrium, infectious diseases etc., and medicine concentration monitor (TMD), alcohol content detection, thrombotest, the analysis of Blood Biochemical Indexes, infectious disease sieve, hormonal readiness and microchip DNA diagnosis and drug abuse detection etc. when operation.Rely on ocular estimate to judge the testing result of dry chemical scrip, can only serve as qualitative judgement, artificial subjective factor is very large on the judgement impact of testing result, is easy to cause erroneous judgement.Therefore for to make the interpretation of quick detection test paper more accurate, supporting miniaturization experimental apparatus progressively grows up with it.These easy and simple to handleization of detecting instrument, report the test are changed in time, accuracy, are more and more subject to clinical medical and nursing personnel, patient and family members' thereof favor.And the data that these detecting instruments obtain can also realize remote wireless transmission to laboratory computer management system or electronic health record.
US Patent No. 4780283 has disclosed a kind of dry chemical test paper analyser.This analyser comprises fixed detection light source, loads the hemispherical workbench of test paper bar.By the interaction between spring, hemispherical workbench being transported to detection light source place detects.Due to the mechanicals efforts of just having utilized between spring, not only on producing, require to have very accurately control procedure, increase production cost, and utilized the interaction of spring to be difficult to control the tram between reaction reagent bar and detection light source, affected testing result.And hemispherical structure has increased the volume of whole analytical instrument.On the other hand, spring is short serviceable life, needs regular replacing spring, and this can make troubles to the user of instrument.
Praxsys Biosystems Inc. company of the U.S. has developed a kind of tachysynthesis detection system that can be used for quantitative and qualitative analysis judgement, in US Patent No. 6136610, disclose, this system by detector and with it supporting Test paper box form.This system is used single channel, once only can detect single clinical samples.Because this detecting instrument once can only detect an index, therefore detection efficiency is lower.
Chinese patent application 200910160639.5 discloses a kind of multi-channel portable colloidal gold test paper device for quick testing, mainly comprises: 4 independently sense channel, ARM data processor, keyboard and LCD parts.The pick-up unit of this invention can complete multiple test item fast and high-throughout.But 4 of this Chinese patent application independently sense channel and whole detector be an entirety, instrument user can not arbitrarily change test event by changing sense channel.
Chinese patent application 200410052202.7 discloses a kind of quick diagnosis lateral flow assays system and method, this detection system comprises 1 master unit and 1 to 20 test module, and being connected to host computer by USB or blue teeth wireless receiver, host computer moves by software control detector.This patented claim also discloses between master unit and test module and has been designed to relatively independent relation, and when master unit breaks down, all proving installations can be removed and ressemble with another master unit.It is a very complicated process that test module described in this patented claim disassembles from master unit, needs a lot of parts of breakdown.On the other hand, described test module is not the structure of a sealing, when sample in the time that retention in the test module being removed has test or test agent, the sample that these are residual or reagent can be exposed in environment, not only pollute environment around, also can form operating personnel's life security dangerous.
summary of the invention
In order to overcome above-mentioned shortcoming of the prior art, one of object of the present invention is to provide the proving installation that a kind of medical test is used.
1, the proving installation that a kind of medical test is used; it is characterized in that: comprise base 101, design on base 101 for transporting the movably microscope carrier 102 of testing element and being positioned at the movably light source transmitter-receiver device 103 above microscope carrier 102; microscope carrier 102 can move back and forth at predefined track; light source transmitter-receiver device 103 can near and away from microscope carrier 102, microscope carrier 102 and the motion track of light source transmitter-receiver device 103 or the extended line of motion track mutually intersect in same plane or orthogonal projection in same plane intersects mutually.
2, according to the proving installation described in 1, it is characterized in that: in the time that certain fixed area on microscope carrier 102 is positioned at orthogonal projection place of light source transmitter-receiver device 103 just, microscope carrier 102 stops mobile, then light source transmitter-receiver device 103 is near that fixed area on microscope carrier 102, detect, after having detected again away from that fixed area on microscope carrier 102.
3, according to the proving installation described in 2, it is characterized in that: proving installation also comprises the support 104 of at least one fixing design on base 101, and described light source transmitter-receiver device 103 designs on described support 104.
4, according to the proving installation described in 3, it is characterized in that: described proving installation comprises at least two motors, drive respectively described microscope carrier 102 and light source transmitter-receiver device 103.
5, according to the proving installation described in 4, it is characterized in that: described electro-motor is stepper motor 107,130.
6, according to the proving installation described in 5, it is characterized in that: on microscope carrier 102, be fixed with rack-plate 111, be arranged on described support with the stepper motor 107 of gear 108, the gear 108 on stepper motor is connected with a joggle with the rack-plate 111 on microscope carrier 102, drives microscope carrier 102 to move.
7, according to the proving installation described in 3, it is characterized in that: on base 101, be designed with left socle 104, right support 105, be designed with upper bracket 106 on described left socle and right support, light source transmitter-receiver device 103 designs on upper bracket 106.
8, according to the proving installation described in 1, it is characterized in that: light source transmitter-receiver device 103 comprises the optical coupled switch 132 that light source emitter 131, optical pickup apparatus and control light source transmitter-receiver device move.
9, according to the proving installation described in 8, it is characterized in that: described smooth lotus root switch 132 has lightening hole 133, on light source transmitter-receiver device, have shutter 134, described shutter 134 has the lightening hole of blocking 133 and leaves 133 two positions of lightening hole with respect to lightening hole 133.
10, according to the proving installation described in 9, it is characterized in that: in the downward operational process of light source transmitter-receiver device 103, when shutter 134 is positioned at lightening hole 133 tops of light lotus root switch 132, now light path is unimpeded, power supply keeps power supply state always, make light source emitter 131 continue to move downward under electro-motor 130 rotates, in the time that shutter 134 has stopped the lightening hole 133 of light lotus root switch 132, light path is cut off, thereby close the power supply of the electro-motor 130 of light source transmitter-receiver device 103, and open light source transmitter-receiver device 103 and carry out the analysis of sample.
11, according to the proving installation described in any one of 1-10, it is characterized in that: base 101 is fixedly designed with track base 112, microscope carrier 104 is fixedly designed with guide rail 113, the combination of sliding of described guide rail 113 and track base 112.
Two of object of the present invention is to provide a kind of medical detecting analyzer.
12, a kind of medical detecting analyzer, it is characterized in that: comprise a master control set 10 and at least one proving installation 100, wherein, master control set 10 comprises supply unit 11, control device, testing result output unit and the storage chamber 15 that is no less than proving installation number, proving installation 100 comprises the microscope carrier 102 for carrying detecting element and detection sample and is positioned at the light source transmitter-receiver device 103 of microscope carrier 102 tops, proving installation 100 be placed in the storage chamber 15 of master control set and with the supply unit 11 of master control set, control device and the electrical connection of testing result output unit, the microscope carrier 102 of control device control proving installation moves back and forth in certain direction, light source transmitter-receiver device 103 in the direction substantially vertical with microscope carrier 102 moving directions, do near and away from the movement of microscope carrier, and detect the change color parameter that is placed in the detecting element on microscope carrier 102, then this parameter is delivered to control device, after control device is processed, via testing result output unit output detections result.
13, according to the medical detecting analyzer described in 12, it is characterized in that: proving installation 100 can repeated multiple times extraction and group enter master control set 10.
14, according to the medical detecting analyzer described in 13, it is characterized in that: between the inwall of the storage chamber 15 of the outer wall of proving installation 100 and master control set 10, be designed with rail structure.
15, according to the medical detecting analyzer described in 14, it is characterized in that: rail structure comprises the guide rail 16 and the slide block structure 120 that are placed on storage chamber 15 inwalls and proving installation outer wall, described slide block structure 120 can be in the interior slip of the guide rail of storage chamber 15 16.
16, according to the medical detecting analyzer described in any one of 12-15, it is characterized in that: the proving installation 100 that comprises two or more, each proving installation can detect the identical or different parameter of same species detection sample, also can detect the identical or different parameter of variety classes detection sample.
17, according to the medical detecting analyzer described in 15, it is characterized in that: also comprise at least one reagent storage unit 18, this reagent storage unit 18 is interior can place some detecting elements.
18, according to the medical detecting analyzer described in 17, it is characterized in that: the storage chamber 15 in master control set 10 is optionally accommodated proving installation 100 or reagent storage unit 18, be that storage chamber 15 can not only be received proving installation 100, also can receive reagent storage unit 18.
19, according to the medical detecting analyzer described in any one of 12-15 and 17-18, it is characterized in that: wherein testing result output unit comprises printer 14 and/or display 13.
20, according to the medical detecting analyzer described in any one of 12-15 and 17-18, it is characterized in that: wherein control device comprises touch-screen display 13, this touch-screen display 13 provides operation interface.
21, according to the medical detecting analyzer described in any one of 12-15 and 17-18, it is characterized in that: also comprise the latching system with proving installation 100 snap closes or release by master control set 10.
22, according to the medical detecting analyzer described in 21, it is characterized in that: described latching system comprises three permanent magnet blocks, wherein the first and second magnetic patch are placed in the shell of master control set 10, the 3rd magnetic patch is fixed on the shell of proving installation 100, when proving installation is housed in the storage chamber 15 of master control set when interior fully, three magnetic patch are arranged in straight line substantially, the second magnetic patch is first and the 3rd between magnetic patch, second contrary with the two relative utmost point magnetic of the 3rd magnetic patch (for example one is the S utmost point, another is the N utmost point), first two utmost point Magnetic Phase same (being all for example the N utmost point or the S utmost point) that magnetic patch is relative with the second magnetic patch, the first magnetic patch can move along the line of three magnetic patch with proving installation (100).
Three of object of the present invention is to provide a kind of Biochemical Analyzer.
23, a kind of Biochemical Analyzer, it is characterized in that: comprise a master control set 10 and at least one proving installation 100, master control set 10 comprises at least one storage chamber 15, proving installation 100 is incorporated in described storage chamber 15, in storage chamber 15, be designed with guide rail 16, proving installation 100 is designed with slide block structure, and described slide block structure can be in the interior slip of the guide rail of storage chamber 15 16, thus reposefully by proving installation 100 from shifting out in storage chamber 15 or 100 groups of proving installations being entered in storage chamber 15.
24, according to the Biochemical Analyzer described in 23, it is characterized in that: the two side of storage chamber 15 is designed with respectively guide rail 16, or have guide rail 17 in the bottom design of storage chamber, or be all designed with guide rail in two side and the bottom of storage chamber.
25, according to the Biochemical Analyzer described in 24, it is characterized in that: described slide block structure comprises the take-up housing 120 designing in the side of proving installation base 101, is provided with slide block 121 in take-up housing 120, described slide block 121 can be in the interior slip of the guide rail of storage chamber 15 16.
26, according to the Biochemical Analyzer described in 24, it is characterized in that: described slide block structure comprises the take-up housing 120 designing in the bottom of proving installation base 101, is provided with slide block 121 in take-up housing 120, described slide block 121 can be in the interior movement of the guide rail of storage chamber 15 17.
27, according to the Biochemical Analyzer described in 23, it is characterized in that: comprise that two or more proving installation 100 and quantity are no less than the storage chamber 15 of proving installation number.
28, according to the Biochemical Analyzer described in 27, it is characterized in that: between described proving installation 100, be separate work.
29, according to the Biochemical Analyzer described in 23, it is characterized in that: also comprise at least one reagent storage unit 18, have a storage chamber 15 at least for receiving reagent storage unit 18, remaining storage chamber is used for receiving proving installation 100.
30, according to the Biochemical Analyzer described in 29, it is characterized in that: in described reagent storage unit, have reagent storage frame 19.
31, according to 23 to 30 any one described in Biochemical Analyzer, it is characterized in that: between described proving installation 100 or reagent storage frame 19 and master control set 10, mutually fasten by magnetic block lock catch structure.
32, according to the Biochemical Analyzer described in 31, it is characterized in that: described magnetic block lock catch structure comprises three permanent magnet blocks, wherein the first magnetic patch 151 and the second magnetic patch 152 are placed in the shell of master control set 10, the 3rd magnetic patch 153 is fixed on the shell of proving installation 100, when proving installation is housed in the storage chamber 15 of master control set when interior fully, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, (for example one is the S utmost point to the two relative utmost point magnetic of the second magnetic patch 152 and the 3rd magnetic patch 153 on the contrary, another is the N utmost point), first two utmost point Magnetic Phase same (being all for example the N utmost point or the S utmost point) that magnetic patch 151 is relative with the second magnetic patch 152, the first magnetic patch 151 can move along the line of three magnetic patch.
33, according to the Biochemical Analyzer described in 32, it is characterized in that: the first magnetic patch 151 designs on proving installation backboard 126, the second magnet piece 152 designs in master control set 10, on master control set bonnet, being designed with two bracing frames, 154, the three magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.
34, according to the Biochemical Analyzer described in 23, it is characterized in that: master control set 10 also comprises primary power 11, master switch 12, guidance panel 13 and printer 14, master switch 12, guidance panel 13 and printer 14 are electrically connected with primary power 11.
35, according to the Biochemical Analyzer described in 23, it is characterized in that: master control set 10 also comprises usb 19, fan 20 and general supply access port 21.
36, according to the Biochemical Analyzer described in 23, it is characterized in that: proving installation 100 comprises a base 101, the microscope carrier that transport test strip 102 of design on base 101, be positioned at the light source transmitter-receiver device 103 of microscope carrier 102 tops, on base 101, be at least fixedly designed with a support, described light source transmitter-receiver device 103 designs on described support, at least one side at microscope carrier 102 is designed with rack-plate 111 regularly, on described support, be designed with stepper motor 107, gear 108 on stepper motor is connected with a joggle with the rack-plate 111 on microscope carrier 102, stepper motor driven gear rotates, gear driven microscope carrier moves in proving installation.
37, according to the Biochemical Analyzer described in 36, it is characterized in that: described light source transmitter-receiver device 103 comprises the optical coupled switch 132 that promotes motor 130, light source emitter 131, optical pickup apparatus and control light source transmitter-receiver device movement position that light source emitter 131 moves up and down.
38, according to the Biochemical Analyzer described in 23, it is characterized in that: described master control set 10 and proving installation 100 electric connections.
39, according to the Biochemical Analyzer described in 38, it is characterized in that: master control set 10 is connected by power connector 140 with proving installation 100.
Four of object of the present invention is to provide another kind of Biochemical Analyzer.
40, a kind of Biochemical Analyzer, the proving installation 100 that comprises master control set 10 and be electrically connected with master control set 10, it is characterized in that: master control set 10 comprises supply unit 11 and control device, proving installation 100 comprises that movably microscope carrier 102 can be made light source transmitter-receiver device 103 approaching and that move away from microscope carrier with being positioned on microscope carrier.
41, according to the Biochemical Analyzer described in 40, it is characterized in that: described control device comprises with the shell of master control set 10 by hinged guidance panel 13 the guidance panel 13 0-180 degree that can overturn taking hinge as rotating shaft.
42, according to the Biochemical Analyzer described in 41, it is characterized in that: the operation interface of described guidance panel 13 is downward, when guidance panel 13 overturns 90-180 while spending taking hinge as rotating shaft, its guidance panel 13 is in opening.
43, according to the Biochemical Analyzer described in 41, it is characterized in that: upwards, when guidance panel 13 overturns 0-90 while spending taking hinge as rotating shaft, its guidance panel 13 is in opening for the operation interface of described guidance panel 13.
44, according to the Biochemical Analyzer described in 43, it is characterized in that: guidance panel 13 is provided with support 24, the two ends of support 24, respectively against the shell of guidance panel 13 and master control set 10, make the shell of guidance panel 13 and master control set 10 keep the angle between between 0-90 degree.
45, according to the Biochemical Analyzer described in any one of 40-44, it is characterized in that: described guidance panel 13 is LCD or LED display panel.
46, according to the Biochemical Analyzer described in 45, it is characterized in that: described guidance panel 13 is touch-screen LCD or the LED display panels that can carry out touch screen operation.
47, according to the Biochemical Analyzer described in any one of 40-44, it is characterized in that: in master control set 10, be provided with storage chamber 15, proving installation 100 inserts storage chamber in the mode of drawer or extracts out from storage chamber.
48, according to the Biochemical Analyzer described in 47, it is characterized in that: the outer wall of the inwall of storage chamber 15 and proving installation 100 is provided with the railroad cooperatively interacting.
49, according to the Biochemical Analyzer described in 48, it is characterized in that: rail structure comprises guide rail 16 and slide block structure 120, and described slide block structure can move on guide rail.
Five of object of the present invention is to provide a kind of magnetic block lock catch structure.
50, a kind of magnetic block lock catch structure, comprise at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on first device, the second magnetic patch 152 is fixed on the second device, the 3rd magnetic patch 153 is placed on the second device movably, when the first and second devices are during in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 for example, with (being all the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch.
51, according to the magnetic block lock catch structure described in 50, it is characterized in that: on the second device, be designed with two supports 154 and two ends and be movably attached to the spring leaf 155 of support 154, described the 3rd magnetic patch 153 is fixedly connected with spring leaf 155.
52, according to the magnetic block lock catch structure described in 50, it is characterized in that: on the second device, be designed with two slide bars 156 and can on slide bar 156, slide by slide bar button 157 with slide bar button 157, the three magnetic patch 153 that are enclosed within on slide bar 156.
53, according to the magnetic block lock catch structure described in 50, it is characterized in that: on the second device, be designed with two springs, 158, the three magnetic patch 153 and be connected with spring 158 by snak link 159.
Six of object of the present invention is to provide a kind of magnetic block lock catch structure that utilizes and makes two devices mutual snap closes and the method separating.
54, a kind of magnetic block lock catch structure that utilizes makes two devices mutual snap closes and the method separating, described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on first device, the second magnetic patch 152 is fixed on the second device, the 3rd magnetic patch 153 is placed on the second device movably, when the first and second devices are during in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 for example, with (being all the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch, described method comprises the steps: 1) by close to the second device that is fixed with described the second magnetic patch 152 first device that is fixed with described the first magnetic patch 151, and make described the 3rd magnetic patch 153 and described the second magnetic patch 152 keep distance enough far away, together with the first magnetic patch 151 passes through magnetic-adsorption with the second magnetic patch 152, thereby by first device and the mutual snap close of the second device, 2) promotion the 3rd magnetic patch 153 is close to the second magnetic patch 152, mutual repulsive force between the 3rd magnetic patch 153 and the second magnetic patch 152 and the first magnetic patch 151, weaken the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 153, thereby first device and the second device are separated from each other.
Seven of object of the present invention is to provide a kind of Biochemical Analyzer with magnetic block lock catch structure.
55, a kind of Biochemical Analyzer with magnetic block lock catch structure, comprise master control set 10 and proving installation 100, in master control set 10, be provided with storage chamber 15, proving installation 100 is housed in storage chamber 15, it is characterized in that: described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch 151 is fixed on proving installation 100, the second magnetic patch 152 is fixed on master control set 10, the 3rd magnetic patch 153 is placed on master control set 10 movably, when master control set 10 and electricity testing device 100 are during in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch 152 is between the first magnetic patch 151 and the 3rd magnetic patch 153, the two relative utmost point Magnetic Phases of the second magnetic patch 152 and the 3rd magnetic patch 153 for example, with (being all the N utmost point or the S utmost point), two utmost point magnetic that the first magnetic patch 151 is relative with the second magnetic patch 152 are different, and (for example one is the S utmost point, another is the N utmost point), the 3rd magnetic patch 153 can move along the line of three magnetic patch.
56, according to the Biochemical Analyzer described in 55, it is characterized in that: on master control set 10, be designed with two bracing frames 154) the 3rd magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.
57, according to the Biochemical Analyzer described in 55, it is characterized in that: on master control set 10, being designed with two slide bars, 156, the three magnetic patch 153 can slide by slide bar button 157 on slide bar 156.
58, according to the Biochemical Analyzer described in 55, it is characterized in that: on master control set 10, be designed with two springs, 158, the three magnetic patch 153 and mutually conflict by snak link 159 and spring 158.
Eight of object of the present invention is to provide a kind of method of testing that adopts Biochemical Analyzer to measure parameters of biological samples.
59, adopt Biochemical Analyzer to measure a method of testing for parameters of biological samples, it is characterized in that: comprise the following steps: 1) opening power, Biochemical Analyzer is started shooting and is entered startup self-detection step; 2) after startup self-detection is passed through, Biochemical Analyzer enters preheating step; 3), in the time that the probe temperature of Biochemical Analyzer meets predefined temperature conditions, prompting is put into testing element and is detected sample; 4) Biochemical Analyzer starts test; 5) after having tested, output test result; 6) prompting is taken out used testing element and is detected sample; 7) whether prompting detects and finishes; 8) do not finish if select, prompting is put into new testing element and is detected sample, then repeating step 4)-6); 9) finish if select, shutdown, finishes test.
60, according to the method for testing described in 59, it is characterized in that: described Biochemical Analyzer comprises master control set 10 and at least one proving installation 100, startup self-detection step comprises and checks that whether the state of each equipment is normal, and the quantity of checkout device 100.
61, according to the method for testing described in 60, it is characterized in that: in the time that the quantity of proving installation 100 is equal to, or greater than two, after the step of passing through in startup self-detection, before preheating step, also comprise the step of selecting unlatching any platform or which platform proving installation 100 to test.
62, according to the method for testing described in 61, it is characterized in that: selecting after the step that proving installation 100 tests or after preheating step, also comprising the step that the test approaches that will carry out selected proving installation 100 is selected.
63, according to the method for testing described in 61, it is characterized in that: put into testing element and detect after sample, analyser starts before test, also comprises that the test approaches that will carry out selected proving installation 100 carries out the step of automatic decision.
64, according to the method for testing described in 63, it is characterized in that: on testing element, be accompanied with the beacon information of test approaches, automatic decision test approaches after the beacon information on Biochemical Analyzer read test element.
65, according to the method for testing described in 64, it is characterized in that: each proving installation 100 completes after test, whether Biochemical Analyzer prompting test finishes, finish if select, close this TV station proving installation 100, if do not carry out any selection, this TV station proving installation 100 cut out after the idle schedule time.
66, according to the method for testing described in 65, it is characterized in that: after whole proving installation 100 cuts out, Biochemical Analyzer shutdown.
67, according to the method for testing described in 59, it is characterized in that: between the master control set 10 of Biochemical Analyzer and at least one proving installation 100, be provided with guide rail, at least one proving installation 100 can be in the interior slip of master control set 10.
68, according to the method for testing described in 67, it is characterized in that: Biochemical Analyzer also includes the reagent storage unit 18 that appearance profile is identical or close with proving installation 100 with size, in master control set 10, be provided with the storage chamber 15 that profile and size and proving installation 100 and reagent storage unit 18 match, storage chamber can optionally be accommodated proving installation 100 or reagent storage unit 18, be that storage chamber 15 can not only be received proving installation 100, also can receive reagent storage unit 18.
69, according to the method for testing described in 68, it is characterized in that: between reagent storage unit 18 and master control set 10, be provided with guide rail.
Owing to adopting technique scheme, the present invention has brought following beneficial effect:
In proving installation by the slide block on proving installation mobile cooperation the in master control set guide rail, can realize proving installation and be installed on master control set or by proving installation and disassemble from master control set.This operating process is simple, convenient.
Owing to can also receiving reagent storage unit in storage chamber, operator can be placed on the reagent of needs in the reagent rack of reagent storage unit in advance, just can from described reagent storage frame, take out easily the reagent needing when detection.If the proving installation of certain type is used for a long time, its corresponding reagent storage unit also can long-term storage in master control set, form man-to-man relation with proving installation, prevent from misusing reagent.Reagent storage unit is incorporated in master control set, makes operating table surface be unlikely to pile with reagent bottle, prevents the hazard events such as reagent bottle tipping.
Magnetic block lock catch structure of the present invention has utilized the two like magnetic poles attract each other of magnetic patch, the principle that the opposite sex is repelled each other, and has effectively realized the assembling between proving installation and master control set.Magnetic block lock catch structure of the present invention, does not need operator to use a lot of strength, does not need operator to dismantle such as a lot of screw nuts etc. yet, and whole process is very simple and convenient.
The stepper motor driven wheel that utilizes of the present invention drives the rack-plate operation on microscope carrier, thereby drive the motion of test paper test paper carrier bench, not only improve test speed, and the driving effect of stepper motor continuous and stable, can stablize and accurately microscope carrier is transported to tram.
The track base that the bottom of microscope carrier is designed with on guide rail and base is used in conjunction with, and makes level and smooth the moving in proving installation of microscope carrier energy, has reduced the interference of noise.
Baffle plate of the present invention not only plays good protection to the test strips microscope carrier in proving installation and light source transmitter-receiver device, makes microscope carrier and light source transmitter-receiver device avoid external force collision, prevents dust pollution.Simultaneously in the time that proving installation is deposited separately, because proving installation is the structure of a sealing, when sample in the time that retention in the proving installation being removed has test or test agent, reagent or sample residual on microscope carrier can not be exposed in external environment, prevent the pollution to surrounding environment and operator.
Biochemical Analyzer of the present invention also comprises the supporting structure for support operation panel, because guidance panel is in the time establishing, has thereafter stent support, and operator is in the time using panel button, and guidance panel can not cave in backward.
brief description of the drawings
Fig. 1 Biochemical Analyzer schematic diagram;
Fig. 2 Biochemical Analyzer guidance panel open mode schematic diagram;
A view that proving installation is drawn out of in Fig. 3 Biochemical Analyzer;
In Fig. 4 Biochemical Analyzer, there is reagent storage cell schematics;
The rear structure schematic diagram of Fig. 5 Biochemical Analyzer and proving installation;
The guidance panel of Fig. 6 Biochemical Analyzer is by the second design diagram of stent support;
The proving installation inner structure schematic diagram of Fig. 7 Biochemical Analyzer;
The cut-open view of the proving installation A-A direction along the line of Fig. 8 Biochemical Analyzer;
The proving installation door of the proving installation of Fig. 9 Biochemical Analyzer is opened schematic diagram;
The schematic diagram that in Figure 10 the first magnetic block lock catch structure, the first magnetic patch and the second magnetic patch attract each other;
The first magnetic patch and the separated schematic diagram of the second magnetic patch in Figure 11 the first magnetic block lock catch structure;
Figure 12 the second magnetic block lock catch structure schematic diagram;
The third magnetic block lock catch structure schematic diagram of Figure 13;
Figure 14 Biochemical Analyzer test flow chart.
embodiment
Below in conjunction with concrete accompanying drawing, the present invention will be described in detail.These specific embodiments are only limited the enumerating under spirit of the present invention, do not get rid of one of ordinary skill in the art prior art and the present invention in conjunction with and other specific embodiments of producing.
As shown in Figure 1, Biochemical Analyzer 1 of the present invention comprises a master control set 10 and one or an above separate proving installation 100, and master control set 10 is connected by electric connector 140 and wire with proving installation 100.The instruction that each proving installation 100 can transmit according to master control set 10, completes independently of one another test item and testing result is transferred to master control set 10 and export.Between each proving installation 100, be designed to relatively independent relation, the dismounting that proving installation 100 can be freely carries out repeatedly with master control set 10.
As shown in Figures 1 to 6, in the casing of master control set 10, include after primary power 11(connects external goods electricity consumption and power to the each several part of Biochemical Analyzer).Master control set 10 also includes master switch 12, guidance panel 13 and the printer 14 of analyser.Master switch 12, guidance panel 13 and printer 14 are electrically connected with primary power 11 respectively.Guidance panel 13 is touch display screens, both can show interface and the testing result of testing process, and the person's touch screen that is not convenient to operation again operates.
In the casing of master control set 10, be provided with side by side the storage chamber 15 that more than one or one size and proving installation 100 are substantially suitable.For proving installation can be quick smoothly pushed in the storage chamber 15 of master control set, the at least two side of storage chamber 15 is designed with respectively guide rail 16, or there is guide rail 17 in the bottom design of storage chamber 15, or be all designed with guide rail in two side and the bottom of storage chamber.Described guide rail coordinates with slide block or pulley (not shown) on proving installation.When proving installation be assembled into master control set or the process that disassembles from master control set in, slide block or pulley on proving installation slide in guide rail, guiding proving installation enters the storage chamber of master control set or leaves storage chamber 15.
As shown in Figure 4, in described storage chamber 15, also can put into the reagent storage unit 18 that size and shape is substantially suitable with proving installation 100, described reagent storage unit 18 is interior can arrange one or more reagent storage frame 19, for depositing the testing element of test use, this testing element can be test agent or reagent barrel etc.The advantage of this design is, can be according to actual needs, and the whole installation testing devices 100 of storage chamber 15 in master control set 10, or part installation testing device 100, other installation reagent storage unit 18, thus make design more flexible.Biochemical Analyzer 1 as shown in Figure 4, has comprised a master control set 10, two proving installations 100 and reagent storage unit 18.As more changeable embodiment more, Biochemical Analyzer 1 can comprise a master control set 10, one to ten, even ten above proving installations 100 and one to ten, the arbitrarily combination according to need of even ten above reagent storage unit 18, and the quantity of proving installation 100 and storage unit 18.The reagent that operator can need when detecting is placed in reagent storage frame 19 in advance.In the time detecting, operator can take out corresponding reaction reagent easily from the reagent storage unit of analyser.If proving installation is used for a long time, its corresponding reagent storage unit also can long-term storage in master control set, form man-to-man relation with proving installation, prevent from misusing reagent.Reagent is all sorted out and is placed in reagent storage unit in addition, makes operating table surface be unlikely to pile with reagent bottle, prevents the hazard events such as reagent bottle tipping.
On the shell of master control set 10, be equipped with USB interface 26, fan 20, general supply access port 21 etc.For the proving installation 100 that makes to be pushed into stably remains in storage chamber 15, on the bonnet of master control set, the position of corresponding each proving installation can also comprise bonnet lock hole 22.
Guidance panel 13 can be LCD, the LED panel that LCD, LED touch panel or some have button.Guidance panel 13 is connected with master control set 10 by hinge 23, also can be connected with master control set 10 with support 24 by hinge (not shown).
As shown in Figure 7 to 9, proving installation 100 comprises a base 101, and the microscope carrier 102 that transports test strip designs on base, and light source transmitter-receiver device 103 is positioned at the top of microscope carrier 102.On base 101, be fixedly designed with left socle 104 and right support 105, left and right support surrounds microscope carrier 102 therein.Light source transmitter-receiver device 103 is arranged on the support of left and right, or is fixedly designed with upper bracket 106 on the support of left and right, and light source transmitter-receiver device 103 is installed on upper bracket 106.Microscope carrier 102 can move back and forth at predefined track; light source transmitter-receiver device 103 can near and away from microscope carrier 102, microscope carrier 102 and the motion track of light source transmitter-receiver device 103 or the extended line of motion track mutually intersect in same plane or orthogonal projection in same plane intersects mutually.
On at least one support 104 or 105, be designed with stepper motor 107, gear 108 is housed on stepper motor.The microscope carrier 102 that transports test strip comprises the pallet 110 for carrying test strip 109.At least one side at microscope carrier 102 is designed with rack-plate 111 regularly.Described gear 108 engages with the rack-plate 111 on microscope carrier 102.In the time that stepper motor is worked, order about driven wheel and rotate, and then order about rack-plate 111 and make linear running, thereby the microscope carrier being connected with rack-plate is delivered to test zone or exit from test zone.Stepper motor is higher to the ratio of precision of motion, therefore, when the motion of gear driven rack-plate, has not only improved the speed of transporting test paper, and has improved stability and the accuracy of test.
The medium position of base 101 is fixedly designed with track base 112, this track base 112 is used in conjunction with the guide rail 113 on test strips microscope carrier 102, microscope carrier 102 can slide along track base in proving installation, arrives detection position or exits test zone thereby transport test-strips.Described guide rail 113 designs in the bottom of microscope carrier 102.
On microscope carrier, be positioned at test strips test zone below have a temperature control equipment 114.In the time that the environment temperature of test does not meet predefined temperature range, temperature control equipment will regulate temperature (for example heating) automatically, make the temperature of test environment meet predefined temperature range.Temperature control equipment comprises resistive heating device, and transmits temperature by potsherd or sheet metal.
The left and right sides of proving installation base 101 can also respectively be mounted with a take-up housing 120, and take-up housing 120 is bolted on base 101.The fixing design of slide block 121 is on take-up housing 120, this slide block 121 can be free to slide in the guide rail 16 of storage chamber 15 sidewalls, thereby drive whole proving installation in the interior movement of storage chamber 15, proving installation is pushed into storage chamber and prepares to carry out the detection of analyte, or is moved out of storage chamber.Can also be arranged on the bottom of base with the take-up housing of slide block, be used in conjunction with the bottom guide track 17 in storage chamber.As changing design, take-up housing 120 and slide block 121 can be also an entirety, can also be bars matching with guide rail 16.
For better protection test microscope carrier and light source transmitter-receiver device, can also respectively be designed with baffle plate 122-126, i.e. right baffle plate 122, right baffle-plate 123, overhead gage 124, front apron 125 and backboard 126 all around at proving installation 100.On front apron 125, be designed with a proving installation door 127, proving installation door 127 can be connected through the hinge with front apron 125.In the time that proving installation does not use or detecting, proving installation door is closed.In the time that the test strips microscope carrier in proving installation need to transport test strip, proving installation door is opened, and handled easily person deposits or take out test paper.Described baffle plate plays good protection to the test strips microscope carrier in proving installation and light source transmitter-receiver device, makes microscope carrier and light source transmitter-receiver device avoid external force collision, and can prevent dust pollution.When proving installation is during by whole taking out, reagent or sample residual on microscope carrier can not be exposed in external environment, prevent the pollution to environment simultaneously.
Light source transmitter-receiver device 103 comprises the preferred stepper motor of electro-motor 130(that promotion light source transmitter-receiver device moves up and down), light source emitter 131.Light source transmitter-receiver device 103 also comprises the optical coupled switch 132 of controlling light supply apparatus movement position, and described smooth lotus root switch 132 is electrically connected with described electro-motor 130, moves and brakes for controlling described electro-motor 130.Described smooth lotus root switch 132 has lightening hole 133, and light source transmitter-receiver device has shutter 134.Described shutter 134 has the lightening hole of blocking 133 and leaves 133 two positions of lightening hole with respect to lightening hole 133.When in the downward operational process of light source transmitter-receiver device, when shutter 134 is positioned at lightening hole 133 tops of light lotus root switch 132, now light path is unimpeded, and power supply keeps power supply state always, and light supply apparatus continues to move downward under electro-motor 130 rotates.In the time that shutter 134 has stopped the lightening hole 133 of light lotus root switch 132, light path is cut off, thereby closes the power supply of electro-motor 130, and light supply apparatus is no longer descending, opens sample detection light source 131 simultaneously sample is carried out to determination and analysis.
Each proving installation 100 can also comprise independently microprocessor, can carry out the movement position, test environment temperature and the heating plate heating supervisor that include but not limited to for example control light source emitter, monitoring pallet, and transmit data by data transmission interface to the external world.
Proving installation 100 also can comprise power interface and data transmission interface, realizes to proving installation power supply test transmission result.Proving installation 100 also can be with integrated electric connector 140.Described electric connector is the device that power interface and data transmission interface are integrated, and this just makes proving installation have more space to deposit other accessories, has also reduced the operation of producing, and enhances productivity.Proving installation is connected with master control set by electric connector, accepts master control set proving installation is powered, or transfer data to the data output device of master control set.The electric connector of proving installation also can be connected on other data output device.
The detection light source adopting on each proving installation can be identical or different.When the detection light source that adopts when multiple proving installations is identical, can improve speed and the efficiency of detection.If the detection light source that proving installation adopts is different, each proving installation can be measured the identical or different biochemical parameter of identical or different samples, thereby realizes a tractor serves several purposes.Array mode between master control set and proving installation that other are any is all suitable.
In order to ensure that proving installation is well fixed on master control set, can on proving installation and master control set, arrange proving installation is fixed to the buckle structure on master control set.Described buckle structure can be fixed form, buckle snap close or the magnetic patch snap close of screw thread snap close (for example bolt and nut, screw and threaded hole).The structure of described magnetic patch snap close, as shown in Figure 10 to Figure 13, comprises at least three magnetic patch, the first magnetic patch 151, the second magnetic patch 152 and the 3rd magnetic patch 153.The first magnetic patch 151 designs on first device, and the second magnetic patch 152 and the 3rd magnetic patch 153 design on the second device.The magnetic different (being respectively the S utmost point and the N utmost point) of two faces that the first magnetic patch 151 is relative with the second magnetic patch 152, the Magnetic Phase of two faces that the second magnetic patch 152 is relative with the 3rd magnet 153 is with (be all the S utmost point or be all the N utmost point).The first magnetic patch 151, the second magnetic patch 152 and the 3rd projection of magnetic patch 153 in the direction perpendicular to its opposite face are roughly overlapping.If by two mutual snap closes of device while living, install close by pushing to the first device of the first magnetic patch 151 with second of the second magnetic patch 152, together with first device finally passes through magnetic-adsorption with the second device, now, the 3rd magnetic patch 153 is away from the second magnetic patch 152.If two devices are separated from each other, now push the 3rd magnetic patch 153 to second magnetic patch 152 close, utilize the mutual repulsive force between the 3rd magnetic patch 153 and the second magnetic patch 152 and the first magnetic patch 151, weaken the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 153, thereby first device and the second device are separated from each other.
In the embodiment of Biochemical Analyzer of the present invention as shown in Figure 10 to Figure 11, the first magnetic patch 151 designs on the backboard 126 of proving installation 100.The second magnetic patch 152 is entrenched in the bonnet lock hole 22 of master control set 10.On master control set bonnet, be designed with two bracing frames 154, support frame as described above 154 designs respectively the both sides at bonnet lock hole.The 3rd magnetic patch 153 is connected with bracing frame 154 by spring leaf 155.The magnetic different (being respectively the S utmost point and the N utmost point) of two faces that the first magnetic patch 151 is relative with the second magnetic patch 152, the Magnetic Phase of two faces that the second magnetic patch 152 is relative with the 3rd magnetic patch 153 is with (be all the S utmost point or be all the N utmost point).Shown in Figure 10 is that proving installation 100 is pushed into the state in the storage chamber 15 of master control set 10, now, there is a natural attraction between the sexes because of magnet for the first magnetic patch 151 and the second magnetic patch 152, and this magnetic attraction is inhaled on master control set proving installation firmly, and can from master control set, not skid off.As shown in figure 11, in the time that needs are extracted proving installation 100 out, the 3rd magnetic patch 153 is pushed away to the second magnetic patch direction, because the polarity of two faces that the second magnetic patch 152 is relative with the 3rd magnetic patch 153 is identical, and the polarity of the face that the 3rd magnetic patch 153 is relative with the first magnetic patch 151 is also identical, according to the principle of the two like magnetic poles repel each other of magnet, the 3rd magnetic patch 153 has a repulsive interaction to the first magnetic patch and the second magnetic patch, has weakened the magnetic attraction between the first magnetic patch 151 and the second magnetic patch 152.Close along with the 3rd magnetic patch 153, this repulsive force can basic neutralisation the first magnetic patch 151 and the second magnetic patch 152 between magnetic attraction.Thereby proving installation 100 just can be extracted out easily from the storage chamber of master control set.
Figure 12 is the another kind of embodiment of magnetic block lock catch structure, and the 3rd magnetic patch 153 can slide by slide bar button 157 on slide bar 156.Figure 13 is the another kind of embodiment of magnetic block lock catch structure, and the 3rd magnetic patch 153 is conflicted mutually by snak link 159 and spring 158, and spring has the state that is compressed and unfold by the 3rd magnetic patch.
Between master control set and proving installation, testing process as shown in figure 14.Workflow is: first opening power, Biochemical Analyzer is started shooting and is entered startup self-detection program, after startup self-detection finishes, enters preheating program, in the time that the probe temperature of Biochemical Analyzer meets predefined temperature range, detector is in waiting for test mode, and operator selects the proving installation that need to test, puts into after test paper bar, analyser starts test, after test finishes, output test result, take out test paper bar.Again put into new test paper bar if also will carry out the detection of next sample, start the mensuration of a new round.If all samples has all been tested, shutdown.
Claims (9)
1. a magnetic block lock catch structure, comprise at least three permanent magnet blocks, wherein the first magnetic patch (151) is fixed on first device, the second magnetic patch (152) is fixed on the second device, the 3rd magnetic patch (153) is placed on the second device movably, when the first and second devices are during in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch (152) is positioned between the first magnetic patch (151) and the 3rd magnetic patch (153), the two relative utmost point Magnetic Phases of the second magnetic patch (152) and the 3rd magnetic patch (153) are same, two utmost point magnetic that the first magnetic patch (151) is relative with the second magnetic patch (152) are different, the 3rd magnetic patch (153) can move along the line of three magnetic patch.
2. magnetic block lock catch structure according to claim 1, it is characterized in that: on the second device, be designed with two supports (154) and two ends and be movably attached to the spring leaf (155) of support (154), described the 3rd magnetic patch (153) is fixedly connected with spring leaf (155).
3. magnetic block lock catch structure according to claim 1, it is characterized in that: on the second device, be designed with two slide bars (156) and be enclosed within the slide bar button (157) on slide bar (156), the 3rd magnetic patch (153) can be by slide bar button (157) in the upper slip of slide bar (156).
4. magnetic block lock catch structure according to claim 1, is characterized in that: on the second device, be designed with two springs (158), the 3rd magnetic patch (153) is connected with spring (158) by snak link (159).
5. one kind is utilized magnetic block lock catch structure to make two devices mutual snap closes and the method separating, described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch (151) is fixed on first device, the second magnetic patch (152) is fixed on the second device, the 3rd magnetic patch (153) is placed on the second device movably, when the first and second devices are during in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch (152) is positioned between the first magnetic patch (151) and the 3rd magnetic patch (153), the two relative utmost point Magnetic Phases of the second magnetic patch (152) and the 3rd magnetic patch (153) are same, two utmost point magnetic that the first magnetic patch (151) is relative with the second magnetic patch (152) are different, the 3rd magnetic patch (153) can move along the line of three magnetic patch, described method comprises the steps: 1) by close to the second device that is fixed with described the second magnetic patch (152) first device that is fixed with described the first magnetic patch (151), and make described the 3rd magnetic patch (153) and described the second magnetic patch (152) keep distance enough far away, the first magnetic patch (151) and the second magnetic patch (152) are by magnetic-adsorption together, thereby by first device and the mutual snap close of the second device, 2) promotion the 3rd magnetic patch (153) is close to the second magnetic patch (152), mutual repulsive force between the 3rd magnetic patch (153) and the second magnetic patch (152) and the first magnetic patch (151), weaken the magnetic attraction between the first magnetic patch (151) and the second magnetic patch (152), thereby first device and the second device are separated from each other.
6. one kind has the Biochemical Analyzer of magnetic block lock catch structure, comprise master control set (10) and proving installation (100), in master control set (10), be provided with storage chamber (15), proving installation (100) is housed in storage chamber (15), it is characterized in that: described magnetic block lock catch structure comprises at least three permanent magnet blocks, wherein the first magnetic patch (151) is fixed on proving installation (100), the second magnetic patch (152) is fixed on master control set (10), the 3rd magnetic patch (153) is placed on master control set (10) movably, when master control set (10) and electricity testing device (100) are during in mutually close position, three magnetic patch are arranged in straight line substantially, the second magnetic patch (152) is positioned between the first magnetic patch (151) and the 3rd magnetic patch (153), the two relative utmost point Magnetic Phases of the second magnetic patch (152) and the 3rd magnetic patch (153) are same, two utmost point magnetic that the first magnetic patch (151) is relative with the second magnetic patch (152) are different, the 3rd magnetic patch (153) can move along the line of three magnetic patch.
7. Biochemical Analyzer according to claim 6, is characterized in that: on master control set (10), be designed with two bracing frames (154), the 3rd magnetic patch (153) is connected with bracing frame (154) by spring leaf (155).
8. Biochemical Analyzer according to claim 6, is characterized in that: on master control set (10), be designed with two slide bars (156), the 3rd magnetic patch (153) can be by slide bar button (157) in the upper slip of slide bar (156).
9. Biochemical Analyzer according to claim 6, is characterized in that: on master control set (10), be designed with two springs (158), the 3rd magnetic patch (153) is conflicted mutually by snak link (159) and spring (158).
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| CN201210304384.7A CN102830067B (en) | 2011-09-21 | 2011-09-21 | Magnetic block lock structure, and using method and application thereof in biochemical analyzer |
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| CN201210304384.7A CN102830067B (en) | 2011-09-21 | 2011-09-21 | Magnetic block lock structure, and using method and application thereof in biochemical analyzer |
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| CN2011102817102A Division CN102374969A (en) | 2011-09-21 | 2011-09-21 | Magnetic block lock catch structure, using method thereof and application thereof to biochemical analyzer |
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| CN102830067A (en) | 2012-12-19 |
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