CN104237210A - Portable detection device - Google Patents
Portable detection device Download PDFInfo
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- CN104237210A CN104237210A CN201310228046.4A CN201310228046A CN104237210A CN 104237210 A CN104237210 A CN 104237210A CN 201310228046 A CN201310228046 A CN 201310228046A CN 104237210 A CN104237210 A CN 104237210A
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Abstract
The invention relates to a portable detection device, comprising a detection box, a detection chip, a smartphone and mobilephone software. When the portable detection device is in use, a to-be-detected sample is added on the detection chip; then the detection chip is inserted into the detection box; the smartphone is put in the device according to indication after a period of time; the mobilephone software is started for detection; and detection results are given out by the mobilephone software. The smartphone is a phone daily used by a user, so that only the mobilephone software is needed to install. The device is low in detection cost, fast in speed, easy to carry and convenient for operation. The device overcomes the defects of time consumption and high cost in detection of professional medical institutions, and is suitable for households, travel users, community hospitals, food detection institutions, etc.
Description
Technical field
This patent relates to a kind of pick-up unit, be specially a kind of based on smart mobile phone portable detector.
Background technology
Pathogenic bacteria comprise bacterium, virus, conveyor screw, rickettsia, Chlamydia, mycoplasma, fungi and actinomyces etc.
The mode of pathogenic microbes detect has immunization, nucleic acid method etc.Immunologic detection method has latex agglutination test (latex agglutination test, LA), immunogold staining (immunogold staining, IGS), time-resolved fluorescent immunoassay (time-resolved fluoro-immunoassay, TR-IFMA) etc., nucleic acid detection method has PCR (polymerase chain reaction, PCR), strand displacement amplification reaction (strand displacement amplification, SDA), ligase chain reaction (ligase chain reaction, LCR), rely on amplified reaction (the nucleic acid sequence-based amplification of nucleotide sequence, NASBA), amplified reaction (the transcription-mediated amplification of transcriptive intermediate, TMA), loop-mediated isothermal amplification (loop-mediated isothermal amplification, LAMP), rolling circle amplification reaction (rolling circle amplification, RCA), rely on unwindase isothermal amplification (helicase-dependent amplification, HDA).
At present, immunization and nucleic acid method are all detected by optical signalling, and common optical detection apparatus volume is large, expensive, complex operation, and this causes pathogenic microbes detect can only carry out in the professional institutions such as hospital.If when needing to detect suspected infection patient or the doubtful food containing pathogenic bacteria, patient or user can only send sample, cannot detect voluntarily.
On the one hand, testing cost is which increased; On the other hand, because testing lag causes follow-up diagnosis, treats and also cannot carry out in time, when particularly breaking out extensive epidemic situation, effective control of epidemic situation cannot be accomplished.
The smart mobile phone of current built-in high sensitivity, high resolution CCD/cmos cell is very universal, utilizes the optical module of smart mobile phone can lower equipment cost greatly, can also lower user and use difficulty.In addition, smart mobile phone also has mobile interchange function, and testing result can interconnect in associated mechanisms such as governments, forms a network monitoring system.
Summary of the invention
This patent technical matters to be solved is, overcomes the inconvenience of traditional pathogenic microbes detect flow process, cycle long, high in cost of production defect, provide a kind of small and exquisite portable, quickly and accurately, cost is low, the pick-up unit that is applicable to family and suitable to individual.
This patent solves the problems of the technologies described above adopted technical scheme: a kind of based on smart mobile phone portable detector, comprise and detect box, detection chip, smart mobile phone, cell phone software.
Described detection box is for controlling detection chip temperature of reaction, fixing mobile phone, providing and detect optical system used, and circuit board is placed in inside.
Described detection chip is the micro-fluidic chip having fluid channel and micro reaction pool in, has sample filling orifice, and after adding sample, the detection box described in insertion, carries out subsequent reactions.
Described smart mobile phone is the mobile phone with operating system, and operating system comprises but do not limit Symbian, iOS, Android, MeeGo, Windows phone, and described smart mobile phone is the general mobile phone that market is sold, and user can buy voluntarily.
Described cell phone software is a software, and the smart mobile phone of user runs.Process the light signal collected, output detections result, cell phone software also can realize testing result and manage, provides diagnosis scheme, interconnection network acquisition relevent information, uploads data to the functions such as server
Described detection box comprises temperature control module, optical module, appurtenances.Temperature control module having heaters part, thermal insulation board, heat-conducting plate, temperature sensor, circuit board, battery; Optical module has pack-shot lens, illuminating lamp, chip groove; Accessory module has housing, button, pilot lamp, expansion mobile phone supporting plate.
Described button is arranged on described housing, for controlling the operation of described detection box, described pilot lamp is arranged on described housing, be connected with circuit board, for showing the running status of described detection box, described expansion mobile phone supporting plate is arranged on described housing side, can rotary moveable, can as upper cover in folding state of packing up, at the supporting plate of the state launched as mobile phone, described pack-shot lens is arranged on described housing, for the Nonlinear magnify on described chip is taken for mobile phone, described illuminating lamp is arranged on described enclosure interior, and be connected with circuit board, for described chip is thrown light on, described chip groove is arranged on described enclosure interior, for giving described chip positioning, described heater element is arranged on described enclosure interior, be connected with circuit board, for giving described chip heating, described thermal insulation board is arranged on described enclosure interior, for the thermal diffusion of isolated described heater element, described heat-conducting plate is arranged on described enclosure interior, for the even heat of described heater element is conducted to described chip, described temperature sensor is arranged on described heat-conducting plate, be connected with described circuit board, for detected temperatures, described circuit board is arranged on described enclosure interior, for supporting and the operation of detection box described in controlling, described battery is arranged on described enclosure interior, for power supply.
In another scheme, described pick-up unit also comprises power supply adaptor, and power supply adaptor is used for powering to described detection box.
Described power supply adaptor is used for the low-voltage DC become by the voltage that 220V voltage or vehicle, miscellaneous equipment provide for described detection box.
Compared with prior art, the advantage of this patent with a set of small and exquisite moveable, at a low price, system easy to use realizes pathogenic microbes detect, due to highly integrated and microminiaturized, so use simple, be easy to carry, just can produce in enormous quantities by existing production technology, so production cost is low, and reliability is high, is very suitable for family, individual, community hospital, travelling merchants client etc. and uses.
accompanying drawing explanation
Fig. 1 is the system composition schematic diagram of this patent.
Fig. 2 is the detection box folded state schematic diagram of this patent.
Fig. 3 is the detection box deployed condition front-view schematic diagram of this patent.
Fig. 4 is the detection box deployed condition schematic rear view of this patent.
Fig. 5 is the system composition diagrammatic cross-section of this patent.
Fig. 6 is the composition schematic diagram of the circuit board of this patent, illuminating lamp, chip draw-in groove.
Fig. 7 is the chip structure schematic diagram of this patent.
embodiment
Below in conjunction with accompanying drawing embodiment, this patent is described in further detail.
As shown in Figure 1, a kind of based on smart mobile phone portable detector, it comprise detect box (10), chip (30), smart mobile phone (40), cell phone software.Detect time, put mobile phone with the use of.As shown in Figure 2, when not using, detecting box (10) collapsible, being easy to carry and protecting the part of the inside.During concrete use, sample to be detected is added chip (30), as shown in Figure 7, chip (30) has micro reaction pool (31) and fluid channel (32), sample liquid can be transported to micro reaction pool (31) by fluid channel (32).Then chip is inserted and detect box (10), box (10) will be detected be energized and start, prompting step according to pilot lamp and cell phone software operates, through after a period of time, operating handset software carries out interpretation to the result in chip, provide testing result, the diagnostic function of cell phone software can also be used, networking such as to obtain information at the function.
As shown in Figure 3 and Figure 5, detect box (10) and comprise housing (11), button (12), pilot lamp (13), expansion mobile phone supporting plate (14), web joint (9), pack-shot lens (15), illuminating lamp (16), chip groove (17), heater element (18), thermal insulation board (19), heat-conducting plate (20), temperature sensor (21), circuit board (22), battery (23).The start-up and operation of device is controlled by button (12), and the stage of detection and the running status of equipment can be differentiated by pilot lamp (13).As shown in Figure 3, first expansion mobile phone supporting plate (14) is opened during use, and be put in smooth desktop, then mobile phone is placed on supporting plate, housing (11) and expansion mobile phone supporting plate (14) can ensure that the camera of mobile phone aims at pack-shot lens (15), illuminating lamp (16) can provide enough illuminations, and such mobile phone just can photograph the picture rich in detail of the upper micro reaction pool (31) of chip (30).As shown in Figure 6, chip groove (17) provides the effect of guiding and location to chip (30), and can ensure that the micro reaction pool (31) of chip (30) can aim at pack-shot lens (15).
The temperature of the real-time reading temperature sensor (21) of circuit board (22), by the heating process of the microprocessor controls heater element (18) on circuit board (22), makes heat-conducting plate (20) and micro reaction pool (31) region reach the temperature of setting.Heat-conducting plate (20) plays the effect even heat of heater element (18) being conducted to chip, and thermal insulation board (19) then plays insulation, heat insulation effect.
Power supply during use depends on internal battery (23), and when internal battery electricity exhausts, power supply adaptor also can be used external power source to be transferred to low-voltage DC and power for detecting box, battery (23) also can be charged simultaneously.As shown in Figure 4, detect box (10) rear portion and have supply hub.
Claims (6)
1. a portable detector, comprise smart mobile phone, cell phone software, it is characterized in that: described portable detector also comprises detection box, detection chip, described detection chip is inserted in described detection box, described smart mobile phone obtains optical signalling, and according to optical signalling, cell phone software provides testing result.
2. portable detector as claimed in claim 1, is characterized in that: described detection box comprises temperature control module, for controlling the temperature of reaction in described detection chip.
3. portable detector as claimed in claim 1, is characterized in that: described detection box comprises micro-lens, for the optical signalling by detection chip described in described smart mobile phone Obtaining Accurate.
4. portable detector as claimed in claim 1, it is characterized in that: described detection box comprises expansion mobile phone supporting plate, described expansion mobile phone supporting plate can rotary moveable, can as the upper cover of described detection box in folding state of packing up, in the state launched as the supporting plate of mobile phone, the camera of mobile phone and micro-lens are accurately located.
5. portable detector as claimed in claim 1, is characterized in that: described detection chip be comprise fluid channel, micro reaction pool, sample add hand-hole.
6. portable detector as claimed in claim 1, is characterized in that: described portable detector is used for immune detection, detection of nucleic acids, cell detection (comprising cell count, bacterial classification identification etc.), biochemistry detection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310228046.4A CN104237210A (en) | 2013-06-08 | 2013-06-08 | Portable detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310228046.4A CN104237210A (en) | 2013-06-08 | 2013-06-08 | Portable detection device |
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| Publication Number | Publication Date |
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| CN104237210A true CN104237210A (en) | 2014-12-24 |
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| CN201310228046.4A Pending CN104237210A (en) | 2013-06-08 | 2013-06-08 | Portable detection device |
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Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104778964A (en) * | 2015-04-03 | 2015-07-15 | 程志 | Detection USB flash disk for disease diagnosis |
| CN104897556A (en) * | 2015-05-29 | 2015-09-09 | 河北工业大学 | Milk somatic cell counting device and method based on intelligent terminal and micro-fluidic chip |
| CN105925476A (en) * | 2016-04-23 | 2016-09-07 | 北京化工大学 | Portable isothermal nucleic acid analysis device based on mobile phone detection |
| CN106148177A (en) * | 2015-03-27 | 2016-11-23 | 中国科学院青岛生物能源与过程研究所 | A kind of quick count plate system based on micro flow chip and smart mobile phone |
| CN106680276A (en) * | 2016-12-28 | 2017-05-17 | 宁波大学 | Biochip detector |
| CN106680439A (en) * | 2015-11-09 | 2017-05-17 | 北京艾旗斯德科技有限公司 | Miniature food safety and in-vitro diagnosis analyzer |
| CN106680471A (en) * | 2016-12-28 | 2017-05-17 | 宁波大学 | Biochip detection system |
| CN106706590A (en) * | 2017-02-16 | 2017-05-24 | 韶关市食品药品检验所 | Portable fluorescence chip data collector |
| CN106846644A (en) * | 2017-01-07 | 2017-06-13 | 孙翠敏 | A kind of self-service tumor markers colony intelligence detection means and method |
| CN107613162A (en) * | 2017-08-11 | 2018-01-19 | 浙江大学 | A kind of portable micro-fluidic chip imaging system |
| CN108124088A (en) * | 2017-12-22 | 2018-06-05 | 广安长明高端产业技术研究院 | The method of micro-fluidic chip camera arrangement and shooting micro-fluidic chip based on smart mobile phone and simple light pipe |
| CN108614100A (en) * | 2018-07-19 | 2018-10-02 | 苏州芯海智能科技有限公司 | A kind of quickly and easily detection device |
| CN108646012A (en) * | 2018-07-20 | 2018-10-12 | 苏州芯海智能科技有限公司 | A kind of paper chip quickly detected |
| CN108922584A (en) * | 2018-08-28 | 2018-11-30 | 深圳先进技术研究院 | Convenient and quick detection device and its application |
| CN110940645A (en) * | 2019-10-29 | 2020-03-31 | 浙江大学 | Portable fluorescence sensing platform for cadmium ion detection and detection method |
| CN111551544A (en) * | 2020-05-06 | 2020-08-18 | 东南大学 | Bivalent copper ion rapid detection device and detection method based on paper-based micro-fluidic chip |
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2013
- 2013-06-08 CN CN201310228046.4A patent/CN104237210A/en active Pending
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| CN106148177A (en) * | 2015-03-27 | 2016-11-23 | 中国科学院青岛生物能源与过程研究所 | A kind of quick count plate system based on micro flow chip and smart mobile phone |
| CN104778964A (en) * | 2015-04-03 | 2015-07-15 | 程志 | Detection USB flash disk for disease diagnosis |
| CN104897556A (en) * | 2015-05-29 | 2015-09-09 | 河北工业大学 | Milk somatic cell counting device and method based on intelligent terminal and micro-fluidic chip |
| CN106680439A (en) * | 2015-11-09 | 2017-05-17 | 北京艾旗斯德科技有限公司 | Miniature food safety and in-vitro diagnosis analyzer |
| CN105925476A (en) * | 2016-04-23 | 2016-09-07 | 北京化工大学 | Portable isothermal nucleic acid analysis device based on mobile phone detection |
| CN106680471B (en) * | 2016-12-28 | 2018-09-28 | 宁波大学 | A kind of biological chips detection system |
| CN106680276A (en) * | 2016-12-28 | 2017-05-17 | 宁波大学 | Biochip detector |
| CN106680471A (en) * | 2016-12-28 | 2017-05-17 | 宁波大学 | Biochip detection system |
| CN106680276B (en) * | 2016-12-28 | 2024-04-09 | 浙江正合谷生物科技有限公司 | Biochip detector |
| CN106846644B (en) * | 2017-01-07 | 2019-06-07 | 孙翠敏 | A kind of self-service tumor markers colony intelligence detection device and method |
| CN106846644A (en) * | 2017-01-07 | 2017-06-13 | 孙翠敏 | A kind of self-service tumor markers colony intelligence detection means and method |
| CN106706590A (en) * | 2017-02-16 | 2017-05-24 | 韶关市食品药品检验所 | Portable fluorescence chip data collector |
| CN107613162A (en) * | 2017-08-11 | 2018-01-19 | 浙江大学 | A kind of portable micro-fluidic chip imaging system |
| CN107613162B (en) * | 2017-08-11 | 2020-11-20 | 浙江大学 | Portable micro-fluidic chip imaging system |
| CN108124088A (en) * | 2017-12-22 | 2018-06-05 | 广安长明高端产业技术研究院 | The method of micro-fluidic chip camera arrangement and shooting micro-fluidic chip based on smart mobile phone and simple light pipe |
| CN108614100A (en) * | 2018-07-19 | 2018-10-02 | 苏州芯海智能科技有限公司 | A kind of quickly and easily detection device |
| CN108646012A (en) * | 2018-07-20 | 2018-10-12 | 苏州芯海智能科技有限公司 | A kind of paper chip quickly detected |
| CN108922584A (en) * | 2018-08-28 | 2018-11-30 | 深圳先进技术研究院 | Convenient and quick detection device and its application |
| CN110940645A (en) * | 2019-10-29 | 2020-03-31 | 浙江大学 | Portable fluorescence sensing platform for cadmium ion detection and detection method |
| CN110940645B (en) * | 2019-10-29 | 2021-10-19 | 浙江大学 | Portable fluorescence sensing platform for cadmium ion detection and detection method |
| CN111551544A (en) * | 2020-05-06 | 2020-08-18 | 东南大学 | Bivalent copper ion rapid detection device and detection method based on paper-based micro-fluidic chip |
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Application publication date: 20141224 |