CN106680471B - A kind of biological chips detection system - Google Patents
A kind of biological chips detection system Download PDFInfo
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- CN106680471B CN106680471B CN201611234353.3A CN201611234353A CN106680471B CN 106680471 B CN106680471 B CN 106680471B CN 201611234353 A CN201611234353 A CN 201611234353A CN 106680471 B CN106680471 B CN 106680471B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
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Abstract
The invention discloses a kind of biological chips detection systems, enriching apparatus including bio-chip test device and for biological specimen collection, feature is that bio-chip test device includes holder, image capturing mechanism, biochip loader mechanism and light source mechanism are provided on holder, image capturing mechanism is arranged before biochip loader mechanism, and light source mechanism is arranged after biochip loader mechanism；Enriching apparatus includes enrichment box, and enrichment box is removably disposed on holder, is enriched in box and is provided with object placing cavity, and the interior storage of object placing cavity is provided with hybridizing reagent, hybridizing box and biochip.Advantage is to be removably disposed in holder for the enrichment box of biological sample collection, and it is provided with object placing cavity in enrichment box, it is placed in object placing cavity and detects relevant hybridizing reagent, hybridizing box and biochip, each equipment of detection is combined, it is neat and small, it is easy to remove, it is simple in structure, it is easy to use.
Description
Technical field
The present invention relates to biochip test fields, more particularly, to a kind of biological chips detection system.
Background technology
Biochip (biochip or bioarray) be according to the principle specifically to interact between biomolecule, will be biochemical
Analytic process is integrated in chip surface, to realize the high throughput to DNA, RNA, polypeptide, protein and other biological ingredient
Quickly detection.The biochip concept of narrow sense refers to by distinct methods by biomolecule (oligonucleotides, cDNA, genomic
DNA, polypeptide, antibody, antigen etc.) it is bonded in the solid phase mediators such as silicon chip, sheet glass (pearl), plastic sheet (pearl), gel, nylon membrane
The biomolecule dot matrix of formation.The concept of chip takes from integrated concept, and biochip is the integrated of biomaterial.As experiment
Room detection is the same, and blood glucose, albumen, enzymatic activity etc. are checked on biochip, is to be based on same biological respinse principle.So raw
Object chip is exactly a carrier platform, is a carrier, is that discontinuous analytic process in life science is integrated in base
The miniature biochemical analysis system on piece surface, to realize to the accurate, fast of cell, protein, gene and other biological components
The detection of speed, large information capacity.The technical advantage that biochip has keeps detection quicker, sensitive and accurate.Conventional biology
Chip detection needs to use the equipment such as nucleic acid augmentative instrument, chip hybridization instrument, chip cleaner and detector.Currently on the market upper
It is not only expensive to state a whole set of related equipment, and volume is big and heavy, should not often move, and mobile difficult larger.
Invention content
Technical problem to be solved by the invention is to provide a kind of small and easy to remove biological chips detection systems.
Technical solution is used by the present invention solves above-mentioned technical problem：
A kind of biological chips detection system, including bio-chip test device and the enrichment for biological specimen collection fill
It sets, the bio-chip test device includes holder, image capturing mechanism is provided on the holder, biochip loads
Mechanism and light source mechanism, the image capturing mechanism are arranged before the biochip loader mechanism, the light source
Mechanism is arranged after the biochip loader mechanism；The enriching apparatus includes enrichment box, and the enrichment box can
Releasably it is arranged on the holder, object placing cavity is provided in the enrichment box, stores and is provided in the object placing cavity
Hybridizing reagent, hybridizing box and biochip.
The holder include shelved on vertically arranged plate and under shelve plate, it is described on shelve plate can up and down adjustment
The top that plate is shelved under described is set, it is described on shelve the front end face of plate with it is described under shelve plate front end face it is neat
It is flat, it is described on shelve the both sides of plate and be respectively arranged with the upper side shield extended forward, the both sides difference of plate is shelved under described
Being extended forward has a lower side shield, the upper side shield and the downside baffle position up and down with respect to and the upside
The inner side end of baffle is flushed with the inner side end of the lower side shield, and the lower part that plate is shelved under described is extended forward
Have a lateral lower positioning plate, the upper side shield, lower side shield, on shelve plate, under shelve plate and the lower positioning plate it
Between enclose and be set as one and shelve chamber.Above-mentioned supporting structure is simple, easily manufactured, above shelves plate and can be arranged to up and down adjustment and is shelved under
On plate so that the holder can be adapted to the mobile phone of different length, and lower positioning plate plays the role of lower positioning to mobile phone, ensures mobile phone
It can steadily be seated on holder.
It is provided with the first vertical guide chute in the upper side shield, downslide can be gone up in first guide chute
It is provided with the first guide post dynamicly, height regulating rod is connected with below first guide post, the upper side shield
Lower face is provided with height adjusting holes, and the vertical centerline of the height adjusting holes is vertical with first guide chute
Center line coincides, and the height adjusting holes are connected with first guide chute, the height regulating rod
Lower part is stretched out the height adjusting holes and is fixed on the lower side shield.It is led by the first guide chute and first
Cooperation to column play the guiding role to the movement of height regulating rod.
The internal diameter of the height adjusting holes is more than the outer diameter of the height regulating rod and is oriented to less than described first
The outer diameter of column.The internal diameter of height adjusting holes is more than outer diameter of the outer diameter less than the first guide post of height regulating rod, ensures that height is adjusted
Pole can be swimmingly up and down and can be stably mounted to shelve on plate.
The front end face of the upper side shield is provided with internal thread hole, and the internal thread hole is oriented to described first and slides
Slot is connected, and lock-screw is bolted on the internal thread hole, by lock-screw by the position of the height regulating rod
It is locked.The front end face of upper side shield is provided with internal thread hole, and lock-screw is bolted in internal thread hole, above shelves the height of plate
After the completion of degree is adjusted, the position of height regulating rod is fixed by tightening lock-screw.
The image capturing mechanism includes the mobile phone with camera function and image capture plate, and the mobile phone is shelved on institute
That states shelves intracavitary, it is described on shelve and be provided with the front and back image capture window penetrated through on plate, the image capture plate can
Slidingly be arranged on the image capture window, the front end face of the image capture plate with it is described under shelve plate
Front end face flush, the front and back image capture hole penetrated through is provided on the image capture plate, the biochip loads
Mechanism is located at the rear in the image capture hole.Above-mentioned image capturing mechanism is simple in structure, easy to operate, is shelved on plate upper
The front and back image capture window penetrated through is set, one can slidingly be arranged on image capture window and carry image capture hole
Image capture plate is adapted to camera by the position of left and right adjusting image capture plate and the mobile phone in different location is arranged, specifically makes
Mobile phone is set to be shelved on and shelves intracavitary by the used time, adjust image capture plate left and right position and on shelve the upper and lower position of plate, make
Camera on mobile phone can be directed at image capture hole, and the lower part of mobile phone can stablize and be shelved on lower positioning plate, then lead to
Cross the biological information on the biochip loaded on the capture biochip loader mechanism of the mobile phone with camera function.
Two inner faces up and down of the image capture window are provided with to be matched with the image capture plate thickness
Sliding slot, the image capture plate is slidably disposed in the sliding slot, it is described on shelve the upper surface setting of plate
There is vertical locking hole, the locking hole is connected with the sliding slot on the image capture window upper interior end face, described
Locking hole on be bolted with a lock-screw, the position of the image capture plate is fixed by the lock-screw.
By realizing horizontally slipping for image capture plate with the matched sliding slot of image capture plate thickness, different camera positions can be adapted to
Mobile phone, it is simple in structure, it is easy to operate.
The clamp system being provided on plate for mobile phone to be fixedly clamped is shelved under described, the clamp system includes
Width adjusting bar and clamping plate, it is described on shelve the front end face of plate and be provided with the groove being recessed backward, shelve plate under described
It is inside provided with the second lateral guide chute, the second guide post can be slidingly provided in second guide chute,
It is provided with lateral resetting spring, the groove between second guide post and the second guide chute side end face
Side end face on be provided with width adjusting hole, the cross central line in the width adjusting hole and second guide chute
Cross central line overlaps, and the width adjusting hole is connected with second guide chute, the width adjusting bar
One end stretches into the width adjusting hole and is connected with second guide post, and the clamping plate is fixed at described
The other end of width adjusting bar.When above-mentioned clamp system mobile phone be shelved on to shelve intracavitary, left and right position can also obtain standard
It determines position, guiding role is played to the movement of width adjusting bar by the second guide chute and the second guide post, resetting spring is given
One tightening force of clamping plate, it is simple in structure, it is easy to operate, and clamp and stablize.
The internal diameter in the width adjusting hole is more than the outer diameter of the width adjusting bar and is oriented to less than described second
The outer diameter of column.The internal diameter in width adjusting hole is more than the outer diameter of width adjusting bar and the outer diameter less than the second guide post so that width
Adjusting rod can swimmingly horizontally slip and have there are one stablize positioning.
It pulls out with the clamping plate and is provided with and the clamping plate on the consistent lower side shield in direction
Matched opening is provided with protection with the inner face of the clamping plate lower side shield that pull out direction opposite
Pad.It is open pulling out to be arranged on the consistent lower side shield in direction with clamping plate, which facilitates the operation of clamp system,
And neonychium is being set with the inner face of the clamping plate lower side shield that pull out direction opposite, the neonychium is then to the side of mobile phone
Portion shields.
The biochip loader mechanism includes load frame and load frame mounting base, is set in the load frame
It is equipped with the front and back rectangular watch window penetrated through, is vertically provided in the load frame and biochip matched the
One slot, biochip insertion is arranged in first slot and the detection sample position on the biochip
In in the watch window；The front and back cylindric inner cavity penetrated through, the dress are provided in the load frame mounting base
Carry frame mounting base on be provided with up and down with matched second slot of load frame, the load frame
Insertion is arranged in second slot；The load frame mounting base is mounted on the rear end face of the image capture plate
On, the cylindric inner cavity and the image capture hole are coaxial, the image capture hole and the cylindric inner cavity
Between be provided with lens.Load frame is simple in structure, and the first slot is provided for making biochip be inserted into it to biochip
One stable installation positioning, watch window is convenient for observation；The second slot being arranged in load frame mounting base is filled for being inserted into
Frame is carried, cylindric inner cavity and image capture hole are coaxial, it is ensured that can be on accurate observation to biochip by image capture hole
Biological information, lens are set between image capture hole and cylindric inner cavity, are believed the biology on biochip by lens
Breath amplification, more clear biometric image can be captured convenient for mobile phone.
The front end face of the load frame mounting base is provided with the cylindric installation cavity for mounted lens, described
Installation cavity is with the cylindric coaxial and the internal diameter of the installation cavity is more than the cylindric inner cavity
Internal diameter, the size of the lens and the matching size of the installation cavity close.The installation being arranged in load frame mounting base
Cavity is for giving lens to provide a stable installation positioning, installation cavity and cylindric coaxial so that lens can be compared with
The effect for playing the biological information on amplification biochip well, the internal diameter for installing cavity are more than the internal diameter of cylindric inner cavity, thoroughly
The size of mirror and the matching size of installation cavity close so that lens can be stably mounted in installation cavity, and lens is avoided to fall into
To influencing normal use in cylindric inner cavity.
The position adjusting mechanism for adjusting load frame upper and lower position is provided in the load frame mounting base.It is logical
It crosses position adjusting mechanism and adjusts upper and lower position of the load frame in load frame mounting base, so that the life on biochip
Object information can be captured completely.
The position adjusting mechanism includes mutually matched adjusting internal gear and adjusting external gear, the load frame
Mounting base includes the columned preceding pedestal of coaxial arrangement and rear pedestal, and the outer diameter of the preceding pedestal is more than the rear pedestal
Outer diameter, second slot is arranged on the preceding pedestal, and the side of the load frame mounting base is circumferentially equal
Cloth is provided at least two recessed portions, and the recessed portion is connected with the cylindric inner cavity, the adjusting external gear
It is rotatably arranged in the recessed portion, two lateral surfaces of the load frame are provided with and the adjusting external tooth
Matched rack is taken turns, the adjusting inner gear housing is located on the rear pedestal and is mutually nibbled with the adjusting external gear
It closes, load frame insertion is arranged in second slot and the rack is mutually nibbled with the adjusting external gear
It closes, the rear portion of the rear pedestal is coaxially disposed restraining position ring block.Above-mentioned position adjusting mechanism, simple in structure, easy to operate, rear base
Seat is used for installation and adjustment external gear, and a front limit and rear limit are provided to the installation for adjusting internal gear by preceding pedestal and spacing ring
Position, it is ensured that adjust internal gear stablizes installation, when adjusting rotation adjust internal gear, drive the adjusting external tooth rotation being meshed therewith
It is dynamic, drive the rack being meshed with the adjusting external gear to move up and down, so that load frame is transported up and down along the second slot
It is dynamic, realize that the upper and lower position of load frame is adjusted.
The side of the rear pedestal is provided with the third slot of perforation, and astigmatism is inserted in the third slot
Piece.Be inserted into scattering sheet in third slot, the equalizing light rays that light source mechanism can be emitted, convenient for biochip into
Row is clearly viewed.
The outer diameter of the spacing ring is more than the outer diameter of the rear pedestal.The outer diameter of spacing ring is more than the outer of rear pedestal
Diameter, it is ensured that spacing ring plays stable rear position-limiting action.
It is uniformly arranged anti-slop serrations on the lateral wall of the adjusting internal gear.The setting of anti-slop serrations can increase adjusting internal tooth
The frictional force for taking turns lateral wall, convenient for carrying out rotation operation to it.
The light source mechanism includes light source, driving power, light source mounting base and driving power mounting base, the light source
Mounting base is fixedly mounted on the rear end of the spacing ring, be provided in the light source mounting base it is front and back penetrating through and with it is described
Cylindric coaxial light transmission chamber, the light source is mounted on the light transmission intracavitary, and the rear end of the light source is arranged
There are the power supply conduction panel being electrically connected with the light source, the driving power to be mounted in the driving power mounting base,
The driving power mounting base is arranged is provided with triggering on the rear of the light source mounting base, the driving power
Plate, the power supply conduction panel described in the trigger board face, the electricity when the trigger board and the power supply conduction panel contact
Source conducting makes the light source luminescent.Above-mentioned light source mechanism is simple in structure, passes through light source mounting base and driving power mounting base point
Not Gei light source and driving power one stable installation space is provided, by separation between power supply conduction panel and trigger board and connect
The closing for realizing light source and opening are touched, it is easy to operate, it is easy to use.
The rear end of the light source mounting base is provided with externally threaded mounting ring, under unused state, the driving
In the mounting ring, the trigger board is separated power supply mounting base screwing sections with the power supply conduction panel, uses
When, screwing the driving power mounting base makes the trigger board be in contact with the power supply conduction panel, the light source
It shines.Driving power mounting base can not only be stably mounted in light source mounting base by above structure, while can fast implement electricity
It separation between source conduction panel and trigger board and contacts, it is simple in structure, it is easy to operate.
The outside portion of the driving power mounting base has been uniformly arranged anti-slop serrations.The setting of anti-slop serrations can increase driving electricity
The frictional force of source mounting base lateral wall, convenient for carrying out rotation operation to it.
The lower side shield, which extends back, is provided with adjutage.Adjutage plays a supporting role to entire holder.
The support leg for being used to support the holder is provided on the adjutage.Support leg is provided on adjutage
Further function as the supporting role to entire holder so that entire holder is stabilized support.
The support leg support angle is adjustable and can move up and down along the adjutage.Support leg adjustable angle and can
It moves up and down along adjutage so that the support angle of holder is adjustable, convenient for being operated to the mobile phone being shelved on holder.
The enriching apparatus further includes enrichment test tube, and the enrichment box includes bottom plate, top plate, backboard and two sides
Plate, floor level setting, the side plate described in two are vertically provided at the both sides of the bottom plate, the backboard respectively
It is vertically provided on the bottom plate and the both sides of the backboard is connected with the side plate described in two respectively, the top plate
Both sides can be arranged to pull on the inner side end of the side plate described in two respectively, the bottom plate, top plate, backboard and two
The cavity for being set as a front opening is enclosed between side plate, and one is horizontally arranged in the cavity and shelves plate, described shelves plate
Both sides be connected respectively with the side plate described in two, described shelving is vertically arranged by one between plate and the bottom plate
Support plate is connected, described shelving be provided on plate it is multiple it is matched with the described enrichment test tube shelve through-hole, it is described
Enrichment test tube be shelved on it is described shelve in through-hole, immunomagnetic beads are provided in the enrichment test tube, in the support plate
It is provided with magnet.The enriching apparatus is simple in structure, easy to operate, and an enrichment frame is constituted by shelving plate, support plate and bottom plate,
Magnet is set in support plate, is enriched on frame and shelves the enrichment test tube with immunomagnetic beads, when use, which pours into Biosample, to be equipped with
It in the enrichment test tube of immunomagnetic beads, is adsorbed by immunomagnetic beads with the biology that the immunomagnetic beads match, then biology examination will be housed
The enrichment test tube of sample is shelved on enrichment frame, is adsorbed onto the immunomagnetic beads for being adsorbed with detection biology by the magnet in support plate
On test tube wall, then the entire enrichment box of operation pours out remaining Biosample, just can effectively be enriched to the life for needing to detect
Object sample；The cavity for being set as a front opening, the setting of the opening are enclosed additionally by bottom plate, top plate, backboard and two side plates
It is observed convenient for the enrichment condition to biological sample；The inner side end in two side plates can be arranged to pull in top plate both sides respectively
On, the position of top plate is adjusted by draw operation, picking and placeing and operating convenient for enrichment test tube.
The support plate is arranged is divided into noseplate and rear bottom in the centre position of the cavity by the bottom plate
The both sides of plate, the support plate are connected with the side plate described in two respectively, and the plate of shelving is located at the noseplate
Top, enclosed between the rear bottom plate, support plate, backboard and two side plates and be set as the object placing cavity, the noseplate,
It shelves to enclose between plate, support plate and two side plates and is set as an enrichment chamber.Support plate is arranged in the centre position of cavity so that empty
Chamber is divided into object placing cavity and enrichment chamber two chambers, and object placing cavity can be used for putting and the relevant article of biological specimen collection, such as
Glass slide, sampling reagent etc. so that the enriching apparatus is provided simultaneously with function of containing articles, vdiverse in function.
The enrichment intracavitary is vertically uniformly arranged at intervals with multiple partition boards, is formed between the partition board described in adjacent two
One independent enrichment room, is correspondingly arranged that there are one described to shelve through-hole on the enrichment room, it is each described in richness
Collection interior is provided with one and shelves seat, and the seat of shelving is fixed on the noseplate, and described shelving is arranged on seat
Cavity is shelved, the cavity of shelving is located at the underface for shelving through-hole.Chamber will be entirely enriched with by partition board to separate
At multiple independent enrichment rooms, each room that is enriched with can carry out independent enrichment procedure, convenient for observation and distinguish.Shelve the setting of seat
So that shelving for enrichment test tube is more stablized, the bottom for being enriched with test tube is shelved on and shelves in cavity, avoids when enrichment box is by outer
It is enriched with test tube double swerve when force effect, to influence concentration effect, and shelves cavity and is located at the underface for shelving through-hole, ensure
Shelving vertically to shelve for enrichment test tube, ensures concentration effect.
Magnet insertion is arranged in the inside of support plate, avoids magnet from being chronically exposed in air and chemical reaction influence suction occurs
Attached effect.
The upper interior end face of side plate described in two is provided with and the matched sliding slot of the top plate thickness, the top
The both sides of plate are slidably disposed in the sliding slot.By sliding slot realize top plate front and back pull, be convenient for enrichment and
The operation of article is picked and placeed, it is simple in structure, it is easy to operate.
Described shelving is provided with vertical baffle on plate.The baffle is for preventing the object in object placing cavity from dropping out.
The tread plate to raise up is provided on the top plate.Tread plate is convenient for operating the pull of top plate with hand.
The arrow for being used to indicate pull direction is provided on the top plate.Arrow is used to indicate the pumping of top plate
Direction is drawn, maloperation is avoided.
Vertical installation sliding slot is provided on side plate described in two, the rear end face that plate is shelved under described is relatively set with
Two support arms, be provided on the inner face of the support arm described in two with the matched installation sliding block of the installation sliding slot,
The installation sliding slot realizes the disassembly and installation of the enrichment box with the cooperation for installing sliding block.By installing sliding slot and installation
The disassembly and installation of enrichment box is realized in the cooperation of sliding block, simple in structure, easy to operate.
Compared with the prior art, the advantages of the present invention are as follows：Enrichment box for biological sample collection is removably disposed
It on holder, and is enriched in box and is provided with object placing cavity, placed in object placing cavity and detect relevant hybridizing reagent, hybridizing box and biology
Chip combines each equipment of detection, neat and small, easy to remove, simple in structure, easy to use.
Description of the drawings
Fig. 1 is the overall structure diagram of bio-chip test device in the present invention；
Fig. 2 is the structural schematic diagram of holder in the present invention；
Fig. 3 is the structural schematic diagram that Fig. 2 removes width adjusting bar and clamping plate；
Fig. 4 is DOCK LEVELER and the matched schematic cross-sectional view of upper side shield in the present invention；
Fig. 5 be in the present invention under shelve the schematic cross-sectional view of plate；
Fig. 6 is the configuration schematic diagram that bio-chip test device removes holder and mobile phone in the present invention；
Fig. 7 is the schematic cross-sectional view that bio-chip test device removes holder and mobile phone in the present invention；
Fig. 8 is the structural schematic diagram that test tube is enriched in the present invention；
Fig. 9 is the structural schematic diagram that box is enriched in the present invention；
Figure 10 is the structural schematic diagram that enrichment box removes top plate in the present invention；
Figure 11 is the present invention looks up structural representation of bio-chip test device in the present invention；
Figure 12 is that enrichment box is installed to the structural schematic diagram on holder in the present invention.
Specific implementation mode
Below in conjunction with attached drawing embodiment, present invention is further described in detail.
Embodiment one：As shown in Figures 1 to 12, a kind of biological chips detection system, including bio-chip test device and
For the enriching apparatus of biological specimen collection, bio-chip test device includes holder A, and image capture machine is provided on holder A
Structure B, biochip loader mechanism C and light source mechanism D, image capturing mechanism B are arranged before biochip loader mechanism C, light
Source mechanism D is arranged after biochip loader mechanism C；Enriching apparatus includes enrichment box H, and enrichment box H is removably disposed in
It on holder A, is enriched in box H and is provided with object placing cavity H5, stored in object placing cavity H5 and be provided with hybridizing reagent (not shown), hybridization
Box (not shown) and biochip G.
In this particular embodiment, holder A include shelved on vertically arranged plate A1 and under shelve plate A2, above shelve plate
The top that plate A2 is shelved under can be arranged to up and down adjustment in A1, above shelve plate A1 front end face shelved under plate A2 front end face it is neat
Flat, the both sides for above shelving plate A1 are respectively arranged with the upper side shield A11 extended forward, under shelve the both sides of plate A2 and respectively forwardly prolong
Stretch and be provided with lower side shield A21, upper side shield A11 and the lower positions side shield A21 up and down with respect to and upper side shield A11 inside
End face is flushed with the inner side end of lower side shield A21, under shelve the lower part of plate A2 and be extended forward and have lateral lower positioning plate
A22, upper side shield A11, lower side shield A21, on shelve plate A1, under shelve to enclose between plate A2 and lower positioning plate A22 and be set as one
Shelve chamber E.Above-mentioned supporting structure is simple, easily manufactured, above shelves plate A1 and can be arranged to up and down adjustment and shelved on plate A2 under, is made
The mobile phone B 1 of different length can be adapted to by obtaining holder A, and lower positioning plate A22 plays the role of lower positioning to mobile phone B1, ensures hand
Machine B1 can be steadily seated on holder A.
In this particular embodiment, the first vertical guide chute A111 is provided in upper side shield A11, first is oriented to cunning
It can slide up and down to be provided with below the first guide post A112, the first guide post A112 in slot A111 and be connected with height regulating rod
The lower face of A3, upper side shield A11 are provided with height adjusting holes A113, and the vertical centerline of height adjusting holes A113 is led with first
It coincides to the vertical centerline of sliding slot A111, and height adjusting holes A113 is connected with the first guide chute A111, height is adjusted
It the lower part protrusion height adjustment hole A113 of pole A3 and is fixed on lower side shield A21.Pass through the first guide chute A111
With the cooperation of the first guide post A112, it play the guiding role to the movement of height regulating rod A3.
In this particular embodiment, the internal diameter of height adjusting holes A113 is more than the outer diameter of height regulating rod A3 and is less than first
The outer diameter of guide post A112.Outer diameter of the internal diameter of height adjusting holes A113 more than height regulating rod A3 is less than the first guide post A112
Outer diameter, ensure that height regulating rod A3 can be swimmingly up and down and can be stably mounted to shelve on plate A1.
In this particular embodiment, the front end face of upper side shield A11 is provided with internal thread hole A114, internal thread hole A114 with
First guide chute A111 is connected, and lock-screw F is bolted on internal thread hole A114, is adjusted height by lock-screw F
The position of bar A3 is locked.The front end face of upper side shield A11 is provided with internal thread hole A114, is bolted in internal thread hole A114
Lock-screw F is consolidated the position of height regulating rod A3 by tightening lock-screw F after the completion of the height adjusting for above shelving plate A1
It lives calmly.
In this particular embodiment, image capturing mechanism B includes the mobile phone B 1 with camera function and image capture plate B2, hand
Machine B1, which is shelved on, to be shelved in chamber E, is above shelved and is provided with the front and back image capture window A12, image capture plate B2 penetrated through on plate A1
Can slidingly it be arranged on image capture window A12, the front end face of image capture plate B2 shelves the front end face of plate A2 under
It flushes, the front and back image capture hole B21 penetrated through is provided on image capture plate B2, biochip loader mechanism C is caught positioned at image
Obtain the rear of hole B21.Above-mentioned image capturing mechanism B structure is simple, easy to operate, and front and back perforation is arranged on plate A1 in upper shelve
An image for carrying image capture hole B21 can be slidingly arranged in image capture window A12 on image capture window A12
Capture board B2 is adapted to camera by the position of left and right adjusting image capture plate B2 and the mobile phone B 1 in different location is arranged, specifically
Shelved in chamber E in use, mobile phone B 1 is set to be shelved on, the left and right position of adjustment image capture plate B2 and on shelve the upper of plate A1
Lower position enables the camera in mobile phone B 1 to be directed at image capture hole B21, and the lower part of mobile phone B 1 can stablize and be shelved on down
On positioning plate A22, the biochip loaded on biochip loader mechanism C is then captured by the mobile phone B 1 with camera function
Biological information on G.
In this particular embodiment, two inner faces up and down of image capture window A12 are provided with and image capture plate B2
Thickness matched sliding slot A121, image capture plate B2 are slidably disposed in sliding slot A121, above shelve the upper surface of plate A1
It is provided with vertical locking hole (not shown), locking hole and the sliding slot A121 on image capture window A12 upper interior ends face
It is connected, a lock-screw F is bolted on locking hole, is fixed the position of image capture plate B2 by lock-screw F.Pass through
Horizontally slipping for image capture plate B2 is realized with the matched sliding slot A121 of image capture plate B2 thickness, can be adapted to different cameras
The mobile phone B 1 of position, it is simple in structure, it is easy to operate.
In this particular embodiment, the clamp system being provided on plate A2 for mobile phone to be fixedly clamped is shelved under, is clamped
Mechanism includes width adjusting bar A23 and clamping plate A24, under shelve the front end face of plate A2 and be provided with the groove A25 being recessed backward,
Under shelve to be provided in plate A2 in the second lateral guide chute A26, the second guide chute A26 and can slidingly be provided with
It is provided with lateral resetting spring A28 between two guide post A27, the second guide post A27 and the second side end faces guide chute A26,
Width adjusting hole A251 is provided on the side end face of groove A25, the cross central line of width adjusting hole A251 and second, which are oriented to, to be slided
The cross central line of slot A26 overlaps, and width adjusting hole A251 is connected with the second guide chute A26, and the one of width adjusting bar A23
End stretches into width adjusting hole A251 and is connected with the second guide post A27, and clamping plate A24 is fixed at width adjusting bar A23's
The other end.When above-mentioned clamp system mobile phone B 1 be shelved on to shelve in chamber E, left and right position can be also accurately positioned, and be led to
It crosses the second guide chute A26 and the second guide post A27 plays guiding role, resetting spring A28 to the movement of width adjusting bar A23
Give clamping plate A24 mono- tightening force, it is simple in structure, it is easy to operate, and clamp and stablize.
In this particular embodiment, outer diameter of the internal diameter of width adjusting hole A251 more than width adjusting bar A23 and less than the
The outer diameter of two guide post A27.The internal diameter of width adjusting hole A251 is more than the outer diameter of width adjusting bar A23 and is less than the second guide post
The outer diameter of A27 so that width adjusting bar A251 can swimmingly horizontally slip and have there are one stablize positioning.
In this particular embodiment, it is pulled out with clamping plate A24 and is provided with and presss from both sides on the consistent lower side shield A21 in direction
The tight plate matched opening A212 of A24 are set with the inner side end of the clamping plate A24 lower side shield A21 that pull out direction opposite
It is equipped with neonychium A211.Setting opening A212 on the consistent lower side shield A21 in direction is being pulled out with clamping plate A24, this is opened
Mouthful A212 facilitates the operation of clamp system, and with the inner end of the clamping plate A24 lower side shield A21 that pull out direction opposite
Neonychium A211 is arranged in face, and neonychium A211 then shields to the side of mobile phone B1.
In this particular embodiment, biochip loader mechanism C includes load frame C1 and load frame mounting base C2, dress
It carries and is provided with the front and back rectangular watch window C11 penetrated through on frame C1, be vertically provided on load frame C1 and biological core
The matched first slot C12 of piece G, biochip G are inserted into the detection examination being arranged in the first slot C12 and on biochip G
Sample is located in watch window C11；The front and back cylindric inner cavity C21 penetrated through, load frame are provided on load frame mounting base C2
Be provided on mounting base C2 up and down be inserted into setting with the matched second slot C22 of load frame C1, load frame C1
In the second slot C22；Load frame mounting base C2 mounted on image capture plate B2 rear end face on, cylindric inner cavity C21 with
Image capture hole B21 is coaxial, and lens C3 is provided between image capture hole B21 and cylindrical shape inner cavity C21.Load frame C1 structures
Simply, the first slot C12 provides a stable installation positioning to biochip G, sees for making biochip G be inserted into it
Window C11 is examined convenient for observation；The second slot C22 being arranged on load frame mounting base C2 is for being inserted into load frame C1, cylinder
Shape inner cavity C21 and image capture hole B21 are coaxial, it is ensured that can be on accurate observation to biochip G by image capture hole B21
Lens C3 is arranged in biological information between image capture hole B21 and cylindrical shape inner cavity C21, by lens C3 by biochip G
On biological information amplification, can capture more clear biometric image convenient for mobile phone B 1.
In this particular embodiment, the front end face of load frame mounting base C2 is provided with the cylindrical shape for mounted lens C3
Installation cavity C23, installation cavity C23 is coaxial with cylindrical shape inner cavity C21 and the internal diameter of installation cavity C23 is more than cylindrical shape inner cavity
The internal diameter of C21, the size and the matching size of installation cavity C23 of lens C3 are closed.The installation being arranged on load frame mounting base C2
Cavity C23 is used to provide a stable installation to lens C3 and position, and installation cavity C23 and cylindrical shape inner cavity C21 is coaxial so that
Lens C3 can preferably play the effect of the biological information on amplification biochip G, and the internal diameter of installation cavity C23 is more than cylinder
The internal diameter of shape inner cavity C21, the size and the matching size of installation cavity C23 of lens C3 are closed so that lens C3 can stablize installation
In installation cavity C23, avoiding lens C3 from falling in cylindric inner cavity C21 influences normal use.
In this particular embodiment, it is provided on load frame mounting base C2 for adjusting the upper and lower positions load frame C1
Position adjusting mechanism.Upper and lower positions of the load frame C1 on load frame mounting base C2 is adjusted by position adjusting mechanism, from
And the biological information on biochip G is completely captured.
In this particular embodiment, position adjusting mechanism include mutually matched adjusting internal gear 1 and adjust external gear 2,
Load frame mounting base C2 includes the columned preceding pedestal 3 and rear pedestal 4 of coaxial arrangement, and the outer diameter of preceding pedestal 3 is more than rear base
The outer diameter of seat 4, the second slot C22 are arranged on preceding pedestal 3, and the side of load frame mounting base C2, which is uniformly distributed along the circumference, to be provided with
At least two recessed portion C24, recessed portion C24 are connected with cylindrical shape inner cavity C21, and adjusting external gear 2 is rotatably arranged in recessed
In concave portion C24, two lateral surfaces of load frame C1 are provided with and adjust 2 matched rack C13 of external gear, adjust internal gear
1 is set on rear pedestal 4 and is meshed with external gear 2 is adjusted, and load frame C1 insertions are arranged in the second slot C22 and tooth
C13 is meshed with external gear 2 is adjusted, and the rear portion of rear pedestal 4 is coaxially disposed restraining position ring block 5.Above-mentioned position adjusting mechanism, structure
Simply, easy to operate, rear pedestal 4 is used for installation and adjustment external gear 1, by preceding pedestal 3 and spacing ring 5 to adjusting internal gear 1
Installation provides front limit and rear limit, it is ensured that adjust the installation of stablizing of internal gear 1, when adjusting rotation adjust internal gear 1, band
The dynamic adjusting external gear 2 being meshed therewith rotates, and the rack C13 being meshed with the adjusting external gear 2 is driven to move up and down, from
And so that load frame C1 moves up and down along the second slot C22, realize that the upper and lower position of load frame C1 is adjusted.
In this particular embodiment, the side of rear pedestal 4 is provided with the third slot 41 of perforation, is inserted into third slot 41
It is provided with scattering sheet 6.The insertion scattering sheet 6 in third slot 41, the equalizing light rays that light source mechanism D can be emitted,
Convenient for biochip G is clearly viewed.
In this particular embodiment, the outer diameter of spacing ring 5 is more than the outer diameter of rear pedestal 4.The outer diameter of spacing ring 5 is more than rear base
The outer diameter of seat 4, it is ensured that spacing ring 5 plays stable rear position-limiting action.
In this particular embodiment, it adjusts and has been uniformly arranged anti-slop serrations 11 on the lateral wall of internal gear 1.Anti-slop serrations 11 are set
The frictional force that can increase and adjust 1 lateral wall of internal gear is set, convenient for carrying out rotation operation to it.
In this particular embodiment, light source mechanism D includes light source D1, driving power D2, light source mounting base D3 and driving electricity
Source mounting base D4, light source mounting base D3 are fixedly mounted on the rear end of spacing ring 5, and front and back perforation is provided on light source mounting base D3
And coaxial light transmission chamber D31, light source D1 are mounted in light transmission chamber D31 with cylindric inner cavity C21, the rear end of light source D1 be provided with
Power supply the conduction panel D11, driving power D2 of light source D1 electrical connections are in driving power mounting base D4, driving power mounting base
D4, which is arranged on the rear of light source mounting base D3, driving power D2, is provided with trigger board D21, the conducting of trigger board D21 face power supplys
Plate D11, when trigger board D21 is contacted with power supply conduction panel D11, power supply, which is connected, makes light source D1 shine.Above-mentioned light source mechanism D structures
Simply, given respectively by light source mounting base D3 and driving power mounting base D4 light source D1 and driving power D2 provide one it is stable
Installation space realizes closing and the opening of light source D1 by separation between power supply conduction panel D11 and trigger board D21 and contact,
It is easy to operate, it is easy to use.
In this particular embodiment, the rear end of light source mounting base D3 is provided with externally threaded mounting ring D32, and shape is not used
Under state, on mounting ring D32, trigger board D21's driving power mounting base D4 screwing sections is separated with power supply conduction panel D11, makes
Used time, screwing driving power mounting base D4 makes trigger board D21 be in contact with power supply conduction panel D11, and light source D1 shines.Above structure
Driving power mounting base D4 can not only be stably mounted on light source mounting base D3, while power supply conduction panel can be fast implemented
It separation between D11 and trigger board D21 and contacts, it is simple in structure, it is easy to operate.
In this particular embodiment, the outside portion of driving power mounting base D4 has been uniformly arranged anti-slop serrations D41.Anti-slop serrations
The setting of D41 can increase the frictional force of driving power mounting base D4 lateral walls, convenient for carrying out rotation operation to it.
In this particular embodiment, lower side shield A21, which extends back, is provided with adjutage A29.Adjutage A29 is to entirely propping up
Frame A plays a supporting role.
When specifically used above-mentioned bio-chip test device, mobile phone B 1 is shelved on the shelving in chamber E of holder A, in adjusting
The position for shelving plate A1 and image capture plate B2 makes the camera in mobile phone B 1 be directed at image capture hole B21, will carry detection examination
The biochip G of sample is inserted into load frame C1, and detection sample is made to be located in watch window C11, and load frame C1 is inserted
Enter into the second slot C22 on load frame mounting base C2, rotate driving power mounting base D4, make power supply conduction panel D11 with
Trigger board D21 is in contact, and circuit of light sources conducting, light source D1 shines, and opens the camera function of mobile phone B 1, at this time just it can be seen that logical
The biological information for crossing the detection sample on the biochip G of lens C3 amplifications, load frame C1 is adjusted by position adjusting mechanism
Upper and lower position, such mobile phone B 1 just can capture on different location detection sample biological information, by mobile phone B 1 to not
Biological information with the detection sample on position is taken pictures, and clear biometric image information just can be obtained.
In this particular embodiment, enriching apparatus further include enrichment test tube K, enrichment box H include bottom plate H11, top plate H12,
Backboard H13 and two side plate H14, bottom plate H11 are horizontally disposed, and two side plate H14 are vertically provided at the both sides of bottom plate H11 respectively,
Backboard H13 is vertically provided on bottom plate H11 and the both sides of backboard H13 are connected with two side plate H14 respectively, and the two of top plate H12
Side can be arranged to pull on the inner side end of two side plate H14 respectively, bottom plate H11, top plate H12, backboard H13 and two sides
The cavity for being set as a front opening is enclosed between plate H14, one is horizontally arranged in cavity and shelves plate H3, shelves the both sides point of plate H3
It is not connected with two side plate H14, shelves and be connected by a vertically arranged support plate H4 between plate H3 and bottom plate H11, put
Set be provided on plate H3 it is multiple with enrichment test tube K is matched shelves through-hole H31, enrichment test tube K, which is shelved on, shelves through-hole H31
It is interior, it is provided with immunomagnetic beads K21 in enrichment test tube K, magnet (not shown) is provided on support plate H4.The enriching apparatus knot
Structure is simple, easy to operate, constitutes an enrichment frame by shelving plate H3, support plate H4 and bottom plate H11, magnetic is arranged in support plate H4
Iron is enriched on frame and shelves the enrichment test tube K with immunomagnetic beads K21, and when use pours into Biosample equipped with immunomagnetic beads K21
Enrichment test tube K in, adsorbed by immunomagnetic beads K21 with the biology that immunomagnetic beads K21 matches, then Biosample will be housed
Enrichment test tube K be shelved on enrichment frame, the immunomagnetic beads K21 that detection biology will be adsorbed with by the magnet on support plate H4 inhales
It is attached on test tube wall, then the entire enrichment box H of operation pours out remaining Biosample, just can effectively be enriched to and need to detect
Biological sample；The sky for being set as a front opening is enclosed additionally by bottom plate H11, top plate H12, backboard H13 and two side plate H14
Chamber, the setting of the opening are convenient for observing the enrichment condition of biological sample；The both sides top plate H12 can be arranged to pull respectively
On the inner side end of two side plate H14, the position of top plate is adjusted by draw operation, picking and placeing and operating convenient for enrichment test tube K.
In this particular embodiment, support plate H4 be arranged the centre position of cavity by bottom plate H11 be divided into noseplate and
The both sides of bottom plate afterwards, support plate H4 are connected with two side plate H14 respectively, shelve the top that plate H3 is located at noseplate, rear bottom plate,
It is enclosed between support plate H4, backboard H13 and two side plate H14 and is set as object placing cavity H5, noseplate shelves plate H3, support plate H4 and two
It is enclosed between a side plate H14 and is set as an enrichment chamber.Support plate H4 is arranged in the centre position of cavity so that cavity, which is divided into, to be set
Object chamber H5 and enrichment chamber two chambers, object placing cavity H5 can be used for putting to be adopted with the relevant article of biological specimen collection, such as glass slide
Sample reagent etc. so that the enriching apparatus is provided simultaneously with function of containing articles, vdiverse in function.
In this particular embodiment, enrichment intracavitary is vertically uniformly arranged at intervals with multiple partition board H7, adjacent two partition boards
An independent enrichment room H61 is formed between H7, is each enriched on the H61 of room there are one being correspondingly arranged and is shelved through-hole H31.Pass through
Entire enrichment chamber is separated into multiple independent enrichment room H61 by partition board H7, and each room H61 that is enriched with can carry out independent enrichment behaviour
Make, convenient for observation and distinguishes.
In this particular embodiment, it is each provided with one in enrichment room H61 and shelves a H8, shelve before a H8 is fixed at
It on bottom plate, shelves to be provided on a H8 and shelves cavity H81, shelve cavity H81 and be located at the underface for shelving through-hole H31.Shelve seat
So that shelving for enrichment test tube K is more stablized, the bottom of enrichment test tube K, which is shelved on, shelves in cavity H81, avoids working as the setting of H8
Be enriched with box H by when outer force effect be enriched with test tube K double swerves, to influence concentration effect, and shelve cavity H81 be located at put
The underface of through-hole H31 is set, ensures shelving vertically to shelve for enrichment test tube K, ensures concentration effect.
In this particular embodiment, magnet insertion is arranged in support plate H4.Magnet insertion is arranged in support plate H4
Portion avoids magnet from being chronically exposed in air and chemical reaction influence adsorption effect occurs.
In this particular embodiment, the upper interior end face of two side plate H14 is provided with and the matched cunning of top plate H12 thickness
The both sides of slot H141, top plate H12 are slidably disposed in sliding slot H141.The front and back pumping of top plate H12 is realized by sliding slot H141
It draws, is convenient for being enriched with and picking and placeing the operation of article, it is simple in structure, it is easy to operate.
In this particular embodiment, it shelves and is provided with vertical baffle H32 on plate H3.Baffle H32 is for preventing glove
Object in chamber H5 drops out.
In this particular embodiment, the tread plate H121 to raise up is provided on top plate H12.Tread plate H121 is convenient for use
Hand operates the pull of top plate H12.
In this particular embodiment, the arrow H122 for being used to indicate pull direction is provided on top plate H12.Indicator
Head H122 is used to indicate the pull direction of top plate H12, avoids maloperation.
When the above-mentioned enrichment test tube of concrete operations, be put into being enriched with test tube K match with biological sample to be extracted it is immune
Then magnetic bead K21 pours into Biosample in enrichment test tube K, the biology to match with immunomagnetic beads K21 is by immunomagnetic beads
K21 is adsorbed, and then the enrichment test tube K equipped with Biosample is shelved on enrichment frame, will be inhaled by the magnet on support plate H4
It is adsorbed onto on test tube wall with the immunomagnetic beads K21 of detection biology, then enrichment box H is tilted, liquid in enrichment test tube K is made to fall
Go out, just can effectively be enriched to the biological sample for needing to detect.
In this particular embodiment, vertical installation sliding slot H142 is provided on two side plate H14, under shelve plate A2 after
End face is oppositely arranged there are two support arm A20, is provided on the inner face of two support arm A20 and is installed sliding slot H142 and match
Installation sliding block A201, installation sliding slot H142 realizes the disassembly and installation of enrichment box H with the cooperation for installing sliding block A201.
Above-mentioned biological chips detection system using mobile phone obtain biometric image, therefore whole device can manufacture ground volume compared with
It is small, it is suitable for using in palm, it is easy to operate.
Embodiment two：Other parts are identical as embodiment one, the difference is that being provided on adjutage A29 for branch
Support the support leg 9 of holder A.It is provided with support leg 9 on adjutage A29 and further functions as supporting role to entire holder A, makes
It obtains entire holder A and is stabilized support.
In this particular embodiment, 9 support angle of support leg is adjustable and can move up and down along adjutage A29.9 jiaos of support leg
It spends adjustable and can move up and down along adjutage A29 so that the support angle of holder A is adjustable, convenient for the hand being shelved on holder A
Machine B1 is operated.
Claims (6)
1. a kind of biological chips detection system, including bio-chip test device and the enriching apparatus for biological specimen collection,
It is characterized in that the bio-chip test device includes holder, image capturing mechanism, biology are provided on the holder
Chip loader mechanism and light source mechanism, the image capturing mechanism are arranged before the biochip loader mechanism, institute
The light source mechanism stated is arranged after the biochip loader mechanism；The enriching apparatus includes enrichment box, described
Enrichment box is removably disposed on the holder, and object placing cavity is provided in the enrichment box, is received in the object placing cavity
It receives and is provided with hybridizing reagent, hybridizing box and biochip；
The holder include shelved on vertically arranged plate and under shelve plate, it is described on shelve plate and can be arranged to up and down adjustment
Shelve the top of plate under described, it is described on shelve the front end face of plate with it is described under shelve the front end face of plate and flush, institute
The both sides that plate is shelved on stating are respectively arranged with the upper side shield extended forward, and the both sides that plate is shelved under described are respectively forwardly prolonged
Stretch and be provided with lower side shield, the upper side shield and the downside baffle position up and down with respect to and the upper side shield
Inner side end is flushed with the inner side end of the lower side shield, and the lower part of plate is shelved under described and is extended forward transverse direction
Lower positioning plate, the upper side shield, lower side shield, on shelve plate, under shelve to enclose between plate and the lower positioning plate and set
Chamber is shelved at one；
The image capturing mechanism includes the mobile phone with camera function and image capture plate, and the mobile phone is shelved on described
Shelve intracavitary, it is described on shelve and be provided with the front and back image capture window penetrated through on plate, the image capture plate can control
Be slidably arranged on the image capture window, the front end face of the image capture plate with it is described under shelve plate before
End face is provided with the front and back image capture hole penetrated through, the biochip loader mechanism on the image capture plate
Rear positioned at the image capture hole；
The biochip loader mechanism includes load frame and load frame mounting base, is provided in the load frame
The rectangular watch window of front and back perforation is vertically provided in the load frame and is inserted with biochip matched first
Slot, biochip insertion is arranged in first slot and the detection sample on the biochip is located at institute
In the watch window stated；The front and back cylindric inner cavity penetrated through, the loading frame are provided in the load frame mounting base
Be provided in frame mounting base up and down with matched second slot of load frame, the load frame be inserted into
It is arranged in second slot；The load frame mounting base is mounted on the rear end face of the image capture plate,
The cylindric inner cavity and the image capture hole are coaxial, between the image capture hole and the cylindric inner cavity
It is provided with lens；
The position adjusting mechanism for adjusting load frame upper and lower position is provided in the load frame mounting base, it is described
Position adjusting mechanism includes mutually matched adjusting internal gear and adjusts external gear, and the load frame mounting base includes coaxial
The columned preceding pedestal being arranged and rear pedestal, the outer diameter of the preceding pedestal is more than the outer diameter of the rear pedestal, described
Second slot is arranged on the preceding pedestal, and the side of the load frame mounting base is symmetrical arranged there are two recessed portion,
The recessed portion is connected with the cylindric inner cavity, and the adjusting external gear is rotatably arranged in the recess
In portion, two lateral surfaces of the load frame are provided with and the matched rack of adjusting external gear, the tune
Section inner gear housing is located on the rear pedestal and is meshed with the adjusting external gear, and the load frame is inserted into setting
In second slot and the rack is meshed with the adjusting external gear, and the rear portion of the rear pedestal is coaxial
Restraining position ring block is set.
2. a kind of biological chips detection system as described in claim 1, it is characterised in that the light source mechanism include light source,
Driving power, light source mounting base and driving power mounting base, the light source mounting base are fixedly mounted on the spacing ring
Rear end, be provided in the light source mounting base it is front and back penetrating through and with the light transmission chamber of the cylindric coaxial, it is described
Light source be mounted on the light transmission intracavitary, the rear end of the light source is provided with to be connected with the power supply of light source electrical connection
Plate, the driving power are mounted in the driving power mounting base, and the driving power mounting base is arranged described
Light source mounting base rear, be provided with trigger board in the driving power, the power supply described in the trigger board face is led
Logical plate, when the trigger board is contacted with the power supply conduction panel, power supply, which is connected, makes the light source luminescent.
3. a kind of biological chips detection system as described in claim 1, it is characterised in that the enriching apparatus further includes richness
Collect test tube, the enrichment box includes bottom plate, top plate, backboard and two side plates, floor level setting, described in two
Side plate is vertically provided at the both sides of the bottom plate respectively, and the backboard is vertically provided on the bottom plate and the back of the body
The both sides of plate are connected with the side plate described in two respectively, and the both sides of the top plate can be arranged to pull respectively described in two
Side plate inner side end on, enclose the sky for being set as a front opening between the bottom plate, top plate, backboard and two side plates
Chamber is horizontally arranged with one in the cavity and shelves plate, and the both sides for shelving plate are connected with the side plate described in two respectively
It connects, described shelving is connected between plate and the bottom plate by a vertically arranged support plate, and described shelving is set on plate
Be equipped with it is multiple it is matched with the described enrichment test tube shelve through-hole, the enrichment test tube be shelved on described in shelve through-hole
It is interior, it is provided with immunomagnetic beads in the enrichment test tube, magnet is provided in the support plate.
4. a kind of biological chips detection system as claimed in claim 3, it is characterised in that the support plate is arranged described
The centre position of cavity the bottom plate is divided into noseplate and rear bottom plate, the both sides of the support plate respectively with two
The side plate is connected, the top shelved plate and be located at the noseplate, the rear bottom plate, support plate, backboard
It is enclosed between two side plates and is set as the object placing cavity, the noseplate is shelved to enclose between plate, support plate and two side plates and set
At an enrichment chamber.
5. a kind of biological chips detection system as claimed in claim 4, it is characterised in that the enrichment intracavitary is vertically uniformly distributed
Multiple partition boards are arranged at intervals with, form an independent enrichment room, each richness between the partition board described in adjacent two
It is correspondingly arranged on collection room and shelves through-hole there are one described, each enrichment interior is provided with one and shelves seat, and described puts
It sets seat to be fixed on the noseplate, described shelving is provided on seat shelves cavity, and the cavity of shelving is located at
The underface for shelving through-hole.
6. a kind of biological chips detection system as claimed in claim 3, it is characterised in that be provided on the side plate described in two
Vertical installation sliding slot, the rear end face that plate is shelved under described are oppositely arranged there are two support arm, the support arm described in two
It is provided on inner face and the matched installation sliding block of the installation sliding slot, the installation sliding slot and the cooperation for installing sliding block
Realize the disassembly and installation of the enrichment box.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611234353.3A CN106680471B (en) | 2016-12-28 | 2016-12-28 | A kind of biological chips detection system |
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| DE102017120495A1 (en) * | 2017-09-06 | 2019-03-07 | Gottfried Wilhelm Leibniz Universität Hannover | Holding structure, optical sensor module and set formed from it |
| CN109613289A (en) * | 2018-12-27 | 2019-04-12 | 宁波大学 | A kind of qualitative/quantitative biological chips detection system |
| CN111190021B (en) * | 2020-02-22 | 2023-08-11 | 武汉泰沃科技有限责任公司 | Biological sample processing box |
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