CN106706590A - Portable fluorescence chip data collector - Google Patents
Portable fluorescence chip data collector Download PDFInfo
- Publication number
- CN106706590A CN106706590A CN201710083505.2A CN201710083505A CN106706590A CN 106706590 A CN106706590 A CN 106706590A CN 201710083505 A CN201710083505 A CN 201710083505A CN 106706590 A CN106706590 A CN 106706590A
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- China
- Prior art keywords
- light source
- fluorescence
- pull
- chip data
- portable fluorescence
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6402—Atomic fluorescence; Laser induced fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The invention relates to a portable fluorescence chip data collector. The portable fluorescence chip data collector comprises a main case body and a drawing case, wherein the drawing case is movably installed in the main case body through a guide rail and can be drawn out from one side of the main case body; the top of the main case body is provided with a fluorescence light source; the top of the drawing case is provided with a first light filter; the bottom of the drawing case is provided with a chip bracket; the chip bracket is tilted to the drawing direction of the drawing case against the bottom surface of the drawing case; and a viewing port is arranged at one side in the drawing direction of the drawing case. The portable fluorescence chip data collector is convenient to carry, has no region or time limit, and is a digital portable fluorescence interpretation apparatus, thereby providing a sensitive quick specific cheap high-efficiency data collector for special anti-counterfeiting actions against illegal addition of nonsteroidal anti-inflammatory drugs and analogs thereof, and making a contribution to ensuring quality safety of food and drugs for the masses.
Description
Technical field
The present invention relates to field of food detection, more particularly to a kind of Portable fluorescence chip data Acquisition Instrument.
Background technology
Target substance is identified using large biological molecule, is the hot technology of Safety of Food Quality detection, based on anti-
The immunology detection technology of original/antibody response is main flow therein, have the advantages that it is sensitive, special, quick and cheap, extensively
It is applied to the quick detection of Food and environment sample.And be capable of identify that many residual immune detections of a class material, one detected
The high flux detection of the various orthogonal materials of journey Parallel testing, is the cutting edge technology neck of the complicated food safety detection task of reply
Domain.
Illicit drugs phenomenon remains incessant after repeated prohibition in current food, and has the today for the trend of growing in intensity, national drug prison
Pipe portion door is annual all to arrange substantial amounts of manpower and materials, carries out special detection action of cracking down on counterfeit goods.But due to HPLC, LC-MS so
Instrument and equipment, the only drug inspection department of provinces and cities' one-level uses, and operating cost is high, it is difficult to extensive to carry out, and leads
The batch and scope of the special detection of illegal additive is caused all to be limited to.And high-end devices as LC-ESI-MS, it is many provincial
Medicine inspecting institute may not all be equipped with, therefore the non-steroidal anti-inflammatory analogue for continuously emerging, it appears helpless.
Instrument and equipment as similar HPLC, LC-MS is desk-top instrument, and desk-top fluorescence detector is typically placed in detection
Interior, has some limitations in use, moves and carries very inconvenient, it is impossible to accomplishes according to demand whenever and wherever possible
Site Detection.Need for detection sample to take back sensing chamber during use, then carry out Data Detection and data analysis.Therefore design
A kind of Portable fluorescence chip data Acquisition Instrument is necessary.
The content of the invention
In order to solve the above-mentioned technical problem, it is convenient for carrying the invention provides a kind of, the Fluorescence chip number of convenient use
According to Acquisition Instrument.
The technical solution adopted in the present invention is:A kind of Portable fluorescence chip data Acquisition Instrument, including main box and take out
Draw case.The pull-out box is movably arranged in main box by guide rail, it is possible to pull out to come from main box side.The main tank
Body top is provided with fluorescence light source, and the first optical filter is installed at the pull-out box top, and the pull-out box bottom is provided with chip branch
Frame, the chip set favours pull-out box bottom surface towards pull-out box extraction direction, and the pull-out box extraction direction side is set
There is observation port.
Further, the fluorescence light source is divided into the first light source and secondary light source, and first light source connects first switch, institute
State secondary light source connection second switch.When a fluorescence light source is faulty, it is possible to use another fluorescence light source.
Further, the observation port is provided with the second optical filter.Filtering veiling glare, makes fluorescence data more accurate.
Further, it is provided with shooting fixed support by the observation port.Shooting fixed support can fix mobile phone, camera etc.
Portable capture apparatus shoot to Fluorescence chip data.
Further, the fluorescence light source is ultraviolet light source.
Further, first optical filter is the optical filter for only allowing the light wave by 365nm wavelength.
Further, second optical filter is the optical filter for only allowing the light wave by 610~630nm wavelength.
The present invention is provided with chargeable storage, can support to detect work on the spot 6-8 hours in remote districts.Observation port
Shooting fixed support can connect the electronic equipment with shoot function such as panel computer, mobile phone, by camera to chip clap
According to mode directly the digital code information of testing result is acquired, result is divided by embedded in mobile phone picture analyzing software
Analysis is processed.Can directly store and utilize network remote to send to treated data, realize the teleengineering support of information.It is pin
To the special anti fake commodity campaign of illegal addition non-steroidal anti-inflammatory and the like, there is provided sensitive, quick, special, inexpensive, efficient number
According to Acquisition Instrument, for the work for ensureing people's food and medicine quality safety contributes.
Brief description of the drawings
Fig. 1 is the structural representation of Portable fluorescence chip data Acquisition Instrument of the invention.
Fig. 2 is the front view of Portable fluorescence chip data Acquisition Instrument of the invention.
Fig. 3 is the top view of Portable fluorescence chip data Acquisition Instrument of the invention.
Specific embodiment
As shown in Figures 1 to 3, a kind of Portable fluorescence chip data Acquisition Instrument of the invention, including main box 1 and pull-out box 2.
The pull-out box 2 is movably arranged in main box 1 by guide rail 3, it is possible to pull out to come from the side of main box 1.Will when using
Pull-out box 2 is somewhat extracted out, pushes in main box 1 pull-out box 2 when not using.
The top of the main box 1 is provided with fluorescence light source 4.Specifically, 4 points of the fluorescence light source is the first light source 41 and the
Two light sources 42, first light source 41 connects first switch 51, the connection second switch 52 of the secondary light source 42.When a fluorescence
When light source 4 is faulty, it is possible to use another fluorescence light source 4.Specifically, shown fluorescence light source 4 is ultraviolet light source, is opened
Ultraviolet can be launched after light source.
The first optical filter 6 is installed at the top of the pull-out box 2, and specifically, first optical filter 6 is only to allow to pass through
The optical filter of the light wave of 365nm wavelength.The ultraviolet light that fluorescence light source 4 sends by after the first optical filter 6, only wavelength 365nm
Light can pass through, be radiated in detection chip, the light wave of the wavelength can just make detection chip send fluorescence.
The bottom of the pull-out box 2 is provided with chip set 7, and the chip set 7 is favoured towards the extraction direction of pull-out box 2
The bottom surface of pull-out box 2.Chip set 7 is used to place detection chip.
The extraction direction side of the pull-out box 2 is provided with observation port 8, and further, the observation port 8 is provided with the second optical filtering
Piece 9.Filtering veiling glare, makes the fluorescence data of chip more accurate.Specifically, second optical filter 9 only to allow by 610~
The optical filter of the light wave of 630nm wavelength.After chip sends fluorescence, filtered by the second optical filter 9, can only be received in observation port 8
To the light that wavelength is 610~630nm.
Further, shooting fixed support 10 is provided with by the observation port 8.Shoot fixed support 10 can fix mobile phone,
The portable capture apparatus such as camera or panel computer shoot to Fluorescence chip data.
Specific explanations concrete operation method of the invention below:Sample solution and grand array films antibody chip will be detected first
With reference to, then grand array films antibody chip is placed on chip set 7, chip is subject to irradiating for fluorescence light source 4.
In detection process, the antibody in target inspection product array element corresponding to grand array films antibody chip in sample solution is combined, and is concentrated to
Detection zone (is assembled) in array element, and the ultraviolet after fluorescence light source 4 is filtered by the first optical filter 6 excites lower generation significantly
Fluorescence signal, the fluorescence signal that chip sends is can see through observation port 8.
Mobile phone or other capture apparatus are fixed on shooting fixed support 10, camera against observation panel, using taking the photograph
As head shoots to the fluorescence signal of chip.Fluorescence chip photo after shooting can be carried out by embedded in mobile phone analysis software
Analysis, or laboratory is sent to by network, it is analyzed using special instrument.
The present invention is convenient for carrying, and is to be adapted to the biometrics portable fluorescence that work detects in basic unit not by region and time restriction
Interpretation equipment, is the special anti fake commodity campaign for illegal addition non-steroidal anti-inflammatory and the like, there is provided sensitive, quick, special,
Inexpensive, efficient data collecting instrument, for the work for ensureing people's food and medicine quality safety contributes.
Embodiment described above only expresses several embodiments of the invention, and its description is more specific and detailed, but simultaneously
Can not therefore be construed as limiting the scope of the patent.It should be pointed out that coming for one of ordinary skill in the art
Say, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Scope.
Claims (7)
1. a kind of Portable fluorescence chip data Acquisition Instrument, it is characterised in that:Including main box and pull-out box, the pull-out box leads to
Cross guide rail to be movably arranged in main box, it is possible to pull out to come from main box side;The main box top is provided with fluorescence
The first optical filter is installed at light source, the pull-out box top, and the pull-out box bottom is provided with chip set, the chip set court
Pull-out box extraction direction and favour pull-out box bottom surface, the pull-out box extraction direction side is provided with observation port.
2. Portable fluorescence chip data Acquisition Instrument according to claim 1, it is characterised in that:The fluorescence light source is divided into
First light source and secondary light source, first light source connect first switch, and the secondary light source connects second switch.
3. Portable fluorescence chip data Acquisition Instrument according to claim 1, it is characterised in that:The observation port is provided with
Second optical filter.
4. Portable fluorescence chip data Acquisition Instrument according to claim 1, it is characterised in that:The observation port side is set
There is shooting fixed support.
5. Portable fluorescence chip data Acquisition Instrument according to claim 1, it is characterised in that:The fluorescence light source is purple
Outer line source.
6. Portable fluorescence chip data Acquisition Instrument according to claim 1, it is characterised in that:First optical filter is
Only allow the optical filter of the light wave by 365nm wavelength.
7. Portable fluorescence chip data Acquisition Instrument according to claim 3, it is characterised in that:Second optical filter is
Only allow the optical filter of the light wave by 610~630nm wavelength.
Priority Applications (1)
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CN201710083505.2A CN106706590A (en) | 2017-02-16 | 2017-02-16 | Portable fluorescence chip data collector |
Applications Claiming Priority (1)
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CN201710083505.2A CN106706590A (en) | 2017-02-16 | 2017-02-16 | Portable fluorescence chip data collector |
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CN106706590A true CN106706590A (en) | 2017-05-24 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113533269A (en) * | 2021-06-08 | 2021-10-22 | 东南大学 | Portable urine glucose meter and detection method thereof |
Citations (5)
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CN101281120A (en) * | 2008-05-29 | 2008-10-08 | 夏云厚 | Rock debris fluorescent / general light digitization imaging acquiring instrument and analyze management system |
CN104237210A (en) * | 2013-06-08 | 2014-12-24 | 北京百康芯生物科技有限公司 | Portable detection device |
CN105388131A (en) * | 2014-09-09 | 2016-03-09 | 国家纳米科学中心 | Fluorescence detection instrument and system based on micro-fluidic chip |
CN105842217A (en) * | 2016-05-19 | 2016-08-10 | 西安交通大学 | Up-conversion fluorescence tomography test paper detection result reading device based on mobile terminal |
CN106404733A (en) * | 2016-09-18 | 2017-02-15 | 天津博硕东创科技发展有限公司 | Mobile intelligent terminal-based food safety detection device and method |
-
2017
- 2017-02-16 CN CN201710083505.2A patent/CN106706590A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101281120A (en) * | 2008-05-29 | 2008-10-08 | 夏云厚 | Rock debris fluorescent / general light digitization imaging acquiring instrument and analyze management system |
CN104237210A (en) * | 2013-06-08 | 2014-12-24 | 北京百康芯生物科技有限公司 | Portable detection device |
CN105388131A (en) * | 2014-09-09 | 2016-03-09 | 国家纳米科学中心 | Fluorescence detection instrument and system based on micro-fluidic chip |
CN105842217A (en) * | 2016-05-19 | 2016-08-10 | 西安交通大学 | Up-conversion fluorescence tomography test paper detection result reading device based on mobile terminal |
CN106404733A (en) * | 2016-09-18 | 2017-02-15 | 天津博硕东创科技发展有限公司 | Mobile intelligent terminal-based food safety detection device and method |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113533269A (en) * | 2021-06-08 | 2021-10-22 | 东南大学 | Portable urine glucose meter and detection method thereof |
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