CN106668514A - 一种治疗少精症的药物及其制备方法 - Google Patents
一种治疗少精症的药物及其制备方法 Download PDFInfo
- Publication number
- CN106668514A CN106668514A CN201710185036.5A CN201710185036A CN106668514A CN 106668514 A CN106668514 A CN 106668514A CN 201710185036 A CN201710185036 A CN 201710185036A CN 106668514 A CN106668514 A CN 106668514A
- Authority
- CN
- China
- Prior art keywords
- gram
- grams
- fructus
- impurity
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/487—Psoralea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗少精症的药物及其制备方法,其主要是由肉苁蓉、淫羊藿、枸杞子、鹿角胶、覆盆子、菟丝子、山药、续断、巴戟天、沙苑子、黄精、紫河车、杜仲、太子参、远志、五味子、蛇床子、金樱子、仙茅、补骨脂、升麻、柏子仁、山茱萸按一定重量配比制备而成,本发明药物具有补肝肾,助阳固精,养心安神,补气养血,祛风湿的功能,用于治疗少精症见效快、疗效好,不复发。
Description
技术领域
本发明涉及一种治疗少精症的药物及其制备方法,属中药领域。
背景技术
少精症是指具有生育能力男性精液中的精子数目低于正常的一种病症。中医则认为少精症与肾精亏损,命门火衰,气血两虚,湿热下注有关。由于西药治疗副作用大,因此人们对有效治疗少精症的中药药物存在极大的需求,至今为止,还没有发现关于本发明的有关报道。
发明内容
本发明人依据中医理论的研究和临床试验的反复验证,终于找到了有效治疗少精症的药物,从而完成了本发明。
本发明的目的就是提供一种有效治疗少精症的中药组合药物。
本发明的另一目的就是提供了该中药组合药物的制备方法。
本发明药物是选择肉苁蓉、淫羊藿、枸杞子、鹿角胶、覆盆子、菟丝子、山药、续断、巴戟天、沙苑子、黄精、紫河车、杜仲、太子参、远志、五味子、蛇床子、金樱子、仙茅、补骨脂、升麻、柏子仁、山茱萸、知母、王不留行、牛膝进行组合制备的,将这些药物组合使得各药物功效产生协同作用,从而能够有效治疗少精症。其中选用肉苁蓉是因为其性味甘酸咸,温,入肾、大肠经,有补肾,益精,润燥,清肠的功能,治男子阳痿,女子不孕,带下,血崩,腰膝冷痛,血枯便秘。选用淫羊藿是因为其性味辛甘,温,入肝、肾经,有补肾壮阳,祛风除湿的功能,治阳痿不举,小便淋沥,筋骨挛急,半身不遂,腰膝无力,风湿痹痛,四脚不仁。选用枸杞子是因为其性味甘,平,有滋肾,润肺,补肝,明目的功能,治肝肾阴亏,腰膝酸软,头晕目眩,目昏多泪,虚劳咳嗽,消渴,遗精。选用鹿角胶是因为其性味甘咸,温,入肝、肾经,有补血,益精的功能,治肾气不足,虚劳羸瘦,腰痛,阴疽,男子阳痿、滑精,妇女子宫虚冷,崩漏,带下。选用覆盆子是因为其性味甘,酸,平,入肝、肾二经,有补肝肾,缩小便,助阳,固精,明目的功能,治阳痿,遗精,溲数,遗溺,虚劳,目暗。选用菟丝子是因为其性味辛甘,平,入肝、肾经,有补肝肾,益精髓,明目的功能,治腰膝酸痛,遗精,消渴,尿有余沥,目暗。选用山药是因为其性味苦甘,平,入肺、脾、肾经,有健脾,补肺,固肾,益精的功能,治脾虚泄泻,久痢,虚劳咳嗽,消渴,遗精、带下,小便频数。选用续断是因为其性味苦辛,微温,入肝、肾经,有补肝肾,续筋骨,调血脉的功能,治腰背酸痛,足膝无力,胎漏,崩漏,带下,遗精,跌打损伤,金疮,痔漏,痈疽疮肿。选用巴戟天是因为其性味辛甘,温,入肝、肾经,有补肾阳,壮筋骨,祛风湿的功能,治阳痿,少腹冷痛,小便不禁,子宫虚冷,风寒湿痹,腰膝酸痛。选用沙苑子是因为其性味甘温,入肝、肾经,有补肝,益肾,明目,固精的功能,治肝肾不足,腰膝酸痛,目昏,遗精早泄,小便频数,遗尿,尿血,白带。选用黄精是因为其性味甘平,入脾、肺、肾经,有补中益气,润心肺,强筋骨的功能,治虚损寒热,肺痨咳血,病后体虚食少,筋骨软弱,风湿疼痛,风癞癣疾。选用紫河车是因为其性味甘咸,温,入肺、肝、肾经,有补气,养血,益精的功能,治虚损,羸瘦,劳热骨蒸,咳喘,咯血,盗汗,遗精,阳痿,妇女血气不足,不孕或乳少。选用杜仲是因为其性味甘微辛,温,入肝、肾经,有补肝肾,强筋骨,安胎的功能,治腰脊酸疼,足膝痿弱,小便余沥,阴下湿痒,胎漏欲堕,高血压。选用太子参是因为其性味甘苦,微温,入心、脾、肺三经,有补肺、健脾的功能,治肺虚咳嗽,脾虚食少,心悸目汗,精神疲乏。选用远志是因为其性味苦辛,温,入心、肾经,有安神益智,祛痰,解郁的功能,治惊悸,健忘,梦遗,失眠,咳嗽多痰,痈疽疮肿。选用五味子是因为其性味酸,温,入肺、肾经,有敛肺,滋肾,生津,收汗,涩精的功能,治肺虚喘咳,口干作渴,自汗,盗汗,劳伤羸瘦,梦遗滑精,久泻久痢。选用蛇床子是因为其性味辛苦,温,入肾、脾经,有温肾助阳,祛风,燥湿,杀虫的功能,治男子阳痿,阴囊湿痒,女子带下阴痒,子宫寒冷不孕,风湿痹痛,疥癣湿疮。选用金樱子是因为其性味酸涩,平,有固精涩肠,缩尿止泻的功能,治滑精,遗尿,小便频数,脾虚泻痢。选用仙茅是因为其性味辛,温,有毒,入肾、肝经,有温肾阳,壮筋骨的功能,治阳萎精冷,小便失禁,崩漏,心腹冷痛,腰脚冷痹,痈疽,瘰疬。补骨脂是因为其性味辛,温。入肾经。补肾助阳。治肾虚冷泻,遗尿,滑精,小便频数,阳瘘,腰膝冷痛,虚寒喘嗽。选用升麻是因为其性味甘辛微苦,凉,入肺、脾、胃经,有升阳,发表,透疹,解毒的功能,治时气疫劳,头痛寒热,喉痛,口疮疤,斑疹不透,中气下陷,久泻久痢,脱肛,妇女崩带,子宫下坠,痈肿疮毒。选用柏子仁是因为其性味甘,平,入心、肝、脾经,有养心安神,润肠通便的功能,治惊悸,失眠,遗精,盗汗,便秘的功能。选用山茱萸是因为其性味酸,微温,入肝、肾经,有补肝肾,涩精气,固虚脱的功能,治腰膝酸痛,眩晕,耳鸣,阳痿,遗精,小便频数,肝虚寒热,虚汗不止,心摇脉散。选用知母是因为其性味苦,寒,入肺、胃、肾经,有滋阴降火,润燥滑肠的功能,治烦热消渴,骨蒸劳热,肺热咳嗽,大便燥结,小便不利。选用王不留行是因为其性味苦平,入肝、胃经,有行血通经,催生下乳,消肿敛疮的功能,治妇女经闭,乳汁不通,难产,血淋,痈肿,金疮出血。选用牛膝是因为其性味甘苦酸,平,入肝、肾经,生用散瘀血,消痈肿的功能,治淋病,尿血,经闭,癥瘕,难产,胞衣不下,产后瘀血腹痛,喉痹,痈肿,跌打损伤,熟用补肝肾,强筋骨,治腰膝骨痛,四肢拘挛,痿痹。
具体实施方式
本发明组分的药物用量也是发明人经过大量摸索总结得出的,各组分的用量在下述重量范围内都具有较好的疗效:
肉苁蓉10-20克,淫羊藿10-20克,枸杞子10-15克,鹿角胶10-20克,覆盆子10-15克,菟丝子10-15克,山药15-20克,续断10-15克,巴戟天10-20克,沙苑子10-15克,黄精10-20克,紫河车5-15克,杜仲5-15克,太子参10-20克,远志10-15克,五味子5-15克,蛇床子5-15克,金樱子10-15克,仙茅5-10克,补骨脂10-15克,升麻5-15克,柏子仁5-15克,山茱萸5-10克,知母10-15克,王不留行10-20克,牛膝5-15克。
优选为:
肉苁蓉15克,淫羊藿15克,枸杞子12克,鹿角胶15克,覆盆子12克,菟丝子12克,山药18克,续断12克,巴戟天15克,沙苑子12克,黄精15克,紫河车10克,杜仲10克,太子参15克,远志12克,五味子10克,蛇床子10克,金樱子12克,仙茅8克,补骨脂12克,升麻10克,柏子仁10克,山茱萸8克,知母12克,王不留行15克,牛膝10克。
本发明药物的制备方法如下
一、备料
1、肉苁蓉:拣净杂质,清水浸泡,每天换水1-2次,如系咸苁蓉,泡尽盐分,润透,纵向切片,晒干;
2、淫羊藿:拣净杂质,去梗,切丝,筛去碎屑;
3、枸杞子:簸净杂质,摘去残留的梗和蒂;
4、鹿角胶:取原药材,除去杂质,用时捣碎;
5、覆盆子:筛去灰屑,拣净杂质,去柄;
6、菟丝子:过箩去净杂质,洗净,晒干;
7、山药:拣净杂质,用水浸泡至山药中心部软化为止,捞出稍晾,切片晒干或烘干;
8、续断:洗净泥沙,除去残留根头,润透后切片晒干,筛去屑;
9、巴戟天:拣去杂质,用热水泡透后,趁热抽去水心,切段,晒干;
10、沙苑子:拣去杂质,漂净泥沙,捞出,晒干;
11、黄精:洗净泥土,略润,切片,晒干;
12、紫河车:用新鲜的紫河车,横直割开血管,用水反复洗漂干净;
13、杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干;
14、太子参:摘除须根,晒干;
15、远志:拣去杂质,切段,筛去灰屑;
16、五味子:筛去灰屑,除去杂质,置蒸笼内蒸透,取出晒干;
17、蛇床子:拣去杂质,筛去泥砂,洗净,晒干;
18、金樱子:拣去杂质,切两瓣,用水稍洗泡,捞出,闷润后除去残留毛刺,挖净毛、核,干燥;
19、仙茅:取净仙茅用黄酒拌匀,润透后,置锅内微炒至干,取出,晾干,每仙茅100斤,用黄酒10-20斤;
20、补骨脂:簸尽杂质,洗净,晒干;
21、升麻:拣去杂质,略泡洗净,捞出,润透,切片,晒干;
22、柏子仁:拣净杂质,除去残留的外壳和种皮;
23、山茱萸:洗净,除去果核及杂质,晒干;
24、知母:拣净杂质,用水撞洗,捞出,润软,切片晒干;
25、王不留行:簸净杂质,置锅内,用文火炒至爆开白花六、七成时取出,放凉;
26、牛膝:拣去杂质,洗净,润软,去芦,切段,晒干。
二、制备
1、将所述重量的肉苁蓉、淫羊藿、枸杞子、鹿角胶、覆盆子、菟丝子、山药、续断、巴戟天、沙苑子、黄精、紫河车、杜仲、太子参、远志、五味子、蛇床子、金樱子、仙茅、补骨脂、升麻、柏子仁、山茱萸、知母、王不留行、牛膝放入煎药容器内,第一次加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
2、将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
3、将两次煎煮液混合搅拌均匀,分为3剂服用。
组方中覆盆子有补肝肾,缩小便,助阳,固精,明目的功能为君药;柏子仁养心安神,润肠通便;紫河车有补气,养血,益精的功能,二者为臣药,三味药共同发挥补肝肾,助阳固精,养心安神,补气养血,润肠通便的作用,治疗少精症效力全面,且以清热生津,温中行气为主可治本,山药是有健脾,补肺,固肾,益精的功能为佐药,巴戟天有补肾阳,壮筋骨,祛风湿的功能为使药,与下余诸药是治标。
本发明药物具有补肝肾,助阳固精,养心安神,补气养血,祛风湿的功能,用于治疗少精症,疗程短、见效快、治愈后不复发。
以下通过试验例来进一步阐述本发明所述药物的有益效果,这些试验例包括本发明药物的动物毒性试验报告和临床疗效观察资料。
[试验例1]本发明药物的动物毒性试验报告:
取家兔30只,雌雄兼用,体重2.0-2.5kg,分两组,每组15只,其中一组为超剂量试验组,另一组为正常量试验组。超常量组为20ml/kg,正常量为10ml/kg,给药方式为灌胃法给药,每天两次,连服7天,每天观察给药反应,结果表明二组家兔活动、饮食正常,药物无不良毒副作用。
[试验例2]本发明药物的临床疗效观察
1、一般资料
收治少精症门诊患者共25例。
2、诊断标准
典型症状为神疲乏力,腰酸膝软,头晕耳鸣,性欲淡漠等症状,亦可无任何症状,但其共同表现是婚后长期不育,精液常规精子数量少于20×10[6]/ml。
3、治疗方法
选用上述药剂,给患者服用,每次服用1剂,每天早、晚各服1次,10天为一个疗程,连续服用3个疗程。
4、疗效评定标准
显效:少精症症状消失,恢复正常,痊愈;
好转:患者神疲乏力,腰酸膝软,头晕耳鸣,性欲淡漠,精子数量少的现象减轻,少精症症状明显好转,逐步恢复正常;
无效:达不到好转标准者。
5、治疗结果(见下表)
在上述治疗中,用本发明药物治疗少精症患者25例,结果显效20例,显效率为80%,好转3例,好转率为12%,无效2例,总有效率为92%。
Claims (3)
1.一种治疗少精症的药物,其特征在于:它是由下列重量范围内的原料药制成:
肉苁蓉10-20克,淫羊藿10-20克,枸杞子10-15克,鹿角胶10-20克,覆盆子10-15克,菟丝子10-15克,山药15-20克,续断10-15克,巴戟天10-20克,沙苑子10-15克,黄精10-20克,紫河车5-15克,杜仲5-15克,太子参10-20克,远志10-15克,五味子5-15克,蛇床子5-15克,金樱子10-15克,仙茅5-10克,补骨脂10-15克,升麻5-15克,柏子仁5-15克,山茱萸5-10克,知母10-15克,王不留行10-20克,牛膝5-15克。
2.根据权利要求1所述的药物,其中各原料药的用量为:
肉苁蓉15克,淫羊藿15克,枸杞子12克,鹿角胶15克,覆盆子12克,菟丝子12克,山药18克,续断12克,巴戟天15克,沙苑子12克,黄精15克,紫河车10克,杜仲10克,太子参15克,远志12克,五味子10克,蛇床子10克,金樱子12克,仙茅8克,补骨脂12克,升麻10克,柏子仁10克,山茱萸8克,知母12克,王不留行15克,牛膝10克。
3.根据权利要求1或2所述药物的制备方法,它包括下列步骤:
(一)备料
(1)肉苁蓉:拣净杂质,清水浸泡,每天换水1-2次,如系咸苁蓉,泡尽盐分,润透,纵向切片,晒干;
(2)淫羊藿:拣净杂质,去梗,切丝,筛去碎屑;
(3)枸杞子:簸净杂质,摘去残留的梗和蒂;
(4)鹿角胶:取原药材,除去杂质,用时捣碎;
(5)覆盆子:筛去灰屑,拣净杂质,去柄;
(6)菟丝子:过箩去净杂质,洗净,晒干;
(7)山药:拣净杂质,用水浸泡至山药中心部软化为止,捞出稍晾,切片晒干或烘干;
(8)续断:洗净泥沙,除去残留根头,润透后切片晒干,筛去屑;
(9)巴戟天:拣去杂质,用热水泡透后,趁热抽去水心,切段,晒干;
(10)沙苑子:拣去杂质,漂净泥沙,捞出,晒干;
(11)黄精:洗净泥土,略润,切片,晒干;
(12)紫河车:用新鲜的紫河车,横直割开血管,用水反复洗漂干净;
(13)杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干;
(14)太子参:摘除须根,晒干;
(15)远志:拣去杂质,切段,筛去灰屑;
(16)五味子:筛去灰屑,除去杂质,置蒸笼内蒸透,取出晒干;
(17)蛇床子:拣去杂质,筛去泥砂,洗净,晒干;
(18)金樱子:拣去杂质,切两瓣,用水稍洗泡,捞出,闷润后除去残留毛刺,挖净毛、核,干燥;
(19)仙茅:取净仙茅用黄酒拌匀,润透后,置锅内微炒至干,取出,晾干,每仙茅100斤,用黄酒10-20斤;
(20)补骨脂:簸尽杂质,洗净,晒干;
(21)升麻:拣去杂质,略泡洗净,捞出,润透,切片,晒干;
(22)柏子仁:拣净杂质,除去残留的外壳和种皮;
(23)山茱萸:洗净,除去果核及杂质,晒干;
(24)知母:拣净杂质,用水撞洗,捞出,润软,切片晒干;
(25)王不留行:簸净杂质,置锅内,用文火炒至爆开白花六、七成时取出,放凉;
(26)牛膝:拣去杂质,洗净,润软,去芦,切段,晒干;
(二)制备
(1)将所述重量的肉苁蓉、淫羊藿、枸杞子、鹿角胶、覆盆子、菟丝子、山药、续断、巴戟天、沙苑子、黄精、紫河车、杜仲、太子参、远志、五味子、蛇床子、金樱子、仙茅、补骨脂、升麻、柏子仁、山茱萸、知母、王不留行、牛膝放入煎药容器内,加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
(2)将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
(3)将两次煎煮液混合搅拌均匀,分为3剂服用。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710185036.5A CN106668514A (zh) | 2017-03-25 | 2017-03-25 | 一种治疗少精症的药物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710185036.5A CN106668514A (zh) | 2017-03-25 | 2017-03-25 | 一种治疗少精症的药物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106668514A true CN106668514A (zh) | 2017-05-17 |
Family
ID=58826294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710185036.5A Pending CN106668514A (zh) | 2017-03-25 | 2017-03-25 | 一种治疗少精症的药物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106668514A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116211965A (zh) * | 2023-03-22 | 2023-06-06 | 共好发展(山东)健康科技有限公司 | 一种肾精再生修复的组合物及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105770427A (zh) * | 2016-04-24 | 2016-07-20 | 邹洪胜 | 一种治疗少精症、弱精症的中药组合物 |
-
2017
- 2017-03-25 CN CN201710185036.5A patent/CN106668514A/zh active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105770427A (zh) * | 2016-04-24 | 2016-07-20 | 邹洪胜 | 一种治疗少精症、弱精症的中药组合物 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116211965A (zh) * | 2023-03-22 | 2023-06-06 | 共好发展(山东)健康科技有限公司 | 一种肾精再生修复的组合物及其制备方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103550733A (zh) | 一种治疗滑胎的药物及其制备方法 | |
CN102631655B (zh) | 一种治疗冠心病的药物及其制备方法 | |
CN103638493B (zh) | 一种治疗男性不育的药物及其制备方法 | |
CN106668514A (zh) | 一种治疗少精症的药物及其制备方法 | |
CN103735916B (zh) | 一种治疗肾病综合症的药物及其制备方法 | |
CN103735792B (zh) | 一种治疗月经不调的药物及其制备方法 | |
CN103417893B (zh) | 一种治疗腰腿痛的药物及其制备方法 | |
CN104056224A (zh) | 一种治疗习惯性流产的药物及其制备方法 | |
CN106798857A (zh) | 一种治疗骨肿瘤的药物及其制备方法 | |
CN103638499B (zh) | 一种治疗骨关节结核的药物及其制备方法 | |
CN107029163A (zh) | 一种治疗小儿遗尿的药物及其制备方法 | |
CN106728880A (zh) | 一种治疗再生障碍性贫血的药物及其制备方法 | |
CN106177857A (zh) | 一种治疗习惯性流产的药物及其制备方法 | |
CN105396038A (zh) | 一种治疗糖尿病的药物及其制备方法 | |
CN106492125A (zh) | 一种治疗冠心病的药物及其制备方法 | |
CN105343650A (zh) | 一种治疗肾阳不足型弱精症的药物及其制备方法 | |
CN104056228A (zh) | 一种治疗小儿厌食症的药物及其制备方法 | |
CN107737300A (zh) | 一种治疗先兆流产的药物及其制备方法 | |
CN104056225A (zh) | 一种治疗心房纤颤的药物及其制备方法 | |
CN106668665A (zh) | 一种治疗功能失调性子宫出血的药物及其制备方法 | |
CN103623377B (zh) | 一种治疗痹症的药物及其制备方法 | |
CN103638466B (zh) | 一种治疗颈椎病的药物及其制备方法 | |
CN106943558A (zh) | 一种治疗死精症的药物及其制备方法 | |
CN106924584A (zh) | 一种治疗席汉综合征的药物及其制备方法 | |
CN108743902A (zh) | 一种治疗低血压的药物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170517 |
|
RJ01 | Rejection of invention patent application after publication |