CN106604733A - 利用25‑羟基维生素d的辅助疗法 - Google Patents

利用25‑羟基维生素d的辅助疗法 Download PDF

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Publication number
CN106604733A
CN106604733A CN201580047452.8A CN201580047452A CN106604733A CN 106604733 A CN106604733 A CN 106604733A CN 201580047452 A CN201580047452 A CN 201580047452A CN 106604733 A CN106604733 A CN 106604733A
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China
Prior art keywords
hydroxyvitamin
patient
composition
hypocalcemia
effective amount
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Pending
Application number
CN201580047452.8A
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English (en)
Chinese (zh)
Inventor
马丁·P·佩特科维奇
乔尔·Z·梅尔尼克
杰伊·A·怀特
萨米尔·P·塔巴什
查理斯·W·比绍夫
苏珊·H·皮尔斯
斯蒂芬·A·斯特拉格内尔
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Opko Ireland Global Holdings Ltd
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Opko Ireland Global Holdings Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53783233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106604733(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Opko Ireland Global Holdings Ltd filed Critical Opko Ireland Global Holdings Ltd
Priority to CN202210347507.9A priority Critical patent/CN114681468A/zh
Publication of CN106604733A publication Critical patent/CN106604733A/zh
Pending legal-status Critical Current

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    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
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    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
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    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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    • A61P35/04Antineoplastic agents specific for metastasis
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    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
    • AHUMAN NECESSITIES
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    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Rheumatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
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  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
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  • Botany (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201580047452.8A 2014-08-07 2015-08-06 利用25‑羟基维生素d的辅助疗法 Pending CN106604733A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210347507.9A CN114681468A (zh) 2014-08-07 2015-08-06 利用25-羟基维生素d的辅助疗法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462034604P 2014-08-07 2014-08-07
US62/034,604 2014-08-07
PCT/EP2015/068219 WO2016020508A2 (en) 2014-08-07 2015-08-06 Adjunctive therapy with 25-hydroxyvitamin d

Related Child Applications (1)

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CN202210347507.9A Division CN114681468A (zh) 2014-08-07 2015-08-06 利用25-羟基维生素d的辅助疗法

Publications (1)

Publication Number Publication Date
CN106604733A true CN106604733A (zh) 2017-04-26

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CN202210347507.9A Pending CN114681468A (zh) 2014-08-07 2015-08-06 利用25-羟基维生素d的辅助疗法
CN201580047452.8A Pending CN106604733A (zh) 2014-08-07 2015-08-06 利用25‑羟基维生素d的辅助疗法

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US (2) US20180085381A1 (enExample)
EP (1) EP3193925A2 (enExample)
JP (5) JP2017523220A (enExample)
KR (2) KR20170047265A (enExample)
CN (2) CN114681468A (enExample)
AU (2) AU2015298858A1 (enExample)
BR (1) BR112017002526A2 (enExample)
CA (1) CA2957240A1 (enExample)
CL (1) CL2017000317A1 (enExample)
CO (2) CO2018004206A2 (enExample)
CR (2) CR20170085A (enExample)
EA (1) EA201790332A1 (enExample)
EC (1) ECSP17014159A (enExample)
IL (1) IL250462A0 (enExample)
MX (1) MX2017001751A (enExample)
MY (1) MY203284A (enExample)
PE (1) PE20170392A1 (enExample)
PH (2) PH12017500228A1 (enExample)
SG (2) SG11201700858RA (enExample)
TW (2) TWI778934B (enExample)
WO (1) WO2016020508A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108519448A (zh) * 2018-04-04 2018-09-11 北京市心肺血管疾病研究所 25-羟基维生素d在制备大动脉炎患者疾病活动性评判试剂盒中的应用
CN116033940A (zh) * 2020-04-06 2023-04-28 艾尔金制药有限公司 激活内源性抗菌药物治疗sars-cov-2感染

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EP1993559B1 (en) 2006-02-03 2016-06-22 OPKO Renal, LLC Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
CA2683628C (en) 2007-04-25 2018-03-06 Cytochroma Inc. Method of treating vitamin d insufficiency and deficiency
HRP20231142T3 (hr) 2007-04-25 2024-01-05 Eirgen Pharma Ltd. Kontrolirano oslobađanje 25-hidroksivitamina d
WO2011123476A1 (en) 2010-03-29 2011-10-06 Cytochroma Inc. Methods and compositions for reducing parathyroid levels
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US10220047B2 (en) * 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
CN108883120A (zh) 2016-03-28 2018-11-23 欧普科爱尔兰环球控股有限公司 维生素d治疗方法
US20190290756A1 (en) * 2016-05-20 2019-09-26 Christoph Karl Pharmaceutical compositions with anti-rankl antibodies, calcium and vitamin d
EP3246032B1 (de) * 2016-05-20 2021-08-11 Christoph Karl Pharmazeutische zusammensetzungen mit zoledronsaeure, kalzium und vitamin d, geeignet zur behandlung und/oder prophylaxe von erkrankungen des knochenstoffwechsels und von therapiebedingten nebenwirkungen wie hypokalzaemien
CN120154576A (zh) 2018-08-31 2025-06-17 欧普科爱尔兰环球控股有限公司 儿童剂型、制造和使用方法
WO2025094144A1 (en) 2023-11-02 2025-05-08 Eirgen Pharma Ltd. Controlling loss of kidney function

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CN101668532A (zh) * 2007-04-25 2010-03-10 赛特克罗公司 治疗维生素d不足和缺乏的方法

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