CN106511868A - Medicine for treating dysuria and preparation method thereof - Google Patents

Medicine for treating dysuria and preparation method thereof Download PDF

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Publication number
CN106511868A
CN106511868A CN201611236299.6A CN201611236299A CN106511868A CN 106511868 A CN106511868 A CN 106511868A CN 201611236299 A CN201611236299 A CN 201611236299A CN 106511868 A CN106511868 A CN 106511868A
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medicine
impurity
rhizoma
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王勤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine for treating dysuria and a preparation method thereof. The medicine is mainly prepared from rhizoma dioscoreae colletii, rhizoma calami, radix linderae, rhizoma pinelliae, herba polygoni avicularis and dianthus superbus according to a certain weight proportion. The medicine has the functions of clearing away heat and toxic materials, dissolving lumps and resolving masses, and removing blood stasis and dredging meridians; when used for treating dysuria, the medicine takes effect fast, has a good treatment effect and prevents relapse.

Description

One kind treats dysuric medicine and preparation method thereof
Technical field
The present invention relates to one kind treats dysuric medicine and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Dysuria refers to that urethra has urine and discharges difficult, and the traditional Chinese medical science thinks, be as functioning of bladder is unfavorable, prevent urine from Discharge, its reason has damp and hot, accumulates many factors such as product, lung-heat with QI-obstruction, stagnation of QI due to depression of the liver, deficiency of kidney-QI and urethral obstruction and cause.Mesh Before, western medicine dysuria effect on driving birds is not good, and have more side effect, therefore, people are to the dysuric Chinese medicine of effectively treatment There is very big demand.
The content of the invention
The present inventor have found effectively treatment row finally according to the research and clinic test repeatedly and checking of theory of Chinese medical science The difficult medicine of urine, so as to complete the present invention.
It is an object of the invention to provide one kind being capable of the dysuric composition of medicine of effectively treatment.
Another object of the present invention just there is provided the preparation method of the composition of medicine.
Medicine of the present invention is to select Bi, Rhizoma Acori Calami, the Radix Linderae, the Rhizoma Pinelliae, storage, Herba Dianthi, Caulis Akebiae, Talcum, Fructus Alpiniae Oxyphyllae, Radix Glycyrrhizae What medicine was combined, cause each efficacy of drugs to produce synergism these drug regimens such that it is able to rapid, effective treatment Dysuria.Wherein it is because that its nature and flavor is bitter from Bi, puts down, enter liver, stomach, bladder warp has wind-dispelling, and the function of dampness removing controls wind Wet insensitive impediment, lumbocrural pain, dysuria, stranguria with turbid discharge, seminal emission, damp and hot sore.It is because that its nature and flavor is bitter, pungent from Rhizoma Acori Calami, tepor, Enter the heart, lung, stomach, have inducing resuscitation and resolving phlegm, ward off the function of dirty parasite killing, control sputum heap soil or fertilizer over and around the roots and close, obnubilation, chronic tracheitiss, abdominal distention abdomen Bitterly, inappetence, enteritis, dysentery, rheumatic arthralgia, wound scabies.Be because that its nature and flavor is pungent from the Radix Linderae, temperature, enter spleen, lung, kidney, Bladder warp, has pleasant, dissipating depression of QI, cold expelling, the function of pain relieving, controls QI rising in reverse order chest and abdomen swelling and pain, and dyspepsia is discontented with, and food, colic of cold type, foot are told in regurgitation Gas, frequent micturition.It is because that its nature and flavor is pungent from the Rhizoma Pinelliae, temperature is poisonous, enters spleen, stomach, has a drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, and disappear painful abdominal mass The function of eliminating stagnation, controls wet phlegm and cold drink, vomiting, regurgitation, cough and phlegm, fullness in chest, phlegm and headache, dizziness and sleepless, outer subduing inflammation. It is because that its nature and flavor is bitter from storage, trembles with fear, enter bladder warp have diuresis, pyretic stranguria, the difficulty in urination are controlled in heat clearing away, the function of parasite killing, and jaundice is cloudy Erosion, leucorrhea, ascarid, infantile malnutrition, hemorrhoid are swollen, eczema.It is because that its nature and flavor is bitter from Herba Dianthi, trembles with fear, enter the heart, kidney, small intestinal, bladder warp has Clearing away heat and promoting diuresiss, the function that removing blood stasis stimulate the menstrual flow control urinary obstruction, and gonorrhea, edema, amenorrhea, carbuncle, conjunctival congestion are hidden from view, sore of contaminating.From Caulis Akebiae is because that its nature and flavor is bitter, and cool, enter the heart, small intestinal, bladder warp have pathogenic fire purging water-filling, and the function of promoting blood circulation controls hot urination, Stranguria with turbid discharge, edema, irritable feverish sensation in the chest, larynx numbness pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasiss.Its nature and flavor is because from Talcum It is sweet, light, to tremble with fear, return bladder, lung, stomach, have inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing, the function of damp eliminating expelling summer-heat control pyretic stranguria, stranguria caused by urinary stone, and urine heat is puckery Bitterly, heat-damp in summer excessive thirst, damp and hot watery diarrhea, external treatment eczema, eczema, miliaria.It is because that its nature and flavor is pungent from Fructus Alpiniae Oxyphyllae, temperature enters spleen, kidney Jing, has warming the spleen, and warming the kidney, solid and gas, the function of arresting seminal emission control cold air stomachache, and invasion by pathogenic cold is vomited and diarrhoea, many salivas, seminal emission, and how little dribbling urination, night be Just.Its property sweet taste is because from Radix Glycyrrhizae, enters spleen, stomach, lung meridian, had and middle emergency, lung moistening, detoxified, the function of coordinating the actions of various ingredients in a prescription, Process with weakness of the spleen and stomach is controlled, lack of appetite, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, cardiopalmus shy carbuncle, raw with laryngopharynx swelling and pain is controlled, and digest Property ulcer, ulcer sores, solution poison of drug and alimentary toxicosis.
Specific embodiment
The present invention combination drug dose be also inventor through groping in a large number to summarize what is drawn, the consumption of each component is under State in weight range and all there is good therapeutic effect
Bi 10-20 gram 10-20 gram of the Radixs Linderae of 10-20 gram of Rhizoma Acori Calami
10-20 gram of the Rhizoma Pinelliae stores 5-15 gram of 5-15 gram of Herba Dianthi
5-15 gram of Caulis Akebiae 10-20 gram of Fructus Alpiniae Oxyphyllae of 5-15 gram of Talcum
10-20 gram of Radix Glycyrrhizae.
Preferable amount is
15 grams of Bi, 15 grams of Rhizoma Acori Calami, 15 grams of the Radixs Linderae
15 grams of the Rhizoma Pinelliae stores 10 grams of 10 grams of Herba Dianthis
10 grams of Caulis Akebiae, 10 grams of Talcum, 15 grams of Fructus Alpiniae Oxyphyllae
15 grams of Radix Glycyrrhizae.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Bi：Impurity is removed, section is cleaned, and immersion runs through, and is dried, weeds out chip；
2nd, Rhizoma Acori Calami：Crude drug is taken, reed clothing, impurity is removed, is cleaned, is run through, cut sheet, cold drying；
3rd, the Radix Linderae：Impurity is picked, separates size bar, noted changing water according to season, prevent smelly, pull out in time and cut with blister thoroughly Piece, weeds out grey bits；
4th, the Rhizoma Pinelliae：Impurity is picked, grey bits are weeded out；
5th, store：Impurity and root are removed, is cleaned, is softened, cutting is dried；
6th, Herba Dianthi：Net impurity is picked, undesirable root is removed, is cleaned, moistening, cutting are dried；
7th, Caulis Akebiae：Slightly soaked with water, moistening is dried to saturating, section；
8th, Talcum：Crude drug is taken, impurity, cleaning, drying are removed；
9th, Fructus Alpiniae Oxyphyllae：Take Fructus Alpiniae Oxyphyllae to put in pot, fry burned black to shell, take out cold, remove shell, take core and smash use to pieces；
10th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing.
2nd, prepare
1st, the Bi of the weight, Rhizoma Acori Calami, the Radix Linderae, the Rhizoma Pinelliae, storage, Herba Dianthi, Caulis Akebiae, Talcum, Fructus Alpiniae Oxyphyllae, Radix Glycyrrhizae medicine are put Enter in decocting container, add water for the first time 6 times and measure, after immersion 60 minutes, fry by intense fire to boil and rise, then must the with being cooked by slow fire 30 minutes Decoction liquor, first time decoction liquor is poured in container；
2nd, the medicinal residues of filtration are added water 4 times and is measured, boiled, then with being cooked by slow fire 20 minutes, second decoction liquor is poured in container；
3rd, decoction liquor will carry out mixing and stirring twice, and be divided into 3 doses and take.
Medicine of the present invention has heat-clearing and toxic substances removing, dissolving lump and resolving mass, the function that removing blood stasis stimulate the menstrual flow, for treating the dysuria course for the treatment of Short, instant effect, non-relapse after healing, have no toxic side effect.
Specific embodiment：
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include medicine of the present invention The animal toxicity test report of thing and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention：
Rabbit 30 is taken, male and female dual-purpose, body weight 2.0-2.4kg are divided to two groups, 15 per group, one of which is overdose test group, Another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is that administration by gavage is administered, Twice daily, 7 days are serve on, as a result the reaction of observation administration daily shows that two groups of rabbit activities, diet are normal, and medicine is without bad poison Side effect.
The dysuric clinical observation material of [test example 2] Drug therapy of the present invention：
1st, physical data
Accept out-patient totally 35 for medical treatment.
2nd, diagnostic criteria
Patient per's voided volume is few, and urine line attenuates, or drop and go out, or even without urine ejection.
3rd, Therapeutic Method
From above-mentioned medicament, take to patient, each take 1 dose, it is early, middle and late daily respectively to take 1 time, it is within 7 days a course for the treatment of, even It is continuous to take 2 courses for the treatment of.
4th, efficacy assessment standard
It is effective：Recovery from illness, recovers normal, and observation half a year is without recidivist；
Take a turn for the better：Urination is clearly better, and progressively recovers normal；
It is invalid：Improvement standard person is not reached.
5th, therapeutic outcome（See the table below）
In above-mentioned treatment, with Drug therapy dysuria patient of the present invention 35, as a result effective 31, obvious effective rate is 88.57%, take a turn for the better 3, improvement rate is 8.57%, and invalid 1, total effective rate is 97.14%.

Claims (3)

1. one kind treats dysuric medicine, it is characterised in that：It is made up of the crude drug in following weight range：
Bi 10-20 gram 10-20 gram of the Radixs Linderae of 10-20 gram of Rhizoma Acori Calami
10-20 gram of the Rhizoma Pinelliae stores 5-15 gram of 5-15 gram of Herba Dianthi
5-15 gram of Caulis Akebiae 10-20 gram of Fructus Alpiniae Oxyphyllae of 5-15 gram of Talcum
10-20 gram of Radix Glycyrrhizae.
2. medicine according to claim 1, wherein the consumption of each crude drug is：
15 grams of Bi, 15 grams of Rhizoma Acori Calami, 15 grams of the Radixs Linderae
15 grams of the Rhizoma Pinelliae stores 10 grams of 10 grams of Herba Dianthis
10 grams of Caulis Akebiae, 10 grams of Talcum, 15 grams of Fructus Alpiniae Oxyphyllae
15 grams of Radix Glycyrrhizae.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：
（One）Get the raw materials ready
（1）Bi：Impurity is removed, section is cleaned, and immersion runs through, and is dried, weeds out chip；
（2）Rhizoma Acori Calami：Crude drug is taken, reed clothing, impurity is removed, is cleaned, is run through, cut sheet, cold drying；
（3）The Radix Linderae：Impurity is picked, separates size bar, noted changing water according to season, prevent smelly, pull out in time and cut with blister thoroughly Piece, weeds out grey bits；
（4）The Rhizoma Pinelliae：Impurity is picked, grey bits are weeded out；
（5）Store：Impurity and root are removed, is cleaned, is softened, cutting is dried；
（6）Herba Dianthi：Net impurity is picked, undesirable root is removed, is cleaned, is stewed to moisten, cutting is dried；
（7）Caulis Akebiae：Slightly soaked with water, moistening is dried to saturating, section；
（8）Talcum：Crude drug is taken, impurity, cleaning, drying are removed；
（9）Fructus Alpiniae Oxyphyllae：Take Fructus Alpiniae Oxyphyllae to put in pot, fry burned black to shell, take out cold, remove shell, take core and smash use to pieces；
（10）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing；
（Two）Prepare
（1）By the Bi of the weight, Rhizoma Acori Calami, the Radix Linderae, the Rhizoma Pinelliae, storage, Herba Dianthi, Caulis Akebiae, Talcum, Fructus Alpiniae Oxyphyllae, Radix Glycyrrhizae medicine It is put in decocting container, adds water for the first time 6 times and measure, after soaking 60 minutes, fry by intense fire to boil and rise, then is obtained with being cooked by slow fire 30 minutes First time decoction liquor, first time decoction liquor is poured in container；
（2）The medicinal residues of filtration are added water 4 times and is measured, boiled, then with being cooked by slow fire 20 minutes, pour second decoction liquor into container It is interior；
（3）Decoction liquor will carry out mixing and stirring and obtain final product twice.
CN201611236299.6A 2016-12-28 2016-12-28 Medicine for treating dysuria and preparation method thereof Withdrawn CN106511868A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611236299.6A CN106511868A (en) 2016-12-28 2016-12-28 Medicine for treating dysuria and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201611236299.6A CN106511868A (en) 2016-12-28 2016-12-28 Medicine for treating dysuria and preparation method thereof

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104056099A (en) * 2014-06-26 2014-09-24 蔡合 Medicine for treating acute pyelonephritis and preparation method of medicine
CN106075247A (en) * 2016-07-18 2016-11-09 甄建民 A kind of medicine treating chronic urinary retention and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104056099A (en) * 2014-06-26 2014-09-24 蔡合 Medicine for treating acute pyelonephritis and preparation method of medicine
CN106075247A (en) * 2016-07-18 2016-11-09 甄建民 A kind of medicine treating chronic urinary retention and preparation method thereof

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