CN103830649A - Medicament for treating chronic alcoholism and preparation method thereof - Google Patents

Medicament for treating chronic alcoholism and preparation method thereof Download PDF

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CN103830649A
CN103830649A CN201410062962.XA CN201410062962A CN103830649A CN 103830649 A CN103830649 A CN 103830649A CN 201410062962 A CN201410062962 A CN 201410062962A CN 103830649 A CN103830649 A CN 103830649A
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CN103830649B (en
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韩非
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Abstract

The invention discloses a medicament for treating chronic alcoholism and a preparation method of the medicament. The medicament is mainly prepared from medicines such as flower of kudzu vine, fructus amomi, dried tangerine or orange peel, green soybean, ginseng, bighead atractylodes rhizome, bitter bamboo shoots, poria cocos, liquorice and chrysanthemum according to a certain weight ratio. The medicament disclosed by the invention has the functions of tonifying spleen, harmonizing stomach, clearing away heat and toxic materials, smoothening urea and moistening lung, can take effect quickly, is good in curative effect and free of side effect when used for treating chronic alcoholism.

Description

A kind of medicine for the treatment of chronic alcoholism and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of chronic alcoholism and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Chronic alcoholism (alcohol dependence disease) is that the central nervous system that causes of long-term excessive consumption of alcohol is seriously poisoning, show as the mandatory experience of craving for and often need to drinking to wine, after stopping drinking, normal sense is felt bad in the heart, is on tenterhooks, or there is limb tremor, feel sick, the abnormal symptom such as vomiting, perspiration, this class symptom of recovering to drink rapidly disappears.Owing to drinking for a long time, most bodies that merge damage, and taking the heart, liver, nervous system as obvious, modal is liver cirrhosis, peripheral neuropathy and Epileptic fits, the formation chronic alcoholic psychosis and the Chronic Alcoholic-Toxic Encephalopathy that have.Because current Western medicine cannot effectively be treated chronic alcoholism, there is great demand to the Chinese medicine of rapid, effective treatment chronic alcoholism in people therefore, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment chronic alcoholism, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment chronic alcoholism.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Flos puerariae lobatae, Fructus Amomi, Pericarpium Citri Reticulatae, Semen phaseoli radiati, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Germinatus Pleioblasti, Poria, Radix Glycyrrhizae, Flos Chrysanthemi, Radix Puerariae, Rhizoma Cimicifugae, Ganoderma, Fructus Mori, Fructus Schisandrae Chinensis, Radix Bupleuri, Fructus Amomi Rotundus, the Radix Aucklandiae, Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae Viride, Monas cuspurpureus Went, granulated sugar, selenium, vitamin B1, vitamin B6 medicine to combine preparation, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat chronic alcoholism.Wherein select Flos puerariae lobatae to be because its nature and flavor are sweet, cool, enter sufficient Yangming Channel, have the function of relieving acute alcoholism and recuperating the spleen, the wine that cures the wound heating, excessive thirst, anorexia, vomiting acid regurgitation, spits blood, discharging fresh blood stool.Select Fructus Amomi to be because its nature and flavor are pungent, temperature, enters spleen, stomach warp, has in circulation of qi promoting tune, and stomach function regulating, the function of being amusing, control stomachache painful abdominal mass swollen, and anorexia dyspepsia, chokes every vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.Selecting Pericarpium Citri Reticulatae is that temperature, returns lung, spleen channel, has regulating qi-flowing for strengthening spleen because of its nature and flavor hardship, pungent, and the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select Semen phaseoli radiati to be because its nature and flavor are sweet cool, enter the heart, stomach warp, have heat-clearing and toxic substances removing, relieve summer heat, the function of diuretic, controls summer-heat excessive thirst, and edema, rushes down profit, erysipelas, carbuncle, antipyretic poison of drug.Select Radix Ginseng to be because its nature and flavor are sweet micro-sweet, temperature, enters spleen, lung meridian, has strongly invigorating primordial QI, Gu promote the production of body fluid de-, the function of calming the nerves, controls impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, empty cough with asthma is short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.Select Germinatus Pleioblasti to be because its property bitter but sweet flavor is cold, have heat clearing away, dehumidifying, diuretic, sharp object function, controls and quenches one's thirst, appearance Huang, beriberi.Select Poria to be because its property slightly sweet flavor is flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, controls dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Select Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, processs use, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus , Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, and ulcer sores, separates poison of drug and alimentary toxicosis.Select Flos Chrysanthemi to be because its nature and flavor sweetness and bitterness is cool, enter lung, Liver Channel, has dispelling wind, the heat that disappears, and improving eyesight, the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, there is yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is quenched the thirst, cures the wound cold, warm, headache, stiffness of the nape, dysphoria with smothery sensation disappears and drinks, has loose bowels, dysentery, abnormal pigmentary deposit on the skin is examined not saturating, hypertension, angina pectoris, deafness.Select Rhizoma Cimicifugae to be because the sweet pungent micro-hardship of its nature and flavor is cool, enter lung, spleen, stomach warp, have yang invigorating, deliver rash, the function of removing toxic substances, controls seasonal epidemic pathogens epidemic disease labor, headache cold and heat, and laryngalgia, aphtha scar, macule is not saturating, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women's metrorrhagia and leukorrhagia, uterus tenesmus, carbuncle sore tumefacting virus.Select Ganoderma lucidum seu Japonicum to be because its nature and flavor are sweet, flat, control asthenia, cough, asthma, insomnia, dyspepsia.Select Fructus Mori to be because its nature and flavor are sweet, cold, enter liver, kidney channel, has tonifying liver, and kidney tonifying relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows the function of liquid, controls hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Selecting Fructus Schisandrae Chinensis is that temperature, enters lung, kidney channel, astringes the lung because of its nature and flavor acid, and nourishing kidney, promotes the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Select Radix Bupleuri to be because its nature and flavor hardship is cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.Select Fructus Amomi Rotundus be because its nature and flavor pungent, temperature, enters lung, spleen channel, has sector-style, warming the stomach, helps digestion, the function of alleviating distention in middle-JIAO, controls the stagnation of QI, dyspepsia is uncomfortable in chest, abdominal distention, eructation, dysphagic, tell contrary, regurgitation, malaria.Select the Radix Aucklandiae to be because its nature and flavor are arduous, temperature, enters lung, liver, spleen channel, has promoting the circulation of QI to relieve pain, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and vomiting, has loose bowels, dysentery tenesmus, colic of cold type.Select Exocarpium Citri Rubrum to be because its nature and flavor are arduous, temperature, enters brothers' sun, the sun, Yangming Channel, has expectorant, promoting the circulation of QI, and alleviating distention in middle-JIAO, the function of eliminating stagnation, controls wind and cold phlegmatic cough, feels sick, guttation, chest pain feeling of distension and oppression.Selecting Pericarpium Citri Reticulatae Viride is that tepor, enters liver, gallbladder meridian, has soothing the liver dispelling the stagnated QI because of its nature and flavor toil, and the function of eliminating stagnation expectorant is controlled breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction piece.Select Monas cuspurpureus Went to be because it is sweet in flavor and warm in property, have blood circulation promoting and blood stasis dispelling, the function of strengthening the spleen to promote digestion, controls the stagnant stomachache of the stasis of blood, and food stagnation is glutted, red white dysentery, traumatic injury.Select granulated sugar to be because it is sweet in flavor and cold in property, have profit cardiopulmonary, deinebriating function, controls trusted subordinate's flatulence of heat type, intestine and small intestine heat.Select selenium, selenium is a kind of chemical element, and chemical symbol is Se, a kind of nonmetal.Can be used as useful nutrient of the essential nutrient of light-sensitive material, electrolytic manganese industry catalyst, animal body and plant etc.Selenium is respectfully called " kindling material of life " by domestic and international the world of medicine and nutrition educational circles, enjoys the good reputation such as " long-lived element ", " anticancer king ", " heart patron saint " " natural antidote ".Selenium is 1/10000000th at tissue intensive amount, but it has determined the existence of life, is that other materials are irreplaceable to the great function of human health.Scarce selenium can directly cause human body immunity to decline, clinical medicine proves, threaten 40 various diseases of human health and life all relevant with the scarce selenium of human body, as cancer, cardiovascular diseases, hepatopathy, cataract, pancreas disease, diabetes, reproductive system disease etc.According to expert's textual criticism, people needs lifelong selenium supplement.No matter be zoopery or clinical practice, the selenium that should constantly obtain q.s from diet has all been described, can not supplement in time, will reduce the ability of getting rid of illness.Select vitamin B1, claim again thiamine or antineuritic vitamin or anti beriberi vitamin, molecular formula: C12H16N4OS(HCl), be in vitamin, to find one the earliest.A kind of vitamin B group being combined into by methylene by pyrimidine ring and thiazole ring.For white crystals or crystalline powder; Can help digest, particularly the digestion of carbohydrate; Can improve mental status; Maintain the normal of nervous tissue, muscle, cardiomotility; Alleviate airsick, seasick.Select vitamin B6; vitamin B6 (Vitamin B6) claim again pyridoxin; it comprises pyridoxol, 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine. and pyridoxamine; vitamin B6 is the constituent of some coenzyme in human body; participate in multiple metabolic response; especially there is substantial connection with amino acid metabolism; apply clinically Vitamin B6 preparation control vomiting during pregnancy and radiation sickness vomiting; vitamin B6 has protection vascular endothelial cell; reduce the effect that endotheliocyte is subject to activated blood platelet damage; suppress the effect of platelet aggregation and blood coagulation, vitamin b6 is body fat and glycometabolic essential material.
Detailed description of the invention
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight.
Flos puerariae lobatae 10-20 gram of Fructus Amomi 5-15 gram of Pericarpium Citri Reticulatae 4-12 gram
Semen phaseoli radiati 15-25 gram of Radix Ginseng 10-18 gram of Rhizoma Atractylodis Macrocephalae 5-10 gram
Germinatus Pleioblasti 4-10 gram of Poria 10-20 gram of Radix Glycyrrhizae 5-10 gram
Flos Chrysanthemi 8-15 gram of Radix Puerariae 2-8 gram liter fiber crops 2-6 gram
Ganoderma 2-6 gram of Fructus Mori 15-25 gram of Fructus Schisandrae Chinensis 2-6 gram
Radix Bupleuri 8-15 gram of Fructus Amomi Rotundus 15-25 gram of Radix Aucklandiae 0.5-5 gram
Exocarpium Citri Rubrum 4-10 gram of Pericarpium Citri Reticulatae Viride 5-15 gram of Monas cuspurpureus Went 4-8 gram
Granulated sugar 15-25 gram of selenium 15-25 microgram vitamin B1 15-25 milligram
Vitamin B6 15-25 milligram.
Be preferably:
6 grams of 6 grams of Pericarpium Citri Reticulataes of 15 grams of Fructus Amomis of Flos puerariae lobatae
6 grams of 15 grams of Rhizoma Atractylodis Macrocephalaes of 20 grams of Radix Ginsengs of Semen phaseoli radiati
6 grams, 15 grams of Radix Glycyrrhizaes of 6 grams of Poria of Germinatus Pleioblasti
3 grams of 10 grams of Radix Puerariaes of Flos Chrysanthemi, 3 gram liter fiber crops
3 grams of 20 grams of Fructus Schisandrae Chinensis of 3 grams of Fructus Moris of Ganoderma
1 gram of 20 grams of Radix Aucklandiae of 10 grams of Fructus Amomi Rotunduss of Radix Bupleuri
5 grams, 10 grams of Monas cuspurpureus Went of 5 grams of Pericarpium Citri Reticulatae Virides of Exocarpium Citri Rubrum
20 milligrams of 20 grams of selenium of granulated sugar, 20 microgram vitamin B1s
20 milligrams of vitamin Bies.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Flos puerariae lobatae: choose handle and impurity, sieve removes soil;
2, Fructus Amomi: choose decontamination and shell, smash to pieces;
3, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dries or cold drying, sieve dedust bits;
4, Semen phaseoli radiati: get crude drug, remove impurity;
5, Radix Ginseng: except removing LU, cutting;
6, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
7, Germinatus Pleioblasti: remove impurity, dry;
8, Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
9, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, airing;
10, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
11, Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, section, dries in time;
12, Rhizoma Cimicifugae: choose decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
13, Ganoderma: remove impurity, clean, soften, cut sheet, dry, sieve removes chip;
14, Fructus Mori: wash, choose decontamination, extract long handle, dry;
15, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
16, Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through rear timely section, dry;
17, Fructus Amomi Rotundus: choose clean impurity, sieve scurf removing, smashes, or peel off shell, gets core and smashes use;
18, the Radix Aucklandiae: crude drug in whole is put in clear water and cleaned, pull out, moistening 12-24 hours, section, dries;
19, Exocarpium Citri Rubrum: choose decontamination, outwash, used time folding is broken;
20, Pericarpium Citri Reticulatae Viride: choose clean impurity, be soaked in water, pull out, run through, section, dries;
21, Monas cuspurpureus Went: well sifted ash bits, choose decontamination;
22, granulated sugar: extract according to quantity;
23, selenium: extract according to quantity;
24, vitamin B1: extract according to quantity;
25, vitamin B6: extract according to quantity.
Two, preparation
1, the Flos puerariae lobatae of described weight, Fructus Amomi, Pericarpium Citri Reticulatae, Semen phaseoli radiati, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Germinatus Pleioblasti, Poria, Radix Glycyrrhizae, Flos Chrysanthemi, Radix Puerariae, Rhizoma Cimicifugae, Ganoderma, Fructus Mori, Fructus Schisandrae Chinensis, Radix Bupleuri, Fructus Amomi Rotundus, the Radix Aucklandiae, Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae Viride are decocted with water twice, 6 times of amounts for the first time add water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time.
2, the medicinal residues after filtering are for the first time added water 4 times and measured, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time.
3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, then adds Monas cuspurpureus Went, granulated sugar, selenium, vitamin B1, the vitamin B6 mixing and stirring of described weight and get final product, and medicinal liquid is divided into two doses and takes.
Medicine of the present invention has strengthening the spleen stomach function regulating, heat-clearing and toxic substances removing, and the function of diuretic lung moistening, is used for the treatment of chronic alcoholism instant effect, good effect, has no side effect.
Further set forth below the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit activities, diet are normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
(1) have for a long time or history of drinking history repeatedly, symptom deducibility causes because drinking.
(2) wine is had to strong craving for.
(3) have one of following situation at least, stop drinking can there is limb tremor, cathisophobia, feel sick, vomiting, profuse sweating or the unusual symptom such as easily enrage; Continue to drink and can avoid the appearance of unusual symptom, often drink or frequently drink with wine early morning; Repeatedly attempt alleviating alcohol addiction failure; Ethanol is produced to toleration, and drinking amount increases; Abandon other recreations or hobby for drinking.Must note getting rid of other physical diseases, especially Psychoactive Substance Dependence, affective disorders are as depression and anxiety neurosis etc.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, every day 2 times, each 1 dose 15 days is a course for the treatment of, takes continuously 2 courses for the treatment of.
4, efficacy assessment standard
Effective: the recovery from illness of chronic alcoholism symptom, recovers normal;
Take a turn for the better: chronic alcoholism symptom alleviates, progressively take a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
Figure 637554DEST_PATH_IMAGE002
In above-mentioned treatment, by Drug therapy chronic alcoholism patient of the present invention 100 examples, effective 83 examples of result, obvious effective rate is 83%, 12 examples that take a turn for the better, and improvement rate is 12%, invalid 5 examples, total effective rate is 95%.

Claims (3)

1. a medicine for the treatment of chronic alcoholism, is characterized in that: it is to be made up of the crude drug in following weight range:
Flos puerariae lobatae 10-20 gram of Fructus Amomi 5-15 gram of Pericarpium Citri Reticulatae 4-12 gram
Semen phaseoli radiati 15-25 gram of Radix Ginseng 10-18 gram of Rhizoma Atractylodis Macrocephalae 5-10 gram
Germinatus Pleioblasti 4-10 gram of Poria 10-20 gram of Radix Glycyrrhizae 5-10 gram
Flos Chrysanthemi 8-15 gram of Radix Puerariae 2-8 gram liter fiber crops 2-6 gram
Ganoderma 2-6 gram of Fructus Mori 15-25 gram of Fructus Schisandrae Chinensis 2-6 gram
Radix Bupleuri 8-15 gram of Fructus Amomi Rotundus 15-25 gram of Radix Aucklandiae 0.5-5 gram
Exocarpium Citri Rubrum 4-10 gram of Pericarpium Citri Reticulatae Viride 5-15 Monas cuspurpureus Went 4-8 gram
Granulated sugar 15-25 gram of selenium 15-25 microgram vitamin B1 15-25 milligram
Vitamin B6 15-25 milligram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
6 grams of 6 grams of Pericarpium Citri Reticulataes of 15 grams of Fructus Amomis of Flos puerariae lobatae
6 grams of 15 grams of Rhizoma Atractylodis Macrocephalaes of 20 grams of Radix Ginsengs of Semen phaseoli radiati
6 grams, 15 grams of Radix Glycyrrhizaes of 6 grams of Poria of Germinatus Pleioblasti
3 grams of 10 grams of Radix Puerariaes of Flos Chrysanthemi, 3 gram liter fiber crops
3 grams of 20 grams of Fructus Schisandrae Chinensis of 3 grams of Fructus Moris of Ganoderma
1 gram of 20 grams of Radix Aucklandiae of 10 grams of Fructus Amomi Rotunduss of Radix Bupleuri
5 grams, 10 grams of Monas cuspurpureus Went of 5 grams of Pericarpium Citri Reticulatae Virides of Exocarpium Citri Rubrum
20 milligrams of 20 grams of selenium of granulated sugar, 20 microgram vitamin B1s
20 milligrams of vitamin Bies.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Flos puerariae lobatae: choose handle and impurity, sieve removes soil;
(2) Fructus Amomi: choose decontamination and shell, smash to pieces;
(3) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dries or cold drying, sieve dedust bits;
(4) Semen phaseoli radiati: get crude drug, remove impurity;
(5) Radix Ginseng: except removing LU, cutting;
(6) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(7) Germinatus Pleioblasti: remove impurity, dry;
(8) Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
(9) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, airing;
(10) Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
(11) Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, section, dries in time;
(12) Rhizoma Cimicifugae: choose decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
(13) Ganoderma: remove impurity, clean, soften, cut sheet, dry, sieve removes chip;
(14) Fructus Mori: wash, choose decontamination, extract long handle, dry;
(15) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
(16) Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through rear timely section, dry;
(17) Fructus Amomi Rotundus: choose clean impurity, sieve scurf removing, smashes, or peel off shell, gets core and smashes use;
(18) Radix Aucklandiae: crude drug in whole is put in clear water and cleaned, pull out, moistening 12-24 hours, section, dries;
(19) Exocarpium Citri Rubrum: choose decontamination, outwash, used time folding is broken;
(20) Pericarpium Citri Reticulatae Viride: choose clean impurity, be soaked in water, pull out, run through, section, dries;
(21) Monas cuspurpureus Went: well sifted ash bits, choose decontamination;
(22) granulated sugar: extract according to quantity;
(23) selenium: extract according to quantity;
(24) vitamin B1: extract according to quantity;
(25) vitamin B6: extract according to quantity;
(2) preparation
(1) Flos puerariae lobatae of described weight, Fructus Amomi, Pericarpium Citri Reticulatae, Semen phaseoli radiati, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Germinatus Pleioblasti, Poria, Radix Glycyrrhizae, Flos Chrysanthemi, Radix Puerariae, Rhizoma Cimicifugae, Ganoderma, Fructus Mori, Fructus Schisandrae Chinensis, Radix Bupleuri, Fructus Amomi Rotundus, the Radix Aucklandiae, Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae Viride are decocted with water twice, 6 times of amounts for the first time add water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time;
(2) medicinal residues after filtering are for the first time added water 4 times and measured, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time;
(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, then adds Monas cuspurpureus Went, granulated sugar, selenium, vitamin B1, the vitamin B6 mixing and stirring of described weight and get final product, and medicinal liquid is divided into two doses and takes.
CN201410062962.XA 2014-02-22 2014-02-22 A kind of medicine for the treatment of chronic alcoholism and preparation method thereof Expired - Fee Related CN103830649B (en)

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CN104288652A (en) * 2014-10-15 2015-01-21 圣原健康产业有限公司 Traditional Chinese medicine composition with hangover-alleviating health care effect and preparation method and application of traditional Chinese medicine composition

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CN102038260A (en) * 2010-11-09 2011-05-04 万光瑞 Chinese medicinal alcoholism relieving health-care beverage and preparation method thereof
CN102178885A (en) * 2011-04-29 2011-09-14 肇庆学院 Medicinal composition for sobering

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CN102038260A (en) * 2010-11-09 2011-05-04 万光瑞 Chinese medicinal alcoholism relieving health-care beverage and preparation method thereof
CN102178885A (en) * 2011-04-29 2011-09-14 肇庆学院 Medicinal composition for sobering

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288652A (en) * 2014-10-15 2015-01-21 圣原健康产业有限公司 Traditional Chinese medicine composition with hangover-alleviating health care effect and preparation method and application of traditional Chinese medicine composition

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