CN106509659A - Struthio camelus bone sugarless tablets as well as preparation method and application thereof - Google Patents
Struthio camelus bone sugarless tablets as well as preparation method and application thereof Download PDFInfo
- Publication number
- CN106509659A CN106509659A CN201610925182.2A CN201610925182A CN106509659A CN 106509659 A CN106509659 A CN 106509659A CN 201610925182 A CN201610925182 A CN 201610925182A CN 106509659 A CN106509659 A CN 106509659A
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- ostrich
- oil
- bone
- blood
- muscle
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Classifications
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- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The invention discloses struthio camelus bone sugarless tablets. The struthio camelus bone sugarless tablets comprise the following effective components in percentage by weight: 30-70% of struthio camelus bones, 10-30% of struthio camelus tendons, 10-30% of struthio camelus blood, 0.3-3% of struthio camelus oil, 10-30% of dextrin, 20-40% of xylitol, 1-5% of vitamin C, 0.01-0.2% of stevioside and 0.01-1% of mint oil. The struthio camelus bone sugarless tablets disclosed by the invention do not need to be brewed, are small in size, convenient to carry, good and adjustable in mouth feel, quick to absorb and stable in quality, the validity period is effectively prolonged, and the health-care efficacies of the struthio camelus bones are conveniently and effectively exerted.
Description
Technical field
The invention belongs to sugar-free tablet manufacture technology field, is related to a kind of ostrich bone sugar-free tablet and its preparation method and application.
Background technology
African Ostrich (Struthio camelus) is distributed mainly on Sahara south, American-European, emu
Build is smaller with respect to African Ostrich, and disposition is docile, but they all possess the large body of strong length and leg muscle group, and which is run quickly
Run speed per hour and be close to 100 kilometers.In the nineties in 20th century, China starts to introduce Ostrichs breeing technology, carries out industrialization development, nowadays
China has become the fifth-largest Ostrichs breeing state in the Asia first, world.Its product mainly includes ostrich meat, skin, egg and feather etc., is
Luxury food, famous and precious leather, handicraft, the important sources of ornament materials.Ostrich whole body is all treasured, such as：Ostrich oil derives from ostrich
Bird fat, is tasteless, odorless, slightly flaxen oily liquids, and freezing point is low, good stability, moistness is excellent, moisture retention is high,
Permeability is strong, mainly puts acid, palm fibre by oleic acid, palm fibre and puts the fitter acids and its ester class such as oleic acid, linoleic acid and stearic acid and constitutes, and which is unique
Aliphatic acid composition it is similar to the aliphatic acid of human body skin composition, and in ostrich oil, do not contain phosphatide, contain it is various can pain relieving, disappear
Scorching, sterilized low-carbon (LC) alcohols and mono fatty acid glyceride etc. and with abundant vitamin A. D. E, K etc..Ostrich oil not only may be used
Make the cosmetics of super quality, and can pain relieving, anti-inflammatory, unfold muscles and bones, repair cell, wound healing, the living burn and scald and right treated
Aseptic skeletal diseases and protection angiocarpy etc. have positive effect.Ostrich oil has extremely in cosmetics and health care industry
It is widely applied prospect.Such as：Ostrich bone contains abundant calcareous, is calcium in natural calcium, and the green plant-eating animal bone of category, composition are closed
Reason, balanced, various useful element contents equilibriums.Wherein the content of calcium is 24.33-28.03 %, and the content of phosphorus is 9.51-
10.19%, magnesium：1.1g/kg, iron：66.29mg/kg, copper：7.0mg/kg, zinc：1.33mg/kg, selenium：0.04mg/kg, and it is poisonous
National standard is far below if harmful substance such as lead, arsenic, mercury content.For another example：Muscle broad sense refer to muscle tendon ligament manadesma stndon sheath,
Synovial bursa, capsular ligament, nerve and blood vessel, or even articular cartilage, ambo etc., narrow sense refers to tendon ligament, rich in collagen,
Soreness and weakness of waist and knees, muscles and bones weakness, trick cramp, lumbar vertebrae pain, anaemia palpitaition to people, limbs are tired, joint varicose is ineffective etc. has
Good dietary function.As can be seen from the above ostrich iliacus blood oil has the benefits such as health-care effect to human body, but at present to ostrich
The utilization of bird is insufficient, and ostrich iliacus blood oil is often dropped waste, while also not having a kind of adaptation modern society's life on market
The ostrich bone health care preparation of rhythm, can be convenient for carrying for people and safety clothes.
The content of the invention
It is an object of the invention to provide a kind of ostrich bone sugar-free tablet, need not brew, compact is easy to carry, by ostrich
Bone need not be brewed, compact is easy to take by traditional edible new paragon sugar-free tablet for being transformed into and facilitating modern to take of stewing soup
Band, mouthfeel are good, absorb fast, steady quality, and extension of validity more conveniently and efficiently plays ostrich bone health-care efficacy.
The present invention is adopted the following technical scheme that：
Ostrich bone 30%-70%, ostrich muscle 10%-30%, ostrich blood 10%-30%, ostrich oil 0.3%-3%, dextrin 10%-30%, wood sugar
Alcohol 20%-40%, vitamin C 1%-5%, stevioside 0.01%-0.2%, peppermint oil 0.01-1%.
It is a further object to provide the preparation method of ostrich bone sugar-free tablet:
Step 1, ostrich bone is crushed, and is sieved, and makes ostrich bone meal;
Step 2, takes ostrich muscle and ostrich blood, smashes, put jacketed stainless cylinder of steel, add water, Jing after compound ferment treatment, hydrolyzate
Filter, filtrate is spray-dried and makes ostrich muscle blood polypeptide powder;
Step 3, the preparation method of ostrich oil is:With ostrich adipose tissue as raw material, smash, be placed in extraction element, add water and carry
Take, be layered, separation of oil filters to obtain ostrich crude oil;By ostrich crude oil heating and melting, weak caustic solution is added, is stirred evenly, be layered, collected
Oil phase processed, obtains ostrich oil.Or with ostrich adipose tissue as raw material, smash, it is placed in extraction element, adds water, adds
Dilute alkaline soln, stirring, layering are collected oil phase dehydration, obtain ostrich oil.
Step 4, by ostrich bone meal, ostrich muscle blood polypeptide powder, ostrich oil, vitamin C, peppermint oil, dextrin, xylitol, sweet
Chrysanthemum glycosides mixing granulation;
Step 5, it is grain is compressing and pack.
Ostrich polypeptide powder preparation process in the step 2：By ostrich muscle and ostrich blood, temperature control type jacketed stainless steel is put anti-
Answer tank, by the compound enzyme for having activated, between 1%-10%, pH value is 6.0-8.0 to enzyme bottom ratio, 40-60 DEG C be incubated 2 hours-
6 hours, hydrolysis, hydrolyzate were filtered, and filtrate is spray-dried and makes ostrich muscle blood polypeptide powder, its purity range 60%-80%.It is compound
Enzyme：Plant rennet is (such as：Bromelain, papain etc.), animal protease（Such as：Trypsase, pepsin etc.）、
Microbial protease is (such as：Obtained by the fermented extraction such as bacillus subtilis, actinomyces, aspergillus terricola）；Neutral proteinase is again
Claim serrapeptass, obtained by the fermented extraction of bacillus subtilis；Polypeptidase etc., takes two of which or three kinds are matched somebody with somebody by proper proportion
5 combine, for example：Papain:Neutral proteinase:Polypeptidase=21:12:9.Activation method：Compound enzyme 100mg adds
Enter 10mL-30mL1%-2% NaCI solution, 35 DEG C -45 DEG C, be incubated -2 hours 0.5 hour.
Ostrich oil preparation process in the step 3：（1）Ostrich adipose tissue is taken, is smashed, put in extraction element, add 2-
10 times of amount water are extracted 1-2 time, and -2 hours 1 hour each extraction time, Extracting temperature are 80 DEG C -130 DEG C, and extract is filtered, filter
Liquid separates oil phase and obtains ostrich oil in 25 DEG C of -75 DEG C of stratification.(2) or ostrich adipose tissue is taken, smashes, put extraction element
In, adding 2-10 times to measure water and extract 1-2 time, -2 hours 1 hour each extraction time, Extracting temperature are 80 DEG C -130 DEG C, are extracted
Liquid is filtered, and filtrate separates oil phase homogeneous heating and melts, add 1%-10% weak caustic solutions, stir in 25 DEG C of -75 DEG C of stratification,
In 25 DEG C of -75 DEG C of stratification, collect oil phase and obtain ostrich oil.（3）Or ostrich adipose tissue is taken, smash, put in extraction element,
Add 2-10 times to measure water to extract 1-2 time, -2 hours 1 hour each extraction time, Extracting temperature are 80 DEG C -130 DEG C, are added
1%-10% weak caustic solutions, stirring are filtered, and filtrate filtrate separates oil phase and obtains ostrich oil in 25 DEG C of -75 DEG C of stratification.
The present invention also provides a kind of purposes of above-mentioned ostrich bone sugar-free tablet, and its purposes is：
Effect：Can supplement abundant amino acid, polypeptide, low-carbon (LC) alcohols and mono fatty acid glyceride and vitamin A. D. E, K etc.,
The various trace elements such as human body readily absorbable calcium and phosphorus, magnesium, iron, copper, zinc, selenium, have tonifying Qi, qi-restoratives, beneficial blood, hypoglycemic, enhancing bone close
Spend, stimulate the circulation of the blood and cause the muscles and joints to relax, improve exercise tolerance, anti-injury gained in sports, it is antifatigue, improve sexual function, strengthen immunity, anti-ageing wait for a long time significantly
Effect.
Clinical practice：Can be used for anti-treating rheumatic arthritis, arteriosclerosis and obstruction of lower limbs, scapulohumeral periarthritis, osteoporosis, malignant tumour and glycosuria
Disease etc., it can also be used to which beauty moisturizing, teenager are built up health, move personage's raising device endurance etc..
Using method：Orally：One time 1～3, daily 1～3 time；Or follow the doctor's advice.
The term of validity：2 years.
Beneficial effects of the present invention are embodied in:
1. ostrich bone edible is transformed to facilitate modern to take new by traditional stewing soup by the ostrich bone sugar-free tablet of the present invention
Mode sugar-free tablet, compact are easy to carry, and mouthfeel is good and adjustable, absorb fast, and steady quality, extension of validity are more convenient to have
The health-care efficacy of ostrich bone has been played effect.
2. the ostrich bone sugar-free tablet of the present invention makes full use of ostrich resource, comprehensive utilization ostrich iliacus blood oil, it is to avoid ostrich
The waste of bird iliacus blood oil, increases ostrich in industrial added value.
3. the ostrich bone sugar-free tablet of the present invention, constitutes new working substance basis, expands purposes, and the scope of application is wider, should
It is more preferable with effect.Natural collagen protein Jing after protease hydrolytic can obtain adjusting with anti-oxidant, lowering blood pressure and blood fat, immunity
The polypeptide of the physiological regulation function such as section, hormone control, antifatigue, which is the function factor of great development prospect, and current doctor
One of most popular research topic of medicine, food circle.Polypeptide is the compound that a-amino acid is formed so that peptide bond links together,
It is the intermediate product of protein hydrolysis, is generally formed by three or more than three amino acid molecular dehydrating condensations.Polypeptide is easily by people
Body directly absorbs modification and utilizes, and plays the part of role of crucial importance in human body various functions normal course of operation, and polypeptide has collagen many
Peptide, antibacterial polypeptide, cell factor simulating peptide, cholesterol peptide, the peptide (CPPS) for promoting mineral absorption, enzyme adjustment agent are (as promoted pancreas
BPTI), Hormone Peptide such as somatotropin releasing factor (GRFS), albumin insulin synergy peptide, antibacterial polypeptide is (such as streptococcus lactis
Element, dambonite), anticancer polypeptide (such as tumor necrosis factor alpha, ring peptide), anti-AIDS peptide (such as GLQ albumen) etc..The present invention
The ostrich oil obtained from ostrich adipose tissue mainly by oleic acid, palm fibre put acid, palm fibre put the aliphatic acid such as oleic acid, linoleic acid and stearic acid and
Its esters is constituted, and its unique aliphatic acid composition is similar to the aliphatic acid of human body skin composition, alcohols containing low-carbon (LC) and mono fatty acid
Glyceride etc. and with abundant vitamin A. D. E, K etc.；Aliphatic acid in the case where there is sufficient oxygen supply, oxidable decomposition
For CO2And H2O, discharges big energy, becomes one of body main energy sources；Infiltration of the aliphatic acid to human body skin and tissue
Power and to take medicine ability relatively strong, therefore the ostrich bone sugar-free tablet of the present invention can supplement abundant amino acid, polypeptide, low-carbon (LC) alcohols and list
The lot of trace such as fatty glyceride and vitamin A. D. E, K etc., human body readily absorbable calcium and phosphorus, magnesium, iron, copper, zinc, selenium unit
Element, have tonifying Qi, qi-restoratives, beneficial blood, hypoglycemic, strengthen bone density, stimulate the circulation of the blood and cause the muscles and joints to relax, improve exercise tolerance, anti-injury gained in sports, it is antifatigue,
Improve sexual function, strengthen immunity, anti-ageing remarkable effect of waiting for a long time.The scope of application is wider, and application effect preferably, can be used to prevent and treat wind
Wet arthritis, arteriosclerosis and obstruction of lower limbs, scapulohumeral periarthritis, osteoporosis, malignant tumour and diabetes etc., it can also be used to beauty moisturizing, teenager
Build up health, move personage's raising device endurance etc..
4. the ostrich bone sugar-free tablet of the present invention is advanced quick with production technology, easy to be controllable, and environmental protection is without any pollution, energy
Consumption is relatively low, and yield is higher, stable, safe and efficient, and being very suitable for industrial enterprise carries out large-scale production application and whole-process control product
Quality.
Specific embodiment：
Embodiment 1
Ostrich bone 30%, ostrich muscle 10%, ostrich blood 10%, ostrich oil 0.3%, dextrin 10%, xylitol 20%, vitamin C 1%, stevia rebaudianum
Glycosides 0.01%, peppermint oil 0.01.
Embodiment 2
Ostrich bone 70%, ostrich muscle 30%, ostrich blood 30%, ostrich oil 3%, dextrin 30%, xylitol 40%, vitamin C 5%, stevioside
0.2%th, peppermint oil 1%.
Embodiment 3
Ostrich bone 50%, ostrich muscle 30%, ostrich blood 10%, ostrich oil 1%, dextrin 30%, xylitol 20%, vitamin C 3%, stevioside
0.1%th, peppermint oil 0.05%.
Embodiment 4
Ostrich bone 30%, ostrich muscle 30%, ostrich blood 30%, ostrich oil 2%, dextrin 15%, xylitol 30%, vitamin C 1%, stevioside
0.2%th, peppermint oil 1%.
Embodiment 5
Preparation method：
Step 1, ostrich bone is crushed, and is sieved, and makes ostrich bone meal；
Step 2, by ostrich muscle and ostrich blood, puts temperature control type jacketed stainless steel reaction tank, by the bromelain for having activated,
Enzyme bottom ratio is 1%, and pH value is 6.0,40 DEG C and is incubated 2 hours, and hydrolysis, hydrolyzate are filtered, and filtrate is spray-dried and makes ostrich muscle blood
Polypeptide powder.Activation method：Bromelain 100mg adds 10mL1% NaCI solution, and 35 DEG C are incubated 0.5 hour.
Step 3, the preparation method of ostrich oil is：（1）Ostrich adipose tissue is taken, is smashed, put in extraction element, add 2 times
Amount water is extracted 1 hour, and Extracting temperature is 80 DEG C, and extract is filtered, and filtrate separates oil phase and obtains ostrich oil in 25 DEG C of stratification.
Step 4, by ostrich bone meal, ostrich muscle blood polypeptide powder, ostrich oil, vitamin C, peppermint oil, dextrin, xylitol, sweet
Chrysanthemum glycosides mixing granulation；
Step 5, it is grain is compressing and pack.
Embodiment 6
Step 1, ostrich bone is crushed, and is sieved, and makes ostrich bone meal；
Step 2, by ostrich muscle and ostrich blood, puts temperature control type jacketed stainless steel reaction tank, by the trypsase for having activated, enzyme
Bottom is 10%, and pH value is 8.0,60 DEG C and is incubated 6 hours, and hydrolysis, hydrolyzate are filtered, and filtrate is spray-dried and makes ostrich muscle blood polypeptide
Powder.Activation method：Compound enzyme 100mg adds 30mL2% NaCI solution, 45 DEG C, is incubated 2 hours.
Step 3, the preparation method of ostrich oil is：Ostrich adipose tissue is taken, is smashed, put in extraction element, add 10 times of bodies
The water of product weight ratio is extracted 2 times, and 2 hours each extraction times, Extracting temperature are 130 DEG C, and extract is filtered, and filtrate is quiet in 75 DEG C
Layering is put, oil phase homogeneous heating is separated and is melted, add 10% weak caustic solution, stirring in 75 DEG C of stratification, to collect oil phase and obtain ostrich
Bird oil.
Claims (5)
1. a kind of ostrich bone sugar-free tablet, it is characterised in that be prepared by the raw materials in：Ostrich bone 30%-70%, ostrich muscle
10%-30%, ostrich blood 10%-30%, ostrich oil 0.3%-3%, dextrin 10%-30% are xylitol 20%-40%, vitamin C 1%-5%, sweet
Chrysanthemum glycosides 0.01%-0.2%, peppermint oil 0.01-1%.
2. a kind of ostrich bone sugar-free tablet according to claim 1, it is characterised in that comprise the following steps：
1）Step 1, ostrich bone is crushed, and is sieved, and makes ostrich bone meal；
2）Step 2, takes ostrich muscle and ostrich blood, smashes, put jacketed stainless cylinder of steel, add water, Jing after compound ferment treatment, hydrolysis
Liquid is filtered, and filtrate is spray-dried and makes ostrich muscle blood polypeptide powder；
3）Step 3, the preparation method of ostrich oil is：With ostrich adipose tissue as raw material, smash, be placed in extraction element, add water
Extract, ostrich crude oil is filtered to obtain in layering, separation of oil；By ostrich crude oil heating and melting, weak caustic solution is added, is stirred evenly, be layered, received
The process of oil-collecting phase dehydration, obtains ostrich oil；Or with ostrich adipose tissue as raw material, smash, it is placed in extraction element, adds water, adds
Dilute alkaline soln, stirring, layering are collected oil phase dehydration, obtain ostrich oil；
4）Step 4, by ostrich bone meal, ostrich muscle blood polypeptide powder, ostrich oil, vitamin C, peppermint oil, dextrin, xylitol, stevia rebaudianum
Glycosides mixing granulation；
5）Step 5, it is grain is compressing and pack.
3. a kind of ostrich bone sugar-free tablet according to claim 2, it is characterised in that comprise the following steps：
In the step 2, ostrich polypeptide powder preparation process is：By ostrich muscle and ostrich blood, temperature control type jacketed stainless steel reaction is put
Tank, by the compound enzyme for having activated, between 1%-10%, pH value is 6.0-8.0 to enzyme bottom ratio, and 40-60 DEG C is incubated 2 hours -6
Hour, hydrolysis, hydrolyzate are filtered, and filtrate is spray-dried and makes ostrich muscle blood polypeptide powder, and its purity range can be 60%-80%
The compound enzyme is：Plant rennet, animal protease, microbial protease, neutral proteinase or polypeptidase；
The activation method is：Compound enzyme 100mg adds 10mL-30mL1%-2% NaCI solution, 35 DEG C -45 DEG C, is incubated
- 2 hours 0.5 hour.
4. a kind of ostrich bone sugar-free tablet according to claim 2, it is characterised in that comprise the following steps：
Ostrich oil preparation process in the step 3：
Ostrich adipose tissue is taken, is smashed, put in extraction element, added 2-10 times to measure water and extract 1-2 time, each extraction time 1 is little
When -2 hours, Extracting temperature is 80 DEG C -130 DEG C, and extract is filtered, and filtrate separates oil phase and obtains ostrich in 25 DEG C of -75 DEG C of stratification
Bird oil；
Or ostrich adipose tissue is taken, and smash, put in extraction element, add 2-10 times to measure water and extract 1-2 time, each extraction time 1
Hour -2 hours, Extracting temperature are 80 DEG C -130 DEG C, and extract is filtered, and filtrate separates oil phase and adds in 25 DEG C of -75 DEG C of stratification
Hot uniform thawing, adds 1%-10% weak caustic solutions, stirring in 25 DEG C of -75 DEG C of stratification, to collect oil phase and obtain ostrich oil；
Or ostrich adipose tissue is taken, and smash, put in extraction element, add 2-10 times to measure water and extract 1-2 time, each extraction time 1
Hours -2 hours, Extracting temperature was 80 DEG C -130 DEG C, adds 1%-10% weak caustic solutions, was stirred, and was filtered, and filtrate filtrate is in 25
DEG C -75 DEG C of stratification, separate oil phase and obtain ostrich oil.
5. any ostrich bone sugar-free tablet according to claim 1 ~ 4, in anti-treating rheumatic arthritis, arteriosclerosis and obstruction of lower limbs, shoulder
Application in inflammation, osteoporosis, malignant tumour and diabetes.
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| CN1745627A (en) * | 2004-09-10 | 2006-03-15 | 丁庆 | Ostrich blood and active function of related products |
| CN101824362A (en) * | 2010-03-09 | 2010-09-08 | 浙江大学 | Method for extracting ostrich oil by petroleum ether solvent |
| CN102277228A (en) * | 2011-07-18 | 2011-12-14 | 中国科学院成都生物研究所 | Preparation method and application of refined ostrich oil |
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