CN101647559A - Bone strengthening and calcium supplementing preparation and preparation method thereof - Google Patents

Bone strengthening and calcium supplementing preparation and preparation method thereof Download PDF

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CN101647559A
CN101647559A CN200810051077A CN200810051077A CN101647559A CN 101647559 A CN101647559 A CN 101647559A CN 200810051077 A CN200810051077 A CN 200810051077A CN 200810051077 A CN200810051077 A CN 200810051077A CN 101647559 A CN101647559 A CN 101647559A
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extract
raw material
deer
liquid
soaking
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赵景辉
王再幸
潘永岐
杨福合
陈立志
徐志臣
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赵景辉
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Abstract

The invention relates to a bone strengthening and calcium supplementing preparation and a preparation method thereof. The preparation method is characterized by comprising the following steps: continuously extracting nutrient substances from cartialgenous, deer bone and deer sinew at normal temperature by adopting a high-voltage pulse electric field; and according to the following formula: 10.71 to 26.32 grams of cartialgenous, 39.47 to 53.57 grams of deer bone extract, 34.21 to 37.50 grams of deer sinew extract and 0.00001 to 0.00006 gram of vitamin D, dispensing, evenly mixing, split-charging and packing the nutrient substances to form a finished product. The preparation and the preparation method have the characteristics of unique and reasonable formula, novel technique, normal-temperature continuous extraction, high extraction rate, sterilization function in an extraction process, high bioavailability, short extraction time, low cost, advanced calcium supplementing method, and thelike.

Description

A kind of strong bone calcium-supplementing preparation and preparation method thereof
Technical field:
The present invention relates to a kind of strong bone calcium-supplementing preparation and preparation method thereof, particularly relate to a kind of strong bone calcium-supplementing preparation that contains pilose antler, deer bone, deer's sinew extraction active component and preparation method thereof.
Background technology:
Raise 6,000,000 of deer at present in the world, about 1,000,000 of China's artificial feeding is produced pilose antler per year and is reached ten thousand kilograms of 7-8, and deer bone, deer's sinew resource are abundant equally.Compendium of Material Medica record, pilose antler have production of sperm to mend marrow, the Yiyang of nourishing blood, strengthening the muscles and bones, the strong will of beneficial gas, control deafness, tinnitus, impotence, seminal emission, uterus void are cold, the uterine bleeding band down and all deficient effects.Modern study proves: pilose antler has to be regulated organism metabolism, strengthen muscle power, improves hematopoiesis function, promotes to grow, improve body immunity, promotes functions such as various physiological function activities, is one of the famousst and precious animal drugs.The deer bone is the bone of animal in deer family, and it is sweet to distinguish the flavor of, and low-grade fever is nontoxic.Contain a large amount of calcium constituents.Deer's sinew is the muscle of animal in deer family four limbs.Warm in nature, lightly seasoned little salty, nontoxic.Effect: kidney-replenishing, strengthen the bone.
Vitamin D is mainly used in composition and keeps the strong of bone.It is used to prevent and treat children's rickets and adult's rickets, arthralgia or the like.The people who suffers from osteoporosis can effectively improve the trap of calcium ion by interpolation suitable vitamins D and magnesium.
The deer bone contains abundant chondroitin, calcium activated, ossein, is the important source of calcium activated.The BIOLOGICAL CALCIUM of extracting from the deer bone is different from common chemical calcium, and it is convenient to absorb, and is without any side effects.Can not only promote that bone is stronger, also help prevention of osteoporosis and treatment.
Calcium citrate is a kind of novel calcium of organic acid, and is non-stimulated to stomach and intestine.Calcium citrate has special dissolving combination, can prevent kidney stone, and the possibility that fracture takes place is slowed down osteoporosis and osteoproliferation, is particularly suitable for pregnant woman, women breast-feeding their children, the elderly's the skeleton development of replenishing the calcium and needing and helping the growth stage juvenile
Calcium citrate is the product of comparison a new generation, activation does not absorb because calcium citrate does not need hydrochloric acid in gastric juice, absorptivity the best, can not produce the shortcoming of carbon dioxide gaseous distention again as calcium carbonate, and the solubility of citrate in blood be high than the oxalates that produces calculus, so citrate can grab the calcium in the calculus composition, many functions of preventing calculus, calcium than other is better, and medical circle comes into fashion at home.
Citric acid and calcium malate have highly dissoluble, high absorbing property of biology, reduce the advantage that iron absorbs obstruction, excellent flavor and safety non-toxic.The a large amount of clinical datas that abroad provide show, its absorptivity in human body, bioavilability and the effect that strengthens the human body bone density obviously is better than other calcium sources are classic a kind of calcium sources in the world today.
Calcium in the bone mainly exists with hydroxyapatite crystal and unformed calcium phosphate form, and solubility is low, is unfavorable for human body absorbing bone calcium.Want to promote wherein absorbing of calcium; must destroy hydroxylapatite crystal; the calcium that obtains dissociating; this technology utilizes the micro mist pulverizer with the material micronize; promote its dissolving; but add organic acid decomposes collagen fiber, the destruction hydroxyapatite combines with collagenous fibres, thereby reaches the purpose of calcium in the stripping bone.
The art of this patent serves as to extract auxiliary agent with citric acid and malic acid, under the high-pressure pulse electric effect, high-intensity electric current impels acid ion and calcium salt all to polarize, the possibility that is bonded to each other increases, and the collagen in the bone is by behind the highfield, and separation of charge causes reorientates or be out of shape, and causes covalent bond to disconnect, itself and hydroxyapatite are organically combined further destroy, make calcium combine the formation calcium citrate with citric acid or malic acid and the calcium malate chance increases greatly.
Theory of traditional Chinese medical science thinks that kidney has the effect of " main bone is given birth to marrow ", asthenia of renal qi is osteoporotic cause, therefore when the treatment osteoporosis, often uses the kidney-nourishing tcm drug that some have strong bone effect, that commonly sees has a pilose antler, has the effect of kidney-replenishing, benefiting essence-blood, strengthening the bones and muscles.Deer's sinew has kidney-replenishing, effect strengthens the bone.The deer bone contains a large amount of calcium.The strong bone pharmacological research of kidney-nourishing tcm drug shows that pilose antler can not only promote the sexual gland secretion, also contains estrogen such as estradiol, can treat osteoporosis very effectively.
Summary of the invention:
The object of the present invention is to provide a kind of strong bone calcium-supplementing preparation and preparation method thereof, adopt the high-pressure pulse electric extractive technique to extract pilose antler, deer bone, deer's sinew active component, owing to be that normal temperature extracts, kept pilose antler ecosystem state to greatest extent, it has prescription uniqueness, reasonable, has made full use of deer byproduct resource; Normal-temperature continuous is extracted, technology advanced person; Extraction time is short, cost is low; Technology novelty, recovery rate height, leaching process has bactericidal action; The method of replenishing the calcium advanced person.
Technical scheme of the present invention is achieved in that a kind of strong bone calcium-supplementing preparation and preparation method thereof, it is characterized in that: composition of raw materials consists of by following weight
Deer antler extract: 10.71~26.32
Os Cervi extract: 39.47~53.57
Deer sinew extract: 34.21~37.50
Vitamin D: 0.00001~0.00006
Concrete processing step is
At first pilose antler is extracted, technology is as follows:
(1) do not select the pilose antler damaging by worms, pollute as raw material;
(2) be that alcolhol burner or electric furnace burn the pilose antler fine hair with no pyrotechnics, then branch decomposed;
(3) the pilose antler crosscut is become the fine and soft sheet of 2-4mm with the pilose antler slicer;
(4) the fine and soft sheet after will cutting with the Baily pulverizer is crushed to more than 60 orders;
(5) weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking;
(6) with raw material and after extracting the stirring solvent mixing, stirring and evenly mixing is static again to place 0.5h;
(7) raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20-30kv, umber of pulse 4-8 is a parameter extraction, collects extract continuously;
(8) extract being pumped into flame filter press filters;
(9) filtered fluid is carried out vacuum and be concentrated into liquid extract;
(10) drying: become powder standby liquid extract spray-drying or freeze drying;
The deer bone is extracted, and technology is as follows:
A kind of extraction auxiliary agent, its formulation weight ratio is:
Citric acid: malic acid=0.8-1.2: 0.9-1.3
Concrete processing step is as follows:
(1) selects and do not have mouldy, the deer bone that pollutes as raw material;
(2) reject residual meat, marrow, clean;
(3) crosscut of deer bone is become the osteocomma of 2-4mm with slicer;
(4) osteocomma or meal are put into 121 ℃ in autoclaving pot, 0.1MPa steams 1h;
(5) below raw material pulverizing to 60 order after usefulness Baily pulverizer will steam;
(6) weigh afterwards by material: acid: liquid=1: 1: 9 adding mixed acid, extraction solvent and raw material soaking, static 24h;
(7) raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 4 is a parameter extraction, collects extract simultaneously;
(8) with raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again;
(9) raw material after will soaking with the liquid pump again is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20-30kv, umber of pulse 4-8 is a parameter extraction, collects extract continuously;
(10) filter: extract is pumped into flame filter press filter;
(11) filtered fluid is carried out vacuum and be concentrated into liquid extract;
(12) become powder standby liquid extract spray-drying or freeze drying;
Deer's sinew extracts, and technology is as follows:
(1) do not select the deer's sinew damaging by worms, pollute as raw material;
(2) remove the hoof first;
(3) deer's sinew is crushed to about 60 orders;
(4) weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking;
(5) with raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again;
(6) raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20-30kv, umber of pulse 4-8 is a parameter extraction, collects extract continuously;
(7) extract being pumped into flame filter press filters;
(8) filtered fluid is carried out vacuum and be concentrated into liquid extract;
(9) become powder standby liquid extract spray-drying or freeze drying;
Pilose antler, deer bone, deer sinew extract and vitamin D are prepared burden → mixed → packing → packing → product by prescription
Good effect of the present invention is successful high-voltage pulse electric field being applied in the extraction of deer product active ingredient, for similar research is offered reference; Realized that normal temperature extracts and the sterilization one, the assurance heat-sensitive substance is not degraded; Continuously, rapid extraction, energy-saving and environmental protection, efficient.4. bioavilability height; High in technological content.5. extraction time is short, cost is low; Prescription uniqueness, reasonable, the method for replenishing the calcium advanced person.
The specific embodiment:
The present invention will be further described below in conjunction with embodiment:
Embodiment 1:
Pilose antler is extracted, and technology is as follows: do not select the pilose antler damaging by worms, pollute as raw material; With no pyrotechnics is that alcolhol burner or electric furnace burn the pilose antler fine hair, then branch is decomposed; The pilose antler crosscut is become the fine and soft sheet of 2-4mm with the pilose antler slicer; Fine and soft sheet after will cutting with the Baily pulverizer is crushed to more than 60 orders; Weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking; With raw material and after extracting the stirring solvent mixing, stirring and evenly mixing is static again to place 0.5h; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20kv, umber of pulse 4 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Dry: as to become powder standby liquid extract spray-drying or freeze drying;
The deer bone is extracted, and technology is as follows:
A kind of extraction auxiliary agent, its formulation weight ratio is:
Citric acid: malic acid=1.0: 1.0
Concrete processing step is as follows: selecting does not have mouldy, the deer bone that pollutes as raw material; Reject residual meat, marrow, clean; The crosscut of deer bone is become the osteocomma of 2-4mm with slicer; Osteocomma or meal are put into 121 ℃ in autoclaving pot, and 0.1MPa steams 1h; Below raw material pulverizing to 60 order after will steaming with the Baily pulverizer; It is back by material to weigh: acid: liquid=1: 1: 9 adding mixed acid, extraction solvent and raw material soaking, static 24h; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 4 is a parameter extraction, collects extract simultaneously; With raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again; Raw material after will soaking with the liquid pump again is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20kv, umber of pulse 4 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Become powder standby liquid extract spray-drying or freeze drying;
Deer's sinew extracts, and technology is as follows: do not select the deer's sinew damaging by worms, pollute as raw material; Remove the hoof first; Deer's sinew is crushed to about 60 orders; Weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking; With raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20kv, umber of pulse 4 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Become powder standby liquid extract spray-drying or freeze drying;
Deer antler extract 12.50g, Os Cervi extract 50.00g, deer sinew extract 37.50g and vitamin D 0.00006g are mixed the back packing and be packaged as product.
Embodiment 2:
Pilose antler is extracted, and technology is as follows: do not select the pilose antler damaging by worms, pollute as raw material; With no pyrotechnics is that alcolhol burner or electric furnace burn the pilose antler fine hair, then branch is decomposed; The pilose antler crosscut is become the fine and soft sheet of 2-4mm with the pilose antler slicer; Fine and soft sheet after will cutting with the Baily pulverizer is crushed to more than 60 orders; Weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking; With raw material and after extracting the stirring solvent mixing, stirring and evenly mixing is static again to place 0.5h; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 25kv, umber of pulse 6 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Dry: as to become powder standby liquid extract spray-drying or freeze drying;
The deer bone is extracted, and technology is as follows:
A kind of extraction auxiliary agent, its formulation weight ratio is:
Citric acid: malic acid=1.2: 1.3
Concrete processing step is as follows: selecting does not have mouldy, the deer bone that pollutes as raw material; Reject residual meat, marrow, clean; The crosscut of deer bone is become the osteocomma of 2-4mm with slicer; Osteocomma or meal are put into 121 ℃ in autoclaving pot, and 0.1MPa steams 1h; Below raw material pulverizing to 60 order after will steaming with the Baily pulverizer; It is back by material to weigh: acid: liquid=1: 1: 9 adding mixed acid, extraction solvent and raw material soaking, static 24h; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 4 is a parameter extraction, collects extract simultaneously; With raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again; Raw material after will soaking with the liquid pump again is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 25kv, umber of pulse 6 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Become powder standby liquid extract spray-drying or freeze drying;
Deer's sinew extracts, and technology is as follows: do not select the deer's sinew damaging by worms, pollute as raw material; Remove the hoof first; Deer's sinew is crushed to about 60 orders; Weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking; With raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 25kv, umber of pulse 6 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Become powder standby liquid extract spray-drying or freeze drying;
Deer antler extract pilose antler: 10.71g, Os Cervi extract 53.57g, deer sinew extract 35.71g and vitamin D 0.00002g are mixed the back packing and be packaged as product.
Embodiment 3:
Pilose antler is extracted, and technology is as follows: do not select the pilose antler damaging by worms, pollute as raw material; With no pyrotechnics is that alcolhol burner or electric furnace burn the pilose antler fine hair, then branch is decomposed; The pilose antler crosscut is become the fine and soft sheet of 2-4mm with the pilose antler slicer; Fine and soft sheet after will cutting with the Baily pulverizer is crushed to more than 60 orders; Weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking; With raw material and after extracting the stirring solvent mixing, stirring and evenly mixing is static again to place 0.5h; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 8 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Dry: as to become powder standby liquid extract spray-drying or freeze drying;
The deer bone is extracted, and technology is as follows:
A kind of extraction auxiliary agent, its formulation weight ratio is:
Citric acid: malic acid=0.8: 0.9
Concrete processing step is as follows: selecting does not have mouldy, the deer bone that pollutes as raw material; Reject residual meat, marrow, clean; The crosscut of deer bone is become the osteocomma of 2-4mm with slicer; Osteocomma or meal are put into 121 ℃ in autoclaving pot, and 0.1MPa steams 1h; Below raw material pulverizing to 60 order after will steaming with the Baily pulverizer; It is back by material to weigh: acid: liquid=1: 1: 9 adding mixed acid, extraction solvent and raw material soaking, static 24h; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 4 is a parameter extraction, collects extract simultaneously; With raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again; Raw material after will soaking with the liquid pump again is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 8 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Become powder standby liquid extract spray-drying or freeze drying;
Deer's sinew extracts, and technology is as follows: do not select the deer's sinew damaging by worms, pollute as raw material; Remove the hoof first; Deer's sinew is crushed to about 60 orders; Weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking; With raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again; Raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 8 is a parameter extraction, collects extract continuously; Extract is pumped into flame filter press to be filtered; Filtered fluid is carried out vacuum be concentrated into liquid extract; Become powder standby liquid extract spray-drying or freeze drying;
Deer antler extract 26.32g, Os Cervi extract 39.47g, deer sinew extract 35.21g and vitamin D 0.00004g are mixed the back packing and be packaged as product.

Claims (2)

1, a kind of strong bone calcium-supplementing preparation, it is characterized in that: composition of raw materials consists of by following weight
Deer antler extract: 10.71~26.32
Os Cervi extract: 39.47~53.57
Deer sinew extract: 34.21~37.50
Vitamin D: 0.00001~0.00006
2, the preparation method of a kind of strong bone calcium-supplementing preparation according to claim 1 is characterized in that its concrete processing step is:
At first pilose antler is extracted, technology is as follows:
(1) do not select the pilose antler damaging by worms, pollute as raw material;
(2) be that alcolhol burner or electric furnace burn the pilose antler fine hair with no pyrotechnics, then branch decomposed;
(3) the pilose antler crosscut is become the fine and soft sheet of 2-4mm with the pilose antler slicer;
(4) the fine and soft sheet after will cutting with the Baily pulverizer is crushed to more than 60 orders;
(5) weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking;
(6) with raw material and after extracting the stirring solvent mixing, stirring and evenly mixing is static again to place 0.5h;
(7) raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20-30kv, umber of pulse 4-8 is a parameter extraction, collects extract continuously;
(8) extract being pumped into flame filter press filters;
(9) filtered fluid is carried out vacuum and be concentrated into liquid extract;
(10) drying: become powder standby liquid extract spray-drying or freeze drying;
The deer bone is extracted, and technology is as follows:
A kind of extraction auxiliary agent, its formulation weight ratio is:
Citric acid: malic acid=0.8-1.2: 0.9-1.3
Concrete processing step is as follows:
(1) selects and do not have mouldy, the deer bone that pollutes as raw material;
(2) reject residual meat, marrow, clean;
(3) crosscut of deer bone is become the osteocomma of 2-4mm with slicer;
(4) osteocomma or meal are put into 121 ℃ in autoclaving pot, 0.1MPa steams 1h;
(5) below raw material pulverizing to 60 order after usefulness Baily pulverizer will steam;
(6) weigh afterwards by material: acid: liquid=1: 1: 9 adding mixed acid, extraction solvent and raw material soaking, static 24h;
(7) raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 30kv, umber of pulse 4 is a parameter extraction, collects extract simultaneously;
(8) with raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again;
(9) raw material after will soaking with the liquid pump again is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20-30kv, umber of pulse 4-8 is a parameter extraction, collects extract continuously;
(10) filter: extract is pumped into flame filter press filter;
(11) filtered fluid is carried out vacuum and be concentrated into liquid extract;
(12) become powder standby liquid extract spray-drying or freeze drying;
Deer's sinew extracts, and technology is as follows:
(1) do not select the deer's sinew damaging by worms, pollute as raw material;
(2) remove the hoof first;
(3) deer's sinew is crushed to about 60 orders;
(4) weigh the back by material: liquid=1: 10 adds raw material and 40-70% alcohol extract solvent soaking;
(5) with raw material and after extracting the stirring solvent mixing, place 0.5h stirring and evenly mixing again;
(6) raw material after will soaking with the liquid pump is continuously pumped into high voltage pulse and extracts in the unit, and with field intensity 20-30kv, umber of pulse 4-8 is a parameter extraction, collects extract continuously;
(7) extract being pumped into flame filter press filters;
(8) filtered fluid is carried out vacuum and be concentrated into liquid extract;
(9) become powder standby liquid extract spray-drying or freeze drying;
Pilose antler, deer bone, deer sinew extract and vitamin D are prepared burden → mixed → packing → packing → product by prescription.
CN200810051077A 2008-08-15 2008-08-15 Bone strengthening and calcium supplementing preparation and preparation method thereof Pending CN101647559A (en)

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Application Number Priority Date Filing Date Title
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CN101647559A true CN101647559A (en) 2010-02-17

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102626463A (en) * 2012-05-07 2012-08-08 赵全成 Natural medicine compound for increasing bone mineral density and preventing and treating osteoporosis
CN102845659A (en) * 2011-07-01 2013-01-02 湖南晟通科技集团有限公司 Velvet jelly and its preparation method
CN103623002A (en) * 2013-11-24 2014-03-12 郭国康 Health-care joint composition
CN106417850A (en) * 2016-12-15 2017-02-22 通化万发生态科技有限公司 Cervine sinew-bovine ossein tabletted candy
CN111297904A (en) * 2020-04-10 2020-06-19 中国农业科学院特产研究所 New application of cornu Cervi Pantotrichum aqueous extract

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102845659A (en) * 2011-07-01 2013-01-02 湖南晟通科技集团有限公司 Velvet jelly and its preparation method
CN102845659B (en) * 2011-07-01 2016-03-23 湖南晟通科技集团有限公司 A kind of pilose antler jelly and preparation method thereof
CN102626463A (en) * 2012-05-07 2012-08-08 赵全成 Natural medicine compound for increasing bone mineral density and preventing and treating osteoporosis
CN103623002A (en) * 2013-11-24 2014-03-12 郭国康 Health-care joint composition
CN103623002B (en) * 2013-11-24 2016-04-27 郭国康 A kind of health-care joint composition
CN106417850A (en) * 2016-12-15 2017-02-22 通化万发生态科技有限公司 Cervine sinew-bovine ossein tabletted candy
CN111297904A (en) * 2020-04-10 2020-06-19 中国农业科学院特产研究所 New application of cornu Cervi Pantotrichum aqueous extract

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Application publication date: 20100217