CN106492152A - A kind of skin surface disinfecting anti inflammatory agent and preparation method thereof - Google Patents

A kind of skin surface disinfecting anti inflammatory agent and preparation method thereof Download PDF

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CN106492152A
CN106492152A CN201610943530.9A CN201610943530A CN106492152A CN 106492152 A CN106492152 A CN 106492152A CN 201610943530 A CN201610943530 A CN 201610943530A CN 106492152 A CN106492152 A CN 106492152A
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oil
eugenol
citral
rhizoma zingiberis
zingiberis recens
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陈厚兵
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/11Aldehydes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A kind of skin surface disinfecting anti inflammatory agent and preparation method thereof, it is characterised in that:According to the mass fraction, by 0.8%~1.5% citral, 1.2%~3% eugenol, 0.5%~1.2% oil of Rhizoma Zingiberis Recens, remaining is that edible ethanol is obtained as raw material, the present invention adopts citral, eugenol, oil of Rhizoma Zingiberis Recens and edible ethanol are made up of raw material, citral, eugenol, oil of Rhizoma Zingiberis Recens and for edible ethanol mixing after, pharmacologically mutually promoting, joint plays pharmacological action, reducing swelling and alleviating pain especially to skin, disinfecting anti inflammatory, bacterio static itching-relieving, avoid infection, prevent the aspect effect is significant such as tetanus, antiinflammatory sterilization can not only be carried out to skin surface, and can also fundamentally carry out anti-inflammation and sterilization, promote subcutaneous tissue blood circulation, blood circulation promoting and blood stasis dispelling, body immunity can be improved.

Description

A kind of skin surface disinfecting anti inflammatory agent and preparation method thereof
Technical field
The present invention relates to a kind of disinfecting anti inflammatory agent, more particularly to a kind of skin surface disinfecting anti inflammatory agent and preparation method thereof, Belong to antiinflammatory disinfection drug technical field.
Background technology
At present, the disinfecting anti inflammatory of skin surface is typically necessary and uses disinfectant, and existing disinfectant is mostly containing having The chemosynthesis medicament of certain toxic and side effects, if the less words of chemosynthesis chemical content, the antiinflammation to skin surface Not good, work slow, it is impossible to reach preferable anti-inflammatory effects;If chemosynthesis chemical content is more, chemosynthesis medicament Certain toxic and side effects can be produced to human body, be unfavorable for that health, life-time service can also produce certain Drug resistance.In addition, The effect on driving birds is not good of chemosynthesis disinfectant, can only be carried out disinfection to skin surface mostly, it is impossible to fundamentally carry out antiinflammatory, especially It is for hemorrhoid, blister, oral ulcer etc..
Such as Chinese patent mandate Publication No.:CN 104888204A, the day for announcing is:The patent of invention on the 9th of September in 2015 A kind of compound skin mucosa disinfectant and preparation method thereof is disclosed, the raw material composition and its parts by weight of the disinfectant is made For:Ocean probiotic bacteria DNA unwinding enzyme 3-5 parts, polyhexamethylene guanidine 5-10 parts, microalgae polysaccharide 2-6 parts, marine organisms compound enzyme 13 parts of 5-8 parts, deionized water 58-72 parts and plant extraction liquid;13 parts of the plant extraction liquid is:By 6 parts of Herba Violae, Radix Dichroae 3 parts, 3 parts of Herba Eupatorii, 1 part of Rhizoma Atractylodis make powder, mixed-powder is obtained leachate through percolation;By leachate successively through stand, Filter, purify, obtain plant extraction liquid.But the disinfectant can only carry out antiinflammatory sterilization to skin surface, it is impossible to fundamentally Carry out antiinflammatory.
Content of the invention
The purpose of the present invention is the effect on driving birds is not good for existing chemosynthesis disinfectant, with certain toxic and side effects, greatly How skin surface can only be carried out disinfection, it is impossible to fundamentally carry out the defect and deficiency of antiinflammatory, a kind of disinfecting anti inflammatory is now provided Effect is good, and skin surface can not only be carried out disinfection, and fundamentally can also carry out anti-inflammation and sterilization, without toxic and side effects A kind of skin surface disinfecting anti inflammatory agent and preparation method thereof.
For realizing the purpose of the present invention, the technical solution of the present invention is:A kind of skin surface antiinflammatory disinfectant, its are special Levy and be:According to the mass fraction, by 0.8%~1.5% citral, 1.2%~3% eugenol, 0.5%~1.2% oil of Rhizoma Zingiberis Recens, Remaining is that edible ethanol is obtained as raw material.
According to the mass fraction, by 1.2% citral, 2% eugenol, 0.8% oil of Rhizoma Zingiberis Recens, remaining be edible ethanol make It is obtained for raw material.
The alcohol content of the edible ethanol is 75%.
A kind of skin surface disinfecting anti inflammatory cream, it is characterised in that:According to the mass fraction, by 0.08%~0.15% Fructus Citri Limoniae Aldehyde, 0.12%~0.3% eugenol, 0.05%~0.12% oil of Rhizoma Zingiberis Recens, remaining be mastic as raw material be obtained.
According to the mass fraction, by 0.12% citral, 0.2% eugenol, 0.09% oil of Rhizoma Zingiberis Recens, remaining be mastic make It is obtained for raw material.
The present invention manufacture method be:A kind of skin surface antiinflammatory disinfectant preparation method, it is characterised in that including following Step:Comprise the following steps:Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to Rhizoma Zingiberis Recenss again Oil is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, disinfecting anti inflammatory is made Agent.
A kind of skin surface disinfecting anti inflammatory ointment preparation, it is characterised in that comprise the following steps:By citral and Flos Caryophylli Phenol is sufficiently mixed, and obtains mixed liquor I;Mixed liquor I is added to oil of Rhizoma Zingiberis Recens again to be sufficiently mixed, mixed liquor II is obtained;Finally will be mixed Close liquid II and be added to mix homogeneously in mastic, make disinfecting anti inflammatory cream.
The invention has the beneficial effects as follows:
1st, the present invention adopts citral, eugenol, oil of Rhizoma Zingiberis Recens and edible ethanol to be made up of raw material, citral, eugenol, life Oil of ginger and for edible ethanol mixing after, pharmacologically mutually promoting, joint plays pharmacological action, and especially the detumescence of skin is stopped Bitterly, anti-inflammation and sterilization, avoid infection, prevent the aspect effect is significant such as tetanus.
2nd, the present invention draws materials extensively, easy to process, and product stability is good, does not contain chemosynthesis medicament composition, does not have poison Side effect, can not only carry out disinfection antiinflammatory to skin surface, and can also fundamentally carry out anti-inflammation and sterilization, promote subcutaneous group Knit blood circulation, blood circulation promoting and blood stasis dispelling, it is possible to increase body immunity.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is described in further detail.
A kind of skin surface disinfecting anti inflammatory agent according to the present invention, it is characterised in that:According to the mass fraction, by 0.8%~ 1.5% citral, 1.2%~3% eugenol, 0.5%~1.2% oil of Rhizoma Zingiberis Recens, remaining be edible ethanol as raw material be obtained.
According to the mass fraction, by 1.2% citral, 2% eugenol, 0.8% oil of Rhizoma Zingiberis Recens, remaining be edible ethanol make It is obtained for raw material.
The alcohol content of the edible ethanol is 75%.
A kind of skin surface disinfecting anti inflammatory cream, it is characterised in that:According to the mass fraction, by 0.08%~0.15% Fructus Citri Limoniae Aldehyde, 0.12%~0.3% eugenol, 0.05%~0.12% oil of Rhizoma Zingiberis Recens, remaining be mastic as raw material be obtained.
According to the mass fraction, by 0.12% citral, 0.2% eugenol, 0.09% oil of Rhizoma Zingiberis Recens, remaining be mastic make It is obtained for raw material.
A kind of skin surface disinfecting anti inflammatory agent preparation method, it is characterised in that comprise the following steps:
Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to oil of Rhizoma Zingiberis Recens again to be sufficiently mixed, is obtained Mixed liquor II;Mixed liquor II is added to mix homogeneously in the edible ethanol that ethanol is content 75% finally, disinfecting anti inflammatory is made Agent.
A kind of skin surface antiinflammatory sterilization ointment preparation, it is characterised in that comprise the following steps:
Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to oil of Rhizoma Zingiberis Recens again to be sufficiently mixed, is obtained Mixed liquor II;Mixed liquor II is added to mix homogeneously in mastic finally, disinfecting anti inflammatory cream is made.
Antiinflammatory disinfectant of the present invention adopts citral, eugenol, oil of Rhizoma Zingiberis Recens and is made up of edible ethanol raw material, according to matter Measuring percentages is respectively:Citral 0.8%~1.5%, eugenol 1.2%~3%, oil of Rhizoma Zingiberis Recens 0.5%~1.2%, remaining is edible Ethanol, and be mixed.Eugenol can also be replaced using Oleum Ocimi Gratissimi.Existing disinfectant is mostly certain malicious containing having The chemosynthesis medicament of side effect, if the less words of chemosynthesis chemical content, acts on not to the disinfecting anti inflammatory of skin surface Good, work slow, it is impossible to reach preferable anti-inflammation and sterilization effect;If chemosynthesis chemical content is more, chemical synthetic drug Agent can produce certain toxic and side effects to human body, be unfavorable for health, can also produce certain Drug resistance when long-term.
And chemosynthesis medicament composition in technical scheme, is not contained, citral, eugenol and oil of Rhizoma Zingiberis Recens are divided equally Do not extract from plant and separate, skin will not be caused to corrode and be injured, also any toxic and side effects will not be produced to human body. Citral, eugenol, oil of Rhizoma Zingiberis Recens with mix for edible ethanol after, pharmacologically mutually promoting, joint plays pharmacological action, especially To the reducing swelling and alleviating pain of skin, anti-inflammation and sterilization, the aspect effect is significant such as avoid infection, unexpected disinfecting anti inflammatory effect is generated Really.
Citral, is colourless or slightly yellow liquid, in strong citrus scented, dissolves in the organic solvents such as ethanol, Ke Yicong Refine in Fructus Citri Limoniae oil, white lemon oil, citrus oils, litsea cubeba oil, Herba Verbenae oil isolated.There is preferable antibacterial action, example Such as anti-aspergillosiss.
Eugenol, be slightly yellow have strong cloves fragrance, be practically insoluble in water to yellow liquid, can with ethanol, chlorine, Ether and oil are miscible, and natural eugenol can dry flower from Flos Caryophylli mainly with the myrtle rich in Oleum Caryophylli Flower bud is obtained through distillation.Eugenol has inhibitory action to pathogenic funguses, to staphylococcus aureuses and pneumonia, dysentery, large intestine, change The bacillus such as shape, tuberculosis have inhibitory action.
Oil of Rhizoma Zingiberis Recens, from fresh ginger can extract oil of Rhizoma Zingiberis Recens by the way of distillation, draw materials extensively, and cost is relatively low, oil of Rhizoma Zingiberis Recens Containing multiple components, such as zingiberene, zingiberol, zingiberone etc..Oil of Rhizoma Zingiberis Recens can stimulate teleneuron, promote subcutaneous tissue blood circulation, In addition also there is preferable antibacterial and protozoacide ability.
Citral of the present invention and eugenol are sufficiently mixed, and oil of Rhizoma Zingiberis Recens coordinates citral and eugenol to use, and oil of Rhizoma Zingiberis Recens can Stimulate teleneuron, with well infiltration guiding function so that citral and eugenol can fast direct up in subcutaneous tissue Portion, promotes subcutaneous tissue blood circulation, blood circulation promoting and blood stasis dispelling, it is possible to increase body immunity.Subcutaneous tissue blood circulation is promoted to accelerate Afterwards, blister, moving tissue liquid diffusion can be made, is acted on good reducing swelling and alleviating pain, mixed citral has very to funguses Good inhibitory action, eugenol have good bactericidal action to antibacterial, and oil of Rhizoma Zingiberis Recens has suppression well and kills to virus to be made With.In addition citral and eugenol have sterilization, antibacterial action well, can reach good anti-inflammatory effects, instant effect.
The present invention can make liquid preparation, can also make solid-state unguentum, by citral, Flos Caryophylli when making solid-state unguentum The content of phenol and oil of Rhizoma Zingiberis Recens reduces, and is blended in mastic and makes, and mastic is lotion of toothpaste or vaseline.If treatment oral cavity is burst Infectionss can only use liquid preparation, can be inconvenient using solid-state unguentum.The present invention to hemorrhoid, oral ulcer, traumatic injury of skin, cold injury, Burn etc. is with good disinfecting anti inflammatory, reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling, the effect for preventing infection.A kind of skin surface disappears The specific embodiment of scorching agent is as follows:
Embodiment 1:According to the mass fraction, adopt 0.8% citral, 1.2% eugenol, 0.5% oil of Rhizoma Zingiberis Recens, remaining for food It is obtained as raw material with ethanol.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to Rhizoma Zingiberis Recenss again Oil is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory sterilization is made Agent.
Embodiment 2:According to the mass fraction, adopt 1% citral, 1.4% eugenol, 0.6% oil of Rhizoma Zingiberis Recens, remaining for Edible ethanol is obtained as raw material.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory sterilization is made Agent.
Embodiment 3:According to the mass fraction, using 1.1% citral, 1.6% eugenol, 0.7% oil of Rhizoma Zingiberis Recens, remaining It is obtained as raw material for edible ethanol.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Again mixed liquor I is added to Oil of Rhizoma Zingiberis Recens is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory is made and is disappeared Toxic agent.
Embodiment 4:According to the mass fraction, adopt 1.2% citral, 2% eugenol, 0.8% oil of Rhizoma Zingiberis Recens, remaining for Edible ethanol is obtained as raw material.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory sterilization is made Agent.
Embodiment 5:According to the mass fraction, adopt 1.4% citral, 2.5% eugenol, 1% oil of Rhizoma Zingiberis Recens, remaining for Edible ethanol is obtained as raw material.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory sterilization is made Agent.
Embodiment 6:According to the mass fraction, adopt 1.5% citral, 3% eugenol, 1.2% oil of Rhizoma Zingiberis Recens, remaining for Edible ethanol is obtained as raw material.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory sterilization is made Agent.
A kind of specific embodiment of skin surface disinfecting anti inflammatory cream is as follows:
Embodiment 1:According to the mass fraction, adopt 0.08% citral, 0.12% eugenol, 0.05% oil of Rhizoma Zingiberis Recens, remaining for Mastic is obtained as raw material.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to oil of Rhizoma Zingiberis Recens again It is sufficiently mixed, obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in mastic finally, antiinflammatory disinfecting paste is made.
Embodiment 2:According to the mass fraction, using 0.1% citral, 0.14% eugenol, 0.06% oil of Rhizoma Zingiberis Recens, its Remaining for mastic as raw material be obtained.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in mastic finally, antiinflammatory disinfecting paste is made.
Embodiment 3:According to the mass fraction, using 0.12% citral, 0.2% eugenol, 0.09% oil of Rhizoma Zingiberis Recens, its Remaining for mastic as raw material be obtained.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in mastic finally, antiinflammatory disinfecting paste is made.
Embodiment 4:According to the mass fraction, using 0.14% citral, 0.25% eugenol, 0.1% oil of Rhizoma Zingiberis Recens, its Remaining for mastic as raw material be obtained.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to life again Oil of ginger is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in mastic finally, antiinflammatory disinfecting paste is made.
Embodiment 5:According to the mass fraction, using 0.3% citral, 0.5% eugenol, 0.2% oil of Rhizoma Zingiberis Recens, remaining It is obtained as raw material for mastic.Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to Rhizoma Zingiberis Recenss again Oil is sufficiently mixed, and obtains mixed liquor II;Mixed liquor II is added to mix homogeneously in mastic finally, antiinflammatory disinfecting paste is made.
Case using skin surface antiinflammatory disinfectant of the present invention is as follows:
1st, the cause of disease:Oral ulcer, patient's name:Hou Xingjun, sex:Man, age:34 years old.Oral ulcer area is larger, with pain Bitterly, continue not disappearing for three days, take food impacted.Oral cavity ulcer spot is sprayed using the present invention, after 2 minutes, pain mitigates, Feeding process does not stimulate and pain.After 2 days, oral ulcer area reduces half to timing spray, almost painless, subsequently Oral ulcer is fully recovered.
2nd, the cause of disease:Oral ulcer, patient's name:Zhang Cai, sex:Man, age:46 years old.Oral ulcer area is larger, with Pain, continues not disappearing for two days, takes food impacted.Oral cavity ulcer spot is sprayed using the present invention, after 3 minutes, pain subtracts Gently, feeding process does not stimulate and pain.After 2 days, oral ulcer disappears timing spray substantially, almost painless, subsequently Oral ulcer is fully recovered.
3rd, the cause of disease:External hemorrhoid, patient's name:Shen Wei, sex:Man, age:42 years old.Because of fatigue, anus enclosed mass are with pain two My god, and gradually increase.External hemorrhoid position is sprayed using the present invention, relieved the pain after medication immediately antipruritic, continuous timing spray 4 days, hemorrhoid Core is started zooming out;Continuous timing spray blood stasis disappearance after 8 days, clinical symptom disappearance can be competent at daily physical work.
4th, the cause of disease:External hemorrhoid, patient's name:Fu Litao, sex:Man, age:56 years old.Because of fatigue, anus enclosed mass are with pain Three days, and gradually increase.External hemorrhoid position is sprayed using the present invention, relieved the pain after medication immediately antipruritic, continuous timing spray 3 days, Blood stasis are started zooming out;Continuous timing spray blood stasis disappearance after 9 days, clinical symptom disappearance can be competent at daily physical work.
5th, the cause of disease:Mosquito bite, patient's name:He Wen, sex:Female, age:8 years old.Play in thick grass out of doors, arm, Leg is very itched after mosquito bite incomparable, plays bag, relieves the pain antipruritic after the medicament for wiping the present invention, rises and unwrap the beginning and disappear after half an hour Move back.
6th, the cause of disease:Bacterium infection, patient's name:Wan Chen, sex:Man, age:18 years old.After participating in outdoor activities, leg is wiped Wound, and there are infection symptoms, there is redness, with pain, infection site is sprayed using medicament of the present invention, red after one hour Swollen scope is gradually reduced, and pain disappears, and interval was reused after three hours, red and swollen disappearance, recovers normal.
7th, the cause of disease:Arm wound, patient's name:Wang Jun, sex:Man, age:48 years old.Arm is caused to create in decoration construction Wound, pain are strong, wound site are sprayed using medicament of the present invention immediately, and pain disappears, and effectively prevents tetanus, promote Wound healing is entered.
8th, the cause of disease:Cold injury, patient's name:Cheng Ling, sex:Female, age:26 years old.Winter handss and Pig's feets in aspic wound, red and swollen, with Mild pain, is sprayed to wound site using medicament of the present invention, is subsided a swelling after one day, painless, after continuous timing sprays 5 days, Cold injury is cured substantially.
Medicament of the present invention is entrusted third party's specialty testing agency to carry out Candida albicans and quantitatively kills test, experimental strain For Candida albicans, culture algebraically was the 6th generation, and using electric heating constant-temperature water-bath tank, bactericidal assay is in 20 degrees Celsius of constant temperature Under carry out, the disinfectant for being adopted be the present invention medicament, act on two minutes, experiment is repeated twice, and experimental result is indicated, this Bright medicament is fine to the killing effect of Candida albicans, is 99.99% to the average eradicative rate of Candida albicans.
For escherichia coli, using pharmacy effect of the present invention 10 minutes, it is 100% to colibacillary killing rate.

Claims (7)

1. a kind of skin surface disinfecting anti inflammatory agent, it is characterised in that:According to the mass fraction, by 0.8%~1.5% citral, 1.2%~3% eugenol, 0.5%~1.2% oil of Rhizoma Zingiberis Recens, remaining be edible ethanol as raw material be obtained.
2. a kind of skin surface disinfecting anti inflammatory agent according to claim 1, it is characterised in that:According to the mass fraction, by 1.2% citral, 2% eugenol, 0.8% oil of Rhizoma Zingiberis Recens, remaining be edible ethanol as raw material be obtained.
3. a kind of skin surface disinfecting anti inflammatory agent according to claim 1, it is characterised in that:The ethanol of the edible ethanol Content is 75%.
4. a kind of skin surface disinfecting anti inflammatory cream, it is characterised in that:According to the mass fraction, by 0.08%~0.15% citral, 0.12%~0.3% eugenol, 0.05%~0.12% oil of Rhizoma Zingiberis Recens, remaining be mastic as raw material be obtained.
5. a kind of skin surface disinfecting anti inflammatory cream according to claim 1, it is characterised in that:According to the mass fraction, by 0.12% citral, 0.2% eugenol, 0.09% oil of Rhizoma Zingiberis Recens, remaining be mastic as raw material be obtained.
6. a kind of skin surface disinfecting anti inflammatory agent preparation method described in claim 1 or 2, it is characterised in that:Comprise the following steps: Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to oil of Rhizoma Zingiberis Recens again to be sufficiently mixed, is mixed Liquid II;Mixed liquor II is added to mix homogeneously in edible ethanol finally, antiinflammatory disinfectant is made.
7. a kind of skin surface disinfecting anti inflammatory ointment preparation described in claim 4 or 5, it is characterised in that:Comprise the following steps: Citral and eugenol are sufficiently mixed, mixed liquor I is obtained;Mixed liquor I is added to oil of Rhizoma Zingiberis Recens again to be sufficiently mixed, is mixed Liquid II;Mixed liquor II is added to mix homogeneously in mastic finally, disinfecting anti inflammatory cream is made.
CN201610943530.9A 2016-11-02 2016-11-02 A kind of skin surface disinfecting anti inflammatory agent and preparation method thereof Pending CN106492152A (en)

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CN107998347A (en) * 2017-11-20 2018-05-08 广州市澳万生物科技有限公司 A kind of promise Buddhist nun's skin care disinfectant based on CRHD and preparation method thereof

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