CN109248255A - Propolis drops canker sore is dedicated - Google Patents
Propolis drops canker sore is dedicated Download PDFInfo
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- CN109248255A CN109248255A CN201710569843.7A CN201710569843A CN109248255A CN 109248255 A CN109248255 A CN 109248255A CN 201710569843 A CN201710569843 A CN 201710569843A CN 109248255 A CN109248255 A CN 109248255A
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- canker sore
- propolis
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- sore
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- 208000020670 canker sore Diseases 0.000 title claims abstract description 42
- 241000241413 Propolis Species 0.000 title claims abstract description 28
- 229940069949 propolis Drugs 0.000 title claims abstract description 28
- 241001116389 Aloe Species 0.000 claims abstract description 16
- 244000223014 Syzygium aromaticum Species 0.000 claims abstract description 16
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims abstract description 16
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 16
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 15
- 241000605372 Fritillaria Species 0.000 claims abstract description 14
- 239000009636 Huang Qi Substances 0.000 claims abstract description 14
- 241000196324 Embryophyta Species 0.000 claims abstract description 13
- 239000010231 banlangen Substances 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 5
- 230000008569 process Effects 0.000 claims abstract description 4
- 239000000419 plant extract Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000008213 purified water Substances 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 claims description 2
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- 201000010099 disease Diseases 0.000 abstract description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 10
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- Health & Medical Sciences (AREA)
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- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of propolis drops canker sore is dedicated, the effective ingredient of formula is mainly mutually compounded with the extract of the plants such as natural propolis and fritillaria, Radix Astragali, honeysuckle, aloe, cloves, Radix Isatidis, the canker sore drops with antibacterial, antiinflammation is made through special process, and inhibit the growth of pathogenic bacteria in oral cavity, it is suitable for a series of heredity canker sore patient health disease areas such as canker sore, aphthae, oral lesions.Present invention is generally directed to there are canker sore recurrent exerbations not specifically for property in market, and stimulating to mucous membrane of mouth at branch containing chemical stimulation, contained perfume ingredient can not fundamentally dispel the pathogenic bacteria of canker sore, microorganism even contained by some canker sore product itselfs just severely exceeds, the disadvantages of serious health for jeopardizing people, special use has antibacterial, the natural propolis and pure plant of antiinflammation are extracted into split-phase compounding, a kind of dedicated propolis drops of plant type canker sore is made, fundamentally dispel the pathogenic bacteria of canker sore, prevent canker sore recurrence, it is pollution-free, it is safe and healthy, it is easy to use.
Description
Technical field is the present invention relates to a kind of propolis drops canker sore is dedicated, and the effective ingredient of formula is mainly with natural
The extract of the plants such as propolis and fritillaria, Radix Astragali, honeysuckle, aloe, cloves, Radix Isatidis mutually compounds, and tool is made through special process
There is the canker sore drops of antibacterial, antiinflammation, and inhibit the growth of pathogenic bacteria in oral cavity, is suitable for canker sore, dispute life
The a series of heredity canker sore patient health disease areas such as sore, oral lesions.Canker sore is oral cavity common at present
One of disease, also someone is known as " aphtha ", is a kind of shallow and small, round or oval ulcer.Most common one in canker sore
It kind is " recurrent oral ulceration ", it is usually raw on lip, tongue or other positions in oral cavity, and can often recur.Therefore,
It is a that for canker sore and the recurrence of prevention canker sore, to have the propolis drops canker sore special product of very good effect be people
Eager demand.Present invention is generally directed to there are canker sore recurrent exerbations in market not specifically for property, and containing changing
Learn it is irritating at branch's stimulation to mucous membrane of mouth, contained perfume ingredient can not fundamentally dispel the cause of canker sore
Microorganism contained by germ or even some canker sore product itselfs just severely exceeds, the serious body for jeopardizing people
It is the disadvantages of healthy, special using having antibacterial, the natural propolis of antiinflammation and pure plant to be extracted into split-phase compounding, one kind is made
The dedicated propolis drops of plant type canker sore fundamentally dispels the pathogenic bacteria of canker sore, prevention canker sore recurrence, nothing
Pollution, it is safe and healthy, it is easy to use.
The appearance of background technique canker sore causes many inconvenience to our life, and causes the factor of canker sore
Mainly have: (1), disease of digestive system and dysfunction (2), hormonal change (3), mental element (4), other factors: as lacked
Weary trace element zinc, iron, folic acid, vitamin B12, malnutrition etc., can reduce immune function, increase cause canker sore because
A possibility that element morbidity；The bacteriums such as Streptococcus sanguis and helicobacter pylori are also in close relations with canker sore.Canker sore is usually pre-
Show that body may have potential systemic disease, canker sore and gastric ulcer, duodenal ulcer, ulcerative colitis, limitation
Property enteritis, vegetative nerve functional disturbance disease etc. are related.Therefore, a kind of pure natural plant type, can fundamentally dispel oral cavity
The dedicated drops of natural propolis canker sore of pathogenic bacteria is the eager demand of people.It is an object of the invention to provide it is a can
The pathogenic bacteria of mouth disease are fundamentally dispelled, and the generation of the various mouth diseases of canker sore recurrent exerbation can be prevented,
The canker sore drops of the permanent broad-spectrum antibacterial action for keeping propolis.
Summary of the invention is of the invention to be characterized by natural propolis and fritillaria, Radix Astragali, honeysuckle, aloe, cloves, plate indigo plant
The plant extract of root mutually compounds, and improves antibacterial, the antiinflammation of each active constituent, while dispelling mouth disease pathogenic bacteria,
It can prevent the generation of the various mouth diseases of canker sore recurrent exerbation.
The formula that the present invention selects is following (component and its weight percent %): natural propolis 5.0-8.0；Fritillaria 4.0-
7.0；Radix Astragali 2.0-4.0；Honeysuckle 1.0-3.0；Aloe 5.0-7.0；Cloves 3.0-4.0；Radix Isatidis 1.0-3.0；Purified water adds
To 100.
Propolis is a kind of extremely rare natural resources, is known as the title of " purple gold ", the antibacterial having, anti-inflammatory analgetic,
It eliminates fungal infection, promote the effect of cytothesis, the illnesss such as canker sore, gastric ulcer, burn and scald, skin Tearing Pain can be treated,
Abundant and unique bioactive substance contained by propolis makes it have antibacterial, anti-inflammatory, antipruritic, anti-oxidant, enhancing is immune etc.
Multiple functions have extensive medical treatment, health-care effect to human body.Propolis can sterilize, sterilize, sterilizing, is antibacterial, is mould proof, anti-corrosion, solution
The defect that antibiotic of having determined only works to single microorganism, and be free from side effects.Have very to mouth disease in daily life
Good therapeutic effect.Propolis is natural antiviral substance, has very strong inhibition and killing effect, Neng Goujia to a variety of viruses
The healing of fast histocyte regeneration and wound, inhibits the growth of various bacteria and certain viruses, and antibacterial, anti-inflammatory with wide spectrum are made
With.
Fritillaria is herbaceos perennial, and Collective Notes to the Canon of Materia medica is said: " being similar to poly- shellfish ", therefore named fritillaria have stronger
Anti-inflammatory, antiulcer, it is antiviral the effects of.Can clearing heat and detoxicating, dispersing swelling and dissipating binds, the carbuncle that disappears apocenosis, sore swollen toxin function, can be used to treat
Sore, purulence blood, skin swell the diseases such as rotten.
Radix Astragali belongs to state three level protecting plant, has more than 2000 years history, Radix Astragali is sweet in flavor, slightly warm in nature.Beneficial to gas-solid
The effect of table, apocenosis, torr sore myogenic, detumescence.With wide antibacterial, antiulcer and antivirus action.
The general designation of honeysuckle plant, has a clearing heat and detoxicating, broad-spectrum antiseptic and antiviral and other effects, 70% or more flu,
All contain honeysuckle in anti-inflammatory Chinese patent drug.With " Chinese medicine antibiotic ", " title of antibacterial green element.Resisting pathogenic microbes effect.Gold
Honeysuckle flower has certain inhibiting effect to various pathogens such as staphylococcus aureus, Escherichia coli, hemolytic streptococcus etc..To lung
Scorching coccus, Pseudomonas aeruginosa, tubercle bacillus, streptococcus mutans etc. have antibacterial and bactericidal effect, and it is swollen can to treat canker sore, boil
The diseases such as poison, periodontitis, acute and chronic tonsillitis.
Aloe has bactericidal antiphlogistic, enhancing immune function, glue liquid rich in, and this glue liquid has prevention
Ulcer, promotes wound healing, and the effect of stimulating cellular growth and hemostasis can effectively treat each of common skin and body surface
Kind disease.Compendium of Material Medica describes a variety of therapeutic effects of aloe, including bactericidal antiphlogistic, prevention colitis and prevention and treatment digestion
It systemic disease and improves a poor appetite, to protecting our enteron aisles largely effective.Aloe is rich in the prebiotics of needed by human body, and prebiotics can
To supplement " food " to beneficial bacteria of intestinal tract, activation and the intracorporal beneficial flora of proliferation of human are improved strong with promoting microecological balance
Health.Therefore, the aloe water rich in prebiotics helps to improve immunity, protects stomach health.
Cloves has antimycotic, the anti-inflammatory effect of wide spectrum, and cloves contains caryophyllus oil, for pathogenic fungus and staphylococcus,
Dysentery and Escherichia coli etc. have an inhibiting effect, caryophyllus oil, be plant of clove dry flower through distilling resulting volatile oil, can be with
Anti-corrosion, antibacterial and analgesic, are well suited for for preventing disease and inflammation, have good therapeutic effect, cloves to oral cavity, the raw sore of words
The caryophyllus oil bactericide processed of branch distillation.
Radix Isatidis: clearing heat and detoxicating, antiviral, antibacterium, it is sarcine, big right to hay bacillus, staphylococcus aureus
Diplococcus has very strong killing effect.
Effective component of the present invention is that will have the plant extract component of antibacterial action and have anti-inflammation and sterilization, clear
The plant extract of the effects of thermal detoxification mutually compounds, and every kind of ingredient is played power to maximum to antibacterial, anti-inflammatory, collective effect is in prevention
Cause the treatment and nursing of canker sore.
The preparation method of the product of the invention is:
1), that fritillaria, Radix Astragali, honeysuckle, aloe, cloves, Radix Isatidis is spare after over cleaning, drying, crushing respectively；
2), proportionally fritillaria, Radix Astragali, honeysuckle, aloe, cloves, Radix Isatidis and purified water are matched and are added in boiler
Plant mixed liquor is extracted after tanning；
3) plant mixed liquor, is purified into plant extracts using special process；
4) plant extracts and natural propolis are added in agitated kettle according to percentage, stirred 25 minutes；
5), stop stirring, it is canned to can be used after filtering, standing 24 as a child.
The invention has the following advantages that
(1) with the antibacterial of natural propolis and plant extracts, anti-inflammation components, the pathogenic bacteria in oral cavity are quickly dispelled；
(2) promote cytothesis, accelerate the healing rate of wound；
(3) anti-inflammatory, sterilizing rate are high；
(4) clearing heat and detoxicating, torr sore myogenic, apocenosis, detumescence；
(5) safe, non-stimulated.
The present invention is described in further detail below with reference to embodiment for specific embodiment:
It is configured according to data (weight percent %) listed in Table and its step:
Formula one:
Natural propolis 5.0-8.0；Fritillaria 4.0-7.0；Radix Astragali 2.0-4.0；Honeysuckle 1.0-3.0；Aloe 5.0-7.0；Cloves
3.0-4.0；Radix Isatidis 1.0-3.0；Purified water adds to 100.
Formula two:
Natural propolis 5.0-6.5；Fritillaria 4.0-5.5；Radix Astragali 2.0-3.0；Honeysuckle 1.0-2.0；Aloe 5.0-6.0；Cloves
3.0-3.5；Radix Isatidis 1.0-2.0；Purified water adds to 100.
Formula three:
Natural propolis 6.5-8.0；Fritillaria 5.5-7.0；Radix Astragali 3.0-4.0；Honeysuckle 2.0-3.0；Aloe 6.0-7.0；Cloves
3.5-4.0；Radix Isatidis 1.5-3.0；Purified water adds to 100.
Claims (2)
1. a kind of propolis drops canker sore is dedicated, it is characterised in that have as following formula (component and its weight percent %):
Natural propolis 5.0-8.0；Fritillaria 4.0-7.0；Radix Astragali 2.0-4.0；Honeysuckle 1.0-3.0；Aloe 5.0-7.0；Cloves 3.0-
4.0；Radix Isatidis 1.0-3.0；Purified water adds to 100.
2. the dedicated preparation method of propolis drops canker sore described in a kind of claim 1, it is characterised in that have following step
It is rapid:
1), that fritillaria, Radix Astragali, honeysuckle, aloe, cloves, Radix Isatidis is spare after over cleaning, drying, crushing respectively；
2), proportionally fritillaria, Radix Astragali, honeysuckle, aloe, cloves, Radix Isatidis and purified water are matched and are added in boiler
Plant mixed liquor is extracted after tanning；
3) plant mixed liquor, is purified into plant extracts using special process；
4) plant extracts and natural propolis are added in agitated kettle according to percentage, stirred 25 minutes；
5), stop stirring, it is canned to can be used after filtering, standing 24 as a child.
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| CN201710569843.7A CN109248255A (en) | 2017-07-13 | 2017-07-13 | Propolis drops canker sore is dedicated |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115252690A (en) * | 2022-08-05 | 2022-11-01 | 河北东医生物科技有限公司 | Chinese herbal medicine for improving antibacterial capacity of oral mucosa and preparation method thereof |
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2017
- 2017-07-13 CN CN201710569843.7A patent/CN109248255A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115252690A (en) * | 2022-08-05 | 2022-11-01 | 河北东医生物科技有限公司 | Chinese herbal medicine for improving antibacterial capacity of oral mucosa and preparation method thereof |
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Application publication date: 20190122 |