CN104491426A - Emulsion medicine capable of quickly relieving pain and treating scalds and burns and preparation method of emulsion medicine - Google Patents
Emulsion medicine capable of quickly relieving pain and treating scalds and burns and preparation method of emulsion medicine Download PDFInfo
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- CN104491426A CN104491426A CN201410743001.5A CN201410743001A CN104491426A CN 104491426 A CN104491426 A CN 104491426A CN 201410743001 A CN201410743001 A CN 201410743001A CN 104491426 A CN104491426 A CN 104491426A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Abstract
The invention belongs to medicine liquid capable of treating boiling water scalds or fire burns and in particular relates to an emulsion medicine capable of quickly relieving pain and treating scalds and burns and a preparation method of the emulsion medicine. The emulsion medicine capable of treating scalds and burns comprises the following components in parts by weight: 0.5-3.0 parts of chlorogenic acid, 0.02-0.2 part of a prickly ash extract, 0.2 part of a bletilla extract, 2.5 parts of borneol, 0.10 part of quick lime, 1.0-2.0 parts of tea oil and 100 parts of water. The components are uniformly mixed to prepare white emulsion liquid which is the emulsion medicine. The medicine liquid has the advantages of being capable of quickly relieving pain, quick in curative effect, capable of treating the scalds of first degree-deep second degree and free of scar.
Description
Technical field
The invention belongs to a kind of liquid medicine for the treatment of boiled water scald or fire burn, be specifically related to the treatment of a kind of quick-acting antalgesic and scald emulsion medicine of burn and preparation method thereof.
Background technology
Burn, also known as scald, is a kind of common surgery acute injury, mainly refers to the damage that body is caused by flame, high-temp solid and intense radiation heat.The degree of burn is by the height of temperature, the length of action time and different.
In general, the scald run in people's daily life is common is boiled water scald or burning hot wound, and scald can be divided into I degree, shallow II degree, dark II degree and III degree four grades: I degree: congested because of angioparalysis; Shallow II degree: form the burn hydatoncus being full of serum: dark II degree: tissue necrosis; III degree: the carbonization of tissue.Lactic acid production during burn in visible blood increases, and the pH value of arteriovenous blood reduces, and also increases weight along with organizing the handicapped anoxemia (anoxemia) that increases the weight of of blood capillary thereupon.
Clinical experience proves, then can be in peril of one's life when burn reaches more than 1/2nd of total body surface area.The tissue of burn may be downright bad, and during tissue bums, endovascular liquid oozes out and causes tissue edema.During large-area burns, Vascular permeability sexual abnormality, loses large quantity of fluid, may cause shock, and during shock, blood pressure is very low, and the blood flow minimizing flowing to brain and other vitals directly works the mischief to life.Further, fire victim may cause and disfeature or maimed person after treatment, and severe patient even causes dies young, and brings misfortune to the life of people.The medicine of existing treatment burn is a lot, but the shortcoming that ubiquity cost is high, and concerning inapplicable the rural population of economic condition difference, and treatment cycle is long, and therapeutic effect is undesirable, easy scar.
Summary of the invention
An object of the present invention is for the high shortcoming of existing treatment liquid medicine treatment cost, provides a kind of novel quick-acting antalgesic to treat the emulsion medicine scalding burn.This liquid medicine have analgesia rapidly, treatment speed is fast, can treat I degree---deep II degree burn wound, advantage without cicatrix.
The emulsion medicine of burn is scalded in quick-acting antalgesic treatment of the present invention, comprise the component of following content: the chlorogenic acid of 0.5 ~ 3.0 weight portion, the Fructus Zanthoxyli extract of 0.02 ~ 0.2 weight portion, the bletilla striata extract of 0.2 weight portion, the Borneolum Syntheticum of 2.5 weight portions, the quicklime of 0.10 weight portion, the Oleum Camelliae of 1.0 ~ 2.0 weight portions, the water of 100 weight portions.
Two of object of the present invention is to provide above-mentioned quick-acting antalgesic to treat the preparation method of the emulsion medicine scalding burn, the method is: by the Oleum Camelliae of the quicklime of the Borneolum Syntheticum of the bletilla striata extract of the Fructus Zanthoxyli extract of the chlorogenic acid of 0.5 ~ 3.0 weight portion, 0.02 ~ 0.2 weight portion, 0.2 weight portion, 2.5 weight portions, 0.10 weight portion, 1.0 ~ 2.0 weight portions, the water Homogeneous phase mixing of 100 weight portions, obtain white " milky " liquid, obtain product.
The pharmacological property of each component of the present invention is as follows:
Chlorogenic acid, its chemical name is CA.Extensively be present in Flos Lonicerae, Folium Eucommiae, Xiang Gui, Herba Artemisiae Scopariae, leaf of Semen Maydis, coffee, Folium Camelliae sinensis and Folium Ipomoea.Chlorogenic acid is a kind of broad spectrum antimicrobicide, not only have and have strong inhibitory action to multiple pathogenic bacteria such as staphylococcus aureus etc., also have antiinflammatory, hemostasia effect, the more important thing is, chlorogenic acid contains a kind of skin, skeleton, the special composition of the composition and decomposition of glue protein in muscle that promote human body, the Pseudobulbus Bletillae (Rhizoma Bletillae) coordinates with it, and its granulation promoting effect significantly improves.
Pericarpium Zanthoxyli is conventional Chinese crude drug, and have strong dehematizing and go out that scar, blood coagulation are antipruritic, antibacterial, granulation promoting drug effect, the composition such as Pericarpium Zanthoxyli brain, sanshoamide in Fructus Zanthoxyli extract has very strong persistence analgesia, antiinflammatory action.Itching is common sympton in burn and scald therapeutic process, especially skin growth period, very itches unbearably, the misery of most (child) patients because being itched unbearably, grab with hands or other modes antipruritic, result causes serious sequela.This medicine can remove these miseries of patient effectively.
The Pseudobulbus Bletillae (Rhizoma Bletillae) has effect of astringing to arrest bleeding, detumescence and promoting granulation.Be used to the conventional Chinese medicine simply for the treatment of interior external haemorrhage, scald, rhagadia manus et pedis.
Borneolum Syntheticum is mainly containing Borneolum Syntheticum (59.78% ~ 58.93%), isoborneol (38.98% ~ 37.52%) and Camphora (2.70% ~ 2.09%), and it has antibacterial, antiinflammatory action.Meanwhile, Borneolum Syntheticum can make skin produce refrigerant sense, eliminates causalgia sense.
Quicklime, after water-soluble, with Ca (OH)
2form exists, and calcium ion has astriction, has and promotes incrustation and wound healing; Meanwhile, Ca (OH)
2alkalescence, can in and the fatty acid of Oleum Camelliae Emulsion hydrolysis, regulate the pH effect of medicinal liquid.
Containing flavone and abundant natural Vitamin E in Oleum Camelliae, there is fine moisturizing, antiinflammatory, antibacterial, analgesic effect.
The emulsion formed by Oleum Camelliae-water, has promotion skin (human body) to the effect of drug absorption, accelerates wound healing; In addition, the easy to use and Wound treatment of this medicinal liquid, alleviates patient suffering.
Using method and the points for attention of liquid medicine of the present invention are as follows: glue this medicine with feather harder on cotton swab or Duck wing and to dab in affected part and smoothen.The holding conditions of this product: sealing is positioned over the storage of 0 DEG C, refrigerator degree.The sex character of this product is as follows: white " milky " liquid.This product cures mainly following symptom: the following small-area burn of II level, scald and wound.
The therapeutic effect that the emulsion medicine of burn is scalded in quick-acting antalgesic treatment of the present invention is as follows:
(1) have quickly alleviating pain, refrigerant effect, in medication process, affected part is without the sensation of significant discomfort or other chafes;
(2) healing rate is fast, and to I degree---deep II degree burn wound is effective, wound healing is fast, small size trauma skin normal healing, preventing from scar.
The treatment liquid medicine that the invention provides a kind of novel therapeutic burn and scald, preparation method is simple, also scalds burn medicine for people provide the external that a kind of house is standing, price is suitable, effective.
Detailed description of the invention
Here is concrete preparation embodiment of the present invention.In the present invention, medical material used all can be buied in market.
Embodiment 1:
By 3.0g chlorogenic acid, 0.02g Fructus Zanthoxyli extract, 0.2g bletilla striata extract, 2.5g Borneolum Syntheticum, 0.10g quicklime, 2.0g Oleum Camelliae, 100g water Homogeneous phase mixing, obtain product, this product appearance is white " milky " liquid.
Embodiment 2:
By 2.0g chlorogenic acid, 0.05g Fructus Zanthoxyli extract, 0.2g bletilla striata extract, 2.5g Borneolum Syntheticum, 0.10g quicklime, 2.0g Oleum Camelliae, 100g water Homogeneous phase mixing, obtain product, this product appearance is white " milky " liquid.
Embodiment 3:
By 1.0g chlorogenic acid, 0.1g Fructus Zanthoxyli extract, 0.2g bletilla striata extract, 2.5g Borneolum Syntheticum, 0.10g quicklime, 2.0g Oleum Camelliae, 100g water Homogeneous phase mixing, obtain product, this product appearance is white " milky " liquid.
Embodiment 4:
By 0.5g chlorogenic acid, 0.2g Fructus Zanthoxyli extract, 0.2g bletilla striata extract, 2.5g Borneolum Syntheticum, 0.10g quicklime, 1.0g Oleum Camelliae, 100g water Homogeneous phase mixing, obtain product, this product appearance is white " milky " liquid.
Embodiment 5:
By 1.5g chlorogenic acid, 0.1g Fructus Zanthoxyli extract, 0.2g bletilla striata extract, 2.5g Borneolum Syntheticum, 0.10g quicklime, 1.0g Oleum Camelliae, 100g water Homogeneous phase mixing, obtain product, this product appearance is white " milky " liquid.
Here is the Clinic Case of liquid medicine of the present invention:
Case one: Tan, man, 10 years old, the left hand palm of burning when putting fireworks, was deep ii degree burn (hospital diagnosis).Use the liquid medicine of the embodiment of the present invention 4 to carry out right-falling stroke to be coated with, incrustation in 5 days, starts decrustation after using 2 weeks, and recovery from illness in 32 days, wound surface does not stay cicatrix.
Case two: Zhang, man, 37 years old, out of doors by fire burn.In a health left side then (left side is arm and left lower limb and waist then), left arm and waist are mainly minor burn to main burned part, and the dark II degree (hospital diagnosis) in left lower limb local, total wound surface is about 120cm
2, use the liquid medicine of the embodiment of the present invention 3 to carry out right-falling stroke and be coated with, pain relieving at once.Left arm and waist wound surface, be coated with and use this medicine, recovery from illness in 7 days; To burn comparatively serious position 38 days recovery from illness; All without cicatrix.
Case three: Chen, female, 4 years old, is scalded right arm by boiled water, red and swollen, bubbles, and pain is severe; Use the liquid medicine of the embodiment of the present invention 1 to treat, pain relieving at once, recovery from illness in 7 days, wound surface does not stay cicatrix.
Claims (6)
1. the emulsion medicine of burning is scalded in a quick-acting antalgesic treatment, it is characterized in that the component comprising following content: the chlorogenic acid of 0.5 ~ 3.0 weight portion, the Fructus Zanthoxyli extract of 0.02 ~ 0.2 weight portion, the bletilla striata extract of 0.2 weight portion, the Borneolum Syntheticum of 2.5 weight portions, the quicklime of 0.10 weight portion, the Oleum Camelliae of 1.0 ~ 2.0 weight portions, the water of 100 weight portions.
2. the emulsion medicine of burn is scalded in quick-acting antalgesic treatment according to claim 1, it is characterized in that the component comprising following content: the chlorogenic acid of 3.0 weight portions, the Fructus Zanthoxyli extract of 0.02 weight portion, the bletilla striata extract of 0.2 weight portion, the Borneolum Syntheticum of 2.5 weight portions, the quicklime of 0.10 weight portion, the Oleum Camelliae of 2.0 weight portions, the water of 100 weight portions.
3. the emulsion medicine of burn is scalded in quick-acting antalgesic treatment according to claim 1, it is characterized in that the component comprising following content: the chlorogenic acid of 2.0 weight portions, the Fructus Zanthoxyli extract of 0.05 weight portion, the bletilla striata extract of 0.2 weight portion, the Borneolum Syntheticum of 2.5 weight portions, the quicklime of 0.10 weight portion, the Oleum Camelliae of 2.0 weight portions, the water of 100 weight portions.
4. the emulsion medicine of burn is scalded in quick-acting antalgesic treatment according to claim 1, it is characterized in that the component comprising following content: the chlorogenic acid of 1.0 weight portions, the Fructus Zanthoxyli extract of 0.1 weight portion, the bletilla striata extract of 0.2 weight portion, the Borneolum Syntheticum of 2.5 weight portions, the quicklime of 0.10 weight portion, the Oleum Camelliae of 2.0 weight portions, the water of 100 weight portions.
5. the emulsion medicine of burn is scalded in quick-acting antalgesic treatment according to claim 1, it is characterized in that the component comprising following content: the chlorogenic acid of 0.5 weight portion, the Fructus Zanthoxyli extract of 0.2 weight portion, the bletilla striata extract of 0.2 weight portion, the Borneolum Syntheticum of 2.5 weight portions, the quicklime of 0.10 weight portion, the Oleum Camelliae of 1.0 weight portions, the water of 100 weight portions.
6. one kind as claimed in claim 1 quick-acting antalgesic treatment scald the preparation method of emulsion medicine of burn, it is characterized in that: by the Oleum Camelliae of the quicklime of the Borneolum Syntheticum of the bletilla striata extract of the Fructus Zanthoxyli extract of the chlorogenic acid of 0.5 ~ 3.0 weight portion, 0.02 ~ 0.2 weight portion, 0.2 weight portion, 2.5 weight portions, 0.10 weight portion, 1.0 ~ 2.0 weight portions, the water Homogeneous phase mixing of 100 weight portions, obtain white " milky " liquid, obtain product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410743001.5A CN104491426A (en) | 2014-12-08 | 2014-12-08 | Emulsion medicine capable of quickly relieving pain and treating scalds and burns and preparation method of emulsion medicine |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410743001.5A CN104491426A (en) | 2014-12-08 | 2014-12-08 | Emulsion medicine capable of quickly relieving pain and treating scalds and burns and preparation method of emulsion medicine |
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| CN104491426A true CN104491426A (en) | 2015-04-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410743001.5A Pending CN104491426A (en) | 2014-12-08 | 2014-12-08 | Emulsion medicine capable of quickly relieving pain and treating scalds and burns and preparation method of emulsion medicine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343332A (en) * | 2015-11-23 | 2016-02-24 | 湖南科技大学 | Herba artemisiae capillariae rhizoma polygoni cuspidati ointment, and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099994A (en) * | 1994-04-27 | 1995-03-15 | 王乐锋 | Burns regeneration extract |
| CN101485681A (en) * | 2009-03-01 | 2009-07-22 | 卢金彪 | Medicament for treating burn and scald, and preparation method thereof |
| CN104127690A (en) * | 2014-07-08 | 2014-11-05 | 韩城市秦龙花椒科技有限责任公司 | Chinese prickly ash-containing traditional Chinese medicine compound hemostasis powder for treating wounds |
-
2014
- 2014-12-08 CN CN201410743001.5A patent/CN104491426A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099994A (en) * | 1994-04-27 | 1995-03-15 | 王乐锋 | Burns regeneration extract |
| CN101485681A (en) * | 2009-03-01 | 2009-07-22 | 卢金彪 | Medicament for treating burn and scald, and preparation method thereof |
| CN104127690A (en) * | 2014-07-08 | 2014-11-05 | 韩城市秦龙花椒科技有限责任公司 | Chinese prickly ash-containing traditional Chinese medicine compound hemostasis powder for treating wounds |
Non-Patent Citations (1)
| Title |
|---|
| 周德喜: "烧烫伤验方", 《湖南中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343332A (en) * | 2015-11-23 | 2016-02-24 | 湖南科技大学 | Herba artemisiae capillariae rhizoma polygoni cuspidati ointment, and preparation method thereof |
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Application publication date: 20150408 |