CN106491455A - A kind of composition and its application containing butterfly bush extract - Google Patents
A kind of composition and its application containing butterfly bush extract Download PDFInfo
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- CN106491455A CN106491455A CN201611168359.5A CN201611168359A CN106491455A CN 106491455 A CN106491455 A CN 106491455A CN 201611168359 A CN201611168359 A CN 201611168359A CN 106491455 A CN106491455 A CN 106491455A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses a kind of composition and its application containing butterfly bush extract, aim to provide a kind of moist performance of keeping humidity notable, skin water content can stably be pinned, strengthen cell self moisturizing function, corneocyte water content is effectively lifted, and is effectively improved skin barrier function, prevent water loss, skin irritant composition is reduced, said composition is mainly made up of following components in parts by weight：20 70 parts of butterfly bush extract；10 30 parts of alga combined extract；The alga combined extract is made up of the raw material of following parts by weight：12 30 parts of undaria pinnitafida；10 20 parts of yellow tang；30 40 parts of bladder-wrack；Fur 30 40 parts of algae of pine；10 16 parts of kappaphycus alvarezi；Belong to cosmetic field.
Description
Technical field
The present invention relates to a kind of composition, specifically, is to be related to a kind of composition containing butterfly bush extract, this
Invention further relates to this composition as the application of skin-care product additive, belongs to cosmetic field.
Background technology
In recent years, the skin care item of efficiency natural increasingly obtain the accreditation of consumer, and wherein marine natural product is for people
The validity of class skin has obtained the accreditation of authoritative institution of the world, and a lot of scientific achievements have been widely used for cosmetics neck
Domain.Compared with traditional plant or artificial biochemical cosmetic composition, marine natural product is not only natural, efficient, and is more suitable for
Percutaneous absorption.
At present, most widely used non-algae in marine natural product does not belong to.Algae is in the face of marine extreme environment (such as height
Salt, high pressure, solar radiation etc.) evolve and advanced resist mechanism.And different algal species extract can bring moisturizing tender to skin
Skin, whitening are purified, sun-proof different skin makeup effect such as anti-aging.
Skin makeup effect of algae extract is unquestionable, and selects suitable algae, therefrom isolate suitable activity into
Point, and efficient, safe composition is prepared, ultimately join, be not only
The focus of industry development, and be the difficult point that industry development needs to solve.
Content of the invention
For the problems referred to above, the first object of the present invention is to provide a kind of moist performance of keeping humidity significantly, can stably pin flesh
Skin water content, strengthens cell self moisturizing function, effectively lifts corneocyte water content, and is effectively improved skin barrier
Function, prevents water loss, reduces the skin irritant composition containing butterfly bush extract.The second object of the present invention is
Application of this composition containing butterfly bush extract as skin-care product additive is provided.
For solving first technical problem, first technical scheme that the present invention is provided is such：
A kind of composition containing butterfly bush extract, is mainly made up of following components in parts by weight：Butterfly bush
Extract 20-70 parts；Alga combined extract 10-30 parts；
The alga combined extract is made up of the raw material of following weight portion：Undaria pinnitafida 12-30 parts；Yellow tang 10-20 parts；
Bladder-wrack 30-40 parts；Fur pine algae 30-40 parts；Kappaphycus alvarezi 10-16 part.
Further, a kind of composition containing butterfly bush extract, the alga combined extract also include
The raw material of following weight portion：Sargassum 10-20 parts；Sea lettuce 15-40 parts.
Further, a kind of composition containing butterfly bush extract, the composition also include following weight
The component of part：Cotton extract 5-50 parts；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 20-30 parts.
Further, a kind of composition containing butterfly bush extract, described composition is by following weight parts
Component make：Butterfly bush extract 30-60 parts；Cotton extract 10-40 parts；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 20-30 parts；Algae
Class composite extract 20-30 parts；
The alga combined extract is made up of the raw material of following weight portion：Undaria pinnitafida 15-20 parts；Yellow tang 10-20 parts；
Bladder-wrack 30-40 parts；Fur pine algae 30-40 parts；Kappaphycus alvarezi 10-15 part；Sargassum 10-20 parts；Sea lettuce 30-40 parts.
Further, a kind of composition containing butterfly bush extract, the preparation method of the composition include
Following steps：
1) algae raw material of formula consumption is dried first with clean water, crushes, mix, with solid-to-liquid ratio 1g/30ml-5g/
30ml is mixed with distilled water, is transferred in ultra high pressure extraction tank, under normal temperature condition, is pressurized to 100-300MPa, pressurize 5-
10min, after reaching the dwell time, extract is taken out in release in the 2-3s；
2) by step 1) extract that obtains is centrifuged 10-20min with rotating speed 5000-10000r/min, takes supernatant,
20-40bar, carries out nanofiltration desalination process under conditions of temperature 10-30 DEG C, the molecular cut off of NF membrane is 100-200Da, then
Filter vacuum is concentrated, alga combined extract is obtained；
3), after be well mixed the butterfly bush extract of formula consumption with alga combined extract, it is spray-dried, i.e.,
?.
Preferably, the step 3) also include by 5-50 part cotton extracts and 20-30 part wedge bases Thallus Laminariae (Thallus Eckloniae) extract with match somebody with somebody
The butterfly bush extract of square consumption and the mixing of alga combined extract.
Preferably, the step 3) spray drying EAT be 180-200 DEG C, atomizing pressure is 0.1-
0.2Mpa, charging rate are 600-800ml/h.
Second technical scheme that the present invention is provided is as skin care using the composition containing butterfly bush extract
The application of product additive.
Compared with prior art, the technical scheme that the present invention is provided has the advantages that：
1st, the alga combined extract that the present invention is provided passes through undaria pinnitafida, yellow tang, bladder-wrack, fur pine algae, the long heart
Kappa algae is acted synergistically with butterfly bush extract, can be helped moist skin, is that skin brings lasting moisturizing to imitate
Really.
Compound with sargassum and sea lettuce again on this basis, further can stably pin skin water content, in advance
Anti- water loss, strengthens cell self moisturizing function.
2nd, the present invention is provided butterfly bush extract, cotton extract and wedge base Thallus Laminariae (Thallus Eckloniae) extract three collaboration, have
Effect lifts corneocyte water content, improves skin barrier function, reduces the stimulation of skin.
Specific embodiment
With reference to specific embodiment, the claim of the present invention is described in further detail, but do not constitute right
Any restriction of the present invention, the modification of anyone limited number of time made in the claims in the present invention protection domain etc still exist
Within the claims of the present invention.
It should be noted that the raw material employed in the technical scheme of present invention offer, unless otherwise specified, by often
Rule means are prepared or are bought by commercial channel.
Butterfly bush extract is purchased in DSM (China) Co., Ltd；Cotton extract is purchased in Guangzhou Rong Daoization
Work Co., Ltd；Wedge base Thallus Laminariae (Thallus Eckloniae) extract is purchased in hundred Hao Bo Co., Ltds of Guangzhou.
Embodiment 1
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 20g；Alga combined extract 30g；The alga combined extract is made up of the raw material of following mass number：
Undaria pinnitafida 12g；Yellow tang 20g；Bladder-wrack 30g；Fur pine algae 40g；Kappaphycus alvarezi 10g.
Embodiment 2
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 70g；Alga combined extract 10g；The alga combined extract is made up of the raw material of following mass number：
Undaria pinnitafida 30g；Yellow tang 10g；Bladder-wrack 40g；Fur pine algae 30g；Kappaphycus alvarezi 16g.
Embodiment 3
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 50g；Alga combined extract 20g；The alga combined extract is made up of the raw material of following mass number：
Undaria pinnitafida 20g；Yellow tang 15g；Bladder-wrack 35g；Fur pine algae 35g；Kappaphycus alvarezi 13g.
Embodiment 4
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 30g；Alga combined extract 25g；The alga combined extract is made up of the raw material of following mass number：
Undaria pinnitafida 15g；Yellow tang 18g；Bladder-wrack 36g；Fur pine algae 32g；Kappaphycus alvarezi 15g；Sargassum 10g；Sea lettuce 40g.
Embodiment 5
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 25g；Alga combined extract 25g；The alga combined extract is made up of the raw material of following mass number：
Undaria pinnitafida 13g；Yellow tang 16g；Bladder-wrack 32g；Fur pine algae 36g；Kappaphycus alvarezi 11g；Sargassum 20g；Sea lettuce 15g.
Embodiment 6
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 35g；Alga combined extract 15g；The alga combined extract is made up of the raw material of following mass number：
Undaria pinnitafida 25g；Yellow tang 12g；Bladder-wrack 30g；Fur pine algae 40g；Kappaphycus alvarezi 15g；Sargassum 15g；Sea lettuce 25g.
Embodiment 7
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 40g；Cotton extract 30g；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 30g；Alga combined extract 18g；The algae
Composite extract is made up of the raw material of following mass number：Undaria pinnitafida 14g；Yellow tang 13g；Bladder-wrack 39g；Fur pine algae 33g；Long
Heart Kappa algae 12g.
Embodiment 8
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 60g；Cotton extract 5g；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 20g；Alga combined extract 14g；The algae is multiple
Close extract to be made up of the raw material of following mass number：Undaria pinnitafida 23g；Yellow tang 19g；Bladder-wrack 34g；Fur pine algae 31g；The long heart
Kappa algae 10g.
Embodiment 9
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 55g；Cotton extract 50g；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 25g；Alga combined extract 22g；The algae
Composite extract is made up of the raw material of following mass number：Undaria pinnitafida 28g；Yellow tang 14g；Bladder-wrack 38g；Fur pine algae 34g；Long
Heart Kappa algae 16g.
Embodiment 10
A kind of composition containing butterfly bush extract that the present invention is provided, is made up of the component of following mass numbers：Greatly
Leaf Lindley Butterflybush Herb extract 45g；Cotton extract 40g；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 25g；Alga combined extract 16g；The algae
Composite extract is made up of the raw material of following mass number：Undaria pinnitafida 14g；Yellow tang 11g；Bladder-wrack 31g；Fur pine algae 33g；Long
Heart Kappa algae 14g；Sargassum 15g；Sea lettuce 35g.
In embodiment 1 to 10, the preparation method of the composition containing butterfly bush extract of any one group of offer, passes through
Following step is obtained successively：
1) algae raw material of formula consumption is dried first with clean water, crushes, mix, with solid-to-liquid ratio 1g/30ml-5g/
30ml (preferably 3g/30ml) is mixed with distilled water, is transferred in ultra high pressure extraction tank, under normal temperature condition, is pressurized to 100-
300MPa (preferably 300MPa), pressurize 5-10min (preferably 10min), after reaching the dwell time, release in the 2-3s, taking-up are carried
Take liquid；
2) by step 1) extract that obtains is centrifuged 10- with rotating speed 5000-10000r/min (preferably 8000r/min)
20min (preferably 15min), takes supernatant, under conditions of 20-40bar (preferably 30bar), temperature 10-30 DEG C (preferably 20 DEG C)
Nanofiltration desalination process is carried out, the molecular cut off of NF membrane is 100-200Da (preferably 100Da), then filter vacuum is concentrated, and obtains
Arrive alga combined extract；
3), after be well mixed the extract of formula consumption with alga combined extract, it is spray-dried, obtains final product.Wherein, spray
The EAT that mist is dried is 180-200 DEG C (preferably 200 DEG C), and atomizing pressure is 0.1-0.2Mpa (preferably 0.15Mpa), feeds
Speed is 600-800ml/h (preferably 700ml/h).
In order to better illustrate beneficial effects of the present invention, one kind that present invention offer is given below is carried containing butterfly bush
Take the checking test of the composition of thing：
First, excitant test
In order to verify the excitant of the present invention, test sample prepared by embodiment of the present invention 1-10 is sent to third party's detection
Detection skin irritation, to each test sample with the continuous skin irritation test of 6 chicken embryos, and the chicken embryo of test group goes out
Blood, blood coagulation and the blood vessel time of melting are above 300 minutes.
As a result show, test sample prepared by above-described embodiment is calculated to stimulate scoring to be zero, and this is described
Test sample prepared by bright embodiment 1-10 is nonirritant product.
2nd, efficacy test
(1) with regard to the comparative example of efficacy test
Comparative example 1
Only contain Essence matrix.
Comparative example 2
The a certain commercially available moisturizing essence of purchase.
Comparative example 3
Butterfly bush extract is not contained, remaining is same as in Example 10.
Comparative example 4
Alga combined extract is not contained, remaining is same as in Example 10.
Comparative example 5
, without yellow tang and fur pine algae, remaining is same as in Example 10 for alga combined extraction raw material.
(2) with regard to the preparation of test sample
First, the composition of embodiment 2,4,8,10 and comparative example 3-5 is added separately in Essence matrix, is made
Essence.
Wherein：The mass ratio 4 of composition and Essence matrix:96.
The Essence matrix is the conventional use of Essence matrix of this area Essence, based on gross mass 100g, each group
Divide and its content is shown in Table 1：
Table 1
Essence Matrix formulation procedure：
The deionized water in A phases is heated to 80-90 DEG C first, A phase clouts is subsequently adding, is uniformly dispersed, and homogeneous is to nothing
Particle, when being cooled to 50-60 DEG C, adds B phases to adjust pH to 6-7, continues stirring and be cooled to 45 DEG C, add C phases, stir,
It is cooled to 35 DEG C to obtain final product.
The preparation method of Essence is：
Composition in any one to 2,4,8,10 and comparative example 3-5 group is added above-mentioned A phases and B together with above-mentioned C phases
In the mixture for mutually preparing, stir, be cooled to 35 DEG C and obtain final product Essence.
(3) performance of keeping humidity test
1st, test population：The experimenter of 90 Dries, age 20-60 year, sex are random, are divided into 9 groups, per group 10
People.
2nd, method of testing：
1) technical staff tests the test position that Corneometer CM825 measure experimenter using moisture content of skin, takes
Mean value, is designated as blank value.
2) experimenter uses moisture content of skin by technical staff after continuously using test sample 0.5h, 1h, 2h, 4h, 6h
Test Corneometer CM825 are measured 5 times, are averaged, and are recorded numerical value, be the results are shown in Table 2；Following formula calculated hydration rate is used again,
The results are shown in Table 3.
Hydration rate={ (test value-blank value)/blank value } × 100%
3) experimenter measures hand using the lost analyzer TM300 of transepidermal water after continuously using test sample one month
Butt skin water loss amount [TEWL, g/ (h m2)], TEWL values can reflect that the effect for improving skin barrier function, TEWL values are got over
Low, moisture loss is fewer, shows that skin barrier function is better.The results are shown in Table 4.
2 moisture test result of table
3 hydration rate test result of table
| Test sample | 0h | 0.5h | 1h | 2h | 4h | 6h |
| 2 Essence of embodiment | 0 | 79.20 | 64.67 | 53.05 | 46.06 | 41.25 |
| 4 Essence of embodiment | 0 | 81.60 | 65.67 | 54.26 | 48.12 | 44.39 |
| 8 Essence of embodiment | 0 | 83.94 | 66.86 | 57.97 | 50.27 | 46.34 |
| 10 Essence of embodiment | 0 | 87.18 | 69.40 | 60.26 | 52.59 | 48.43 |
| 1 Essence matrix of comparative example | 0 | 30.08 | 24.54 | 20.77 | 13.27 | 6.12 |
| 2 commercially available moisturizing essence of comparative example | 0 | 46.25 | 37.49 | 30.88 | 23.38 | 15.32 |
| 3 Essence of comparative example | 0 | 69.88 | 53.56 | 42.85 | 38.66 | 35.27 |
| 4 Essence of comparative example | 0 | 47.36 | 38.02 | 31.24 | 24.37 | 16.78 |
| 5 Essence of comparative example | 0 | 70.31 | 55.42 | 44.46 | 40.15 | 35.81 |
4 moisture of skin windage TEWL values of table
Result above shows that Essence prepared by 2,4,8,10 composition of the embodiment of the present invention has good moisture retention
Can, and skin barrier function can be significantly improved, reduce the water loss amount of skin.
Particularly, after the Essence using interpolation 10 composition of embodiment, its moisture is apparently higher than embodiment 2,4,8
The commercially available moisturizing essence of Essence, the Essence matrix of comparative example 1 and comparative example 2 prepared by composition, comparative example 3-5 composition
Magnificent liquid, TEWL values are significantly lower than Essence, the essence of comparative example 1 prepared by 2,4,8 composition of embodiment, comparative example 3-5 composition
Magnificent liquid-based matter and the commercially available moisturizing essence of comparative example 2.
As can be seen here, in undaria pinnitafida, yellow tang, bladder-wrack, fur pine algae, kappaphycus alvarezi, sargassum, seven kinds of algaes of sea lettuce
On the basis of class synergy then multiple with butterfly bush extract, cotton extract, three kinds of extracts of wedge base Thallus Laminariae (Thallus Eckloniae) extract
Match somebody with somebody, its performance of keeping humidity and improve skin barrier function and obtain significant Synergistic, reach performance of keeping humidity preferably, can be effectively improved
Skin barrier function, reduces moisture loss.
And the moisture of comparative example 3 is also relatively lower than the Essence prepared using 10 composition of embodiment, illustrate big
Yellow tang in leaf Lindley Butterflybush Herb extract, alga combined extract and alga combined extraction raw material and fur pine algae and other
Composition is cooperateed with, and to the performance of keeping humidity of the composition of the present invention and is improved skin barrier function and is played an important role.
And experimenter adhered to the test sample prepared using the present invention after 3 months, without there are not facial sufferings, red
The allergic symptoms such as swollen, oedema, inflammation.
(4) sensory evaluation test
In order to evaluate the using effect of the present composition, 1,5,7,10 composition of Example prepares Essence as examination
Sample is tested, control sample is 2 commercially available moisturizing essence of comparative example.150 20～50 years old experimenters are randomly selected, is divided into 5 groups, per
30 people of group, experimenter adhere to daily using test specimen, carry out sensory evaluation to test specimen, count after 1 month per capita, digital
The number of approral test sample is represented, its result is as shown in table 4.
4 sensory evaluation test result of table
| Test sample | Mildness | Long-acting moisture retention | Moistness |
| 1 Essence of embodiment | 30 people | 22 people | 23 people |
| 5 Essence of embodiment | 30 people | 24 people | 25 people |
| 7 Essence of embodiment | 30 people | 25 people | 26 people |
| 10 Essence of embodiment | 30 people | 29 people | 29 people |
| 2 commercially available moisturizing essence of comparative example | 25 people | 10 people | 15 people |
As a result show, the Essence of the embodiment of the present invention has preferably mildness, long-acting moisture retention and moistness, and
Overall use feeling is also superior to commercially available moisturizing essence.
In sum, the present invention passes through butterfly bush extract, cotton extract, wedge base Thallus Laminariae (Thallus Eckloniae) extract and algae
Composite extract carries out scientific compatibility, and Synergistic moistens performance of keeping humidity significantly, can stably pin skin water content, strengthens
Cell self moisturizing function, effectively lifts corneocyte water content, and is effectively improved skin barrier function, prevent moisture stream
Lose, reduce the stimulation of skin.
Claims (9)
1. a kind of composition containing butterfly bush extract, it is characterised in that be mainly made up of following components in parts by weight：Greatly
Leaf Lindley Butterflybush Herb extract 20-70 parts；Alga combined extract 10-30 parts；
The alga combined extract is made up of the raw material of following weight portion：Undaria pinnitafida 12-30 parts；Yellow tang 10-20 parts；Black angle
Algae 30-40 parts；Fur pine algae 30-40 parts；Kappaphycus alvarezi 10-16 part.
2. a kind of composition containing butterfly bush extract according to claim 1, it is characterised in that the algae is multiple
Closing extract also includes the raw material of following weight portion：Sargassum 10-20 parts；Sea lettuce 15-40 parts.
3. a kind of composition containing butterfly bush extract according to claim 1, it is characterised in that the composition
Also include the component of following weight portion：Cotton extract 5-50 parts；Wedge base Thallus Laminariae (Thallus Eckloniae) extract 20-30 parts.
4. a kind of composition containing butterfly bush extract according to claim 1, it is characterised in that described combination
Thing is made up of following components in parts by weight：Butterfly bush extract 30-60 parts；Cotton extract 10-40 parts；Base sea-tangle carries wedge
Take thing 20-30 parts；Alga combined extract 20-30 parts.
5. a kind of composition containing butterfly bush extract according to claim 1, it is characterised in that the algae is multiple
Close extract to be made up of the raw material of following weight portion：Undaria pinnitafida 15-20 parts；Yellow tang 10-20 parts；Bladder-wrack 30-40 parts；Fur
Loose algae 30-40 parts；Kappaphycus alvarezi 10-15 part；Sargassum 10-20 parts；Sea lettuce 30-40 parts.
6. a kind of composition containing butterfly bush extract according to claim 1, it is characterised in that the composition
Preparation method comprise the steps：
1) algae raw material of formula consumption is dried first with clean water, crushes, mix, with solid-to-liquid ratio 1g/30ml-5g/30ml
Mix with distilled water, be transferred in ultra high pressure extraction tank, under normal temperature condition, be pressurized to 100-300MPa, pressurize 5-10min,
After reaching the dwell time, extract is taken out in release in the 2-3s；
2) by step 1) extract that obtains is centrifuged 10-20min with rotating speed 5000-10000r/min, takes supernatant, in 20-
40bar, carries out nanofiltration desalination process under conditions of temperature 10-30 DEG C, the molecular cut off of NF membrane is 100-200Da, then incites somebody to action
Filter vacuum is concentrated, and obtains alga combined extract；
3), after be well mixed the butterfly bush extract of formula consumption with alga combined extract, it is spray-dried, obtains final product.
7. a kind of composition containing butterfly bush extract according to claim 6, it is characterised in that the step 3)
Also include the butterfly bush extract of 5-50 part cotton extracts and 20-30 part wedge bases Thallus Laminariae (Thallus Eckloniae) extract and formula consumption and
Alga combined extract mixing.
8. a kind of composition containing butterfly bush extract according to claim 6, it is characterised in that the step 3)
Spray drying EAT be 180-200 DEG C, atomizing pressure is 0.1-0.2Mpa, and charging rate is 600-800ml/h.
9. application of a kind of composition containing butterfly bush extract described in claim 1 as skin-care product additive.
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| CN201611168359.5A CN106491455B (en) | 2016-12-16 | 2016-12-16 | Composition containing buddleia davidii extract and application thereof |
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| CN201611168359.5A CN106491455B (en) | 2016-12-16 | 2016-12-16 | Composition containing buddleia davidii extract and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108371639A (en) * | 2018-04-23 | 2018-08-07 | 广州赛莱拉干细胞科技股份有限公司 | Composition containing yellow tang extract and its cosmetics |
| CN109498521A (en) * | 2018-12-23 | 2019-03-22 | 广州素颜皮肤管理科技有限公司 | It is a kind of to have effects that the plant extracts of antiallergy and its application |
| CN112057359A (en) * | 2020-10-22 | 2020-12-11 | 北京唯爱生物科技有限公司 | Deep-sea pinus hirsuta moisturizing composition and preparation method and application thereof |
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| CN108371639A (en) * | 2018-04-23 | 2018-08-07 | 广州赛莱拉干细胞科技股份有限公司 | Composition containing yellow tang extract and its cosmetics |
| CN109498521A (en) * | 2018-12-23 | 2019-03-22 | 广州素颜皮肤管理科技有限公司 | It is a kind of to have effects that the plant extracts of antiallergy and its application |
| CN112057359A (en) * | 2020-10-22 | 2020-12-11 | 北京唯爱生物科技有限公司 | Deep-sea pinus hirsuta moisturizing composition and preparation method and application thereof |
| CN112057359B (en) * | 2020-10-22 | 2021-07-27 | 北京唯爱生物科技有限公司 | Deep-sea pinus hirsuta moisturizing composition and preparation method and application thereof |
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| CN106491455B (en) | 2019-12-31 |
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