CN106490608A - A kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet - Google Patents
A kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet Download PDFInfo
- Publication number
- CN106490608A CN106490608A CN201610880985.0A CN201610880985A CN106490608A CN 106490608 A CN106490608 A CN 106490608A CN 201610880985 A CN201610880985 A CN 201610880985A CN 106490608 A CN106490608 A CN 106490608A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba dendrobii
- powder
- oral liquid
- enhancing immunity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 39
- 230000036039 immunity Effects 0.000 title claims abstract description 26
- 230000002708 enhancing effect Effects 0.000 title claims abstract description 22
- 239000002775 capsule Substances 0.000 title claims abstract description 7
- -1 electuary Substances 0.000 title abstract description 5
- 239000000843 powder Substances 0.000 claims abstract description 52
- 241000192656 Nostoc Species 0.000 claims abstract description 18
- 239000000284 extract Substances 0.000 claims abstract description 16
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 15
- 239000008176 lyophilized powder Substances 0.000 claims abstract description 15
- 229940096421 milk thistle extract Drugs 0.000 claims abstract description 14
- 235000020727 milk thistle extract Nutrition 0.000 claims abstract description 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 12
- 240000002900 Arthrospira platensis Species 0.000 claims abstract description 9
- 235000016425 Arthrospira platensis Nutrition 0.000 claims abstract description 9
- 240000007817 Olea europaea Species 0.000 claims abstract description 9
- 235000002725 Olea europaea Nutrition 0.000 claims abstract description 9
- 229940082787 spirulina Drugs 0.000 claims abstract description 9
- 241000169546 Lycium ruthenicum Species 0.000 claims abstract description 8
- 241000628997 Flos Species 0.000 claims abstract description 7
- 240000006927 Foeniculum vulgare Species 0.000 claims abstract description 7
- 235000004204 Foeniculum vulgare Nutrition 0.000 claims abstract description 7
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000009636 Huang Qi Substances 0.000 claims abstract description 6
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 6
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 6
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 6
- 230000001413 cellular effect Effects 0.000 claims abstract description 6
- 229930002875 chlorophyll Natural products 0.000 claims abstract description 6
- 235000019804 chlorophyll Nutrition 0.000 claims abstract description 6
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims abstract description 6
- 235000008434 ginseng Nutrition 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 6
- 239000011718 vitamin C Substances 0.000 claims abstract description 6
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract 2
- 238000004880 explosion Methods 0.000 claims description 29
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 18
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 102000004190 Enzymes Human genes 0.000 claims description 9
- 108090000790 Enzymes Proteins 0.000 claims description 9
- 239000006228 supernatant Substances 0.000 claims description 9
- 108090000145 Bacillolysin Proteins 0.000 claims description 6
- 102000035092 Neutral proteases Human genes 0.000 claims description 6
- 108091005507 Neutral proteases Proteins 0.000 claims description 6
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 235000019634 flavors Nutrition 0.000 claims description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims description 6
- 239000011347 resin Substances 0.000 claims description 6
- 229920005989 resin Polymers 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 108091005804 Peptidases Proteins 0.000 claims description 5
- 239000004365 Protease Substances 0.000 claims description 5
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 5
- 238000000855 fermentation Methods 0.000 claims description 5
- 230000004151 fermentation Effects 0.000 claims description 5
- 230000007062 hydrolysis Effects 0.000 claims description 4
- 238000006460 hydrolysis reaction Methods 0.000 claims description 4
- 239000003960 organic solvent Substances 0.000 claims description 4
- 241000194108 Bacillus licheniformis Species 0.000 claims description 3
- 241000186226 Corynebacterium glutamicum Species 0.000 claims description 3
- 241000186660 Lactobacillus Species 0.000 claims description 3
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical class CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 3
- 241000320380 Silybum Species 0.000 claims description 3
- 235000010841 Silybum marianum Nutrition 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- 239000008367 deionised water Substances 0.000 claims description 3
- 229910021641 deionized water Inorganic materials 0.000 claims description 3
- 238000013461 design Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 239000003480 eluent Substances 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 3
- 238000011081 inoculation Methods 0.000 claims description 3
- 239000002054 inoculum Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000006213 oxygenation reaction Methods 0.000 claims description 3
- 238000001556 precipitation Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 238000004064 recycling Methods 0.000 claims description 3
- 210000000582 semen Anatomy 0.000 claims description 3
- 238000000926 separation method Methods 0.000 claims description 3
- 238000001179 sorption measurement Methods 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 238000010792 warming Methods 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 238000004080 punching Methods 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 230000001737 promoting effect Effects 0.000 abstract description 5
- 239000008280 blood Substances 0.000 abstract description 3
- 210000004369 blood Anatomy 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 230000001502 supplementing effect Effects 0.000 abstract description 2
- 235000013376 functional food Nutrition 0.000 description 6
- 241000208340 Araliaceae Species 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000006872 improvement Effects 0.000 description 3
- 241000779819 Syncarpia glomulifera Species 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000001739 pinus spp. Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 229940036248 turpentine Drugs 0.000 description 2
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 101710180316 Protease 2 Proteins 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet, the oral liquid is prepared from by the raw material of following weight portion：30 40 parts of Herba Dendrobii lyophilized powder, 10 20 parts of Olive leaf P.E, 10 15 parts of Milk Thistle extract, 10 15 parts of vitamin C, 10 20 parts of breaking cellular wall Spirulina powder, 58 parts of chlorophyll, 20 30 parts of Herba Dendrobii extracting solution, 5 10 parts of Sucus Zingberis, 5 10 parts of Fructus Crataegi powder, 35 parts of fennel powder, 36 parts of Flos Chrysanthemi powder, 59 parts of Lycium ruthenicum Murr. extract, 10 15 parts of Nostoc yeast powder, 5 10 parts of Radix Ginseng, 5 10 parts of the Radix Astragali.The present invention cooperates with the interpolation of Olive leaf P.E, breaking cellular wall Spirulina powder, Nostoc yeast powder etc., can significantly improve the immunity of human body with homemade Herba Dendrobii lyophilized powder and Herba Dendrobii extracting solution as main component；Concrete preferably blood circulation promoting and blood stasis dispelling, effect of supplementing QI and nourishing YIN, and eater is difficult to get angry.
Description
Technical field
The present invention relates to field of health care products, and in particular to a kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet.
Background technology
With society and economic progress, the improvement of people's living standards, the development of science and technology, the change of disease pattern
And the pursuit to having good health and a long life, the functional food of enhancing immunity gradually deep people's popular feeling, people are had started to from treating again
Turn to and prevent again, this will be greatly promoted the development of the functional food of enhancing immunity.21 century will be that functional food is big
The century that displays one's abilities.China has the huge treasure-house of Chinese herbal medicine this functional food and other characteristic resources, and we should combine
The functional food development trend of enhancing immunity and the impetus of China's development, make great efforts to excavate these precious resources, develop
The functional food of enhancing immunity with Chinese characteristics, to obtain due status in fierce international competition.
According to historical document and modern study it is experimentally confirmed that effect for oral administration of Herba Dendrobii mainly has：Yin-nourishing and body fluid promoting maintenance five
Dirty, health invigorating, enhance immunity, strengthening the tendons and bones, opposing rheumatism, strengthen the spleen and stomach, function of gallbladder promoting, control liver and gall diseases, prevent and treat diabetes,
Suppress tumor, reduce Radiotherapy chemotherapy side effect, item eye protection, and moisturizing skin moistening, life lengthening etc..
Content of the invention
For solving the above problems, the invention provides a kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet, with
Homemade Herba Dendrobii lyophilized powder and Herba Dendrobii extracting solution are main component, collaboration Olive leaf P.E, breaking cellular wall Spirulina powder,
The interpolation of Nostoc yeast powder etc., can significantly improve the immunity of human body；Extracted by Milk Thistle extract, Lycium ruthenicum Murr.
Thing, Sucus Zingberis, Fructus Crataegi powder, fennel powder, the synergism of Flos Chrysanthemi powder, concrete preferably blood circulation promoting and blood stasis dispelling, effect of supplementing QI and nourishing YIN, and
So that eater is difficult to get angry.
For achieving the above object, the technical scheme taken of the present invention is：
A kind of Herba Dendrobii enhancing immunity oral liquid, is prepared from by the raw material of following weight portion：
Herba Dendrobii lyophilized powder 30-40 parts, Olive leaf P.E 10-20 parts, Milk Thistle extract 10-15 parts, vitamin C
10-15 parts, breaking cellular wall Spirulina powder 10-20 parts, chlorophyll 5-8 parts, Herba Dendrobii extracting solution 20-30 parts, Sucus Zingberis 5-10 parts, Fructus Crataegi
Powder 5-10 parts, fennel powder 3-5 part, Flos Chrysanthemi powder 3-6 parts, Lycium ruthenicum Murr. extract 5-9 parts, Nostoc yeast powder 10-15 parts, Radix Ginseng
5-10 parts, Radix Astragali 5-10 parts.
Preferably, the Herba Dendrobii lyophilized powder prepares gained by following steps：
S1, the Herba Dendrobii that drains will be cleaned it is placed in steam-explosion jar, it is 0.6- to be first passed through nitrogen to steam explosion pressure inside the tank
1.4MPa, explosion treatment 8-25min；Then it is 1.4-1.8MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.5-2.5min, room temperature is concentrated into relative density 1.10-1.20, is spray-dried concentrated solution, obtains powder body；
S2, in powder body add 3-8 times of water, by mass percentage be 2-3% ratio add neutral protease, by quality
Percentage ratio is that 1-2% adds flavor protease, digests 1-2h, filter, obtain enzymolysis solution at 30-50 DEG C；
S3, by naturally to thaw again after the fermentation liquid quick freeze of gained, make age of starch precipitation in extract；Collect supernatant
Liquid, remainder are centrifuged, and collect centrifugal liquid and are incorporated in supernatant；
S4, by supernatant with the flow velocity of 3-7BV/h by macroporous resin column, after dynamic adsorption saturation, deionized water with
The above-mentioned macroporous resin column of the flow velocity drip washing of 5-8BV/h is colourless to effluent, then with the organic solvent that volume fraction is 50%-70%
Eluting is carried out with the flow velocity of 8-12BV/h, eluent is collected, lyophilization obtains Herba Dendrobii lyophilized powder.
Preferably, the Milk Thistle extract prepares gained by following steps：
Dry Milk Thistle is placed in 90% methanol or ethanol solution that flash extracter adds 6 times of volumes, 1-3 point is processed
Clock, after solid-liquid separation, reclaims methanol or ethanol solution, concentration so that extract is in paste, then with water-saturated n-butanol to carrying
Take thing to extract 3 times, after recycling design, by drying concentrated in vacuo for extract, obtain Milk Thistle extract.
Preferably, the Herba Dendrobii extracting solution prepares gained by following steps：
S1, by clean Herba Dendrobii be placed in flash extracter process after, by mass percentage be 3-5% add compound enzyme
Solution liquid, digests 1～2 hour by 20-30 DEG C, and per half an hour, once, control pH value is between 3.5～6.2 for stirring, oxygenation；
Enzymolysis solution is warming up to 85～100 DEG C after terminating by S2, enzymolysis, and enzyme denaturing 30～40 minutes filters, obtains Herba Dendrobii and carry
Take liquid.
Preferably, the Nostoc yeast powder prepares gained by following steps：
Take the Nostoc that cleans after draining to be placed in steam-explosion jar, it is 0.7- to be first passed through nitrogen to steam explosion pressure inside the tank
1.5MPa, explosion treatment 7-23min；Then it is 1.5-2.1MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.8-2.8min, according to the ratio microbe inoculation leaven of inoculum concentration 1.5-1.7%, keeping temperature 25-35 DEG C, fermentation
After 48-54 hours, high temperature sterilize obtains Nostoc yeast powder.
Preferably, the microbe leaven is by lactobacilluss, Bacillus licheniformis, Corynebacterium glutamicum in mass ratio 3:
2:1 mixing gained.
Preferably, component of the complex enzyme hydrolysis liquid comprising following weight portion：
3～5 parts of neutral protease, 2～5 parts of flavor protease, 15 parts of paraplasm.
Preferably, the paraplasm includes 10% Sucus Granati, the Semen Maydis pulp of 2.5 parts of Fructus Lycopersici esculenti juice and 2.5 parts.
Preferably, above-mentioned formula can also be fabricated to electuary, capsule or tablet.
The invention has the advantages that：
With homemade Herba Dendrobii lyophilized powder and Herba Dendrobii extracting solution as main component, cooperate with Olive leaf P.E, break
The interpolation of wall Spirulina powder, Nostoc yeast powder etc., can significantly improve the immunity of human body；By Milk Thistle extract,
Lycium ruthenicum Murr. extract, Sucus Zingberis, Fructus Crataegi powder, fennel powder, the synergism of Flos Chrysanthemi powder, concrete preferably blood circulation promoting and blood stasis dispelling, QI invigorating are supported
Cloudy effect, and cause eater to be difficult to get angry.
Specific embodiment
In order that objects and advantages of the present invention become more apparent, with reference to embodiments the present invention is carried out further
Describe in detail.It should be appreciated that specific embodiment described herein is not used to limit this only in order to explain the present invention
Bright.
Following examples, the Herba Dendrobii lyophilized powder for being used prepare gained by following steps：
S1, the Herba Dendrobii that drains will be cleaned it is placed in steam-explosion jar, it is 0.6- to be first passed through nitrogen to steam explosion pressure inside the tank
1.4MPa, explosion treatment 8-25min；Then it is 1.4-1.8MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.5-2.5min, room temperature is concentrated into relative density 1.10-1.20, is spray-dried concentrated solution, obtains powder body；
S2, in powder body add 3-8 times of water, by mass percentage be 2-3% ratio add neutral protease, by quality
Percentage ratio is that 1-2% adds flavor protease, digests 1-2h, filter, obtain enzymolysis solution at 30-50 DEG C；
S3, by naturally to thaw again after the fermentation liquid quick freeze of gained, make age of starch precipitation in extract；Collect supernatant
Liquid, remainder are centrifuged, and collect centrifugal liquid and are incorporated in supernatant；
S4, by supernatant with the flow velocity of 3-7BV/h by macroporous resin column, after dynamic adsorption saturation, deionized water with
The above-mentioned macroporous resin column of the flow velocity drip washing of 5-8BV/h is colourless to effluent, then with the organic solvent that volume fraction is 50%-70%
Eluting is carried out with the flow velocity of 8-12BV/h, eluent is collected, lyophilization obtains Herba Dendrobii lyophilized powder.
The Milk Thistle extract for being used prepares gained by following steps：
Dry Milk Thistle is placed in 90% methanol or ethanol solution that flash extracter adds 6 times of volumes, 1-3 point is processed
Clock, after solid-liquid separation, reclaims methanol or ethanol solution, concentration so that extract is in paste, then with water-saturated n-butanol to carrying
Take thing to extract 3 times, after recycling design, by drying concentrated in vacuo for extract, obtain Milk Thistle extract.
The Herba Dendrobii extracting solution for being used prepares gained by following steps：
S1, by clean Herba Dendrobii be placed in flash extracter process after, by mass percentage be 3-5% add compound enzyme
Solution liquid, digests 1～2 hour by 20-30 DEG C, and per half an hour, once, control pH value is between 3.5～6.2 for stirring, oxygenation；
Enzymolysis solution is warming up to 85～100 DEG C after terminating by S2, enzymolysis, and enzyme denaturing 30～40 minutes filters, obtains Herba Dendrobii and carry
Take liquid；Wherein, component of the complex enzyme hydrolysis liquid comprising following weight portion：3～5 parts of neutral protease, flavor protease 2～5
Part, 15 parts of paraplasm；The paraplasm includes 10 parts of Sucus Granati, the Semen Maydis pulp of 2.5 parts of Fructus Lycopersici esculenti juice and 2.5 parts.
The Nostoc yeast powder for being used prepares gained by following steps：
Take the Nostoc that cleans after draining to be placed in steam-explosion jar, it is 0.7- to be first passed through nitrogen to steam explosion pressure inside the tank
1.5MPa, explosion treatment 7-23min；Then it is 1.5-2.1MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.8-2.8min, according to the ratio microbe inoculation leaven of inoculum concentration 1.5-1.7%, keeping temperature 25-35 DEG C, fermentation
After 48-54 hours, high temperature sterilize obtains Nostoc yeast powder, the microbe leaven by lactobacilluss, Bacillus licheniformis,
Corynebacterium glutamicum in mass ratio 3:2:1 mixing gained.
Turpentine derivatives of the organic solvent for natural origin.Isomery, discrimination of the turpentine derivatives for pinene
Change product.
Embodiment 1
A kind of Herba Dendrobii enhancing immunity oral liquid, is prepared from by the raw material of following weight portion：
30 parts of Herba Dendrobii lyophilized powder, 10 parts of Olive leaf P.E, 10 parts of Milk Thistle extract, 10 parts of vitamin C, broken
10 parts of wall Spirulina powder, 5 parts of chlorophyll, 20 parts of Herba Dendrobii extracting solution, 5 parts of Sucus Zingberis, 5 parts of Fructus Crataegi powder, 3 parts of fennel powder, chrysanthemum
3 parts of pollen, 5 parts of Lycium ruthenicum Murr. extract, 10 parts of Nostoc yeast powder, 5 parts of Radix Ginseng, 5 parts of the Radix Astragali.
Embodiment 2
A kind of Herba Dendrobii enhancing immunity oral liquid, is prepared from by the raw material of following weight portion：
40 parts of Herba Dendrobii lyophilized powder, 20 parts of Olive leaf P.E, 15 parts of Milk Thistle extract, 15 parts of vitamin C, broken
20 parts of wall Spirulina powder, 8 parts of chlorophyll, 30 parts of Herba Dendrobii extracting solution, 10 parts of Sucus Zingberis, 10 parts of Fructus Crataegi powder, 5 parts of fennel powder,
6 parts of Flos Chrysanthemi powder, 9 parts of Lycium ruthenicum Murr. extract, 15 parts of Nostoc yeast powder, 10 parts of Radix Ginseng, 10 parts of the Radix Astragali.
Embodiment 3
A kind of Herba Dendrobii enhancing immunity oral liquid, is prepared from by the raw material of following weight portion：
35 parts of Herba Dendrobii lyophilized powder, 15 parts of Olive leaf P.E, 12.5 parts of Milk Thistle extract, vitamin C 12.5
Part, 15 parts of breaking cellular wall Spirulina powder, 6.5 parts of chlorophyll, 25 parts of Herba Dendrobii extracting solution, 7.5 parts of Sucus Zingberis, 7.5 parts of Fructus Crataegi powder, Fructus Foeniculi
4 parts of XIANGFEN, 4.5 parts of Flos Chrysanthemi powder, 7 parts of Lycium ruthenicum Murr. extract, 12.5 parts of Nostoc yeast powder, 7.5 parts of Radix Ginseng, 7.5 parts of the Radix Astragali.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (9)
1. a kind of Herba Dendrobii enhancing immunity oral liquid, it is characterised in that be prepared from by the raw material of following weight portion：
Herba Dendrobii lyophilized powder 30-40 parts, Olive leaf P.E 10-20 parts, Milk Thistle extract 10-15 parts, vitamin C 10-
15 parts, breaking cellular wall Spirulina powder 10-20 parts, chlorophyll 5-8 parts, Herba Dendrobii extracting solution 20-30 parts, Sucus Zingberis 5-10 parts, Fructus Crataegi powder
5-10 parts, fennel powder 3-5 part, Flos Chrysanthemi powder 3-6 parts, Lycium ruthenicum Murr. extract 5-9 parts, Nostoc yeast powder 10-15 parts, Radix Ginseng 5-
10 parts, Radix Astragali 5-10 parts.
2. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 1, it is characterised in that the Herba Dendrobii lyophilized powder
Gained is prepared by following steps：
S1, the Herba Dendrobii that drains will be cleaned it is placed in steam-explosion jar, it is 0.6-1.4MPa to be first passed through nitrogen to steam explosion pressure inside the tank,
Explosion treatment 8-25min；Then it is 1.4-1.8MPa, Steam explosion treatment 0.5- to be passed through rapidly steam to steam explosion pressure inside the tank
After 2.5min, room temperature is concentrated into relative density 1.10-1.20, is spray-dried concentrated solution, obtains powder body；
S2, in powder body add 3-8 times of water, by mass percentage be 2-3% ratio add neutral protease, by quality percentage
Than flavor protease being added for 1-2%, digest 1-2h at 30-50 DEG C, filter, obtain enzymolysis solution；
S3, by naturally to thaw again after the fermentation liquid quick freeze of gained, make age of starch precipitation in extract；Collect supernatant,
Remainder is centrifuged, and collects centrifugal liquid and is incorporated in supernatant；
S4, by supernatant with the flow velocity of 3-7BV/h by macroporous resin column, after dynamic adsorption saturation, deionized water is with 5-
The above-mentioned macroporous resin column of the flow velocity drip washing of 8BV/h is colourless to effluent, then with the organic solvent that volume fraction is 50%-70% with
The flow velocity of 8-12BV/h carries out eluting, collects eluent, and lyophilization obtains Herba Dendrobii lyophilized powder.
3. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 1, it is characterised in that the Milk Thistle extract leads to
Cross following steps and prepare gained：
Dry Milk Thistle is placed in 90% methanol or ethanol solution that flash extracter adds 6 times of volumes, 1-3 minutes are processed,
After solid-liquid separation, methanol or ethanol solution, concentration is reclaimed so that extract is in paste, then with water-saturated n-butanol to extracting
Thing is extracted 3 times, after recycling design, by drying concentrated in vacuo for extract, obtains Milk Thistle extract.
4. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 1, it is characterised in that the Herba Dendrobii extracting solution
Gained is prepared by following steps：
S1, by clean Herba Dendrobii be placed in flash extracter process after, by mass percentage be 3-5% add complex enzyme hydrolysis
Liquid, digests 1～2 hour by 20-30 DEG C, and per half an hour, once, control pH value is between 3.5～6.2 for stirring, oxygenation；
Enzymolysis solution is warming up to 85～100 DEG C after terminating by S2, enzymolysis, and enzyme denaturing 30～40 minutes is filtered, and obtains Herba Dendrobii extraction
Liquid.
5. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 1, it is characterised in that the Nostoc yeast powder leads to
Cross following steps and prepare gained：
Take the Nostoc that cleans after draining to be placed in steam-explosion jar, it is 0.7-1.5MPa to be first passed through nitrogen to steam explosion pressure inside the tank, quick-fried
Tear manages 7-23min；Then it is 1.5-2.1MPa, Steam explosion treatment 0.8- to be passed through rapidly steam to steam explosion pressure inside the tank
After 2.8min, according to the ratio microbe inoculation leaven of inoculum concentration 1.5-1.7%, keeping temperature 25-35 DEG C, ferment 48-54
After hour, high temperature sterilize obtains Nostoc yeast powder.
6. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 5, it is characterised in that the microbe leaven by
Lactobacilluss, Bacillus licheniformis, Corynebacterium glutamicum in mass ratio 3:2:1 mixing gained.
7. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 4, it is characterised in that the complex enzyme hydrolysis liquid includes
The component of following weight portion：
3～5 parts of neutral protease, 2～5 parts of flavor protease, 15 parts of paraplasm.
8. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 7, it is characterised in that the paraplasm includes
10% Sucus Granati, the Semen Maydis pulp of 2.5 parts of Fructus Lycopersici esculenti juice and 2.5 parts.
9. a kind of Herba Dendrobii enhancing immunity oral liquid as claimed in claim 1, it is characterised in that above-mentioned with punching can be fabricated to
Agent, capsule or tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610880985.0A CN106490608A (en) | 2016-10-09 | 2016-10-09 | A kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610880985.0A CN106490608A (en) | 2016-10-09 | 2016-10-09 | A kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106490608A true CN106490608A (en) | 2017-03-15 |
Family
ID=58294695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610880985.0A Pending CN106490608A (en) | 2016-10-09 | 2016-10-09 | A kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106490608A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106924456A (en) * | 2017-03-26 | 2017-07-07 | 大理大学 | One kind is for activating mitochondrial composition |
| CN107149145A (en) * | 2017-04-29 | 2017-09-12 | 吉首大学 | A kind of bark of eucommia fatigue resistant health food and preparation method thereof |
| CN107149080A (en) * | 2017-05-11 | 2017-09-12 | 郑州科技学院 | A kind of microcapsule food preservative and preparation method thereof |
| CN108671067A (en) * | 2018-07-27 | 2018-10-19 | 吉林大学珠海学院 | A kind of oxidation resistant compound Chinese medicine extraction isolate and preparation method thereof |
| CN109043143A (en) * | 2018-11-07 | 2018-12-21 | 辽宁职业学院 | A kind of selenium-rich edible fungi residue feed and its application |
| CN109336988A (en) * | 2018-10-19 | 2019-02-15 | 贵州真阳纳米医药科技有限公司 | A kind of extracting method of dendrobium candidum |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028754A (en) * | 2010-11-19 | 2011-04-27 | 沈阳药科大学 | Method for rapidly preparing total lignans and total saponins from schisandra chinensis |
| CN104800591A (en) * | 2015-04-15 | 2015-07-29 | 威海御膳坊生物科技有限公司 | Oral Dendrobium officinale compound preparation |
| CN104844723A (en) * | 2015-06-05 | 2015-08-19 | 云南金九地生物科技有限公司 | Preparation method and application of dendrobium officinale extract |
| CN105254773A (en) * | 2015-10-27 | 2016-01-20 | 齐齐哈尔医学院 | Preparation method of antitumor polysaccharide |
| CN105341917A (en) * | 2015-11-17 | 2016-02-24 | 安徽千方生物科技有限公司 | Cell nutrition enhancing health product preparation and preparation method thereof |
| CN105748764A (en) * | 2016-03-12 | 2016-07-13 | 华北理工大学 | Traditional Chinese medicine composition with antibacterial and anti-inflammation effects and preparation method of composition |
| CN105796892A (en) * | 2016-05-27 | 2016-07-27 | 陕西国际商贸学院 | Traditional Chinese medicine extractive composition and preparation method thereof |
-
2016
- 2016-10-09 CN CN201610880985.0A patent/CN106490608A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028754A (en) * | 2010-11-19 | 2011-04-27 | 沈阳药科大学 | Method for rapidly preparing total lignans and total saponins from schisandra chinensis |
| CN104800591A (en) * | 2015-04-15 | 2015-07-29 | 威海御膳坊生物科技有限公司 | Oral Dendrobium officinale compound preparation |
| CN104844723A (en) * | 2015-06-05 | 2015-08-19 | 云南金九地生物科技有限公司 | Preparation method and application of dendrobium officinale extract |
| CN105254773A (en) * | 2015-10-27 | 2016-01-20 | 齐齐哈尔医学院 | Preparation method of antitumor polysaccharide |
| CN105341917A (en) * | 2015-11-17 | 2016-02-24 | 安徽千方生物科技有限公司 | Cell nutrition enhancing health product preparation and preparation method thereof |
| CN105748764A (en) * | 2016-03-12 | 2016-07-13 | 华北理工大学 | Traditional Chinese medicine composition with antibacterial and anti-inflammation effects and preparation method of composition |
| CN105796892A (en) * | 2016-05-27 | 2016-07-27 | 陕西国际商贸学院 | Traditional Chinese medicine extractive composition and preparation method thereof |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106924456A (en) * | 2017-03-26 | 2017-07-07 | 大理大学 | One kind is for activating mitochondrial composition |
| CN107149145A (en) * | 2017-04-29 | 2017-09-12 | 吉首大学 | A kind of bark of eucommia fatigue resistant health food and preparation method thereof |
| CN107149080A (en) * | 2017-05-11 | 2017-09-12 | 郑州科技学院 | A kind of microcapsule food preservative and preparation method thereof |
| CN108671067A (en) * | 2018-07-27 | 2018-10-19 | 吉林大学珠海学院 | A kind of oxidation resistant compound Chinese medicine extraction isolate and preparation method thereof |
| CN109336988A (en) * | 2018-10-19 | 2019-02-15 | 贵州真阳纳米医药科技有限公司 | A kind of extracting method of dendrobium candidum |
| CN109043143A (en) * | 2018-11-07 | 2018-12-21 | 辽宁职业学院 | A kind of selenium-rich edible fungi residue feed and its application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106490608A (en) | A kind of Herba Dendrobii enhancing immunity oral liquid, electuary, capsule, tablet | |
| CN101961371B (en) | Method for extracting and separating ginsenoside, flavone and polysaccharide from sweet gynostemma pentaphylla | |
| CN103146560B (en) | Health-care vinegar and preparation method thereof | |
| CN104292352B (en) | A kind of Cortex Eucommiae fine powder, eucommia bark polycose and gutta-percha coproduction extraction separation method | |
| CN107149145A (en) | A kind of bark of eucommia fatigue resistant health food and preparation method thereof | |
| CN106309329A (en) | Dendrobe combined eye cream for promoting skin regeneration | |
| CN105901719A (en) | Donkey-hide gelatin with effects of invigorating qi, nourishing blood, beautifying face and losing weight and preparation method thereof | |
| CN111253495A (en) | Extraction process of dendrobe polysaccharide and dendrobine in dendrobium officinale | |
| CN106344485A (en) | Herba dendrobii essence facial mask | |
| CN106472918A (en) | A kind of Herba Dendrobii antioxidation beverage | |
| CN106832021A (en) | A kind of preparation method of Chinese cassia tree slag Thick many candies | |
| CN105061368A (en) | Method for extracting vitamin C from rose | |
| CN105746772A (en) | Preparation method of sweet potato leaf health tea with effect of lowering blood glucose | |
| CN109170885A (en) | A method of extracting ginseng effective component | |
| CN106490600A (en) | A kind of Herba Dendrobii compound tablet, injection, electuary | |
| CN105031289A (en) | Dendrobium officinale and lucid ganoderma capsules and preparation method thereof | |
| CN106511236A (en) | Skin regeneration promotion and ageing prevention Dendrobium huoshanense preparation | |
| CN111840466A (en) | Medical health-care product for enhancing immunity and assisting in treating tumors and preparation method thereof | |
| CN103961388B (en) | A kind of preparation method of radix cynanchi bungei total saponin | |
| CN105399852A (en) | Technology for producing radix astragali polysaccharide by utilization of alkaline process extraction technology | |
| CN106805064A (en) | A kind of health beverages for supplementing physical efficiency | |
| CN106723019A (en) | A kind of Dendrobidium huoshanness strengthen immunity preparation and oral liquid, electuary, capsule, tablet | |
| CN106722981A (en) | A kind of health food of Dendrobidium huoshanness | |
| CN103960386A (en) | Mythic fungus dark tea and processing method thereof | |
| CN106892993A (en) | A kind of preparation method of honey raisin tree slag Thick many candies |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170315 |
|
| RJ01 | Rejection of invention patent application after publication |