CN106471134B - 用于定量rna转录物变体的方法和产物 - Google Patents

用于定量rna转录物变体的方法和产物 Download PDF

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CN106471134B
CN106471134B CN201580035408.5A CN201580035408A CN106471134B CN 106471134 B CN106471134 B CN 106471134B CN 201580035408 A CN201580035408 A CN 201580035408A CN 106471134 B CN106471134 B CN 106471134B
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molecules
transcript
sequence
rna
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CN106471134A (zh
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L·保罗
P·库巴拉
T·莱达
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Lexogen GmbH
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CN201580035408.5A 2014-07-09 2015-07-09 用于定量rna转录物变体的方法和产物 Active CN106471134B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14176417 2014-07-09
EP14176417.5 2014-07-09
PCT/EP2015/065756 WO2016005524A1 (en) 2014-07-09 2015-07-09 Methods and products for quantifying rna transcript variants

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CN106471134A CN106471134A (zh) 2017-03-01
CN106471134B true CN106471134B (zh) 2021-11-12

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US (1) US10513726B2 (https=)
EP (1) EP3167076B1 (https=)
JP (3) JP6930910B2 (https=)
KR (1) KR102555447B1 (https=)
CN (1) CN106471134B (https=)
AU (1) AU2015286672B2 (https=)
CA (1) CA2954495C (https=)
DK (1) DK3167076T3 (https=)
LT (1) LT3167076T (https=)
WO (1) WO2016005524A1 (https=)

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DK2756098T3 (en) 2011-09-16 2018-09-03 Lexogen Gmbh Process for Preparing a Library of Nucleic Acid Molecules
WO2016005524A1 (en) 2014-07-09 2016-01-14 Lexogen Gmbh Methods and products for quantifying rna transcript variants
CN106771194B (zh) * 2017-01-18 2018-07-20 青岛大学 一种检测病原微生物的方法
US12440578B2 (en) 2017-02-22 2025-10-14 Io Biosciences, Inc. Nucleic acid constructs comprising gene editing multi-sites and uses thereof
US10828330B2 (en) * 2017-02-22 2020-11-10 IO Bioscience, Inc. Nucleic acid constructs comprising gene editing multi-sites and uses thereof
SE541799C2 (en) * 2018-04-11 2019-12-17 David Yudovich Determination of frequency distribution of nucleotide sequence variants
CA3097004A1 (en) 2018-04-17 2019-10-24 The Trustees Of The University Of Pennsylvania Trans-splicing molecules
CN116804222A (zh) * 2018-05-02 2023-09-26 北京康普森生物技术有限公司 一种基于snp分子标记鉴定滩羊与非滩羊的方法
EP3666904A1 (en) 2018-12-14 2020-06-17 Lexogen GmbH Nucleic acid amplification and identification method
EP3901284A1 (en) * 2020-04-20 2021-10-27 BMBK Invest BV Construct, kit and method for sample tracking
KR102690574B1 (ko) 2020-06-26 2024-07-31 숙명여자대학교산학협력단 비타민 b1의 보호 및 전달을 위한 장용성 조성물
KR102690573B1 (ko) 2020-06-26 2024-07-31 숙명여자대학교산학협력단 사이클로덱스트린을 이용한 경구투여용 복합 조성물 및 이의 제조방법
WO2023086441A1 (en) * 2021-11-12 2023-05-19 Regents Of The University Of Minnesota Compositions and methods for transcriptional activation
EP4438741A4 (en) * 2021-11-26 2025-08-06 Daan Gene Co Ltd HIGH-THROUGHPUT SEQUENCING METHOD BASED ON THE INTERNAL REFERENCE OF A KNOWN MARKER
AU2023269865A1 (en) * 2022-05-13 2024-11-21 Ascidian Therapeutics, Inc. Abca4 trans-splicing molecules

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US20020110828A1 (en) * 2001-01-12 2002-08-15 Ferea Tracy L. Methods and compositions for microarray control
US20070072189A1 (en) * 2004-03-11 2007-03-29 The Government Of The United States Of America As Artificial mutation controls for diagnostic testing
CN102782152A (zh) * 2009-12-11 2012-11-14 莱克斯奥根有限公司 Rna分析方法

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FR2593343B1 (fr) 1986-01-20 1988-03-25 Thomson Csf Matrice d'elements photosensibles et son procede de fabrication, procede de lecture associe, et application de cette matrice a la prise de vue d'images
CA2446531A1 (en) 2001-05-07 2002-11-14 Amersham Biosciences Corp Design of artificial genes for use as controls in gene expression analysis systems
US20040009512A1 (en) * 2002-05-02 2004-01-15 Manuel Ares Arrays for detection of products of mRNA splicing
WO2016005524A1 (en) 2014-07-09 2016-01-14 Lexogen Gmbh Methods and products for quantifying rna transcript variants

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
US20020110828A1 (en) * 2001-01-12 2002-08-15 Ferea Tracy L. Methods and compositions for microarray control
US20070072189A1 (en) * 2004-03-11 2007-03-29 The Government Of The United States Of America As Artificial mutation controls for diagnostic testing
CN102782152A (zh) * 2009-12-11 2012-11-14 莱克斯奥根有限公司 Rna分析方法

Non-Patent Citations (4)

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Evaluation of External RNA Controls for the Standardisation of Gene Expression Biomarker Measurements;Alison S Devonshire等;《BMC Genomics》;20101124;第11卷(第662期);1-15 *
Simultaneous quantification of alternatively spliced transcripts in a single droplet digital PCR reaction;Bing Sun等;《BioTechniques》;20140630;第56卷(第6期);319-325 *
Synthetic spike-in standards for RNA-seq experiments;Lichun Jiang等;《Genome Research》;20110804;第21卷(第9期);摘要，第1543页右栏第2段，"方法"部分 *
Targeted RNA-Sequencing with Competitive Multiplex-PCR Amplicon Libraries;Thomas M. Blomquist等;《PLOS ONE》;20131113;第8卷(第11期);1-14 *

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HK1231518A1 (zh) 2017-12-22
AU2015286672B2 (en) 2021-12-02
JP2021153588A (ja) 2021-10-07
DK3167076T3 (da) 2022-02-21
CA2954495C (en) 2024-03-05
JP2020014478A (ja) 2020-01-30
EP3167076A1 (en) 2017-05-17
AU2015286672A1 (en) 2016-12-15
JP6930910B2 (ja) 2021-09-01
JP7568581B2 (ja) 2024-10-16
US10513726B2 (en) 2019-12-24
KR20170028383A (ko) 2017-03-13
JP2017525341A (ja) 2017-09-07
CN106471134A (zh) 2017-03-01
WO2016005524A1 (en) 2016-01-14
LT3167076T (lt) 2022-02-10
EP3167076B1 (en) 2021-11-17
CA2954495A1 (en) 2016-01-14
KR102555447B1 (ko) 2023-07-13
US20170321248A1 (en) 2017-11-09

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